Chronic Kidney Disease (CKD)

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69 Substances Researched for Chronic Kidney Disease (CKD)
NameACCKFocus
Vitamin D871Locked
Vitamin C440Locked
Curcumin625Locked
Fiber120Locked
Omega-3 Fatty Acids220Locked
Sodium Bicarbonate220Locked
Turmeric220Locked
Ginsenosides313Locked
Magnesium312Locked
Propolis: Brazillian212Locked
Okra211Locked
Activated Charcoal 110Locked
Beta-glucan110Locked
Boswellia110Locked
Calcium110Locked
Frankincense110Locked
Fruit: All110Locked
Nigella sativa (aka Black Seed)110Locked
Oats110Locked
Phytate110Locked
Pomegranate110Locked
Resistant Starch110Locked
S-Adenosylmethionine (SAMe)110Locked
Stevia110Locked
Vegetables: All 110Locked
Vitamin B-6110Locked
Vitamin C: Intravenous 110Locked
Fucoidan36Locked
Allicin24Locked
Tanshinone IIA24Locked
Resveratrol33Locked
Amygdalin12Locked
Asiatic Acid12Locked
Astragaloside12Locked
Bee Venom12Locked
Chaga Mushroom (Inonotus obliquus)12Locked
Cordyceps Militaris12Locked
Formononetin12Locked
Fucoxanthin 12Locked
Kefir12Locked
L-Carnitine12Locked
Lactobacillus paracasei12Locked
Lactobacillus plantarum12Locked
Melatonin22Locked
Naringenin 12Locked
Paeoniflorin12Locked
Poria cocos12Locked
Probiotics12Locked
Rhubarb12Locked
Tangeretin 12Locked
Vitamin K12Locked
Vitamin K212Locked
Xanthones12Locked
Zinc12Locked
Astaxanthin11Locked
Berberine11Locked
Carnosine11Locked
Coenzyme Q1011Locked
Cranberry11Locked
Cruciferous Vegetables11Locked
EPA (Eicosapentaenoic Acid)11Locked
Emodin11Locked
Lotus 11Locked
Niacin11Locked
Oleuropein11Locked
Quercetin11Locked
Reishi Mushroom11Locked
Silymarin11Locked
Sulforaphane11Locked
12 Problem Substances Researched for Chronic Kidney Disease (CKD)
NameACCKFocus
Proton-Pump Inhibitors440Locked
Bisphenol A 431Locked
Statin Drugs110Locked
Fluoride23Locked
Dichloro-diphenyl-trichloroethane (DDT) 12Locked
Gadolinium 12Locked
Lead12Locked
Monosodium Glutamate (MSG)12Locked
Glyphosate11Locked
Paraquat11Locked
Sodium Fluoride11Locked
Sugar Sweetened Beverages11Locked
9 Therapeutic Actions Researched for Chronic Kidney Disease (CKD)
NameACCKFocus
Dietary Modification: Vegetarian422Locked
Dietary Modification: Low Carbohydrate/Ketogenic110Locked
Dietary Modification: Mediterranean Diet110Locked
Dietary Modification: Vegan Diet110Locked
Exercise110Locked
Exercise: Resistance Training110Locked
Pilates110Locked
Therapeutic Breathing110Locked
Ozone Therapy 12Locked
1 Problematic Actions Researched for Chronic Kidney Disease (CKD)
NameACCKFocus
Western Diet11Locked

View the Evidence:
126 Abstracts with Chronic Kidney Disease (CKD) Research

[+]

This study summarizes the potential beneficial effects of dietary fiber in the CKD population demonstrating a reduction in serum urea and creatinine.Jun 30, 2015

Pubmed Data : Eur J Clin Nutr. 2015 Jul ;69(7):761-8. Epub 2014 Nov 12. PMID: 25387901
Article Published Date : Jun 30, 2015
Study Type : Meta Analysis, Review
Additional Links
Substances : Fiber
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Renoprotective
Additional Keywords : Risk Reduction
[+]

25OHD deficiency is a risk factor for secondary hyperparathyroidism and decreased serum 1,25(OH)2D in children with CKD.Aug 25, 2015

Pubmed Data : Pediatr Nephrol. 2015 Aug 26. Epub 2015 Aug 26. PMID: 26307635
Article Published Date : Aug 25, 2015
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

A diet rich in vegetables and fruit may reduce the risk for kidney disease.Apr 26, 2019

Pubmed Data : Am J Kidney Dis. 2019 Apr 27. Epub 2019 Apr 27. PMID: 31040089
Article Published Date : Apr 26, 2019
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Chronic Kidney Disease (CKD)
Additional Keywords : Risk Reduction
[+]

A manihot is a promising therapy for patients with primary kidney disease.Jun 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Kidney Dis. 2014 Jul ;64(1):57-65. Epub 2014 Mar 14. PMID: 24631042
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : Okra
Diseases : Chronic Kidney Disease (CKD), Proteinuria
Pharmacological Actions : Renoprotective
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

Pubmed Data : J Altern Complement Med. 2017 Aug ;23(8):632-638. Epub 2017 Apr 4. PMID: 28375641
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Chronic Kidney Disease (CKD), Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

A vitamin D deficiency at baseline is significantly correlated with poorer clinical outcomes and more sever renal pathological features.Nov 01, 2016

Pubmed Data : BMC Nephrol. 2016 Nov 2 ;17(1):164. Epub 2016 Aug 2. PMID: 27806690
Article Published Date : Nov 01, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Acute phase proteins and vitamin D seasonal variation in end-stage renal disease patients.Mar 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2020 Mar 16 ;9(3). Epub 2020 Mar 16. PMID: 32188088
Article Published Date : Mar 15, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Renoprotective
[+]

Adequate consumption of phytate can prevent abdominal aortic calcification in patients with chronic kidney disease.Dec 31, 2015

Pubmed Data : J Ren Nutr. 2016 07 ;26(4):226-36. Epub 2016 Mar 12. PMID: 26975775
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Phytate
Diseases : Aortic Calcification, Chronic Kidney Disease (CKD)
[+]

Adherence to the Mediterranean diet has favourable effects on the prevention of kidney dysfunction.Aug 10, 2016

Pubmed Data : Hypertens Res. 2016 Aug 11. Epub 2016 Aug 11. PMID: 27511053
Article Published Date : Aug 10, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Additional Keywords : Risk Reduction
[+]

Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Kidney J. 2018 Aug ;11(4):532-539. Epub 2018 Feb 6. PMID: 30094018
Article Published Date : Jul 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Antihypertensive Agents
[+]

Ascorbic acid might be a promising agent in chronic kidney disease for improving outcome by decreasing oxidative stress and ADMA levels.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Kidney J. 2018 Aug ;11(4):530-531. Epub 2018 Jun 26. PMID: 30094017
Article Published Date : Jul 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Antioxidants
[+]

Beneficial effects of 6-month supplementation with omega-3 acids on selected inflammatory markers in patients with chronic kidney disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2017 ;2017:1680985. Epub 2017 Nov 19. PMID: 29349065
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Breathing training program improves quality of life in patients with predialysis chronic kidney disease.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Palliat Care. 2020 Jul-Sep;26(3):271-275. Epub 2020 Aug 29. PMID: 33311865
Article Published Date : Jun 30, 2020
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Quality of Life: Poor
Therapeutic Actions : Therapeutic Breathing
[+]

Combined sodium bicarbonate and ascorbic acid could prevent contrast-induced nephropathy following catheterization in CKD patients.Jan 24, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Circ J. 2017 Jan 25 ;81(2):235-240. Epub 2016 Dec 22. PMID: 28003574
Article Published Date : Jan 24, 2017
Study Type : Human Study
Additional Links
Substances : Sodium Bicarbonate, Vitamin C
Diseases : Chronic Kidney Disease (CKD), Nephropathy
Pharmacological Actions : Renoprotective
Additional Keywords : Risk Reduction
[+]

Curcumin and Boswellia serrata are safe and tolerable and helped to improvethe levels of an inflammatory cytokine (IL-6).Dec 31, 2012

Pubmed Data : J Complement Integr Med. 2013 ;10(1):1-10. Epub 2013 Jul 1. PMID: 23828329
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Boswellia, Turmeric
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
Additional Keywords : Substance Combination
[+]

Dietary beta-glucans could decrease the levels of the proteolytic uremic toxins p-cresyl sulphate.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(1):e0169635. Epub 2017 Jan 20. PMID: 28107445
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Beta-glucan
Diseases : Chronic Kidney Disease (CKD), Endothelial Dysfunction
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Microbiota
[+]

Effect of Omega-3 supplements on quality of life among children on dialysis.Oct 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicine (Baltimore). 2020 Oct 2 ;99(40):e22240. PMID: 33019398
Article Published Date : Oct 01, 2020
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Chronic Kidney Disease (CKD), Dialysis: Renal
[+]

Effects of Brazilian green propolis on proteinuria and renal function in patients with chronic kidney disease.Apr 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Nephrol. 2019 Apr 25 ;20(1):140. Epub 2019 Apr 25. PMID: 31023272
Article Published Date : Apr 24, 2019
Study Type : Human Study
Additional Links
Substances : Propolis: Brazillian
Diseases : Chronic Kidney Disease (CKD), Proteinuria
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective
[+]

Ginsenoside Rb1 treatment was effective in reducing the extent of oxidative stress and inflammation in chronic kidney disease patients.Jan 31, 2017

Pubmed Data : Inflammopharmacology. 2017 Feb ;25(1):33-40. Epub 2016 Nov 17. PMID: 27853891
Article Published Date : Jan 31, 2017
Study Type : Human Study
Additional Links
Substances : Ginsenosides
Diseases : Chronic Kidney Disease (CKD), Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

High homocysteine, low vitamin B-6, and increased oxidative stress are independently associated with the risk of chronic kidney disease.Jan 31, 2016

Pubmed Data : Nutrition. 2016 Feb ;32(2):236-41. Epub 2015 Sep 25. PMID: 26526964
Article Published Date : Jan 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin B-6
Diseases : Chronic Kidney Disease (CKD), High Homocysteine, Oxidative Stress, Vitamin B6 Depletion
Pharmacological Actions : Antioxidants
Additional Keywords : Risk Factors
[+]

Higher serum magnesium level may be associated with better endothelial function in end stage renal disease patients on hemodialysis.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Yonsei Med J. 2016 Nov ;57(6):1446-53. PMID: 27593873
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Chronic Kidney Disease (CKD), Endothelial Dysfunction, Hemodialysis, Magnesium Deficiency
[+]

Hypovitaminosis D is associated with subclinical peripheral arterial disease, independently of other cardiovascular risk factors.Sep 30, 2016

Pubmed Data : Arch Med Sci. 2016 Oct 1 ;12(5):1015-1022. Epub 2016 Aug 24. PMID: 27695492
Article Published Date : Sep 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Cardiovascular Diseases, Chronic Kidney Disease (CKD), Peripheral Arterial Disease, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Insufficient renal function may lead to bisphenol A accumulation in patients with chronic kidney disease.Sep 17, 2019

Pubmed Data : Ecotoxicol Environ Saf. 2019 Sep 18 ;185:109684. Epub 2019 Sep 18. PMID: 31541948
Article Published Date : Sep 17, 2019
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Chronic Kidney Disease (CKD)
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
[+]

Intake of oats may have a beneficial effect on serum albumin and serum potassium in patients with chronic kidney disease.Dec 01, 2016

Pubmed Data : Clin Nutr. 2016 Dec 2. Epub 2016 Dec 2. PMID: 28003041
Article Published Date : Dec 01, 2016
Study Type : Human Study
Additional Links
Substances : Oats
Diseases : Chronic Kidney Disease (CKD)
[+]

Intravenous ascorbic acid could be a new successful adjuvant in reducing ferritin and erythropoietin resistance in chronic kidney disease patients.Jun 30, 2017

Pubmed Data : J Assoc Physicians India. 2017 Jul ;65(7):32-36. PMID: 28792166
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin C: Intravenous
Diseases : Chronic Kidney Disease (CKD)
[+]

Kidney disease is associated with in-hospital death of patients with COVID-19.Mar 19, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kidney Int. 2020 Mar 20. Epub 2020 Mar 20. PMID: 32247631
Article Published Date : Mar 19, 2020
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Coronavirus Disease
Additional Keywords : Increased Risk, Mortality
[+]

Low serum magnesium were independently associated with all-cause death in patients with prevalent chronic kidney disease.Oct 24, 2017

Pubmed Data : Nephrol Dial Transplant. 2017 Oct 25. Epub 2017 Oct 25. PMID: 29077944
Article Published Date : Oct 24, 2017
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Chronic Kidney Disease (CKD), Magnesium Deficiency
Additional Keywords : Risk Factors
[+]

Lower serum calcium is independently associated with chronic kidney disease progression.Mar 25, 2018

Pubmed Data : Sci Rep. 2018 Mar 26 ;8(1):5148. Epub 2018 Mar 26. PMID: 29581540
Article Published Date : Mar 25, 2018
Study Type : Human Study
Additional Links
Substances : Calcium, Vitamin D
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
[+]

Moderate protein restriction in a vegan-vegetarian supplemented diet is confirmed as a safe option in the management of pregnant CKD patients.Sep 19, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Nephrol. 2016 Sep 20 ;17(1):132. Epub 2016 Sep 20. PMID: 27649693
Article Published Date : Sep 19, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Vegan Diet, Dietary Modification: Vegetarian
Additional Keywords : Chronic Kidney Disease (CKD), Pregnancy, pregnant women, Vegan, vegetarian, women's health
[+]

Multiple heavy metals and agrochemicals such as glyphosate and their residues acting synergistically may play a role in the pathogenesis of SAN.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Nephrol. 2015 ;16:103. Epub 2015 Jul 11. PMID: 26162605
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Glyphosate Toxicity, Heavy Metal Toxicity
Additional Keywords : Sri Lankan Agricultural Nephropathy
[+]

N. sativa oil supplementation along with alpha-keto analogue is efficacious and safe in delaying the progression of disease patients with CKD Stages 3 and 4.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Kidney Dis Transpl. 2020 Jan-Feb;31(1):21-31. PMID: 32129194
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Renoprotective
Additional Keywords : Risk Reduction
[+]

Nondiabetic patients with stage 3-4 CKD and vitamin D deficiency, vitamin D supplementation may improve vascular function.Sep 30, 2017

Pubmed Data : J Am Soc Nephrol. 2017 Oct ;28(10):3100-3108. Epub 2017 Jun 30. PMID: 28667080
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Interleukin-6 Downregulation, Vasoprotective
[+]

Oral activated charcoal effectively delays the onset of hyperphosphatemia in patients with chronic kidney disease.Dec 25, 2018

Pubmed Data : J Nephrol. 2018 Dec 26. Epub 2018 Dec 26. PMID: 30588573
Article Published Date : Dec 25, 2018
Study Type : Human Study
Additional Links
Substances : Activated Charcoal
Diseases : Chronic Kidney Disease (CKD), Vascular Calcification
Pharmacological Actions : Renoprotective
[+]

Oral cholecalciferol administration increased 25-hydroxyvitamin D and mildly reduced PTH serum levels.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nephrol Renovasc Dis. 2015;8:151-157. Epub 2015 Nov 19. PMID: 26640388
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
Additional Keywords : Supplementation
[+]

Patients with type 2 diabetes and high levels of serum BPA exhibited about a sevenfold increased risk of developing CKD compared to patients with low levels of serum BPA.Aug 31, 2015

Pubmed Data : Acta Diabetol. 2015 Sep 1. Epub 2015 Sep 1. PMID: 26321107
Article Published Date : Aug 31, 2015
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Diabetes Mellitus: Type 2, Diabetic Nephropathy
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
[+]

Pilates exercises can be valuable for improvement of chronic kidney disease patients' quality of life.Jan 31, 2019

Pubmed Data : Complement Ther Clin Pract. 2019 Feb ;34:35-40. Epub 2018 Nov 1. PMID: 30712743
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Quality of Life: Poor
Therapeutic Actions : Pilates
[+]

Pomegranate extract supplementation may reduce BP and increase the antioxidant activity in HD patients.Mar 30, 2015

Pubmed Data : J Med Food. 2015 Mar 31. Epub 2015 Mar 31. PMID: 25826143
Article Published Date : Mar 30, 2015
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Chronic Kidney Disease (CKD), Hemodialysis
Pharmacological Actions : Antihypertensive Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Prebiotic-resistant starch supplementation seems to be a promising nutritional strategy to improve inflammation, oxidative stress and to reduce indoxyl sulfate plasma levels in chronic kidney disease patients on hemodialysis.Dec 13, 2018

Pubmed Data : Food Funct. 2018 Dec 13 ;9(12):6508-6516. PMID: 30468238
Article Published Date : Dec 13, 2018
Study Type : Human Study
Additional Links
Substances : Resistant Starch
Diseases : C-Reactive Protein, Chronic Kidney Disease (CKD), Hemodialysis, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Interleukin-6 Downregulation
[+]

Proton pump inhibitors use and risk of chronic kidney disease in diabetic patients.Nov 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetes Res Clin Pract. 2018 Nov 27 ;147:67-75. Epub 2018 Nov 27. PMID: 30500543
Article Published Date : Nov 26, 2018
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitors use is associated with a higher risk of incident chronic kidney disease.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(10):e0204231. Epub 2018 Oct 17. PMID: 30332411
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Kidney Damage: Drug-Induced
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Proton pump inhibitors use was associated with progression to major adverse renal events in patients with chronic kidney disease.Jun 27, 2019

Pubmed Data : QJM. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31251364
Article Published Date : Jun 27, 2019
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Problem Substances : Proton-Pump Inhibitors
[+]

Regular ingestion of turmeric reduces plasma malondialdehyde and increases red blood cell catalase activity and plasma albumin levels in hemodialysis patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Hemodial Int. 2015 Jan ;19(1):124-31. Epub 2014 Aug 16. PMID: 25131305
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Chronic Kidney Disease (CKD), Hemodialysis, Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Malondialdehyde Down-regulation
Additional Keywords : Significant Treatment Outcome
[+]

Resistance exercise performed in the intradialytic phase is an effective therapeutic strategy for chronic kidney disease patients.Mar 07, 2021

Pubmed Data : Hemodial Int. 2021 Mar 8. Epub 2021 Mar 8. PMID: 33682262
Article Published Date : Mar 07, 2021
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Hemodialysis
Therapeutic Actions : Exercise: Resistance Training
Pharmacological Actions : Renoprotective
[+]

S-adenosylmethionine has nephroprotective properties.Nov 30, 2017

Pubmed Data : Georgian Med News. 2017 Dec(273):31-36. PMID: 29328026
Article Published Date : Nov 30, 2017
Study Type : Human Study
Additional Links
Substances : S-Adenosylmethionine (SAMe)
Diseases : Chronic Kidney Disease (CKD), Liver Steatosis, Obesity
Pharmacological Actions : Antioxidants, Renoprotective
[+]

Serially assessed bisphenol A and phthalate exposure and association with kidney function in children with chronic kidney disease.Sep 30, 2020

Pubmed Data : PLoS Med. 2020 Oct ;17(10):e1003384. Epub 2020 Oct 14. PMID: 33052911
Article Published Date : Sep 30, 2020
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Chronic Kidney Disease (CKD), Inflammation, Oxidative Stress
Problem Substances : Bisphenol A
[+]

Six months yoga program is safe and effective as an adjuvant therapy in improving renal functions and QOL of CKD patients.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Yoga. 2017 Jan-Apr;10(1):3-8. PMID: 28149061
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Quality of Life: Poor
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Antihypertensive Agents, Chronic Kidney Disease (CKD), Quality of Life: Poor, yoga
[+]

Sodium bicarbonate supplementation is associated with a decrease in electronegative LDL in chronic kidney disease patients.Sep 30, 2017

Pubmed Data : Cardiorenal Med. 2017 Oct ;7(4):334-341. Epub 2017 Aug 17. PMID: 29118772
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Substances : Sodium Bicarbonate
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Hypolipidemic, Renoprotective
[+]

Stevia has the potential for a significant improvement of some biochemical parameters in chronic kidney disease patients.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Contemp Clin Trials Commun. 2018 Dec ;12:17-25. Epub 2018 Aug 21. PMID: 30211340
Article Published Date : Nov 30, 2018
Study Type : Human Study
Additional Links
Substances : Stevia
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Hypoglycemic Agents, Renoprotective, Uricosuric Agents
[+]

Taking proton pump inhibitors is associated with a small excess of cause specific mortality.Jan 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ. 2019 05 29 ;365:l1580. Epub 2019 May 29. PMID: 31147311
Article Published Date : Jan 28, 2019
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Chronic Kidney Disease (CKD), Gastrointestinal Cancer
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

The effect of dietary nitrate on exercise capacity in chronic kidney disease.Oct 16, 2020

Pubmed Data : Nitric Oxide. 2020 Oct 17. Epub 2020 Oct 17. PMID: 33080411
Article Published Date : Oct 16, 2020
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Exercise
[+]

The ketogenic diet seems nutritionally safe and could defer dialysis initiation in some patients with chronic kidney disease.Jan 27, 2016

Pubmed Data : J Am Soc Nephrol. 2016 Jan 28. Epub 2016 Jan 28. PMID: 26823552
Article Published Date : Jan 27, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Dietary Modification: Vegetarian
Pharmacological Actions : Renoprotective
Additional Keywords : Risk Reduction
[+]

This study demonstrated that CKD patients had increased plasma TMAO levels due to contributions from both impaired renal functions and dysbiosis of the gut microbiota.Jan 03, 2017

Pubmed Data : Sci Rep. 2017 05 3 ;7(1):1445. Epub 2017 May 3. PMID: 28469156
Article Published Date : Jan 03, 2017
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
[+]

This study demonstrated the association between vitamin D deficiency and depression in CKD patients.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(2):e0171009. Epub 2017 Feb 13. PMID: 28192445
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Depression, Vitamin D Deficiency
[+]

This study describes high prevalence of vitamin C insufficiency among pediatric chronic kidney disease patients.Jul 18, 2020

Pubmed Data : Pediatr Nephrol. 2020 Jul 19. Epub 2020 Jul 19. PMID: 32683655
Article Published Date : Jul 18, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Chronic Kidney Disease (CKD), Vitamin C Deficiency
[+]

This study found that patients with chronic kidney disease and taking statins had lower 25-OH-D3 levels. Feb 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nefrologia. 2015 Mar-Apr;35(2):150-6. Epub 2015 Jun 23. PMID: 26300508
Article Published Date : Feb 28, 2015
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Drug-Induced Nutrient Depletion: Statin Drugs, Vitamin D Deficiency
Problem Substances : Statin Drugs
[+]

Three months treatment with curcumin in chronic kidney disease patients undergoing hemodialysis resulted in decreased markers of inflammation.Mar 12, 2020

Pubmed Data : Clin Nutr. 2020 Mar 13. Epub 2020 Mar 13. PMID: 32204978
Article Published Date : Mar 12, 2020
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Usefulness of extra virgin olive oil minor polar compounds in the management of chronic kidney disease patients.Feb 09, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Feb 10 ;13(2). Epub 2021 Feb 10. PMID: 33578682
Article Published Date : Feb 09, 2021
Study Type : Human Study
Additional Links
Substances : Olive, Polyphenols
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Vitamin D and folic acid are universally deficient in the diets of patients with chronic kidney disease.May 31, 2016

Pubmed Data : Transplant Proc. 2016 Jun ;48(5):1427-30. PMID: 27496421
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Folic Acid/Folate Deficiency, Vitamin D Deficiency
[+]

Alleviating chronic kidney disease progression through modulating the critical genus of gut microbiota in a cisplatin-induced Lanyu pig model.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Food Drug Anal. 2020 Jan ;28(1):103-114. Epub 2019 Oct 17. PMID: 31883598
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus paracasei, Lactobacillus plantarum, Probiotics
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Chemoprotective Agents, Renoprotective
[+]

Allicin showed an antihypertensive, nephroprotective, cardioprotective, and antioxidant effects.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:3850402. Epub 2016 Nov 21. PMID: 27990229
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Chronic Kidney Disease (CKD), Hypertension, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Cardioprotective, Renoprotective
[+]

Amygdalin is a potent antifibrotic agent that may have therapeutic potential for patients with fibrotic kidney diseases.Apr 30, 2013

Pubmed Data : Mol Med Rep. 2013 May ;7(5):1453-7. Epub 2013 Mar 22. PMID: 23525378
Article Published Date : Apr 30, 2013
Study Type : Animal Study
Additional Links
Substances : Amygdalin
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Antiproliferative , Renoprotective
[+]

Asiatic acid and naringenin may represent as a novel and effective therapy for chronic kidney disease associated with fibrosis.Nov 09, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Nov 10 ;6(35):36984-97. PMID: 26474462
Article Published Date : Nov 09, 2015
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid, Naringenin
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Astragaloside IV improves renal function and fibrosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2018 ;12:2431-2442. Epub 2018 Aug 6. PMID: 30122901
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Chronic Kidney Disease (CKD), Diabetic Complications, Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Bee venom may be a useful therapeutic agent for the prevention of fibrosis that characterizes progression of chronic kidney disease.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2015 Jun ;7(6):1917-28. Epub 2015 May 29. PMID: 26035488
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Brazilian red propolis treatment attenuated hypertension and structural renal damage in a renal ablation model.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(1):e0116535. Epub 2015 Jan 21. PMID: 25607548
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Propolis: Brazillian
Diseases : Chronic Kidney Disease (CKD), Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Antioxidants, Renoprotective
[+]

Chronic monosodium glutamate (MSG) intake causes kidney dysfunction and renal oxidative stress in the animal model.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(12):e116233. Epub 2014 Dec 31. PMID: 25551610
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Kidney Damage, Kidney Failure: Chronic
Problem Substances : Monosodium Glutamate (MSG)
[+]

Cordyceps militaris protected against chronic kidney disease progression.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:7850863. Epub 2019 Mar 31. PMID: 31049139
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcuma aromatica oil administration ameliorates renal fibrosis symptoms by inhibiting metabolic pathways, lipid metabolism, glycolysis and methylamine metabolism.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(9):e108678. Epub 2014 Sep 29. PMID: 25265289
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective
[+]

Curcumin exhibits salutary effects against adenine-induced chronic kidney disease in rats by reducing inflammation and oxidative stress.May 30, 2017

Pubmed Data : Basic Clin Pharmacol Toxicol. 2017 May 31. Epub 2017 May 31. PMID: 28561324
Article Published Date : May 30, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation
[+]

Diesel exhaust particles worsen renal oxidative stress, inflammation and DNA damage in mice with adenine-induced chronic renal failure.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2016 ;38(5):1703-13. Epub 2016 May 3. PMID: 27160713
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Diesel Exhaust Particle Toxicity , DNA damage, Oxidative Stress
[+]

Effect of water fluoridation on the development of medial vascular calcification in uremic rats.Apr 05, 2014

Pubmed Data : Toxicology. 2014 Apr 6 ;318:40-50. Epub 2014 Feb 18. PMID: 24561004
Article Published Date : Apr 05, 2014
Study Type : Animal Study
Additional Links
Diseases : Arterial Calcification, Atheroma, Atherosclerosis, Chronic Kidney Disease (CKD), Ectopic Calcification, Fluoride Toxicity
Problem Substances : Fluoride
Adverse Pharmacological Actions : Cardiotoxic
[+]

Formononetin ameliorates muscle atrophy.Jan 05, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2021 Jan 6. Epub 2021 Jan 6. PMID: 33405354
Article Published Date : Jan 05, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Formononetin
Diseases : Chronic Kidney Disease (CKD), Muscle Atrophy
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoidan improves bioactivity and vasculogenic potential of mesenchymal stem cells in murine hind limb ischemia associated with chronic kidney disease.Dec 31, 2015

Pubmed Data : J Mol Cell Cardiol. 2016 08 ;97:169-79. Epub 2016 May 20. PMID: 27216370
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Chronic Kidney Disease (CKD), Ischemia
Additional Keywords : Mesenchymal Stem Cells
[+]

Gadolinium tissue deposition in the periodontal ligament of mice with reduced renal function.Jan 31, 2019

Pubmed Data : Toxicol Lett. 2019 Feb ;301:157-167. Epub 2018 Nov 23. PMID: 30476537
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Gadolinium Toxicity
Problem Substances : Gadolinium
[+]

Ginsenoside protects against AKI via activation of HIF 1α and VEGF A in the kidney brain axis.Jan 14, 2020

Pubmed Data : Int J Mol Med. 2020 Jan 15. Epub 2020 Jan 15. PMID: 31985021
Article Published Date : Jan 14, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Chronic Kidney Disease (CKD), Kidney Damage
Pharmacological Actions : Antioxidants, Renoprotective
[+]

Ginsenoside Rb1 ameliorates chronic kidney disease-associated vascular calcification by inhibiting the Wnt/β-catenin pathway.Aug 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Aug 19. Epub 2019 Aug 19. PMID: 31423730
Article Published Date : Aug 18, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Vascular Calcification
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
[+]

Low-molecular-weight polysaccharides of Inonotus obliquus may be advantageous to control the progression of CKD.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(9). Epub 2016 Sep 13. PMID: 27649140
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Chronic Kidney Disease (CKD), Diabetic Nephropathy
Pharmacological Actions : NF-kappaB Inhibitor, Renoprotective
[+]

Oligo-fucoidan prevents renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway.Jan 17, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 01 18 ;7:40183. Epub 2017 Jan 18. PMID: 28098144
Article Published Date : Jan 17, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Chronic Kidney Disease (CKD), Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Oligo-fucoidan, fucoxanthin, and L-carnitine have a combined protective effect on the kidneys.Nov 01, 2020

Pubmed Data : Eur J Pharmacol. 2020 Nov 2:173708. Epub 2020 Nov 2. PMID: 33152336
Article Published Date : Nov 01, 2020
Study Type : Animal Study
Additional Links
Substances : Fucoidan, Fucoxanthin , L-Carnitine
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Renoprotective
[+]

Paeoniflorin inhibits mesangial cell proliferation and inflammatory response in rats with mesangial proliferative glomerulonephritis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:978. Epub 2019 Sep 9. PMID: 31551783
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative
[+]

Rescue therapy with tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease.Jan 17, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 11 18 ;6:36698. Epub 2016 Nov 18. PMID: 27857162
Article Published Date : Jan 17, 2016
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : anti-inflammatory, Renoprotective
[+]

Rice bran modulates renal disease risk factors in animals submitted to high sugar-fat diet.Jan 14, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Bras Nefrol. 2021 Jan 15. Epub 2021 Jan 15. PMID: 33475676
Article Published Date : Jan 14, 2021
Study Type : Animal Study
Additional Links
Substances : Rice Bran
Diseases : Chronic Kidney Disease (CKD), High Fat Diet, High Sugar Diet
Pharmacological Actions : Renoprotective
[+]

Sperm epimutation biomarkers of obesity and pathologies following DDT induced epigenetic transgenerational inheritance of disease.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Epigenet. 2019 Apr ;5(2):dvz008. Epub 2019 May 27. PMID: 31186947
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Obesity, Pesticide Toxicity
Additional Keywords : Increased Risk, Transgenerational Epigenetic Modification
Problem Substances : Dichloro-diphenyl-trichloroethane (DDT)
[+]

Tangeretin effectively improved renal function and reduced the cognitive and memory impairments in chronic kidney disease.Sep 03, 2017

Pubmed Data : Inflammopharmacology. 2017 Sep 4. Epub 2017 Sep 4. PMID: 28871498
Article Published Date : Sep 03, 2017
Study Type : Animal Study
Additional Links
Substances : Tangeretin
Diseases : Chronic Kidney Disease (CKD), Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tanshinone IIA might be a novel therapy for preventing progression of chronic kidney disease after acute kidney injury.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:867140. Epub 2015 Dec 29. PMID: 26885500
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chronic Kidney Disease (CKD), Kidney Damage
Pharmacological Actions : Renoprotective
[+]

The beneficial effects of allicin in chronic kidney disease are comparable to losartan.Sep 15, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Sep 16 ;18(9). Epub 2017 Sep 16. PMID: 28926934
Article Published Date : Sep 15, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Renoprotective
Additional Keywords : Natural Substances Versus Drugs
[+]

The results of this study suggest that kefir peptides ameliorate salt-induced renal damage.Aug 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Aug 26 ;9(9). Epub 2020 Aug 26. PMID: 32858955
Article Published Date : Aug 25, 2020
Study Type : Animal Study
Additional Links
Substances : Kefir
Diseases : Chronic Kidney Disease (CKD), Kidney Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

These results indicated that ozone therapy might reduce sterile renal inflammation and slow down chronic kidney disease progression.Jan 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Feb ;43:203-209. Epub 2016 Dec 27. PMID: 28038382
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Inflammation
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective
[+]

Treatment with rhubarb extracts may represent as an effective therapy for chronic kidney disease associated with fibrosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1029. Epub 2018 Sep 13. PMID: 30271345
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Rhubarb
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor
[+]

Urinary metabonomic study of the surface layer of Poria cocos as an effective treatment for chronic renal injury.Jul 08, 2013

Pubmed Data : J Ethnopharmacol. 2013 Jul 9 ;148(2):403-10. Epub 2013 Apr 21. PMID: 23612421
Article Published Date : Jul 08, 2013
Study Type : Animal Study
Additional Links
Substances : Poria cocos
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Renoprotective
[+]

Vitamin K metabolism in a rat model of chronic kidney disease.Dec 31, 2016

Pubmed Data : Am J Nephrol. 2017 ;45(1):4-13. Epub 2016 Nov 16. PMID: 27846632
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Chronic Kidney Disease (CKD), Vitamin K Deficiency
Pharmacological Actions : Renoprotective
[+]

Xanthones protects lead-induced chronic kidney disease.Feb 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Biophys Rep. 2020 Mar ;21:100718. Epub 2019 Dec 10. PMID: 31886417
Article Published Date : Feb 29, 2020
Study Type : Animal Study
Additional Links
Substances : Xanthones
Diseases : Chronic Kidney Disease (CKD), Lead Poisoning
Pharmacological Actions : Antioxidants, NF-kappaB Inhibitor, Nrf2 activation, Renoprotective
Problem Substances : Lead
[+]

Zinc supplementation inhibits the high glucose‑induced EMT of peritoneal mesothelial cells by activating the Nrf2 antioxidant pathway.Jun 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Jul ;20(1):655-663. Epub 2019 May 22. PMID: 31115566
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Zinc
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Antioxidants, Nrf2 activation, Renoprotective
[+]

25-vitamin D reduces inflammation in uremic environment.Jan 09, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Jan 10 ;10(1):128. Epub 2020 Jan 10. PMID: 31924826
Article Published Date : Jan 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Air pollution was observed to be associated with chronic kidney disease and renal function decline.Nov 15, 2019

Pubmed Data : Sci Total Environ. 2019 Nov 16 ;706:135522. Epub 2019 Nov 16. PMID: 31864998
Article Published Date : Nov 15, 2019
Study Type : Review
Additional Links
Diseases : Air Pollution Linked Toxicity, Chronic Kidney Disease (CKD), Kidney Damage
Additional Keywords : Risk Factors
[+]

Astaxanthin counteracts vascular calcification in vitro.Nov 11, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Nov 12 ;21(22). Epub 2020 Nov 12. PMID: 33198315
Article Published Date : Nov 11, 2020
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Chronic Kidney Disease (CKD), Vascular Calcification
Pharmacological Actions : Antioxidants
[+]

Berberine protects against diabetic kidney disease.Nov 15, 2019

Pubmed Data : Br J Pharmacol. 2019 Nov 16. Epub 2019 Nov 16. PMID: 31734944
Article Published Date : Nov 15, 2019
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Chronic Kidney Disease (CKD), Diabetes: Kidney Function , Diabetic Neuropathy
Pharmacological Actions : Antioxidants, Hypolipidemic, Renoprotective
[+]

Bisphenol A is an exogenous toxin that promotes mitochondrial injury and death in tubular cells.Dec 06, 2017

Pubmed Data : Environ Toxicol. 2017 Dec 7. Epub 2017 Dec 7. PMID: 29214717
Article Published Date : Dec 06, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Chronic Kidney Disease (CKD)
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
[+]

Carnosine has a promising potential for the treatment and prevention of different kidney diseases.Jul 29, 2019

Pubmed Data : Curr Med Chem. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31362685
Article Published Date : Jul 29, 2019
Study Type : Review
Additional Links
Substances : Carnosine
Diseases : Chronic Kidney Disease (CKD), Diabetic Nephropathy, Kidney Damage: Chemically-Induced
Pharmacological Actions : Renoprotective
[+]

Chronic inflammation in the etiology of disease across the life span.Nov 30, 2019

Pubmed Data : Nat Med. 2019 Dec ;25(12):1822-1832. Epub 2019 Dec 5. PMID: 31806905
Article Published Date : Nov 30, 2019
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Cancers, Cardiovascular Diseases, Chronic Kidney Disease (CKD), Inflammation, Neurodegenerative Diseases, Nonalcoholic fatty liver disease (NAFLD)
Additional Keywords : Risk Factors
[+]

Coenzyme Q10 supplementation might have promising effects on oxidative stress in chronic kidney disease patients.Mar 28, 2021

Pubmed Data : Int Urol Nephrol. 2021 Mar 29. Epub 2021 Mar 29. PMID: 33782820
Article Published Date : Mar 28, 2021
Study Type : Review
Additional Links
Substances : Coenzyme Q10
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Combined melatonin and poricoic acid A inhibits renal fibrosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ther Adv Chronic Dis. 2019 ;10:2040622319869116. Epub 2019 Aug 14. PMID: 31452866
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
Additional Keywords : Polysaccharides
[+]

Cranberries - potential benefits in patients with chronic kidney disease.Jun 18, 2019

Pubmed Data : Food Funct. 2019 Jun 19 ;10(6):3103-3112. PMID: 31140512
Article Published Date : Jun 18, 2019
Study Type : Review
Additional Links
Substances : Cranberry
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Cruciferous vegetables: rationale for exploring potential salutary effects of sulforaphane-rich foods in patients with chronic kidney disease.Dec 17, 2020

Pubmed Data : Nutr Rev. 2020 Dec 18. Epub 2020 Dec 18. PMID: 33338213
Article Published Date : Dec 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Cruciferous Vegetables, Sulforaphane
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Antioxidants, Nrf2 activation, Renoprotective
[+]

Curcumin has potential for treatment of heart disease in patients with established CKD by attenuating oxidative stress-related cardiac remodeling and mitochondrial dysfunction.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Drugs Ther. 2015 Apr ;29(2):101-3. PMID: 25869394
Article Published Date : Mar 31, 2015
Study Type : Commentary
Additional Links
Substances : Curcumin
Diseases : Cardiovascular Disease: Prevention, Cardiovascular Diseases, Chronic Kidney Disease (CKD), Mitochondrial Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin has significant anti-inflammatory, anti-oxidant and various other features which make it a strong candidate to be included in therapeutic armamentarium for treating CKD.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2014 ;19(12):20139-56. Epub 2014 Dec 2. PMID: 25474287
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Chronic Kidney Disease (CKD), Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

Eicosapentaenoic acid is a potential therapeutic approach to reduce cardiovascular risk in patients with end-stage renal disease on hemodialysis.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiorenal Med. 2017 Dec ;8(1):18-30. Epub 2017 Sep 16. PMID: 29344023
Article Published Date : Nov 30, 2017
Study Type : Review
Additional Links
Substances : EPA (Eicosapentaenoic Acid)
Diseases : Chronic Kidney Disease (CKD), Hemodialysis
Pharmacological Actions : Cardioprotective
[+]

Excess fluoride in drinking water and in the locally grown food in the affected areas might lead to chronic kidney diseases.Jun 30, 2015

Pubmed Data : Environ Health Prev Med. 2015 Jul ;20(4):237-42. Epub 2015 Apr 28. PMID: 25916575
Article Published Date : Jun 30, 2015
Study Type : Commentary
Additional Links
Diseases : Chronic Kidney Disease (CKD), Fluoride Toxicity , Kidney Damage
Additional Keywords : Risk Factors
Problem Substances : Fluoride, Sodium Fluoride
[+]

Exposure to sugar-sweetened beverages may also be involved in the increased risk for chronic kidney disease.May 31, 2015

Pubmed Data : Mayo Clin Proc. 2015 Jun ;90(6):813-23. PMID: 26046414
Article Published Date : May 31, 2015
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Additional Keywords : Risk Factors
Problem Substances : Sugar Sweetened Beverages
[+]

Flos A. manihot was more effective than the angiotensin-receptor blocker losartan in reducing proteinuria in patients with primary glomerular disease.Jan 31, 2016

Pubmed Data : Clin Exp Pharmacol Physiol. 2016 Feb ;43(2):145-8. PMID: 26667396
Article Published Date : Jan 31, 2016
Study Type : Review
Additional Links
Substances : Okra
Diseases : Chronic Kidney Disease (CKD), Proteinuria
Pharmacological Actions : Anti-Apoptotic, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

G. lucidum has been proved to exhibit significant role in preventing and treating various kidney diseases.Dec 31, 2018

Pubmed Data : Adv Exp Med Biol. 2019 ;1182:243-262. PMID: 31777022
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Reishi Mushroom
Diseases : Chronic Kidney Disease (CKD), Kidney Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antioxidants, Antiproliferative , Renoprotective
[+]

Ginsenoside Rb1 could be applied in the treatment of patients with chronic kidney disease.Jul 10, 2020

Pubmed Data : Int J Biol Macromol. 2020 Jul 11 ;163:996-1009. Epub 2020 Jul 11. PMID: 32659400
Article Published Date : Jul 10, 2020
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Glyphosate's synergistic toxicity in combination with other factors as a cause of chronic kidney disease of unknown origin.Jul 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2019 Jul 31 ;16(15). Epub 2019 Jul 31. PMID: 31370256
Article Published Date : Jul 30, 2019
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD), Glyphosate Toxicity, Kidney Damage: Chemically-Induced
Additional Keywords : Synergistic Toxicity
Problem Substances : Glyphosate, Paraquat
[+]

Herbal antioxidants in dialysis patients: a review of potential mechanisms and medical implications.Nov 30, 2021

Pubmed Data : Ren Fail. 2021 Dec ;43(1):351-361. PMID: 33593237
Article Published Date : Nov 30, 2021
Study Type : Review
Additional Links
Substances : Curcumin, Emodin, Quercetin, Resveratrol, Silymarin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Antioxidants
[+]

Inflammation is a key contributor to the genesis and progression of chronic kidney disease.Dec 31, 2016

Pubmed Data : Contrib Nephrol. 2017 ;191:72-83. Epub 2017 Sep 14. PMID: 28910792
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD), Inflammation
Additional Keywords : Risk Factors
[+]

Influence of resveratrol on the cardiovascular health effects of chronic kidney disease.Aug 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Aug 31 ;21(17). Epub 2020 Aug 31. PMID: 32878067
Article Published Date : Aug 30, 2020
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Cardioprotective
[+]

Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Feb 1 ;8(1):2069. Epub 2018 Feb 1. PMID: 29391410
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Magnesium
Diseases : Arterial Calcification, Chronic Kidney Disease (CKD)
[+]

Melatonin induces beneficial effects at numerous pathophysiological levels related to chronic kidney disease.Dec 31, 2014

Pubmed Data : Curr Pharm Des. 2015 ;21(7):936-49. PMID: 25269563
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

Neferine inhibits LPS-ATP-induced endothelial cell pyroptosis.Jun 05, 2019

Pubmed Data : Inflamm Res. 2019 Jun 6. Epub 2019 Jun 6. PMID: 31172209
Article Published Date : Jun 05, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Chronic Kidney Disease (CKD), Endothelial Dysfunction
Pharmacological Actions : Antioxidants
[+]

Niacin and related compounds may have utility for the treatment of both hyperphosphatemia and dyslipidemia in CKD patients to prevent CVD.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2015 ;61 Suppl:S173-5. PMID: 26598845
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Niacin
Diseases : Chronic Kidney Disease (CKD), Dyslipidemias, Hyperphosphatemia
[+]

Oral magnesium supplementation reduces vascular calcification in patients with chronic kidney disease.Apr 30, 2018

Pubmed Data : Adv Chronic Kidney Dis. 2018 May ;25(3):281-290. PMID: 29793668
Article Published Date : Apr 30, 2018
Study Type : Review
Additional Links
Substances : Magnesium
Diseases : Calcification: Arterial, Chronic Kidney Disease (CKD)
[+]

Plant-based diets for prevention and management of chronic kidney disease.Nov 11, 2019

Pubmed Data : Curr Opin Nephrol Hypertens. 2019 Nov 12. Epub 2019 Nov 12. PMID: 31725014
Article Published Date : Nov 11, 2019
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Vegetarian
Pharmacological Actions : Renoprotective
[+]

Plant-based diets should be included as part of the clinical recommendations for both the prevention and management of chronic kidney disease.Jul 04, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nephrol Dial Transplant. 2018 Jul 5. Epub 2018 Jul 5. PMID: 29982610
Article Published Date : Jul 04, 2018
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Vegetarian
Additional Keywords : Risk Reduction
[+]

The current review summarizes the existing in vitro and in vivo animal and human studies examining the nephroprotective effects of resveratrol.Jul 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Jul 17 ;11(7). Epub 2019 Jul 17. PMID: 31319485
Article Published Date : Jul 16, 2019
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Renoprotective
[+]

This review demonstrates the several biological activities of oleuropein including antioxidant, anti-inflammatory and anticancer properties.Nov 21, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Nov 22 ;8(12). Epub 2019 Nov 22. PMID: 31766676
Article Published Date : Nov 21, 2019
Study Type : Review
Additional Links
Substances : Oleuropein
Diseases : Atherosclerosis, Cancers: All, Cardiovascular Diseases, Chronic Kidney Disease (CKD), Colitis, Diabetes Mellitus: Type 2, Hypertension, Inflammation, Neurodegenerative Diseases, Oxidative Stress, Pleurisy
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Antioxidants, Autophagy Up-regulation, Cardioprotective, Neuroprotective Agents, Nrf2 activation
[+]

This reviews the potential mechanisms whereby several key characteristics of the typical Western diet may impact kidney disease incidence and progression.Feb 28, 2015

Pubmed Data : Curr Hypertens Rep. 2015 Mar ;17(3):16. PMID: 25754321
Article Published Date : Feb 28, 2015
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Western Diet

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