Results for Liver Damage: Drug-Induced

Lycopene is a natural compound that was able to inhibit the production of ROS and mitigate the damage caused by acetaminophen.

Article Published Date : Jan 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carotenoids : CK(2398) : AC(554), Lycopene : CK(550) : AC(128)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(485) : AC(175), Liver Damage: Drug-Induced : CK(95) : AC(27), Oxidative Stress : CK(6519) : AC(2436)
Pharmacological Actions : Antioxidants : CK(14410) : AC(5758), Hepatoprotective : CK(3182) : AC(1418), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(551) : AC(315)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Antioxidants : CK(1) : AC(1), CAROTENOIDS, Hepatoprotective, Liver Damage: Drug-Induced, lycopene, Matrix metalloproteinase-2 (MMP-2) inhibitor, oxidative stress
Problem Substances : Acetaminophen : CK(204) : AC(68), Paracetamol : CK(121) : AC(36)

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in mice.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lycopene : CK(550) : AC(128)
Diseases : Acetaminophen (Tylenol) Toxicity : CK(485) : AC(175), Liver Damage: Drug-Induced : CK(95) : AC(27)
Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Hepatoprotective : CK(3182) : AC(1418), Interleukin-1 beta downregulation : CK(1743) : AC(868), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(551) : AC(315)
Additional Keywords : Acetaminophen (Tylenol) Toxicity, Anti-Inflammatory Agents, Hepatoprotective, Liver Damage: Drug-Induced, lycopene
Problem Substances : Acetaminophen : CK(204) : AC(68), Paracetamol : CK(121) : AC(36)

Protective effects of combined β-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity.

Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene : CK(2) : AC(1), Silymarin : CK(241) : AC(53)
Diseases : Liver Damage: Drug-Induced : CK(95) : AC(27)
Pharmacological Actions : Hepatoprotective : CK(3182) : AC(1418)
Additional Keywords : Beta-Caryophyllene, Hepatoprotective, Liver Damage: Drug-Induced, Plant Extracts : CK(11762) : AC(4236), SILYMARIN
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(2536) : AC(388)

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