andAntimicrobial Activity of(DC.) Stapf. Againstspp. Isolated from Newborn Babies in an Intensive Care Unit.
Microb Drug Resist. 2019 Aug 1. Epub 2019 Aug 1. PMID: 31369340
João Batista Oliveira
Phytotherapy is an emerging topic of health research, with particular focus on studying the efficiency of essential oils as antimicrobials. In this study, we investigated theandsusceptibility ofstrains isolated from newborns tooil. Thesusceptibility of the microorganisms toessential oil was compared with the activities of standard antibiotics administered to newborns using disk diffusion and microdilution methods. Forassessment, 30 Wistar rats were wounded and subjected to infection ofstrain DRJ080, followed by treatment with the antibiotic vancomycin,, or carbopol polymer gel (control) for 11 days.accounted for 23.36% of the 107sp. strains isolated. Both vancomycin and the essential oil ofinhibited the growth of all microorganisms. The minimum inhibitory and bactericidal concentrations for theoil were 0.625 mg/mL in all strains tested. The oil had the same therapeutic effectiveness as vancomycin againstDRJ080 in rats. Thus,strains of newborns are sensitive tooil, bothand, demonstrating its potential as an antibiotic alternative.