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Neurotoxic
Views 8600
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Abstracts
Focused Research Topics
Focus Your Research
Click any topic below to filter + focus research
122 Problem Substances Researched for Neurotoxic
Name
AC
CK
Focus
Statin Drugs
40
191
Thimerosal
32
187
Gluten
18
141
Gliadin
10
100
Simvastatin
21
82
Fluoride
10
80
Wheat
10
72
Oseltamivir (trade name Tamiflu)
7
59
Mercury
11
56
Bisphenol A
22
54
Lovastatin
15
52
Lead
7
51
Arsenic
4
50
Aluminum
21
45
Glyphosate
21
42
Tamoxifen
3
40
Pesticides
9
38
Aluminum Hydroxide
5
25
Sodium Fluoride
9
24
Donepezil (trade name Aricept)
3
23
Pravastatin
3
23
Antipsychotic Drugs
2
22
Quetiapine
2
22
Rivastigmine
2
21
Amoxapine
1
20
Buproprione
1
20
Chlorprothiexene
1
20
Clozapine
1
20
Dental Amalgams
1
20
Escitaloprame
1
20
Fenofibrates
2
20
Maprotilene
1
20
Risperidone
1
20
Tobacco
2
20
Trimipramine
1
20
Aspartame
10
18
Atorvastatin
9
18
Monosodium Glutamate (MSG)
4
16
Tricresyl phosphates (TCPs)
5
15
Cholesterol Lowering Drugs
3
14
Organophosphates
2
12
Triclosan
2
12
Agricultural Chemicals
1
10
Aspirin
5
10
BisGMA-based dental products
1
10
Bupropion
1
10
Butyrophilin
1
10
Casein
1
10
Chlamydia Pneumoniae
1
10
Cow Milk
1
10
Energy Drinks
1
10
Industrial Copper (inorganic)
1
10
Industrial Iron
1
10
Iodine: Excess
1
10
Nicotine
1
10
Organochlorine pesticides
1
10
Parabens
1
10
Pepper Spray
1
10
Perfluorinated compounds
1
10
Perfluorooctane sulfonate (PFOS)
1
10
Polycyclic aromatic hydrocarbon: coal-fired power plant associated
1
10
Streptococcal M Protein
1
10
Tobacco Smoke: Passive
1
10
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
4
8
Herbicides
2
7
Paraquat
3
7
Infliximab
2
6
Brevetoxin
3
5
Chlorpyrifos
3
5
Red tide
3
5
Acetaminophen
2
4
Aluminum Chloride
2
4
Cadmium
2
4
Cipro
2
4
Flame Retardants
2
4
Paracetamol
2
4
Roundup (herbicide)
2
4
Sucralose (aka Splenda)
2
4
Sucrose
2
4
Antibiotics
1
3
Bisphenol S
2
3
Fusidic acid
1
3
Lamivudine
1
3
Rosuvastatin
1
3
Synthetic Cannabinoids
1
3
Acesulfame potassium
1
2
Aluminum oxide
1
2
Aromatase Inhibitor Drugs
1
2
Artificial Sweeteners
1
2
Cyclophosphamide
1
2
Deltamethrin
1
2
Dichlorvos
1
2
Doxorubicin
1
2
Endocrine Disrupting Chemicals (EDCs)
1
2
Fluoxetine (trade name Prozac)
1
2
Formaldehyde
1
2
Fructose
1
2
Glyphosate formulations
1
2
Memantine
1
2
Nanoparticles
1
2
Parathion
1
2
Selective Serotonin Reuptake Inhibitors (SSRIs)
1
2
Uranium: Depleted
1
2
Vaccine Adjuvants
1
2
Zinc Chloride
1
2
Alcohol Consumption
1
1
Benzo(a)pyrene
1
1
Brilliant Blue FCF
1
1
Chemotherapy
1
1
Cholinesterase Inhibitor Drugs
1
1
Dimethoate
1
1
Epstein-Barr Virus
1
1
Ethanol
1
1
Fluoroquinolone Antibiotic
1
1
Galantamine
1
1
Hormone Replacement Therapy
1
1
L-glutamic Acid
1
1
Mevastatin
1
1
Quinoline Yellow
1
1
Tylenol
1
1
Zinc Oxide
1
1
Zineb
1
1
201 Diseases Researched for Neurotoxic
Name
AC
CK
Focus
Statin-Induced Pathologies
44
187
Childhood Cognitive Disorders
10
140
Cognitive Decline/Dysfunction
15
124
Neurodevelopmental Disorders
15
114
Intelligence Quotient (IQ): Low/Impaired
8
110
Childhood Chemical Exposures
7
90
Celiac Disease
10
84
Gluten Sensitivity
9
83
Peripheral Neuropathies
10
79
Drug-Induced Toxicity
10
73
Autism Spectrum Disorders
10
68
Prenatal Nutrition: Learning/Intelligence of Offspring
7
68
Multiple Sclerosis
10
61
Tic Disorders
3
60
Autism
7
55
Neurodegenerative Diseases
22
54
Prenatal Chemical Exposures
13
54
Memory Disorders: Drug-Induced
4
50
Neuropathies
11
50
Psychiatric Disorders
7
50
Seizures
3
50
Mercury Poisoning
7
48
Alzheimer's Disease
11
47
Learning disorders
5
45
Amyotrophic Lateral Sclerosis
5
43
Vaccine-induced Toxicity
6
39
Neurotoxicity
18
37
Memory Disorders
9
36
Depression
4
32
Bisphenol Toxicity
14
30
Cerebellar Ataxia
3
30
Fluoride Toxicity
6
30
Schizophrenia
3
30
Pesticide Toxicity
12
28
Aluminum Toxicity
17
27
Brain Inflammation
5
26
Glyphosate Toxicity
13
25
Infant Neurological Development
4
24
Headache
3
23
Memory Loss
3
23
Migraine Disorders
3
23
Attention Deficit Hyperactivity Disorder
3
21
Aggression
2
20
Ataxia: Cerebellar
2
20
Attention Deficit Disorder
1
20
Brain Damage
8
20
Fluorosis
1
20
Infant Infections
1
20
Infantile Spasms
1
20
Influenza
1
20
Lead Poisoning
2
20
Lyell syndrome
1
20
Meningitis: Drug-Induced
1
20
Mental Retardation
1
20
Metabolic Diseases
1
20
Pneumonia: Drug-Induced
1
20
Smoking
2
20
Speech Disorders
1
20
Demyelinating Diseases
6
19
Oxidative Stress
9
18
Polyneuropathies
3
16
Aerotoxic Syndrome
5
15
Pregnancy: Psychological and Physical Distress.
3
14
Attention Deficit Disorder with Hyperactivity
3
13
Autoimmune Diseases
3
13
Brain: Oxidative Stress
7
13
Dementia
4
13
Psychological Well-Being
2
13
Brain: Microglial Activation
3
12
Chemotherapy-Induced Toxicity
2
12
Fetal Origin of Adult Disease
2
12
Gulf War Syndrome
2
12
Inflammation
2
12
Parkinson's Disease
8
12
Epilepsy
2
11
Suicidal Behavior
2
11
Anxiety Disorders
1
10
Arsenic Poisoning
1
10
Ataxia: Dominant
1
10
Ataxia: Sporadic
1
10
C-Reactive Protein
1
10
CNS White Matter Abnormalities
1
10
Carpal Tunnel Syndrome
1
10
Casein Intolerance
1
10
Cerebral Calcifications
1
10
Childhood Infections
1
10
Children: Impaired Growth
1
10
Coal-Fired Power Plant Associated Toxicity
1
10
Copper Toxicity
1
10
Cornea Damage
1
10
Developmental Disorder: Children
1
10
Epilepsy: With Cerebral Calcifications
1
10
Food Allergies
1
10
Gluten Ataxia
1
10
Headache: Migraine
1
10
Hearing Loss
5
10
Heavy Metal Toxicity
1
10
Hyperexcitable brain and refractory coeliac disease
1
10
Hypertension
1
10
Impotence
1
10
Impulse Control Disorders
1
10
Iron Poisoning
1
10
Migraines
1
10
Myofascial Pain Dysfunction Syndrome: Temporomandibular Joint
1
10
Neuropsychological Dysfunction: Psychomotor Speed
1
10
Nicotine/Tobacco Toxicity
1
10
Parkinsonian Disorders
5
10
Pesticide-Induced Toxicity: Organophosphates
1
10
Post-Traumatic Stress Disorders (PTSD)
1
10
Psychological Distress
1
10
Psychoses
1
10
Sensory Neuropathies
1
10
Sleep Disorders
1
10
Spinocerebellar Ataxia Type 2
1
10
Suicidal Ideation
1
10
TSH: Elevated
1
10
Lipid Peroxidation
5
9
Bisphenol-A Toxicity
4
8
Parkinsonism
4
8
Tinnitus
4
7
Birth Defects
2
6
Brain Injury: Hippocampal Damage
3
6
Encephalopathies
2
6
Mitochondrial Diseases
2
6
Abortion: Spontaneous
1
5
Acetaminophen (Tylenol) Toxicity
3
5
Ataxia
3
5
Diabetes Mellitus: Type 2
2
5
Excitotoxicity
3
5
Herbicide Toxicity
1
5
Red Tide Associated Toxicity
3
5
Delirium: Drug-Induced
2
4
Dopamine Levels: Low
2
4
Drug-Induced Nutrient Depletion: Statin Drugs
2
4
Hypothyroidism
2
4
Insulin Resistance
2
4
Neurologic Disorders
4
4
Substantia Nigra: Damage
2
4
Tremor
2
4
Aging
2
3
Blood-Brain-Barrier Disorders
2
3
Bulbar palsy
1
3
Cerebral Hypoperfusion
1
3
Encephalomyelitis
1
3
Guillain-Barre Syndrome
1
3
Hepatitis B
1
3
Melas Syndrome
1
3
Meningitis: Aseptic
1
3
Mood Disorders
1
3
Obesity
2
3
Rhabdomyolysis
1
3
Schizophrenic Disorders
1
3
Uveitis
1
3
Amyloidosis
1
2
Anxiety
1
2
Bee Colony Collapse
1
2
Brain Cancer
1
2
Brain: Vascular Congestion
1
2
Breast Cancer
1
2
Breast Cancer: Prevention
1
2
Chemotherapy-Induced Toxicity: Doxorubicin
1
2
DNA damage
2
2
Diabetes: Cognitive Dysfunction
1
2
Formaldehyde Toxicity
1
2
Fructose-Induced Toxicity
1
2
HPA Axis Dysregulation
1
2
Infant Chemical Exposures
1
2
Lipopolysaccharide-Induced Toxicity
1
2
Liver Damage: Drug-Induced
1
2
MSG Toxicity
1
2
Neurodegeneration: Dentate Gyrus
1
2
Neuromuscular Diseases
1
2
Obesity: Hypothalamic
1
2
Overweight
1
2
Testicular Diseases
1
2
Uranium Poisoning
1
2
Alcohol Toxicity
1
1
Amyotrophic lateral sclerosis (ALS)
1
1
Asthma
1
1
Ataxia: Idiopathic
1
1
Benzo[a]pyrene-induced Toxicity
1
1
Bronchitis
1
1
Cadmium Poisoning
1
1
Chemically-Induced Liver Damage
1
1
Chemotherapy-Induced Neurotoxicity
1
1
Cochlear Neuronal Damage
1
1
Depression
1
1
Dizziness
1
1
Endocannabinoid Disorders
1
1
Epstein-Barr Virus Infections
1
1
Gastrointestinal Complaints
1
1
Hallucinations
1
1
Hearing Disorders
1
1
Infertility
1
1
Macrophagic myofasciitis
1
1
Neuromyotoxicity
1
1
Neurotoxic Shellfish Poisoning
1
1
Parasuicide
1
1
Reye Syndrome
1
1
Skeletal Muscle Changes: Ultrastructural Changes
1
1
Stroke
1
1
Research Articles
323
Cumulative Knowledge Score
522
Overall Research Rating
GREAT
View the Evidence:
396 Abstracts with Neurotoxic Research
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[+]
As thimerosal was removed from childhood vaccines, the number of neurodevelopmental disorders decreased in the US.
Jun 01, 2006
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2006 Jun;12(6):CR231-9. Epub 2006 May 29. PMID:
16733480
Article Published Date
: Jun 01, 2006
Study Type
: Meta Analysis
Additional Links
Diseases
:
Childhood Chemical Exposures
,
Neurodevelopmental Disorders
,
Vaccine-induced Toxicity
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Children who live in a fluorosis area have 5 times higher odds of developing low IQ than those who live in a nonfluorosis area or a slight fluorosis area.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2008;126(1-3):115-20. Epub 2008 Aug 10. PMID:
18695947
Article Published Date
: Jan 01, 2008
Study Type
: Meta Analysis
Additional Links
Diseases
:
Childhood Cognitive Disorders
,
Cognitive Decline/Dysfunction
,
Intelligence Quotient (IQ): Low/Impaired
,
Prenatal Nutrition: Learning/Intelligence of Offspring
Problem Substances
:
Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Children who live in an arsenicosis area or a slight arsenicosis area have lower IQ than those who live in a non-arsenicosis area.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2009;129(1-3):88-93. Epub 2008 Dec 24. PMID:
19107329
Article Published Date
: Jan 01, 2009
Study Type
: Meta Analysis
Additional Links
Diseases
:
Childhood Cognitive Disorders
,
Intelligence Quotient (IQ): Low/Impaired
,
Prenatal Chemical Exposures
Problem Substances
:
Arsenic
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Dental amalgams (mercury exposure) increase the risk of multiple sclerosis.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Public Health Dent. 2007;67(1):64-6. PMID:
17436982
Article Published Date
: Jan 01, 2007
Study Type
: Meta Analysis
Additional Links
Diseases
:
Mercury Poisoning
,
Multiple Sclerosis
Additional Keywords
:
Diseases that are Linked
Problem Substances
:
Dental Amalgams
,
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Exposure to high levels of fluoride may adversely influence children's intelligence development.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Zhongguo Dang Dai Er Ke Za Zhi. 2008 Dec;10(6):723-5. PMID:
19102839
Article Published Date
: Dec 01, 2008
Study Type
: Meta Analysis
Additional Links
Diseases
:
Childhood Cognitive Disorders
,
Cognitive Decline/Dysfunction
,
Fluoride Toxicity
,
Fluorosis
,
Intelligence Quotient (IQ): Low/Impaired
,
Prenatal Nutrition: Learning/Intelligence of Offspring
Problem Substances
:
Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Exposure to mercury from thimerosal-containing vaccines was associcated with an increased risk of neurodevelopmental problems in infants from 1992-1997.
Apr 01, 2005
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2005 Apr;11(4):CR160-70. Epub 2005 Mar 24. PMID:
15795695
Article Published Date
: Apr 01, 2005
Study Type
: Meta Analysis
Additional Links
Diseases
:
Attention Deficit Disorder
,
Learning disorders
,
Neurodevelopmental Disorders
,
Seizures
,
Speech Disorders
,
Tic Disorders
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Oseltamivir for treatment of influenza in infants less than one year results in complications in 54% of the patients with the most serious of which were meningitis in 1 infant (1%), pneumonia in 9 (6%), and otitis media in 2 (1%)
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Pediatr Infect Dis J. 2010 Jun;29(6):495-8. PMID:
20035245
Article Published Date
: Jun 01, 2010
Study Type
: Meta Analysis
Additional Links
Diseases
:
Drug-Induced Toxicity
,
Infant Infections
,
Influenza
,
Meningitis: Drug-Induced
,
Pneumonia: Drug-Induced
Additional Keywords
:
Iatrogenic Disease
Problem Substances
:
Oseltamivir (trade name Tamiflu)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Oseltamivir has been reported to cause neuropsychiatric disorders in children and may be particularly dangerous to infants.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Prescrire Int. 2006 Oct;15(85):182-3. PMID:
17128526
Article Published Date
: Oct 01, 2006
Study Type
: Meta Analysis
Additional Links
Diseases
:
Childhood Chemical Exposures
,
Childhood Cognitive Disorders
,
Lyell syndrome
,
Psychiatric Disorders
Problem Substances
:
Oseltamivir (trade name Tamiflu)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Prenatal stress inhibits neuronal maturation in offspring.
Aug 10, 2011
Click here to read the entire abstract
Pubmed Data
: J Neurosci. 2011 Aug 10 ;31(32):11505-14. PMID:
21832180
Article Published Date
: Aug 10, 2011
Study Type
: Meta Analysis
Additional Links
Diseases
:
Prenatal Nutrition: Learning/Intelligence of Offspring
Anti Therapeutic Actions
:
Prenatal Stress
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Rates of autism, speech disorders, mental retardation, infantile spasms, and thinking abnormalities were higher in children exposured to higher thimerosal levels.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Toxicol Environ Health A. 2006 Aug;69(15):1481-95. PMID:
16766480
Article Published Date
: Aug 01, 2006
Study Type
: Meta Analysis
Additional Links
Diseases
:
Autism
,
Cognitive Decline/Dysfunction
,
Infantile Spasms
,
Mental Retardation
,
Neurodevelopmental Disorders
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Tamoxifen interferes with cognitive function in breast cancer patients.
Nov 01, 2000
Click here to read the entire abstract
Pubmed Data
: Breast Cancer Res Treat. 2000 Nov;64(2):165-76. PMID:
11194452
Article Published Date
: Nov 01, 2000
Study Type
: Meta Analysis
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Drug-Induced Toxicity
,
Memory Disorders: Drug-Induced
Additional Keywords
:
Drug: Tamoxifen
Problem Substances
:
Tamoxifen
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The WHO reports 71,471 seizures from a variety of neuroactive drugs between 1968-2006.
Mar 01, 2010
Click here to read the entire abstract
Pubmed Data
: Seizure. 2010 Mar;19(2):69-73. Epub 2009 Dec 24. PMID:
20036167
Article Published Date
: Mar 01, 2010
Study Type
: Meta Analysis
Additional Links
Diseases
:
Seizures
Problem Substances
:
Amoxapine
,
Buproprione
,
Chlorprothiexene
,
Clozapine
,
Donepezil (trade name Aricept)
,
Escitaloprame
,
Maprotilene
,
Quetiapine
,
Rivastigmine
,
Trimipramine
Adverse Pharmacological Actions
:
Neurotoxic
[+]
There is good evidence to support the existence of both metabolic and neurological adverse effects in children treated with second-generation antipsychotics.
Jul 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Saf. 2011 Aug 1 ;34(8):651-68. PMID:
21751826
Article Published Date
: Jul 31, 2011
Study Type
: Meta Analysis, Review
Additional Links
Diseases
:
Metabolic Diseases
Additional Keywords
:
Increased Risk
Problem Substances
:
Antipsychotic Drugs
,
Risperidone
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Thimersol exposure in infants is associated with an increase risk for tics.
Sep 01, 2004
Click here to read the entire abstract
Pubmed Data
: Pediatrics. 2004 Sep;114(3):584-91. PMID:
15342825
Article Published Date
: Sep 01, 2004
Study Type
: Meta Analysis
Additional Links
Diseases
:
Tic Disorders
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Thimersol exposure is associated with tics and delayed language acquisition in infants.
Nov 01, 2003
Click here to read the entire abstract
Pubmed Data
: Pediatrics. 2003 Nov;112(5):1039-48. PMID:
14595043
Article Published Date
: Nov 01, 2003
Study Type
: Meta Analysis
Additional Links
Diseases
:
Learning disorders
,
Neurodevelopmental Disorders
,
Tic Disorders
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
A high prevalence of gluten sensitivity is found in sporadic and hereditary cerebellar ataxia.
Apr 01, 2001
Click here to read the entire abstract
Pubmed Data
: Ann Neurol. 2001 Apr;49(4):540-3. PMID:
11310636
Article Published Date
: Apr 01, 2001
Study Type
: Human Study
Additional Links
Diseases
:
Ataxia: Cerebellar
,
Food Allergies
,
Gluten Sensitivity
Problem Substances
:
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration.
Nov 01, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inorg Biochem. 2009 Nov;103(11):1555-62. Epub 2009 Aug 20. PMID:
19740540
Article Published Date
: Nov 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Gulf War Syndrome
Additional Keywords
:
Adjuvant Toxicity
Problem Substances
:
Aluminum Hydroxide
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aluminum vaccine adjuvants appear to contribute to the rising prevalence of autism.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Inorg Biochem. 2011 Nov ;105(11):1489-99. Epub 2011 Aug 23. PMID:
22099159
Article Published Date
: Nov 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
Anti Therapeutic Actions
:
Vaccination: All
Problem Substances
:
Aluminum Hydroxide
Adverse Pharmacological Actions
:
Immunotoxic
,
Neurotoxic
[+]
Antigliadin antibodies are found at a higher prevalence in Cuban patients with spinocerebellar ataxia type 2.
Mar 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Neurol Neurosurg Psychiatry. 2008 Mar ;79(3):315-7. Epub 2007 Oct 19. PMID:
17951282
Article Published Date
: Mar 01, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Spinocerebellar Ataxia Type 2
Additional Keywords
:
Anti-Gliadin Antibodies
Problem Substances
:
Gliadin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Celiac disease is associated with ataxic syndromes without definite diagnosis, suggesting that it plays a part in the pathogenesis of some ataxic syndromes.
Jan 01, 1999
Click here to read the entire abstract
Pubmed Data
: J Neurol Neurosurg Psychiatry. 1999 Jan ;66(1):32-5. PMID:
9886447
Article Published Date
: Jan 01, 1999
Study Type
: Human Study
Additional Links
Diseases
:
Ataxia: Cerebellar
,
Celiac Disease
Problem Substances
:
Gliadin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Children's growth and intelligence can be adversely affected by fluoride and arsenic exposure in drinking water.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Environ Health Perspect. 2007 Apr;115(4):643-7. Epub 2007 Jan 9. PMID:
17450237
Article Published Date
: Apr 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Childhood Chemical Exposures
,
Childhood Cognitive Disorders
,
Children: Impaired Growth
,
Intelligence Quotient (IQ): Low/Impaired
Problem Substances
:
Arsenic
,
Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Chronic consumption of proton pump inhibitors may increase the risk for Alzheimer disease.
Apr 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Clin Pharm Ther. 2010 Apr;35(2):125-6. PMID:
20456731
Article Published Date
: Apr 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain: Microglial Activation
,
Neurodegenerative Diseases
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Cigarette smoking is associated with increased risk for ALS.
Jan 01, 1999
Click here to read the entire abstract
Pubmed Data
: Neuroepidemiology. 1999;18(4):194-202. PMID:
10364720
Article Published Date
: Jan 01, 1999
Study Type
: Human Study
Additional Links
Diseases
:
Amyotrophic Lateral Sclerosis
,
Smoking
Problem Substances
:
Tobacco
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Circulating levels of autophagy markers were low in children with higher fluoride body burden and lower intelligence quotient scores.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2019 Sep 1 ;378:114608. Epub 2019 Jun 5. PMID:
31173788
Article Published Date
: Aug 31, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Fluoride Toxicity
Problem Substances
:
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Cognitive impairment and associated loss in brain white microstructure in aircrew members exposed to engine oil fumes.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Brain Imaging Behav. 2016 Jun ;10(2):437-44. PMID:
26063438
Article Published Date
: May 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Aerotoxic Syndrome
,
Brain Damage
,
Depression
Anti Therapeutic Actions
:
Air Travel
Problem Substances
:
Tricresyl phosphates (TCPs)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Decreased brain volume in adults with childhood lead exposure.
May 26, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS Med. 2008 May 27 ;5(5):e112. PMID:
18507499
Article Published Date
: May 26, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Childhood Chemical Exposures
,
Childhood Cognitive Disorders
,
Lead Poisoning
,
Neurodegenerative Diseases
Problem Substances
:
Lead
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Disaster-related prenatal maternal stress influences birth outcomes, including lower head circumference.
Jul 22, 2011
Click here to read the entire abstract
Pubmed Data
: Early Hum Dev. 2011 Jul 22. Epub 2011 Jul 22. PMID:
21784587
Article Published Date
: Jul 22, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Infant Neurological Development
,
Post-Traumatic Stress Disorders (PTSD)
,
Pregnancy: Psychological and Physical Distress.
Anti Therapeutic Actions
:
Prenatal Stress
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Epilepsy with cerebral calcifications of unexplained origin may likely be caused by undiagnosed celiac disease.
Aug 22, 1992
Click here to read the entire abstract
Pubmed Data
: Lancet. 1992 Aug 22;340(8817):439-43. PMID:
1354781
Article Published Date
: Aug 22, 1992
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
,
Cerebral Calcifications
,
Epilepsy
,
Epilepsy: With Cerebral Calcifications
Additional Keywords
:
Diseases that are Linked
Problem Substances
:
Gluten
,
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Exposure of pregnant women to emissions of PAHs from the coal-burning plant, in combination with prenatal exposure to envrionmental tobacco smoke, may have adversely affected cognitive function of children at age 5.
Mar 01, 2012
Click here to read the entire abstract
Pubmed Data
: Environ Res. 2012 Mar 1. Epub 2012 Mar 1. PMID:
22386727
Article Published Date
: Mar 01, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Coal-Fired Power Plant Associated Toxicity
,
Intelligence Quotient (IQ): Low/Impaired
,
Prenatal Chemical Exposures
Problem Substances
:
Polycyclic aromatic hydrocarbon: coal-fired power plant associated
,
Tobacco Smoke: Passive
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Exposure to fluoride and arsenic in drinking water is associated with decreased intelligence in children.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cad Saude Publica. 2007;23 Suppl 4:S579-87. PMID:
18038039
Article Published Date
: Jan 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Childhood Chemical Exposures
,
Childhood Cognitive Disorders
,
Intelligence Quotient (IQ): Low/Impaired
Problem Substances
:
Arsenic
,
Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Food allergies and migraine.
Dec 31, 1969
Click here to read the entire abstract
Pubmed Data
: Lancet. 1979 May 5 ;1(8123):966-9. PMID:
87628
Study Type
: Human Study
Additional Links
Diseases
:
Migraine Disorders
Therapeutic Actions
:
Dietary Modification: Elimination Diet
Problem Substances
:
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Gluten sensitivity is a clinically confirmed problem in multiple sclerosis.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Ann N Y Acad Sci. 2009 Sep;1173:343-9. PMID:
19758171
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Gluten Sensitivity
,
Multiple Sclerosis
Problem Substances
:
Gliadin
,
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Gluten sensitivity is associated with sporadic cerebellar ataxia in Taiwan.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Acta Neurol Taiwan. 2010 Dec;19(4):263-9. PMID:
21210327
Article Published Date
: Dec 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Cerebellar Ataxia
Problem Substances
:
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Greater exposure to bisGMA-based (BPA-containing) dental composite restorations was associated with impaired psychosocial function in children.
Jul 15, 2012
Click here to read the entire abstract
Pubmed Data
: Pediatrics. 2012 Jul 16. Epub 2012 Jul 16. PMID:
22802599
Article Published Date
: Jul 15, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Childhood Cognitive Disorders
Anti Therapeutic Actions
:
Dental Fillings: Bisphenol A-based
Problem Substances
:
BisGMA-based dental products
,
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Headache and CNS white matter abnormalities may be associated with gluten sensitivity.
Feb 13, 2001
Click here to read the entire abstract
Pubmed Data
: Neurology. 2001 Feb 13 ;56(3):385-8. PMID:
11171906
Article Published Date
: Feb 13, 2001
Study Type
: Human Study
Additional Links
Diseases
:
CNS White Matter Abnormalities
,
Headache
Problem Substances
:
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Headache and mechanical sensitization of human pericranial muscles after repeated intake of monosodium glutamate (MSG).
Nov 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Headache Pain. 2013 Dec ;14(1):2. Epub 2013 Jan 24. PMID:
23565943
Article Published Date
: Nov 30, 2013
Study Type
: Human Study
Additional Links
Diseases
:
Headache
,
Headache: Migraine
,
Hypertension
,
Migraines
,
Myofascial Pain Dysfunction Syndrome: Temporomandibular Joint
Problem Substances
:
Monosodium Glutamate (MSG)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Heavy metal accumulation and associated biochemical alterations are found in Autistic Spectrum Disorder.
Jul 14, 2011
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2011 Jul 14. Epub 2011 Jul 14. PMID:
21755304
Article Published Date
: Jul 14, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Arsenic Poisoning
,
Autism Spectrum Disorders
,
Copper Toxicity
,
Heavy Metal Toxicity
,
Iron Poisoning
,
Mercury Poisoning
Additional Keywords
:
Diseases that are Linked
Problem Substances
:
Arsenic
,
Industrial Copper (inorganic)
,
Industrial Iron
,
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
High exposure to ethylmercury from thimerosal-containing vaccines in the first month of life increases the risk of subsequent development of neurologic development impairment.
Dec 31, 1969
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: NONE
Study Type
: Human Study
Additional Links
Diseases
:
Autism Spectrum Disorders
,
Infant Neurological Development
Anti Therapeutic Actions
:
Vaccination: All
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
High iodine and high fluorine adversely effects the intelligence and health of children.
Oct 01, 1994
Click here to read the entire abstract
Pubmed Data
: Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Oct;15(5):296-8. PMID:
7859263
Article Published Date
: Oct 01, 1994
Study Type
: Human Study
Additional Links
Diseases
:
Childhood Chemical Exposures
,
Childhood Cognitive Disorders
,
Intelligence Quotient (IQ): Low/Impaired
,
TSH: Elevated
Problem Substances
:
Fluoride
,
Iodine: Excess
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Highly significant increases compared with controls were found in patients with multiple sclerosis for IgA and IgG antibodies against gliadin and gluten and IgA antibodies against casein.
Oct 01, 2004
Click here to read the entire abstract
Pubmed Data
: Acta Neurol Scand. 2004 Oct;110(4):239-41. PMID:
15355487
Article Published Date
: Oct 01, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Casein Intolerance
,
Gluten Sensitivity
,
Multiple Sclerosis
Problem Substances
:
Casein
,
Gliadin
,
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Hospitalized patients with overdoses of Wellbutrin XL were studied for agitation, tremors, hallucinations, and seizures with delayed seizure onset noted.
Sep 30, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Emerg Med. 2009 Oct ;27(8):911-5. PMID:
19857406
Article Published Date
: Sep 30, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Seizures
Problem Substances
:
Bupropion
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Hyperexcitable brain and refractory coeliac disease: a new syndrome.
Oct 31, 2013
Click here to read the entire abstract
Article Published Date
: Oct 31, 2013
Study Type
: Human Study
Additional Links
Diseases
:
Gluten Ataxia
,
Hyperexcitable brain and refractory coeliac disease
Pharmacological Actions
:
Neurotransmitter Uptake Inhibitors
Problem Substances
:
Gluten
,
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Individuals with schizophrenia have a novel immune response to gluten.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Schizophr Res. 2010 May;118(1-3):248-55. Epub 2009 Sep 11. PMID:
19748229
Article Published Date
: May 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
,
Schizophrenia
Additional Keywords
:
Diseases that are Linked
Problem Substances
:
Gliadin
,
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Lead and mercury negatively affect infant milestones like walking and talking.
Apr 01, 2014
Click here to read the entire abstract
Pubmed Data
: Environ Pollut. 2014 Apr ;187:130-5. Epub 2014 Jan 28. PMID:
24486466
Article Published Date
: Apr 01, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Mercury Poisoning
Additional Keywords
:
breastfeeding
,
Infant Body Burden
,
infant health
Problem Substances
:
Aluminum
,
Lead
,
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Lead exposure at younger age significantly impacts a child's later neurodevelopment.
Aug 09, 2011
Click here to read the entire abstract
Pubmed Data
: Biomarkers. 2011 Aug 9. Epub 2011 Aug 9. PMID:
21827276
Article Published Date
: Aug 09, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Childhood Chemical Exposures
,
Childhood Cognitive Disorders
,
Intelligence Quotient (IQ): Low/Impaired
Problem Substances
:
Lead
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Lead may contribute to the pathogenesis of autism.
Jul 06, 2011
Click here to read the entire abstract
Pubmed Data
: Clin Biochem. 2011 Jul 6. Epub 2011 Jul 6. PMID:
21763301
Article Published Date
: Jul 06, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
,
Lead Poisoning
Problem Substances
:
Lead
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Lipid lowering drugs increase the risk of peripheral neuropathy.
Dec 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Epidemiol Community Health. 2004 Dec ;58(12):1047-51. PMID:
15547071
Article Published Date
: Dec 01, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Peripheral Neuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Cholesterol Lowering Drugs
,
Fenofibrates
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Long-term exposure to statin drugs may substantially increase the risk of polyneuropathy.
May 14, 2002
Click here to read the entire abstract
Pubmed Data
: Neurology. 2002 May 14 ;58(9):1333-7. PMID:
12011277
Article Published Date
: May 14, 2002
Study Type
: Human Study
Additional Links
Diseases
:
Polyneuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Lovastatin
,
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Long-term treatment with statins caused a clinically silent but still definite damage to peripheral nerves when the treatment lasts longer than 2 years.
Sep 03, 2011
Click here to read the entire abstract
Pubmed Data
: Neuro Endocrinol Lett. 2011 Sep 3 ;32(5):688-690. Epub 2011 Sep 3. PMID:
22167150
Article Published Date
: Sep 03, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Peripheral Neuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Long-term treatment with statins might cause a clinically silent but still electrophysiologically definite damage to peripheral nerves.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2007 Dec ;151(2):307-10. PMID:
18345269
Article Published Date
: Dec 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Peripheral Neuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Lovastatin may adversely affect neuropsychological tests of attention and psychomotor speed.
May 01, 2000
Click here to read the entire abstract
Pubmed Data
: Am J Med. 2000 May ;108(7):538-46. PMID:
10806282
Article Published Date
: May 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Neuropsychological Dysfunction: Psychomotor Speed
,
Psychological Well-Being
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Markers of gluten sensitivity and celiac disease are increased in recent-onset psychosis and multi-episode schizophrenia.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Biol Psychiatry. 2010 Jul 1;68(1):100-4. Epub 2010 May 14. PMID:
20471632
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
,
Gluten Sensitivity
,
Psychoses
,
Schizophrenia
Problem Substances
:
Gliadin
,
Gluten
,
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Memory deficits occur in breast cancer patients who receive either chemotherapy or tamoxifen.
Sep 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Psychosoc Oncol. 2011 Sep-Oct;29(5):499-514. PMID:
21882931
Article Published Date
: Sep 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity
,
Memory Disorders: Drug-Induced
,
Memory Loss
Anti Therapeutic Actions
:
Chemotherapy
Problem Substances
:
Tamoxifen
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Mercury and elevated testosterone in autistic children may work synergistically and more studies should be conducted to understand the relationship.
Jan 01, 2005
Click here to read the entire abstract
Pubmed Data
: Med Hypotheses. 2005 ;64(5):946-54. PMID:
15780490
Article Published Date
: Jan 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Testosterone
Diseases
:
Autism
,
Autism Spectrum Disorders
Additional Keywords
:
Heavy Metals and Autism
,
Vaccine Research
Problem Substances
:
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Mercury exposure from thimerosal containing childhood vaccines raised the subsequent risk of diagnosis of emotional disturbances.
Jan 18, 2017
Click here to read the entire abstract
Pubmed Data
: Brain Inj. 2017 Jan 19:1-7. Epub 2017 Jan 19. PMID:
28102704
Article Published Date
: Jan 18, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Mercury Poisoning
Additional Keywords
:
Increased Risk
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Mercury levels are 1.9 times higher in subjects diagnosed with autism spectrum disorders.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Acta Neurobiol Exp (Wars). 2010;70(2):177-86. PMID:
20628441
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
Problem Substances
:
Mercury
,
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Milk and bacterial proteins may produce neuron-specific antigens in children with autism.
Aug 01, 2002
Click here to read the entire abstract
Pubmed Data
: J Neuroimmunol. 2002 Aug;129(1-2):168-77. PMID:
12161033
Article Published Date
: Aug 01, 2002
Study Type
: Human Study
Additional Links
Diseases
:
Autism Spectrum Disorders
,
Autoimmune Diseases
,
Brain Inflammation
Additional Keywords
:
Molecular Mimicry
Problem Substances
:
Butyrophilin
,
Chlamydia Pneumoniae
,
Cow Milk
,
Streptococcal M Protein
Adverse Pharmacological Actions
:
Immunoreactive
,
Immunotoxic
,
Neurotoxic
[+]
Neurological symptoms occur in 6-10% of those with celiac disease, with cerebella ataxia being the most frequent symptom.
Dec 15, 2009
Click here to read the entire abstract
Pubmed Data
: Mov Disord. 2009 Dec 15;24(16):2358-62. PMID:
19845007
Article Published Date
: Dec 15, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Carpal Tunnel Syndrome
,
Celiac Disease
,
Cerebellar Ataxia
,
Gluten Sensitivity
,
Migraine Disorders
,
Psychiatric Disorders
Additional Keywords
:
Diseases that are Linked
Problem Substances
:
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Occupational exposures to agricultural chemicals is associated with increased risk for ALS.
Jun 15, 1997
Click here to read the entire abstract
Pubmed Data
: Am J Epidemiol. 1997 Jun 15;145(12):1076-88. PMID:
9199537
Article Published Date
: Jun 15, 1997
Study Type
: Human Study
Additional Links
Diseases
:
Amyotrophic Lateral Sclerosis
Problem Substances
:
Agricultural Chemicals
,
Pesticides
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Organic-Hg exposure from thimerosal-containing hepatitis B vaccine led to an increased risk of neurodevelopmental disorder diagnosis.
Aug 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2014 Sep ;11(9):9156-70. Epub 2014 Sep 5. PMID:
25198681
Article Published Date
: Aug 31, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Attention Deficit Disorder with Hyperactivity
,
Neurodevelopmental Disorders
Additional Keywords
:
Increased Risk
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Pepper spray may result in damage to corneal nerve terminals with physical symptoms that last at least a week.
Jul 01, 2000
Click here to read the entire abstract
Pubmed Data
: Invest Ophthalmol Vis Sci. 2000 Jul ;41(8):2138-47. PMID:
10892855
Article Published Date
: Jul 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Cornea Damage
Pharmacological Actions
:
Neuritogenic
Additional Keywords
:
Plant Extracts
Anti Therapeutic Actions
:
Pepper Spraying
Problem Substances
:
Pepper Spray
Adverse Pharmacological Actions
:
Cytotoxic
,
Neurotoxic
[+]
Perfluorinated compound exposure in children has been linked to impulse control problems.
Jun 17, 2011
Click here to read the entire abstract
Pubmed Data
: Environ Sci Technol. 2011 Jun 17. Epub 2011 Jun 17. PMID:
21682250
Article Published Date
: Jun 17, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Attention Deficit Hyperactivity Disorder
,
Impulse Control Disorders
Problem Substances
:
Perfluorinated compounds
,
Perfluorooctane sulfonate (PFOS)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Persons with schizophrenia have higher than expected titers of antibodies related to celiac disease and gluten sensitivity.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Schizophr Bull. 2011 Jan;37(1):94-100. Epub 2009 Jun 3. PMID:
19494248
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Gluten Sensitivity
,
Schizophrenia
Additional Keywords
:
Diseases that are Linked
Problem Substances
:
Gluten
,
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Pesticide exposure is associated with an increased risk of amyotrophic lateral sclerosis.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Ann Ist Super Sanita. 2010;46(3):284-7. PMID:
20847462
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Amyotrophic Lateral Sclerosis
Problem Substances
:
Pesticides
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Pesticide exposure is associated with psychological distress and suicidal ideation.
Nov 01, 2010
Click here to read the entire abstract
Pubmed Data
: Occup Environ Med. 2010 Nov;67(11):778-84. Epub 2010 Aug 25. PMID:
20798019
Article Published Date
: Nov 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Pesticide-Induced Toxicity: Organophosphates
,
Pesticide Toxicity
,
Psychological Distress
,
Suicidal Behavior
,
Suicidal Ideation
Problem Substances
:
Organochlorine pesticides
,
Organophosphates
,
Pesticides
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Porphyrin patterns in autism may indicate mercury toxicity. The authors emphasize that additional research should be conducted to explore the role of mercury in autism.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2006 Aug ;10(1):57-64. PMID:
17000470
Article Published Date
: Aug 01, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
Additional Keywords
:
Heavy Metals and Autism
,
Vaccine Research
Problem Substances
:
Mercury
Adverse Pharmacological Actions
:
Inflammatory
,
Neurotoxic
[+]
Psychiatric adverse reactions associated with cholesterol-lowering drugs have been reported.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Drug Saf. 2007 ;30(3):195-201. PMID:
17343428
Article Published Date
: Jan 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Aggression
,
Depression
,
Memory Disorders: Drug-Induced
,
Psychiatric Disorders
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Fenofibrates
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Sensory ganglionopathy may be a manifestation of gluten sensitivity.
Sep 14, 2010
Click here to read the entire abstract
Pubmed Data
: Neurology. 2010 Sep 14;75(11):1003-8. PMID:
20837968
Article Published Date
: Sep 14, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
,
Gluten Sensitivity
,
Peripheral Neuropathies
,
Sensory Neuropathies
Problem Substances
:
Gliadin
,
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Severity of autism may correlated with the number of maternal dental amalgams.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Acta Neurobiol Exp (Wars). 2009 ;69(2):189-97. PMID:
19593333
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
,
Birth Defects
Additional Keywords
:
Heavy Metals and Autism
,
Pregnancy
,
Pregnancy And Fetal Growth
Problem Substances
:
Dental Amalgams
,
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Simvastatin inhibits brain cholesterol biosynthesis without positively alterting molecular indices of Alzheimer disease pathology.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Alzheimer Dis Assoc Disord. 2010 Jul-Sep;24(3):220-6. PMID:
20473136
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin drug use results in decrements in cognitive functioning.
Dec 01, 2004
Click here to read the entire abstract
Pubmed Data
: Am J Med. 2004 Dec 1 ;117(11):823-9. PMID:
15589485
Article Published Date
: Dec 01, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Statin-Induced Pathologies
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin drugs are associated with adverse mental effects.
Sep 20, 1997
Click here to read the entire abstract
Pubmed Data
: Tidsskr Nor Laegeforen. 1997 Sep 20 ;117(22):3210-3. PMID:
9411859
Article Published Date
: Sep 20, 1997
Study Type
: Human Study
Additional Links
Diseases
:
Aggression
,
Anxiety Disorders
,
Depression
,
Impotence
,
Sleep Disorders
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin drugs have been linked to neurotoxicity.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Neth J Med. 2006 Oct ;64(9):334-8. PMID:
17057271
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Neuropathies
,
Neurotoxicity
,
Peripheral Neuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin drugs show no cognitive or anti-amyloid benefits and may be associated with cognitive impairment.
Jul 01, 2003
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2003 Jul ;23(7):871-80. PMID:
12885101
Article Published Date
: Jul 01, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Memory Disorders
Problem Substances
:
Lovastatin
,
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin use is associated with with neuropathy.
Feb 01, 2003
Click here to read the entire abstract
Pubmed Data
: Ann Pharmacother. 2003 Feb ;37(2):274-8. PMID:
12549960
Article Published Date
: Feb 01, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Neuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin-associated adverse cognitive effects have been reported with 90% resolving after drug discontinuation.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2009 Jul ;29(7):800-11. PMID:
19558254
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
,
Memory Disorders
,
Memory Loss
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin-associated peripheral neuropathy has been recorded in the biomedical literature.
Sep 01, 2004
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2004 Sep ;24(9):1194-203. PMID:
15460180
Article Published Date
: Sep 01, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Peripheral Neuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Subclinical pertussis infection, which results from the vaccine's failure to produce mucosal immunity and prevent infection and transmission, is believed to be a direct cause of MS via impaired immunity to pertussis, which is a neurotoxin.
Apr 01, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Immunobiology. 2016 Apr ;221(4):512-5. Epub 2015 Dec 18. PMID:
26724970
Article Published Date
: Apr 01, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Multiple Sclerosis
Additional Keywords
:
Vaccine Research
Anti Therapeutic Actions
:
Vaccination: Diphtheria-Pertussis-Tetanus
Adverse Pharmacological Actions
:
Immunotoxic
,
Neurotoxic
[+]
Tamoxifen treatment results in adverse structural and functional changes in the brain in women.
Jan 01, 2004
Click here to read the entire abstract
Pubmed Data
: Neuroimage. 2004 Jan;21(1):364-71. PMID:
14741674
Article Published Date
: Jan 01, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Drug-Induced Toxicity
,
Memory Disorders: Drug-Induced
Additional Keywords
:
Drug: Tamoxifen
Problem Substances
:
Tamoxifen
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The combination of Red Bull and mental stress impose a cumulative cardiovascular load and reduces cerebral blood flow.
Jan 14, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Cardiol. 2015 Jan 15 ;115(2):183-9. Epub 2014 Oct 29. PMID:
25465941
Article Published Date
: Jan 14, 2015
Study Type
: Human Study
Additional Links
Additional Keywords
:
Risk Factors
Problem Substances
:
Energy Drinks
Adverse Pharmacological Actions
:
Cardiotoxic
,
Neurotoxic
[+]
The median dentate nucleus maximum standardized uptake value was significantly lower in the subject group than in the control group.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nucl Med Technol. 2017 03 ;45(1):30-33. Epub 2016 Nov 10. PMID:
27834725
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Gadolinium Toxicity
Problem Substances
:
Gadolinium
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The prevalence of peripheral neuropathy is significantly higher among those who used statins.
Oct 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Diabetes. 2012 Nov 1. Epub 2012 Nov 1. PMID:
23121724
Article Published Date
: Oct 31, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Peripheral Neuropathies
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The prophylactic use of oseltamivir in children results in side effects including high rates of gastrointestinal and neuropsychiatric reactions.
Jul 30, 2009
Click here to read the entire abstract
Pubmed Data
: Euro Surveill. 2009 Jul 30;14(30):19287. Epub 2009 Jul 30. PMID:
19643062
Article Published Date
: Jul 30, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Childhood Infections
,
Drug-Induced Toxicity
Problem Substances
:
Oseltamivir (trade name Tamiflu)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The results of this study indicate that working in an occupation with high or medium-high magnetic field exposure may increase the risk of severe cognitive dysfunction.
Apr 16, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Med Med Res. 2014 Apr 16 ;4(8):1641-1662. PMID:
24839595
Article Published Date
: Apr 16, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
Additional Keywords
:
EMF
Anti Therapeutic Actions
:
5G Millimeter Wave Radiation
,
Electromagnetic Fields
,
Electromagnetic Radiation
,
Microwave Radiation
,
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The results suggest that aluminum-induced CRP may in part contribute to a pathophysiological state associated with a chronic systemic inflammation of the human vasculature.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Inorg Biochem. 2015 Aug 1. Epub 2015 Aug 1. PMID:
26265215
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Brain Inflammation
,
C-Reactive Protein
,
Inflammation
Additional Keywords
:
Increased Risk
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Neurotoxic
[+]
There is a high prevlance of gluten sensitivity in Japanese patients with adult-onset cerebellar ataxia.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Intern Med. 2006;45(3):135-40. Epub 2006 Mar 1. PMID:
16508226
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
,
Cerebellar Ataxia
,
Gluten Sensitivity
Problem Substances
:
Gliadin
,
Gluten
,
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
There is a trend toward a higher prevalence of antigliadin antibodies in patients with sporadic ataxia and dominant ataxia.
May 27, 2003
Click here to read the entire abstract
Pubmed Data
: Neurology. 2003 May 27 ;60(10):1674-5. PMID:
12771263
Article Published Date
: May 27, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Ataxia: Dominant
,
Ataxia: Sporadic
Additional Keywords
:
Anti-Gliadin Antibodies
Problem Substances
:
Gliadin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study associates increasing organic mercury exposure from thimerosal-containing hepatitis B vaccines and the subsequent risk of a tic disorder diagnosis.
Jun 01, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Interdiscip Toxicol. 2015 Jun ;8(2):68-76. PMID:
27486363
Article Published Date
: Jun 01, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Tic Disorders
Additional Keywords
:
Vaccine Research
Anti Therapeutic Actions
:
Vaccination: All
,
Vaccination: Hepatitis B
Problem Substances
:
Mercury
,
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study demonstrates that children with autism have higher average levels of several toxic metals, and levels of several toxic metals are strongly associated with variations in the severity of autism.
Feb 01, 2013
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2013 Feb ;151(2):171-80. Epub 2012 Nov 29. PMID:
23192845
Article Published Date
: Feb 01, 2013
Study Type
: Human Study
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
Additional Keywords
:
Heavy Metals and Autism
,
Vaccine Research
Problem Substances
:
Cadmium
,
Lead
,
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study found potential impacts of prenatal BPA exposure on childhood neurodevelopment at 12 and 24 months of age, especially among girls.
Apr 09, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Hyg Environ Health. 2019 Apr 10. Epub 2019 Apr 10. PMID:
30981646
Article Published Date
: Apr 09, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Neurodevelopmental Disorders
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study has empirically demonstrated an association between more widespread exposure to fluoridated water and increased ADHD prevalence in U.S. children and adolescents.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Health. 2015 ;14(1):17. Epub 2015 Feb 27. PMID:
25890329
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Attention Deficit Hyperactivity Disorder
Additional Keywords
:
Toxic Substance Synergy
Problem Substances
:
Lead
,
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study provides new evidence to confirm a significant relationship between exposure to thimerosal and increased diagnosis for delays in development.
Jul 08, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Epidemiol Glob Health. 2015 Jul 9. Epub 2015 Jul 9. PMID:
26166425
Article Published Date
: Jul 08, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Developmental Disorder: Children
Anti Therapeutic Actions
:
Vaccination: Hepatitis B
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study provides the first evidence of associations between antimicrobials and potential adverse birth outcomes in neonates.
Mar 10, 2016
Click here to read the entire abstract
Pubmed Data
: J Hazard Mater. 2016 Mar 11. Epub 2016 Mar 11. PMID:
27156397
Article Published Date
: Mar 10, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Fetal Origin of Adult Disease
Problem Substances
:
Parabens
,
Triclosan
Adverse Pharmacological Actions
:
Anti-Fertility
,
Neurotoxic
[+]
Those with celiac disease may experience neurological damage as a result of the intolerance.
Jul 01, 2007
Click here to read the entire abstract
Pubmed Data
: Gastroenterology. 2007 Jul ;133(1):195-206. Epub 2007 May 3. PMID:
17631142
Article Published Date
: Jul 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Celiac Disease
Pharmacological Actions
:
Apoptotic
Problem Substances
:
Gliadin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Tobacco consumption is associated with increased risk for ALS.
Jan 15, 2000
Click here to read the entire abstract
Pubmed Data
: Am J Epidemiol. 2000 Jan 15;151(2):156-63. PMID:
10645818
Article Published Date
: Jan 15, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Amyotrophic Lateral Sclerosis
,
Nicotine/Tobacco Toxicity
,
Smoking
Problem Substances
:
Nicotine
,
Tobacco
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Users of lipid-lowering drugs are at increased risk of peripheral neuropathy.
Mar 01, 2001
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Pharmacol. 2001 Mar ;56(12):931-3. PMID:
11317483
Article Published Date
: Mar 01, 2001
Study Type
: Human Study
Additional Links
Diseases
:
Neuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Vaccination of any type was associated with an increased risk of CNS ADS onset within the first 30 days after vaccination only in younger (<50 years) individuals (OR, 2.32; 95% CI, 1.18-4.57).
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: JAMA Neurol. 2014 Dec ;71(12):1506-13. PMID:
25329096
Article Published Date
: Nov 30, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Demyelinating Diseases
,
Multiple Sclerosis
,
Vaccine-induced Toxicity
Anti Therapeutic Actions
:
Vaccination: All
Adverse Pharmacological Actions
:
Immunotoxic
,
Neurotoxic
[+]
1800 MHz radiofrequency radiation impairs neurite outgrowth of embryonic neural stem cells which are essential for embryonic brain development.
May 29, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2014 May 29 ;4:5103. Epub 2014 May 29. PMID:
24869783
Article Published Date
: May 29, 2014
Study Type
: Human In Vitro
Additional Links
Additional Keywords
:
Cell Phones
,
electromagnetic fields
,
electromagnetic frequencies
,
electromagnetic radiation
,
EMF
,
Pregnancy
,
Pregnancy And Fetal Growth
,
Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Electromagnetic Radiation: 1.8 GHz
,
Microwave Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Lovastatin exhibits toxicity in human fetal brain cells.
Jan 01, 1995
Click here to read the entire abstract
Pubmed Data
: Neurotoxicol Teratol. 1995 Jan-Feb;17(1):31-9. PMID:
7708017
Article Published Date
: Jan 01, 1995
Study Type
: Human In Vitro
Additional Links
Diseases
:
Abortion: Spontaneous
,
Birth Defects
,
Neurotoxicity
,
Prenatal Chemical Exposures
Pharmacological Actions
:
Antiproliferative
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Neurotoxic
,
Teratogenic
[+]
Mercury is genotoxic to astrocytes even at nanomolar, sub-cytotoxic concentrations.
Mar 01, 2014
Click here to read the entire abstract
Pubmed Data
: Metallomics. 2014 Mar ;6(3):662-71. Epub 2014 Feb 19. PMID:
24549367
Article Published Date
: Mar 01, 2014
Study Type
: Human In Vitro
Additional Links
Diseases
:
DNA damage
Additional Keywords
:
Vaccine Research
Problem Substances
:
Mercury
,
Thimerosal
Adverse Pharmacological Actions
:
Genotoxic
,
Neurotoxic
[+]
Several widely used triazines enhance the production of toxic, aggregation prone Aβ42/Aβ43 amyloids.
Oct 17, 2016
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2016 Oct 18 ;54(4):1593-1605. PMID:
27589520
Article Published Date
: Oct 17, 2016
Study Type
: Human In Vitro
Additional Links
Diseases
:
Alzheimer's Disease
,
Herbicide Toxicity
Additional Keywords
:
Increased Risk
Problem Substances
:
Herbicides
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These results demonstrate a toxic effect of gadolinium-containing MRI contrast agents on mitochondrial respiratory function and cell viability.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Invest Radiol. 2019 Aug ;54(8):453-463. PMID:
31265439
Article Published Date
: Jul 31, 2019
Study Type
: Human In Vitro
Additional Links
Diseases
:
Gadolinium Toxicity
,
Mitochondrial Dysfunction
Problem Substances
:
Gadolinium
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Thimerosal at low nanomolar concentrations was able to induce significant cellular toxicity in human neuron and fetal cells.
May 31, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Environ Chem. 2009 Jun ;91(3-4):735-749. Epub 2009 Jun 11. PMID:
24532866
Article Published Date
: May 31, 2009
Study Type
: Human In Vitro
Additional Links
Problem Substances
:
Aluminum
,
Lead
,
Mercury
,
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Thimerosal impacts nerve growth factor signaling at levels lower than those responsible for cell death.
Jul 01, 2005
Click here to read the entire abstract
Pubmed Data
: Toxicol Sci. 2005 Jul ;86(1):132-40. Epub 2005 Apr 20. PMID:
15843506
Article Published Date
: Jul 01, 2005
Study Type
: Human In Vitro
Additional Links
Diseases
:
DNA damage
Additional Keywords
:
Vaccine Research
Problem Substances
:
Mercury
,
Thimerosal
Adverse Pharmacological Actions
:
Apoptotic
,
Cytotoxic
,
Genotoxic
,
Necrotic
,
Neurotoxic
[+]
Thimerosal stimulates apoptosis in neuroblastoma cells via a neurotoxic mechanism.
Jul 01, 2006
Click here to read the entire abstract
Pubmed Data
: Toxicol Sci. 2006 Jul ;92(1):246-53. Epub 2006 Apr 19. PMID:
16624850
Article Published Date
: Jul 01, 2006
Study Type
: Human In Vitro
Additional Links
Additional Keywords
:
Vaccine Research
Problem Substances
:
Mercury
,
Thimerosal
Adverse Pharmacological Actions
:
Apoptotic
,
Neurotoxic
[+]
This study reveals a similar activity of both ethylmercury and methylmercury. An ethylmercury-glutathione adduct was also identified, suggesting ethylmercury may impair glutathione activity.
Apr 01, 2014
Click here to read the entire abstract
Pubmed Data
: J Trace Elem Med Biol. 2014 Apr ;28(2):125-30. Epub 2014 Feb 9. PMID:
24613139
Article Published Date
: Apr 01, 2014
Study Type
: Human In Vitro
Additional Links
Diseases
:
Oxidative Stress
Additional Keywords
:
Vaccine Research
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Glutathione Down-Regulation
,
Neurotoxic
[+]
A case of multiple sclerosis improvement following removal of heavy metal intoxication has been reported.
Mar 22, 2012
Click here to read the entire abstract
Pubmed Data
: Biometals. 2012 Mar 22. Epub 2012 Mar 22. PMID:
22438029
Article Published Date
: Mar 22, 2012
Study Type
: Human: Case Report
Additional Links
Diseases
:
Multiple Sclerosis
Problem Substances
:
Aluminum
,
Cadmium
,
Lead
,
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
A case report of acute disseminated encephalomyelitis triggered by toxic effect of synthetic cannabinoid black mamba.
Apr 21, 2017
Click here to read the entire abstract
Pubmed Data
: BMJ Case Rep. 2017 Apr 22 ;2017. Epub 2017 Apr 22. PMID:
28433979
Article Published Date
: Apr 21, 2017
Study Type
: Human: Case Report
Additional Links
Diseases
:
Encephalomyelitis
Additional Keywords
:
Encephalomyelitis
,
Synthetic Cannabinoids
Problem Substances
:
Synthetic Cannabinoids
Adverse Pharmacological Actions
:
Neurotoxic
[+]
A series of case studies demonstrate that thimerosal exposure is a major contributing factor to the pathogenesis of autism spectrum disorders.
May 15, 2007
Click here to read the entire abstract
Pubmed Data
: J Toxicol Environ Health A. 2007 May 15;70(10):837-51. PMID:
17454560
Article Published Date
: May 15, 2007
Study Type
: Human: Case Report
Additional Links
Diseases
:
Autism Spectrum Disorders
,
Mercury Poisoning
,
Neurodegenerative Diseases
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
A woman with daily headaches caused by wheat consumption has been reported.
Apr 01, 2005
Click here to read the entire abstract
Pubmed Data
: J Headache Pain. 2005 Apr ;6(2):91-2. Epub 2005 Apr 8. PMID:
16362649
Article Published Date
: Apr 01, 2005
Study Type
: Human: Case Report
Additional Links
Diseases
:
Headache
Problem Substances
:
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Acute glyphosate-surfactant poisoning with neurological sequels and fatal outcome
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Vojnosanit Pregl. 2009 Sep ;66(9):758-62. PMID:
19877558
Article Published Date
: Sep 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Glyphosate Toxicity
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Analysis of a child who developed abnormal neuropsychiatric symptoms after administration of oseltamivir.
Aug 04, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Neurol. 2015 Aug 5 ;15:130. Epub 2015 Aug 5. PMID:
26242979
Article Published Date
: Aug 04, 2015
Study Type
: Human: Case Report
Additional Links
Diseases
:
Psychiatric Disorders
Additional Keywords
:
Gene Expression
,
Oseltamivir (trade name Tamiflu)
,
psychiatric disorders
Problem Substances
:
Oseltamivir (trade name Tamiflu)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Atorvastatin-induced polyneuropathy has been reported.
Nov 04, 2003
Click here to read the entire abstract
Pubmed Data
: Ann Intern Med. 2003 Nov 4 ;139(9):792-3. PMID:
14597471
Article Published Date
: Nov 04, 2003
Study Type
: Human: Case Report
Additional Links
Diseases
:
Neuropathies
,
Polyneuropathies
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Case study: a migraine as initial presentation of celiac disease.
Mar 07, 2012
Click here to read the entire abstract
Pubmed Data
: Rev Neurol (Paris). 2012 Mar 7. Epub 2012 Mar 7. PMID:
22405455
Article Published Date
: Mar 07, 2012
Study Type
: Human: Case Report
Additional Links
Diseases
:
Migraine Disorders
Problem Substances
:
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Fatal exacerbation of peripheral neuropathy during lamivudine therapy has been reported.
Aug 01, 2005
Click here to read the entire abstract
Pubmed Data
: Anaesthesia. 2005 Aug;60(8):806-10. PMID:
16029231
Article Published Date
: Aug 01, 2005
Study Type
: Human: Case Report
Additional Links
Diseases
:
Hepatitis B
,
Mitochondrial Diseases
Additional Keywords
:
Iatrogenic Disease
Problem Substances
:
Lamivudine
Adverse Pharmacological Actions
:
Cardiotoxic
,
Neurotoxic
[+]
Gluten encephalopathy with psychiatric onset has been reported.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Pract Epidemiol Ment Health. 2009;5:16. Epub 2009 Jun 26. PMID:
19558661
Article Published Date
: Jan 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Encephalopathies
,
Gluten Sensitivity
,
Polyneuropathies
Problem Substances
:
Gluten
,
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Glyphosate-induced parkinsonism has been reported.
May 01, 2001
Click here to read the entire abstract
Pubmed Data
: Mov Disord. 2001 May ;16(3):565-8. PMID:
11391760
Article Published Date
: May 01, 2001
Study Type
: Human: Case Report
Additional Links
Diseases
:
Dopamine Levels: Low
,
Glyphosate Toxicity
,
Neurotoxicity
,
Parkinsonian Disorders
,
Substantia Nigra: Damage
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Glyphosphate poisoning resulting in aseptic meningitis has been reported.
Feb 01, 2011
Click here to read the entire abstract
Pubmed Data
: Clin Toxicol (Phila). 2011 Feb;49(2):118-20. PMID:
21370950
Article Published Date
: Feb 01, 2011
Study Type
: Human: Case Report
Additional Links
Diseases
:
Meningitis: Aseptic
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Hearing loss due to aspirin has been reported.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Ther Drug Monit. 2009 Feb;31(1):1-2. PMID:
19155962
Article Published Date
: Feb 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Drug-Induced Toxicity
,
Hearing Loss
Problem Substances
:
Aspirin
,
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Infliximab-induced demyelination may cause visual disturbance mistaken for recurrence of uveitis.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Ocul Immunol Inflamm. 2010 Dec;18(6):482-4. Epub 2010 Aug 25. PMID:
20735341
Article Published Date
: Dec 01, 2010
Study Type
: Human: Case Report
Additional Links
Diseases
:
Demyelinating Diseases
,
Drug-Induced Toxicity
,
Uveitis
Problem Substances
:
Infliximab
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Lead toxicitity may be associated with ALS.
May 01, 1998
Click here to read the entire abstract
Pubmed Data
: Rev Neurol (Paris). 1998 May;154(4):345-7. PMID:
9773065
Article Published Date
: May 01, 1998
Study Type
: Human: Case Report
Additional Links
Diseases
:
Amyotrophic Lateral Sclerosis
,
Bulbar palsy
Problem Substances
:
Lead
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Long-term statin treatment may be associated with chronic peripheral neuropathy.
Jan 01, 1999
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Pharmacol. 1999 Jan ;54(11):835-8. PMID:
10027656
Article Published Date
: Jan 01, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Neuropathies
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Measles vaccine and glyphosate-induced parkinsonism has been reported.
Jun 01, 2003
Click here to read the entire abstract
Pubmed Data
: Arq Neuropsiquiatr. 2003 Jun ;61(2B):381-6. Epub 2003 Jul 28. PMID:
12894271
Article Published Date
: Jun 01, 2003
Study Type
: Human: Case Report
Additional Links
Diseases
:
Glyphosate Toxicity
,
Parkinsonian Disorders
,
Vaccine-induced Toxicity
Anti Therapeutic Actions
:
Vaccination: Measles
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Parkinson's disease due to laboral exposition to paraquat
Oct 31, 2012
Click here to read the entire abstract
Pubmed Data
: Rev Med Inst Mex Seguro Soc. 2012 Nov-Dec;50(6):665-72. PMID:
23331754
Article Published Date
: Oct 31, 2012
Study Type
: Human: Case Report
Additional Links
Diseases
:
Parkinson's Disease
Problem Substances
:
Paraquat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Parkinsonism after chronic occupational exposure to glyphosate has been reported.
Jul 01, 2011
Click here to read the entire abstract
Pubmed Data
: Parkinsonism Relat Disord. 2011 Jul;17(6):486-7. Epub 2011 Mar 2. PMID:
21367645
Article Published Date
: Jul 01, 2011
Study Type
: Human: Case Report
Additional Links
Diseases
:
Parkinsonism
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Peripheral neuropathy associated with simvastatin has been reported.
May 01, 1995
Click here to read the entire abstract
Pubmed Data
: J Neurol Neurosurg Psychiatry. 1995 May ;58(5):625-8. PMID:
7745415
Article Published Date
: May 01, 1995
Study Type
: Human: Case Report
Additional Links
Diseases
:
Peripheral Neuropathies
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
,
Simvastatin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Peripheral neuropathy in two patients with rheumatoid arthritis receiving infliximab treatment has been reported.
Feb 01, 2007
Click here to read the entire abstract
Pubmed Data
: Clin Rheumatol. 2007 Feb;26(2):258-60. Epub 2006 Jul 6. PMID:
16683176
Article Published Date
: Feb 01, 2007
Study Type
: Human: Case Report
Additional Links
Diseases
:
Peripheral Neuropathies
Problem Substances
:
Infliximab
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Peripheral neuropathy induced by lipid-lowering therapy has been reported.
Jul 01, 1998
Click here to read the entire abstract
Pubmed Data
: South Med J. 1998 Jul ;91(7):667-8. PMID:
9671841
Article Published Date
: Jul 01, 1998
Study Type
: Human: Case Report
Additional Links
Diseases
:
Peripheral Neuropathies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
,
Cholesterol Lowering Drugs
,
Lovastatin
,
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Progressive ataxia with palatal tremor due to gluten sensitivity has been reported.
Jan 01, 2012
Click here to read the entire abstract
Pubmed Data
: Mov Disord. 2012 Jan ;27(1):62-3. PMID:
22252893
Article Published Date
: Jan 01, 2012
Study Type
: Human: Case Report
Additional Links
Diseases
:
Ataxia
,
Tremor
Problem Substances
:
Gluten
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Psychiatric disorders with use of simvastatin have been reported.
Jun 26, 1993
Click here to read the entire abstract
Pubmed Data
: Ned Tijdschr Geneeskd. 1993 Jun 26 ;137(26):1312-5. PMID:
8345888
Article Published Date
: Jun 26, 1993
Study Type
: Human: Case Report
Additional Links
Diseases
:
Mood Disorders
,
Psychiatric Disorders
,
Psychological Well-Being
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Reversible encephalopathy and delirium in patients with chronic renal failure who had received ciprofloxacin has been reported.
Apr 01, 2002
Click here to read the entire abstract
Pubmed Data
: Saudi J Kidney Dis Transpl. 2002 Apr-Jun;13(2):163-70. PMID:
17660656
Article Published Date
: Apr 01, 2002
Study Type
: Human: Case Report
Additional Links
Diseases
:
Delirium: Drug-Induced
,
Encephalopathies
Problem Substances
:
Cipro
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Schizophrenic symptoms and SPECT abnormalities in a coeliac patient: regression after a gluten-free diet.
Oct 31, 1997
Click here to read the entire abstract
Pubmed Data
: J Intern Med. 1997 Nov ;242(5):421-3. PMID:
9408073
Article Published Date
: Oct 31, 1997
Study Type
: Human: Case Report
Additional Links
Diseases
:
Celiac Disease
,
Cerebral Hypoperfusion
,
Schizophrenic Disorders
Therapeutic Actions
:
Dietary Modification: Wheat/Gluten Free
Problem Substances
:
Gluten
,
Wheat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Severe statin-induced rhabdomyolysis mimicking Guillain-Barré syndrome in four patients with diabetes mellitus treated with fusidic acid has been reported.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Diabet Med. 2010 Jun ;27(6):696-700. PMID:
20546290
Article Published Date
: Jun 01, 2010
Study Type
: Human: Case Report
Additional Links
Diseases
:
Diabetes Mellitus: Type 2
,
Guillain-Barre Syndrome
,
Rhabdomyolysis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anti-Bacterial Agents
Problem Substances
:
Antibiotics
,
Fusidic acid
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Severe, delayed-onset neuropsychiatric symptoms after administration of high-dose oseltamivir has been reported in a critically ill patient.
Apr 01, 2010
Click here to read the entire abstract
Pubmed Data
: Clin Infect Dis. 2010 Apr 1;50(7):e47-9. PMID:
20192728
Article Published Date
: Apr 01, 2010
Study Type
: Human: Case Report
Additional Links
Diseases
:
Drug-Induced Toxicity
,
Psychiatric Disorders
Problem Substances
:
Oseltamivir (trade name Tamiflu)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Short-term memory loss associated with rosuvastatin has been reported.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2006 Aug ;26(8):1190-2. PMID:
16863497
Article Published Date
: Aug 01, 2006
Study Type
: Human: Case Report
Additional Links
Diseases
:
Memory Disorders
,
Statin-Induced Pathologies
Problem Substances
:
Rosuvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Simvastatin-induced decline in cognition has been reported.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Ann Pharmacother. 2006 Oct ;40(10):1880-3. Epub 2006 Aug 29. PMID:
16940411
Article Published Date
: Oct 01, 2006
Study Type
: Human: Case Report
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Memory Disorders
,
Memory Loss
,
Statin-Induced Pathologies
Problem Substances
:
Simvastatin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Simvastatin-induced mononeuropathy has been reported.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: Arq Neuropsiquiatr. 2004 Jun ;62(2B):540-2. Epub 2004 Jul 20. PMID:
15273860
Article Published Date
: Jun 01, 2004
Study Type
: Human: Case Report
Additional Links
Diseases
:
Neuropathies
,
Statin-Induced Pathologies
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin neuropathy misdiagnosed as diabetic autoimmune polyneuropathy has been reported.
Aug 01, 2005
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Diabetes Care. 2005 Aug ;28(8):2082. PMID:
16043768
Article Published Date
: Aug 01, 2005
Study Type
: Human: Case Report
Additional Links
Diseases
:
Neuropathies
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin therapy has been associated with small fibre neuropathy.
Apr 15, 2003
Click here to read the entire abstract
Pubmed Data
: J Neurol Sci. 2003 Apr 15 ;208(1-2):105-8. PMID:
12639733
Article Published Date
: Apr 15, 2003
Study Type
: Human: Case Report
Additional Links
Diseases
:
Neuropathies
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin-induced memory loss has been reported.
Jun 01, 2001
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2001 Jun ;21(6):767-9. PMID:
11401190
Article Published Date
: Jun 01, 2001
Study Type
: Human: Case Report
Additional Links
Diseases
:
Memory Disorders
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statins-induced MELAS syndrome has been reported.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Eur Neurol. 2007 ;57(4):232-5. Epub 2007 Mar 26. PMID:
17389800
Article Published Date
: Jan 01, 2007
Study Type
: Human: Case Report
Additional Links
Diseases
:
Melas Syndrome
,
Mitochondrial Diseases
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Dopamine, norepinephrine, epinephrine, and serotonin, and their regulating enzymes decreased the in hippocampus of microwave-exposed animals
Sep 01, 2015
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Biophys. 2015 Sep ;73(1):93-100. PMID:
25672490
Article Published Date
: Sep 01, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Learning disorders
,
Memory Disorders
Additional Keywords
:
Brain Function
,
Cognitive Skills
,
Wi-Fi Devices
Anti Therapeutic Actions
:
Microwave Radiation
,
Wi-Fi Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
"Curcumin protects against the oxidative damage induced by the pesticide parathion in the hippocampus of the rat brain."
Feb 02, 2012
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2012 Feb 2. Epub 2012 Feb 2. PMID:
22333997
Article Published Date
: Feb 02, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain Injury: Hippocampal Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Parathion
Adverse Pharmacological Actions
:
Neurotoxic
[+]
"Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy."
Feb 14, 2012
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2012 Feb 14. Epub 2012 Feb 14. PMID:
22338017
Article Published Date
: Feb 14, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Injury: Hippocampal Damage
,
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Doxorubicin
,
Cognitive Decline/Dysfunction
Additional Keywords
:
Drug: Doxorubicin
Anti Therapeutic Actions
:
Chemotherapy
Problem Substances
:
Cyclophosphamide
,
Doxorubicin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
"Neurotoxicity of engineered nanoparticles from metals."
Jan 31, 2012
Click here to read the entire abstract
Pubmed Data
: CNS Neurol Disord Drug Targets. 2012 Feb ;11(1):65-80. PMID:
22229317
Article Published Date
: Jan 31, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Neurotoxicity
Anti Therapeutic Actions
:
Nanotechnology
Problem Substances
:
Nanoparticles
Adverse Pharmacological Actions
:
Neurotoxic
[+]
2.45-GHz microwave radiation impairs hippocampal learning and spatial memory.
Jan 31, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Sci. 2018 Feb 1 ;161(2):349-374. PMID:
29069439
Article Published Date
: Jan 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Memory Disorders
Anti Therapeutic Actions
:
Microwave Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
2.45 GHz microwave radiation impairs learning, memory, and hippocampal synaptic plasticity in the rat.
Oct 20, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Ind Health. 2018 Oct 21:748233718798976. Epub 2018 Oct 21. PMID:
30345889
Article Published Date
: Oct 20, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Learning disorders
Anti Therapeutic Actions
:
Electromagnetic Radiation
,
Microwave Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
A histological study of toxic effects of aluminium sulfate on rat hippocampus.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2015 Feb ;90(2):132-9. Epub 2014 Oct 14. PMID:
25314162
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Neurotoxic
[+]
A white button mushroom extract acted as a potent dietary antioxidant and protects against Al-mediated neurotoxicity, by abrogating neuronal oxidative stress.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Pak J Biol Sci. 2014 Sep ;17(9):1079-82. PMID:
26031030
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
White Button Mushroom
Diseases
:
Aluminum Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Adverse effects of field-realistic doses of glyphosate on honeybee appetitive behavior have been observed.
Jul 24, 2014
Click here to read the entire abstract
Pubmed Data
: J Exp Biol. 2014 Jul 25. Epub 2014 Jul 25. PMID:
25063858
Article Published Date
: Jul 24, 2014
Study Type
: Insect Study
Additional Links
Diseases
:
Bee Colony Collapse
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
After inhalation of particulate matter, heavy metals were absorbed via the bloodstream and selectively accumulated in target organs including blood, brain, liver and lungs in vivo. Aluminum has an affinity for the brain.
Nov 19, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2015 Nov 19 ;5:16936. Epub 2015 Nov 19. PMID:
26582271
Article Published Date
: Nov 19, 2015
Study Type
: Animal Study
Additional Links
Problem Substances
:
Airborne Pollution
,
Heavy Metals
Adverse Pharmacological Actions
:
Hepatotoxic
,
Nephrotoxic
,
Neurotoxic
[+]
Aging can synergistically promote the Atrazine associated dopamine neuron injuries.
Mar 21, 2017
Click here to read the entire abstract
Pubmed Data
: Reprod Toxicol. 2017 Mar 22 ;69:230-241. Epub 2017 Mar 22. PMID:
28341570
Article Published Date
: Mar 21, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Aging
,
Pesticide Toxicity
Problem Substances
:
Herbicides
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Alhydrogel injected at low dose in mouse muscle may selectively induce long-term Al cerebral accumulation and neurotoxic effects.
Nov 27, 2016
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2016 Nov 28. Epub 2016 Nov 28. PMID:
27908630
Article Published Date
: Nov 27, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
Anti Therapeutic Actions
:
Vaccination: All
Problem Substances
:
Aluminum Hydroxide
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aluminium, fluoride and a combination of aluminium-fluoride treatments caused an increase in brain lipid peroxidation products and reactive oxygen species formation.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Pathophysiology. 2015 Mar ;22(1):39-48. Epub 2014 Dec 13. PMID:
25577494
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Brain Inflammation
,
Fluoride Toxicity
,
Neurodegenerative Diseases
,
Oxidative Stress
Additional Keywords
:
Increased Risk
,
Synergistic Toxicity
Problem Substances
:
Aluminum
,
Fluoride
,
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aluminum adjuvants linked to Gulf War illness induces motor neuron death in mice.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Neuromolecular Med. 2007;9(1):83-100. PMID:
17114826
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Diseases
:
Gulf War Syndrome
,
Vaccine-induced Toxicity
Additional Keywords
:
Adjuvant Toxicity
Problem Substances
:
Aluminum Hydroxide
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aluminum appears to enhance the neurotoxic hazards caused by fluoride.
Dec 31, 2008
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2009 ;32(3):215-21. PMID:
19538017
Article Published Date
: Dec 31, 2008
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Lipid Peroxidation
,
Oxidative Stress
Additional Keywords
:
Synergistic Toxicity
Problem Substances
:
Aluminum
,
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aluminum exposure at human dietary levels for 60 days reaches a threshold sufficient to promote memory impairment in rats.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2017 Jan ;31(1):20-30. Epub 2016 Jul 29. PMID:
27473855
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Memory Disorders
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aluminum nanoparticles, which are more neurotoxic than larger aluminum particles, are being investigated for use as vaccine adjuvants.
Jan 10, 2014
Click here to read the entire abstract
Pubmed Data
: J Control Release. 2014 Jan 10 ;173:148-57. Epub 2013 Nov 1. PMID:
24188959
Article Published Date
: Jan 10, 2014
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Vaccine Research
Problem Substances
:
Aluminum
,
Vaccine Adjuvants
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aspartame appears to adversely affect spatial cognition and insulin sensitivity, especially in males.
Jan 01, 2012
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2012 ;7(4):e31570. Epub 2012 Apr 3. PMID:
22509243
Article Published Date
: Jan 01, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Insulin Resistance
Problem Substances
:
Aspartame
Adverse Pharmacological Actions
:
Endocrine Disruptor: Insulin Resistance
,
Neurotoxic
[+]
Aspartame induces brain oxidative stress and vascular congestion in the animal model.
Mar 02, 2012
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2012 Mar 2. Epub 2012 Mar 2. PMID:
22385158
Article Published Date
: Mar 02, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Oxidative Stress
,
Brain: Vascular Congestion
Problem Substances
:
Aspartame
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aspartame ingestion led to alterations in behaviour, cerebral cortical morphology and cerebral oxidative stress markers.
Aug 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Chem Neuroanat. 2016 Aug 24 ;78:42-56. Epub 2016 Aug 24. PMID:
27565676
Article Published Date
: Aug 23, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Oxidative Stress
Problem Substances
:
Aspartame
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Aspirin causes permanent reductions in neural activity in the cochlea and auditory brainstem response.
Jun 14, 2010
Click here to read the entire abstract
Pubmed Data
: Hear Res. 2010 Jun 14;265(1-2):63-9. Epub 2010 Mar 6. PMID:
20214971
Article Published Date
: Jun 14, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Hearing Loss
,
Tinnitus
Problem Substances
:
Aspirin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Astrogliosis and decreased neural viability as consequences of early consumption of aspartame and acesulfame potassium.
Sep 27, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2018 Sep 28. Epub 2018 Sep 28. PMID:
30264280
Article Published Date
: Sep 27, 2018
Study Type
: Animal Study
Additional Links
Problem Substances
:
Acesulfame potassium
,
Aspartame
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Bisphenol A has neurotoxic properties, and may be associated with hyperactivity, in an animal model.
Oct 29, 2011
Click here to read the entire abstract
Pubmed Data
: Toxicol Lett. 2011 Oct 30 ;206(3):300-5. Epub 2011 Aug 22. PMID:
21884766
Article Published Date
: Oct 29, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Attention Deficit Disorder with Hyperactivity
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Bisphenol A impairs the memory function and glutamatergic homeostasis
May 28, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2017 May 29 ;329:75-84. Epub 2017 May 29. PMID:
28572023
Article Published Date
: May 28, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Bisphenol-A could effect spatial memory and synaptic plasticity of the hippocampus in mice.
May 29, 2017
Click here to read the entire abstract
Pubmed Data
: Horm Behav. 2017 May 30. Epub 2017 May 30. PMID:
28576649
Article Published Date
: May 29, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Bisphenol-A had significant inhibitory effects on neural stem cell proliferation and differentiation in rats.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2015 Dec ;52(3):1735-57. Epub 2014 Nov 9. PMID:
25381574
Article Published Date
: Nov 30, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol-A Toxicity
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Brevetoxin exhibits neurotoxic properties.
Dec 01, 2006
Click here to read the entire abstract
Pubmed Data
: Inhal Toxicol. 2006 Dec ;18(14):1109-16. PMID:
17043031
Article Published Date
: Dec 01, 2006
Study Type
: Animal Study
Additional Links
Diseases
:
Red Tide Associated Toxicity
Problem Substances
:
Brevetoxin
,
Red tide
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Brevetoxins from Florida red tide has neuromuscular blocking properties.
Jan 01, 1984
Click here to read the entire abstract
Pubmed Data
: Toxicon. 1984 ;22(1):75-84. PMID:
6539006
Article Published Date
: Jan 01, 1984
Study Type
: Animal Study
Additional Links
Diseases
:
Neuromuscular Diseases
,
Red Tide Associated Toxicity
Problem Substances
:
Brevetoxin
,
Red tide
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Cell phone radiation leads to neuronal loss in 8-week old rats.
Oct 22, 2015
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2015 Oct 22 ;1624:232-238. Epub 2015 Jul 31. PMID:
26239913
Article Published Date
: Oct 22, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Radiation Induced Illness
Additional Keywords
:
Children
,
children's health
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Apoptotic
,
Neurotoxic
[+]
Chlorpyrifos and chlorpyrifos oxon impair the transport of membrane bound organelles in rat cortical axons.
Jun 11, 2017
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2017 Jun 12 ;62:111-123. Epub 2017 Jun 12. PMID:
28600141
Article Published Date
: Jun 11, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Pesticide Toxicity
Problem Substances
:
Chlorpyrifos
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Chlorpyrifos and dichlorvos induced oxidative and neurogenic damage and icreases anxiety-like behaviour in animals.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxics. 2018 Dec 1 ;6(4). Epub 2018 Dec 1. PMID:
30513797
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Anxiety
,
Oxidative Stress
,
Pesticide Toxicity
Problem Substances
:
Chlorpyrifos
,
Dichlorvos
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Chronic exposure to a low level of BPA had adverse effects on brain cells and altered the learning and memory ability of adolescent mice.
May 30, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Pollut. 2017 May 31 ;229:40-48. Epub 2017 May 31. PMID:
28577381
Article Published Date
: May 30, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Chronic exposure to aspartame results in oxidative stress in the brain of albino rats, as well as methanol formation.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Biosci. 2012 Sep ;37(4):679-88. PMID:
22922192
Article Published Date
: Aug 31, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Inflammation
,
Excitotoxicity
,
Lipid Peroxidation
Problem Substances
:
Aspartame
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Chronic exposure to electromagnetic waves results in neuronal degeneration of the auditory system.
Aug 01, 2015
Click here to read the entire abstract
Pubmed Data
: Acta Otolaryngol. 2015 Aug ;135(8):765-70. Epub 2015 Apr 2. PMID:
25836770
Article Published Date
: Aug 01, 2015
Study Type
: Animal Study
Additional Links
Additional Keywords
:
electromagnetic fields
,
electromagnetic radiation
,
EMF
,
Neurodegenerative diseases
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Chronic low-intensity microwave exposure in the frequency range of 900 to 2450 MHz leads to cognitive decline and DNA damage in rats.
May 01, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Toxicol. 2015 May-Jun;34(3):284-90. Epub 2015 Mar 5. PMID:
25749756
Article Published Date
: May 01, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
DNA damage
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Electromagnetic Radiation: 1.8 GHz
,
Electromagnetic Radiation: 2.4 GHz
,
Microwave Radiation
Adverse Pharmacological Actions
:
Genotoxic
,
Neurotoxic
[+]
Chronic microwave exposure could induce cognitive deficit, possibly through alterations in the serotonergic system.
Mar 01, 2015
Click here to read the entire abstract
Pubmed Data
: Physiol Behav. 2015 Mar 1 ;140:236-46. Epub 2014 Dec 24. PMID:
25542888
Article Published Date
: Mar 01, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
Additional Keywords
:
electromagnetic fields
,
electromagnetic frequencies
,
electromagnetic radiation
,
EMF
,
Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Microwave Radiation
,
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Citalopram induced depressive-like behaviour in the offspring of control mothers in this rat study.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Neurosci. 2016 Feb ;43(4):590-600. Epub 2016 Jan 13. PMID:
26669896
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Depression
Additional Keywords
:
Transgenerational Epigenetic Modification
Anti Therapeutic Actions
:
Prenatal Stress
Problem Substances
:
Selective Serotonin Reuptake Inhibitors (SSRIs)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Curcumin provides neuroprotection against BPA-mediated impaired neurogenesis via activation of the Wnt/β-catenin signaling pathway.
May 11, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2015 May 12. Epub 2015 May 12. PMID:
25963729
Article Published Date
: May 11, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Bisphenol-A Toxicity
Pharmacological Actions
:
Neurogenesis
,
Neuroprotective Agents
,
Wnt/β-catenin signaling pathway modulation
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Current findings suggest developmental exposure of rats to BPA may disrupt aspects of spatial navigational learning and memory.
Oct 01, 2015
Click here to read the entire abstract
Pubmed Data
: Horm Behav. 2015 Oct 2. Epub 2015 Oct 2. PMID:
26436835
Article Published Date
: Oct 01, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol-A Toxicity
Problem Substances
:
Bisphenol A
,
Endocrine Disrupting Chemicals (EDCs)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Data demonstrates a negative neurodevelopmental impact of perinatal exposure to thimerosal.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Cerebellum. 2012 Jun ;11(2):575-86. PMID:
22015705
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Learning disorders
,
Neurodevelopmental Disorders
,
Oxidative Stress
Additional Keywords
:
Ethylmercury
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Deltamethrin intranasal administration induces memory, emotional and tyrosine hydroxylase immunoreactivity alterations in rats.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2018 Sep ;142:297-303. Epub 2018 Aug 15. PMID:
30118749
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Parkinsonian Disorders
,
Pesticide Toxicity
Problem Substances
:
Deltamethrin
,
Pesticides
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Differential microRNA expression in the prefrontal cortex of mouse offspring induced by glyphosate exposure during pregnancy and lactation.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Mar ;15(3):2457-2467. Epub 2017 Dec 21. PMID:
29467848
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Glyphosate Toxicity
,
Prenatal Chemical Exposures
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Donepezil markedly potentiates memantine neurotoxicity.
Feb 01, 2008
Click here to read the entire abstract
Pubmed Data
: Neurobiol Aging. 2008 Feb ;29(2):153-67. Epub 2006 Nov 16. PMID:
17112636
Article Published Date
: Feb 01, 2008
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
Pharmacological Actions
:
Apoptotic
Additional Keywords
:
Drug Synergy
Problem Substances
:
Donepezil (trade name Aricept)
,
Memantine
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Early developmental bisphenol-A exposure sex-independently impairs spatial memory.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 ;6:32492. Epub 2016 Aug 31. PMID:
27578147
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Prenatal Chemical Exposures
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Early exposure to a glyphosate-based herbicide affects the central nervous system in rat offspring.
Nov 25, 2015
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2015 Nov 26. Epub 2015 Nov 26. PMID:
26632987
Article Published Date
: Nov 25, 2015
Study Type
: Animal Study
Additional Links
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Embryonic exposure to thimerosal affects early development of serotonergic neurons.
Nov 13, 2011
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2011 Nov 14 ;505(2):61-4. Epub 2011 Jun 6. PMID:
21669256
Article Published Date
: Nov 13, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Prenatal Chemical Exposures
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Excessive fluoride and aluminium intake induces the progression of cell death which inhibit AChE activities and trigger the release of lysosomal and cell cycle proteins.
May 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pathophysiology. 2015 Jun ;22(2):105-15. Epub 2015 Apr 2. PMID:
25863844
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Neurodegenerative Diseases
Additional Keywords
:
Increased Risk
Problem Substances
:
Aluminum
,
Fluoride
,
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Exposure to continuous 900 MHz EMF for 1 h/day during adolescence can disrupt cerebellar morphology and reduce the number of Purkinje cells in rats.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2017 ;92(5):324-330. Epub 2017 May 16. PMID:
28506085
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Anti Therapeutic Actions
:
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Exposure to depleted uranium during gestation and lactation affects brain development in embryos, fetuses and neonates.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2016 Dec ;57:153-162. Epub 2016 Sep 14. PMID:
27639536
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Uranium Poisoning
Problem Substances
:
Uranium: Depleted
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Exposure to GSM 900-MHz mobile radiation impaired inhibitory avoidance memory consolidation in animals.
Jul 17, 2018
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2018 Jul 18. Epub 2018 Jul 18. PMID:
30030983
Article Published Date
: Jul 17, 2018
Study Type
: Animal Study
Additional Links
Anti Therapeutic Actions
:
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
exposure to thimerosal during early postnatal life produces lasting alterations in the densities of brain opioid receptors along with other neuropathological changes, which may disturb brain development.
Oct 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurochem Res. 2010 Nov ;35(11):1840-7. Epub 2010 Aug 28. PMID:
20803069
Article Published Date
: Oct 31, 2010
Study Type
: Animal Study
Additional Links
Anti Therapeutic Actions
:
Vaccination: All
,
Vaccination: Influenza
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Fisetin may slow or prevent neurodegneration and can be utilised as neuroprotective agent against Alzheimer's and Parkinson's disease.
Aug 07, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2015 Aug 8. Epub 2015 Aug 8. PMID:
26411262
Article Published Date
: Aug 07, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
,
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Problem Substances
:
Aluminum Chloride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Fluoride levels in the 100-200 ppm range results in neurotoxicity in rats.
Jul 24, 2010
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2010 Jul 24. Epub 2010 Jul 24. PMID:
20658207
Article Published Date
: Jul 24, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Fluoride Toxicity
Additional Keywords
:
Multi-Generational Effects
Problem Substances
:
Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Fluoxetine appears to prevent recovery of function after dentate gyrus damage.
Sep 01, 2007
Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2007 Sep;18(5-6):521-31. PMID:
17762521
Article Published Date
: Sep 01, 2007
Study Type
: Animal Study
Additional Links
Diseases
:
Memory Disorders
,
Neurodegeneration: Dentate Gyrus
Problem Substances
:
Fluoxetine (trade name Prozac)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Fructose consumption interferes with hippocampus regeneration in the brain.
Feb 25, 2011
Click here to read the entire abstract
Pubmed Data
: Regul Pept. 2011 Feb 25 ;167(1):26-30. Epub 2010 Nov 27. PMID:
21115071
Article Published Date
: Feb 25, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Injury: Hippocampal Damage
,
Fructose-Induced Toxicity
Pharmacological Actions
:
Apoptotic
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Fructose
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Glyphosate and the Roundup formulation is developmentally toxic to the forebrain and midbrain in zebrafish.
Jan 03, 2016
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2016 Jan 4 ;42:45-54. Epub 2016 Jan 4. PMID:
26773362
Article Published Date
: Jan 03, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Glyphosate Toxicity
Additional Keywords
:
Gene Expression
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Glyphosate exposure of the fish (Cnesterodon decemmaculatus) to environmentally relevant concentrations of glyphosate may cause neurotoxicity.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Bull Environ Contam Toxicol. 2012 Jan ;88(1):6-9. PMID:
22002176
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Acetylcholinesterase inhibitor (xenobiotic)
,
Aquacidal
,
Neurotoxic
[+]
Glyphosate pesticides leads to neurodegeneration in Caenorhabditis elegans.
Jun 01, 2011
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2011 Jun ;32(3):331-41. Epub 2011 Mar 3. PMID:
21376751
Article Published Date
: Jun 01, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Neurodegenerative Diseases
,
Neurotoxicity
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
High dose tetrabromobisphenol A impairs hippocampal neurogenesis and memory retention.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2017 Aug ;106(Pt A):223-231. Epub 2017 May 28. PMID:
28564613
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study
Additional Links
Problem Substances
:
Flame Retardants
Adverse Pharmacological Actions
:
Neurotoxic
[+]
High fluoride exposure has multigenerational and cumulative adverse effects on thyroid status, brain health and learning memory in rats.
Jul 14, 2011
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2011 Jul 14. Epub 2011 Jul 14. PMID:
21755305
Article Published Date
: Jul 14, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Fluoride Toxicity
,
Hypothyroidism
,
Prenatal Chemical Exposures
,
Prenatal Nutrition: Learning/Intelligence of Offspring
Problem Substances
:
Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Histological and histomorphometric changes consistent with neuronal damage were seen in the cerebrum, hippocampus and cerebellum.
May 23, 2016
Click here to read the entire abstract
Pubmed Data
: Pathophysiology. 2016 May 24. Epub 2016 May 24. PMID:
27312658
Article Published Date
: May 23, 2016
Study Type
: Animal Study
Additional Links
Problem Substances
:
Monosodium Glutamate (MSG)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease.
Dec 13, 2007
Click here to read the entire abstract
Pubmed Data
: J Biol Chem. 2007 Dec 14 ;282(50):36275-82. Epub 2007 Oct 17. PMID:
17942401
Article Published Date
: Dec 13, 2007
Study Type
: Animal Study
Additional Links
Diseases
:
Amyloidosis
,
Diabetes Mellitus: Type 2
,
Insulin Resistance
Problem Substances
:
Sucrose
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Juvenile exposure to glyphosate through to adulthood led to neurobehavioral changes that stem from the impairment of neuronal developmental processes.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Behav Neurosci. 2017 ;11:146. Epub 2017 Aug 8. PMID:
28848410
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Glyphosate Toxicity
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Learning and memory impairments associated to acetylcholinesterase inhibition and oxidative stress following glyphosate based-herbicide exposure.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2019 Mar 1 ;415:18-25. Epub 2019 Jan 22. PMID:
30682438
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Glyphosate Toxicity
,
Oxidative Stress
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Lipopolysaccharide-induced inflammation in mice increases the penetration of oseltamivir and its active metabolite into the brain.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2009 Oct;61(10):1397-400. PMID:
19814874
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Problem Substances
:
Oseltamivir (trade name Tamiflu)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Liver antioxidant stores protect the brain from oxidative damage as a result of exposure to 900 MHz and 1800 MHz electromagnetic fields.
Dec 01, 2014
Click here to read the entire abstract
Pubmed Data
: J Matern Fetal Neonatal Med. 2014 Dec ;27(18):1915-21. Epub 2014 Apr 9. PMID:
24580725
Article Published Date
: Dec 01, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Glutathione
,
Selenium
,
Vitamin A
,
Vitamin E
Diseases
:
Brain: Oxidative Stress
,
Mobile Phone-Induced Oxidative Stress
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
Additional Keywords
:
electromagnetic fields
,
electromagnetic frequencies
,
Electromagnetic Hypersensitivity
,
electromagnetic radiation
,
EMF
,
Pregnancy And Fetal Growth
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Electromagnetic Radiation: 1.8 GHz
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Neurotoxic
,
Oxidant
[+]
Long term exposure to cell phone frequencies induces apoptosis, mitochondrial oxidative stress and TRPV1 channel activation in the hippocampus.
Jan 12, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2018 Jan 13. Epub 2018 Jan 13. PMID:
29332300
Article Published Date
: Jan 12, 2018
Study Type
: Animal Study
Additional Links
Anti Therapeutic Actions
:
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Long-term 1.8 GHZ RF-EMF induces memory impairments in rats that persist 2 weeks after radiation.
Mar 01, 2013
Click here to read the entire abstract
Pubmed Data
: Electromagn Biol Med. 2013 Mar ;32(1):95-120. Epub 2013 Jan 15. PMID:
23320614
Article Published Date
: Mar 01, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Memory Disorders
Additional Keywords
:
Brain Function
,
Cell Phones
,
electromagnetic fields
,
electromagnetic frequencies
,
electromagnetic radiation
,
EMF
,
Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Electromagnetic Radiation: 1.8 GHz
,
Microwave Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Long-term administration of salicylate (aspirin) may adversely effect presin levels resulting in tinnitus.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Audiol. 2009 Jan;48(1):18-23. PMID:
19173110
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Diseases
:
Hearing Loss
,
Tinnitus
Problem Substances
:
Aspirin
,
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Long-term consumption of artificial sweeteners may have harmful effects on cognition and hippocampal integrity in rats.
Apr 15, 2018
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2018 Apr 16:e22053. Epub 2018 Apr 16. PMID:
29660801
Article Published Date
: Apr 15, 2018
Study Type
: Animal Study
Additional Links
Problem Substances
:
Artificial Sweeteners
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Long-term exposure to cell phone radiation increases apoptosis and oxidative stress while depleting antioxidant activity in the brains of young and adult rats.
Nov 01, 2014
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Biophys. 2014 Nov ;70(2):845-55. PMID:
24801773
Article Published Date
: Nov 01, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Lipid Peroxidation
,
Oxidative Stress
Additional Keywords
:
Cell Phones
,
electromagnetic fields
,
electromagnetic frequencies
,
electromagnetic radiation
,
EMF
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Microwave Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Apoptotic
,
Neurotoxic
,
Oxidant
[+]
Long-term, excessive exposure to mobile phone electromagnetic fields leads to changes in Alzheimer's-related miRNA expression in the brain.
Apr 01, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Radiat Biol. 2015 Apr ;91(4):306-11. Epub 2015 Jan 27. PMID:
25529971
Article Published Date
: Apr 01, 2015
Study Type
: Animal Study
Additional Links
Additional Keywords
:
electromagnetic fields
,
electromagnetic frequencies
,
Electromagnetic Hypersensitivity
,
electromagnetic radiation
,
EMF
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Low cytochrome C oxidase is associated with Alzheimer's disease. This in vivo animal study indicates that certain heavy metals may induce oxidative stress and downregulate cytochrome C oxidase activity.
Mar 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Mol Neurosci. 2011 Mar ;43(3):284-9. Epub 2010 Aug 20. PMID:
20725867
Article Published Date
: Mar 01, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Mitochondrial Dysfunction
Additional Keywords
:
brain health
Problem Substances
:
Aluminum
,
Heavy Metals
Adverse Pharmacological Actions
:
Neurotoxic
,
Oxidant
[+]
Low-dose bisphenol A exposure impairs learning and memory ability with alterations of neuromorphology and neurotransmitters in rats.
Aug 20, 2019
Click here to read the entire abstract
Pubmed Data
: Sci Total Environ. 2019 Aug 21 ;697:134036. Epub 2019 Aug 21. PMID:
31476513
Article Published Date
: Aug 20, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Learning disorders
,
Memory Disorders
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Mechanisms underlying aluminium neurotoxicity related to 14-3-3ζ protein.
Jan 26, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Sci. 2018 Jan 27. Epub 2018 Jan 27. PMID:
29385627
Article Published Date
: Jan 26, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Neurotoxic
[+]
MECHANISMS UNDERLYING THE NEUROTOXICITY INDUCED BY GLYPHOSATE-BASED HERBICIDE IN IMMATURE RAT HIPPOCAMPUS: INVOLVEMENT OF GLUTAMATE EXCITOTOXICITY.
Mar 13, 2014
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2014 Mar 14. Epub 2014 Mar 14. PMID:
24636977
Article Published Date
: Mar 13, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Neurotoxicity
,
Parkinson's Disease
,
Parkinsonism
Problem Substances
:
Glyphosate formulations
,
Roundup (herbicide)
Adverse Pharmacological Actions
:
Excitotoxic
,
Neurotoxic
[+]
Mercury concentration in ambient air may be related to a greater occurrence of autism.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Rev Environ Health. 2011 ;26(2):111-8. PMID:
21905454
Article Published Date
: Jan 01, 2011
Study Type
: Environmental
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
,
Heavy Metal Toxicity
Problem Substances
:
Airborne Pollution
,
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities.
Apr 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Diabetes. 2012 May ;61(5):1234-42. Epub 2012 Mar 16. PMID:
22427376
Article Published Date
: Apr 30, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Diabetes: Cognitive Dysfunction
Pharmacological Actions
:
Antioxidants
Problem Substances
:
Sucrose
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Metal ingestion produced two of the hallmark characteristics of autism: social avoidance and a male-oriented bias in prairie vole.
Nov 12, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Behav Brain Res. 2010 Nov 12 ;213(1):42-9. Epub 2010 Apr 28. PMID:
20433873
Article Published Date
: Nov 12, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
Additional Keywords
:
Heavy Metals and Autism
,
Vaccine Research
Problem Substances
:
Cadmium
,
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Microwave exposure decreases mitochondrial membrane potential, increases DNA fragmentation, and induces apoptosis via a caspase-3-dependent pathway in vitro.
Jan 01, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Med Sci. 2014 ;11(5):426-35. Epub 2014 Mar 9. PMID:
24688304
Article Published Date
: Jan 01, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Mitochondrial Dysfunction
Additional Keywords
:
Brain Function
,
electromagnetic fields
,
electromagnetic frequencies
,
electromagnetic radiation
,
EMF
,
Mitochondria
,
Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Electromagnetic Radiation: 2.4 GHz
,
Microwave Radiation
,
Mobile Phone Radiation
,
Wi-Fi Radiation
Adverse Pharmacological Actions
:
Apoptotic
,
Genotoxic
,
Neurotoxic
[+]
Mobile phone exposure induces oxidative stress in the brain, kidneys, and liver and also increases liver enzyme activity.
Jan 01, 2015
Click here to read the entire abstract
Pubmed Data
: Electromagn Biol Med. 2015 ;34(4):279-84. Epub 2014 Apr 8. PMID:
24712749
Article Published Date
: Jan 01, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Oxidative Stress
,
GGT
,
Lipid Peroxidation
,
Oxidative Stress
Additional Keywords
:
Cell Phones
,
electromagnetic fields
,
electromagnetic frequencies
,
electromagnetic radiation
,
EMF
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Microwave Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Hepatotoxic
,
Malondialdehyde (MDA) Up-Regulation
,
Neurotoxic
,
Oxidant
[+]
Monosodium glutamate is used to induce hypothalamic obesity in a female rat model.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Pediatr Endocrinol Metab. 2011;24(3-4):131-7. PMID:
21648279
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Obesity
,
Obesity: Hypothalamic
Problem Substances
:
Monosodium Glutamate (MSG)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Mutations in neuroligin genes may predispose some populations to hypersensitivity to oxidative stress and mercury compounds, possibly underpinning the link between environmental factors and autism spectrum disorder.
May 01, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Dis Model Mech. 2010 May-Jun;3(5-6):366-76. Epub 2010 Jan 18. PMID:
20083577
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Autism
,
Autism Spectrum Disorders
,
Oxidative Stress
Additional Keywords
:
Heavy Metals and Autism
,
Vaccine Research
Problem Substances
:
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Nano-alumina particles induced Alzheimer disease neuropathology by enhancing the amyloidogenic pathway of amyloid beta production and aggregation.
Sep 20, 2015
Click here to read the entire abstract
Pubmed Data
: Nanoscale. 2015 Sep 21 ;7(37):15225-37. PMID:
26315713
Article Published Date
: Sep 20, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Neurodegenerative Diseases
Additional Keywords
:
Risk Factors
Problem Substances
:
Aluminum oxide
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Nanoalumina stimulates mitochondrial dysfunction, leading to overactive autophagic degradation and results in apoptosis. This was confirmed by upregulation of apoptotic genes in the brains of nanoalumina-treated mice.
Feb 01, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nanomedicine. 2013 Feb ;9(2):212-21. Epub 2012 Jun 9. PMID:
22687898
Article Published Date
: Feb 01, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Mitochondrial Dysfunction
,
Stroke
,
Stroke: Ischemic
Additional Keywords
:
Vaccine Research
Anti Therapeutic Actions
:
Vaccination: All
Problem Substances
:
Aluminum
,
Aluminum oxide
,
Nanoparticles
,
Vaccine Adjuvants
Adverse Pharmacological Actions
:
Apoptotic
,
Blood Brain Barrier Injury
,
Inflammatory
,
Neurotoxic
,
Oxidant
[+]
Neonatal exposure to thimerosal-containing vaccines might induce excitotoxic brain injuries, leading to neurodevelopmental disorders. DHEA may protect against mercury-induced neurotoxicity.
Oct 21, 2011
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2011 Oct 21. Epub 2011 Oct 21. PMID:
22015977
Article Published Date
: Oct 21, 2011
Study Type
: Animal Study
Additional Links
Substances
:
DHEA (Dehydroepiandrosterone)
Diseases
:
Excitotoxicity
,
Mercury Poisoning
,
Vaccine-induced Toxicity
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Mercury
,
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Neonatal HBV vaccination of mice results in neurobehavioral impairments in early adulthood.
Aug 01, 2016
Click here to read the entire abstract
Pubmed Data
: Psychoneuroendocrinology. 2016 Aug 2 ;73:166-176. Epub 2016 Aug 2. PMID:
27501128
Article Published Date
: Aug 01, 2016
Study Type
: Animal Study
Additional Links
Anti Therapeutic Actions
:
Vaccination: Hepatitis B
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Neonicotinoid exposure alters the transcriptome of the developing mammalian brain in a similar way to nicotine exposure.
Oct 03, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2016 Oct 4 ;13(10). Epub 2016 Oct 4. PMID:
27782041
Article Published Date
: Oct 03, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Pesticide Toxicity
Problem Substances
:
Pesticides
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Oral aspartame significantly altered behaviour, anti-oxidant status and morphology of the hippocampus in mice.
Dec 30, 2016
Click here to read the entire abstract
Pubmed Data
: Neurobiol Learn Mem. 2016 Dec 31 ;139:76-88. Epub 2016 Dec 31. PMID:
28049023
Article Published Date
: Dec 30, 2016
Study Type
: Animal Study
Additional Links
Problem Substances
:
Aspartame
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Our findings suggest that BPA inhibits nerve conduction in a manner independent of estrogen receptors.
Jun 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biochem Biophys Rep. 2017 Jul ;10:145-151. Epub 2017 Mar 23. PMID:
28955742
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Paracetamol (acetaminophen) administration during neonatal brain development affects cognitive function and alters its analgesic and anxiolytic response.
Feb 28, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Sci. 2014 Mar ;138(1):139-47. Epub 2013 Dec 21. PMID:
24361869
Article Published Date
: Feb 28, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
Additional Keywords
:
Risk Factors
Problem Substances
:
Acetaminophen
,
Paracetamol
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Paraquat could negatively influence the learning and memory abilities of developing mice.
May 31, 2011
Click here to read the entire abstract
Pubmed Data
: Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011 Jun ;29(6):437-9. PMID:
22096857
Article Published Date
: May 31, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Learning disorders
,
Oxidative Stress
,
Pesticide Toxicity
Additional Keywords
:
Risk Factors
Problem Substances
:
Paraquat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Paraquat induced alteration in the metabolites leads to oxidative stress and neurodegeneration in the exposed organism along with movement disorder.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2016 Jan ;53(1):254-69. Epub 2014 Nov 27. PMID:
25428622
Article Published Date
: Dec 31, 2015
Study Type
: Insect Study
Additional Links
Diseases
:
Oxidative Stress
,
Parkinsonism
Problem Substances
:
Paraquat
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Polysorbate 80 facilitates the transport of superparamagnetic iron oxide nanoparticles through the intact blood brain barrier in rats.
Jan 11, 2016
Click here to read the entire abstract
Pubmed Data
: ACS Appl Mater Interfaces. 2016 05 11 ;8(18):11336-41. Epub 2016 Apr 27. PMID:
27092793
Article Published Date
: Jan 11, 2016
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Vaccine Research
Problem Substances
:
Polysorbate 80
Adverse Pharmacological Actions
:
Neurotoxic
,
Oxidant
[+]
Prenatal and postnatal paracetamol exposure results in modulation of cerebellar neurotransmission with changes concerning mainly 5-HIAA and MHPG levels.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2016 Dec ;68(6):1159-1164. Epub 2016 Sep 7. PMID:
27611980
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Prenatal Chemical Exposures
Additional Keywords
:
acetaminophen
,
Acetaminophen (Tylenol) Toxicity
,
paracetamol
,
Prenatal Chemical Exposures
Problem Substances
:
Acetaminophen
,
Paracetamol
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Prenatal BPA exposure can alter gene expression in the developing brain.
Aug 28, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Endocrinology. 2016 Aug 29:en20161339. Epub 2016 Aug 29. PMID:
27571134
Article Published Date
: Aug 28, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Prenatal Chemical Exposures
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Prenatal stress causes dendritic atrophy in the hippocampus of offspring.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: Dev Neurobiol. 2010 Feb ;70(2):114-25. PMID:
19950194
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Infant Neurological Development
,
Pregnancy: Psychological and Physical Distress.
,
Prenatal Nutrition: Learning/Intelligence of Offspring
Anti Therapeutic Actions
:
Prenatal Stress
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Prenatal stress induces learning deficits and adverse neurological changes in offspring.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Anat Sci Int. 2007 Dec ;82(4):211-7. PMID:
18062150
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Diseases
:
Infant Neurological Development
,
Pregnancy: Psychological and Physical Distress.
,
Prenatal Nutrition: Learning/Intelligence of Offspring
Anti Therapeutic Actions
:
Prenatal Stress
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Prenatally drug treated rat offspring displayed post natal developmental delay till postnatal day 70, and these young adult rats displayed cognitive impairment.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Dev Neurosci. 2015 May ;42:59-67. Epub 2015 Feb 23. PMID:
25720310
Article Published Date
: Apr 30, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Prenatal Chemical Exposures
Additional Keywords
:
Fetal Neurotoxicity
Problem Substances
:
Antipsychotic Drugs
,
Quetiapine
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Prepubescent rats exposed to chronic radiofrequency electromagnetic radiation exhibit learning and memory dysfunction attributed to structural brain changes and decreased viable hippocampal cell count.
Oct 01, 2015
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2015 Oct ;30(5):1193-206. Epub 2015 Jun 3. PMID:
26033310
Article Published Date
: Oct 01, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Learning disorders
,
Memory Disorders
Additional Keywords
:
Brain Function
,
electromagnetic radiation
,
EMF
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Pumpkin fruit peel has a protective effect against carbon tetrachloride induced neurotoxicity.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2014 Nov ;27(6):1967-73. PMID:
25362619
Article Published Date
: Oct 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Pumpkin
Diseases
:
Lipid Peroxidation
,
Neurotoxicity
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
Additional Keywords
:
Dose Response
,
Plant Extracts
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Radiofrequency exposure decreases brain-derived neurotrophic factor and glial-derived neurotrophic factor in the auditory system of rats.
Apr 03, 2014
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2014 Apr 3 ;564:78-82. Epub 2014 Feb 16. PMID:
24548626
Article Published Date
: Apr 03, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Hearing Disorders
Additional Keywords
:
electromagnetic fields
,
electromagnetic frequencies
,
Electromagnetic Hypersensitivity
,
electromagnetic radiation
,
EMF
,
hearing loss
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Rats born to mothers exposed to a 900 MHz electromagnetic field during pregnancy exhibit neuronal loss and pathological effects even after birth.
Jan 01, 2016
Click here to read the entire abstract
Pubmed Data
: J Chem Neuroanat. 2016 09 ;75(Pt B):105-10. Epub 2015 Sep 21. PMID:
26391347
Article Published Date
: Jan 01, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Damage
Additional Keywords
:
Pregnancy
,
Pregnancy And Fetal Growth
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Rats born to mothers exposed to mobile phone radiation exhibit altered electrophysiological properties of CA1 pyramidal neurons, deleteriously impacting cognition.
Jun 01, 2016
Click here to read the entire abstract
Pubmed Data
: Toxicol Ind Health. 2016 Jun ;32(6):968-79. Epub 2014 Mar 6. PMID:
24604340
Article Published Date
: Jun 01, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Birth Defects
,
Cognitive Decline/Dysfunction
,
Learning disorders
Additional Keywords
:
electromagnetic fields
,
electromagnetic frequencies
,
electromagnetic radiation
,
EMF
,
Pregnancy
,
Pregnancy And Fetal Growth
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Microwave Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Rats exposed to low iodine and high fluoride exhibit changes in brain proteins that may be associated with neurotoxicity.
Apr 03, 2010
Click here to read the entire abstract
Pubmed Data
: Arch Toxicol. 2010 Apr 3. Epub 2010 Apr 3. PMID:
20364248
Article Published Date
: Apr 03, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Prenatal Nutrition: Learning/Intelligence of Offspring
Problem Substances
:
Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Rats exposed to mobile phone radiation present with higher oxidative stress, reduced antioxidant activity, and extensive neurodegeneration in the brain.
Dec 01, 2014
Click here to read the entire abstract
Pubmed Data
: Neurol Res. 2014 Dec ;36(12):1072-9. Epub 2014 May 26. PMID:
24861496
Article Published Date
: Dec 01, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Anxiety Disorders
,
Brain: Oxidative Stress
,
Cognitive Decline/Dysfunction
,
Lipid Peroxidation
,
Neurodegenerative Diseases
,
Oxidative Stress
Additional Keywords
:
Cell Phones
,
electromagnetic fields
,
electromagnetic frequencies
,
Electromagnetic Hypersensitivity
,
electromagnetic radiation
,
EMF
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Microwave Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Neurotoxic
,
Oxidant
[+]
Repeated exposure with mercury accelerates progression of multiple sclerosis through mitochondrial damage.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Pharm Res. 2016 ;15(4):834-841. PMID:
28243280
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Mercury Poisoning
,
Multiple Sclerosis
Problem Substances
:
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Repetitive administration of aluminium to neonatal mice in amounts comparable to those to children receive via routine vaccinations result in neurodisruptive effects.
Oct 31, 2013
Click here to read the entire abstract
Pubmed Data
: J Inorg Biochem. 2013 Nov ;128:237-44. Epub 2013 Jul 19. PMID:
23932735
Article Published Date
: Oct 31, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Autism Spectrum Disorders
Anti Therapeutic Actions
:
Vaccination: All
Problem Substances
:
Aluminum
,
Vaccine Adjuvants
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Report of final results regarding brain and heart tumors in Sprague-Dawley rats exposed from prenatal life until natural death to mobile phone radiofrequency fields.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Res. 2018 Aug ;165:496-503. Epub 2018 Mar 7. PMID:
29530389
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Cancer
Anti Therapeutic Actions
:
Electromagnetic Radiation: 1.8 GHz
,
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Carcinogenic
,
Cardiotoxic
,
Neurotoxic
[+]
Roundup causes oxidative stress in liver and inhibits acetylcholinesterase in muscle and brain of a neotropical fish.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Chemosphere. 2010 Jan;78(3):294-9. Epub 2009 Nov 11. PMID:
19910015
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Environmental Pollutant
Problem Substances
:
Glyphosate
,
Roundup (herbicide)
Adverse Pharmacological Actions
:
Aquacidal
,
Hepatotoxic
,
Neurotoxic
,
Oxidant
[+]
Simvastatin delays nerve regeneration.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Folia Neuropathol. 2010;48(1):49-56. PMID:
20383811
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Neuropathies
Problem Substances
:
Simvastatin
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Simvastatin exhibits neurotoxicity in the animal model.
Jan 15, 2007
Click here to read the entire abstract
Pubmed Data
: Glia. 2007 Jan 15 ;55(2):130-43. PMID:
17078030
Article Published Date
: Jan 15, 2007
Study Type
: Animal Study
Additional Links
Diseases
:
Multiple Sclerosis
,
Statin-Induced Pathologies
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Sodium fluoride affects zebrafish behaviour and alters mRNA expressions of biomarker genes in the brain.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2015 Sep ;40(2):352-9. Epub 2015 Jul 14. PMID:
26245810
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study
Additional Links
Problem Substances
:
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Some statin drugs are may cause neurological problems due to their ability to cross the blood-brain barrier.
Feb 01, 1994
Click here to read the entire abstract
Pubmed Data
: Pharm Res. 1994 Feb ;11(2):305-11. PMID:
8165193
Article Published Date
: Feb 01, 1994
Study Type
: Animal Study
Additional Links
Diseases
:
Blood-Brain-Barrier Disorders
,
Statin-Induced Pathologies
Problem Substances
:
Lovastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin drugs adversely effect memory likely through depletion of coenzyme q10 and interference with mitochondrial function in the brain.
Jul 08, 2011
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2011 Jul 8. Epub 2011 Jul 8. PMID:
21763754
Article Published Date
: Jul 08, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Drug-Induced Nutrient Depletion: Statin Drugs
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin drugs exhibit myotoxic, neurotoxic, hepatotoxic and testicule damaging properties in the anima model.
Jul 01, 1996
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Pathol. 1996 Jul-Aug;24(4):468-76. PMID:
8864188
Article Published Date
: Jul 01, 1996
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Damage
,
Liver Damage: Drug-Induced
,
Statin-Induced Pathologies
,
Testicular Diseases
Pharmacological Actions
:
Anticholesteremic Agents
,
Enzyme Inhibitors
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
,
Myotoxicity
,
Neurotoxic
[+]
Statin drugs exhibit neurotoxicity in an animal neuronal cell line.
Sep 01, 2011
Click here to read the entire abstract
Pubmed Data
: Eur Rev Med Pharmacol Sci. 2011 Sep ;15(9):985-91. PMID:
22013720
Article Published Date
: Sep 01, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Brain Damage
,
Neurodegenerative Diseases
,
Statin-Induced Pathologies
Pharmacological Actions
:
Antiproliferative
Problem Substances
:
Atorvastatin
,
Lovastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin drugs inhibit central nervous system remyelination.
Apr 06, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Pathol. 2009 Apr 6. PMID:
19349355
Article Published Date
: Apr 06, 2009
Study Type
: Animal Study
Additional Links
Diseases
:
Demyelinating Diseases
,
Statin-Induced Pathologies
Additional Keywords
:
Multiple Sclerosis Contraindications
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Statin drugs interfere with neurological healing by inhibiting myelin formation.
Dec 10, 2008
Click here to read the entire abstract
Pubmed Data
: J Neurosci. 2008 Dec 10 ;28(50):13609-14. PMID:
19074034
Article Published Date
: Dec 10, 2008
Study Type
: Animal Study
Additional Links
Diseases
:
Demyelinating Diseases
,
Drug-Induced Nutrient Depletion: Statin Drugs
,
Multiple Sclerosis
Additional Keywords
:
Remyelination
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Subchronic intake of aspartame and soft drink significantly disrupted the brain energy production.
Jun 27, 2017
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2017 Jun 28. Epub 2017 Jun 28. PMID:
28660358
Article Published Date
: Jun 27, 2017
Study Type
: Animal Study
Additional Links
Problem Substances
:
Aspartame
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Sucralose induces biochemical responses, including neurotoxicity, in Daphnia magna.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2014 ;9(4):e92771. Epub 2014 Apr 3. PMID:
24699280
Article Published Date
: Dec 31, 2013
Study Type
: Insect Study
Additional Links
Diseases
:
Lipid Peroxidation
Additional Keywords
:
Lipid Peroxidation
,
Splenda
,
Sucralose
Problem Substances
:
Sucralose (aka Splenda)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Sucralose inhibits thyroid function and metabolism in doses within the range of the human acceptable daily intake.
Dec 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Nutr. 2016 Dec 31. Epub 2016 Dec 31. PMID:
28040879
Article Published Date
: Dec 30, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
HPA Axis Dysregulation
,
Hypothyroidism
,
Overweight
Additional Keywords
:
HPA Axis Dysregulation
,
hypothyroidism
,
overweight
,
Splenda
,
Sucralose
Problem Substances
:
Sucralose (aka Splenda)
Adverse Pharmacological Actions
:
Endocrine Disruptor: Thyroid
,
Neurotoxic
[+]
Synergistic oxidative impact of aluminum chloride and sodium fluoride exposure during early stages of brain development.
Feb 19, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2019 Feb 20. Epub 2019 Feb 20. PMID:
30788699
Article Published Date
: Feb 19, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
,
Brain: Oxidative Stress
,
Fluoride Toxicity
Additional Keywords
:
Synergistic Toxicity
Problem Substances
:
Aluminum Chloride
,
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Taurine protected against sodium fluoride induced neurotoxicity.
Nov 10, 2016
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2016 Nov 11 ;261:1-10. Epub 2016 Nov 11. PMID:
27840156
Article Published Date
: Nov 10, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Taurine
Diseases
:
Fluoride Toxicity
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Sodium Fluoride
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The administration of vitamin B complex (in combination with a steroid) early before clinical signs of organophosphates exposure are manifest is effective in alleviating neuropathy.
Aug 31, 2004
Click here to read the entire abstract
Pubmed Data
: J Occup Health. 2004 Sep ;46(5):359-64. PMID:
15492452
Article Published Date
: Aug 31, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Riboflavin (Vitamin B-2)
,
Thiamine (B-1)
,
Vitamin B-12
,
Vitamin B-6
Diseases
:
Aerotoxic Syndrome
,
Neurodegenerative Diseases
,
Neuropathies
Pharmacological Actions
:
Neuroprotective Agents
Anti Therapeutic Actions
:
Air Travel
Problem Substances
:
Organophosphates
,
Tricresyl phosphates (TCPs)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The brain barrier systems does not limit the access of the lipophilic BPA to the brain.
May 31, 2004
Click here to read the entire abstract
Pubmed Data
: Toxicol Ind Health. 2004 Jun ;20(1-5):41-50. PMID:
15807407
Article Published Date
: May 31, 2004
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol-A Toxicity
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The cognitive deficits observed in postmenopausal women treated with aromatase inhibitors may be due to their adverse effect on hippocampal function.
Mar 01, 2010
Click here to read the entire abstract
Pubmed Data
: Endocrinology. 2010 Mar;151(3):1153-60. Epub 2010 Jan 22. PMID:
20097718
Article Published Date
: Mar 01, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Breast Cancer
,
Breast Cancer: Prevention
,
Drug-Induced Toxicity
Problem Substances
:
Aromatase Inhibitor Drugs
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The current study revealed that maternal exposure to WiFi radiofrequencies led to various adverse neurological effects in the offspring of animals.
May 31, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2017 Jun ;52:239-247. Epub 2017 Apr 22. PMID:
28458069
Article Published Date
: May 31, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Oxidative Stress
,
Neurodevelopmental Disorders
Additional Keywords
:
Risk Factors
Anti Therapeutic Actions
:
Mobile Phone Radiation
,
Wi-Fi Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The long term exposure to 900-1800 MHz frequency radiations emitted from 2G mobile phone could cause significantly reduced neuron density.
Jul 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Diagn Res. 2016 Aug ;10(8):AF01-6. Epub 2016 Aug 1. PMID:
27656427
Article Published Date
: Jul 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Electromagnetic Radiation
Anti Therapeutic Actions
:
Electromagnetic Radiation
,
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Neurotoxic
[+]
The presence of nanoplastics can increase BPA bioavailability and cause neurotoxicity in adult zebrafish.
Aug 04, 2017
Click here to read the entire abstract
Pubmed Data
: Sci Total Environ. 2017 Aug 5 ;609:1312-1321. Epub 2017 Aug 5. PMID:
28793400
Article Published Date
: Aug 04, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
Additional Keywords
:
Bisphenol A
,
Bisphenol Toxicity
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
There are lasting neuropathological changes in rat brain after intermittent neonatal administration of thimerosal.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Folia Neuropathol. 2010 ;48(4):258-69. PMID:
21225508
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Infant Chemical Exposures
,
Neurodegenerative Diseases
,
Vaccine-induced Toxicity
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
There is evidence that aspirin causing tinnitus in the rat model.
Feb 17, 2010
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2010 Feb 17;165(4):1323-32. Epub 2009 Dec 1. PMID:
19958810
Article Published Date
: Feb 17, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Hearing Loss
,
Tinnitus
Problem Substances
:
Aspirin
,
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These data reveal an anxiogenic effect of bisphenol S.
Jul 09, 2019
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2019 Jul 10 ;132:110670. Epub 2019 Jul 10. PMID:
31301325
Article Published Date
: Jul 09, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Anxiety
,
Bisphenol Toxicity
Problem Substances
:
Bisphenol S
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These findings demonstrate that aspartame metabolites could be a contributing factor for the development of oxidative stress in the brain.
Mar 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Food Drug Anal. 2018 Apr ;26(2):903-916. Epub 2017 Dec 6. PMID:
29567262
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Oxidative Stress
Problem Substances
:
Aspartame
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These findings implicate a genetic influence in autistic disorders and provides a model for investigating thimerosal related neurotoxicity.
Aug 31, 2004
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Psychiatry. 2004 Sep ;9(9):833-45. PMID:
15184908
Article Published Date
: Aug 31, 2004
Study Type
: Animal Study
Additional Links
Diseases
:
Autism Spectrum Disorders
,
Autoimmune Diseases
,
Neurodevelopmental Disorders
Additional Keywords
:
Genomic Variation
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These results indicate that chronic paternal nicotine exposure can impact the behavior of offspring.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Neurotoxicol Teratol. 2019 Jul - Aug;74:106808. Epub 2019 May 16. PMID:
31103693
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Nicotine/Tobacco Toxicity
,
Prenatal Chemical Exposures
Problem Substances
:
Nicotine
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These results indicate that embryonic exposure to thimerosal produces lasting impairment of brain monoaminergic system.
Feb 28, 2013
Click here to read the entire abstract
Pubmed Data
: Brain Dev. 2013 Mar ;35(3):261-4. Epub 2012 Jun 1. PMID:
22658806
Article Published Date
: Feb 28, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Prenatal Chemical Exposures
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These results reinforce the likelihood that flame retardants act as developmental neurotoxicants.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicology. 2017 09 1 ;390:32-42. Epub 2017 Aug 26. PMID:
28851516
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Neurodegenerative Diseases
Problem Substances
:
Flame Retardants
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These results show that BPA-free products are not necessarily safer and support the removal of all bisphenols from consumer merchandise.
Feb 02, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Proc Natl Acad Sci U S A. 2015 Feb 3 ;112(5):1475-80. Epub 2015 Jan 12. PMID:
25583509
Article Published Date
: Feb 02, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Neurodevelopmental Disorders
Problem Substances
:
Bisphenol A
,
Bisphenol S
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These results showed that circRNAs are aberrantly expressed in the hippocampus of mice with perinatal glyphosate exposure.
Apr 25, 2018
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2018 Apr 26. Epub 2018 Apr 26. PMID:
29705695
Article Published Date
: Apr 25, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Glyphosate Toxicity
,
Prenatal Chemical Exposures
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
These results support that long-term exposure to a GSM-like 2100MHz electromagnetic fields causes an increase in neuronal degeneration and apoptosis in the auditory system.
Dec 01, 2017
Click here to read the entire abstract
Pubmed Data
: Braz J Otorhinolaryngol. 2017 Nov - Dec;83(6):691-696. Epub 2016 Nov 5. PMID:
27865708
Article Published Date
: Dec 01, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Auditory Diseases
Additional Keywords
:
EMF
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Electromagnetic Radiation: 1.8 GHz
,
Electromagnetic Radiation: 2.4 GHz
,
Microwave Radiation
,
Mobile Phone Radiation
Adverse Pharmacological Actions
:
Apoptotic
,
Neurotoxic
[+]
Thimerosal exerts sex-dependent effects and may induce local brain hypothyroidism.
Jun 01, 2012
Click here to read the entire abstract
Pubmed Data
: J Physiol Pharmacol. 2012 Jun ;63(3):277-83. PMID:
22791642
Article Published Date
: Jun 01, 2012
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Vaccine Research
Problem Substances
:
Mercury
,
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This animal study demonstrates that prenatal mobile phone electromagnetic field exposure alters electrophysiological properties of neurons in rats.
Oct 10, 2013
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2013 Oct 10 ;250:588-98. Epub 2013 Jul 29. PMID:
23906636
Article Published Date
: Oct 10, 2013
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Pregnancy
,
Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This animal study suggests RF-EMF radiation stresses the brain.
Mar 01, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2017 Mar ;21(2):179-188. Epub 2017 Feb 21. PMID:
28280411
Article Published Date
: Mar 01, 2017
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Brain Function
,
Cell Phones
,
electromagnetic fields
,
electromagnetic radiation
,
EMF
Anti Therapeutic Actions
:
Electromagnetic Fields
,
Electromagnetic Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Apoptotic
,
Neurotoxic
[+]
This data contributes to the knowledge of the neurotoxic effects of glyphosate-based herbicides.
Jun 10, 2018
Click here to read the entire abstract
Pubmed Data
: Chemosphere. 2018 Jun 11 ;209:353-362. Epub 2018 Jun 11. PMID:
29935464
Article Published Date
: Jun 10, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Glyphosate Toxicity
Problem Substances
:
Glyphosate
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This demonstrates the beneficial effects of resistance exercise against the prejudice of motor condition and impairment of memory induced by MSG.
Apr 22, 2017
Click here to read the entire abstract
Pubmed Data
: Exp Physiol. 2017 Apr 23. Epub 2017 Apr 23. PMID:
28436061
Article Published Date
: Apr 22, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
MSG Toxicity
Therapeutic Actions
:
Exercise: Resistance Training
Problem Substances
:
Monosodium Glutamate (MSG)
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This report systematically explains pathways possibly involved in thimerosal-induced autistic-like behaviour.
May 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Sci. 2014 Jun ;139(2):452-65. Epub 2014 Mar 27. PMID:
24675092
Article Published Date
: May 31, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Autism
,
Neurodegenerative Diseases
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study demonstrates that there are sex-and structure-specific changes to thioredoxin system antioxidant systems responses in methylmercury neurotoxicity.
Jan 01, 2016
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2016 09 ;56:118-126. Epub 2016 Jul 22. PMID:
27456245
Article Published Date
: Jan 01, 2016
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Vaccine Research
Problem Substances
:
Mercury
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study proposes that BPA affects DNA methylation of Sc1a1 during neural development.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2011 ;6(9):e25448. Epub 2011 Sep 28. PMID:
21980460
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
Fetal Origin of Adult Disease
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study provides further evidence that polysorbate 80 carries compounds over the blood brain barrier.
Feb 01, 2008
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Pubmed Data
: Bull Exp Biol Med. 2008 Feb ;145(2):259-62. PMID:
19023984
Article Published Date
: Feb 01, 2008
Study Type
: Animal Study
Additional Links
Additional Keywords
:
Vaccine Research
Problem Substances
:
Polysorbate 80
Adverse Pharmacological Actions
:
Blood Brain Barrier Injury
,
Neurotoxic
[+]
This study raised serious concerns about adverse neurodevelopmental disorders such as autism in humans after thimerosal containing vaccines.
Oct 31, 2013
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Pubmed Data
: World J Pediatr. 2013 Nov ;9(4):356-60. Epub 2013 Nov 14. PMID:
24235069
Article Published Date
: Oct 31, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Autism
,
Neurodevelopmental Disorders
Problem Substances
:
Thimerosal
Adverse Pharmacological Actions
:
Neurotoxic
[+]
This study supports previous findings that indicate aluminum is a persistent bioaccumulator in vivo via aluminum adjuvant intramuscular injection.
Nov 01, 2015
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Pubmed Data
: J Inorg Biochem. 2015 Nov ;152:199-205. Epub 2015 Jul 22. PMID:
26384437
Article Published Date
: Nov 01, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Aluminum Toxicity
Additional Keywords
:
Vaccine Research
Anti Therapeutic Actions
:
Vaccination: All
Problem Substances
:
Aluminum
,
Vaccine Adjuvants
Adverse Pharmacological Actions
:
Bioaccumulator
,
Neurotoxic
[+]
Treatment with quercetin may represent a therapeutic strategy to attenuate the neuronal death against aluminum-induced neurodegeneration.
Mar 01, 2016
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Pubmed Data
: Neuroscience. 2016 Mar 2. Epub 2016 Mar 2. PMID:
26944603
Article Published Date
: Mar 01, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Aluminum Toxicity
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Triclosan can induce neurodegenerative effects in developing rat brains.
Dec 31, 2015
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Article Publish Status
: This is a free article.