Brain Inflammation

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171 Substances Researched for Brain Inflammation
NameACCKFocus
Curcumin2437Locked
Resveratrol1320Locked
Apigenin612Locked
Cannabidiol812Locked
Luteolin812Locked
Alpha-Lipoic Acid211Locked
Astaxanthin611Locked
Cannabinoids 811Locked
Frankincense211Locked
Ginsenosides610Locked
Probiotics110Locked
Yoghurt110Locked
Melatonin59Locked
Ashwagandha58Locked
Berberine48Locked
Flavonoids68Locked
Ginkgo biloba48Locked
Hesperidin48Locked
Huperzine58Locked
Gastrodin47Locked
EGCG (Epigallocatechin gallate)56Locked
Paeoniflorin36Locked
Silibinin36Locked
Tanshinone IIA46Locked
Vitamin C36Locked
Bee Venom35Locked
Blueberry35Locked
Ginger35Locked
Naringenin 35Locked
Palmitoylethanolamide 35Locked
Piperine35Locked
Polyphenols45Locked
Thymoquinone45Locked
6-Shogaol24Locked
Astragaloside24Locked
Baicalein24Locked
Citrus Peel 24Locked
Coconut Oil24Locked
Delta-tetrahydrocannabinol (THC)34Locked
Genistein24Locked
Hydrogen Water24Locked
Lycopene24Locked
Nettle24Locked
Rosmarinic acid24Locked
Sweet Potato: Purple24Locked
Tangeretin 24Locked
Theaflavins24Locked
Ume (Japanese apricot) 24Locked
Arctigenin23Locked
Beta-Caryophyllene23Locked
Betulinic acid23Locked
Catechols23Locked
DHA (Docosahexaenoic Acid)23Locked
Glycyrrhizin23Locked
Gotu Kola23Locked
Hemp Seed23Locked
Honokiol23Locked
Polyunsaturated Fatty Acids (PUFAs)23Locked
Punicalagin23Locked
Quercetin23Locked
Reishi Mushroom23Locked
Spirulina23Locked
Sulforaphane23Locked
Turmerones23Locked
Acorus calamus12Locked
Anthocyanins12Locked
Arginine12Locked
Bacopa22Locked
Bamboo12Locked
Bee Pollen12Locked
Berries: All12Locked
Bifidobacterium Longum 12Locked
Boron12Locked
Burdock12Locked
Carnosine12Locked
Chinese Skullcap 12Locked
Chokeberry12Locked
Choline12Locked
Chrysanthemum Indicum12Locked
Chrysin22Locked
Dandelion 22Locked
Diosmin 12Locked
Dopa bean12Locked
EPA (Eicosapentaenoic Acid)12Locked
Ellagic Acid12Locked
Endocannabinoids12Locked
Fermented Foods and Beverages12Locked
Ferulic acid12Locked
Fish Oil12Locked
Gardenia12Locked
Garlic22Locked
Gingerol 12Locked
Glucosamine12Locked
Grape Seed Extract12Locked
Hibiscus sabdariffa 12Locked
Krill12Locked
Lactobacillus helveticus12Locked
Lactobacillus probiotics12Locked
Lithium12Locked
Lupeol12Locked
Lychee12Locked
Magnesium12Locked
Magnolol12Locked
Modified Citrus Pectin 12Locked
Moxibustion12Locked
Neem12Locked
Nobiletin 12Locked
Oleuropein12Locked
Olive Oil12Locked
Parthenolide12Locked
Peony12Locked
Pomegranate22Locked
Purslane12Locked
Rice Bran22Locked
Rose 12Locked
Rosemary12Locked
Rutin12Locked
Selenium12Locked
Sesamol12Locked
St. Johns Wort12Locked
Tart Cherry12Locked
Theanine12Locked
Thymol12Locked
Urolithin A 12Locked
Walnut12Locked
Acacia catechu11Locked
Achillea fragrantissima11Locked
Agrimony11Locked
Arugula11Locked
Asiatic Acid11Locked
Benzyl isothiocyanate 11Locked
Bergamot11Locked
Butterbur11Locked
Cannabigerol 11Locked
Cannabinoids: Synthetic11Locked
Cannabis11Locked
Carnosic Acid11Locked
Carnosol11Locked
Cordyceps sinensis11Locked
Cysteine (see N-Acetylcysteine)11Locked
Diosgenin11Locked
Elderberry11Locked
Fisetin11Locked
Fucoidan11Locked
Fucoxanthin 11Locked
Garlic: Aged11Locked
Ginseng (Korean)11Locked
Goji11Locked
Green Tea11Locked
Gynostemma11Locked
Isothiocyanates11Locked
Knema laurina 11Locked
Maple Syrup11Locked
Matairesinol 11Locked
Oleanolic acid11Locked
Omega-3 Fatty Acids11Locked
Persimmon 11Locked
Pterostilbene11Locked
Puerarin11Locked
Pycnogenol (Pine Bark)11Locked
Red Wine Extract11Locked
Sembung Leaf11Locked
Toona sinensis 11Locked
Turmeric11Locked
Vanillin11Locked
Vitamin D11Locked
Vitexins11Locked
Wasabi11Locked
Watercress11Locked
Wine11Locked
Xanthohumol11Locked
27 Problem Substances Researched for Brain Inflammation
NameACCKFocus
Aluminum921Locked
Butyrophilin110Locked
Chlamydia Pneumoniae 110Locked
Cow Milk110Locked
Mercury110Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)110Locked
Streptococcal M Protein110Locked
Acrylamide 12Locked
Aluminum Chloride12Locked
Aspartame12Locked
Bisphenol A 12Locked
Dexamethasone12Locked
Energy Drinks12Locked
Fluoride12Locked
Fluoxetine (trade name Prozac) 12Locked
Glyphosate formulations12Locked
High Fructose Corn Syrup12Locked
Morphine12Locked
Nanoparticles12Locked
Roundup (herbicide)12Locked
Simvastatin12Locked
Sodium Fluoride12Locked
Sugar Sweetened Beverages12Locked
Thimerosal 12Locked
Amphetamine11Locked
Cadmium11Locked
Lead11Locked
8 Therapeutic Actions Researched for Brain Inflammation
NameACCKFocus
Exercise516Locked
Electroacupuncture36Locked
Hyperbaric Treatment36Locked
Laser Treatment: Low-Level36Locked
Acupuncture12Locked
Dietary Modification: Low Calorie Diet12Locked
Exercise: Endurance12Locked
Light-Emitting Diodes (LEDs) Therapy11Locked
5 Problematic Actions Researched for Brain Inflammation
NameACCKFocus
Electromagnetic Radiation: 1.8 GHz12Locked
Nanotechnology12Locked
Vaccination: HPV (Gardasil)12Locked
Vaccination: All11Locked
Vaccination: Yellow Fever11Locked

View the Evidence:
539 Abstracts with Brain Inflammation Research

[+]

11.8% of 110 sudden infant death cases examined in the study occurred in temporal association with hexavalent vaccines.Mar 01, 2014

Pubmed Data : Curr Med Chem. 2014 Mar ;21(7):941-6. PMID: 24083600
Article Published Date : Mar 01, 2014
Study Type : Human Study
Additional Links
Diseases : Brain Inflammation , Encephalitis, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hexavalent
[+]

Boswellic acids could be used to reduce peritumoral edema associated with primary and secondary brain tumors.Dec 14, 2011

Pubmed Data : J Pharm Biomed Anal. 2011 Dec 15 ;56(5):998-1005. Epub 2011 Jul 29. PMID: 21855244
Article Published Date : Dec 14, 2011
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Brain Edema, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Despite a "decrease" in measles and mumps encephalitis, hospital admissions for encephalitis of "unknown etiology" have increased substantially.Jan 01, 2017

Pubmed Data : Lancet Infect Dis. 2017 04 ;17(4):422-430. Epub 2017 Mar 2. PMID: 28259562
Article Published Date : Jan 01, 2017
Study Type : Human Study
Additional Links
Diseases : Brain Inflammation , Encephalitis
Anti Therapeutic Actions : Vaccination: All
[+]

Extracellular vesicles are increased in the serum of children with autism spectrum disorderAug 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2018 Aug 27 ;15(1):239. Epub 2018 Aug 27. PMID: 30149804
Article Published Date : Aug 26, 2018
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Brain Inflammation
Additional Keywords : Exosomes
[+]

Inflammation may influence glutamate metabolism to alter behaviour, leading to depressive symptoms.Nov 09, 2016

Pubmed Data : Curr Top Behav Neurosci. 2016 Nov 10. Epub 2016 Aug 10. PMID: 27830574
Article Published Date : Nov 09, 2016
Study Type : Human Study
Additional Links
Diseases : Brain Inflammation , Depressive Disorder, Inflammation
Additional Keywords : Risk Factors
[+]

Lipoic acid down-regulates inflammation in multiple sclerosis patients.Jan 01, 2010

Pubmed Data : PLoS One. 2010;5(9). Epub 2010 Sep 28. PMID: 20927401
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Brain Inflammation , Multiple Sclerosis
Pharmacological Actions : cAMP up-regulation, Interleukin-17 downregulation, Interleukin-6 Downregulation
[+]

Low-grade inflammation is associated with apathy indirectly via deep white matter lesions in community-dwelling older adults.Apr 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Apr 17 ;20(8). Epub 2019 Apr 17. PMID: 30999680
Article Published Date : Apr 16, 2019
Study Type : Human Study
Additional Links
Diseases : Brain Inflammation , Inflammation
Additional Keywords : Risk Factors
[+]

Milk and bacterial proteins may produce neuron-specific antigens in children with autism. Aug 01, 2002

Pubmed Data : J Neuroimmunol. 2002 Aug;129(1-2):168-77. PMID: 12161033
Article Published Date : Aug 01, 2002
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Autoimmune Diseases, Brain Inflammation
Additional Keywords : Molecular Mimicry
Problem Substances : Butyrophilin, Chlamydia Pneumoniae , Cow Milk, Streptococcal M Protein
Adverse Pharmacological Actions : Immunoreactive, Immunotoxic, Neurotoxic
[+]

Multi-strain probiotic supplementation seems to exert a positive effect on neuroinflammation and neurocognitive impairment in HIV-1 infected subjects.Nov 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Nov 21 ;9(11). Epub 2017 Nov 21. PMID: 29160817
Article Published Date : Nov 20, 2017
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, HIV Infections
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Neuroglial activation and neuroinflammation in the brain of patients with autism.Dec 31, 2004

Pubmed Data : Ann Neurol. 2005 Jan ;57(1):67-81. PMID: 15546155
Article Published Date : Dec 31, 2004
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Brain Inflammation
[+]

Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias.Dec 15, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurol Neurosurg Psychiatry. 2017 Dec 16. Epub 2017 Dec 16. PMID: 29248892
Article Published Date : Dec 15, 2017
Study Type : Human Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation , Dementia: Lewy Body
Additional Keywords : Alzheimer's disease, Brain Inflammation, Dementia: Lewy Body
[+]

The combined effects of yogurt and exercise in healthy adults: Implications for biomarkers of depression and cardiovascular diseases.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2018 Oct ;6(7):1968-1974. Epub 2018 Sep 7. PMID: 30349687
Article Published Date : Sep 30, 2018
Study Type : Human Study
Additional Links
Substances : Yoghurt
Diseases : Brain Inflammation , C-Reactive Protein, Cardiovascular Diseases, Depression
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The levels of blood mercury and inflammatory-related neuropeptides in the serum are correlated in children with autism spectrum disorder.May 31, 2016

Pubmed Data : Metab Brain Dis. 2016 Jun ;31(3):593-9. Epub 2016 Jan 6. PMID: 26738726
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Diseases : Autism, Brain Inflammation
Problem Substances : Mercury
[+]

The measles vaccine can induce encephalitis.Jan 19, 2017

Pubmed Data : Vaccine. 2017 12 19 ;35(52):7309-7311. Epub 2017 Nov 8. PMID: 29128384
Article Published Date : Jan 19, 2017
Study Type : Human Study
Additional Links
Diseases : Brain Inflammation , Encephalitis, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Measles, Vaccination: Mumps-Measles-Rubella (MMR)
[+]

The results suggest that aluminum-induced CRP may in part contribute to a pathophysiological state associated with a chronic systemic inflammation of the human vasculature.Jul 31, 2015

Pubmed Data : J Inorg Biochem. 2015 Aug 1. Epub 2015 Aug 1. PMID: 26265215
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Diseases : Brain Inflammation , C-Reactive Protein, Inflammation
Additional Keywords : Increased Risk
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

These findings suggest that predisposition to autoimmunity, and immune/inflammatory activation, may be associated with autistic regression.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dev Med Child Neurol. 2017 09 ;59(9):947-951. Epub 2017 Apr 6. PMID: 28383115
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Autoimmune Diseases, Brain Inflammation
[+]

This is the first study demonstrating inflammation within the neurocircuitry of OCD.Jul 31, 2017

Pubmed Data : JAMA Psychiatry. 2017 Aug 1 ;74(8):833-840. PMID: 28636705
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Diseases : Brain Inflammation , Obsessive-Compulsive Disorder
[+]

Mercury stimulates VEGF and IL-6 release from human mast cells which could disrupt the blood-brain-barrier and permit brain inflammation.Mar 11, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2010 Mar 11 ;7:20. Epub 2010 Mar 11. PMID: 20222982
Article Published Date : Mar 11, 2010
Study Type : Human In Vitro
Additional Links
Diseases : Autism, Autism Spectrum Disorders, Brain Inflammation
Additional Keywords : Blood Brain Barrier, Heavy Metals and Autism, Vaccine Research
Problem Substances : Mercury
Adverse Pharmacological Actions : Blood Brain Barrier Injury, Inflammatory, Interleukin-6 up-regulation, Vascular Endothelial Growth Factor C Up-Regulation
[+]

This demonstrates the broad neuroprotective action of apigenin against AD pathogenesis in a human disease model.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 ;6:31450. Epub 2016 Aug 12. PMID: 27514990
Article Published Date : Dec 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Apigenin
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

A case report of fatal encephalitis asssociated with the measles rubella vaccine.Dec 01, 2013

Pubmed Data : J Clin Virol. 2013 Dec ;58(4):737-40. Epub 2013 Oct 24. PMID: 24216323
Article Published Date : Dec 01, 2013
Study Type : Human: Case Report
Additional Links
Diseases : Brain Inflammation , Encephalitis
Anti Therapeutic Actions : Vaccination: Adult Rubella, Vaccination: All, Vaccination: Mumps-Measles-Rubella (MMR)
[+]

A case series of multiple sclerosis-like persistent inflammatory activity and encephalitis in the brain of hepatitis B vaccinees.Jul 22, 1999

Pubmed Data : Neurology. 1999 Jul 22 ;53(2):396-401. PMID: 10430433
Article Published Date : Jul 22, 1999
Study Type : Human: Case Report
Additional Links
Diseases : Brain Inflammation , Multiple Sclerosis
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
[+]

Encephalitis with seizures in 5 patients with confirmed mumps vaccine strain in cerebrospinal fluid.Feb 15, 2015

Pubmed Data : J Neurol Sci. 2015 Feb 15 ;349(1-2):226-8. Epub 2014 Dec 18. PMID: 25542078
Article Published Date : Feb 15, 2015
Study Type : Human: Case Report
Additional Links
Diseases : Brain Inflammation , Encephalitis
Anti Therapeutic Actions : Vaccination: All, Vaccination: Mumps
[+]

6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment.Oct 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:1523-1529. Epub 2018 Sep 5. PMID: 30257370
Article Published Date : Oct 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gingerol
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries.Jul 14, 2020

Pubmed Data : Eur J Pharmacol. 2020 Jul 15:173294. Epub 2020 Jul 15. PMID: 32681941
Article Published Date : Jul 14, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gingerol
Diseases : Brain Inflammation , Brain Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

6-Shogaol exerts neuroprotective effects on dopaminergic neurons in vitro and in vivo parkinson's disease models.Aug 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Pharmacol Sin. 2013 Sep ;34(9):1131-9. Epub 2013 Jul 1. PMID: 23811724
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : 6-Shogaol
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

6-shogaol may play a role in inhibiting glial cell activation and reducing memory impairment in animal models of dementia. Jun 19, 2014

Pubmed Data : Biochem Biophys Res Commun. 2014 Jun 20 ;449(1):8-13. Epub 2014 May 2. PMID: 24796668
Article Published Date : Jun 19, 2014
Study Type : Animal Study
Additional Links
Substances : 6-Shogaol
Diseases : Brain Inflammation , Dementia
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

A cecal slurry mouse model of sepsis leads to acute consumption of vitamin C in the brain.Mar 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Mar 26 ;12(4). Epub 2020 Mar 26. PMID: 32224930
Article Published Date : Mar 25, 2020
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Brain Inflammation , Sepsis, Vitamin C Deficiency
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Risk Factors
[+]

A combination of ginger and peony root may prevent memory impairment in AD by inhibiting Aβ accumulation and inflammation in the brain.Nov 29, 2015

Pubmed Data : J Alzheimers Dis. 2015 Nov 30. Epub 2015 Nov 30. PMID: 26639976
Article Published Date : Nov 29, 2015
Study Type : Transgenic Animal Study
Additional Links
Substances : Ginger, Peony
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
Additional Keywords : Plant Extracts
[+]

A combination of resveratrol and curcumin is effective against aluminum chloride-induced neuroinflammation in rats.Feb 06, 2017

Pubmed Data : J Alzheimers Dis. 2017 Feb 7. Epub 2017 Feb 7. PMID: 28222524
Article Published Date : Feb 06, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Aluminum Toxicity , Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
Problem Substances : Aluminum Chloride
[+]

A Spirulina diet given to lactating mothers can protect against neuroinflammation and decreased antioxidant defence in brain of suckling pups.Aug 28, 2016

Pubmed Data : Nutr Neurosci. 2016 Aug 29:1-11. Epub 2016 Aug 29. PMID: 27571388
Article Published Date : Aug 28, 2016
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

A. calamus prevented from memory deficits and stress through controlling oxidative stress and inflammation processes.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2018 ;9:85. Epub 2018 Oct 12. PMID: 30450168
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Acorus calamus
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

A20 as a novel target for the anti-neuroinflammatory effect of chrysin via inhibition of NF-κB signaling pathway.Dec 31, 2018

Pubmed Data : Brain Behav Immun. 2019 07 ;79:228-235. Epub 2019 Feb 7. PMID: 30738841
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Chrysin
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Absence of gut microbiota affects lipid metabolism in the prefrontal cortex of mice.Oct 06, 2019

Pubmed Data : Neurol Res. 2019 Oct 7:1-9. Epub 2019 Oct 7. PMID: 31587617
Article Published Date : Oct 06, 2019
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Dysbiosis
Additional Keywords : Gut-brain Axis
[+]

Acupuncture is an effective treatment for chronic overlapping pain conditions and provide insight into treatment response variability.Jul 03, 2018

Pubmed Data : J Pain. 2018 Jul 4. Epub 2018 Jul 4. PMID: 29981376
Article Published Date : Jul 03, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Chronic Pain
Therapeutic Actions : Acupuncture
Pharmacological Actions : Analgesics
[+]

Acute exposure to 900-MHz microwaves induces glial reactivity and biochemical modifications in the rat brain.Dec 01, 2004

Pubmed Data : Neurobiol Dis. 2004 Dec ;17(3):445-54. PMID: 15571980
Article Published Date : Dec 01, 2004
Study Type : Animal Study
Additional Links
Diseases : Brain: Microglial Activation, Brain Inflammation
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Adverse Pharmacological Actions : Neurotoxic
[+]

Acute neuroinflammation promotes cell responses to 1800 MHz GSM electromagnetic fields in the rat cerebral cortex.Sep 30, 2017

Pubmed Data : Neurotox Res. 2017 Oct ;32(3):444-459. Epub 2017 Jun 3. PMID: 28578480
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation
Anti Therapeutic Actions : Electromagnetic Radiation: 1.8 GHz
[+]

Addition of tart cherry to the diet may promote healthy aging or delay the onset of neurodegenerative diseases.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Age (Dordr). 2016 Dec ;38(5-6):393-404. Epub 2016 Aug 30. PMID: 27578256
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Tart Cherry
Diseases : Aging, Brain Inflammation , Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Administering curcumin may alleviate cerebral inflammation resulting from intracerebral hemorrhage.Mar 25, 2016

Pubmed Data : Neurosci Lett. 2016 Mar 26 ;620:74-82. Epub 2016 Mar 26. PMID: 27026486
Article Published Date : Mar 25, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-17 downregulation
[+]

Administration of synthetic 2-AG to mice after CHI led to significant reduction of brain oedema, better clinical recovery, reduced infarct volume and reduced hippocampal cell death compared with controls.Oct 03, 2001

Pubmed Data : Nature. 2001 Oct 4 ;413(6855):527-31. PMID: 11586361
Article Published Date : Oct 03, 2001
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Brain Edema, Brain Inflammation , Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Aerobic exercise significantly increases the chronic unpredictable mild stress-depressed mice hippocampus expression of miR-223.Apr 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2020 Apr 14 ;17(8). Epub 2020 Apr 14. PMID: 32295141
Article Published Date : Apr 13, 2020
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Depression
Therapeutic Actions : Exercise: Aerobic
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents
[+]

Aluminium, fluoride and a combination of aluminium-fluoride treatments caused an increase in brain lipid peroxidation products and reactive oxygen species formation.Feb 28, 2015

Pubmed Data : Pathophysiology. 2015 Mar ;22(1):39-48. Epub 2014 Dec 13. PMID: 25577494
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Brain Inflammation , Fluoride Toxicity , Neurodegenerative Diseases, Oxidative Stress
Additional Keywords : Increased Risk, Synergistic Toxicity
Problem Substances : Aluminum, Fluoride, Sodium Fluoride
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum can induce neuroinflammation and could lead to learning and memory deficits.Apr 30, 2016

Pubmed Data : Chemosphere. 2016 May ;151:289-95. Epub 2016 Mar 15. PMID: 26946116
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Brain Inflammation , Cognitive Decline/Dysfunction
Additional Keywords : aluminum, aluminum toxicity, Brain Inflammation, Cognitive Decline/Dysfunction
Problem Substances : Aluminum
Adverse Pharmacological Actions : Inflammatory
[+]

Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.Nov 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Nov 28 ;18(12). Epub 2017 Nov 28. PMID: 29182579
Article Published Date : Nov 27, 2017
Study Type : Animal Study
Additional Links
Substances : Krill
Diseases : Alzheimer's Disease, Brain: Oxidative Stress, Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents
[+]

Anti-inflammatory and anti-oxidant activity of Hidroxin in rotenone-induced Parkinson's disease.Sep 02, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Sep 3 ;9(9). Epub 2020 Sep 3. PMID: 32899274
Article Published Date : Sep 02, 2020
Study Type : Animal Study
Additional Links
Substances : Hydroxytyrosol
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Anti-neuroinflammatory effects of a food-grade phenolic-enriched maple syrup extract in a mouse model of Alzheimer's disease.Oct 03, 2019

Pubmed Data : Nutr Neurosci. 2019 Oct 4:1-10. Epub 2019 Oct 4. PMID: 31583972
Article Published Date : Oct 03, 2019
Study Type : Animal Study
Additional Links
Substances : Maple Syrup
Diseases : Alzheimer's Disease, Brain Inflammation
[+]

Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone.Oct 11, 2019

Pubmed Data : Physiol Behav. 2019 Oct 12 ;212:112699. Epub 2019 Oct 12. PMID: 31614158
Article Published Date : Oct 11, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Antioxidants, Interleukin-1 beta downregulation
[+]

Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.Jan 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lipids Health Dis. 2020 Jan 8 ;19(1):4. Epub 2020 Jan 8. PMID: 31915015
Article Published Date : Jan 07, 2020
Study Type : Animal Study
Additional Links
Substances : Polyunsaturated Fatty Acids (PUFAs)
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-10 downregulation
[+]

Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice.Apr 26, 2018

Pubmed Data : Metab Brain Dis. 2018 Apr 27. Epub 2018 Apr 27. PMID: 29704081
Article Published Date : Apr 26, 2018
Study Type : Animal Study
Additional Links
Substances : Nettle
Diseases : Anxiety, Brain Inflammation , Depression, Diabetic Complications
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antidepressant-like mechanism of honokiol in a rodent model of corticosterone-induced depression.Sep 29, 2020

Pubmed Data : J Integr Neurosci. 2020 Sep 30 ;19(3):459-467. PMID: 33070525
Article Published Date : Sep 29, 2020
Study Type : Animal Study
Additional Links
Substances : Honokiol
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation
[+]

Antidepressive effect of arctiin by attenuating neuroinflammation.Jan 04, 2020

Pubmed Data : ACS Chem Neurosci. 2020 08 5 ;11(15):2214-2230. Epub 2020 Jul 15. PMID: 32609480
Article Published Date : Jan 04, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Burdock
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Apigenin restored immune function and decreased neuroinflammation in an experimental autoimmune encephalomyelitis model. Jun 03, 2015

Pubmed Data : J Neuroimmune Pharmacol. 2015 Jun 4. Epub 2015 Jun 4. PMID: 26040501
Article Published Date : Jun 03, 2015
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Autoimmune Diseases, Brain Inflammation , Encephalomyelitis, Multiple Sclerosis: Relapsing-Remitting
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Gene Expression
[+]

Arctigenin may have anti-inflammatory and immunosuppressive properties via inhibiting Th17 cells.Oct 05, 2015

Pubmed Data : Mol Neurobiol. 2015 Oct 6. Epub 2015 Oct 6. PMID: 26440666
Article Published Date : Oct 05, 2015
Study Type : Animal Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Autoimmune Diseases, Brain Inflammation , Multiple Sclerosis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents
[+]

Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation.Sep 09, 2020

Pubmed Data : Br J Pharmacol. 2020 Sep 10. Epub 2020 Sep 10. PMID: 32964428
Article Published Date : Sep 09, 2020
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Artesunate may exert protective effects against cerebral ischemia/reperfusion injury.Apr 30, 2018

Pubmed Data : Mol Med Rep. 2018 May ;17(5):6639-6646. Epub 2018 Mar 1. PMID: 29512760
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Artesunate
Diseases : Brain Inflammation , Cerebral Ischemia, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Ashwagandha may serve as an effective dietary supplement for management of sleep deprivation induced stress and associated functional impairments.Dec 20, 2016

Pubmed Data : Mol Cell Biochem. 2016 Dec 21. Epub 2016 Dec 21. PMID: 28004351
Article Published Date : Dec 20, 2016
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Brain Inflammation , Insomnia, Sleep Disorders
Pharmacological Actions : Anti-Anxiety Agents, Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Ashwagandha treatment reversed the cytoplasmic mislocalization of hTDP-43 in spinal motor neurons and in brain.Dec 06, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurotherapeutics. 2016 Dec 7. Epub 2016 Dec 7. PMID: 27928708
Article Published Date : Dec 06, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Amyotrophic lateral sclerosis (ALS), Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Astaxanthin ameliorates lipopolysaccharide-induced neuroinflammation, oxidative stress and memory dysfunction.Feb 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Feb 18 ;17(2). Epub 2019 Feb 18. PMID: 30781690
Article Published Date : Feb 17, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury.Sep 18, 2018

Pubmed Data : Brain Res Bull. 2018 Sep 19. Epub 2018 Sep 19. PMID: 30243665
Article Published Date : Sep 18, 2018
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Inflammation , Spinal Cord Inflammation, Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astaxanthin attenuates neuroinflammation in status epilepticus.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2020 ;14:1651-1662. Epub 2020 Apr 30. PMID: 32431490
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Inflammation , Epilepsy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Astaxanthin exerts different anti-inflammatory effects in female and male brains.Jan 29, 2016

Pubmed Data : J Sci Food Agric. 2016 Jan 30 ;96(2):615-8. Epub 2015 Feb 25. PMID: 25678261
Article Published Date : Jan 29, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Aging, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation
[+]

Astaxanthin had an anti-depressant effect on diabetic mice.Dec 21, 2016

Pubmed Data : Brain Res. 2016 Dec 22. Epub 2016 Dec 22. PMID: 28017669
Article Published Date : Dec 21, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Inflammation , Depression, Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Prophylactic Agents
[+]

Astaxanthin suppresses the neurological disorders induced by the K+ channel blocker kaliotoxin.Apr 05, 2016

Pubmed Data : Inflamm Res. 2016 Apr 6. Epub 2016 Apr 6. PMID: 27052008
Article Published Date : Apr 05, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragalin exerted antidepressant-like action through SIRT1 signalling modulated NLRP3 inflammasome deactivation.Jan 19, 2020

Pubmed Data : ACS Chem Neurosci. 2020 05 20 ;11(10):1495-1503. Epub 2020 May 4. PMID: 32364698
Article Published Date : Jan 19, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids, Moringa oleifera
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents
[+]

Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice.May 23, 2018

Pubmed Data : Acta Pharmacol Sin. 2018 May 24. Epub 2018 May 24. PMID: 29795356
Article Published Date : May 23, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Brain Inflammation , Depressive Disorder
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragaloside IV protects dopaminergic neuron from neuroinflammation and oxidative stress.Sep 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 Oct ;75:105651. Epub 2019 Aug 8. PMID: 31401385
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Astragaloside might be a useful chemical in improving the spatial memory and relieving the oxidative stress and neuroinflammation in Alzheimer patients.Mar 29, 2018

Pubmed Data : Chin Med Sci J. 2018 Mar 30 ;33(1):29-37. PMID: 29620512
Article Published Date : Mar 29, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Alzheimer's Disease, Brain: Oxidative Stress, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Azadirachta indica ameliorates mouse hepatitis virus-induced neuroinflammatory demyelination.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Neurosci. 2020 ;14:116. Epub 2020 May 12. PMID: 32477069
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Neem
Diseases : Brain Inflammation , Hepatitis, Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents
[+]

B vitamins had the potential for treatment of neuroinflammation and neuroregeneration.Dec 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Dec 17 ;24(24). Epub 2019 Dec 17. PMID: 31861069
Article Published Date : Dec 16, 2019
Study Type : Animal Study
Additional Links
Substances : Pantothenic Acid (Vitamin B-5), Riboflavin (Vitamin B-2), Thiamine (B-1) , Vitamin B-12, Vitamin B-3 (Niacin), Vitamin B-6
Diseases : Brain Inflammation , Nerve Injuries, Neurodegenerative Diseases, Peripheral Nerve Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Baicalein is a promising novel analgesic agent for cancer-induced bone pain.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:973524. Epub 2015 Nov 15. PMID: 26649065
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Brain Inflammation , Cancer: Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalein may be effective in the treatment of Parkinson's disease through anti-neuroinflammation.Aug 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Sep ;50:38-47. Epub 2017 Jun 15. PMID: 28623717
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Bamboo extracts could be useful in treating HIV driven brain inflammation. Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J HIV AIDS. 2016 May ;2(3). Epub 2016 May 11. PMID: 27398410
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Bamboo
Diseases : Brain Inflammation , HIV Infections
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Bee pollen and propolis protect against neuroinflammation in the rodent model of autism. Nov 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Lipids Health Dis. 2019 Nov 16 ;18(1):200. Epub 2019 Nov 16. PMID: 31733650
Article Published Date : Nov 15, 2019
Study Type : Animal Study
Additional Links
Substances : Propolis: Bee
Diseases : Autism, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Bee pollen can be used safely to ameliorate oxidative stress, neuroinflammation, poor detoxification, and abnormal gut microbiota.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 ;16(1):120. Epub 2016 Apr 23. PMID: 27107819
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Bee Pollen
Diseases : Autistic Disorder, Brain Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Microbiota
[+]

Bee venom could be considered a potential therapeutic or preventive agent for PD and other neuroinflammatory associated disorders.Jul 27, 2016

Pubmed Data : Arch Pharm Res. 2016 Jul 28. Epub 2016 Jul 28. PMID: 27469335
Article Published Date : Jul 27, 2016
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Alzheimer's Disease, Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process.Jan 02, 2017

Pubmed Data : Biomed Pharmacother. 2017 Jan 3 ;87:200-208. Epub 2017 Jan 3. PMID: 28061403
Article Published Date : Jan 02, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Brain Inflammation , Epilepsy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Berberine attenuates experimental autoimmune encephalomyelitis in mice.Jan 01, 2010

Pubmed Data : PLoS One. 2010;5(10):e13489. Epub 2010 Oct 19. PMID: 20976070
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Blood-Brain-Barrier Disorders, Brain Inflammation , Multiple Sclerosis
Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Berberine could alleviate postoperative cognitive dysfunction by suppressing neuroinflammation in aged mice.Jun 30, 2016

Pubmed Data : Int Immunopharmacol. 2016 Jul 1 ;38:426-433. Epub 2016 Jul 1. PMID: 27376853
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Postoperative Recovery
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine could significantly improve the spatial learning and memory abilities of rats with vascular cognitive impairment. Jul 27, 2019

Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2019 Jul 28 ;35(4):359-362. PMID: 31701723
Article Published Date : Jul 27, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Brain: Oxidative Stress, Brain Inflammation , Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Berberine treatment improved short-term memory in hyperlipidemia.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Neurourol J. 2019 Nov ;23(Suppl 2):S102-110. Epub 2019 Nov 30. PMID: 31795609
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Brain Inflammation , Hyperlipidemia
Pharmacological Actions : Anti-Inflammatory Agents, Anticholesteremic Agents, Hypolipidemic
[+]

Betulinic acid restores hippocampal cAMP/cGMP and BDNF, improves cerebral blood flow and recovers memory deficits. May 16, 2018

Pubmed Data : Eur J Pharmacol. 2018 May 17 ;832:56-66. Epub 2018 May 17. PMID: 29778746
Article Published Date : May 16, 2018
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Dementia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Brain-derived neurotrophic factor modulator, Neuroprotective Agents
[+]

Bioactive components from garlic on brain resiliency against neuroinflammation and neurodegeneration.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2020 Feb ;19(2):1554-1559. Epub 2019 Dec 27. PMID: 32010338
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Brain Inflammation , Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Biochanin A has been shown to have neuroprotective effects in cerebral ischemia/reperfusion.Jan 14, 2015

Pubmed Data : J Neurol Sci. 2015 Jan 15 ;348(1-2):121-5. Epub 2014 Nov 18. PMID: 25466482
Article Published Date : Jan 14, 2015
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Brain Inflammation , Brain Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Biochanin A protects against angiotensin II-induced damage of dopaminergic neurons.Jan 11, 2019

Pubmed Data : Behav Pharmacol. 2019 12 ;30(8):700-711. PMID: 31703032
Article Published Date : Jan 11, 2019
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Brain Inflammation , Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Biochanin A reduces inflammatory injury and neuronal apoptosis following subarachnoid hemorrhage.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Neurol. 2018 ;2018:1960106. Epub 2018 Jun 3. PMID: 29971136
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Brain Inflammation , Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Bisphenol A exposure induces increased microglia and microglial related factors in the murine embryonic dorsal telencephalon and hypothalamus.Feb 28, 2018

Pubmed Data : Toxicol Lett. 2018 Mar 1 ;284:113-119. Epub 2017 Dec 14. PMID: 29248573
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain: Microglial Activation, Brain Inflammation , Prenatal Chemical Exposures
Problem Substances : Bisphenol A
[+]

Black chokeberry has protective effects against the development of Alzheimer's disease.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2018 Feb ;12(1):13-19. Epub 2018 Jan 15. PMID: 29399292
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Chokeberry
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, Prophylactic Agents
[+]

Blueberry attenuates microglial activation in the brain suggesting it may attenuate age-induced inflammation. Dec 14, 2009

Pubmed Data : Glia. 2009 Dec 14. PMID: 20014277
Article Published Date : Dec 14, 2009
Study Type : Animal Study
Additional Links
Substances : Blueberry
Diseases : Aging: Brain , Brain: Microglial Activation, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Boron could protect against acrylamide induced oxidative stress and inflammation. Jun 14, 2018

Pubmed Data : Food Chem Toxicol. 2018 Jun 15. Epub 2018 Jun 15. PMID: 29913234
Article Published Date : Jun 14, 2018
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Acrylamide-induced toxicity, Brain Inflammation , Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Hypolipidemic
Problem Substances : Acrylamide
[+]

Brain-selective mild hypothermia promotes long-term white matter integrity after ischemic stroke in mice.Jan 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : CNS Neurosci Ther. 2018 12 ;24(12):1275-1285. Epub 2018 Sep 16. PMID: 30295998
Article Published Date : Jan 11, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Brain Inflammation , Stroke: Ischemic
Therapeutic Actions : Cryotherapy
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Brazilian green propolis prevents cognitive decline into mild cognitive impairment in elderly people living at high altitude.Dec 31, 2017

Pubmed Data : J Alzheimers Dis. 2018 ;63(2):551-560. PMID: 29630549
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Propolis: Brazillian
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Butyrate and dietary soluble fiber improves neuroinflammation associated with aging.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2018 ;9:1832. Epub 2018 Aug 14. PMID: 30154787
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Butyrate, Fiber
Diseases : Aging, Brain Inflammation , Dysbiosis, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Epigenetic Modification
[+]

C. asiatica treatment helps to prevent cerebral damage and maintain near normal cerebral function in diabetes. Jun 24, 2020

Pubmed Data : Inflammopharmacology. 2020 Jun 25. Epub 2020 Jun 25. PMID: 32588370
Article Published Date : Jun 24, 2020
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Brain: Oxidative Stress, Brain Inflammation , Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Caffeic acid phenethyl ester reversed cadmium-induced cell death in hippocampus and cortex and subsequent cognitive disorders.Sep 30, 2020

Pubmed Data : Food Chem Toxicol. 2020 Oct ;144:111636. Epub 2020 Jul 30. PMID: 32739455
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester
Diseases : Brain Inflammation , Cadmium Poisoning
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
Problem Substances : Cadmium
[+]

Caffeine may abrogate lipopolysaccharide-induced oxidative stress and neuroinflammation.Nov 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2019 Nov 8 ;9(11). Epub 2019 Nov 8. PMID: 31717470
Article Published Date : Nov 07, 2019
Study Type : Animal Study
Additional Links
Substances : Caffeine
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Calorie restriction protects neural stem cells from age-related deficits in the subventricular zoneJan 07, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2019 Jan 8 ;11(1):115-126. PMID: 30622221
Article Published Date : Jan 07, 2019
Study Type : Animal Study
Additional Links
Diseases : Aging: Brain , Brain Inflammation
Therapeutic Actions : Dietary Modification: Low Calorie Diet
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Cannabidiol may have potential as a preventative treatment for Alzheimer's disease.Dec 31, 2013

Pubmed Data : J Alzheimers Dis. 2014 ;42(4):1383-96. PMID: 25024347
Article Published Date : Dec 31, 2013
Study Type : Transgenic Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Brain: Oxidative Stress, Brain Inflammation , Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis.Apr 30, 2009

Pubmed Data : Neurobiol Dis. 2009 May ;34(2):300-7. PMID: 19385063
Article Published Date : Apr 30, 2009
Study Type : Animal Study
Additional Links
Substances : Cannabinoids
Diseases : Aging, Aging: Brain , Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Calcium Channel Blockers, Neuritogenic, Neuroprotective Agents
[+]

Cannabinoids may have therapeutic value in neurodegenerative conditions by preventing and/or reducing neuroinflammation. Feb 22, 2007

Pubmed Data : Neuroscience. 2007 Feb 23 ;144(4):1516-22. Epub 2006 Dec 18. PMID: 17178196
Article Published Date : Feb 22, 2007
Study Type : Animal Study
Additional Links
Substances : Cannabinoids
Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Carnosic acid alleviates chlorpyrifos-induced oxidative stress and inflammation in mice cerebral and ocular tissues.Jan 21, 2020

Pubmed Data : Environ Sci Pollut Res Int. 2020 Jan 22. Epub 2020 Jan 22. PMID: 31965510
Article Published Date : Jan 21, 2020
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Brain: Oxidative Stress, Brain Inflammation , Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Problem Substances : Chlorpyrifos
[+]

Carnosic acid may represent a novel therapeutic strategy to treat metabolic disease induced brain injury.Jun 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Jul ;20(1):495-504. Epub 2019 May 27. PMID: 31180544
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Brain Inflammation , High Fat Diet
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Carnosine prevents Aβ-induced oxidative stress and inflammation in microglial cells.Jan 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2019 Jan 17 ;8(1). Epub 2019 Jan 17. PMID: 30658430
Article Published Date : Jan 16, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Physiol Pharmacol. 2020 Jan ;24(1):27-37. Epub 2020 Dec 20. PMID: 31908572
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Chamomile decoction mitigates high fat diet-induced anxiety-like behavior, neuroinflammation and cerebral ROS overload.Dec 13, 2020

Pubmed Data : Nutr Neurosci. 2020 Dec 14:1-12. Epub 2020 Dec 14. PMID: 33314994
Article Published Date : Dec 13, 2020
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Anxiety, Brain Inflammation , High Fat Diet, Obesity
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents
[+]

Chronic consumption of alcohol in combination with energy drinks causes an inflammatory response and oxidative stress.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:8725354. Epub 2016 Mar 16. PMID: 27069534
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Alcohol Toxicity , Brain Inflammation , Oxidative Stress
Problem Substances : Energy Drinks
[+]

Chronic consumption of γ-oryzanol can revert the LPS-induced cognitive and memory impairments by promoting hippocampal antioxidant and anti-inflammatory molecular responses.Mar 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Mar 29 ;11(4). Epub 2019 Mar 29. PMID: 30934852
Article Published Date : Mar 29, 2019
Study Type : Animal Study
Additional Links
Substances : Gamma-Oryzanol
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Chronic exposure to aspartame results in oxidative stress in the brain of albino rats, as well as methanol formation. Aug 31, 2012

Pubmed Data : J Biosci. 2012 Sep ;37(4):679-88. PMID: 22922192
Article Published Date : Aug 31, 2012
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Excitotoxicity , Lipid Peroxidation
Problem Substances : Aspartame
Adverse Pharmacological Actions : Neurotoxic
[+]

Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation.Aug 01, 2007

Pubmed Data : J Neurochem. 2007 Aug;102(3):761-72. Epub 2007 May 4. PMID: 17488274
Article Published Date : Aug 01, 2007
Study Type : Animal Study
Additional Links
Substances : Lithium
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Chronic T. gondii infection promotes neuroinflammation through cytokine networks and induces pathological progression of Alzheimer's disease.Aug 10, 2016

Pubmed Data : J Parasitol. 2016 Aug 11. Epub 2016 Aug 11. PMID: 27513205
Article Published Date : Aug 10, 2016
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation , Toxoplasma gondii Infection
Additional Keywords : Increased Risk
[+]

Chrysanthemum indicum might be an alternative and promising agent for the treatment of aging and age-associated brain and liver diseasesJan 01, 2019

Pubmed Data : J Ethnopharmacol. 2019 Jan 2. Epub 2019 Jan 2. PMID: 30610932
Article Published Date : Jan 01, 2019
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Indicum
Diseases : Aging: Brain , Brain Inflammation , Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chrysin prevents cognitive and hippocampal long-term potentiation deficits and inflammation in rat with cerebral hypoperfusion and reperfusion injury.May 31, 2019

Pubmed Data : Life Sci. 2019 Jun 1 ;226:202-209. Epub 2019 Apr 13. PMID: 30991061
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Brain Inflammation , Brain Ischemia, Cerebral Hypoperfusion, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chrysin restores MPTP induced neuroinflammation, oxidative stress and neurotrophic factors in an acute Parkinson's disease mouse model.Sep 13, 2019

Pubmed Data : Neurosci Lett. 2019 Sep 14 ;709:134382. Epub 2019 Jul 17. PMID: 31325581
Article Published Date : Sep 13, 2019
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Consumption of blueberries may reverse some age-related deficits in cognition.Feb 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Gerontol A Biol Sci Med Sci. 2019 Feb 17. Epub 2019 Feb 17. PMID: 30772901
Article Published Date : Feb 16, 2019
Study Type : Animal Study
Additional Links
Substances : Blueberry
Diseases : Aging: Brain , Brain Inflammation , Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin and piperine afforded a better neuroprotective effect compared to each of them alone.Nov 15, 2016

Pubmed Data : Inflammopharmacology. 2016 Nov 16. Epub 2016 Nov 16. PMID: 27853890
Article Published Date : Nov 15, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin, Piperine
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Brain Inflammation, CURCUMIN, Interleukin-1 beta downregulation, Natural Substance Synergy, Parkinson's disease, Piperine
[+]

Curcumin and piperine showed strong antioxidant and protective effect against QA-induced behavioural and neurological alteration.Jan 29, 2016

Pubmed Data : Pharmacology. 2016 Jan 30 ;97(3-4):151-160. Epub 2016 Jan 30. PMID: 26828892
Article Published Date : Jan 29, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin, Piperine
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

Curcumin can attenuate the downregulation of CISD2 in spinal cord injuries and LPS-treated astrocytes.Aug 07, 2015

Pubmed Data : Injury. 2015 Aug 8. Epub 2015 Aug 8. PMID: 26387034
Article Published Date : Aug 07, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Spinal Cord Injuries
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, MicroRNA modulator, Neuroprotective Agents
[+]

Curcumin is effective in attenuating glial activation and ameliorates cognitive deficits in chronic epilepsy.Jul 15, 2015

Pubmed Data : Neurochem Int. 2015 Jul 16. Epub 2015 Jul 16. PMID: 26190183
Article Published Date : Jul 15, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Epilepsy
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Curcumin may be beneficial in the treatment of acute stress induced anxiety and enhancement of memory function.May 31, 2015

Pubmed Data : Brain Res Bull. 2015 Jun ;115:1-8. Epub 2015 Apr 11. PMID: 25869755
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Anxiety Disorders, Brain Inflammation , Stress
Pharmacological Actions : Anti-Anxiety Agents, Antioxidants, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
[+]

Curcumin protects pre-oligodendrocytes from activated microglia, indicating it may play a role in protecting against preterm periventricular leukomalacia (PVL).Jun 21, 2010

Pubmed Data : Brain Res. 2010 Jun 21;1339:60-9. Epub 2010 Apr 24. PMID: 20403340
Article Published Date : Jun 21, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Preterm Periventricular Leukomalacia (PVL)
Pharmacological Actions : Apoptotic, Enzyme Inhibitors, Neuroprotective Agents
[+]

Curcumin treatment attenuates ischemic stroke-induced brain injury via activation of SIRT1.Nov 26, 2015

Pubmed Data : Brain Res Bull. 2015 Nov 27. Epub 2015 Nov 27. PMID: 26639783
Article Published Date : Nov 26, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Mitochondrial Dysfunction , Stroke: Attenuation/Recovery
Pharmacological Actions : Interleukin-6 Downregulation, Neuroprotective Agents, SIRT1 Activator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin treatment significantly improved the neurological status evaluated during 2 weeks after brain injury.Aug 31, 2013

Pubmed Data : Pharmacol Biochem Behav. 2013 Sep ;110:238-44. Epub 2013 Aug 7. PMID: 23932920
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Brain Injury: Traumatic, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Depressive-like phenotype evoked by lifelong nutritional omega-3 deficiency.Jan 23, 2020

Pubmed Data : Brain Behav Immun. 2020 Jan 24. Epub 2020 Jan 24. PMID: 31987923
Article Published Date : Jan 23, 2020
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Brain Inflammation , Depression, Omega-3 Fatty Acid Deficiency
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Increased Risk
[+]

DHA-rich fish oil and Tualang honey can be effective in lowering pro-inflammatory cytokine levels in the brains of rats under chronic stress conditions.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Taibah Univ Med Sci. 2019 Aug ;14(4):317-323. Epub 2019 Jul 23. PMID: 31488962
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid), Tualang Honey
Diseases : Brain Inflammation , Stress
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury.Aug 01, 2008

Pubmed Data : J Neurotrauma. 2008 Aug;25(8):975-83. PMID: 18665805
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Choline
Diseases : Brain Inflammation , Traumatic Brain Injury
[+]

Dietary curcumin ameliorates aging-related cerebrovascular dysfunction through the AMPK/uncoupling protein 2 pathway.Dec 31, 2012

Pubmed Data : Cell Physiol Biochem. 2013 ;32(5):1167-77. Epub 2013 Nov 11. PMID: 24335167
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Cerebrovascular Disorders, Ischemia, Neurodegenerative Diseases, Oxidative Stress, Stroke
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Neurorestorative
[+]

Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation.Jun 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microbiome. 2019 Jun 29 ;7(1):98. Epub 2019 Jun 29. PMID: 31255176
Article Published Date : Jun 28, 2019
Study Type : Animal Study
Additional Links
Substances : Essential Fatty Acids
Diseases : Brain Inflammation , Dysbiosis, High Fructose Diet, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Neuroprotective Agents
[+]

Diosmin could be considered as potential candidate for novel anti-Alzheimer's disease therapy.Jan 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroimmunol. 2016 10 15 ;299:98-106. Epub 2016 Sep 1. PMID: 27725131
Article Published Date : Jan 14, 2016
Study Type : Animal Study
Additional Links
Substances : Diosmin
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Dried peel powder of C. kawachiensis exerts anti-inflammatory and neuroprotective effects in the brain.Jul 31, 2018

Pubmed Data : Biosci Biotechnol Biochem. 2018 Aug ;82(8):1384-1395. Epub 2018 May 6. PMID: 29732953
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus Peel
Diseases : Brain Inflammation , Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Early hyperbaric oxygen treatment attenuates burn-induced neuro-inflammation.Jul 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Jul 27 ;19(8). Epub 2018 Jul 27. PMID: 30060489
Article Published Date : Jul 26, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Burns: Severe
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Echinacoside protects dopaminergic neurons.Aug 22, 2020

Pubmed Data : Brain Res Bull. 2020 Aug 23 ;164:55-64. Epub 2020 Aug 23. PMID: 32846198
Article Published Date : Aug 22, 2020
Study Type : Animal Study
Additional Links
Substances : Echinacea
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Effects of Hericium erinaceus mycelium extracts on the functional activity of purinoceptors and neuropathic pain.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:2890194. Epub 2020 May 13. PMID: 32508945
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Brain Inflammation , Neuropathic Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

EGCG can attenuate high-fat-induced hypothalamic inflammation.Oct 12, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Oct 13 ;20(20). Epub 2019 Oct 13. PMID: 31614951
Article Published Date : Oct 12, 2019
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

EGCG has a beneficial effect on impaired adult neurogenesis caused by lipopolysaccharide induced neuro-inflammation.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Physiol Pharmacol. 2016 Jan ;20(1):41-51. Epub 2015 Dec 31. PMID: 26807022
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Electro-acupuncture alleviates chronic unpredictable stress-induced depressive- and anxiety-like behaviour and neuroinflammation.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Mol Neurosci. 2018 ;11:149. Epub 2018 May 31. PMID: 29946236
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Depression
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-18 down-regulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Electroacupuncture alleviates postoperative cognitive dysfunction in aged rats.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:6421260. Epub 2017 Jun 8. PMID: 28684969
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Postoperative Recovery
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Electroacupuncture attenuates cognition impairment via anti-neuroinflammation in an Alzheimer’s disease animal modelDec 12, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2019 Dec 13 ;16(1):264. Epub 2019 Dec 13. PMID: 31836020
Article Published Date : Dec 12, 2019
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents
[+]

Electroacupuncture pre-treatment alleviates sepsis-induced brain injury by inhibition of microglial activation and attenuation of inflammation.Oct 18, 2016

Pubmed Data : Brain Res Bull. 2016 Oct 19 ;127:248-259. Epub 2016 Aug 19. PMID: 27771396
Article Published Date : Oct 18, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain: Microglial Activation, Brain Inflammation , Sepsis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Catalase Up-Regulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ellagic acid inhibits neuroinflammation and cognitive impairment induced by lipopolysaccharides.Aug 09, 2020

Pubmed Data : Neurochem Res. 2020 Aug 10. Epub 2020 Aug 10. PMID: 32779097
Article Published Date : Aug 09, 2020
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Ellagic acid prevents cognitive and hippocampal long-term potentiation deficits and brain inflammation in rat with traumatic brain injury.Feb 28, 2015

Pubmed Data : Life Sci. 2015 Mar 1 ;124:120-7. Epub 2015 Jan 28. PMID: 25637685
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Brain Inflammation , Memory Disorders, Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Emblica officinalis could be a promising therapeutic aid against aluminium-induced neurotoxicity.Jan 31, 2019

Pubmed Data : Neurotox Res. 2019 Feb ;35(2):318-330. Epub 2018 Sep 21. PMID: 30242626
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Amla Fruit
Diseases : Aluminum Toxicity , Brain Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
Problem Substances : Aluminum
[+]

Endurance exercise may exert neuroprotective effects by mitigating the production of pro-inflammatory cytokines.Mar 15, 2016

Pubmed Data : J Neuroendocrinol. 2016 Mar 16. Epub 2016 Mar 16. PMID: 26991447
Article Published Date : Mar 15, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , High Fat Diet
Therapeutic Actions : Exercise: Endurance
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

EPA and GLA attenuate interleukin-1 beta-induced brain inflammation in rats. May 01, 2008

Pubmed Data : J Nutr. 2008 May;138(5):954-63. PMID: 18424607
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : EPA (Eicosapentaenoic Acid)
Diseases : Brain Inflammation
Pharmacological Actions : Interleukin-1 beta downregulation
[+]

Eriodictyol attenuates LPS-induced neuroinflammation, amyloidogenesis, and cognitive impairments.Oct 02, 2018

Pubmed Data : J Agric Food Chem. 2018 Oct 3 ;66(39):10205-10214. Epub 2018 Sep 21. PMID: 30208700
Article Published Date : Oct 02, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Alzheimer's Disease, Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Exercise three times a week was effective at reversing serum and brain RANTES and MCP-1 expression to the levels of controls.Dec 31, 2015

Pubmed Data : Neurosci Lett. 2016 Jan 1 ;610:165-70. Epub 2015 Nov 4. PMID: 26547034
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Dose Response, Risk Reduction
[+]

Exposure to ambient dusty particulate matter impairs spatial memory and hippocampal LTP by increasing brain inflammation and oxidative stress.Dec 20, 2019

Pubmed Data : Life Sci. 2019 Dec 21:117210. Epub 2019 Dec 21. PMID: 31874166
Article Published Date : Dec 20, 2019
Study Type : Animal Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Brain Inflammation , Cognitive Decline/Dysfunction, Memory Disorders
Additional Keywords : Risk Factors
[+]

Extracts of R. officinalis and rosmarinic acid through modulating neuro-inflammation might be potential candidates in treating neuropathic pain.Dec 21, 2016

Pubmed Data : Biomed Pharmacother. 2016 Dec 22 ;86:441-449. Epub 2016 Dec 22. PMID: 28012923
Article Published Date : Dec 21, 2016
Study Type : Animal Study
Additional Links
Substances : Rosemary, Rosmarinic acid
Diseases : Brain Inflammation , Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

F. mume is a potentially valuable drug or nutraceutical for the treatment of vascular dementia.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2016 Feb ;19(2):196-204. Epub 2015 Dec 29. PMID: 26714236
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Ume (Japanese apricot)
Diseases : Brain Inflammation , Cerebral Hypoperfusion, Dementia
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

F. mume is potentially an effective therapeutic for the treatment of vascular dementia.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 ;15:125. Epub 2015 Apr 22. PMID: 25898017
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Ume (Japanese apricot)
Diseases : Brain Inflammation , Brain Ischemia, Cerebral Hypoperfusion
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Phytotherapy
[+]

Fermentation enhances Ginkgo biloba protective role on gamma-irradiation induced inflammatory gene expression and stress hormones in rat brain.Mar 03, 2016

Pubmed Data : J Photochem Photobiol B. 2016 Mar 4 ;158:154-163. Epub 2016 Mar 4. PMID: 26974576
Article Published Date : Mar 03, 2016
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Ginkgo biloba
Diseases : Brain Inflammation , Chemotherapy and Radiation Toxicity
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Radioprotective
[+]

Ferulic acid inhibits neuro-inflammation in mice exposed to chronic unpredictable mild stress.Mar 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Apr ;45:128-134. Epub 2017 Feb 14. PMID: 28213267
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Ferulic acid
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, NF-kappaB Inhibitor
Problem Substances : Fluoxetine (trade name Prozac)
[+]

Fisetin may be developed as a potential nutritional target for the prevention of lead-induced neurotoxicity.Sep 16, 2019

Pubmed Data : Food Chem Toxicol. 2019 Sep 17 ;134:110824. Epub 2019 Sep 17. PMID: 31539617
Article Published Date : Sep 16, 2019
Study Type : Animal Study
Additional Links
Substances : Fisetin
Diseases : Brain Inflammation , Lead Poisoning
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Lead
[+]

Fish oil supplementation attenuates cognitive impairment by inhibiting neuroinflammation in STZ-induced diabetes.Aug 03, 2020

Pubmed Data : Aging (Albany NY). 2020 Aug 4 ;12. Epub 2020 Aug 4. PMID: 32756005
Article Published Date : Aug 03, 2020
Study Type : Animal Study
Additional Links
Substances : Fish Oil
Diseases : Brain Inflammation , Diabetes: Cognitive Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Formononetin could improve the cognitive function by inhibiting neuroinflammation.Aug 06, 2019

Pubmed Data : CNS Neurol Disord Drug Targets. 2019 Aug 7. Epub 2019 Aug 7. PMID: 31389320
Article Published Date : Aug 06, 2019
Study Type : Animal Study
Additional Links
Substances : Formononetin
Diseases : Alzheimer's Disease, Brain Inflammation , High Fat Diet
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gallic acid attenuated lipopolysaccharide-induced neuroinflammation.Dec 11, 2019

Pubmed Data : Mol Neurobiol. 2019 Dec 12. Epub 2019 Dec 12. PMID: 31832973
Article Published Date : Dec 11, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Gardasil via its Al adjuvant and HPV antigens has the ability to trigger neuroinflammation and autoimmune reactions.Jul 15, 2016

Pubmed Data : Immunol Res. 2016 Jul 16. Epub 2016 Jul 16. PMID: 27421722
Article Published Date : Jul 15, 2016
Study Type : Animal Study
Additional Links
Diseases : Autoimmune Diseases, Brain Inflammation
Anti Therapeutic Actions : Vaccination: HPV (Gardasil)
[+]

Gastrodin ameliorates depression-like behaviors and up-regulates proliferation of hippocampal-derived neural stem cells.May 31, 2014

Pubmed Data : Behav Brain Res. 2014 Jun 1 ;266:153-60. Epub 2014 Mar 5. PMID: 24613238
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Gastrodin can significantly relieve the Tourette syndrome induced by DOI in rats.Feb 19, 2019

Pubmed Data : J Biochem Mol Toxicol. 2019 Feb 20:e22302. Epub 2019 Feb 20. PMID: 30790395
Article Published Date : Feb 19, 2019
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Brain Inflammation , Tourette Syndrome
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model.Feb 14, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2012 Feb 15 ;7(5):325-31. PMID: 25774170
Article Published Date : Feb 14, 2012
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Genipin, a compound found within gardenia fruit, inhibits microglial activation in a mouse model of brain inflammation. Feb 01, 2010

Pubmed Data : Int Immunopharmacol. 2010 Feb 1. Epub 2010 Feb 1. PMID: 20123040
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Gardenia
Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Genistein attenuates acute cerebral ischemic damage. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2020 ;12:153. Epub 2020 Jun 17. PMID: 32625078
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Brain Inflammation , Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Genistein is able to regulate the gut microbiota, reducing metabolic endotoxemia and decreasing the neuroinflammatory response in a high fat diet.Dec 31, 2017

Pubmed Data : Mol Nutr Food Res. 2018 08 ;62(16):e1800313. Epub 2018 Jul 29. PMID: 29979819
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Brain Inflammation , High Fat Diet
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Genistein supplementation alleviated neuroinflammation and peripheral and brain insulin resistance.Oct 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Oct 31 ;8(11). Epub 2016 Oct 31. PMID: 27809235
Article Published Date : Oct 30, 2016
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Brain Inflammation , High Fat Diet, Insulin Resistance
Pharmacological Actions : Neuroprotective Agents
[+]

Ginger inhibits micoglial cell activiation associated with brain inflammation. Jun 01, 2009

Pubmed Data : Food Chem Toxicol. 2009 Jun;47(6):1190-7. Epub 2009 Feb 20. PMID: 19233241
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Brain: Microglial Activation, Brain Inflammation , Inflammation, Lipopolysaccharide-Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin Antagonists
[+]

Ginkgetin can significantly reduce plasma Aβ levels by 59% and Aβ plaque by 51% in the brain of transgenic mice.Dec 31, 2015

Pubmed Data : J Prev Alzheimers Dis. 2016 ;3(1):24-29. PMID: 29214278
Article Published Date : Dec 31, 2015
Study Type : Transgenic Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Neuroprotective Agents
[+]

Ginkgo biloba extract has potential therapeutic effects in relieving depressive status of patients with heart failure.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2019 ;15:3041-3050. Epub 2019 Oct 29. PMID: 31754303
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Brain Inflammation , Depression, Heart Failure
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginkgo biloba extract has specific neuroprotective effects that may be useful for the treatment of chronic cerebral hypoperfusion.Nov 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2016 Nov 15 ;23(12):1356-1364. Epub 2016 Aug 1. PMID: 27765355
Article Published Date : Nov 14, 2016
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Brain Inflammation , Cerebral Hypoperfusion
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Ginkgo biloba extract improves cognitive function and regulates inflammatory responses in the APP/PS1 mouse.Jul 31, 2016

Pubmed Data : Exp Gerontol. 2016 Aug ;81:92-100. Epub 2016 May 22. PMID: 27220811
Article Published Date : Jul 31, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress.May 24, 2020

Pubmed Data : Behav Brain Res. 2020 May 25:112710. Epub 2020 May 25. PMID: 32464121
Article Published Date : May 24, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antidepressive Agents
[+]

Ginsenoside has an anti-neuroinflammation effect in a rat model of Alzheimer disease.Jan 03, 2011

Pubmed Data : Neurosci Lett. 2011 Jan 3;487(1):70-2. Epub 2010 Oct 7. PMID: 20933058
Article Published Date : Jan 03, 2011
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2019 Oct ;43(4):499-507. Epub 2017 Jul 25. PMID: 31695559
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain Inflammation , Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Neuroprotective Agents
[+]

Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2019 Oct ;14(10):1814-1822. PMID: 31169200
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Ginsenoside Rg1 may have protective effects on neuroinflammation and neuronal injury induced by chronic glucocorticoids exposure.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2017 Oct ;40(4):1134-1142. Epub 2017 Aug 9. PMID: 28849171
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
Problem Substances : Dexamethasone
[+]

Ginsenoside Rg3 alleviates lipopolysaccharide-induced learning and memory impairments. Sep 29, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2013 Sep 30 ;21(5):381-90. PMID: 24244826
Article Published Date : Sep 29, 2013
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginsenoside Rg3 attenuates microglia activation following systemic lipopolysaccharide treatment in mice.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2012 ;35(9):1546-52. PMID: 22975507
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia/reperfusion injury.Nov 15, 2010

Pubmed Data : Glia. 2010 Nov 15 ;58(15):1881-92. PMID: 20737476
Article Published Date : Nov 15, 2010
Study Type : Animal Study
Additional Links
Substances : Glucosamine
Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions : Enzyme Inhibitors, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Glycyrrhizin protects mice against experimental autoimmune encephalomyelitis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2018 ;9:1518. Epub 2018 Jul 2. PMID: 30013568
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Glycyrrhizin
Diseases : Brain Inflammation , Encephalomyelitis, Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Gotu Kola protected against sleep deprivation-induced anxiety-like behaviour, oxidative damage and neuroinflammation in mice.Feb 04, 2016

Pubmed Data : Phytother Res. 2016 Feb 5. Epub 2016 Feb 5. PMID: 26848139
Article Published Date : Feb 04, 2016
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Anxiety Disorders, Brain Inflammation , Oxidative Stress, Sleep Disorders
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Gut bacteria regulate movement disorders in mice and suggest that alterations in the human microbiome represent a risk factor for PD.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell. 2016 Dec 1 ;167(6):1469-1480.e12. PMID: 27912057
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Dysbiosis, Parkinson's Disease
Additional Keywords : Microbiota, Risk Factors
[+]

H. sabdariffa is a potent anti-inflammatory substance that prevents impairments in spatial memory consolidation.Oct 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kobe J Med Sci. 2018 Oct 15 ;64(2):E73-E83. Epub 2018 Oct 15. PMID: 30381729
Article Published Date : Oct 14, 2018
Study Type : Animal Study
Additional Links
Substances : Hibiscus sabdariffa
Diseases : Brain Inflammation , Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Hericium erinaceus mycelium may be a potential health-promoting supplement for minimizing the progression of aging and obesity-induced neurodegeneration.Apr 30, 2019

Pubmed Data : J Med Food. 2019 May ;22(5):469-478. PMID: 31084539
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Lion's Mane (Hericium Erinaceus)
Diseases : Aging, Brain Inflammation , High Fat Diet, High Sugar Diet, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Neuritogenic, Neuroprotective Agents
[+]

Hesperidin attenuates depression-related symptoms in mice with mild traumatic brain injury.Nov 14, 2018

Pubmed Data : Life Sci. 2018 Nov 15 ;213:198-205. Epub 2018 Oct 21. PMID: 30352242
Article Published Date : Nov 14, 2018
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Hesperidin
Diseases : Brain Inflammation , Brain Injury: Traumatic, Depression, Oxidative Stress
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hesperidin could reduce the incidence and severity of Multiple sclerosis.Nov 25, 2016

Pubmed Data : J Neuroimmunol. 2016 Nov 26. Epub 2016 Nov 26. PMID: 27912911
Article Published Date : Nov 25, 2016
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Brain Inflammation , Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

HFCS-55, negatively impacts hippocampal function, metabolic outcomes, and neuroinflammation when consumed in excess during the adolescent period of development.Jan 31, 2015

Pubmed Data : Hippocampus. 2015 Feb ;25(2):227-39. Epub 2014 Oct 3. PMID: 25242636
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Learning disorders
Additional Keywords : Adolescent Development
Problem Substances : High Fructose Corn Syrup
Adverse Pharmacological Actions : Inflammatory
[+]

High selenium yeast mitigates aluminum-induced cerebral inflammation.Jul 15, 2018

Pubmed Data : Biometals. 2018 Jul 16. Epub 2018 Jul 16. PMID: 30014352
Article Published Date : Jul 15, 2018
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Aluminum Toxicity , Brain Inflammation
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Hippocampal derangements triggered by high fat-high fructose diet feeding were effectively curtailed by apigenin.Feb 22, 2017

Pubmed Data : Biomed Pharmacother. 2017 Feb 23 ;89:323-331. Epub 2017 Feb 23. PMID: 28237914
Article Published Date : Feb 22, 2017
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Brain Inflammation , High Fat Diet, High Fructose Diet
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Honokiol attenuates the memory impairments, oxidative stress, neuroinflammation, and GSK-3β activation in vascular dementia rats.Jul 15, 2019

Pubmed Data : J Alzheimers Dis. 2019 Jul 16. Epub 2019 Jul 16. PMID: 31322570
Article Published Date : Jul 15, 2019
Study Type : Animal Study
Additional Links
Substances : Honokiol
Diseases : Brain: Oxidative Stress, Brain Inflammation , Dementia
Pharmacological Actions : Neuroprotective Agents
[+]

Honokiol may be a potential therapeutic approach for Alzheimer's disease.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Exp Ther. 2018 Sep ;366(3):470-478. Epub 2018 Jul 10. PMID: 29991481
Article Published Date : Aug 31, 2018
Study Type : Transgenic Animal Study
Additional Links
Substances : Honokiol
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury.Jan 11, 2017

Pubmed Data : Metab Brain Dis. 2017 12 ;32(6):1861-1869. Epub 2017 Jul 26. PMID: 28748496
Article Published Date : Jan 11, 2017
Study Type : Animal Study
Additional Links
Substances : Huperzine
Diseases : Brain Inflammation , Brain Injury: Traumatic, Learning disorders, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion.Mar 01, 2010

Pubmed Data : J Neurosci Res. 2010 Mar;88(4):807-15. PMID: 19795377
Article Published Date : Mar 01, 2010
Study Type : Animal Study
Additional Links
Substances : Huperzine
Diseases : Brain Inflammation , Cerebral Hypoperfusion, Cognitive Decline/Dysfunction
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function.Sep 18, 2016

Pubmed Data : Neurosci Lett. 2016 Sep 19 ;631:70-8. Epub 2016 Jul 9. PMID: 27400829
Article Published Date : Sep 18, 2016
Study Type : Animal Study
Additional Links
Substances : Huperzine
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Sepsis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
[+]

Hydrogen rich water could exert a neuroprotective effect against traumatic brain injury and attenuate inflammation.Apr 14, 2016

Pubmed Data : Brain Res. 2016 Apr 15 ;1637:1-13. Epub 2016 Jan 26. PMID: 26826009
Article Published Date : Apr 14, 2016
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Brain Inflammation , Brain Injury: Traumatic, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-10 downregulation, Neuroprotective Agents
[+]

Hydrogen-rich water had beneficial effects on depressive-like behaviour and may be mediated by suppression of the inflammasome activation. Mar 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 Mar 30 ;6:23742. Epub 2016 Mar 30. PMID: 27026206
Article Published Date : Mar 29, 2016
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Brain: Oxidative Stress, Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation
[+]

Hyperbaric oxygen therapy treatment may ameliorate TBI-induced depression-like behaviour in rats by attenuating neuro-inflammation.Jan 04, 2017

Pubmed Data : World Neurosurg. 2017 Jan 5. Epub 2017 Jan 5. PMID: 28065873
Article Published Date : Jan 04, 2017
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hypothalamic inflammation was susceptible to exercise and diet.Jun 08, 2020

Pubmed Data : Aging (Albany NY). 2020 Jun 9 ;12. Epub 2020 Jun 9. PMID: 32518216
Article Published Date : Jun 08, 2020
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Memory Disorders
Therapeutic Actions : Exercise: Swimming
Pharmacological Actions : Neuroprotective Agents
[+]

Inhibitory effects of walnut peptides on neuroinflammation and oxidative stress in lipopolysaccharide-induced cognitive impairment.Feb 25, 2020

Pubmed Data : J Agric Food Chem. 2020 Feb 26 ;68(8):2381-2392. Epub 2020 Feb 18. PMID: 32037817
Article Published Date : Feb 25, 2020
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Isoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity.Jan 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Neurosci. 2019 08 6 ;20(1):41. Epub 2019 Aug 6. PMID: 31387531
Article Published Date : Jan 05, 2019
Study Type : Animal Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Isoliquiritigenin pre-treatment plays neuroprotective and anti-inflammatory roles in kainic acid-induced epileptogenesis.Apr 28, 2019

Pubmed Data : Inflammopharmacology. 2019 Apr 29. Epub 2019 Apr 29. PMID: 31037573
Article Published Date : Apr 28, 2019
Study Type : Animal Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Brain Inflammation , Epilepsy
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

It was found that ethylmercury caused abnormal neurogenic inflammatory reactions and alterations in the neuroimmune cells.May 09, 2018

Pubmed Data : Drug Chem Toxicol. 2018 May 10:1-11. Epub 2018 May 10. PMID: 29745770
Article Published Date : May 09, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation
Problem Substances : Thimerosal
Adverse Pharmacological Actions : Inflammatory
[+]

JNK1 inhibition by Licochalcone A leads to neuronal protection against excitotoxic insults derived of kainic acid.Jan 14, 2018

Pubmed Data : Neuropharmacology. 2018 03 15 ;131:440-452. Epub 2017 Oct 28. PMID: 29111385
Article Published Date : Jan 14, 2018
Study Type : Animal Study
Additional Links
Substances : Licorice
Diseases : Brain Inflammation , Inflammation, Neurodegenerative Diseases, Oxidative Stress, Seizures
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Kefir ameliorates hypertension via gut-brain mechanisms in spontaneously hypertensive rats.Dec 11, 2019

Pubmed Data : J Nutr Biochem. 2019 Dec 12 ;77:108318. Epub 2019 Dec 12. PMID: 31923755
Article Published Date : Dec 11, 2019
Study Type : Animal Study
Additional Links
Substances : Kefir
Diseases : Brain Inflammation , Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Gastrointestinal Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Korean Red Ginseng alleviates neuroinflammation and promotes cell survival.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2020 Jul ;44(4):593-602. Epub 2019 May 24. PMID: 32617039
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke.Feb 01, 2008

Pubmed Data : Shock. 2008 Feb;29(2):212-6. PMID: 17693925
Article Published Date : Feb 01, 2008
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Brain Inflammation , Heat Stroke
Pharmacological Actions : Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Long-term resveratrol treatment confers neuroprotection against cerebral vascular dysfunction during nutrient stress.Apr 08, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2016 Apr 9. Epub 2016 Apr 9. PMID: 27070252
Article Published Date : Apr 08, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Brain Inflammation , High Fat Diet, High Sugar Diet, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Low-level laser irradiation could represent a new promising therapeutic strategy for Alzheimer's disease.Dec 31, 2016

Pubmed Data : Neurobiol Aging. 2017 Jan ;49:165-182. Epub 2016 Oct 11. PMID: 27815990
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation , Mitochondrial Dysfunction
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Low-level laser therapy ameliorates disease progression in a mouse model of multiple sclerosis.Feb 29, 2016

Pubmed Data : Autoimmunity. 2016 Mar ;49(2):132-42. Epub 2015 Dec 24. PMID: 26703077
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Multiple Sclerosis
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Lupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection.Apr 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 May ;70:302-312. Epub 2019 Mar 7. PMID: 30852286
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Lupeol
Diseases : Alzheimer's Disease, Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Luteolin inhibits LPS-induced IL-6 production in the brain by inhibiting the JNK signaling pathway and activation of AP-1 in microglia and may be useful for mitigating neuroinflammation.May 26, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2008 May 27 ;105(21):7534-9. Epub 2008 May 19. PMID: 18490655
Article Published Date : May 26, 2008
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Luteolin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, C-Jun N-Terminal Kinases (JNK) Modulator, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome.Aug 04, 2020

Pubmed Data : Biomed Pharmacother. 2020 Aug 5 ;130:110575. Epub 2020 Aug 5. PMID: 32768883
Article Published Date : Aug 04, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lychee, Polyphenols
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Lycopene alleviates DSS-induced colitis and behavioral disorders via mediating microbes-gut-brain axis balance.Mar 11, 2020

Pubmed Data : J Agric Food Chem. 2020 Mar 12. Epub 2020 Mar 12. PMID: 32162923
Article Published Date : Mar 11, 2020
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Brain Inflammation , Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents
Additional Keywords : Gut-brain Axis
[+]

Lycopene attenuates aluminum-induced hippocampal lesions by inhibiting oxidative stress-mediated inflammation.Mar 31, 2019

Pubmed Data : J Inorg Biochem. 2019 Apr ;193:143-151. Epub 2019 Feb 1. PMID: 30743053
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Aluminum Toxicity , Brain Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum
[+]

Lycopene might be a nutritional preventive strategy in neuroinflammation-related diseases such as Alzheimer's disease.Feb 01, 2018

Pubmed Data : J Nutr Biochem. 2018 Feb 2 ;56:16-25. Epub 2018 Feb 2. PMID: 29454265
Article Published Date : Feb 01, 2018
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Alzheimer's Disease, Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nrf2 activation
[+]

Lycopene supplementation attenuates oxidative stress, neuroinflammation, and cognitive impairment in aged mice.Mar 05, 2018

Pubmed Data : J Agric Food Chem. 2018 Mar 6. Epub 2018 Mar 6. PMID: 29509007
Article Published Date : Mar 05, 2018
Study Type : Animal Study
Additional Links
Substances : Lycopene
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Magnolol ameliorates behavioural impairments and neuropathology in a transgenic model of Alzheimer's disease.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:5920476. Epub 2020 Jul 3. PMID: 32714487
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Magnolol
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

MECHANISMS UNDERLYING THE NEUROTOXICITY INDUCED BY GLYPHOSATE-BASED HERBICIDE IN IMMATURE RAT HIPPOCAMPUS: INVOLVEMENT OF GLUTAMATE EXCITOTOXICITY.Mar 13, 2014

Pubmed Data : Toxicology. 2014 Mar 14. Epub 2014 Mar 14. PMID: 24636977
Article Published Date : Mar 13, 2014
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation , Neurotoxicity, Parkinson's Disease, Parkinsonism
Problem Substances : Glyphosate formulations, Roundup (herbicide)
Adverse Pharmacological Actions : Excitotoxic, Neurotoxic
[+]

Melatonin attenuates sepsis induced brain injury via activation SIRT1 signaling activation.Jun 09, 2015

Pubmed Data : J Pineal Res. 2015 Jun 10. Epub 2015 Jun 10. PMID: 26094939
Article Published Date : Jun 09, 2015
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Brain: Oxidative Stress, Brain Inflammation , Sepsis, Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, SIRT1 Activator, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Significant Treatment Outcome
[+]

Melatonin can be useful as a therapeutic adjuvant for patients under long-term opioid treatment for pain relief.Mar 20, 2016

Pubmed Data : Life Sci. 2016 Mar 21. Epub 2016 Mar 21. PMID: 27012766
Article Published Date : Mar 20, 2016
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Brain Inflammation , Morphine Tolerance/Dependence
Pharmacological Actions : Anti-Inflammatory Agents, Heat Shock Protein Down-Regulation
[+]

Melatonin is effective in reducing maternal LPS-induced neonatal inflammation and related brain injury.Jul 20, 2016

Pubmed Data : J Pineal Res. 2016 Jul 21. Epub 2016 Jul 21. PMID: 27441728
Article Published Date : Jul 20, 2016
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator, Neuroprotective Agents
[+]

Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke.Jan 01, 2011

Pubmed Data : Pediatr Res. 2011 Jan;69(1):51-5. PMID: 20856166
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Brain Inflammation , Demyelinating Diseases, Neonatal Stroke, Stroke: Attenuation/Recovery
Pharmacological Actions : Neuroprotective Agents, Neurorestorative
Additional Keywords : Remyelination
[+]

Modified citrus pectin could effectively inhibit gal3 expression and SNL-induced neuroinflammation and neuropathic pain.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(2):e0148792. Epub 2016 Aug 12. PMID: 26872020
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Modified Citrus Pectin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Neuropathic Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
[+]

Moxibustion can significantly down-regulate hippocampal IL-6 content in fatigue rats.Mar 24, 2019

Pubmed Data : Zhen Ci Yan Jiu. 2019 Mar 25 ;44(3):195-9. PMID: 30945502
Article Published Date : Mar 24, 2019
Study Type : Animal Study
Additional Links
Substances : Moxibustion
Diseases : Brain Inflammation , Fatigue
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
[+]

Mucuna pruriens protects against MPTP intoxicated neuroinflammation in parkinson's disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2017 ;9:421. Epub 2017 Dec 19. PMID: 29311905
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Dopa bean
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Mulberry fruit extract alleviates cognitive impairment by promoting the clearance of amyloid-β and inhibiting neuroinflammation.May 31, 2020

Pubmed Data : Neurochem Res. 2020 Jun 1. Epub 2020 Jun 1. PMID: 32488469
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Mulberry
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

N-acetylcysteine attenuates neuroinflammation associated depressive behaviour induced by chronic unpredictable mild stress.May 16, 2019

Pubmed Data : Behav Brain Res. 2019 May 17 ;364:356-365. Epub 2019 Feb 14. PMID: 30772427
Article Published Date : May 16, 2019
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Nanoparticles derived from metals are capable of inducing brain dysfunction. Jan 01, 2007

Pubmed Data : Prog Brain Res. 2007;162:245-73. PMID: 17645923
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation
Anti Therapeutic Actions : Nanotechnology
Problem Substances : Nanoparticles
[+]

Naringenin decreases α-synuclein expression and neuroinflammation in Parkinson's disease model.Feb 08, 2018

Pubmed Data : Neurotox Res. 2018 Feb 9. Epub 2018 Feb 9. PMID: 29427283
Article Published Date : Feb 08, 2018
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Brain Inflammation, Naringenin, Parkinson's disease
[+]

Naringenin inhibits both inflammatory pain and neurogenic inflammation.Feb 17, 2016

Pubmed Data : Neuropharmacology. 2016 Feb 18. Epub 2016 Feb 18. PMID: 26907804
Article Published Date : Feb 17, 2016
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Brain Inflammation , Neuropathic Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Naringin attenuates Bisphenol-A mediated neurotoxicity in hypertensive rats.Aug 14, 2020

Pubmed Data : Neurotoxicology. 2020 Aug 15 ;81:18-33. Epub 2020 Aug 15. PMID: 32810514
Article Published Date : Aug 14, 2020
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Bisphenol Toxicity, Brain Inflammation , Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Problem Substances : Bisphenol A
[+]

Neuroinflammation is causative for demyelination in MLD mice and that anti-inflammatory treatment might be a novel therapeutic option to improve the CNS function of MLD patients.Jun 30, 2015

Pubmed Data : Mol Ther. 2015 Jul ;23(7):1160-8. Epub 2015 Apr 21. PMID: 25896249
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Inflammation, Leukodystrophy, Leukodystrophy: Metachromatic
Problem Substances : Simvastatin
[+]

Neuromodulatory effect of curcumin on catecholamine systems and inflammatory cytokines in ovariectomized female rats.Oct 23, 2020

Pubmed Data : Clin Exp Pharmacol Physiol. 2020 Oct 24. Epub 2020 Oct 24. PMID: 33098686
Article Published Date : Oct 23, 2020
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuromodulatory effects of green coffee bean extract against brain damage in male albino rats with experimentally induced diabetes. Jun 15, 2020

Pubmed Data : Metab Brain Dis. 2020 Jun 16. Epub 2020 Jun 16. PMID: 32548708
Article Published Date : Jun 15, 2020
Study Type : Animal Study
Additional Links
Substances : Green Coffee Bean
Diseases : Brain Inflammation , Diabetes: Cognitive Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotection by association of palmitoylethanolamide with luteolin in experimental Alzheimer's disease models.Dec 31, 2013

Pubmed Data : CNS Neurol Disord Drug Targets. 2014 ;13(9):1530-41. PMID: 25106636
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Luteolin, Palmitoylethanolamide
Diseases : Brain Inflammation
Pharmacological Actions : Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Neuroprotective effects of Bacopa monnieri in Parkinson's disease model.Dec 12, 2019

Pubmed Data : Metab Brain Dis. 2019 Dec 13. Epub 2019 Dec 13. PMID: 31834548
Article Published Date : Dec 12, 2019
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Nobiletin may serve as a potential approach to alleviate neuroinflammation-related diseases.May 07, 2019

Pubmed Data : J Agric Food Chem. 2019 May 8 ;67(18):5122-5134. Epub 2019 Apr 24. PMID: 30995031
Article Published Date : May 07, 2019
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Oleocanthal and extra-virgin olive oil could provide beneficial effect to slow or halt the progression of Alzheimer's disease.Aug 20, 2019

Pubmed Data : ACS Chem Neurosci. 2019 Aug 21 ;10(8):3543-3554. Epub 2019 Jun 25. PMID: 31244050
Article Published Date : Aug 20, 2019
Study Type : Animal Study
Additional Links
Substances : Oleocanthal
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Oleuropein might be a potential useful therapeutic intervention for PTSD.Sep 06, 2017

Pubmed Data : J Nat Med. 2017 Sep 7. Epub 2017 Sep 7. PMID: 28884427
Article Published Date : Sep 06, 2017
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Brain Inflammation , Post-Traumatic Stress Disorders (PTSD)
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Olive oil contains protective agents that block the expansion of brain core at the expense of penumbral neurons.Oct 31, 2015

Pubmed Data : Nutrition. 2015 Nov-Dec;31(11-12):1430-42. Epub 2015 Jul 2. PMID: 26429666
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Coconut Oil, Grape Seed Extract, Olive Oil
Diseases : Brain Inflammation , Stroke: Attenuation/Recovery , Stroke: Ischemic
Pharmacological Actions : Neuroprotective Agents
[+]

Onion flavonoids have pronounced antioxidant and anti-neuroinflammatory capacities.Dec 31, 2019

Pubmed Data : J Agric Food Chem. 2020 Jan 1. Epub 2020 Jan 1. PMID: 31893634
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Onion
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Oral administration of magnesium-L-threonate reduces neuroinflammation.Nov 08, 2015

Pubmed Data : Cell Mol Immunol. 2015 Nov 9. Epub 2015 Nov 9. PMID: 26549801
Article Published Date : Nov 08, 2015
Study Type : In Vitro Study, Transgenic Animal Study
Additional Links
Substances : Magnesium
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
Additional Keywords : Supplementation
[+]

Overexpression PGC-1α by resveratrol could be a potential therapeutic approach to suppress neuroinflammation.Mar 03, 2017

Pubmed Data : Brain Behav Immun. 2017 Mar 4. Epub 2017 Mar 4. PMID: 28268115
Article Published Date : Mar 03, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Paeoniflorin ameliorates interferon-alpha-induced neuroinflammation and depressive-like behaviours.Jan 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Jan 31 ;8(5):8264-8282. PMID: 28030814
Article Published Date : Jan 30, 2017
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-10 downregulation, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin attenuates chronic cerebral hypoperfusion-induced learning dysfunction and brain damage.May 16, 2006

Pubmed Data : Brain Res. 2006 May 17 ;1089(1):162-70. Epub 2006 May 5. PMID: 16678139
Article Published Date : May 16, 2006
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Brain Inflammation , Brain Ischemia, Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Paeoniflorin attenuates lipopolysaccharide-induced neuronal injury and brain microglial inflammatory response.Jul 31, 2013

Pubmed Data : Biotechnol Lett. 2013 Aug ;35(8):1183-9. Epub 2013 Apr 5. PMID: 23559368
Article Published Date : Jul 31, 2013
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Paeoniflorin use may be a therapeutic strategy in spinal cord injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:9865403. Epub 2018 Dec 2. PMID: 30627586
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Brain Inflammation , Inflammation, Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Panax ginseng and Angelica sinensis treatment attenuates cerebral injury via inhibition of NLRP3 inflammasomes activation and microglial pyroptosis after stroke.May 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2020 May 29 ;76:153251. Epub 2020 May 29. PMID: 32531700
Article Published Date : May 28, 2020
Study Type : Animal Study
Additional Links
Substances : Dong Quai, Ginseng
Diseases : Brain Inflammation , Brain Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Parthenolide ameliorates diabetes-induced behavioural deficit, neurotransmitter imbalance and neuroinflammation in type 2 diabetes rat model.Feb 28, 2017

Pubmed Data : Neuromolecular Med. 2017 Mar ;19(1):101-112. Epub 2016 Aug 23. PMID: 27553015
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Parthenolide
Diseases : Brain Inflammation , Diabetes: Cognitive Dysfunction, Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Parthenolide ameliorates intracerebral hemorrhage-induced brain injury in rats.Sep 08, 2019

Pubmed Data : Phytother Res. 2019 Sep 9. Epub 2019 Sep 9. PMID: 31497910
Article Published Date : Sep 08, 2019
Study Type : Animal Study
Additional Links
Substances : Parthenolide
Diseases : Brain Inflammation , Intracerebral Hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Patchouli alcohol protects against ischemia/reperfusion-induced brain injury.Dec 31, 2017

Pubmed Data : Brain Res. 2018 03 1 ;1682:61-70. Epub 2017 Dec 30. PMID: 29291393
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Patchouli
Diseases : Brain Inflammation , Brain Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Phloretin attenuates behavior deficits and neuroinflammatory response in MPTP induced Parkinson's disease in mice.Jun 24, 2019

Pubmed Data : Life Sci. 2019 Jun 25:116600. Epub 2019 Jun 25. PMID: 31251998
Article Published Date : Jun 24, 2019
Study Type : Animal Study
Additional Links
Substances : Phloretin
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Photobiomodulation can reduce inflammation in the brain, abdominal fat, wounds, lungs, spinal cord.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AIMS Biophys. 2017 ;4(3):337-361. Epub 2017 May 19. PMID: 28748217
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Experimental Lung Inflammation, Inflammation
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Polyphenols derived from lychee seed suppress amyloid-β-induced neuroinflammation.Jul 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Jul 20 ;19(7). Epub 2018 Jul 20. PMID: 30036972
Article Published Date : Jul 19, 2018
Study Type : Animal Study
Additional Links
Substances : Lychee, Polyphenols
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Proanthocyanidins
[+]

Polyphenols from Toona sinensis seeds alleviate neuroinflammation in rats with Parkinson's disease.Aug 31, 2019

Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2019 Sep ;35(9):794-799. PMID: 31750820
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Toona sinensis
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Polyphenols from Toona sinensiss seeds alleviate neuroinflammation induced by 6-hydroxydopamine.Jun 16, 2020

Pubmed Data : Neurochem Res. 2020 Jun 17. Epub 2020 Jun 17. PMID: 32556929
Article Published Date : Jun 16, 2020
Study Type : Animal Study
Additional Links
Substances : Polyphenols, Toona sinensis
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Portulaca oleracea L. prevents lipopolysaccharide-induced passive avoidance learning and memory impairments.Jan 31, 2017

Pubmed Data : Physiol Behav. 2017 Feb 1 ;169:69-73. Epub 2016 Nov 24. PMID: 27889331
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Purslane
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Post-injury curcumin administration may improve patient outcome by reducing acute activation of microglia/macrophages and neuronal apoptosis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2014 ;11:59. Epub 2014 Mar 27. PMID: 24669820
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Brain Inflammation , Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Probiotic formulations could be a promising intervention to improve neuroinflammation-associated disorders such as Alzheimer's disease.Oct 10, 2018

Pubmed Data : J Am Coll Nutr. 2018 Oct 11:1-9. Epub 2018 Oct 11. PMID: 30307792
Article Published Date : Oct 10, 2018
Study Type : Animal Study
Additional Links
Substances : Bifidobacterium Longum , Lactobacillus helveticus
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Prophylactic effect and mechanism of p-coumaric acid against hypoxic cerebral edema in mice.Dec 31, 2018

Pubmed Data : Respir Physiol Neurobiol. 2019 02 ;260:95-104. Epub 2018 Nov 14. PMID: 30447305
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : P-Coumaric Acid
Diseases : Brain: Oxidative Stress, Brain Hypoxia, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Prophylactic Agents
[+]

Protective effect of betulinic acid against intracerebroventricular streptozotocin induced cognitive impairment and neuronal damage.May 31, 2018

Pubmed Data : Pharmacol Rep. 2018 Jun ;70(3):540-548. Epub 2017 Dec 6. PMID: 29674241
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Diseases : Brain Inflammation , Diabetes: Cognitive Dysfunction, Memory Disorders, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Protective effect of exercise training against the progression of Alzheimer's disease in 3xTg-AD mice.Jul 16, 2019

Pubmed Data : Behav Brain Res. 2019 Jul 17 ;374:112105. Epub 2019 Jul 17. PMID: 31325514
Article Published Date : Jul 16, 2019
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Protective effect of Indole-3-carbinol, an NF-κB inhibitor in experimental paradigm of Parkinson's disease.Oct 31, 2020

Pubmed Data : Brain Behav Immun. 2020 Nov ;90:108-137. Epub 2020 Aug 12. PMID: 32800927
Article Published Date : Oct 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of maternal administration of curcumin and hesperidin in the rat offspring following repeated febrile seizure.Jun 21, 2020

Pubmed Data : Int Immunopharmacol. 2020 Jun 22 ;86:106720. Epub 2020 Jun 22. PMID: 32585605
Article Published Date : Jun 21, 2020
Study Type : Animal Study
Additional Links
Substances : Curcumin, Hesperidin
Diseases : Brain Inflammation , Epilepsy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Protective effects of Phyllanthus amarus against lipopolysaccharide-induced neuroinflammation and cognitive impairment.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:632. Epub 2019 Jun 4. PMID: 31231221
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Phyllanthus amarus
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Pu'er tea water extract protects against cognitive impairment in a mouse model of lipopolysaccharide-induced neuroinflammation.Nov 30, 2020

Pubmed Data : Phytomedicine. 2020 Dec ;79:153338. Epub 2020 Sep 19. PMID: 32992081
Article Published Date : Nov 30, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Black Tea
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents
[+]

Puerarin alleviates vincristine-induced neuropathic pain and neuroinflammation.Oct 09, 2020

Pubmed Data : Int Immunopharmacol. 2020 Oct 10 ;89(Pt B):107060. Epub 2020 Oct 10. PMID: 33049496
Article Published Date : Oct 09, 2020
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Brain Inflammation , Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Transforming growth factor beta (TGF-β) upregulation
[+]

Punicalagin inhibits lipopolysaccharide induced memory impairment via anti-inflammatory and anti-amylogenic mechanisms.Jan 25, 2017

Pubmed Data : Neuropharmacology. 2017 Jan 26 ;117:21-32. Epub 2017 Jan 26. PMID: 28132781
Article Published Date : Jan 25, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Punicalagin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Purple sweet potato anthocyanin attenuates high fat-induced neuroinflammation.Jan 16, 2018

Pubmed Data : Mol Med Rep. 2018 Jan 17. Epub 2018 Jan 17. PMID: 29344660
Article Published Date : Jan 16, 2018
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Sweet Potato: Purple
Diseases : Brain Inflammation , High Fat Diet
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Purple sweet potato may be useful for mitigating inflammatory brain diseases by the inhibition of proinflammatory molecule production.Jan 31, 2010

Pubmed Data : Neurochem Int. 2010 Feb ;56(3):424-30. Epub 2009 Nov 24. PMID: 19941923
Article Published Date : Jan 31, 2010
Study Type : Animal Study
Additional Links
Substances : Sweet Potato: Purple
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Quercetin attenuates manganese-induced neuroinflammation by alleviating oxidative stress.Sep 14, 2017

Pubmed Data : Int J Mol Sci. 2017 Sep 15 ;18(9). Epub 2017 Sep 15. PMID: 28914791
Article Published Date : Sep 14, 2017
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Brain Inflammation , Manganese Poisoning
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Rats consuming the berry diets exhibited enhanced motor performance and improved cognition, specifically working memory. Oct 31, 2015

Pubmed Data : Br J Nutr. 2015 Nov ;114(10):1542-9. Epub 2015 Sep 22. PMID: 26392037
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Berries: All
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Oxidative Stress
Pharmacological Actions : Antioxidants, Neurogenesis
[+]

Reishi (Ganoderma lucidum) Protects Dopaminergic Neuron Degeneration Through Inhibition of Microglial Activation.Jul 16, 2009

Pubmed Data : Evid Based Complement Alternat Med. 2009 Jul 16. Epub 2009 Jul 16. PMID: 19617199
Article Published Date : Jul 16, 2009
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Brain: Microglial Activation, Brain Inflammation , Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Resveratrol could be valuable for the prevention of age-associated and disease-provoked inflammation in postmenopausal women.Jul 31, 2016

Pubmed Data : Neurobiol Aging. 2016 Aug ;44:74-84. Epub 2016 Apr 21. PMID: 27318135
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Brain Inflammation , Stroke: Attenuation/Recovery , Stroke: Ischemic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Resveratrol restores the antinociceptive effect of morphine by reversing morphine infusion induced spinal cord neuroinflammation and increase in TNFR1 expression.Jun 11, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Formos Med Assoc. 2015 Jun 12. Epub 2015 Jun 12. PMID: 26078221
Article Published Date : Jun 11, 2015
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Brain Inflammation , Morphine Tolerance/Dependence, Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Disease Reversal, Gene Expression
[+]

Rosmarinic acid mitigates lipopolysaccharide-induced neuroinflammatory responses.Jan 08, 2018

Pubmed Data : Inflammation. 2018 Jan 9. Epub 2018 Jan 9. PMID: 29318480
Article Published Date : Jan 08, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Rosmarinic acid
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type.May 16, 2012

Pubmed Data : Neuroscience. 2012 May 17 ;210:340-52. Epub 2012 Mar 6. PMID: 22441036
Article Published Date : May 16, 2012
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Brain Inflammation , Inflammation, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Selenium deficiency induces inflammation via the iNOS/NF-κB pathway in animals.Nov 19, 2019

Pubmed Data : Biol Trace Elem Res. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31749063
Article Published Date : Nov 19, 2019
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Brain Inflammation , Mineral Deficiencies: Selenium
[+]

Sesamol mitigated Lipopolysaccharide induced amyloidogenesis and memory impairment.Nov 14, 2016

Pubmed Data : Mol Nutr Food Res. 2016 Nov 15. Epub 2016 Nov 15. PMID: 27860258
Article Published Date : Nov 14, 2016
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Short-term cannabidiol treatment results in global functional recovery in ischemic mice.Nov 22, 2016

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2016 Nov 23. Epub 2016 Nov 23. PMID: 27889412
Article Published Date : Nov 22, 2016
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Brain Inflammation , Brain Ischemia
Pharmacological Actions : Neuroplasticity enhancement, Neuroprotective Agents
[+]

Silibinin ameliorated the impairment of learning and memory of LPS-injection rats.Mar 08, 2016

Pubmed Data : Neurochem Res. 2016 Mar 9. Epub 2016 Mar 9. PMID: 26961891
Article Published Date : Mar 08, 2016
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Memory Disorders, Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

Silibinin could be a potential candidate for the therapy of neurodegenerative disorders.Jun 05, 2016

Pubmed Data : Neurosci Lett. 2016 Jun 6 ;629:256-261. Epub 2016 Jun 6. PMID: 27276653
Article Published Date : Jun 05, 2016
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Brain Inflammation , Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-4 downregulation, Interleukin-6 Downregulation
[+]

Silibinin protected dopaminergic neurons in an acute MPTP-induced mouse model of Parkinson's disease.Nov 18, 2015

Pubmed Data : Brain Res. 2015 Nov 19 ;1627:233-42. Epub 2015 Oct 3. PMID: 26434409
Article Published Date : Nov 18, 2015
Study Type : Animal Study
Additional Links
Substances : Silibinin
Diseases : Alzheimer's Disease, Brain Inflammation , Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Studies of interneuron cell-specific knockout of Sema 3F signaling suggest that deficient Sema 3F signaling may lead to neuroinflammation and oxidative stress. Jan 10, 2019

Pubmed Data : Mol Neurobiol. 2019 Jan 11. Epub 2019 Jan 11. PMID: 30635860
Article Published Date : Jan 10, 2019
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders, Brain: Oxidative Stress, Brain Inflammation , Epilepsy
[+]

Sulforaphane ameliorates okadaic acid induced memory impairment in rats by activating the Nrf2/HO-1 antioxidant pathway.Oct 02, 2015

Pubmed Data : Mol Neurobiol. 2015 Oct 3. Epub 2015 Oct 3. PMID: 26433376
Article Published Date : Oct 02, 2015
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Brain Inflammation , Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Supplementation of sesamin alleviates stress-induced behavioral and psychological disorders via reshaping the gut microbiota structure.Nov 12, 2019

Pubmed Data : J Agric Food Chem. 2019 Nov 13 ;67(45):12441-12451. Epub 2019 Nov 1. PMID: 31674783
Article Published Date : Nov 12, 2019
Study Type : Animal Study
Additional Links
Substances : Sesamin
Diseases : Brain Inflammation , Depression, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Gastrointestinal Agents
[+]

T. gondii infection could promote neuroinflammation through cytokine networks and induced hyperalgesia in mice.Jan 31, 2016

Pubmed Data : Inflammation. 2016 Feb ;39(1):405-12. PMID: 26490968
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Hyperalgesia, Toxoplasma gondii Infection
[+]

Tangeretin inhibits neurodegeneration and attenuates inflammatory responses and behavioural deficits in induced Parkinson's disease dementia.Jul 31, 2017

Pubmed Data : Inflammopharmacology. 2017 Aug ;25(4):471-484. Epub 2017 Jun 2. PMID: 28577132
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Tangeretin
Diseases : Brain Inflammation , Dementia, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Interleukin-6 Downregulation
[+]

Tangerine peel possesses potent anti-neuroinflammatory capacity which is attributed to the collective effect of hesperidin, nobiletin, and tangeretin.Aug 31, 2014

Pubmed Data : Food Chem Toxicol. 2014 Sep ;71:176-82. Epub 2014 Jun 20. PMID: 24955543
Article Published Date : Aug 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Citrus Peel , Hesperidin, Nobiletin , Tangeretin
Diseases : Brain Inflammation , Inflammation, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

Tannic acid ameliorates streptozotocin -induced Alzheimer's disease-like impairment of memory.Jan 28, 2020

Pubmed Data : Neurotox Res. 2020 Jan 29. Epub 2020 Jan 29. PMID: 31997154
Article Published Date : Jan 28, 2020
Study Type : Animal Study
Additional Links
Substances : Tannic Acid
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-4 downregulation, Neuroprotective Agents
Problem Substances : Streptozotocin
[+]

Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro.Oct 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2020 Oct 14 ;17(1):302. Epub 2020 Oct 14. PMID: 33054814
Article Published Date : Oct 13, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tanshinone IIA can alleviate sevoflurane-induced neurobehavioral abnormalities and may decrease neuroapoptosis and neuroinflammation.Dec 31, 2016

Pubmed Data : Anesth Analg. 2017 04 ;124(4):1244-1252. PMID: 28319548
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Brain Inflammation , Surgery: Anesthesiology
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Tetrahydrocurcumin mitigates acute hypobaric hypoxia-induced cerebral oedema and inflammation.Jun 22, 2020

Pubmed Data : Phytother Res. 2020 Jun 23. Epub 2020 Jun 23. PMID: 32573860
Article Published Date : Jun 22, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tetrahydrocurcumin
Diseases : Altitude Sickness, Brain Inflammation , Hypoxia: Brain
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

The accumulation of sodium fluoride alters the neurological function which leads to neurodegenerative disorders.Aug 30, 2020

Pubmed Data : Biol Trace Elem Res. 2020 Aug 31. Epub 2020 Aug 31. PMID: 32865723
Article Published Date : Aug 30, 2020
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Fluoride Toxicity
Problem Substances : Sodium Fluoride
[+]

The ameliorative effects of capsidiol isolated from elicited Capsicum annuum on mouse splenocyte immune responses and neuroinflammation.Oct 29, 2020

Pubmed Data : Phytother Res. 2020 Oct 30. Epub 2020 Oct 30. PMID: 33124100
Article Published Date : Oct 29, 2020
Study Type : Animal Study
Additional Links
Substances : Paprika
Diseases : Brain Inflammation , Encephalomyelitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interferon Gamma Reducer, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The antidepressant-like mechanisms of hesperidin are at least partially related to decreased pro-inflammatory cytokine levels.Sep 30, 2016

Pubmed Data : Inflammation. 2016 Oct ;39(5):1681-9. PMID: 27378528
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Brain Inflammation , Depression, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The association of palmitoylethanolamide with luteolin decreases neuroinflammation and stimulates autophagy in Parkinson's disease.Dec 31, 2014

Pubmed Data : CNS Neurol Disord Drug Targets. 2015 ;14(10):1350-65. PMID: 26295827
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Luteolin, Palmitoylethanolamide
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : anti-inflammatory, Autophagy Up-regulation, Neuroprotective Agents
[+]

The combination of gastrodin and rhynchophylline exerts neuroprotective effects by preventing ischaemia-induced inflammasome activation.Oct 10, 2019

Pubmed Data : Life Sci. 2019 Oct 11 ;239:116935. Epub 2019 Oct 11. PMID: 31610203
Article Published Date : Oct 10, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gastrodin
Diseases : Brain Inflammation , Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator, Neuroprotective Agents
[+]

The combination of luteolin and l-theanine improved Alzheimer disease-like symptoms.Nov 30, 2018

Pubmed Data : Nutr Res. 2018 Dec ;60:116-131. Epub 2018 Oct 2. PMID: 30527255
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Luteolin, Theanine
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

The data from this study supports the view that inhibition of microglial activation may improve schizophrenia symptoms.Apr 30, 2015

Pubmed Data : Schizophr Res. 2015 May ;164(1-3):155-63. Epub 2015 Feb 10. PMID: 25680767
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Brain Inflammation , Schizophrenia
Pharmacological Actions : Anti-Inflammatory Agents, Antipsychotic Agents, Neuroprotective Agents
Additional Keywords : Clozapine, Natural Substances Versus Drugs
[+]

The effects of voluntary wheel running on neuroinflammatory status.Dec 31, 2016

Pubmed Data : Mol Cell Neurosci. 2017 03 ;79:93-102. Epub 2017 Jan 11. PMID: 28088610
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The flavonoid baicalin found in Chinese skullcap protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.Mar 01, 2007

Pubmed Data : Neuropharmacology. 2007 Mar;52(3):1024-33. Epub 2007 Jan 3. PMID: 17204294
Article Published Date : Mar 01, 2007
Study Type : Animal Study
Additional Links
Substances : Catechols, Chinese Skullcap , Flavonoids
Diseases : Brain Inflammation , Heat Stroke
[+]

The present study points out the protective effects of A. indica extract on pyramidal neurons in experimental cerebral malaria induced by P. berghei-infection in mice.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Malar J. 2013 ;12:298. Epub 2013 Aug 29. PMID: 23984986
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Neem
Diseases : Brain Inflammation , Malaria
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

The probiotic L. helveticus strain NS8 is beneficial for the treatment of cognitive decline and anxiety-like behavior in HA rats.Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci China Life Sci. 2014 Mar ;57(3):327-35. Epub 2014 Feb 19. PMID: 24554471
Article Published Date : Feb 28, 2014
Study Type : Animal Study
Additional Links
Substances : Lactobacillus probiotics
Diseases : Anxiety Disorders, Brain Inflammation , Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

The results achieved in this study support the idea that CBD has a cerebroprotective effect.Sep 04, 2017

Pubmed Data : Brain Inj. 2017 Sep 5:1-12. Epub 2017 Sep 5. PMID: 28872345
Article Published Date : Sep 04, 2017
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Brain Inflammation , Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents,