Article Publish Status: FREE
Abstract Title:

Antimicrobial activity and substantivity of Uncaria tomentosa in infected root canal dentin.

Abstract Source:

Braz Oral Res. 2016 ;30(1):e61. Epub 2016 Apr 26. PMID: 27119588

Abstract Author(s):

Daniel Rodrigo Herrera, Jorge Enrique Durand-Ramirez, Amanda Falcão, Emmanuel João Leal Nogueira da Silva, Elizabete Brasil Dos Santos, Brenda Paula Figueiredo de Almeida Gomes

Article Affiliation:

Daniel Rodrigo Herrera

Abstract:

The aim of this study was to analyze the antimicrobial activity and substantivity of Uncaria tomentosa Willd DC (cat's claw, CC) in root dentin contaminated with Enterococcus faecalis. Forty-eight human premolars were contaminated with E. faecalis (ATCC 29212) and randomly divided into four groups according to the irrigant used during chemomechanical preparation (CMP): CC group: 2% CC gel; CHX group: 2% chlorhexidine digluconate gel (CHX); NaOCl group: 5.25% sodium hypochlorite (NaOCl); and SS group: sterile saline (SS). Microbiological samples were collected before (S1) and after (S2) CMP and after 7 days (S3). Colony-forming units (CFU/mL) at the different sampling times and comparisons among the groups were statistically analyzed by Wilcoxon and Kruskal-Wallis tests (p<0.05). Significant bacterial reduction was achieved in all groups after CMP (p<0.05). Results show no significant difference between S3 and S2 (p>0.05) in the CC and CHX groups. Bacterial load was higher in S3 than in S2 samples (p<0.05) in the NaOCl and SS groups. Our results suggest antibacterial effect of 2% CC gel against E. faecalis in infected dentin, in addition to antibacterial substantivity of 2% CC and 2% CHX up to 7 days.

Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antimicrobial : CK(776) : AC(352)

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.