E-cadherin down-regulation

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8 Substances Researched for E-cadherin down-regulation

Name	AC	CK
Ginsenosides	1	2
4-Shogaol	1	1
Anthocyanins	1	1
Flavonoids	1	1
Grape	1	1
Nobiletin	1	1
Piperlongumine	1	1
Polyphenols	1	1

Research Articles 5
Cumulative Knowledge Score 8
Overall Research Rating GOOD

View the Evidence:
5 Abstracts with E-cadherin down-regulation Research

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Ginsenoside Rg3 inhibits epithelial-mesenchymal transition and invasion of lung cancer by down-regulating FUT4.Jan 11, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 Jan 12 ;7(2):1619-32. PMID: 26636541

Article Published Date : Jan 11, 2016

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Cancer Metastasis, Lung Cancer

Pharmacological Actions : Anti-metastatic, E-cadherin down-regulation

[+]

4-Shogaol, an active constituent of dietary ginger, inhibit human breast cancer cells. Jan 25, 2012

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Pubmed Data : J Agric Food Chem. 2012 Jan 25 ;60(3):852-61. Epub 2012 Jan 13. PMID: 22224671

Article Published Date : Jan 25, 2012

Study Type : In Vitro Study

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Substances : 4-Shogaol

Diseases : Breast Cancer, Breast Cancer: Metastatic

Pharmacological Actions : Anti-metastatic, E-cadherin down-regulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

A lyophilized grape extract comparable to putative dietary doses induced important morphology changes, migration inhibition, downregulation of undifferentiated stem/stem-like cells markers and EMT.Mar 31, 2015

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Pubmed Data : Nutr Cancer. 2015 Apr ;67(3):494-503. Epub 2015 Feb 23. PMID: 25705818

Article Published Date : Mar 31, 2015

Study Type : In Vitro Study

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Substances : Anthocyanins, Flavonoids, Grape, Polyphenols

Diseases : Colon Cancer

Pharmacological Actions : Anti-metastatic, Antioxidants, Antiproliferative , Cell cycle arrest, E-cadherin down-regulation, Nrf2 activation, P21 Activation, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Cancer Stem Cells, Dietary Doses, Plant Extracts

[+]

Downregulation of Notch-1 and reexpression of miR-200b by nobiletin might be a novel remedy for the therapy of lung cancer.Mar 31, 2015

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Pubmed Data : Pharmazie. 2015 Apr ;70(4):256-62. PMID: 26012256

Article Published Date : Mar 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Nobiletin

Diseases : Cancer Metastasis, Lung Cancer

Pharmacological Actions : Anti-metastatic, Antioxidants, Antiproliferative , E-cadherin down-regulation, MicroRNA modulator

[+]

Piperlongumine inhibits TGF-β-induced epithelial-to-mesenchymal transitionJul 18, 2017

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Pubmed Data : Eur J Pharmacol. 2017 Jul 19. Epub 2017 Jul 19. PMID: 28734931

Article Published Date : Jul 18, 2017

Study Type : In Vitro Study

Additional Links

Substances : Piperlongumine

Diseases : Cancers: All

Pharmacological Actions : Anti-metastatic, E-cadherin down-regulation

Research Articles 5
Cumulative Knowledge Score 8
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 5 Abstracts with E-cadherin down-regulation Research

Limited to Members Only

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Ginsenoside Rg3 inhibits epithelial-mesenchymal transition and invasion of lung cancer by down-regulating FUT4.Jan 11, 2016

Click here to read the entire abstract

4-Shogaol, an active constituent of dietary ginger, inhibit human breast cancer cells. Jan 25, 2012

Click here to read the entire abstract

A lyophilized grape extract comparable to putative dietary doses induced important morphology changes, migration inhibition, downregulation of undifferentiated stem/stem-like cells markers and EMT.Mar 31, 2015

Click here to read the entire abstract

Downregulation of Notch-1 and reexpression of miR-200b by nobiletin might be a novel remedy for the therapy of lung cancer.Mar 31, 2015

Click here to read the entire abstract

Piperlongumine inhibits TGF-β-induced epithelial-to-mesenchymal transitionJul 18, 2017

Click here to read the entire abstract

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E-cadherin down-regulation

View the Evidence:
5 Abstracts with E-cadherin down-regulation Research