Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus.
Front Immunol. 2015 ;6:513. Epub 2015 Oct 12. PMID: 26528285
Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of the recent literature regarding immunoregulatory effects of vitamin D as well as its importance in SLE development, clinical severity, and possible effects of supplementation in disease treatment.