Results for Anti-Inflammatory Agents

The dietary ingestion of Aloe sterols protected against chronic UVB damage in mouse skin.

Article Published Date : Dec 19, 2016
Study Type : Animal Study
Additional Links
Substances : Aloe Vera : CK(581) : AC(141)
Diseases : Ultraviolet Radiation Induced Damage : CK(100) : AC(44)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Interleukin-1 beta downregulation : CK(1743) : AC(868), Matrix Metalloproteinase-12 (MMP-12) Inhibitor : CK(2) : AC(1), Matrix Metalloproteinase-13 (MMP-13) Inhibitor : CK(23) : AC(11), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(551) : AC(315), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(543) : AC(337), Photoprotective : CK(74) : AC(27), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(4357) : AC(1763)
Additional Keywords : Aloe vera, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Ultraviolet Radiation Induced Damage

The present review supports that targeting chronic inflammation may have a broad application prospect for the prevention and treatment of cancer.

Article Published Date : May 31, 2017
Study Type : Review
Additional Links
Substances : Andrographolide : CK(3) : AC(3), Curcumin : CK(4844) : AC(2458), Green Tea : CK(2720) : AC(822)
Diseases : Cancers: All : CK(22165) : AC(7896), Inflammation : CK(6531) : AC(1986)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729)
Additional Keywords : Andrographolide, Anti-Inflammatory Agents, Cancers: All, CURCUMIN : CK(2) : AC(1), GREEN TEA, Inflammation : CK(2) : AC(2)

The results show that oleuropein attenuates the progression of heart failure.

Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Oleuropein : CK(195) : AC(112)
Diseases : Heart Failure : CK(1240) : AC(183), Myocardial Infarction : CK(1334) : AC(246), Oxidative Stress : CK(6519) : AC(2436)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Antioxidants : CK(14410) : AC(5758), Interleukin-1 beta downregulation : CK(1743) : AC(868), Malondialdehyde Down-regulation : CK(1452) : AC(466), Superoxide Dismutase Up-regulation : CK(1039) : AC(415), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(4357) : AC(1763)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(1) : AC(1), Heart Failure, Myocardial Infarction, Oleuropein, oxidative stress

The results suggest that horseradish root exerts an antiphlogistic activity in human immune cells.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Horseradish : CK(30) : AC(7)
Diseases : Inflammation : CK(6531) : AC(1986), Lipopolysaccharide-Induced Toxicity : CK(1105) : AC(650)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645), Prostaglandin PGE2 downregulation : CK(187) : AC(83)
Additional Keywords : Anti-Inflammatory Agents, Horseradish, Inflammation : CK(2) : AC(2), Lipopolysaccharide-Induced Toxicity

There is a growing body of evidence that the consumption of pistachios improves health.

Article Published Date : Dec 14, 2017
Study Type : Review
Additional Links
Substances : Pistachio nut : CK(68) : AC(11)
Diseases : Inflammation : CK(6531) : AC(1986)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Antioxidants : CK(14410) : AC(5758)
Additional Keywords : Anti-Inflammatory Agents, Antioxidants : CK(1) : AC(1), Inflammation : CK(2) : AC(2), Pistachio nut

These findings add new experimental data for potential therapeutic effects of resveratrol in the brain in a model of subacute systemic inflammation.

Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Resveratrol : CK(1649) : AC(947)
Diseases : Brain Inflammation : CK(686) : AC(352), Cognitive Decline/Dysfunction : CK(2113) : AC(426)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Neuroprotective Agents : CK(6374) : AC(2801)
Additional Keywords : Anti-Inflammatory Agents, Brain Inflammation, Cognitive Decline/Dysfunction, Dose Response : CK(1519) : AC(574), Neuroprotective Agents, RESVERATROL

These findings demonstrated that MedDiet intervention significantly reduced dietary inflammation scores compared to a low-fat diet.

Article Published Date : Apr 13, 2018
Study Type : Human Study
Additional Links
Diseases : Coronary Artery Disease : CK(1488) : AC(157)
Therapeutic Actions : Dietary Modification: Mediterranean Diet : CK(662) : AC(76)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729)
Additional Keywords : Anti-Inflammatory Agents, Coronary Artery Disease, Dietary Modification: Mediterranean Diet

These findings strongly suggest that the anti-inflammatory actions of Thymoquinone are caused by suppression of IRAK-linked AP-1/NF-κB pathways.

Article Published Date : Feb 19, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymoquinone : CK(386) : AC(227)
Diseases : Inflammation : CK(6531) : AC(1986)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645), Interleukin-1 beta downregulation : CK(1743) : AC(868), Interleukin-6 Downregulation : CK(3054) : AC(1144), NF-kappaB Inhibitor : CK(2446) : AC(1436), Nitric Oxide Inhibitor : CK(390) : AC(196), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(4357) : AC(1763)
Additional Keywords : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(2) : AC(2), Interleukin-1 beta downregulation, thymoquinone

These findings suggested that berberine may reduce insulin resistance.

Article Published Date : Jan 23, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine : CK(732) : AC(384)
Diseases : Insulin Resistance : CK(2804) : AC(602)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Gastrointestinal Agents : CK(268) : AC(41), Hypoglycemic Agents : CK(3297) : AC(841), Hypolipidemic : CK(3189) : AC(707)
Additional Keywords : Anti-Inflammatory Agents, Berberine, Gastrointestinal Agents, Hypoglycemic Agents, Hypolipidemic, Insulin Resistance

These results highlight the protective effects of tangeretin against cisplatin-induced acute hepatic injury.

Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Tangeretin : CK(38) : AC(24)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(612) : AC(266)
Pharmacological Actions : Anti-Apoptotic : CK(1620) : AC(932), Anti-Inflammatory Agents : CK(12461) : AC(4729), Antioxidants : CK(14410) : AC(5758), Chemoprotective Agents : CK(356) : AC(146)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants : CK(1) : AC(1), Chemoprotective Agents, Chemotherapy-Induced Toxicity: Cisplatin

These results indicate that shikonin treatment may prevent the loss of vision associated with diabetic retinopathy.

Article Published Date : Mar 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Diabetic Retinopathy : CK(60) : AC(23)
Pharmacological Actions : Anti-Apoptotic : CK(1620) : AC(932), Anti-Inflammatory Agents : CK(12461) : AC(4729), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Diabetic Retinopathy, Shikonin

These results reveal an immunosuppressive effect of cannabinoid preparations.

Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Cannabinoids : CK(1681) : AC(562)
Diseases : Inflammation : CK(6531) : AC(1986), Pancreatitis: Chronic : CK(4) : AC(4)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Immunosuppressive Agents : CK(37) : AC(24)
Additional Keywords : Anti-Inflammatory Agents, Cannabinoids, Immunosuppressive Agents, Inflammation : CK(2) : AC(2), Pancreatitis: Chronic

These results suggest that ethanolic extracts of adlay had an inhibitory effect on allergic response.

Article Published Date : Feb 23, 2010
Study Type : In Vitro Study
Additional Links
Substances : Adlay : CK(1) : AC(1)
Diseases : Allergies : CK(1076) : AC(205)
Pharmacological Actions : Anti-Allergic Agents : CK(167) : AC(61), Anti-Inflammatory Agents : CK(12461) : AC(4729), Interleukin-4 downregulation : CK(119) : AC(34), Interleukin-6 Downregulation : CK(3054) : AC(1144), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(4357) : AC(1763)
Additional Keywords : Adlay, allergies, Anti-Allergic Agents, Anti-Inflammatory Agents, Plant Extracts : CK(11762) : AC(4236)

These results suggest that tangeretin improves insulin resistance by attenuating obesity-induced inflammation in adipose tissue.

Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin : CK(38) : AC(24)
Diseases : Inflammation : CK(6531) : AC(1986), Insulin Resistance : CK(2804) : AC(602), Obesity : CK(4406) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645), Insulin Sensitizers : CK(707) : AC(139), Interleukin-1 beta downregulation : CK(1743) : AC(868), Interleukin-6 Downregulation : CK(3054) : AC(1144), Nitric Oxide Inhibitor : CK(390) : AC(196)
Additional Keywords : Anti-Inflammatory Agents, Inflammation : CK(2) : AC(2), Insulin Resistance, obesity, Tangeretin

This report confirms the anti-inflammatory potential of this traditionally employed herbal medicine in vitro.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Justicia gendarussa : CK(1) : AC(1)
Diseases : Inflammation : CK(6531) : AC(1986), Lipopolysaccharide-Induced Toxicity : CK(1105) : AC(650)
Pharmacological Actions : 5-Lipoxygenase Inhibitor : CK(8) : AC(7), Anti-Inflammatory Agents : CK(12461) : AC(4729), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645), Interleukin-6 Downregulation : CK(3054) : AC(1144), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Inflammation : CK(2) : AC(2), Interleukin-6 Downregulation, Justicia gendarussa, Lipopolysaccharide-Induced Toxicity, NF-kappaB Inhibitor, Plant Extracts : CK(11762) : AC(4236)

This review aims to summarize an overview on the neuroprotective effects of andrographolide and exemplifies the essential mechanisms involved.

Article Published Date : Jul 26, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Andrographolide : CK(3) : AC(3)
Diseases : Stroke : CK(2223) : AC(307)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Antioxidants : CK(14410) : AC(5758), Heme oxygenase-1 up-regulation : CK(73) : AC(40), Neuroprotective Agents : CK(6374) : AC(2801), NF-kappaB Inhibitor : CK(2446) : AC(1436), Nrf2 activation : CK(177) : AC(86)
Additional Keywords : Andrographolide, Anti-Inflammatory Agents, Antioxidants : CK(1) : AC(1), stroke

This review discusses both the current knowledge of and new perspectives for honey therapy in ophthalmology.

Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Honey : CK(784) : AC(188)
Diseases : Eye Diseases : CK(1435) : AC(328), Wound Healing : CK(1013) : AC(337)
Pharmacological Actions : Anti-Bacterial Agents : CK(2088) : AC(821), Anti-Inflammatory Agents : CK(12461) : AC(4729)
Additional Keywords : Anti-Bacterial Agents, Anti-Inflammatory Agents, Eye Diseases, Honey : CK(1) : AC(1), wound healing

This study demonstrated that melatonin pretreatment attenuated lung ischaemia-reperfusion injury.

Article Published Date : Jan 14, 2018
Study Type : Animal Study
Additional Links
Substances : Melatonin : CK(1399) : AC(461)
Diseases : Ischemia : CK(76) : AC(38)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Interleukin-1 beta downregulation : CK(1743) : AC(868), NF-kappaB Inhibitor : CK(2446) : AC(1436), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(4357) : AC(1763)
Additional Keywords : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Ischemia, melatonin

Thymoquinone abolishes a number of factors known to be involved in rheumatoid arthritis pathogenesis.

Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(386) : AC(227)
Diseases : Inflammation : CK(6531) : AC(1986), Rheumatoid Arthritis : CK(1140) : AC(209)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Antiproliferative : CK(4773) : AC(3450), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645), Interleukin-1 beta downregulation : CK(1743) : AC(868), NF-kappaB Inhibitor : CK(2446) : AC(1436), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(4357) : AC(1763)
Additional Keywords : Anti-Inflammatory Agents, Antiproliferative : CK(65) : AC(52), Inflammation : CK(2) : AC(2), rheumatoid arthritis, thymoquinone

Thymoquinone may be considered for topical application alone in the treatment of acute otitis externa.

Article Published Date : Dec 13, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(386) : AC(227)
Diseases : Otitis : CK(10) : AC(1)
Pharmacological Actions : Anti-Bacterial Agents : CK(2088) : AC(821), Anti-Inflammatory Agents : CK(12461) : AC(4729)
Additional Keywords : Anti-Bacterial Agents, Anti-Inflammatory Agents, Otitis, Superiority of Natural Substances versus Drugs : CK(1538) : AC(312), thymoquinone

Treatment by Thymoquinone restores inflammation-induced liver fibrosis.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Thymoquinone : CK(386) : AC(227)
Diseases : Fibrosis: Liver : CK(22) : AC(8), Inflammation : CK(6531) : AC(1986), Lipopolysaccharide-Induced Toxicity : CK(1105) : AC(650)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729)
Additional Keywords : Anti-Inflammatory Agents, Fibrosis: Liver, Inflammation : CK(2) : AC(2), Lipopolysaccharide-Induced Toxicity, thymoquinone

Vitamin C is essential for preventing and improving insulin resistance.

Article Published Date : Apr 02, 2018
Study Type : Animal Study
Additional Links
Diseases : Insulin Disorders : CK(15) : AC(4), Vitamin C Deficiency : CK(96) : AC(22)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729)
Additional Keywords : Anti-Inflammatory Agents, Insulin Disorders, Vitamin C Deficiency

Vitamin D supplementation may have a beneficial role in ulcerative colitis patients.

Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D : CK(6193) : AC(833)
Diseases : C-Reactive Protein : CK(2693) : AC(263), Ulcerative Colitis : CK(485) : AC(124)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729)
Additional Keywords : Anti-Inflammatory Agents, C-Reactive Protein, Gene Expression Regulation : CK(431) : AC(214), Ulcerative Colitis, VITAMIN D

Vitamin K2 may be a potential therapeutic agent in the treatment of prostate cancer.

Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(383) : AC(50)
Diseases : Prostate Cancer : CK(2097) : AC(687)
Pharmacological Actions : Angiogenesis Inhibitors : CK(114) : AC(62), Anti-Inflammatory Agents : CK(12461) : AC(4729), Anti-metastatic : CK(1284) : AC(927), Apoptotic : CK(5217) : AC(3846), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2 : CK(1) : AC(1)

Walnut leaf extract exert protective effects against diabetic retinopathy.

Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Walnut : CK(491) : AC(107)
Diseases : Diabetic Retinopathy : CK(60) : AC(23)
Pharmacological Actions : Anti-Apoptotic : CK(1620) : AC(932), Anti-Inflammatory Agents : CK(12461) : AC(4729), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Diabetic Retinopathy, Walnut

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