The use of infant formula is associated with throat colonization of Haemophilus influenzae. - GreenMedInfo Summary
Incidence of Haemophilus influenzae in the throats of healthy infants with different feeding methods.
Pediatr Int. 1999 Jun;41(3):277-80. PMID: 10365578
Department of Maternal and Child Health, Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan.
BACKGROUND: Haemophilus influenzae is the major cause of otitis media and lower respiratory tract infection in childhood. In the presence of human milk, which contains numerous host defense factors, Haemophilus influenzae may be inhibited in attaching to and colonizing pharyngeal cells. We investigated the incidence of H. influenzae in the throats of 162 healthy infants with different feeding methods: 70 breast-fed, 49 mixed-fed and 43 formula-fed infants. METHODS AND RESULTS: Haemophilus influenzae was identified using standard microbiological procedures and the API NH system. The incidence of H. influenzae in breast-fed infants, mixed-fed infants and formula-fed infants was 0, 0 and 7.0% respectively. CONCLUSION: The results suggest that the colonization of H. influenzae in the throat was inhibited by the presence of breast milk.