Results for Cytotoxicity

Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells.

Article Published Date : Feb 29, 2004
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(3397) : AC(792)
Diseases : Liver Cancer : CK(1953) : AC(852)
Pharmacological Actions : Antioxidants : CK(14410) : AC(5758), Chemotherapeutic : CK(397) : AC(152), Cytotoxicity

Flavonoids showed a dose dependent cytotoxicity towards various types of leukemia cells in vitro.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Apigenin : CK(295) : AC(165), Baicalein : CK(106) : AC(75), Chrysin : CK(147) : AC(93), Flavonoids : CK(1616) : AC(523), Genistein : CK(650) : AC(296), Luteolin : CK(235) : AC(153), Naringenin : CK(241) : AC(139)
Diseases : Leukemia : CK(1284) : AC(586)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cytotoxicity
Additional Keywords : Dose Response : CK(1519) : AC(574)

kaempferol induced DNA damage and suppressed DNA repair and inhibited DNA repair associated protein expression in HL-60 cells

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Kaempferol : CK(102) : AC(65)
Diseases : Leukemia: Acute promyelocytic leukemia : CK(13) : AC(11)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Cytotoxicity, Tumor Suppressor Protein p53 Upregulation : CK(480) : AC(343)
Additional Keywords : Dose Response : CK(1519) : AC(574)

Metabolic profiling study of shikonin's cytotoxic activity in the Huh7 human hepatoma cell line.

Article Published Date : May 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Liver Cancer : CK(1953) : AC(852)
Pharmacological Actions : Cytotoxicity

Multiple myeloma tumor cells are selectively killed by pharmacologically-dosed ascorbic acid.

Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin C : CK(3397) : AC(792)
Diseases : Multiple Myeloma : CK(227) : AC(75), Smoldering multiple myeloma (SMM) : CK(20) : AC(2)
Pharmacological Actions : Cytotoxicity
Additional Keywords : Selective Cytotoxicity : CK(232) : AC(167)

Shikonin enhances NK cells proliferation and cytotoxicity.

Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Shikonin : CK(108) : AC(63)
Diseases : Colon Cancer : CK(1217) : AC(742)
Pharmacological Actions : Cytotoxicity, Immunomodulatory : CK(2249) : AC(733)

Thymol elicits HCT-116 colorectal carcinoma cell death through induction of oxidative stress.

Article Published Date : Mar 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(41) : AC(28)
Diseases : Colorectal Cancer : CK(2874) : AC(1192)
Pharmacological Actions : Cytotoxicity

Thymol induced Ca²⁺-dissociated cell death in prostate cancer.

Article Published Date : Jan 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Thymol : CK(41) : AC(28)
Diseases : Prostate Cancer : CK(2097) : AC(687)
Pharmacological Actions : Cytotoxicity

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