Cognitive Decline/Dysfunction

Name	AC	CK
Ginkgo biloba	9	92
Vitamin D	9	64
Bacopa	15	53
Omega-3 Fatty Acids	7	53
Vitamin B-12	6	52
Blueberry	10	51
Folic Acid	5	50
DHA (Docosahexaenoic Acid)	6	34
Phosphatidylserine	4	32
Vegetables: All	3	31
EPA (Eicosapentaenoic Acid)	3	30
Lutein	3	30
Pycnogenol (Pine Bark)	3	30
Vitamin B-6	3	30
Vitamin C	7	30
Zeaxanthin	3	30
Astaxanthin	7	28
Green Tea	5	26
Probiotics	6	25
Flavonoids	4	24
Vitamin E	4	24
Nuts	3	21
Black Tea	2	20
Chocolate	2	20
Coffee	1	20
Curcumin	11	20
Fruit: All	1	20
Grape	6	20
Polyunsaturated Fatty Acids (PUFAs)	2	20
Valerian	2	20
Ashwagandha	5	18
Polyphenols	5	18
Resveratrol	5	18
Melatonin	4	16
Nigella sativa (aka Black Seed)	4	16
Ginsenosides	8	15
Magnesium	4	15
Frankincense	3	14
Olive Oil	3	14
Strawberry	3	14
Coconut Oil	2	13
Medium Chain Triglycerides	2	13
Almond	2	12
Berries: All	2	12
Holy Basil	2	12
Lavender	2	12
Lion's Mane (Hericium Erinaceus)	2	12
Pomegranate	2	12
Caffeine	2	11
Antioxidant formulas	1	10
Bergamot orange	1	10
Blue Honeysuckle	1	10
Chlorogenic Acid	1	10
Cholesterol	1	10
Cocoa	1	10
Coconut	1	10
Codonopsis pilosula	1	10
Cruciferous Vegetables	1	10
Fish Oil	1	10
Folate	1	10
Ginger	1	10
Green Leafy Vegetables	1	10
Kava Kava	1	10
Lemon Balm	1	10
Monounsaturated fatty acids	1	10
Multivitamin	1	10
Oats	1	10
Orange	1	10
Peanut	1	10
Rosemary	1	10
Sage	1	10
Sea Cucumber	1	10
Sesamin	1	10
Sulforaphane	5	10
Thiamine (B-1)	1	10
Ubiquinol	1	10
Vitamin E: alpha tocopherol	1	10
Wine	1	10
Nobiletin	5	9
Berberine	4	8
Delta-tetrahydrocannabinol (THC)	4	8
Huperzine	4	8
Ellagic Acid	3	6
Pterostilbene	3	6
Puerarin	3	6
Walnut	3	6
Citrus Peel	3	5
Coenzyme Q10	3	5
Lotus	3	5
Alpha-Lipoic Acid	2	4
Apples	2	4
Asiatic Acid	2	4
Capparis spinosa (caper)	2	4
Krill	2	4
Piperine	2	4
Quercetin	2	4
Sea buckthorn	2	4
Sesamol	2	4
Spinach	2	4
Sweet Potato: Purple	2	4
Caprylic Acid	1	3
Chrysin	2	3
Orange: Mandarin	2	3
Tangeretin	2	3
Theanine	2	3
Acai	1	2
Acetyl-l-carnitine	1	2
Anthocyanins	1	2
Apigenin	1	2
Astragaloside	1	2
Bamboo	1	2
Beta Sitosterol	1	2
Betulinic acid	1	2
Bifidobacterium Breve	1	2
Bifidobacterium Longum	1	2
Black Pepper	1	2
Blackberry	1	2
Boron	2	2
Broccoli Sprouts	1	2
Cannabidiol	1	2
Cannabis	1	2
Carob	1	2
Carrot	1	2
Carvacrol	1	2
Catechin	1	2
Chinese Skullcap	1	2
Crocetin	1	2
Cryptoxanthin	1	2
Curcuma Longa	1	2
Dill	1	2
Diosmin	1	2
EGCG (Epigallocatechin gallate)	1	2
False Black Pepper	1	2
Fig	1	2
Fucoxanthin	1	2
Garlic	1	2
Genistein	1	2
Gingerol	1	2
Ginseng	1	2
Ginseng (Korean)	1	2
Glycyrrhizin	1	2
Gotu Kola	1	2
Guarana	1	2
Hesperidin	1	2
Honokiol	1	2
Icariin	1	2
Kudzu	1	2
Lactobacillus probiotics	1	2
Lavender: Essential Oil	1	2
Lycopene	1	2
Mangiferin	1	2
Moringa oleifera	1	2
Myricetin	1	2
NAC (N-acetyl-L-cysteine)	1	2
Nettle	1	2
Nicotinamide adenine dinucleotide (NADH)	1	2
Noni	1	2
Perilla	1	2
Persimmon	1	2
Plum	1	2
Prickly Pear Cactus	1	2
Procyanidin B2	1	2
Pueraria mirifica	1	2
Purslane	1	2
Raisins	1	2
Rooibos	1	2
Royal Jelly	1	2
Rutin	1	2
Selenium	1	2
Spikenard	1	2
Spirulina	1	2
Syrian rue	1	2
Tanshinone IIA	1	2
Thymol	1	2
Turmeric: Fermented	1	2
Ume (Japanese apricot)	1	2
Vanillin	1	2
Water: Deep Sea	1	2
Water: Deuterium Depleted	1	2
Xanthohumol	1	2
2,3,5,4'-tetrahydroxystilbene-2-O-β -D-glucoside (THSG)	1	1
B-complex	1	1
Beet	1	1
Butyrate	1	1
Docosahexaenoic acid (DHA)	1	1
Fermented Foods and Beverages	1	1
Fiber	1	1
Luteolin	1	1
Prebiotics	1	1
Propolis: Brazillian	1	1
Rhodiola (Tibetan Ginseng)	1	1
Tart Cherry	1	1

Name	AC	CK
Fluoride	3	42
Tamoxifen	3	40
Statin Drugs	5	33
Simvastatin	4	24
Thimerosal	1	20
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	2	12
Lovastatin	2	11
Aluminum Hydroxide	1	10
Arimidex	1	10
Fructose	1	10
Pesticides	1	10
Polychlorinated biphenyls (PCBs)	1	10
Pravastatin	1	10
Raloxifene	1	10
Sucrose	1	10
Aluminum	3	6
Aluminum Chloride	2	4
Atorvastatin	2	3
Acrylamide	1	2
Antibiotics	1	2
Aspartame	1	2
Bisphenol A	1	2
Cyclophosphamide	1	2
Doxorubicin	1	2
Formaldehyde	1	2
Lead	1	2
Monosodium Glutamate (MSG)	1	2
Nicotine	1	2
Trans Fatty Acids	1	2
Alcohol Consumption	1	1
Cholesterol Lowering Drugs	1	1
Ethanol	1	1
High Fructose Corn Syrup	1	1

Name	AC	CK
Exercise	29	198
Exercise: Aerobic	5	51
Dietary Modification: Mediterranean Diet	5	41
Tai Chi	3	30
Acupuncture	3	22
Music	3	21
Meditation	2	20
Sunlight exposure	2	20
Laser Treatment: Low-Level	3	13
Integrative Medicine	2	11
Acupuncture: auricular	1	10
Aromatherapy	1	10
Chiropractic treatment	1	10
Dancing	1	10
Exercise: Cycling	1	10
Gum Chewing	1	10
Kundalini Yoga	1	10
Mantra	1	10
Mindfullness Training	1	10
Qigong	1	10
Shinrin-yoku (taking in the atmosphere of the forest)	1	10
Sunlight Exposure: UVB Light	1	10
Therapeutic Breathing	1	10
Yogic Breathing	1	10
Fasting/Caloric Restriction	3	6
Dietary Modification: Low Carbohydrate/Ketogenic	1	2
Electroacupuncture	1	2
Cognitive Behavioural Approaches	1	1
Drumming	1	1
Hyperbaric Treatment	1	1
Yoga	1	1

Name	AC	CK
Chemotherapy	2	12
Artifical Lighting	1	10
Vaccination: All	1	10
Vaccination: HPV (Gardasil)	1	10
Shift Work	1	2
Western Diet	1	1

Additional Keywords : Risk Reduction

[+]

Meta-analytic findings suggested overall benefits of EGb 761 for stabilizing or slowing decline in cognition of subjects with cognitive impairment and dementia.Dec 31, 2014

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Pubmed Data : J Alzheimers Dis. 2015 ;43(2):605-11. PMID: 25352453

Article Published Date : Dec 31, 2014

Study Type : Meta Analysis

Additional Links

Substances : Ginkgo biloba

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Dementia

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Plant Extracts, Significant Treatment Outcome

[+]

People with various levels of cognitive impairment can benefit from supervised multi-modal exercise.Dec 26, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Neurol India. 2016 Jan-Feb;64(1):56-61. PMID: 26754993

Article Published Date : Dec 31, 2015

Study Type : Meta Analysis, Review

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dementia, Inflammation, Rheumatoid Arthritis

Additional Keywords : Increased Risk

[+]

This meta-analysis suggests that physical activity interventions positively influence cognitive function in patients with dementia.Dec 31, 2015

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Pubmed Data : Ageing Res Rev. 2016 Jan ;25:13-23. Epub 2015 Nov 28. PMID: 26607411

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Pubmed Data : J Prim Prev. 2018 Jan 5. Epub 2018 Jan 5. PMID: 29305752

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Pubmed Data : Am J Clin Nutr. 2006 Feb;83(2):355-61. PMID: 16469995

Article Published Date : Feb 01, 2006

Study Type : Human Study

Additional Links

Substances : Green Tea

Diseases : Cognitive Decline/Dysfunction

[+]

A lack of attention and concentration may occur in subjects who talk on mobile phones for longer times, compared to those who use phones relatively less.Sep 30, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Microsc Ultrastruct. 2017 Oct-Dec;5(4):191-197. Epub 2017 Jul 13. PMID: 30023254

Article Published Date : Sep 30, 2017

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Anti Therapeutic Actions : Electromagnetic Fields, Electromagnetic Radiation, Mobile Phone Radiation

[+]

A Mediterranean diet supplemented with olive oil or nuts is associated with improved cognitive function in older populations. Jun 30, 2015

Article Published Date : Jan 31, 2013

Study Type : Human Study

Additional Links

Diseases : Aging, Cognitive Decline/Dysfunction, Periodontal Diseases

Additional Keywords : Diseases that are Linked

[+]

Aerobic fitness may have a positive influence on protection of brain even in aMCI CSF biomarker, a high-risk population to convert to AD.May 31, 2016

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Pubmed Data : Age (Dordr). 2016 Jun ;38(3):51. Epub 2016 Apr 23. PMID: 27106271

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Pubmed Data : J Diet Suppl. 2017 Nov 2 ;14(6):599-612. Epub 2017 Feb 21. PMID: 28471731

Article Published Date : Nov 01, 2017

Study Type : Human Study

Additional Links

Substances : Ashwagandha

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Assessment of cognitive impairment and its correlation with vitamin D levels patients on maintenance hemodialysis.Feb 29, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Alzheimers Dis. 2019 Oct 29. Epub 2019 Oct 29. PMID: 31683483

Article Published Date : Oct 28, 2019

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Cycling in appears to improve some aspects of cognitive function and mental health.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2019 ;14(2):e0211779. Epub 2019 Feb 20. PMID: 30785893

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Pubmed Data : Pathophysiology. 2012 Apr ;19(2):95-100. Epub 2012 Mar 27. PMID: 22458999

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Nutrients. 2019 Nov 26 ;11(12). Epub 2019 Nov 26. PMID: 31779179

Article Published Date : Nov 25, 2019

Study Type : Human Study

Additional Links

Substances : Vitamin D, Yoghurt

Diseases : Aging: Brain , Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Reduction

[+]

G. biloba seemed to slow down the cognitive deterioration in patients with vascular cognitive impairment.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Electromagn Biol Med. 2015 Sep ;34(3):262-4. PMID: 26444203

Article Published Date : Sep 01, 2015

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dizziness, Fatigue, Headache, Sleep Disorders

Anti Therapeutic Actions : Electromagnetic Fields, Electromagnetic Radiation

[+]

Click here to read the entire abstract

Pubmed Data : Neurobiol Aging. 2006 Nov;27(11):1694-704. Epub 2005 Oct 26. PMID: 16256248

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Monounsaturated fatty acids, Polyunsaturated Fatty Acids (PUFAs)

Diseases : Cognitive Decline/Dysfunction

Therapeutic Actions : Dietary Modification: Mediterranean Diet

[+]

Higher intake of flavonoids, particularly from berries, appears to reduce rates of cognitive decline in older adults.Jun 30, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ann Neurol. 2012 Jul ;72(1):135-43. Epub 2012 Apr 26. PMID: 22535616

Article Published Date : Jun 30, 2012

Study Type : Human Study

Additional Links

Substances : Berries: All, Blueberry, Flavonoids, Strawberry

Diseases : Aging, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Reduction

[+]

Higher intake of polyunsaturated fatty acids (PUFA) and fish oil was associated with better semantic memory and global cognitive function. Jul 01, 2008

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Pubmed Data : Int J Geriatr Psychiatry. 2008 Jul;23(7):741-7. PMID: 18188871

Article Published Date : Jul 01, 2008

Study Type : Human Study

Additional Links

Substances : Polyunsaturated Fatty Acids (PUFAs)

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

[+]

Higher levels of cardiorespiratory fitness are associated with better white matter fiber integrity.Dec 31, 2017

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Pubmed Data : J Alzheimers Dis. 2018 ;61(2):729-739. PMID: 29226864

Article Published Date : Dec 31, 2017

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Pubmed Data : Br J Nutr. 2011 Jun 1:1-10. Epub 2011 Jun 1. PMID: 21736803

Article Published Date : Jun 01, 2011

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Intelligence Quotient (IQ): Low/Impaired, Learning disorders

Problem Substances : Fructose, Sucrose

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Alzheimers Dis. 2016 Mar 11. Epub 2016 Mar 11. PMID: 26967227

Article Published Date : Mar 10, 2016

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Dementia, Sitting Sickness

Therapeutic Actions : Exercise

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Factors, Risk Reduction

[+]

Inflammation and altered endothelial function may play roles in domain-specific cognitive decline of non-demented individuals.Aug 12, 2016

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Pubmed Data : J Gerontol A Biol Sci Med Sci. 2016 Aug 13. Epub 2016 Aug 13. PMID: 27522059

Article Published Date : Aug 12, 2016

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Inflammation

[+]

Inflammation is particularly detrimental in inactive older adults and may exacerbate the negative effects of physical inactivity on brain.May 08, 2016

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Pubmed Data : Hum Brain Mapp. 2016 May 9. Epub 2016 May 9. PMID: 27159568

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Pubmed Data : Int Psychogeriatr. 2017 Jan 16:1-11. Epub 2017 Jan 16. PMID: 28088925

Article Published Date : Jan 15, 2017

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Therapeutic Actions : Kundalini Yoga

Additional Keywords : Significant Treatment Outcome

[+]

Large numbers of young people report impaired concentration and headache. The authors conclude electromagnetic field exposure cannot be ruled out.Oct 01, 2005

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Pubmed Data : Pol Merkur Lekarski. 2005 Oct ;19(112):529-32. PMID: 16379318

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Pubmed Data : J Inorg Biochem. 2009 Nov ;103(11):1571-8. Epub 2009 Aug 20. PMID: 19748679

Article Published Date : Oct 31, 2009

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Pubmed Data : Cureus. 2020 Feb 13 ;12(2):e6976. Epub 2020 Feb 13. PMID: 32206454

Article Published Date : Feb 12, 2020

Study Type : Human Study

Additional Links

Substances : Vitamin B-12

Diseases : Cognitive Decline/Dysfunction, Dementia, Vitamin B 12 Deficiency

Pharmacological Actions : Neuroprotective Agents

[+]

Low vitamin D level was associated with greater risk of cognitive impairment in older as well as younger adults.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Neurophysiol. 2015 Apr 1 ;113(7):2753-9. Epub 2015 Feb 18. PMID: 25695646

Click here to read the entire abstract

Pubmed Data : Bioelectromagnetics. 2009 Dec ;30(8):678-86. PMID: 19644978

Article Published Date : Dec 01, 2009

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Anti Therapeutic Actions : Electromagnetic Fields, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation, Wi-Fi Radiation

Problem Substances : Cell Phone Exposure

[+]

Moderate intensity of aerobic exercise can improve cognitive function in patients with mild Alzheimer's disease.Dec 31, 2014

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Pubmed Data : CNS Neurol Disord Drug Targets. 2015 ;14(10):1292-7. PMID: 26556080

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Therapeutic Actions : Exercise: Aerobic, Exercise: Cycling

[+]

Multi-nutrient supplementation improved cognition and mobility in able older females at clinically relevant levels.Jan 31, 2016

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Pubmed Data : J Gerontol A Biol Sci Med Sci. 2016 Feb ;71(2):236-42. Epub 2015 Aug 11. PMID: 26265727

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Pubmed Data : Neuroimage. 2016 May 1 ;131:226-38. Epub 2015 Oct 1. PMID: 26433119

Article Published Date : Apr 30, 2016

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Therapeutic Actions : Exercise: Aerobic, Integrative Medicine

Pharmacological Actions : Neuroprotective Agents

[+]

Participants randomized to the probiotic group will show greater improvements in psychological status compared to participants in the placebo group.Nov 30, 2018

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Pubmed Data : Contemp Clin Trials Commun. 2018 Dec ;12:192-197. Epub 2018 Nov 14. PMID: 30511028

Article Published Date : Nov 30, 2018

Study Type : Human Study

Additional Links

Substances : Probiotics

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease.Nov 19, 2019

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Pubmed Data : Brain. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31746986

Article Published Date : Nov 19, 2019

Study Type : Human Study

Additional Links

Diseases : Air Pollution Linked Toxicity, Alzheimer's Disease, Cognitive Decline/Dysfunction

[+]

People with the heaviest opioid or NSAID use had slightly higher dementia risk than people with little or no use.Jul 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Am Geriatr Soc. 2015 Aug ;63(8):1519-26. PMID: 26289681

Article Published Date : Jul 31, 2015

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Dementia

Additional Keywords : Risk Factors

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

Periodontitis was associated with an increase in cognitive decline in Alzheimer’s Disease.Dec 31, 2015

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Pomegranate juice augments memory and FMRI activity in middle-aged and older adults with mild memory complaints.Dec 31, 2012

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Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:946298. Epub 2013 Jul 22. PMID: 23970941

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Pubmed Data : J Neurosurg Sci. 2015 Dec ;59(4):437-46. PMID: 26635191

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Neurosci. 2018 Feb 21:1-7. Epub 2018 Feb 21. PMID: 29384421

Article Published Date : Feb 20, 2018

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Multiple Sclerosis

Additional Keywords : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Multiple Sclerosis, Risk Factors

[+]

Serum Vitamin D deficiency was associated with mild cognitive impairment and dementia.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Rev Invest Clin. 2019 ;71(6):381-386. PMID: 31823966

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Dementia, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Short term electromagnetic field exposure may not have an effect on mood, cognitive function, sleep, or overall wellbeing.Jul 01, 2015

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Pubmed Data : Environ Res. 2015 Jul ;140:85-94. Epub 2015 Mar 31. PMID: 25839715

[+]

Superior effects of modified Chen-Style Tai Chi versus 24-style Tai Chi on cognitive function, fitness, and balance performance in adults over 55.May 03, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Neurorehabil Neural Repair. 2018 Feb ;32(2):142-149. Epub 2018 Jan 20. PMID: 29353543

Article Published Date : Jan 31, 2018

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Therapeutic Actions : Tai Chi

Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents

[+]

Tai chi qigong can be considered a useful non-pharmacological approach for improving sleep quality in older adults with cognitive impairment.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Aging Clin Exp Res. 2020 Jan 2. Epub 2020 Jan 2. PMID: 31898168

Article Published Date : Jan 01, 2020

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Sitting Sickness

Additional Keywords : Risk Factors

[+]

The Boswellia serrate and lemon balm tablet in older adults can be beneficial on improvement of memory.Mar 31, 2018

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Pubmed Data : Arch Gerontol Geriatr. 2018 Mar - Apr;75:146-150. Epub 2017 Dec 28. PMID: 29306113

Article Published Date : Mar 31, 2018

Study Type : Human Study

Additional Links

Substances : Frankincense, Lemon Balm

Diseases : Cognitive Decline/Dysfunction, Memory Disorders

Pharmacological Actions : Neuroprotective Agents

[+]

The current study demonstrates the potential of magnesium-L-threonate for treating cognitive impairment in older adults.Oct 26, 2015

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[+]

The results of this study indicate that working in an occupation with high or medium-high magnetic field exposure may increase the risk of severe cognitive dysfunction.Apr 16, 2014

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Pubmed Data : Am J Epidemiol. 2017 Jul 13. Epub 2017 Jul 13. PMID: 28992036

Article Published Date : Jul 12, 2017

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Sitting Sickness

[+]

These results indicate that working near a 1.5 Tesla MRI system may elicit neurobehavioral effects. Oct 01, 2003

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Pubmed Data : Magn Reson Med. 2003 Oct ;50(4):670-4. PMID: 14523950

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Pubmed Data : Nutrients. 2018 Sep 20 ;10(10). Epub 2018 Sep 20. PMID: 30241302

Article Published Date : Sep 19, 2018

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

This cohort study demonstrates a potential adverse effect of microwave radiofrequency electromagnetic fields on cognitive function that involve brain regions mostly exposed during mobile phone use.Jan 01, 2018

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Pubmed Data : Eur J Nutr. 2019 Jun 21. Epub 2019 Jun 21. PMID: 31227861

Article Published Date : Jun 20, 2019

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Pubmed Data : Wei Sheng Yan Jiu. 2000 Mar 30 ;29(2):102-3. PMID: 12725088

Article Published Date : Mar 30, 2000

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction

Additional Keywords : EMF

Anti Therapeutic Actions : Electromagnetic Fields, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation

Problem Substances : Cell Phone Exposure

[+]

Using a phone more than 2 hours a day is associated with sleep deprivaiton and day sleepiness in medical students.Jan 01, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Neuron. 2010 Jan 28 ;65(2):165-77. PMID: 20152124

Article Published Date : Jan 27, 2010

Study Type : Animal Study

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Substances : Magnesium

Diseases : Cognitive Decline/Dysfunction, Learning disorders

Pharmacological Actions : Neuroprotective Agents

[+]

"Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy."Feb 14, 2012

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Pubmed Data : Clin Cancer Res. 2012 Feb 14. Epub 2012 Feb 14. PMID: 22338017

Article Published Date : Feb 14, 2012

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Pubmed Data : Biochimie. 2016 Aug 26. Epub 2016 Aug 26. PMID: 27569259

Article Published Date : Aug 25, 2016

Study Type : Animal Study

Additional Links

Substances : Omega-3 Fatty Acids, Vitamin B-12

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

A diet containing a mixture of P. montana and red ginseng extracts reversed learning and memory impairments.Jul 31, 2018

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Pubmed Data : Food Sci Biotechnol. 2018 Aug ;27(4):1193-1200. Epub 2018 Apr 4. PMID: 30263850

Administration of THC was observed to enhance the neurogenesis in the brainSep 20, 2017

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Pubmed Data : Neurotox Res. 2017 Sep 21. Epub 2017 Sep 21. PMID: 28933048

Article Published Date : Sep 20, 2017

Study Type : Animal Study

Additional Links

Substances : Delta-tetrahydrocannabinol (THC)

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neurogenesis

[+]

Aged garlic ethyl acetate extract may therefore be a beneficial food for protecting against neurodegeneration such as Alzheimer's disease.May 31, 2019

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Pubmed Data : Prev Nutr Food Sci. 2019 Jun ;24(2):165-170. Epub 2019 Jun 30. PMID: 31328121

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Pubmed Data : Eur J Pharmacol. 2016 Apr 15 ;777:60-9. Epub 2016 Feb 27. PMID: 26927754

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Pubmed Data : Sci Rep. 2017 Oct 18 ;7(1):13510. Epub 2017 Oct 18. PMID: 29044140

Article Published Date : Oct 17, 2017

Study Type : Animal Study

Additional Links

Substances : Bifidobacterium Breve

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Bacopa enhances cognitive function and protects against neurodegeneration in an Alzheimer's disease model. Oct 04, 2009

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Pubmed Data : J Ethnopharmacol. 2009 Oct 4. Epub 2009 Oct 4. PMID: 19808086

Article Published Date : Oct 04, 2009

Study Type : Animal Study

Additional Links

Substances : Bacopa

Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction, Neurodegenerative Diseases

[+]

Additional Keywords : Plant Extracts

[+]

Behavioural domains and the gut microbiome are both impacted by diet and exercise but in unrelated ways.Dec 31, 2013

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Pubmed Data : Turk J Med Sci. 2015 ;45(5):1127-36. PMID: 26738358

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Pubmed Data : Nutrients. 2019 Mar 29 ;11(4). Epub 2019 Mar 29. PMID: 30934852

Article Published Date : Mar 29, 2019

Study Type : Animal Study

Additional Links

Substances : Gamma-Oryzanol

Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Chronic curcumin ameliorates AD-related cognitive deficits and that upregulated BDNF-ERK signaling in the hippocampus.Dec 31, 2014

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Pubmed Data : Pharmacol Biochem Behav. 2015 Jul ;134:22-30. Epub 2015 Apr 28. PMID: 25931267

Article Published Date : Jun 30, 2015

Study Type : Animal Study

Additional Links

Substances : Chrysin

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Citrulline supplementation may be a promising preventive nutritional approach to limit age-related cognitive decline.Dec 26, 2019

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Pubmed Data : Sci Rep. 2019 Dec 27 ;9(1):20138. Epub 2019 Dec 27. PMID: 31882891

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Pubmed Data : Mol Med Rep. 2018 Sep ;18(3):3437-3444. Epub 2018 Jul 24. PMID: 30066867

Article Published Date : Aug 31, 2018

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Cognitive Decline/Dysfunction, Pancreatitis

Pharmacological Actions : Neuroprotective Agents

[+]

Combined pretreatment with the extract of Nardosatchys jatamansi, crocetin and selenium led to improved behavioural outcomes.Sep 30, 2012

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Pubmed Data : Neurol Sci. 2012 Oct ;33(5):1011-20. Epub 2011 Dec 15. PMID: 22170092

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Pubmed Data : Synapse. 2017 Mar ;71(3). Epub 2017 Jan 12. PMID: 27997735

Article Published Date : Feb 28, 2017

Study Type : Animal Study

Additional Links

Substances : Curcuma Longa

Diseases : Aging: Brain , Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

[+]

Curcumin enhances neurogenesis and cognition in aged rats.Jan 01, 2012

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Pubmed Data : PLoS One. 2012 ;7(2):e31211. Epub 2012 Feb 16. PMID: 22359574

Article Published Date : Jan 01, 2012

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Aging: Brain , Cognitive Decline/Dysfunction

Pharmacological Actions : Neuritogenic

[+]

Curcumin has a neuroprotective effect against homocysteine-induced cognitive impairment and oxidative stress in the rat.Oct 01, 2010

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Pubmed Data : Pharmacol Biochem Behav. 2010 Oct;96(4):378-85. Epub 2010 Jul 6. PMID: 20619287

Article Published Date : Oct 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Neurodegenerative Diseases, Oxidative Stress

Pharmacological Actions : Antioxidants, Neuroprotective Agents

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View the Evidence: 583 Abstracts with Cognitive Decline/Dysfunction Research

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Bacopa monnieri has the potential to improve cognition.Dec 31, 2013

Children who live in a fluorosis area have 5 times higher odds of developing low IQ than those who live in a nonfluorosis area or a slight fluorosis area.Jan 01, 2008

Exposure to high levels of fluoride may adversely influence children's intelligence development.Dec 01, 2008

Higher coffee consumption is associated with reduced risk for Alzheimer disease.May 31, 2016

Increased consumption of fruit and vegetables is associated with a reduced risk of cognitive impairment and dementia.Dec 31, 2016

Meta-analytic findings suggested overall benefits of EGb 761 for stabilizing or slowing decline in cognition of subjects with cognitive impairment and dementia.Dec 31, 2014

People with various levels of cognitive impairment can benefit from supervised multi-modal exercise.Dec 26, 2017

Rates of autism, speech disorders, mental retardation, infantile spasms, and thinking abnormalities were higher in children exposured to higher thimerosal levels.Aug 01, 2006

Tamoxifen interferes with cognitive function in breast cancer patients. Nov 01, 2000

This meta-analysis found a statistically significant increase in the risk of dementia among patients with rheumatoid arthritis.Dec 31, 2015

This meta-analysis suggests that physical activity interventions positively influence cognitive function in patients with dementia.Dec 31, 2015

This study suggests that meditation and mind-body exercises are effective to improve cognition of older adults aged 60 years or above.Feb 22, 2019

"Effects of prior light exposure on early evening performance, subjective sleepiness, and hormonal secretion."Feb 01, 2012

A 5-min bout of walking at a self-selected intensity is associated with improved cognitive function.Jan 04, 2018

A closer adherence to the Mediterranean diet was associated with a better cognitive status.Apr 04, 2018

A high intake of nuts may protect older adults from cognitive decline.Nov 21, 2019

A higher consumption of green tea is associated with a lower prevalence of cognitive impairment in humans.Feb 01, 2006

A lack of attention and concentration may occur in subjects who talk on mobile phones for longer times, compared to those who use phones relatively less.Sep 30, 2017

A Mediterranean diet supplemented with olive oil or nuts is associated with improved cognitive function in older populations. Jun 30, 2015

A moderate intake of EPA and DHA may postpone cognitive decline in elderly men. Apr 01, 2007

A polyphenol-rich extract from grape and blueberry improves age-related episodic memory decline in individuals with the highest cognitive impairments.Jul 18, 2018

A robust association was found between low omega-3 levels and cognitive impairment in an elderly population. Oct 04, 2016

A sedentary lifestyle could be a potential risk factor for mild cognitive impairment or subsequent dementia.Apr 24, 2018

A simple meditation or music listening program may improve stress, mood, well-being, sleep, and QOL in adults with subjective cognitive decline.Apr 07, 2016

Acupuncture at Tiaoshen Yizhi acupoints can be used to improve cognitive function in patients with mild cognitive impairment.Jan 31, 2017

Acute low-level exposure to microwaves modulated at 7 Hz can affect cognitive processes such as attention and short-term memory in humans.Oct 01, 2002

Adherence to Mediterranean diet and subsequent cognitive decline in men with cardiovascular disease.Jan 21, 2020

Adverse oral health and cognitive decline: the health, aging and body composition study.Jan 31, 2013

Aerobic fitness may have a positive influence on protection of brain even in aMCI CSF biomarker, a high-risk population to convert to AD.May 31, 2016

Almond consumption leads to an improvement in cognitive function in overweight and obese patients. Jan 31, 2017

Anticholinergic burden and risk of cognitive impairment in elderly nursing home residents with depression.May 27, 2019

Art therapy is associated with sustained improvement in cognitive function in the elderly with mild neurocognitive disorder.Nov 08, 2018

Ashwagandha may be effective in enhancing both immediate and general memory in people with mild cognitive impairment.Nov 01, 2017

Assessment of cognitive impairment and its correlation with vitamin D levels patients on maintenance hemodialysis.Feb 29, 2020

Association of vitamin D and vitamin B12 with cognitive impairment in elderly aged 80 years or older.Feb 27, 2019

Astaxanthin-rich Haematococcus pluvialis extract improves cognitive function in the healthy aged individuals.Aug 31, 2012

B vitamins appear to slow cognitive and clinical decline in people with mild cognitive impairment, in particular in those with elevated homocysteine.Jul 21, 2011

Bacopa enhances cognitive performance in the aging.Jul 01, 2008

Being physically active during early adulthood and midlife contributes to prevention of poor subjective cognitive function in late-life.Nov 16, 2017

Bergamot polyphenolic fraction administration may be proposed as a potential supplementation strategy to improve cognitive outcome in schizophrenia.Jul 31, 2017

Black tea consumption was association with better cognitive performance among the elderly aged 60 years and above in China.Dec 31, 2014

Blueberry supplementation led to enhanced neural activation in mild cognitive impairment. Feb 20, 2017

Breath Qigong improves recognition in seniors With vascular cognitive impairment.Dec 31, 2018

Caffeine intake was related to moderately better cognitive maintenance over 5 years in older women with vascular disorders.Dec 31, 2012

Chocolate intake is associated with better cognitive function.Apr 30, 2016

Chocolate intake was associated with a lower risk of cognitive decline.May 05, 2016

Chronic daily consumption of flavanone-rich 100% orange juice over 8 week was beneficial for cognitive function in healthy older adults.Feb 28, 2015

Chronic hyperglycemia in people with diabetes may disrupt the brain’s topological integration, and lead to mental slowing and cognitive impairment.Dec 31, 2015

Circulating levels of autophagy markers were low in children with higher fluoride body burden and lower intelligence quotient scores.Aug 31, 2019

Circulating vitamin D levels and Alzheimer's disease.Dec 01, 2019

Cognitive deterioration among bipolar disorder patients infected by Toxoplasma gondii is correlated to interleukin 6 levels.Jun 30, 2015

Continuous intake of chlorogenic acids appears to improve attention and executive function among cognitive functions in mild cognitive impairment.Oct 28, 2019

Cycling in appears to improve some aspects of cognitive function and mental health.Dec 31, 2018

Dance therapy improves cognitive functioning, quality of life and psychological well-being in elderly persons.Jan 01, 2010

Dangshen (Codonopsis pilosula) and Bai guo (Gingko biloba) enhance learning and memory. Jul 01, 2004

Decreased sunlight exposure is associated with an increased probability of cognitive impairment among depressed individuals. Aug 01, 2009

Delayed manifestation of cognitive dysfunction post-HPV vaccination.Jun 30, 2015

Dewaxed brown rice has the potential to be a useful staple food that maintains brain homeostasis among elderly individuals.Dec 31, 2018

Dietary intake of riboflavin and unsaturated fatty acid can improve the multi-domain cognitive function in middle-aged and elderly populations.Dec 31, 2018

Dietary niacin may protect against Alzheimer's disease and age related cognitive decline.Jul 31, 2004

Dietary supplementation with blueberries improves cognition among older adults.Mar 09, 2017

Effects of 12-week avocado consumption on cognitive function among adults with overweight and obesity.Jan 31, 2020

Electrohypersensitive persons in this study were suffering not only from their symptoms, but also from economical and social problems.Apr 01, 2012

Electrophysiological assessment of the impact of mobile phone radiation on cognition in persons with epilepsy.Feb 28, 2019

EMF modulates the responses of EEG oscillatory activity during cognitive processes.Dec 01, 2000

Excessive sugar consumption among older adults showed a notable association with poor cognitive functions.Dec 31, 2018

Exercise capacity is strongly associated with cognitive function.Jan 31, 2017

Exposure a 900 MHz electromagnetic field results in reduced performance in sleep-dependent motor-sequence tasks in healthy subjects compared to controls.Sep 01, 2013

Exposure to a continuous TETRA-like signal may lead to fatigue and trouble concentrating.May 01, 2011

Exposure to ambient air pollution and cognitive impairment in community-dwelling older adults: the Korean frailty and aging cohort studyJan 06, 2019

Exposure to cytomegalovirus, herpes simplex virus type 2, or toxoplasma gondii was associated with cognitive deterioration in older individuals.Dec 23, 2015

Exposure to radiation from a mobile phone base is associated with lack of appetite, lack of concentration, irritability, and trouble sleeping.Dec 30, 2013

Cognitive Decline/Dysfunction

View the Evidence:
583 Abstracts with Cognitive Decline/Dysfunction Research