Colon Cancer

Name	AC	CK
Curcumin	64	87
Vitamin D	13	46
Coffee	3	31
Nuts	3	31
Apples	8	30
Sulforaphane	13	27
Flavonoids	18	22
Fiber	9	21
Resveratrol	16	20
Polyphenols	13	17
Vitamin C	12	17
Black Currant	3	16
Fermented Foods and Beverages	11	15
Garlic	5	15
Pterostilbene	10	15
Berberine	9	13
Blueberry	7	13
Ginger	7	13
Probiotics	8	13
Anthocyanins	9	12
Cryptoxanthin	2	12
Folic Acid	2	12
Lutein	2	12
Magnesium	2	12
Prebiotics	3	12
Silibinin	6	12
Vegetables: All	2	12
Antineoplastons	2	11
Banana	2	11
Ellagic Acid	7	11
Lactoferrin	2	11
Lettuce	2	11
Soy	6	11
Fruit: All	1	10
Genistein	7	10
Ginsenosides	9	10
Lichens	6	10
Psyllium	1	10
Blackberry	5	9
Cranberry	4	9
Fucoidan	8	9
Omega-3 Fatty Acids	5	9
Thymoquinone	6	9
Walnut	6	9
Astaxanthin	5	8
Chaga Mushroom (Inonotus obliquus)	7	8
Flaxseed	5	8
Grape	6	8
Rutin	6	8
Shikonin	5	8
Adlay	5	7
Lignans	5	7
Limonoids	2	7
Mushrooms: All	3	7
Myricetin	6	7
Nigella sativa (aka Black Seed)	4	7
Raspberry	3	7
Wogonin	2	7
Asiatic Acid	5	6
Caffeic Acid	4	6
Calcium	3	6
Cannabinoids	4	6
EGCG (Epigallocatechin gallate)	4	6
Ginseng	4	6
Isoflavones	4	6
Lingonberry	2	6
Luteolin	5	6
Mustard: Field/Turnip	2	6
Nobiletin	4	6
Olive	5	6
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)	2	5
Beta-glucan	3	5
Cannabidiol	3	5
Curry Leaves	3	5
Deguelin	3	5
Fucoxanthin	3	5
Honey	5	5
Indian Gooseberry	1	5
Lactobacillus probiotics	1	5
Oyster Mushroom	4	5
Quercetin	3	5
Rosemary	4	5
Selenium	3	5
Shiitake Mushroom	3	5
Wheat Grass	4	5
White Mulberry	1	5
Apple Pectin	2	4
Beans: All	2	4
Bee Propolis	4	4
Cannabis	2	4
Capsaicin	2	4
Carnosic Acid	3	4
Catechin	3	4
Cucurbitacin E	3	4
Fisetin	4	4
Ginseng (Korean)	3	4
Grape Seed Extract	3	4
Green Tea	2	4
Guar gum	2	4
Lactobacillus casei	2	4
Lactobacillus rhamnosus	2	4
Maitake Mushroom	2	4
Miso	2	4
Modified Citrus Pectin	2	4
Oats	3	4
Olive Oil	3	4
Phloretin	4	4
Pomegranate	3	4
Sage	3	4
Spinach	2	4
Ursolic Acid	4	4
Vitamin A	2	4
Vitamin E: Gamma-Tocopherol	2	4
Wheat Bran	3	4
Whey	3	4
Xanthohumol	4	4
6-Shogaol	3	3
Acai	2	3
Antineoplaston A3	1	3
Apigenin	3	3
Apple Polyphenols	3	3
Arctigenin	3	3
Ashwagandha	2	3
Bacopa	2	3
Baicalein	2	3
Brown Rice	2	3
Butyrate	3	3
Carotenoids	2	3
Carrot	3	3
Chokeberry	3	3
Cucurbitacin B	2	3
Curcuma Purpurascens	2	3
Cyanidin 3-glucoside	3	3
Frankincense	2	3
Gallic Acid	2	3
Garlic: Aged	2	3
Genipin	3	3
Ginseng (American)	2	3
Guava	2	3
Hydroxytyrosol	3	3
Inositol Hexaphosphate	2	3
Lactobacillus Acidophilus	2	3
Lotus	3	3
Lychee	2	3
Mangiferin	2	3
Manuka Honey	3	3
Melatonin	3	3
Mistletoe	1	3
Neem	2	3
Nexrutine (Phellodendrom)	2	3
Olive leaf extract	2	3
P-Coumaric Acid	3	3
Piperine	3	3
Piperlongumine	2	3
Prunella vulgaris	3	3
Puerarin	2	3
Rice	2	3
Saccharomyces Boulardii	2	3
Sesamol	2	3
Sweet Potato	3	3
Sweet Potato: Purple	3	3
Tart Cherry	2	3
Urolithin A	2	3
Vitamin E	2	3
Vitamin E: Gamma-tocotrienol	3	3
Wheat: Fermented	3	3
White Tea	2	3
Achiote	1	2
Aleurone	2	2
Allicin	2	2
Andrographis	2	2
Antrodia camphorata	2	2
Apple	2	2
Arginine	1	2
Avenanthramides	2	2
Barley	1	2
Bee Venom	1	2
Berries: All	2	2
Bifidobacterium	1	2
Bifidobacterium Longum	1	2
Black Pepper	1	2
Black Raspberry	2	2
Black Tea	1	2
Broccoli Sprouts	2	2
Bromelain	1	2
Buckwheat	1	2
Caffeine	1	2
Camel Milk	2	2
Cannabigerol	1	2
Capparis spinosa (caper)	2	2
Caraway	1	2
Caraway Oil	1	2
Carnosol	2	2
Chickpea	1	2
Chlorophyll	1	2
Chrysin	1	2
Citrus aurantium	2	2
Cloudberry	1	2
Coconut	1	2
Common bean	1	2
Coriandrum sativum	1	2
Cumin	1	2
D-Limonene	2	2
DHA (Docosahexaenoic Acid)	2	2
Daidzein	2	2
Dandelion	1	2
Emodin	2	2
Estrone	1	2
Eucalyptus	1	2
Evodiamine	1	2
Flaxseed Oil	1	2
Gac	1	2
Garcinia indica	1	2
Ginkgo biloba	1	2
Gotu Kola	1	2
Grains: All	1	2
Grapefruit	1	2
Hesperidin	1	2
Jambul	1	2
Kefir	2	2
Lactobacillus Brevis	1	2
Lentils	1	2
Lentinan	1	2
Lion's Mane (Hericium Erinaceus)	1	2
Medicinal Mushrooms	2	2
Methionine	1	2
Mustard Greens	1	2
Mustard Seeds	1	2
Nutmeg	1	2
Oak	1	2
Oleuropein	2	2
Oolong tea	1	2
Orange	1	2
Orange: Mandarin	1	2
Palm Oil	1	2
Pectin	1	2
Persimmon	1	2
Phellinus Linteus	2	2
Potato	2	2
Potato: Pigmented	1	2
Propolis: Brazillian	1	2
Pumpkin Seed Oil/Meal	1	2
Pumpkin Seeds	2	2
Red Wine	1	2
Reishi Mushroom	1	2
Rhubarb	2	2
Rose	2	2
Rose Hips	2	2
Rosemaric Acid	1	2
Rosmarinic acid	1	2
Rye	1	2
Solanum Glaucophyllum	1	2
Soy Protein	1	2
Spirulina	2	2
Sprouts	1	2
Stearic Acid (stearate)	1	2
Strawberry	2	2
Tannic Acid	2	2
Tanshinone IIA	2	2
Tetrahydrocurcumin	1	2
Theaflavins	2	2
Tomato	2	2
Tricin	1	2
Turmeric	2	2
Vitamin B-12	1	2
Vitamin D3	1	2
Vitamin E: delta-tocopherol	1	2
Vitamin K2	1	2
Water	1	2
Water: Deuterium Depleted	2	2
Watermelon	1	2
Yoghurt	1	2
Aloe Vera	1	1
Amygdalin	1	1
Anandamide	1	1
Angelica	1	1
Apricot Kernel	1	1
Arabinoxylans	1	1
Arnica	1	1
Artesunate	1	1
Asparagus	1	1
Avocado	1	1
Bacillus coagulans	1	1
Bael	1	1
Bai Zhu	1	1
Bamboo	1	1
Banaba	1	1
Beet	1	1
Benzyl isothiocyanate	1	1
Berbamine	1	1
Bergamot orange	1	1
Beta Sitosterol	1	1
Betulinic acid	1	1
Bifidobacterium Bifidum	1	1
Bilberry	1	1
Bitter Melon	1	1
Black Bean	1	1
Bran	1	1
Burdock	1	1
CLA (Conjugated Linoleic Acid)	1	1
Cannabinoids: Synthetic	1	1
Carob	1	1
Chamomile	1	1
Cherry: All Varieties	1	1
Chitosan	1	1
Chlorogenic Acid	1	1
Cinnamon	1	1
Clove	1	1
Corn Silk	1	1
Coumestrol	1	1
Curcuma phaeocaulis	1	1
Daikon radish	1	1
EPA (Eicosapentaenoic Acid)	1	1
Echinacea	1	1
Egg	1	1
Endive (Cichorium endivia. L )	1	1
Enterodiol	1	1
Enterolactone	1	1
Eugenol	1	1
Euphorbia cotinifolia	1	1
Fenugreek	1	1
Ferulic acid	1	1
Fish Oil	1	1
Geraniol	1	1
Gingerol	1	1
Ginseng (Asian)	1	1
Ginseng (Siberian)	1	1
Glycitein	1	1
Goji	1	1
Gold	1	1
Gold (nanoparticles)	1	1
Grapes	1	1
Graviola	1	1
Guduchi	1	1
Haematococcus pluvialis	1	1
Hazelnut	1	1
Homeopathic Medicine: All	1	1
Honokiol	1	1
Horse Chestnut	1	1
Infection/Infectitious Agent Byproducts (Beneficial)	1	1
Isothiocyanates	1	1
Kanuka Honey	1	1
Kimchi	1	1
Lactobacillus fermentum	1	1
Lactobacillus paracasei	1	1
Lactobacillus plantarum	1	1
Lactobacillus rhamnosus GG	1	1
Lauric acid	1	1
Legumes	1	1
Lime: Key	1	1
Lycopene	1	1
MSM (Methylsulfonylmethane)	1	1
Mastic gum	1	1
Melissa (Lemonbalm)	1	1
Milk Thistle	1	1
Molasses	1	1
Moringa oleifera	1	1
Myrica rubra	1	1
Naringenin	1	1
Nettle	1	1
Oleocanthal	1	1
Onion	1	1
Oregano	1	1
Oyster Mushroom: Indian	1	1
Palmitoylethanolamide	1	1
Parthenolide	1	1
Peach	1	1
Peanut	1	1
Pear	1	1
Peppermint	1	1
Phyllanthus emblica	1	1
Phytosterols	1	1
Piceatannol	1	1
Pine Cone	1	1
Piperidines	1	1
Plum	1	1
Polyunsaturated Fatty Acids (PUFAs)	1	1
Pomegranate flower	1	1
Prickly Pear Cactus	1	1
Pumpkin	1	1
Purple Carrots	1	1
Purslane	1	1
Radish	1	1
Raisins	1	1
Red Yeast Rice	1	1
Rice Bran	1	1
Rice: Black	1	1
Royal Jelly	1	1
Ruta Graveolens	1	1
Saffron	1	1
Salvia divinorum	1	1
Sea buckthorn	1	1
Sesame Seeds	1	1
Silymarin	1	1
Solasodine glycoalkaloids	1	1
Sorghum	1	1
Spearmint	1	1
St. Johns Wort	1	1
Stevia	1	1
Stilbenes	1	1
Sweet Cherry	1	1
Tangeretin	1	1
Thistle	1	1
Thyme	1	1
Toad	1	1
Tocotrienol: Gamma	1	1
Trichosanthes Kirilowii	1	1
Triphala	1	1
Tyrosol	1	1
Ume (Japanese apricot)	1	1
Vitamin K	1	1
Vitex Agnus	1	1
Wasabi	1	1
Willow Bark	1	1
Zerumbone	1	1
pistachios	1	1

Name	AC	CK
Sugar Sweetened Beverages	2	12
Foods: High Glycemic Load	1	10
Meat	1	10
Casein	2	4
Sucrose	2	4
Benzo(a)pyrene	1	2
Bisphenol A	2	2
Chlorinated Water	1	2
Ferrous Fumarate	1	2
Fructose	1	2
Glucose	1	2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	2
Sodium lauryl sulfate	1	2
2,4-Dichlorophenoxyacetic acid	1	1
Adrenaline	1	1
Aromatase Inhibitor Drugs	1	1
Artificial Sweeteners	1	1
Aspartame	1	1
Atorvastatin	1	1
Bisphosphonates	1	1
Doxorubicin	1	1
Saccharin	1	1
Sodium Cyclamate	1	1

Name	AC	CK
Sunlight exposure	3	23
Light-Emitting Diodes (LEDs) Therapy	2	3
Dietary Modification: Low Carbohydrate/Ketogenic	1	2
Exercise	1	2
Light Therapy	1	2
Thermal Therapy: Far-Infrared	1	2
Heat Therapy	1	1
Microbiota Transfer Therapy	1	1

Name	AC	CK
Western Diet	7	14
Gamma Irradiation: "Cold Pasteurization"	1	2
Microwave Cooking	1	1
Stress	1	1

[+]

Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

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Pubmed Data : Clin Cancer Res. 2015 Oct 1 ;21(19):4398-409. Epub 2015 May 28. PMID: 26023082

Article Published Date : Sep 30, 2015

Study Type : Animal Study, Human Study, In Vitro Study

Additional Links

Substances : Cryptoxanthin

Diseases : Colon Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Chemotherapeutic Synergy: Oxaliplatin

[+]

Coffee consumption was associated with 26% lower odds of developing colorectal cancer.Mar 31, 2016

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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2016 Apr ;25(4):634-9. PMID: 27196095

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Pubmed Data : J Natl Cancer Inst. 2012 Nov 21 ;104(22):1702-11. Epub 2012 Nov 7. PMID: 23136358

Article Published Date : Nov 20, 2012

Study Type : Human Study

Additional Links

Diseases : Colon Cancer, Colon Cancer: Prevention

Pharmacological Actions : Carcinogens

Problem Substances : Foods: High Glycemic Load

[+]

Individuals consuming the highest intakes of dietary fiber have reduced risks of incident colorectal adenoma and distal colon cancer.Aug 11, 2015

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Pubmed Data : Am J Clin Nutr. 2015 Aug 12. Epub 2015 Aug 12. PMID: 26269366

Article Published Date : Aug 11, 2015

Study Type : Human Study

Additional Links

Substances : Fiber

Diseases : Colon Cancer, Colon Cancer: Prevention, Colorectal Cancer, Colorectal Cancer: Prevention

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

Additional Keywords : Risk Reduction

[+]

Myofascial pain as assessed by tender trigger points and 25(OH)D deficiency showed a significant association with cancer.Jul 05, 2017

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Pubmed Data : J Am Coll Nutr. 2017 Jul 6:1-7. Epub 2017 Jul 6. PMID: 28682182

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Pubmed Data : Rev Environ Health. 2009 Jan-Mar;24(1):59-74. PMID: 19476292

Article Published Date : Jan 01, 2009

Study Type : Human Study

Additional Links

Substances : Apples

Diseases : Colon Cancer, Colorectal Cancer

[+]

[+]

verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells. Aug 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Genom Data. 2015 Sep 1 ;5:189-191. PMID: 26309812

Article Published Date : Aug 31, 2015

Study Type : Human In Vitro

Additional Links

Substances : Mushrooms: All

Diseases : Colon Cancer

Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemotherapeutic

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Epigenetic Modification In Cancer, Gene Expression Regulation

[+]

Wogonin decreased the expression of glycolysis-related proteins, glucose uptake and lactate generation in a dose-dependent manner.Jan 31, 2014

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Pubmed Data : Mol Carcinog. 2014 Feb ;53 Suppl 1:E107-18. Epub 2013 Jun 13. PMID: 23761018

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Pubmed Data : Surg Case Rep. 2017 Dec ;3(1):65. Epub 2017 May 10. PMID: 28488173

Article Published Date : Nov 30, 2017

Study Type : Human: Case Report

Additional Links

Diseases : Colon Cancer

Additional Keywords : Spontaneous Regression

[+]

This is the first report showing complete regression of a colon adenoma after intratumoural injection with Viscum album extract.Nov 30, 2014

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Pubmed Data : J Gastrointestin Liver Dis. 2014 Dec ;23(4):449-52. PMID: 25532007

Pubmed Data : Cancer Lett. 2019 Feb 1 ;448:20-30. Epub 2019 Feb 1. PMID: 30716361

Article Published Date : Jan 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Diseases : Colon Cancer

Pharmacological Actions : Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors

[+]

A combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.Jan 01, 2010

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Pubmed Data : Food Chem Toxicol. 2010 Jan;48(1):390-5. Epub 2009 Oct 25. PMID: 19861145

Article Publish Status : This is a free article. Click here to read the complete article.

Annatto has possible chemopreventive effects through modulation of the cryptal cell proliferation but not at the initiation stage of colon carcinogenesis.Apr 03, 2005

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Pubmed Data : Mutat Res. 2005 Apr 4 ;582(1-2):146-54. PMID: 15781219

Article Published Date : Apr 03, 2005

Study Type : Animal Study

Additional Links

Substances : Achiote

Diseases : Colon Cancer, DNA damage

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

Additional Keywords : Plant Extracts

[+]

Anthocyanin containing purple fleshed potatoes suppressed colon tumorigenesis via elimination of colon cancer stem cells.Aug 13, 2015

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Pubmed Data : J Nutr Biochem. 2015 Aug 14. Epub 2015 Aug 14. PMID: 26383537

Pubmed Data : Carcinogenesis. 2000 Aug;21(8):1461-7. PMID: 20652274

As mono-therapy the natural isoflavone genistein has a powerful therapeutic effect in vivo on A431 and Colo205 tumors.Apr 06, 2016

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Pubmed Data : Int J Oncol. 2015 Nov ;47(5):1749-58. Epub 2015 Sep 18. PMID: 26398706

Article Published Date : Oct 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Microbiota

[+]

Bee venom could be applicable as an anti-colon cancer agent.Oct 29, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Mol Cancer Ther. 2016 Jul 25. Epub 2016 Jul 25. PMID: 27458137

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Pubmed Data : Carcinogenesis. 2014 Dec ;35(12):2787-97. Epub 2014 Sep 30. PMID: 25269802

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Pubmed Data : PLoS One. 2015 ;10(7):e0132435. Epub 2015 Jul 17. PMID: 26186212

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Diseases : Clostridium Infections, Colon Cancer

Additional Keywords : Chromosomal Aberration, Microbiota

Problem Substances : Chlorinated Water

[+]

Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death.Aug 13, 2015

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Pubmed Data : Cancer Prev Res (Phila). 2019 Dec 9. Epub 2019 Dec 9. PMID: 31818852

Article Published Date : Dec 08, 2019

Pubmed Data : Invest New Drugs. 1996;14(4):365-9. PMID: 9157071

Article Published Date : Jan 01, 1996

Study Type : Animal Study

Additional Links

Substances : Curry Leaves, Mustard Greens

Diseases : Colon Cancer

[+]

Deguelin might be a potential therapeutic agent for treatment of colorectal cancer.Oct 31, 2012

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Pubmed Data : Dig Dis Sci. 2012 Nov ;57(11):2873-82. Epub 2012 May 24. PMID: 22623043

Article Published Date : Oct 31, 2012

Study Type : Animal Study

Additional Links

Substances : Deguelin

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Interleukin-8 downregulation, NF-kappaB Inhibitor

[+]

Delta and gamma tocopherols inhibit colon carcinogenesis.Mar 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Oncotarget. 2016 May 6. Epub 2016 May 6. PMID: 27167203

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Pubmed Data : J Ethnopharmacol. 2015 Sep 15 ;173:303-12. Epub 2015 Jul 22. PMID: 26210065

Article Published Date : Sep 14, 2015

Study Type : Animal Study

Additional Links

Substances : Chaga Mushroom (Inonotus obliquus)

Diseases : Colon Cancer, Colon Cancer: Prevention

Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive

[+]

Eriodictyol can be used as an effective chemopreventive agent against DMH-induced colon carcinogenesis.Aug 31, 2017

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Pubmed Data : Toxicol Res (Camb). 2017 Sep 1 ;6(5):678-692. Epub 2017 Jun 19. PMID: 30090535

Article Published Date : Aug 31, 2017

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

[+]

Extracts of Neem leaf were effective in inducing apoptosis in leukemia and colon cancer cells.Oct 31, 2015

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Pubmed Data : J Pharm Pharm Sci. 2015 Nov ;18(4):729-46. PMID: 26626256

Article Published Date : Oct 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Neem

Diseases : Acute T cell Leukemias, Colon Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Plant Extracts, Selective Cytotoxicity

[+]

Extravirgin olive oil up-regulates CB₁ tumor suppressor gene in human colon cancer cells.Feb 28, 2015

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Pubmed Data : J Nutr Biochem. 2015 Mar ;26(3):250-8. Epub 2014 Dec 3. PMID: 25533906

Gamma and delta tocopherols supplementation at 0.2% in diet significantly inhibited PhIP-induced and colitis-promoted colon carcinogenesis.Dec 31, 2016

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Pubmed Data : Environ Toxicol Pharmacol. 2015 Nov ;40(3):870-5. Epub 2015 Sep 28. PMID: 26492449

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Pubmed Data : PeerJ. 2015 ;3:e859. Epub 2015 Apr 7. PMID: 25870767

Article Published Date : Dec 31, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Water

Diseases : Colon Cancer

Pharmacological Actions : Apoptotic

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

[+]

High-fat Western diet-induced obesity contributes to increased tumor growth in mouse models of human colon cancer.Nov 30, 2016

Pubmed Data : J Pharmacol Sci. 2018 Aug ;137(4):324-332. Epub 2018 May 5. PMID: 30150145

Article Published Date : Jul 31, 2018

Study Type : Animal Study

Additional Links

Substances : Glycyrrhiza uralensis

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Gastrointestinal Agents

Additional Keywords : Phytotherapy, Polysaccharides

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Basic Clin Pharmacol Toxicol. 2008 Jul ;103(1):48-54. Epub 2008 Jul 1. PMID: 18484961

Article Published Date : Jun 30, 2008

Study Type : Animal Study

Additional Links

Substances : Licorice

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antineoplastic Agents, Antioxidants, Antiproliferative , Chemoprotective Agents

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Limonin might be a candidate chemopreventive agent against intestinal carcinogenesis.Jun 30, 2015

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Pubmed Data : J Clin Biochem Nutr. 2015 Jul ;57(1):39-43. Epub 2015 Jun 17. PMID: 26236099

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Pubmed Data : Hum Exp Toxicol. 2014 Nov ;33(11):1176-85. Epub 2014 Feb 14. PMID: 24532706

Article Published Date : Oct 31, 2014

Study Type : Animal Study

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Substances : Luteolin

Diseases : Colon Cancer

Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Chemotherapeutic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

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Magnesium improves cisplatin-mediated tumor killing while protecting against cisplatin-induced nephrotoxicity.Jul 31, 2017

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Pubmed Data : Am J Physiol Renal Physiol. 2017 Aug 1 ;313(2):F339-F350. Epub 2017 Apr 19. PMID: 28424213

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Pubmed Data : J Nutr Biochem. 2017 Apr ;42:17-25. Epub 2017 Jan 11. PMID: 28107678

Article Published Date : Mar 31, 2017

Study Type : Animal Study

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Substances : Nobiletin

Diseases : Colitis, Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Chemopreventive, Heme oxygenase-1 inducer

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Nutmeg effectively inhibits cancer growth and metabolism by inhibiting the activity of lactate dehydrogenase (LDH).Dec 31, 2015

Oral administration of nobiletin significantly inhibited colitis-associated colon carcinogenesis in mice.Sep 09, 2015

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Pubmed Data : Mol Nutr Food Res. 2015 Sep 10. Epub 2015 Sep 10. PMID: 26445322

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Pubmed Data : PLoS One. 2017 ;12(2):e0170823. Epub 2017 Feb 17. PMID: 28212423

Article Published Date : Dec 31, 2016

Study Type : Animal Study, In Vitro Study

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Substances : Olive leaf extract

Diseases : Colon Cancer

Pharmacological Actions : Apoptotic

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Pomegranate seed oil suppresses chemically induced colon cancer in rats.Jun 01, 2004

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Pubmed Data : Cancer Sci. 2004 Jun;95(6):481-6. PMID: 15182427

Article Published Date : Jun 01, 2004

Study Type : Animal Study

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Substances : Pomegranate

Diseases : Colon Cancer

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Potential anticancer effect of red spinach extract.Dec 31, 2003

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Pubmed Data : Asia Pac J Clin Nutr. 2004 ;13(4):396-400. PMID: 15563447

Article Published Date : Dec 31, 2003

Study Type : Animal Study, In Vitro Study

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Substances : Spinach

Diseases : Breast Cancer, Colon Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Plant Extracts

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Pre- and postnatal exposure to dietary soy isoflavones suppresses the growth of colon tumors in male rats. Mar 01, 2009

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Pubmed Data : J Nutr. 2009 Mar;139(3):474-81. Epub 2009 Jan 13. PMID: 19141699

Article Published Date : Mar 01, 2009

Study Type : Animal Study

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Substances : Isoflavones, Soy

Diseases : Colon Cancer, Infant Nutrition, Prenatal Nutrition: Health of the Offspring

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Probiotic-derived poly P is expected to be an antitumor drug with fewer adverse effects than conventional drugs. Jan 31, 2016

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Pubmed Data : J Agric Food Chem. 2011 Feb 28. Epub 2011 Feb 28. PMID: 21355597

Article Published Date : Feb 28, 2011

Study Type : Animal Study

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Substances : Pterostilbene, Resveratrol

Diseases : Colon Cancer

Pharmacological Actions : Chemopreventive

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Pubmed Data : Arch Neurol. 2003 Feb;60(2):194-200. PMID: 15831530

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Pubmed Data : Pharmacol Res. 2018 Jul 18 ;135:49-59. Epub 2018 Jul 18. PMID: 30031170

Article Published Date : Jul 17, 2018

Study Type : Animal Study, In Vitro Study

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Substances : Wogonin

Diseases : Colon Cancer, Liver Cancer, Ovarian Cancer

Pharmacological Actions : Antiproliferative , Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Warburg Effect

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Sesamol suppresses cyclooxygenase-2 transcriptional activity in colon cancer cells.Feb 28, 2014

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Pubmed Data : J Leukoc Biol. 2015 Dec ;98(6):1015-25. Epub 2015 Aug 21. PMID: 26297795

Article Published Date : Nov 30, 2015

Study Type : Animal Study

Additional Links

Substances : Beta-glucan, Maitake Mushroom

Diseases : Colon Cancer

Pharmacological Actions : Immunomodulatory, Interleukin-12 upregulation

Additional Keywords : Natural Substance/Drug Synergy

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Soy and whey protein has anti-tumor activity in an animal model of colon cancer.Jan 11, 2005

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Pubmed Data : Mol Cancer. 2005 Jan 11;4(1):1. Epub 2005 Jan 11. PMID: 15644144

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Pubmed Data : Nutr Cancer. 2018 Oct 1:1-10. Epub 2018 Oct 1. PMID: 30273050

Article Published Date : Sep 30, 2018

Study Type : Animal Study

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View the Evidence: 845 Abstracts with Colon Cancer Research

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Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

Nut consumption was significantly associated with a reduced risk of cancer incidence.Jun 30, 2015

Review: there is a consistently strong inverse correlations with solar UVB for 15 types of cancers.Jan 01, 2012

A blackcurrant product regulated the microbiota of volunteers and decreased the activity of βeta glucuronidase.Feb 28, 2014

Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.Mar 01, 2006

Antineoplastons (A10 Injection and AS2-1) might be useful as adjunctive therapy in addition to HAI after hepatectomy in colorectal metastases to the liver.Dec 31, 2014

Beta-cryptoxanthin synergistically enhances the antitumoral activity of oxaliplatin.Sep 30, 2015

Coffee consumption was associated with 26% lower odds of developing colorectal cancer.Mar 31, 2016

High dose folic acid supplementation is associated with a significant reduction in the recurrrence of colon cancers. Jul 28, 2008

Higher consumption of nuts may be associated with a significantly reduced incidence of cancer recurrence and death in patients with stage III colon cancer.Feb 27, 2018

Higher dietary glycemic load and total carbohydrate intake were statistically significant associated with an increased risk of recurrence and mortality in stage III colon cancer patients.Nov 20, 2012

Individuals consuming the highest intakes of dietary fiber have reduced risks of incident colorectal adenoma and distal colon cancer.Aug 11, 2015

Myofascial pain as assessed by tender trigger points and 25(OH)D deficiency showed a significant association with cancer.Jul 05, 2017

Plaintain seeds improve the colonic flora and butyrate in patients resected for colonic cancer.Oct 01, 1996

Sulforaphane has a novel chemopreventive mechanism in human colon cancer cells and prostate epithelial cells, namely the inhibition of histone deacetylase (HDAC). IFeb 01, 2007

The consumption of apples is inversely related to the risk of colorectal cancer. Jan 01, 2009

This study reports that a meat and sugary dietary pattern increased, while a plant-based dietary pattern decreased the risk of colorectal cancer. Dec 31, 2014

Total vegetable intake, total fruit intake, and lettuce, apple, and banana consumption is associated with a reduced risk for colorectal cancer.Jan 01, 1996

6-gingerol a component of ginger is extensively metabolized in H-1299 human lung cancer cells.Nov 13, 2012

Morus alba flavonoid extract and doxorubicin induce a dose dependent cell death in HT-29 cell line.Mar 30, 2016

Probiotic lactobacillus had inhibitory effects of on the growth of human colonic carcinoma cell line HT-29.Jan 09, 2017

Silybin counteracts doxorubicin resistance by inhibiting GLUT1 expression.Dec 31, 2017

Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.Jan 01, 2018

Sulforaphane regulates xenobiotic metabolism phase II and III enzymes differently in colorectal cancer and untransformed epithelial colon cells.Oct 31, 2016

The present study shows that lichen compounds demonstrated strong antioxidant, antimicrobial, and anticancer properties.Oct 14, 2012

The present work emphasizes the potential of berries in chemoprevention, especially CRC chemoprevention.Dec 31, 2014

verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells. Aug 31, 2015

Wogonin decreased the expression of glycolysis-related proteins, glucose uptake and lactate generation in a dose-dependent manner.Jan 31, 2014

"Phase I clinical studies of antineoplaston A3 injections."Jan 01, 1987

Case report: long-term survival following treatment with antineoplastons for colon cancer with unresectable multiple liver metastases.Jan 01, 2003

Spontaneous regression of colorectal liver metastasis.Jul 31, 2018

Spontaneous regression of transverse colon cancer with high-frequency microsatellite instability.Jan 14, 2019

Spontaneous regression of transverse colon cancer: a case report.Nov 30, 2017

This is the first report showing complete regression of a colon adenoma after intratumoural injection with Viscum album extract.Nov 30, 2014

"Antineoplaston AS2-1 showed an antimetastatic effect against post-operative lung metastases from colon cancer through G1 cell arrest and the subsequent induction of apoptosis."Mar 01, 2005

"Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo.Dec 21, 2010

"Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo."Dec 21, 2010

3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.Jan 31, 2019

A combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.Jan 01, 2010

A compound found exclusively in irradiated dietary fats may promote colon carcinogenesis in animals treated with a chemical carcinogen.Jan 01, 2002

A high vitamin D diet reduced proliferation, increased differentiation and apoptosis, and in parallel, upregulated mRNA expression of the calcium-sensing receptor in the colon of mice.Mar 06, 2015

A sucrose-rich diet induces mutations in the rat colon.Aug 01, 2002

A water-extracted polysaccharide from Lentinus edodes exerts direct antitumor effects by inducing apoptosis in colon cancer cells.Nov 20, 2016

A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.Nov 01, 2001

Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.Mar 14, 2017

Acute addition of Vitamin C to the basolateral membrane maintains low intracellular pH for a longer period which could halt or prevent tumor formation.Dec 31, 2016

Adenosine and P. distasonis have previously been shown to be anti-inflammatory in the colon and we postulate their reduction could promote tumorigenesis by de-repressing inflammation.Jan 31, 1973

Adlay bran ethanolic extract suppressed 1,2-dimethylhydrazine-indued preneoplastic lesions of the colon.Jul 13, 2010

Aged garlic extract suppressed the proliferative activity in adenoma and adenocarcinoma lesions, but showed no effect on normal colon mucosa.Feb 28, 2015

American ginseng exerts the chemopreventive effects by anti-inflammatory and antioxidant mechanisms. Aug 06, 2015

An aqueous extract of fermented barley with Lactobacillus plantarum dy-1 had a greater apoptotic rate than 5-fluorouracil.Dec 31, 2016

An extract of Curcuma purpurascens suppressed the proliferation of HT-29 colon cancer cells and triggered the induction of apoptosis through mitochondrial-dependent pathway.Dec 31, 2014

Annatto has possible chemopreventive effects through modulation of the cryptal cell proliferation but not at the initiation stage of colon carcinogenesis.Apr 03, 2005

Anthocyanin containing purple fleshed potatoes suppressed colon tumorigenesis via elimination of colon cancer stem cells.Aug 13, 2015

Anti-proliferative effect of leaf extracts of Eucalyptus citriodora against human cancer cells in vitro and in vivo.Nov 30, 2012

Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.Dec 31, 2016

Apigenin could inhibit the growth of cisplatin-resistant colon cancer cells in vitro and in vivo.Feb 28, 2019

Apple juice upregulates antioxidant-associated genes in the rat colon and liver, which may account for apple's anti-cancer activity.Aug 01, 2000

Apple pectin and Bifidobacterium longum inhibit colorectal tumors in transgenic mice. Oct 01, 2000

Apple pectin decrease the number and incidence of colon cancer. Mar 01, 1997

Apple polysaccharide extracts could be used in combination therapy for the prevention of colitis-associated colon cancer.Dec 31, 2014

Apple total triterpenoid content induced apoptosis in MDA-MB-231 cells.Sep 18, 2012

Apples may exert their colon cancer protective effects through favorably altering gene patterns resulting in protection of cells against toxicological insults. Jun 15, 2008

Application of an unrestricted ketogenic diet delayed tumor growth in a mouse xenograft model.Dec 31, 2014

As mono-therapy the natural isoflavone genistein has a powerful therapeutic effect in vivo on A431 and Colo205 tumors.Apr 06, 2016

Asiatic acid could be used as an effective chemopreventive agent against 1,2-dimethylhydrazine induced colon carcinogenesis.Dec 24, 2017

Asiatic acid could be used as an effective chemopreventive agent against 1,2-dimethylhydrazine-induced colon carcinogenesis.Jan 31, 2017

Astaxanthin exhibits anti-inflammatory and anti-cancer activity in a rat model of colon cnacer.Apr 01, 2011

Astaxanthin protects against chemically induced colonic pre-neoplastic progression in rats.Apr 01, 2009

Bacopa monieri has great potential for development of anticancer treatments.Sep 30, 2017

Baicalein exerts potent S phase cell cycle arrest and pro-apoptotic effects in HCT-116 cells.Oct 31, 2015

Bee venom could be applicable as an anti-colon cancer agent.Oct 29, 2015

Colon Cancer

View the Evidence:
845 Abstracts with Colon Cancer Research