Results for Liver Damage: Drug-Induced

Lycopene is a natural compound that was able to inhibit the production of ROS and mitigate the damage caused by acetaminophen.

Article Published Date : Jan 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carotenoids : CK(3269) : AC(832), Lycopene : CK(886) : AC(249)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Liver Damage: Drug-Induced : CK(316) : AC(124), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Antioxidants : CK(303) : AC(126), CAROTENOIDS, Hepatoprotective, Liver Damage: Drug-Induced, lycopene, Matrix metalloproteinase-2 (MMP-2) inhibitor, oxidative stress
Problem Substances : Acetaminophen, Paracetamol : CK(546) : AC(202)

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in mice.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(886) : AC(249)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(654) : AC(246), Liver Damage: Drug-Induced : CK(316) : AC(124)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hepatoprotective : CK(5098) : AC(2264), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(727) : AC(442)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Inflammatory Agents, Hepatoprotective, Liver Damage: Drug-Induced, lycopene
Problem Substances : Acetaminophen, Paracetamol : CK(546) : AC(202)

Protective effects of combined β-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity.

Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene : CK(2) : AC(1), Silymarin : CK(241) : AC(53)
Diseases : Liver Damage: Drug-Induced : CK(316) : AC(124)
Pharmacological Actions : Hepatoprotective : CK(5098) : AC(2264)
Additional Keywords : Beta-Caryophyllene, Hepatoprotective, Liver Damage: Drug-Induced, Plant Extracts : CK(14140) : AC(5210), SILYMARIN
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(2825) : AC(496)

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