Chronic Kidney Disease (CKD)

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11 Substances Researched for Chronic Kidney Disease (CKD)
NameACCKFocus
Fiber120Locked
Turmeric220Locked
Boswellia110Locked
Pomegranate110Locked
Vitamin D110Locked
Amygdalin12Locked
Bee Venom12Locked
Curcumin22Locked
Propolis: Brazillian12Locked
Melatonin11Locked
Niacin11Locked
5 Problem Substances Researched for Chronic Kidney Disease (CKD)
NameACCKFocus
Bisphenol A 110Locked
Statin Drugs110Locked
Fluoride23Locked
Monosodium Glutamate (MSG)12Locked
Sodium Fluoride11Locked
3 Therapeutic Actions Researched for Chronic Kidney Disease (CKD)
NameACCKFocus
Dietary Modification: Low Carbohydrate/Ketogenic110Locked
Dietary Modification: Mediterranean Diet110Locked
Dietary Modification: Vegetarian110Locked

View the Evidence:
80 Abstracts with Chronic Kidney Disease (CKD) Research

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This study summarizes the potential beneficial effects of dietary fiber in the CKD population demonstrating a reduction in serum urea and creatinine.Jun 30, 2015

Pubmed Data : Eur J Clin Nutr. 2015 Jul ;69(7):761-8. Epub 2014 Nov 12. PMID: 25387901
Article Published Date : Jun 30, 2015
Study Type : Meta Analysis, Review
Additional Links
Substances : Fiber
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Renoprotective
Additional Keywords : Risk Reduction
[+]

25OHD deficiency is a risk factor for secondary hyperparathyroidism and decreased serum 1,25(OH)2D in children with CKD.Aug 25, 2015

Pubmed Data : Pediatr Nephrol. 2015 Aug 26. Epub 2015 Aug 26. PMID: 26307635
Article Published Date : Aug 25, 2015
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

A diet rich in vegetables and fruit may reduce the risk for kidney disease.Apr 26, 2019

Pubmed Data : Am J Kidney Dis. 2019 Apr 27. Epub 2019 Apr 27. PMID: 31040089
Article Published Date : Apr 26, 2019
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Chronic Kidney Disease (CKD)
Additional Keywords : Risk Reduction
[+]

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

Pubmed Data : J Altern Complement Med. 2017 Aug ;23(8):632-638. Epub 2017 Apr 4. PMID: 28375641
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Chronic Kidney Disease (CKD), Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

A vitamin D deficiency at baseline is significantly correlated with poorer clinical outcomes and more sever renal pathological features.Nov 01, 2016

Pubmed Data : BMC Nephrol. 2016 Nov 2 ;17(1):164. Epub 2016 Aug 2. PMID: 27806690
Article Published Date : Nov 01, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Adequate consumption of phytate can prevent abdominal aortic calcification in patients with chronic kidney disease.Dec 31, 2015

Pubmed Data : J Ren Nutr. 2016 07 ;26(4):226-36. Epub 2016 Mar 12. PMID: 26975775
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Phytate
Diseases : Aortic Calcification, Chronic Kidney Disease (CKD)
[+]

Adherence to the Mediterranean diet has favourable effects on the prevention of kidney dysfunction.Aug 10, 2016

Pubmed Data : Hypertens Res. 2016 Aug 11. Epub 2016 Aug 11. PMID: 27511053
Article Published Date : Aug 10, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Additional Keywords : Risk Reduction
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Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Kidney J. 2018 Aug ;11(4):532-539. Epub 2018 Feb 6. PMID: 30094018
Article Published Date : Jul 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Antihypertensive Agents
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Ascorbic acid might be a promising agent in chronic kidney disease for improving outcome by decreasing oxidative stress and ADMA levels.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Kidney J. 2018 Aug ;11(4):530-531. Epub 2018 Jun 26. PMID: 30094017
Article Published Date : Jul 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Antioxidants
[+]

Beneficial effects of 6-month supplementation with omega-3 acids on selected inflammatory markers in patients with chronic kidney disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2017 ;2017:1680985. Epub 2017 Nov 19. PMID: 29349065
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents
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Combined sodium bicarbonate and ascorbic acid could prevent contrast-induced nephropathy following catheterization in CKD patients.Jan 24, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Circ J. 2017 Jan 25 ;81(2):235-240. Epub 2016 Dec 22. PMID: 28003574
Article Published Date : Jan 24, 2017
Study Type : Human Study
Additional Links
Substances : Sodium Bicarbonate, Vitamin C
Diseases : Chronic Kidney Disease (CKD), Nephropathy
Pharmacological Actions : Renoprotective
Additional Keywords : Risk Reduction
[+]

Curcumin and Boswellia serrata are safe and tolerable and helped to improvethe levels of an inflammatory cytokine (IL-6).Dec 31, 2012

Pubmed Data : J Complement Integr Med. 2013 ;10(1):1-10. Epub 2013 Jul 1. PMID: 23828329
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Boswellia, Turmeric
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
Additional Keywords : Substance Combination
[+]

Dietary beta-glucans could decrease the levels of the proteolytic uremic toxins p-cresyl sulphate.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(1):e0169635. Epub 2017 Jan 20. PMID: 28107445
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Beta-glucan
Diseases : Chronic Kidney Disease (CKD), Endothelial Dysfunction
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Microbiota
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Effects of Brazilian green propolis on proteinuria and renal function in patients with chronic kidney disease.Apr 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Nephrol. 2019 Apr 25 ;20(1):140. Epub 2019 Apr 25. PMID: 31023272
Article Published Date : Apr 24, 2019
Study Type : Human Study
Additional Links
Substances : Propolis: Brazillian
Diseases : Chronic Kidney Disease (CKD), Proteinuria
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective
[+]

Ginsenoside Rb1 treatment was effective in reducing the extent of oxidative stress and inflammation in chronic kidney disease patients.Jan 31, 2017

Pubmed Data : Inflammopharmacology. 2017 Feb ;25(1):33-40. Epub 2016 Nov 17. PMID: 27853891
Article Published Date : Jan 31, 2017
Study Type : Human Study
Additional Links
Substances : Ginsenosides
Diseases : Chronic Kidney Disease (CKD), Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

High homocysteine, low vitamin B-6, and increased oxidative stress are independently associated with the risk of chronic kidney disease.Jan 31, 2016

Pubmed Data : Nutrition. 2016 Feb ;32(2):236-41. Epub 2015 Sep 25. PMID: 26526964
Article Published Date : Jan 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin B-6
Diseases : Chronic Kidney Disease (CKD), High Homocysteine, Oxidative Stress, Vitamin B6 Depletion
Pharmacological Actions : Antioxidants
Additional Keywords : Risk Factors
[+]

Higher serum magnesium level may be associated with better endothelial function in end stage renal disease patients on hemodialysis.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Yonsei Med J. 2016 Nov ;57(6):1446-53. PMID: 27593873
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Chronic Kidney Disease (CKD), Endothelial Dysfunction, Hemodialysis, Magnesium Deficiency
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Hypovitaminosis D is associated with subclinical peripheral arterial disease, independently of other cardiovascular risk factors.Sep 30, 2016

Pubmed Data : Arch Med Sci. 2016 Oct 1 ;12(5):1015-1022. Epub 2016 Aug 24. PMID: 27695492
Article Published Date : Sep 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Cardiovascular Diseases, Chronic Kidney Disease (CKD), Peripheral Arterial Disease, Vitamin D Deficiency
Additional Keywords : Risk Factors
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Intake of oats may have a beneficial effect on serum albumin and serum potassium in patients with chronic kidney disease.Dec 01, 2016

Pubmed Data : Clin Nutr. 2016 Dec 2. Epub 2016 Dec 2. PMID: 28003041
Article Published Date : Dec 01, 2016
Study Type : Human Study
Additional Links
Substances : Oats
Diseases : Chronic Kidney Disease (CKD)
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Intravenous ascorbic acid could be a new successful adjuvant in reducing ferritin and erythropoietin resistance in chronic kidney disease patients.Jun 30, 2017

Pubmed Data : J Assoc Physicians India. 2017 Jul ;65(7):32-36. PMID: 28792166
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin C: Intravenous
Diseases : Chronic Kidney Disease (CKD)
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Low serum magnesium were independently associated with all-cause death in patients with prevalent chronic kidney disease.Oct 24, 2017

Pubmed Data : Nephrol Dial Transplant. 2017 Oct 25. Epub 2017 Oct 25. PMID: 29077944
Article Published Date : Oct 24, 2017
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Chronic Kidney Disease (CKD), Magnesium Deficiency
Additional Keywords : Risk Factors
[+]

Lower serum calcium is independently associated with chronic kidney disease progression.Mar 25, 2018

Pubmed Data : Sci Rep. 2018 Mar 26 ;8(1):5148. Epub 2018 Mar 26. PMID: 29581540
Article Published Date : Mar 25, 2018
Study Type : Human Study
Additional Links
Substances : Calcium, Vitamin D
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
[+]

Moderate protein restriction in a vegan-vegetarian supplemented diet is confirmed as a safe option in the management of pregnant CKD patients.Sep 19, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Nephrol. 2016 Sep 20 ;17(1):132. Epub 2016 Sep 20. PMID: 27649693
Article Published Date : Sep 19, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Vegan Diet, Dietary Modification: Vegetarian
Additional Keywords : Chronic Kidney Disease (CKD), Pregnancy, pregnant women, Vegan, vegetarian, women's health
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Multiple heavy metals and agrochemicals such as glyphosate and their residues acting synergistically may play a role in the pathogenesis of SAN.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Nephrol. 2015 ;16:103. Epub 2015 Jul 11. PMID: 26162605
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Glyphosate Toxicity, Heavy Metal Toxicity
Additional Keywords : Sri Lankan Agricultural Nephropathy
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Nondiabetic patients with stage 3-4 CKD and vitamin D deficiency, vitamin D supplementation may improve vascular function.Sep 30, 2017

Pubmed Data : J Am Soc Nephrol. 2017 Oct ;28(10):3100-3108. Epub 2017 Jun 30. PMID: 28667080
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Interleukin-6 Downregulation, Vasoprotective
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Oral activated charcoal effectively delays the onset of hyperphosphatemia in patients with chronic kidney disease.Dec 25, 2018

Pubmed Data : J Nephrol. 2018 Dec 26. Epub 2018 Dec 26. PMID: 30588573
Article Published Date : Dec 25, 2018
Study Type : Human Study
Additional Links
Substances : Activated Charcoal
Diseases : Chronic Kidney Disease (CKD), Vascular Calcification
Pharmacological Actions : Renoprotective
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Oral cholecalciferol administration increased 25-hydroxyvitamin D and mildly reduced PTH serum levels.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nephrol Renovasc Dis. 2015;8:151-157. Epub 2015 Nov 19. PMID: 26640388
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
Additional Keywords : Supplementation
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Patients with type 2 diabetes and high levels of serum BPA exhibited about a sevenfold increased risk of developing CKD compared to patients with low levels of serum BPA.Aug 31, 2015

Pubmed Data : Acta Diabetol. 2015 Sep 1. Epub 2015 Sep 1. PMID: 26321107
Article Published Date : Aug 31, 2015
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Diabetes Mellitus: Type 2, Diabetic Nephropathy
Additional Keywords : Increased Risk
Problem Substances : Bisphenol A
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Pilates exercises can be valuable for improvement of chronic kidney disease patients' quality of life.Jan 31, 2019

Pubmed Data : Complement Ther Clin Pract. 2019 Feb ;34:35-40. Epub 2018 Nov 1. PMID: 30712743
Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Quality of Life: Poor
Therapeutic Actions : Pilates
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Pomegranate extract supplementation may reduce BP and increase the antioxidant activity in HD patients.Mar 30, 2015

Pubmed Data : J Med Food. 2015 Mar 31. Epub 2015 Mar 31. PMID: 25826143
Article Published Date : Mar 30, 2015
Study Type : Human Study
Additional Links
Substances : Pomegranate
Diseases : Chronic Kidney Disease (CKD), Hemodialysis
Pharmacological Actions : Antihypertensive Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Proton pump inhibitors use and risk of chronic kidney disease in diabetic patients.Nov 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetes Res Clin Pract. 2018 Nov 27 ;147:67-75. Epub 2018 Nov 27. PMID: 30500543
Article Published Date : Nov 26, 2018
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
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Proton pump inhibitors use is associated with a higher risk of incident chronic kidney disease.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(10):e0204231. Epub 2018 Oct 17. PMID: 30332411
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Kidney Damage: Drug-Induced
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
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Regular ingestion of turmeric reduces plasma malondialdehyde and increases red blood cell catalase activity and plasma albumin levels in hemodialysis patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Hemodial Int. 2015 Jan ;19(1):124-31. Epub 2014 Aug 16. PMID: 25131305
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Chronic Kidney Disease (CKD), Hemodialysis, Oxidative Stress
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Malondialdehyde Down-regulation
Additional Keywords : Significant Treatment Outcome
[+]

S-adenosylmethionine has nephroprotective properties.Nov 30, 2017

Pubmed Data : Georgian Med News. 2017 Dec(273):31-36. PMID: 29328026
Article Published Date : Nov 30, 2017
Study Type : Human Study
Additional Links
Substances : S-Adenosylmethionine (SAMe)
Diseases : Chronic Kidney Disease (CKD), Liver Steatosis, Obesity
Pharmacological Actions : Antioxidants, Renoprotective
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Six months yoga program is safe and effective as an adjuvant therapy in improving renal functions and QOL of CKD patients.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Yoga. 2017 Jan-Apr;10(1):3-8. PMID: 28149061
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Quality of Life: Poor
Pharmacological Actions : Antihypertensive Agents
Additional Keywords : Antihypertensive Agents, Chronic Kidney Disease (CKD), Quality of Life: Poor, yoga
[+]

Sodium bicarbonate supplementation is associated with a decrease in electronegative LDL in chronic kidney disease patients.Sep 30, 2017

Pubmed Data : Cardiorenal Med. 2017 Oct ;7(4):334-341. Epub 2017 Aug 17. PMID: 29118772
Article Published Date : Sep 30, 2017
Study Type : Human Study
Additional Links
Substances : Sodium Bicarbonate
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Hypolipidemic, Renoprotective
[+]

Stevia has the potential for a significant improvement of some biochemical parameters in chronic kidney disease patients.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Contemp Clin Trials Commun. 2018 Dec ;12:17-25. Epub 2018 Aug 21. PMID: 30211340
Article Published Date : Nov 30, 2018
Study Type : Human Study
Additional Links
Substances : Stevia
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Hypoglycemic Agents, Renoprotective, Uricosuric Agents
[+]

Taking proton pump inhibitors is associated with a small excess of cause specific mortality.Jan 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ. 2019 05 29 ;365:l1580. Epub 2019 May 29. PMID: 31147311
Article Published Date : Jan 28, 2019
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Chronic Kidney Disease (CKD), Gastrointestinal Cancer
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

The ketogenic diet seems nutritionally safe and could defer dialysis initiation in some patients with chronic kidney disease.Jan 27, 2016

Pubmed Data : J Am Soc Nephrol. 2016 Jan 28. Epub 2016 Jan 28. PMID: 26823552
Article Published Date : Jan 27, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Dietary Modification: Vegetarian
Pharmacological Actions : Renoprotective
Additional Keywords : Risk Reduction
[+]

This study demonstrated the association between vitamin D deficiency and depression in CKD patients.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(2):e0171009. Epub 2017 Feb 13. PMID: 28192445
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Depression, Vitamin D Deficiency
[+]

This study found that patients with chronic kidney disease and taking statins had lower 25-OH-D3 levels. Feb 28, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nefrologia. 2015 Mar-Apr;35(2):150-6. Epub 2015 Jun 23. PMID: 26300508
Article Published Date : Feb 28, 2015
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Drug-Induced Nutrient Depletion: Statin Drugs, Vitamin D Deficiency
Problem Substances : Statin Drugs
[+]

Vitamin D and folic acid are universally deficient in the diets of patients with chronic kidney disease.May 31, 2016

Pubmed Data : Transplant Proc. 2016 Jun ;48(5):1427-30. PMID: 27496421
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Folic Acid/Folate Deficiency, Vitamin D Deficiency
[+]

Allicin showed an antihypertensive, nephroprotective, cardioprotective, and antioxidant effects.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:3850402. Epub 2016 Nov 21. PMID: 27990229
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Chronic Kidney Disease (CKD), Hypertension, Oxidative Stress
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Cardioprotective, Renoprotective
[+]

Amygdalin is a potent antifibrotic agent that may have therapeutic potential for patients with fibrotic kidney diseases.Apr 30, 2013

Pubmed Data : Mol Med Rep. 2013 May ;7(5):1453-7. Epub 2013 Mar 22. PMID: 23525378
Article Published Date : Apr 30, 2013
Study Type : Animal Study
Additional Links
Substances : Amygdalin
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Antiproliferative , Renoprotective
[+]

Asiatic acid and naringenin may represent as a novel and effective therapy for chronic kidney disease associated with fibrosis.Nov 09, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Nov 10 ;6(35):36984-97. PMID: 26474462
Article Published Date : Nov 09, 2015
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid, Naringenin
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Astragaloside IV improves renal function and fibrosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2018 ;12:2431-2442. Epub 2018 Aug 6. PMID: 30122901
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Chronic Kidney Disease (CKD), Diabetic Complications, Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Bee venom may be a useful therapeutic agent for the prevention of fibrosis that characterizes progression of chronic kidney disease.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2015 Jun ;7(6):1917-28. Epub 2015 May 29. PMID: 26035488
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Brazilian red propolis treatment attenuated hypertension and structural renal damage in a renal ablation model.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(1):e0116535. Epub 2015 Jan 21. PMID: 25607548
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Propolis: Brazillian
Diseases : Chronic Kidney Disease (CKD), Hypertension
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Antioxidants, Renoprotective
[+]

Chronic monosodium glutamate (MSG) intake causes kidney dysfunction and renal oxidative stress in the animal model.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(12):e116233. Epub 2014 Dec 31. PMID: 25551610
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Kidney Damage, Kidney Failure: Chronic
Problem Substances : Monosodium Glutamate (MSG)
[+]

Curcuma aromatica oil administration ameliorates renal fibrosis symptoms by inhibiting metabolic pathways, lipid metabolism, glycolysis and methylamine metabolism.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(9):e108678. Epub 2014 Sep 29. PMID: 25265289
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective
[+]

Curcumin exhibits salutary effects against adenine-induced chronic kidney disease in rats by reducing inflammation and oxidative stress.May 30, 2017

Pubmed Data : Basic Clin Pharmacol Toxicol. 2017 May 31. Epub 2017 May 31. PMID: 28561324
Article Published Date : May 30, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation
[+]

Diesel exhaust particles worsen renal oxidative stress, inflammation and DNA damage in mice with adenine-induced chronic renal failure.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2016 ;38(5):1703-13. Epub 2016 May 3. PMID: 27160713
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Diesel Exhaust Particle Toxicity , DNA damage, Oxidative Stress
[+]

Effect of water fluoridation on the development of medial vascular calcification in uremic rats.Apr 05, 2014

Pubmed Data : Toxicology. 2014 Apr 6 ;318:40-50. Epub 2014 Feb 18. PMID: 24561004
Article Published Date : Apr 05, 2014
Study Type : Animal Study
Additional Links
Diseases : Arterial Calcification, Atheroma, Atherosclerosis, Chronic Kidney Disease (CKD), Ectopic Calcification, Fluoride Toxicity
Problem Substances : Fluoride
Adverse Pharmacological Actions : Cardiotoxic
[+]

Fucoidan improves bioactivity and vasculogenic potential of mesenchymal stem cells in murine hind limb ischemia associated with chronic kidney disease.Dec 31, 2015

Pubmed Data : J Mol Cell Cardiol. 2016 08 ;97:169-79. Epub 2016 May 20. PMID: 27216370
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Chronic Kidney Disease (CKD), Ischemia
Additional Keywords : Mesenchymal Stem Cells
[+]

Low-molecular-weight polysaccharides of Inonotus obliquus may be advantageous to control the progression of CKD.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(9). Epub 2016 Sep 13. PMID: 27649140
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Chronic Kidney Disease (CKD), Diabetic Nephropathy
Pharmacological Actions : NF-kappaB Inhibitor, Renoprotective
[+]

Oligo-fucoidan prevents renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway.Jan 17, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 01 18 ;7:40183. Epub 2017 Jan 18. PMID: 28098144
Article Published Date : Jan 17, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Chronic Kidney Disease (CKD), Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

Rescue therapy with tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease.Jan 17, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 11 18 ;6:36698. Epub 2016 Nov 18. PMID: 27857162
Article Published Date : Jan 17, 2016
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : anti-inflammatory, Renoprotective
[+]

Tangeretin effectively improved renal function and reduced the cognitive and memory impairments in chronic kidney disease.Sep 03, 2017

Pubmed Data : Inflammopharmacology. 2017 Sep 4. Epub 2017 Sep 4. PMID: 28871498
Article Published Date : Sep 03, 2017
Study Type : Animal Study
Additional Links
Substances : Tangeretin
Diseases : Chronic Kidney Disease (CKD), Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tanshinone IIA might be a novel therapy for preventing progression of chronic kidney disease after acute kidney injury.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:867140. Epub 2015 Dec 29. PMID: 26885500
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chronic Kidney Disease (CKD), Kidney Damage
Pharmacological Actions : Renoprotective
[+]

The beneficial effects of allicin in chronic kidney disease are comparable to losartan.Sep 15, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Sep 16 ;18(9). Epub 2017 Sep 16. PMID: 28926934
Article Published Date : Sep 15, 2017
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Renoprotective
Additional Keywords : Natural Substances Versus Drugs
[+]

These results indicated that ozone therapy might reduce sterile renal inflammation and slow down chronic kidney disease progression.Jan 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Feb ;43:203-209. Epub 2016 Dec 27. PMID: 28038382
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Chronic Kidney Disease (CKD), Inflammation
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective
[+]

Treatment with rhubarb extracts may represent as an effective therapy for chronic kidney disease associated with fibrosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1029. Epub 2018 Sep 13. PMID: 30271345
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Rhubarb
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor
[+]

Vitamin K metabolism in a rat model of chronic kidney disease.Dec 31, 2016

Pubmed Data : Am J Nephrol. 2017 ;45(1):4-13. Epub 2016 Nov 16. PMID: 27846632
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Chronic Kidney Disease (CKD), Vitamin K Deficiency
Pharmacological Actions : Renoprotective
[+]

Bisphenol A is an exogenous toxin that promotes mitochondrial injury and death in tubular cells.Dec 06, 2017

Pubmed Data : Environ Toxicol. 2017 Dec 7. Epub 2017 Dec 7. PMID: 29214717
Article Published Date : Dec 06, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Chronic Kidney Disease (CKD)
Additional Keywords : Risk Factors
Problem Substances : Bisphenol A
[+]

Cranberries - potential benefits in patients with chronic kidney disease.Jun 18, 2019

Pubmed Data : Food Funct. 2019 Jun 19 ;10(6):3103-3112. PMID: 31140512
Article Published Date : Jun 18, 2019
Study Type : Review
Additional Links
Substances : Cranberry
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Curcumin has potential for treatment of heart disease in patients with established CKD by attenuating oxidative stress-related cardiac remodeling and mitochondrial dysfunction.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Drugs Ther. 2015 Apr ;29(2):101-3. PMID: 25869394
Article Published Date : Mar 31, 2015
Study Type : Commentary
Additional Links
Substances : Curcumin
Diseases : Cardiovascular Disease: Prevention, Cardiovascular Diseases, Chronic Kidney Disease (CKD), Mitochondrial Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin has significant anti-inflammatory, anti-oxidant and various other features which make it a strong candidate to be included in therapeutic armamentarium for treating CKD.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2014 ;19(12):20139-56. Epub 2014 Dec 2. PMID: 25474287
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Chronic Kidney Disease (CKD), Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

Eicosapentaenoic acid is a potential therapeutic approach to reduce cardiovascular risk in patients with end-stage renal disease on hemodialysis.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiorenal Med. 2017 Dec ;8(1):18-30. Epub 2017 Sep 16. PMID: 29344023
Article Published Date : Nov 30, 2017
Study Type : Review
Additional Links
Substances : EPA (Eicosapentaenoic Acid)
Diseases : Chronic Kidney Disease (CKD), Hemodialysis
Pharmacological Actions : Cardioprotective
[+]

Excess fluoride in drinking water and in the locally grown food in the affected areas might lead to chronic kidney diseases.Jun 30, 2015

Pubmed Data : Environ Health Prev Med. 2015 Jul ;20(4):237-42. Epub 2015 Apr 28. PMID: 25916575
Article Published Date : Jun 30, 2015
Study Type : Commentary
Additional Links
Diseases : Chronic Kidney Disease (CKD), Fluoride Toxicity , Kidney Damage
Additional Keywords : Risk Factors
Problem Substances : Fluoride, Sodium Fluoride
[+]

Exposure to sugar-sweetened beverages may also be involved in the increased risk for chronic kidney disease.May 31, 2015

Pubmed Data : Mayo Clin Proc. 2015 Jun ;90(6):813-23. PMID: 26046414
Article Published Date : May 31, 2015
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Additional Keywords : Risk Factors
Problem Substances : Sugar Sweetened Beverages
[+]

Glyphosate's synergistic toxicity in combination with other factors as a cause of chronic kidney disease of unknown origin.Jul 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2019 Jul 31 ;16(15). Epub 2019 Jul 31. PMID: 31370256
Article Published Date : Jul 30, 2019
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD), Glyphosate Toxicity, Kidney Damage: Chemically-Induced
Additional Keywords : Synergistic Toxicity
Problem Substances : Glyphosate, Paraquat
[+]

Inflammation is a key contributor to the genesis and progression of chronic kidney disease.Dec 31, 2016

Pubmed Data : Contrib Nephrol. 2017 ;191:72-83. Epub 2017 Sep 14. PMID: 28910792
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD), Inflammation
Additional Keywords : Risk Factors
[+]

Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Feb 1 ;8(1):2069. Epub 2018 Feb 1. PMID: 29391410
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Magnesium
Diseases : Arterial Calcification, Chronic Kidney Disease (CKD)
[+]

Melatonin induces beneficial effects at numerous pathophysiological levels related to chronic kidney disease.Dec 31, 2014

Pubmed Data : Curr Pharm Des. 2015 ;21(7):936-49. PMID: 25269563
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
[+]

Neferine inhibits LPS-ATP-induced endothelial cell pyroptosis.Jun 05, 2019

Pubmed Data : Inflamm Res. 2019 Jun 6. Epub 2019 Jun 6. PMID: 31172209
Article Published Date : Jun 05, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Chronic Kidney Disease (CKD), Endothelial Dysfunction
Pharmacological Actions : Antioxidants
[+]

Niacin and related compounds may have utility for the treatment of both hyperphosphatemia and dyslipidemia in CKD patients to prevent CVD.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2015 ;61 Suppl:S173-5. PMID: 26598845
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Niacin
Diseases : Chronic Kidney Disease (CKD), Dyslipidemias, Hyperphosphatemia
[+]

Oral magnesium supplementation reduces vascular calcification in patients with chronic kidney disease.Apr 30, 2018

Pubmed Data : Adv Chronic Kidney Dis. 2018 May ;25(3):281-290. PMID: 29793668
Article Published Date : Apr 30, 2018
Study Type : Review
Additional Links
Substances : Magnesium
Diseases : Calcification: Arterial, Chronic Kidney Disease (CKD)
[+]

Plant-based diets should be included as part of the clinical recommendations for both the prevention and management of chronic kidney disease.Jul 04, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nephrol Dial Transplant. 2018 Jul 5. Epub 2018 Jul 5. PMID: 29982610
Article Published Date : Jul 04, 2018
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Therapeutic Actions : Dietary Modification: Vegetarian
Additional Keywords : Risk Reduction
[+]

The current review summarizes the existing in vitro and in vivo animal and human studies examining the nephroprotective effects of resveratrol.Jul 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 Jul 17 ;11(7). Epub 2019 Jul 17. PMID: 31319485
Article Published Date : Jul 16, 2019
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Renoprotective
[+]

This reviews the potential mechanisms whereby several key characteristics of the typical Western diet may impact kidney disease incidence and progression.Feb 28, 2015

Pubmed Data : Curr Hypertens Rep. 2015 Mar ;17(3):16. PMID: 25754321
Article Published Date : Feb 28, 2015
Study Type : Review
Additional Links
Diseases : Chronic Kidney Disease (CKD)
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Western Diet

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