Wogonin has anti-hepatitis B virus effects. - GreenMedInfo Summary
Anti-hepatitis B virus effects of wogonin isolated from Scutellaria baicalensis.
Planta Med. 2000 Dec ;66(8):694-8. PMID: 11199123
R L Huang
By using an HBV-producing cell line (MS-G2) in vitro culture system, we found that wogonin isolated from Scutellaria baicalensis can suppress HBV surface antigen production (P<0.001) without evidence of cytotoxicity. By assaying the endogenous HBV DNA polymerase activity, we found that both the relaxed circular and the linear forms of HBV DNA are significantly reduced in the wogonin-treated group. Wogonin deserves to be further evaluated for the treatment of human HBV infection.