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Abstract Title:

Western Diet and the Immune System: An Inflammatory Connection.

Abstract Source:

Immunity. 2019 11 19 ;51(5):794-811. PMID: 31747581

Abstract Author(s):

Anette Christ, Mario Lauterbach, Eicke Latz

Article Affiliation:

Anette Christ

Abstract:

The consumption of Western-type calorically rich diets combined with chronic overnutrition and a sedentary lifestyle in Western societies evokes a state of chronic metabolic inflammation, termed metaflammation. Metaflammation contributes to the development of many prevalent non-communicable diseases (NCDs), and these lifestyle-associated pathologies represent a rising public health problem with global epidemic dimensions. A better understanding of how modern lifestyle and Western diet (WD) activate immune cells is essential for the development of efficient preventive and therapeutic strategies for common NCDs. Here, we review the current mechanistic understanding of how the Western lifestyle can induce metaflammation, and we discuss how this knowledge can be translated to protect the public from the health burden associated with their selected lifestyle.

Study Type : Review
Additional Links
Anti Therapeutic Actions : Western Diet : CK(315) : AC(85)
Adverse Pharmacological Actions : Immunoreactive : CK(167) : AC(33)

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Sayer Ji
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