Article Publish Status: FREE
Abstract Title:

Vitamin E is immunostimulatory in calves.

Abstract Source:

J Dairy Sci. 1987 May ;70(5):993-9. PMID: 3597940

Abstract Author(s):

P G Reddy, J L Morrill, H C Minocha, J S Stevenson

Article Affiliation:

P G Reddy


Thirty-two Holstein heifer calves, eight per group, were fed 0, 125, 250 or 500 IU/d of supplemental vitamin E/calf, from birth to 24 wk of age, in order to determine the effect on their immune responses. Overall mean lymphocyte blastogenic responses to various T-cell and B-cell mitogens were higher in supplemented calves than in control calves. Mean concentrations of cortisol in serum were lower in all supplemented calves than in control calves. Antibovine herpes-virus type 1 antibody titer (IgG) at 8 and 9 wk, in response to a commercial modified-live intranasal vaccine at 7 wk, was similar in all treatment groups. At 24 wk, in response to a booster at 21 wk, titer was higher in calves given 125 IU of vitamin E/d than in control calves. Based on the concentrations used, it is concluded that supplementation of conventional rations with 125 IU of vitamin E/d may maximize immune responses in calves and may be cost effective.

Study Type : Animal Study

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