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Abstract Title:

L. fruit attenuates obesity-associated alterations:mechanisms.

Abstract Source:

Arch Physiol Biochem. 2019 Jun 1:1-8. Epub 2019 Jun 1. PMID: 31155964

Abstract Author(s):

Meryem Berrichi, Chahid Benammar, Babar Murtaza, Aziz Hichami, Meriem Belarbi, Naim Akhtar Khan

Article Affiliation:

Meryem Berrichi

Abstract:

CONTEXT: L., ZL is a Mediterranean plant and widely consumed for its beneficial medicinal properties.

OBJECTIVE: We assessed the effects of ZL fruit on diet-induced obesity.

MATERIALS AND METHODS: Male C57BL/6j mice were divided into three groups. Each group received either a standard diet or a high-fat diet, HFD (30% of palm oil, w/v) or a HFD-supplemented with ZL fruit powder (10%, w/w) for six weeks, followed by a six weeks period, in which animals were maintained on the HFD and ZL aqueous extract (1%, w/v). We measured plasma parameters and assessed the expression of key genes involved in energy metabolism and inflammation.

RESULTS: ZL fruit improved glycaemia, lipids concentrations and inflammation in obese mice.

DISCUSSION AND CONCLUSION: Our investigations showed that ZL fruit improved glucose tolerance, dyslipidaemia and fatty liver disease, but not the severity of HFD-induced obesity in mice.

Study Type : Animal Study

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Sayer Ji
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