Vitamin E may hold promise for the treatment of acantholysis. - GreenMedInfo Summary
High-dose tocopherol acetate therapy in epidermolysis bullosa siblings of the Cockayne-Touraine type.
J Dermatol. 1993 Nov;20(11):723-5. PMID: 8300945
We have employed a successful therapy for epidermolysis bullosa with high-dose oral tocopherol acetate. Two siblings with dominant dystrophic epidermolysis bullosa of the Cockayne-Touraine type were reported. Both siblings suffered from tense blisters and erosions healing with scars and transient milia on the extremities. Electron microscopic study of the blisters revealed a cleavage beneath the lamina densa in both siblings. High-dose oral tocopherol acetate therapy was administered to them with satisfactory clinical reduction of the blister formation.