Results for Shikonin

Inhibition of pyruvate kinase M2 markedly reduces chemoresistance of advanced bladder cancer to cisplatin.

Article Published Date : Apr 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Bladder Cancer : CK(521) : AC(176)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Chemosensitizer : CK(772) : AC(577)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, bladder cancer, Chemosensitizer, Chemotherapeutic Synergy: Cisplatin : CK(137) : AC(103), Dose Response : CK(1519) : AC(574), Shikonin

Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.

Article Published Date : Apr 10, 2017
Study Type : Human In Vitro
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Glioblastoma : CK(398) : AC(193)
Pharmacological Actions : Anti-metastatic : CK(1284) : AC(927), Antiproliferative : CK(4773) : AC(3450), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(551) : AC(315), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(543) : AC(337)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Chemotherapeutic Synergy: Temozolomide : CK(5) : AC(4), Glioblastoma, Shikonin

Shikonin attenuated hepatic ischemia/reperfusion injury by inhibiting apoptosis and autophagy.

Article Published Date : Mar 20, 2017
Study Type : Animal Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Liver Injury: Ischemia/reperfusion : CK(19) : AC(10)
Pharmacological Actions : Anti-Apoptotic : CK(1620) : AC(932), Autophagy Inhibitors : CK(26) : AC(13), Hepatoprotective : CK(3182) : AC(1418)
Additional Keywords : Anti-Apoptotic, Autophagy Inhibitors : CK(5) : AC(4), Hepatoprotective, Liver Injury: Ischemia/reperfusion, Shikonin

These results indicate that shikonin treatment may prevent the loss of vision associated with diabetic retinopathy.

Article Published Date : Mar 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Diabetic Retinopathy : CK(60) : AC(23)
Pharmacological Actions : Anti-Apoptotic : CK(1620) : AC(932), Anti-Inflammatory Agents : CK(12461) : AC(4729), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645)
Additional Keywords : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Diabetic Retinopathy, Shikonin

Connect with GreenMedInfo

MeWe

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.