Bisphenol Toxicity

Name	AC	CK
Melatonin	14	22
Citrus naringin	7	13
Curcumin	6	13
Ginseng (Korean)	3	13
Folate	2	12
Quercetin	8	11
Selenium	6	10
Lycopene	5	9
Resveratrol	5	8
NAC (N-acetyl-L-cysteine)	4	7
Vitamin E	4	7
EGCG (Epigallocatechin gallate)	4	6
Vitamin C	3	5
Alpha-Lipoic Acid	2	4
Arugula	2	4
Coenzyme Q10	2	4
Crocin	2	4
Folic Acid	2	4
Grape Seed Extract	2	4
Hydroxytyrosol	2	4
Luteolin	2	4
Oleuropein	2	4
Probiotics	2	4
Taurine	2	4
Thymoquinone	1	4
Tualang Honey	2	4
Gallic Acid	2	3
Genistein	2	3
Ginger	2	3
Aloe Vera	1	2
Ashwagandha	1	2
Asparagus	1	2
Astaxanthin	1	2
Astragaloside	1	2
Astragalus	1	2
Bifidobacterium	1	2
Bifidobacterium Breve	1	2
Boron	1	2
Cordyceps Militaris	1	2
Curry Tree	1	2
Fenugreek	1	2
Folate: Dietary	1	2
Frankincense	1	2
Ginkgo biloba	1	2
Ginseng	1	2
Indole-3-Carbinol	1	2
Kefir	1	2
Lactobacillus casei	1	2
Linoleic acid	1	2
Nigella sativa (aka Black Seed)	1	2
Oak	1	2
Olive leaf extract	1	2
Omega-3 Fatty Acids	1	2
Pumpkin Seed Oil/Meal	1	2
Sesame Seeds	1	2
Silymarin	1	2
Soy	1	2
Vitamin D	1	2
Bacillus pumilus	1	1
Black Tea	1	1
Fermented Foods and Beverages	1	1
Green Tea	1	1
Kaempferol	1	1
Kimchi	1	1
Lactobacillus plantarum	1	1
Progesterone	1	1
Royal Jelly	1	1
Rutin	1	1
Silibinin	1	1
Turmeric	1	1
Yoghurt	1	1

Name	AC	CK
Bisphenol A	781	2686
Bisphenol S	157	495
Bisphenol F	63	208
Phthalates	36	161
Parabens	8	36
Endocrine Disrupting Chemicals (EDCs)	7	31
Triclosan	6	30
Bisphenol AP	4	14
Benzophenones	3	12
Disinfection by-products: In Drinking Water	2	11
Organophosphates	2	11
Perfluorinated compounds	1	10
Bisphenols	2	5
BisGMA-based dental products	4	4
Cadmium	3	4
8-tetrachlorodibenzo-p-dioxin (TCDD)	2	3
Bisphenol P	2	3
Endocrine Disruptors	2	3
Pesticides	2	3
17beta-estradiol	2	2
Arsenic	1	2
Nonylphenol	1	2
Polychlorinated biphenyls (PCBs)	2	2
Sugar Sweetened Beverages	1	2
Titanium Dioxide	1	2
Aluminium Cans	1	1
Benzo(a)pyrene	1	1
Bisphenol M	1	1
Chlorinated Water	1	1
Dental Amalgams	1	1
Energy Drinks	1	1
Octylphenol	1	1
Perfluorooctanoic acid (PFOA)	1	1
Polybrominated diphenylethers (PBDEs)	1	1
Tamoxifen	1	1

Name	AC	CK	Focus
Sweating	1	10

Name	AC	CK	Focus
Dental Sealant Use	1	1

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BPA might be involved in the insulin-resistance and hyperandrogenism of polycystic ovary syndrome.Nov 29, 2017

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Pubmed Data : Gynecol Endocrinol. 2017 Nov 30:1-8. Epub 2017 Nov 30. PMID: 29191127

Article Published Date : Nov 29, 2017

Study Type : Meta Analysis, Review

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Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome

Problem Substances : Bisphenol A

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Pubmed Data : J Pharm Biomed Anal. 2017 Jun 5 ;140:105-112. Epub 2017 Mar 10. PMID: 28346880

Article Published Date : Jun 04, 2017

Study Type : Human In Vitro, Human Study

Additional Links

Diseases : Bisphenol Toxicity, Chemically-Induced Liver Damage

Additional Keywords : Bisphenol A, Bisphenol Toxicity, Chemically-Induced Liver Damage

Problem Substances : Bisphenol A

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Bisphenol A was found to influence serum C-reactive protein levels in this study. Jul 11, 2016

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Pubmed Data : Glob J Health Sci. 2016 Jul 12 ;9(3):59895. Epub 2016 Aug 12. PMID: 27806497

Article Published Date : Jul 11, 2016

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, C-Reactive Protein, Inflammation

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

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Bisphenol A, S, and F exposure, ESR1/2, CAT, and eNOS genetic polymorphisms, and the risk of hypertension.Aug 22, 2021

Bisphenols accumulation in the white matter-enriched brain tissue could signify that they are able to cross the blood-brain barrier.May 28, 2018

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Pubmed Data : Environ Res. 2016 Sep 15 ;151:689-697. Epub 2016 Sep 15. PMID: 27640068

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Pubmed Data : Environ Sci Pollut Res Int. 2019 Jul 27. Epub 2019 Jul 27. PMID: 31352597

Article Published Date : Jul 26, 2019

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A

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Canned vegetable and fruit, canned pasta, and canned soup were associated with higher levels of urinary BPA concentrations.Jun 26, 2016

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Pubmed Data : Environ Res. 2016 Jun 27 ;150:375-382. Epub 2016 Jun 27. PMID: 27362993

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Pubmed Data : Environ Res. 2017 Jul 14 ;158:566-575. Epub 2017 Jul 14. PMID: 28715785

Article Published Date : Jul 13, 2017

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures

Problem Substances : Bisphenol A , Phthalates

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Pubmed Data : Epidemiology. 2017 Oct ;28 Suppl 1:S3-S9. PMID: 29028670

Article Published Date : Sep 30, 2017

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Female Reproductive Development Abnormalities

Problem Substances : Bisphenol A

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Fetal exposure to bisphenols and phthalates and childhood bone mass.Jun 30, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Res. 2020 Jul ;186:109602. Epub 2020 May 1. PMID: 32668547

Article Published Date : Jun 30, 2020

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Bone Diseases, Fetal Origin of Adult Disease, Phthalate Toxicity

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A , Phthalates

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Higher dermal exposure of cashiers to BPA and its association with DNA oxidative damage.Dec 31, 2016

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Pubmed Data : Environ Int. 2017 Jan ;98:69-74. Epub 2016 Oct 8. PMID: 27729163

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, DNA damage

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

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Higher exposure to BPA was associated with abnormal sperm tail morphology.Aug 20, 2019

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Pubmed Data : Reprod Toxicol. 2019 Aug 21. Epub 2019 Aug 21. PMID: 31445078

Article Published Date : Aug 20, 2019

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Infertility: Male

Problem Substances : Bisphenol A

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Pharmacological Actions : Chemopreventive, Malondialdehyde Down-regulation

Additional Keywords : Detoxification, Plant Extracts

Problem Substances : Bisphenol A

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Maternal exposure to high level of BPA during pregnancy might increase the detrimental effects of abnormal conducts in their preschool children.Feb 09, 2018

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Pubmed Data : Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Feb 10 ;39(2):188-193. PMID: 29495203

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Pubmed Data : Environ Health Perspect. 2019 Nov ;127(11):117004. Epub 2019 Nov 27. PMID: 31774309

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Parabens-Associated Toxicity

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A , Parabens

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Occupational exposure of cashiers to bisphenol S via thermal paper.May 21, 2018

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Pubmed Data : Toxicol Lett. 2018 May 22. Epub 2018 May 22. PMID: 29800715

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Prenatal maternal exposure to BPA may lead to alterations in white matter microstructure in preschool aged children.Oct 14, 2019

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Pubmed Data : Environ Health. 2019 Oct 15 ;18(1):85. Epub 2019 Oct 15. PMID: 31615514

Article Published Date : Oct 14, 2019

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Neurotoxic

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Prenatal urinary BPA concentration was associated with some aspects of child behavior in this cohort.Jun 15, 2017

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Pubmed Data : Environ Health Perspect. 2017 Jun 16 ;125(6):067008. Epub 2017 Jun 16. PMID: 28657891

Pubmed Data : Ecotoxicol Environ Saf. 2020 Feb 10 ;192:110300. Epub 2020 Feb 10. PMID: 32058166

Article Published Date : Feb 09, 2020

Study Type : Human Study

Additional Links

Diseases : Angina Pectoris, Bisphenol Toxicity, Cardiovascular Diseases, Heart Failure, Myocardial Infarction

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Cardiotoxic

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Pubmed Data : Environ Pollut. 2017 Dec 22 ;235:141-149. Epub 2017 Dec 22. PMID: 29276960

Article Published Date : Dec 21, 2017

Study Type : Human Study

Additional Links

Diseases : Attention Deficit Hyperactivity Disorder, Bisphenol Toxicity

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

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These findings suggest that the effects of environmental BPA exposure on hormone levels might be modified by smoking and BMI.Dec 31, 2016

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Pubmed Data : Reprod Toxicol. 2016 Dec ;66:93-98. Epub 2016 Oct 14. PMID: 27751756

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Inflammation, Oxidative Stress

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

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These results observed negative associations between bisphenol S and semen parameters, especially among overweight and obese men.Jul 30, 2019

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Pubmed Data : J Endocr Soc. 2019 Sep 1 ;3(9):1715-1726. Epub 2019 Jul 25. PMID: 31528831

Article Published Date : Aug 31, 2019

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Obesity

Additional Keywords : Increased Risk

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Obesogenic

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This highlighted the potential role of BPA in estrogen oxidation and oxidative stress in NAFLD patients.Jan 11, 2020

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Pubmed Data : Hum Exp Toxicol. 2018 Jan 1:960327118758150. Epub 2018 Jan 1. PMID: 29441827

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Diseases : Asthma, Bisphenol Toxicity

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

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Urinary bisphenol A levels are found to be associated with diabetes independent of traditional diabetes risk factors.Mar 12, 2014

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Pubmed Data : J Environ Health Sci Eng. 2014 Mar 13 ;12(1):64. Epub 2014 Mar 13. PMID: 24625016

Article Published Date : Mar 12, 2014

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Diabetes Mellitus: Type 2

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

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Pubmed Data : Mol Biol Rep. 2019 Feb 7. Epub 2019 Feb 7. PMID: 30734171

Article Published Date : Feb 06, 2019

Study Type : Human In Vitro

Additional Links

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A

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Exposure to BPA at environmentally relevant concentrations impairs germ cell development in first trimester human fetal testis.Dec 31, 2017

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Pubmed Data : PLoS One. 2015;10(7):e0133238. Epub 2015 Jul 29. PMID: 26222054

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Pubmed Data : Sci Rep. 2021 Jan 18 ;11(1):1650. Epub 2021 Jan 18. PMID: 33462300

Article Published Date : Jan 17, 2021

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures

Problem Substances : Bisphenol A , Bisphenol F, Bisphenol S

Adverse Pharmacological Actions : Immunotoxic

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Problem Substances : Bisphenol A

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A review on sources and health impacts of bisphenol A.Nov 18, 2019

Pubmed Data : Chemosphere. 2019 Mar 1 ;225:247-258. Epub 2019 Mar 1. PMID: 30877919

Article Published Date : Feb 28, 2019

Study Type : Insect Study

Additional Links

Diseases : Bisphenol Toxicity, Infertility: Female

Problem Substances : Bisphenol A , Pesticides

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Pubmed Data : Ecotoxicol Environ Saf. 2020 Oct 19 ;208:111476. Epub 2020 Oct 19. PMID: 33091778

Article Published Date : Oct 18, 2020

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Pubmed Data : Environ Pollut. 2020 May 29 ;265(Pt A):114880. Epub 2020 May 29. PMID: 32540565

Bisphenol A impairs cognitive function and 5-HT metabolism in adult male mice by modulating the microbiota-gut-brain axis.May 25, 2021

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Pubmed Data : Chemosphere. 2021 May 26 ;282:130952. Epub 2021 May 26. PMID: 34082316

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Article Published Date : Sep 27, 2019

Study Type : Animal Study

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Diseases : Bisphenol Toxicity

Additional Keywords : Demyelinating Diseases

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Neurotoxic

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Bisphenol A-induced alterations in different stages of spermatogenesis.Feb 28, 2021

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Pubmed Data : J Health Pollut. 2021 Mar ;11(29):210307. Epub 2021 Feb 25. PMID: 33815905

Article Published Date : Feb 28, 2021

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity

Problem Substances : Bisphenol A

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Bisphenol A-induced oxidative damage in the hepatic and cardiac tissues of rats: The modulatory role of sesame lignans.Dec 31, 2019

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Pubmed Data : Exp Ther Med. 2020 Jan ;19(1):33-44. Epub 2019 Nov 13. PMID: 31853270

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Sesame Seeds

Diseases : Bisphenol Toxicity

Pharmacological Actions : Cardioprotective, Hepatoprotective

Problem Substances : Bisphenol A

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Bisphenol AF and bisphenol F induce similar feminizing effects in chicken embryo testis as bisphenol A.Oct 02, 2020

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Pubmed Data : Neurotoxicology. 2019 03 ;71:31-38. Epub 2018 Dec 3. PMID: 30521821

Article Published Date : May 15, 2016

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Pubmed Data : Environ Toxicol. 2015 Nov 5. Epub 2015 Nov 5. PMID: 26537420

Article Published Date : Nov 04, 2015

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Cadmium Poisoning

Problem Substances : Bisphenol A , Cadmium

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BPA and its analogs BPB, BPF, and BPS different concentrations led to marked alterations in the development of the male reproductive system.Nov 30, 2019

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Pubmed Data : Hum Exp Toxicol. 2019 Dec ;38(12):1344-1365. PMID: 31514588

Article Published Date : Nov 30, 2019

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Male Reproductive Development Abnormalities, Prenatal Chemical Exposures

Problem Substances : Bisphenol A , Bisphenol F, Bisphenol S

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View the Evidence: 913 Abstracts with Bisphenol Toxicity Research

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BPA might be involved in the insulin-resistance and hyperandrogenism of polycystic ovary syndrome.Nov 29, 2017

early-life exposure to BPA may increase adiposity and circulating lipid levels in rodents.Oct 04, 2017

Prenatal and postnatal exposure to BPA was related to an increased risk of childhood asthma.Feb 28, 2021

The association of bisphenol A and phthalates with risk of breast cancer.Feb 28, 2021

This meta-analysis indicated that Bisphenol A exposure is positively associated with T2DM risk in humans.Nov 05, 2018

This study provides additional epidemiological evidence supporting an association between BPA and cardiovascular disease.Oct 13, 2020

This study suggested possible causality between BPA exposure and childhood obesity.Jul 14, 2019

High fetal bisphenol A exposure enhances IL22 secretion: A proinflammatory cytokine.Jan 01, 2021

Total BPA was detected in 93 % of this healthy infant population aged 3-15 months who are without known environmental exposure to BPA.Dec 04, 2012

"Urinary bisphenol A concentrations and their implications for human exposure in several Asian countries."Aug 15, 2011

A high fat diet and a low-dose BPA exposure during pregnancy increases mammary tumor incidence in offspring.May 08, 2017

Apoptotic microparticles mediate the association between bisphenol A and subclinical atherosclerosis in a young population.Aug 17, 2021

Assessment of bisphenol A levels in preschool children-Results of a human biomonitoring study in Ankara, TurkeySep 01, 2019

Association of bisphenol A or bisphenol S exposure with oxidative stress and immune disturbance among unexplained recurrent spontaneous abortion women.Sep 30, 2020

Association of urinary bisphenols and triclosan with thyroid function during early pregnancy.Jan 11, 2019

Association of urinary levels of bisphenols F and S used as bisphenol A substitutes with asthma and hay fever outcomes.Nov 21, 2019

Based on obtained results it can be hypothesized that BPA may induce adverse pregnancy outcomes by acting on endocannabinoid system.Mar 29, 2018

Bisphenol A acts as an endocrine disruptor in relation to serum thyroid and reproductive hormone levels in men from an infertility clinic. Feb 15, 2010

Bisphenol A and bisphenol S exposures during pregnancy and gestational age.Jul 21, 2019

Bisphenol A and its analogues in Chinese total diets: Contaminated levels and risk assessment.Dec 31, 2019

Bisphenol A diglycidyl ether exposure might enhance food sensitization in early childhood.Dec 25, 2018

Bisphenol A enhances systemic inflammatory response in patients with gut barrier translocation of dysbiotic microbiota products.Jun 30, 2021

Bisphenol A exposure and risk of thyroid nodules in Chinese women.Feb 26, 2019

Bisphenol A exposure and sperm ACHE hydroxymethylation in men.Jan 07, 2019

Bisphenol A exposure in relation to altered lipid profile and dyslipidemia among Chinese adults: A repeated measures study.Mar 15, 2020

Bisphenol A exposure through receipt handling and its association with insulin resistance among female cashiers.May 15, 2018

Bisphenol a exposure, DNA methylation, and asthma in children.Dec 31, 2019

Bisphenol A in 24 h urine and plasma samples of the German Environmental Specimen Bank from 1995 to 2009: A retrospective exposure evaluation.Oct 31, 2012

Bisphenol A may increase the risk of metabolic syndrome.Aug 21, 2019

Bisphenol A may play a role in the aetiopathogenesis of polycystic ovary syndrome in adolescent girls.Mar 31, 2015

Bisphenol A was detected above the detection limit in all samples in individuals affected by non-alcoholic fatty liver disease.Jun 04, 2017

Bisphenol A was found to influence serum C-reactive protein levels in this study. Jul 11, 2016

Bisphenol A, S, and F exposure, ESR1/2, CAT, and eNOS genetic polymorphisms, and the risk of hypertension.Aug 22, 2021

Bisphenol AF and bisphenol S might be potential risk factors of gestational diabetes mellitus.Dec 31, 2018

Bisphenol residues were detected at concentrations from 0.09 to 11.56 ng/mL in breast milk samples.Oct 16, 2018

Bisphenol S is present in the urine from the United States and seven Asian countriesMay 23, 2012

Bisphenol-A exposure and risk of breast and prostate cancer in the Spanish European Prospective Investigation into Cancer and Nutrition study.Aug 15, 2021

Bisphenol-A plasma levels are related to inflammatory markers, visceral obesity and insulin-resistance.May 28, 2015

Bisphenols accumulation in the white matter-enriched brain tissue could signify that they are able to cross the blood-brain barrier.May 28, 2018

BPA could be a factor in acne development and its severity. Aug 10, 2021

BPA could have a direct relationship with systemic inflammation regardless of obesity or insulin resistance.Oct 05, 2016

BPA exposure during pregnancy affects language and social behavior development in infants.Jun 05, 2020

BPA exposure during the second trimester may have adverse effect on blood glucose levels among subfertile women.Mar 31, 2017

BPA exposure exert negative effects on oocyte retrieval and embryo implantation in women undergoing IVF.Oct 20, 2019

BPA exposure is associated with dysregulation of HPA-axis function during pregnancy.Sep 14, 2016

BPA exposure may be associated with a reduction in Leydig cell capacity and decreased sperm counts in young men.Nov 16, 2017

BPA exposure might be associated with Pervasive Developmental Disorder-Not Otherwise Specified.Mar 08, 2016

BPA exposure to a dose considered safe by US regulators may alter glucose-stimulated insulin response in humans.Sep 30, 2018

BPA exposure was associated with alterations in the timing of pubertal development.Jul 26, 2017

BPA has a harmful effect on hemato-biochemical changes that occur during pregnancy.Jan 02, 2020

BPA is positively associated with generalized obesity, abdominal obesity, and insulin resistance in middle-aged and elderly Chinese adults.Nov 16, 2011

BPA may be an environmental cofactor of diabetes.Jul 08, 2019

BPA may have toxic effects on the female reproductive system in humans, as it does in animal models.Jan 10, 2017

BPA may increase oxidative stress resulting in mitochondrial dysfunction that affecting the behavior and functioning of ASDs children.Mar 31, 2018

BPA may play a major role in the pathogenesis of polycystic ovarian syndrome.Nov 30, 2017

BPA might increase the risk of breast cancer incidence.Sep 15, 2021

Canned food consumption was associated with higher total BPA.Jul 06, 2018

Canned food intake and urinary bisphenol a concentrations.Jul 26, 2019

Canned vegetable and fruit, canned pasta, and canned soup were associated with higher levels of urinary BPA concentrations.Jun 26, 2016

Case study: Is bisphenol S safer than bisphenol A in thermal papers?May 19, 2019

Chlorinated derivatives of bisphenol A and occurrence of myocardial infarction in patients with type 2 diabetes.Jul 30, 2019

Concentrations of Bisphenol A and Seven Other Phenols in Pooled Sera from 3-11 Year Old Children: 2001-2002 National Health and Nutrition Examination Survey.Nov 04, 2012

Contamination status of bisphenol A and its analogues in foodstuffs and the implications for dietary exposure on adult residents in Zhejiang Province.Sep 30, 2019

Dermal absorption of BPA leads to prolonged exposure and may lead to higher proportions of unconjugated BPA in systemic circulation.Jul 30, 2017

Dietary exposure to BPA from canned foods increases its serum concentrations in young women. Apr 27, 2017

Endocrine disruptors may have a greater effect on developing organs in young children or in the unborn child.Jul 13, 2017

Endocrine disruptors such as BPA could modify neuroendocrine, reproductive, and metabolic regulation favouring PCOS development in adolescents.Jun 19, 2019

Environmental exposure to phthalates and BPA may reduce circulating levels of total 25(OH)D in adults.Sep 19, 2016

Exposure assessment of bisphenols in Chinese women during pregnancy.Jun 09, 2019

Exposure of children to even low doses of BPA may adversely affect later liver function.Nov 16, 2017

Exposure to bisphenols and asthma morbidity among low-income urban children with asthma.Jul 20, 2020

Exposure to bisphenols and parabens during pregnancy and relations to steroid changes.Apr 30, 2018

Bisphenol Toxicity

View the Evidence:
913 Abstracts with Bisphenol Toxicity Research