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Colorectal Cancer
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503 Substances Researched for Colorectal Cancer
Name
AC
CK
Focus
Curcumin
101
187
Flavonoids
30
125
Vitamin D
23
122
Apples
13
84
Coffee
8
73
Quercetin
8
58
Apigenin
8
56
Magnesium
4
42
Vegetables: All
4
42
Probiotics
16
41
Fruit: All
3
40
Vitamin C
19
37
Resveratrol
22
35
Fiber
10
33
Green Tea
6
33
Sulforaphane
16
33
Nuts
4
32
Ginsenosides
21
31
Fermented Foods and Beverages
14
30
Garlic
8
27
Vitamin E
6
27
Ginger
9
25
Beans: All
4
24
Polyphenols
16
24
Silibinin
9
24
Yoghurt
3
24
Lettuce
3
23
Antineoplastons
3
22
Astragalus
2
22
Berberine
14
22
Catechin
6
22
Anthocyanins
14
21
Banana
2
21
Fisetin
9
21
Fish Oil
3
21
Fucoidan
11
21
Soy
7
21
Chinese Skullcap
1
20
Cruciferous Vegetables
1
20
Flavan-3-ols
1
20
Hedyotis corymbosa
1
20
Riboflavin (Vitamin B-2)
1
20
Wheat Germ
2
20
Black Raspberry
7
19
Omega-3 Fatty Acids
6
19
EGCG (Epigallocatechin gallate)
11
18
Pomegranate
6
18
Ellagic Acid
9
17
Bifidobacterium Longum
3
16
Black Currant
3
16
Ginseng
6
16
Parthenolide
9
16
Beta-glucan
4
15
Pterostilbene
10
15
Thymoquinone
11
15
Turmeric
5
15
Blueberry
8
14
Prebiotics
5
14
Walnut
9
14
Aloe Vera
3
13
Luteolin
11
13
Melatonin
4
13
Rice Bran
3
13
Shikonin
8
13
Apple Polyphenols
7
12
Cryptoxanthin
2
12
Folic Acid
2
12
Graviola
3
12
Lentinan
2
12
Lutein
2
12
Onion
3
12
Silymarin
3
12
Vitamin B-6
3
12
Cranberry
5
11
EPA (Eicosapentaenoic Acid)
2
11
Lactoferrin
2
11
Lichens
7
11
Milk Thistle
2
11
Peanut
2
11
Ursolic Acid
10
11
Wogonin
4
11
Artemisinin
1
10
Astaxanthin
5
10
Betaine
1
10
Brazil nuts
1
10
Cannabidiol
6
10
Carnosine
1
10
Choline
1
10
FOS (Fructooligosaccharides)
1
10
Genistein
7
10
Grape
7
10
Leek
1
10
Psyllium
1
10
Sumac
1
10
Turkey Tail Mushroom
1
10
Blackberry
5
9
Chaga Mushroom (Inonotus obliquus)
8
9
Myricetin
7
9
Nobiletin
7
9
Phloretin
5
9
Adlay
6
8
Butyrate
8
8
Chokeberry
4
8
Flaxseed
5
8
Grape Seed Extract
5
8
Lactobacillus casei
4
8
Raspberry
4
8
Rutin
6
8
Sweet Potato
6
8
Bromelain
2
7
Cannabinoids
5
7
Cucurbitacin B
6
7
Fucoxanthin
5
7
Genipin
5
7
Kahweol
3
7
Lignans
5
7
Limonoids
2
7
Mushrooms: All
3
7
Nigella sativa (aka Black Seed)
4
7
Sweet Potato: Purple
5
7
Apple Pectin
2
6
Asiatic Acid
5
6
Baicalein
5
6
Bee Propolis
4
6
Caffeic Acid
4
6
Calcium
3
6
Carotenoids
4
6
Deguelin
4
6
Gingerol
2
6
Guar gum
2
6
Honey
5
6
Isoflavones
4
6
Lingonberry
2
6
Mustard: Field/Turnip
2
6
Olive
5
6
Reishi Mushroom
4
6
Rosemary
5
6
Tanshinone IIA
6
6
Tocotrienol: Gamma
2
6
Andrographis
3
5
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
2
5
Brown Rice
3
5
Cannabis
3
5
Capsaicin
3
5
Carnosic Acid
4
5
Carrot
4
5
Chrysin
4
5
Curry Leaves
3
5
Endocannabinoids
1
5
Feverfew
1
5
Ginseng (Korean)
4
5
Gold (nanoparticles)
5
5
Indian Gooseberry
1
5
Lactobacillus Acidophilus
3
5
Lactobacillus probiotics
1
5
Olive leaf extract
3
5
Oyster Mushroom
4
5
Panaxadiol
1
5
Piperlongumine
4
5
Plantago major
1
5
Prunella vulgaris
4
5
Selenium
3
5
Shiitake Mushroom
3
5
Vitamin A
3
5
Wheat Bran
4
5
Wheat Grass
4
5
White Mulberry
1
5
6-Shogaol
4
4
Allicin
3
4
Apple
3
4
Arctigenin
4
4
Astragaloside
4
4
Betulinic acid
3
4
Bifidobacterium
1
4
Camel Milk
4
4
Cucurbitacin E
3
4
Dandelion
1
4
Ginseng (American)
3
4
Lactobacillus rhamnosus
2
4
Lychee
3
4
Lycopene
4
4
Maitake Mushroom
2
4
Medicinal Mushrooms
3
4
Miso
2
4
Modified Citrus Pectin
2
4
Moringa oleifera
4
4
Oats
3
4
Olive Oil
3
4
P-Coumaric Acid
4
4
Piperine
4
4
Saffron
3
4
Sage
3
4
Spinach
2
4
Urolithin A
3
4
Vitamin B-12
3
4
Vitamin E: Gamma-Tocopherol
2
4
Vitamin E: Gamma-tocotrienol
4
4
Whey
3
4
White Tea
3
4
Xanthohumol
4
4
Acai
2
3
Antineoplaston A3
1
3
Antineoplaston A5
1
3
Antrodia camphorata
3
3
Ashwagandha
2
3
Bacopa
2
3
Berbamine
2
3
Berries: All
3
3
Black Pepper
2
3
Bufalin
3
3
Cannabinoids: Synthetic
3
3
Curcuma Purpurascens
2
3
Cyanidin 3-glucoside
3
3
Emodin
2
3
Frankincense
2
3
Gallic Acid
2
3
Garlic: Aged
2
3
Ginkgo biloba
2
3
Guava
2
3
Gynostemma
2
3
Hydroxytyrosol
3
3
Inositol Hexaphosphate
2
3
Kefir
3
3
Lotus
3
3
Mangiferin
2
3
Manuka Honey
3
3
Mastic gum
2
3
Mistletoe
1
3
Naringenin
3
3
Neem
2
3
Nexrutine (Phellodendrom)
2
3
Orange
2
3
Persimmon
2
3
Piceatannol
3
3
Puerarin
2
3
Red Yeast Rice
2
3
Rice
2
3
Rosmarinic acid
2
3
Saccharomyces Boulardii
2
3
Sesamol
2
3
St. Johns Wort
2
3
Strawberry
3
3
Tart Cherry
2
3
Thistle
2
3
Tomato
3
3
Vanillin
2
3
Vitexins
2
3
Wheat: Fermented
3
3
Achiote
1
2
Agaricus Blazei
1
2
Aleurone
2
2
Arginine
1
2
Avenanthramides
2
2
Barley
1
2
Bee Venom
1
2
Bergamot
1
2
Beta-Elemene
2
2
Bifidobacterium animalis
1
2
Black Bean
2
2
Black Tea
1
2
Boswellia
1
2
Broccoli Sprouts
2
2
Brown Rice: Pre-Germinated
1
2
Buckwheat
1
2
Burdock
2
2
Caffeine
1
2
Cannabigerol
1
2
Capparis spinosa (caper)
2
2
Caraway
1
2
Caraway Oil
1
2
Carnosol
2
2
Chickpea
1
2
Chlorophyll
1
2
Cinnamon
2
2
Citrus aurantium
2
2
Cloudberry
1
2
Cocoa
1
2
Coconut
1
2
Common bean
1
2
Coriandrum sativum
1
2
Cumin
1
2
Curcuma phaeocaulis
1
2
Curcumol
1
2
D-Limonene
2
2
DHA (Docosahexaenoic Acid)
2
2
Daidzein
2
2
Damnacanthal
2
2
Estrone
1
2
Eucalyptus
1
2
Evodiamine
1
2
Ferulic acid
2
2
Flaxseed Oil
1
2
Gac
1
2
Garcinia indica
1
2
Gotu Kola
1
2
Grains: All
1
2
Grapefruit
1
2
Guarana
2
2
Hesperidin
1
2
Honokiol
2
2
Isoliquiritigenin
1
2
Jambul
1
2
Jujube
1
2
Lactobacillus Brevis
1
2
Lactobacillus paracasei
2
2
Lactobacillus plantarum
2
2
Legumes
1
2
Lentils
1
2
Lion's Mane (Hericium Erinaceus)
1
2
Lupeol
2
2
Methionine
1
2
Milk: Fermented
2
2
Mustard Greens
1
2
Mustard Seeds
1
2
Nettle
2
2
Nutmeg
1
2
Oak
1
2
Oleanolic acid
1
2
Oleuropein
2
2
Oolong tea
1
2
Orange: Mandarin
1
2
Paeoniflorin
2
2
Palm Oil
1
2
Panax Ginseng
1
2
Panax Notoginseng
2
2
Pectin
1
2
Phellinus Linteus
2
2
Pine Cone
2
2
Pine Needle
2
2
Potato
2
2
Potato: Pigmented
1
2
Prickly Pear Cactus
2
2
Propolis: Brazillian
1
2
Pumpkin Seed Oil/Meal
1
2
Pumpkin Seeds
2
2
Red Wine
1
2
Rhubarb
2
2
Rose
2
2
Rose Hips
2
2
Rosemaric Acid
1
2
Ruta Graveolens
2
2
Rye
1
2
Sea Cucumber
1
2
Solanum Glaucophyllum
1
2
Soy Protein
1
2
Spirulina
2
2
Sprouts
1
2
Stearic Acid (stearate)
1
2
Tangeretin
2
2
Tannic Acid
2
2
Tetrahydrocurcumin
1
2
Theaflavins
2
2
Tocotrienol: Delta
1
2
Toona sinensis
2
2
Tricin
1
2
Verbascoside
2
2
Vitamin D3
1
2
Vitamin E: delta-tocopherol
1
2
Vitamin K
2
2
Vitamin K2
1
2
Water
1
2
Water: Deuterium Depleted
2
2
Watermelon
1
2
Zerumbone
2
2
Alpha-Lipoic Acid
1
1
Amygdalin
1
1
Anandamide
1
1
Angelica
1
1
Apricot Kernel
1
1
Arabinoxylans
1
1
Arnica
1
1
Artesunate
1
1
Asparagus
1
1
Avocado
1
1
Bacillus coagulans
1
1
Bael
1
1
Bai Zhu
1
1
Bamboo
1
1
Banaba
1
1
Beet
1
1
Benzyl isothiocyanate
1
1
Bergamot orange
1
1
Beta Sitosterol
1
1
Beta-sesquiphellandrene
1
1
Bifidobacterium Bifidum
1
1
Bilberry
1
1
Bitter Melon
1
1
Bran
1
1
Brussel sprouts
1
1
CLA (Conjugated Linoleic Acid)
1
1
Carob
1
1
Chamomile
1
1
Cherry: All Varieties
1
1
Chitosan
1
1
Chlorogenic Acid
1
1
Clove
1
1
Cordyceps Militaris
1
1
Corn Silk
1
1
Coumestrol
1
1
Daikon radish
1
1
Daisy
1
1
Diallyl sulfide
1
1
Echinacea
1
1
Egg
1
1
Endive (Cichorium endivia. L )
1
1
Enterodiol
1
1
Enterolactone
1
1
Eugenol
1
1
Euphorbia cotinifolia
1
1
Fennel
1
1
Fenugreek
1
1
Fig
1
1
Folate
1
1
Fruit Peel
1
1
Geraniol
1
1
Ginseng (Asian)
1
1
Ginseng (Siberian)
1
1
Glycitein
1
1
Goji
1
1
Gold
1
1
Grapes
1
1
Guduchi
1
1
Haematococcus pluvialis
1
1
Hawthorn
1
1
Hazelnut
1
1
Homeopathic Medicine: All
1
1
Honeydew (melon)
1
1
Horse Chestnut
1
1
Huaier (Trametes robiniophila murr)
1
1
Indole-3-Carbinol
1
1
Infection/Infectitious Agent Byproducts (Beneficial)
1
1
Iodine
1
1
Isothiocyanates
1
1
Japanese cypress
1
1
Kanuka Honey
1
1
Kimchi
1
1
Lactobacillus fermentum
1
1
Lactobacillus rhamnosus GG
1
1
Lauric acid
1
1
Lime: Key
1
1
Lithospermum erythrorhizon
1
1
MSM (Methylsulfonylmethane)
1
1
Mangosteen
1
1
Maple
1
1
Maple Syrup
1
1
Marijuana
1
1
Melissa (Lemonbalm)
1
1
Molasses
1
1
Mulberry
1
1
Myrica rubra
1
1
Noni
1
1
Oleocanthal
1
1
Oregano
1
1
Oridonin
1
1
Oyster Mushroom: Indian
1
1
Palmitoylethanolamide
1
1
Pea
1
1
Peach
1
1
Pear
1
1
Peppermint
1
1
Phenethyl isothiocyanate
1
1
Phyllanthus emblica
1
1
Phytosterols
1
1
Piperidines
1
1
Plantago
1
1
Plum
1
1
Polyunsaturated Fatty Acids (PUFAs)
1
1
Pomegranate flower
1
1
Propionibacterium freudenreichii
1
1
Psychedelics:All
1
1
Pumpkin
1
1
Purple Carrots
1
1
Purslane
1
1
Radish
1
1
Raisins
1
1
Red Sage
1
1
Rice: Black
1
1
Rooibos
1
1
Royal Jelly
1
1
Salvia divinorum
1
1
Sea buckthorn
1
1
Sesame Seeds
1
1
Solasodine glycoalkaloids
1
1
Sorghum
1
1
Spearmint
1
1
Stevia
1
1
Stilbenes
1
1
Sweet Cherry
1
1
Tansy
1
1
Thyme
1
1
Thymol
1
1
Toad
1
1
Trichosanthes Kirilowii
1
1
Triphala
1
1
Tyrosol
1
1
Ume (Japanese apricot)
1
1
Vitex Agnus
1
1
Wasabi
1
1
Willow Bark
1
1
Xanthones
1
1
Yam
1
1
Yerba Mate
1
1
pistachios
1
1
34 Problem Substances Researched for Colorectal Cancer
Name
AC
CK
Focus
Meat
4
41
Sugar Sweetened Beverages
2
22
Hydrogenated Oil
2
20
Statin Drugs
2
20
FOLFOX
1
10
Foods: High Glycemic Load
1
10
Heterocyclic Aromatic Amine
1
10
Irinotecan
1
10
Persistent organic pollutants (POPs)
1
10
Tamoxifen
1
10
Casein
2
4
Sucrose
2
4
Bisphenol A
3
3
Benzo(a)pyrene
1
2
Chlorinated Water
1
2
Ferrous Fumarate
1
2
Fluorouracil (5-FU or f5U)
1
2
Fructose
1
2
Glucose
1
2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
1
2
Organochlorine pesticides
1
2
Sodium lauryl sulfate
1
2
2,4-Dichlorophenoxyacetic acid
1
1
Adrenaline
1
1
Aromatase Inhibitor Drugs
1
1
Artificial Sweeteners
1
1
Aspartame
1
1
Atorvastatin
1
1
Bisphosphonates
1
1
Doxorubicin
1
1
Nicotine
1
1
Pesticides
1
1
Saccharin
1
1
Sodium Cyclamate
1
1
12 Therapeutic Actions Researched for Colorectal Cancer
Name
AC
CK
Focus
Sunlight exposure
3
43
Exercise
4
32
Dietary Modification: Mediterranean Diet
2
20
Aromatherapy Massage
1
10
Massage/Therapeutic Touch
1
10
Light-Emitting Diodes (LEDs) Therapy
2
3
Dietary Modification: Low Carbohydrate/Ketogenic
1
2
Fasting/Caloric Restriction
1
2
Light Therapy
1
2
Microbiota Transfer Therapy
2
2
Thermal Therapy: Far-Infrared
1
2
Heat Therapy
1
1
7 Problematic Actions Researched for Colorectal Cancer
Name
AC
CK
Focus
Western Diet
9
28
Chemotherapy
1
10
Fine Needle Aspiration
1
3
Gamma Irradiation: "Cold Pasteurization"
1
2
Microwave Cooking
1
1
Radiotherapy
1
1
Stress
1
1
Research Articles
1192
Cumulative Knowledge Score
1928
Overall Research Rating
EXCELLENT
Related Topics
The Following are Sub-Topics of Colorectal Cancer
Colon Cancer
Rectal Cancer
View the Evidence:
1599 Abstracts with Colorectal Cancer Research
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[+]
"Dietary flavonoid for preventing colorectal neoplasms."
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Cochrane Database Syst Rev. 2012 ;8:CD009350. Epub 2012 Aug 15. PMID:
22895989
Article Published Date
: Dec 31, 2011
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
[+]
A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:2417418. Epub 2019 Dec 17. PMID:
31929811
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
,
Esophageal Cancer
,
Gastric Cancer
,
Liver Cancer
,
Pancreatic Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.
Sep 25, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Sep 26 ;6:33711. Epub 2016 Sep 26. PMID:
27665923
Article Published Date
: Sep 25, 2016
Study Type
: Meta Analysis
Additional Links
Substances
:
Coffee
Diseases
:
Colon Cancer
,
Endometrial Cancer
,
Liver Cancer
,
Lung Cancer
,
Melanoma
,
Oral Cancer
,
Prostate Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Colorectal cancer was associated with a lower concentration of serum vitamin E in this meta-analysis of case studies.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Medicine (Baltimore). 2017 Jul ;96(27):e7470. PMID:
28682917
Article Published Date
: Jun 30, 2017
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin E
Diseases
:
Colorectal Cancer
,
Vitamin E Deficiency
Additional Keywords
:
Risk Factors
[+]
Consumption of apples is associated with a reduced risk of cancer in different anatomical sites.
Mar 21, 2016
Click here to read the entire abstract
Pubmed Data
: Public Health Nutr. 2016 Mar 22:1-15. Epub 2016 Mar 22. PMID:
27000627
Article Published Date
: Mar 21, 2016
Study Type
: Meta Analysis
Additional Links
Substances
:
Apples
Diseases
:
Breast Cancer
,
Colorectal Cancer
,
Esophageal Cancer
,
Oral Cancer
Additional Keywords
:
Risk Reduction
[+]
Garlic intake could reduce the risk of colorectal cancer.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicine (Baltimore). 2020 Jan ;99(1):e18575. PMID:
31895803
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis
Additional Links
Substances
:
Garlic
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
High intake of flavonols may reduce the risk of colon cancer and high intake of flavones may reduce the risk of rectal cancer.
Jul 22, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Jul 23 ;10(7). Epub 2018 Jul 23. PMID:
30041489
Article Published Date
: Jul 22, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Quercetin
Diseases
:
Colorectal Cancer
,
Rectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Higher dietary magnesium intake seems to have a protective effect for cancer, especially colorectal cancer and in females.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2014 ;66(6):915-23. Epub 2014 Jun 9. PMID:
24910891
Article Published Date
: Dec 31, 2013
Study Type
: Meta Analysis
Additional Links
Substances
:
Magnesium
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Additional Keywords
:
Risk Reduction
[+]
Meta-analysis demonstrates a clinically meaningful benefit of vitamin D supplementation on colorectal cancer survival outcomes.
Sep 14, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Cancer. 2020 Sep 15. Epub 2020 Sep 15. PMID:
32929196
Article Published Date
: Sep 14, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Vitamin D
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemotherapeutic
[+]
Nut consumption was significantly associated with a reduced risk of cancer incidence.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Rev. 2015 Jul ;73(7):409-25. PMID:
26081452
Article Published Date
: Jun 30, 2015
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Nuts
Diseases
:
Colon Cancer
,
Pancreatic Cancer
Additional Keywords
:
Risk Reduction
[+]
Preoperative C-reactive protein and its related markers, GPS and mGPS, were significantly associated with the survival of colorectal cancer surgery patients.
Sep 15, 2015
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2015 Sep 16. Epub 2015 Sep 16. PMID:
26376895
Article Published Date
: Sep 15, 2015
Study Type
: Meta Analysis
Additional Links
Diseases
:
C-Reactive Protein
,
Colorectal Cancer
[+]
Prolonged television viewing, occupational sitting time, and total sitting time are associated with increased risks of colorectal cancer.
May 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicine (Baltimore). 2017 Jun ;96(22):e7049. PMID:
28562564
Article Published Date
: May 31, 2017
Study Type
: Meta Analysis
Additional Links
Diseases
:
Colorectal Cancer
,
Sitting Sickness
Additional Keywords
:
Increased Risk
,
Risk Factors
[+]
Review: there is a consistently strong inverse correlations with solar UVB for 15 types of cancers.
Jan 01, 2012
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2012 Jan ;32(1):223-36. PMID:
22213311
Article Published Date
: Jan 01, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin D
Diseases
:
Bladder Cancer
,
Breast Cancer
,
Cervical Cancer
,
Colon Cancer
,
Colorectal Cancer
,
Endometrial Cancer
,
Esophageal Cancer
,
Hodgkin Lymphoma
,
Lung Cancer
,
Non-Hodgkin Lymphoma
,
Ovarian Cancer
,
Pancreatic Cancer
,
Renal Cancer
,
Vulvar Cancer
Therapeutic Actions
:
Sunlight exposure
Pharmacological Actions
:
Chemopreventive
[+]
Specific combinations of traditional medicines appeared to produce higher contributions to tumor response rate than the TMs individually.
Aug 05, 2015
Click here to read the entire abstract
Pubmed Data
: Integr Cancer Ther. 2015 Aug 6. Epub 2015 Aug 6. PMID:
26254190
Article Published Date
: Aug 05, 2015
Study Type
: Meta Analysis
Additional Links
Substances
:
Astragalus
,
Chinese Skullcap
,
Hedyotis corymbosa
Diseases
:
Colorectal Cancer
Additional Keywords
:
Drug: Oxaliplatin
,
Natural Substance/Drug Synergy
[+]
These analysis indicates the potential benefits of flavan-3-ols in cancer prevention.
Nov 07, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Nov 8 ;7(45):73573-73592. PMID:
27634884
Article Published Date
: Nov 07, 2016
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavan-3-ols
Diseases
:
Laryngeal Cancer
,
Rectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
This study provides support that cruciferous vegetable intake protects against cancer of the colon and the significance of gene diet interactions.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2014 ;66(1):128-39. Epub 2013 Dec 16. PMID:
24341734
Article Published Date
: Dec 31, 2013
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cruciferous Vegetables
Diseases
:
Colorectal Cancer
,
Digestive System Neoplasms
Additional Keywords
:
Risk Reduction
[+]
Vitamin B2 intake was inversely associated with risk of colorectal cancer.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2015 ;16(3):909-13. PMID:
25735381
Article Published Date
: Dec 31, 2014
Study Type
: Meta Analysis
Additional Links
Substances
:
Riboflavin (Vitamin B-2)
Diseases
:
Colorectal Cancer
Additional Keywords
:
Risk Reduction
[+]
A blackcurrant product regulated the microbiota of volunteers and decreased the activity of βeta glucuronidase.
Feb 28, 2014
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2014 Mar ;28(3):416-22. Epub 2013 May 15. PMID:
23674271
Article Published Date
: Feb 28, 2014
Study Type
: Human Study
Additional Links
Substances
:
Black Currant
,
Lactoferrin
,
Lutein
,
Prebiotics
Diseases
:
Clostridium Infections
,
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Enzyme Inhibitors
Additional Keywords
:
Beta-glucuronidase
,
Plant Extracts
,
Risk Reduction
[+]
A combination of apigenin and EGCG prevent colorectal cancer recurrence.
Apr 14, 2008
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2008 Apr 14;14(14):2187-93. PMID:
18407592
Article Published Date
: Apr 14, 2008
Study Type
: Human Study
Additional Links
Substances
:
Apigenin
,
Catechin
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut.
Jan 01, 2005
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):120-5. PMID:
15668484
Article Published Date
: Jan 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Antineoplastic Agents
[+]
A fermented wheat germ extract significantly improves the outcome of patients with colorectal cancer.
Sep 11, 2005
Click here to read the entire abstract
Pubmed Data
: Orv Hetil. 2005 Sep 11;146(37):1925-31. PMID:
16255377
Article Published Date
: Sep 11, 2005
Study Type
: Human Study
Additional Links
Substances
:
Wheat Germ
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Drug synergy
[+]
A flavonol-rich diet may decrease the risk of advanced adenoma recurrence.
May 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2008 Jun ;17(6):1344-53. PMID:
18559549
Article Published Date
: May 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
A lacto probiotic product reduced up to 79.82% the induction of aberrant crypt foci by 1,2-dimethylhydrazine.
Mar 21, 2017
Click here to read the entire abstract
Pubmed Data
: Genet Mol Res. 2017 Mar 22 ;16(1). Epub 2017 Mar 22. PMID:
28340269
Article Published Date
: Mar 21, 2017
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
,
Yoghurt
Diseases
:
Colorectal Cancer
,
DNA damage
Pharmacological Actions
:
Anticarcinogenic Agents
,
Genoprotective
Additional Keywords
:
Risk Reduction
[+]
Abstaining from excessive consumption of meat might be protective against developing colorectal cancer.
Apr 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Sci. 2017 May ;108(5):1065-1070. Epub 2017 May 16. PMID:
28256076
Article Published Date
: Apr 30, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Problem Substances
:
Meat
[+]
Adjuvant tamoxifen therapy for early stage breast cancer increases the risk of second primarly malignancies such as endometrial, colon and somatch cancer.
May 03, 1995
Click here to read the entire abstract
Pubmed Data
: J Natl Cancer Inst. 1995 May 3;87(9):645-51. PMID:
7752269
Article Published Date
: May 03, 1995
Study Type
: Human Study
Additional Links
Diseases
:
Breast Cancer
,
Colorectal Cancer
,
Endometrial Cancer
,
Gastric Cancer
Additional Keywords
:
Drug: Tamoxifen
Problem Substances
:
Tamoxifen
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.
Mar 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2006 Mar;136(3 Suppl):816S-820S. PMID:
16484572
Article Published Date
: Mar 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Garlic
Diseases
:
Colon Cancer
,
Liver Cancer
,
Low Immune Function: Natural Killer Cells
,
Pancreatic Cancer
Additional Keywords
:
Drug Side Effect Attenuation
,
Plant Extracts
[+]
Allium vegetables are associated with reduced risk of colorectal cancer.
Feb 19, 2019
Click here to read the entire abstract
Pubmed Data
: Asia Pac J Clin Oncol. 2019 Feb 20. Epub 2019 Feb 20. PMID:
30790463
Article Published Date
: Feb 19, 2019
Study Type
: Human Study
Additional Links
Substances
:
Garlic
,
Leek
,
Onion
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Aloe significantly improves chemotherapy treatment coutcomes in patients with metastatic gastric, pancreatic and colorectal cancers.
Jan 01, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: In Vivo. 2009 Jan-Feb;23(1):171-5. PMID:
19368145
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Cancer Metastasis
,
Cancers: All
,
Colorectal Cancer
,
Gastric Cancer
,
Pancreatic Cancer
Additional Keywords
:
Drug-Plant-Vitamin Synergies
[+]
Antineoplastons (A10 Injection and AS2-1) might be useful as adjunctive therapy in addition to HAI after hepatectomy in colorectal metastases to the liver.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(3):e0120064. Epub 2015 Mar 19. PMID:
25790229
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Antineoplastons
Diseases
:
Cancer Metastasis
,
Colon Cancer
,
Colorectal Cancer
Additional Keywords
:
Drug: 5-flourouracil
,
Significant Treatment Outcome
[+]
Aromatherapy with light Thai massage can be beneficial for the immune systems of cancer patients who are undergoing chemotherapy.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2013 ;14(6):3903-7. PMID:
23886205
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Ginger
Diseases
:
Colorectal Cancer
Therapeutic Actions
:
Aromatherapy Massage
Pharmacological Actions
:
Immunomodulatory
[+]
Artesunate has anti-proliferative properties in colorectal cancer and is generally well tolerated.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: EBioMedicine. 2015 Jan ;2(1):82-90. Epub 2014 Nov 15. PMID:
26137537
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Artemisinin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Associations of physical activity with survival and progression in metastatic colorectal cancer.
Aug 12, 2019
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2019 Aug 13:JCO1901019. Epub 2019 Aug 13. PMID:
31408415
Article Published Date
: Aug 12, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Chemotherapeutic
[+]
Baduanjin qigong exercise can relieve cancer-related fatigue in patients with colorectal cancer undergoing chemotherapy.
Jul 01, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Res Treat. 2019 Jul 2:1-7. Epub 2019 Jul 2. PMID:
31266043
Article Published Date
: Jul 01, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Cancer: Fatigue
,
Colorectal Cancer
Therapeutic Actions
:
Qigong
Pharmacological Actions
:
Chemotherapeutic
[+]
Berberine was safe and effective in reducing the risk of recurrence of colorectal adenoma.
Jan 07, 2020
Click here to read the entire abstract
Pubmed Data
: Lancet Gastroenterol Hepatol. 2020 Jan 8. Epub 2020 Jan 8. PMID:
31926918
Article Published Date
: Jan 07, 2020
Study Type
: Human Study
Additional Links
Substances
:
Berberine
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Beta glucan is safe and effective for suppressing the adverse effects of chemotherapy and improving quality of life in patients with colorectal cancer.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2009 Jul;29(7):2611-7. PMID:
19596936
Article Published Date
: Jul 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Beta-glucan
,
Lentinan
Diseases
:
Colorectal Cancer
[+]
Beta-cryptoxanthin synergistically enhances the antitumoral activity of oxaliplatin.
Sep 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Cancer Res. 2015 Oct 1 ;21(19):4398-409. Epub 2015 May 28. PMID:
26023082
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study, Human Study, In Vitro Study
Additional Links
Substances
:
Cryptoxanthin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
Additional Keywords
:
Chemotherapeutic Synergy: Oxaliplatin
[+]
Choline, betaine, and choline-containing compounds was inversely associated with colorectal cancer risk.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(3):e0118661. Epub 2015 Mar 18. PMID:
25785727
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Betaine
,
Choline
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Chronic exposure to low-dose persistent organic pollutants may be associated with an increased risk of colorectal polyps and cancer.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2018 ;13(12):e0208546. Epub 2018 Dec 6. PMID:
30521631
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Additional Keywords
:
Increased Risk
Problem Substances
:
Persistent organic pollutants (POPs)
[+]
Coffee consumption was associated with 26% lower odds of developing colorectal cancer.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2016 Apr ;25(4):634-9. PMID:
27196095
Article Published Date
: Mar 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Coffee
Diseases
:
Colon Cancer
,
Rectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Dose Response
,
Risk Reduction
[+]
Coffee drinking is associated with a lower risk of colorectal, liver, female breast and head and neck cancer.
Jul 26, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2017 Jul 27. Epub 2017 Jul 27. PMID:
28751477
Article Published Date
: Jul 26, 2017
Study Type
: Human Study
Additional Links
Substances
:
Coffee
Diseases
:
Breast Cancer
,
Cancer Mortality
,
Cancers: All
,
Colorectal Cancer
,
Head and Neck Cancer
,
Liver Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia.
May 16, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 May 17. Epub 2018 May 17. PMID:
29770393
Article Published Date
: May 16, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colorectal Cancer
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Curcumin is a safe and tolerable adjunct to FOLFOX chemotherapy in patients with metastatic colorectal cancer.
May 26, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr. 2019 May 27. Epub 2019 May 27. PMID:
31132111
Article Published Date
: May 26, 2019
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Pharmacological Actions
:
Chemotherapeutic
[+]
Decreased serum 25(OH)D levels in CRC are associated with serrated tumor morphology, and systemic inflammatory response.
Nov 06, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Nov 7 ;6:36519. Epub 2016 Aug 7. PMID:
27819306
Article Published Date
: Nov 06, 2016
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Colorectal Cancer
,
Inflammation
Additional Keywords
:
Risk Factors
[+]
Diet-associated inflammation may increase the risk of colorectal cancer.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutrients. 2016;8(8). Epub 2016 Jul 30. PMID:
27483316
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Gastrointestinal Inflammation
,
Inflammation
Additional Keywords
:
Risk Factors
[+]
Dietary supplementation with rice bran alters gut bacterial metabolism in colorectal cancer survivors.
Jul 26, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2016 Jul 27. Epub 2016 Jul 27. PMID:
27461523
Article Published Date
: Jul 26, 2016
Study Type
: Human Study
Additional Links
Substances
:
Rice Bran
Diseases
:
Colorectal Cancer
Additional Keywords
:
Microbiota
[+]
Dosage Study: A daily dose of 3.6 g of curcumin engendered 62% and 57% decreases in inducible PGE(2) production in blood samples taken 1 hour after dose on days 1 and 29, respectively, in patients with advanced colorectal cancer.
Oct 15, 2004
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2004 Oct 15;10(20):6847-54. PMID:
15501961
Article Published Date
: Oct 15, 2004
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Prostaglandin PGE2 downregulation
[+]
Dosage Study: Turmeric extract can be administered safely to patients at doses of up to 2.2 g daily, equivalent to 180 mg of curcumin.
Jul 01, 2001
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2001 Jul;7(7):1894-900. PMID:
11448902
Article Published Date
: Jul 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Turmeric
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Plant Extracts
[+]
Dry bean consumption may be inversely associated with advanced adenoma recurrence.
Jun 21, 2008
Click here to read the entire abstract
Pubmed Data
: Int Urol Nephrol. 2008 Jun 21. PMID:
16772456
Article Published Date
: Jun 21, 2008
Study Type
: Human Study
Additional Links
Substances
:
Beans: All
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Dysbiosis might worsen the patients' prognosis with colorectal cancer by up-regulating gut inflammation level.
Jun 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jun 15. Epub 2016 Jun 15. PMID:
27323816
Article Published Date
: Jun 14, 2016
Study Type
: Human In Vitro, Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Dysbiosis
,
Gastrointestinal Inflammation
Additional Keywords
:
Risk Factors
[+]
Effect and mechanism of vitamin D on the development of colorectal cancer based on intestinal flora disorder.
Nov 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Gastroenterol Hepatol. 2019 Dec 1. Epub 2019 Dec 1. PMID:
31788852
Article Published Date
: Nov 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Colorectal Cancer
,
Vitamin D Deficiency
Pharmacological Actions
:
Chemopreventive
,
Gastrointestinal Agents
[+]
Effect of orally administered bovine lactoferrin on the growth of adenomatous colorectal polyps.
Oct 31, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2009 Nov ;2(11):975-83. Epub 2009 Oct 27. PMID:
19861543
Article Published Date
: Oct 31, 2009
Study Type
: Human Study
Additional Links
Substances
:
Lactoferrin
Diseases
:
Colon Polyps
,
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Engaging in Physical activity may be an effective approach to increase the vitamin D levels in patients with colorectal cancer.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2017 Feb-Mar;69(2):229-237. Epub 2017 Jan 17. PMID:
28094599
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Colorectal Cancer
,
Vitamin D Deficiency
Therapeutic Actions
:
Exercise
Additional Keywords
:
Physical Activity
[+]
Fermented wheat germ has therapeutic value in the treatment of colorectal cancer.
Mar 01, 2000
Click here to read the entire abstract
Pubmed Data
: Hepatogastroenterology. 2000 Mar-Apr;47(32):393-5. PMID:
10791198
Article Published Date
: Mar 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Wheat Germ
Diseases
:
Colorectal Cancer
Additional Keywords
:
Lectins
,
Plant Extracts
[+]
Fisetin could improve the inflammatory status in colorectal cancer patients.
Mar 14, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 Mar 15. Epub 2018 Mar 15. PMID:
29541713
Article Published Date
: Mar 14, 2018
Study Type
: Human Study
Additional Links
Substances
:
Fisetin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemotherapeutic
,
Interleukin-8 downregulation
,
Matrix Metalloproteinase-7 (MMP-7) Inhibitor
[+]
Fish oil supplementation may improve symptom-related quality of life in stage 2 CRC patients following diagnosis.
Sep 17, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Sep 18:1-8. Epub 2015 Sep 18. PMID:
26380892
Article Published Date
: Sep 17, 2015
Study Type
: Human Study
Additional Links
Substances
:
Fish Oil
Diseases
:
Colorectal Cancer
,
Quality of Life: Poor
Pharmacological Actions
:
Chemotherapeutic
[+]
Flavonoids from vegetables and fruits may be linked with the reduced risk of colorectal cancer.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2016 Oct ;116(7):1275-1287. Epub 2016 Sep 21. PMID:
27650133
Article Published Date
: Sep 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Vegetables: All
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Additional Keywords
:
COLORECTAL CANCER
,
Colorectal Cancer: Prevention
,
Flavonoids
,
Fruit: All
,
Risk Reduction
,
Vegetables: All
[+]
FOLFIRI and FOLFOX6 chemotherapies result in a median progression free survival time of between 7.7 and 8.4 months.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Jpn J Clin Oncol. 2010 Jul;40(7):634-8. PMID:
20587616
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
Additional Keywords
:
Drug: 5-flourouracil
Anti Therapeutic Actions
:
Chemotherapy
[+]
FOLFOX4 results in extraordinarily high rates of adverse reactions: peripheral neuropathy (82 %), neutropenia (56.4 %) and diarrhoea (53.9 %.)
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Farm Hosp. 2009 Mar-Apr;33(2):89-95. PMID:
19480796
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Additional Keywords
:
Drug: 5-flourouracil
Problem Substances
:
FOLFOX
[+]
Foot reflexology was effective in reducing pain and fatigue level in people with colorectal cancer who received chemoradiotherapy.
Feb 06, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Nurs Pract. 2017 Feb 7. Epub 2017 Feb 7. PMID:
28176423
Article Published Date
: Feb 06, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Fatigue: Cancer-Associated
Therapeutic Actions
:
Massage/Therapeutic Touch
[+]
Frequent intake of peanut and its products may reduce colorectal cancer risk in women.
Jan 13, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2006 Jan 14 ;12(2):222-7. PMID:
16482621
Article Published Date
: Jan 13, 2006
Study Type
: Human Study
Additional Links
Substances
:
Peanut
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Additional Keywords
:
Risk Reduction
[+]
Green tea extracts reduce the size and incidence of recurrence of colorectal cancer in humans.
Nov 01, 2008
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3020-5. PMID:
18990744
Article Published Date
: Nov 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
Diseases
:
Colorectal Cancer
[+]
Heterocyclic aromatic amine intake increases colorectal adenoma risk.
May 01, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2009 May;89(5):1418-24. Epub 2009 Mar 4. PMID:
19261727
Article Published Date
: May 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Problem Substances
:
Heterocyclic Aromatic Amine
[+]
High blood sugar levels significantly impact the prognosis of colorectal cancer patients by decreasing the anti-oncogenic effects of miR-16.
Feb 24, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Feb 25. Epub 2016 Feb 25. PMID:
26934556
Article Published Date
: Feb 24, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Hyperglycemia
Additional Keywords
:
Increased Risk
[+]
High consumption of trans-fatty acids is associated with an increased risk of colorectal cancer.
Aug 01, 2008
Click here to read the entire abstract
Pubmed Data
: Am J Epidemiol. 2008 Aug 1;168(3):289-97. Epub 2008 Jun 27. PMID:
18587137
Article Published Date
: Aug 01, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Problem Substances
:
Hydrogenated Oil
[+]
High consumption of trans-fatty acids was positively associated with distal colorectal cancer among Whites.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2010 Jan;21(1):171-80. Epub 2009 Oct 20. PMID:
19842051
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Problem Substances
:
Hydrogenated Oil
[+]
High dose folic acid supplementation is associated with a significant reduction in the recurrrence of colon cancers.
Jul 28, 2008
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2008 Jul 28;14(28):4492-8. PMID:
18680228
Article Published Date
: Jul 28, 2008
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Higher concentrations of vitamin D were longitudinally associated with better global quality of life and less fatigue in colorectal cancer survivors.
Apr 03, 2020
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2020 Apr 3. Epub 2020 Apr 3. PMID:
32245785
Article Published Date
: Apr 03, 2020
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Colorectal Cancer
,
Fatigue
[+]
Higher consumption of nuts may be associated with a significantly reduced incidence of cancer recurrence and death in patients with stage III colon cancer.
Feb 27, 2018
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2018 Feb 28:JCO2017755413. Epub 2018 Feb 28. PMID:
29489429
Article Published Date
: Feb 27, 2018
Study Type
: Human Study
Additional Links
Substances
:
Nuts
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Chemopreventive
,
COLON CANCER
,
nuts
,
Risk Reduction
[+]
Higher dietary glycemic load and total carbohydrate intake were statistically significant associated with an increased risk of recurrence and mortality in stage III colon cancer patients.
Nov 20, 2012
Click here to read the entire abstract
Pubmed Data
: J Natl Cancer Inst. 2012 Nov 21 ;104(22):1702-11. Epub 2012 Nov 7. PMID:
23136358
Article Published Date
: Nov 20, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Carcinogens
Problem Substances
:
Foods: High Glycemic Load
[+]
Higher levels of circulating chemerin, CRP, fibrinogen, and ESR are associated with an increased risk of developing colorectal cancer.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2015 Dec 1. Epub 2015 Dec 1. PMID:
26628300
Article Published Date
: Nov 30, 2015
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein
,
Colorectal Cancer
,
Inflammation
Additional Keywords
:
Risk Factors
[+]
Increased consumption of green tea might be helpful to reduce the risk of colorectal cancer in those with an unhealthy lifestyle.
Oct 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Nov 1 ;11(11). Epub 2019 Nov 1. PMID:
31683767
Article Published Date
: Oct 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Increased tumor ascorbate is associated with extended disease-free survival and decreased hypoxia-inducible factor-1.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2014 ;4:10. Epub 2014 Aug 4. PMID:
24551593
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Hypoxia-inducible factor-1 (HIF-1) inhibitor
[+]
Individuals consuming the highest intakes of dietary fiber have reduced risks of incident colorectal adenoma and distal colon cancer.
Aug 11, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2015 Aug 12. Epub 2015 Aug 12. PMID:
26269366
Article Published Date
: Aug 11, 2015
Study Type
: Human Study
Additional Links
Substances
:
Fiber
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
,
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Intake of Bifidobacterium longum and Fructo-oligosaccharides prevents colorectal carcinogenesis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Euroasian J Hepatogastroenterol. 2018 Jan-Jun;8(1):11-17. Epub 2018 May 1. PMID:
29963455
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Bifidobacterium Longum
,
FOS (Fructooligosaccharides)
,
Probiotics
,
Yoghurt
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Irinotecan may be linked to an increased risk of hepatic failure and postoperative death.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Bull Cancer. 2010 May;97(5):559-69. PMID:
20167564
Article Published Date
: May 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Problem Substances
:
Irinotecan
[+]
Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemotherapy.
Apr 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Cancer. 2020 May ;130:51-62. Epub 2020 Mar 13. PMID:
32172198
Article Published Date
: Apr 30, 2020
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Cancer: Fatigue
,
Colorectal Cancer
Pharmacological Actions
:
Chemotherapeutic
[+]
L-carnosine protects against oxaliplatin-induced peripheral neuropathy in colorectal cancer patients.
Feb 14, 2019
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2019 Feb 15 ;365:41-50. Epub 2018 Dec 25. PMID:
30592963
Article Published Date
: Feb 14, 2019
Study Type
: Human Study
Additional Links
Substances
:
Carnosine
Diseases
:
Chemotherapy-Induced Toxicity: Oxaliplatin
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Low adherence to the western and high adherence to the mediterranean dietary patterns could prevent colorectal cancer.
Mar 25, 2018
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2018 Mar 26. Epub 2018 Mar 26. PMID:
29582162
Article Published Date
: Mar 25, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Chemopreventive
Anti Therapeutic Actions
:
Western Diet
[+]
Low muscle mass in patients undergoing surgery for colorectal cancer was associated with an increased postoperative inflammatory response.
Jul 15, 2015
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2015 Jul 16. Epub 2015 Jul 16. PMID:
26205321
Article Published Date
: Jul 15, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Inflammation
,
Postoperative Recovery
,
Sarcopenia
Additional Keywords
:
Increased Risk
[+]
Low-molecular-weight fucoidan combined with chemotarget agents significantly improved the disease control rate.
Apr 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2017 Apr 21 ;15(4). Epub 2017 Apr 21. PMID:
28430159
Article Published Date
: Apr 20, 2017
Study Type
: Human Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemotherapeutic
Additional Keywords
:
Chemotherapeutic
,
COLORECTAL CANCER
,
Fucoidan
[+]
Magnesium intake around 400 mg/day from both dietary and supplemental sources is associated with a lower incidence of CRC in postmenopausal women.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2015 Dec ;26(12):1761-9. Epub 2015 Sep 21. PMID:
26390877
Article Published Date
: Nov 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Colorectal Cancer
Additional Keywords
:
Risk Reduction
[+]
Mediterranean dietary components are inversely associated with advanced colorectal polyps.
Jun 27, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2018 Jun 28 ;24(24):2617-2627. PMID:
29962818
Article Published Date
: Jun 27, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Colon Polyps
,
Colorectal Cancer
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Chemopreventive
[+]
Melatonin has a drug sparing and synergistic effect with chemotherapy in the treatment of metastatic colorectal patients.
Mar 01, 2003
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2003 Mar-Apr;23(2C):1951-4. PMID:
12820485
Article Published Date
: Mar 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Melatonin
Diseases
:
Colorectal Cancer
Additional Keywords
:
Drug-Plant-Vitamin Synergies
,
Drug Sparing
[+]
Myofascial pain as assessed by tender trigger points and 25(OH)D deficiency showed a significant association with cancer.
Jul 05, 2017
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2017 Jul 6:1-7. Epub 2017 Jul 6. PMID:
28682182
Article Published Date
: Jul 05, 2017
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
,
Vitamin D
Diseases
:
Colon Cancer
,
Magnesium Deficiency
,
Vitamin D Deficiency
Additional Keywords
:
Risk Factors
[+]
Navy beans impact the stool metabolome and metabolic pathways for colon health in cancer survivors.
Dec 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Dec 22 ;11(1). Epub 2018 Dec 22. PMID:
30583518
Article Published Date
: Dec 21, 2018
Study Type
: Human Study
Additional Links
Substances
:
Beans: All
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
,
Gastrointestinal Agents
[+]
Omega-3 fatty acids exerts anti-inflammatory effects in surgical patients, without reducing the risk of postoperative complications.
Sep 28, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2014 Sep 29 ;6(10):4043-57. Epub 2014 Sep 29. PMID:
25268838
Article Published Date
: Sep 28, 2014
Study Type
: Human Study
Additional Links
Substances
:
EPA (Eicosapentaenoic Acid)
,
Omega-3 Fatty Acids
Diseases
:
Colon Surgery
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Oral cryotherapy prevents oral mucositis and pain among patients with colorectal cancer undergoing chemotherapy.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Clin J Oncol Nurs. 2018 10 1 ;22(5):555-560. PMID:
30239519
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Colorectal Cancer
,
Oral Mucositis
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Chemoprotective Agents
[+]
Oral silibinin, an IGF-1 binder, may result in lowered IGF-1 levels in liver and colorectal cancer patients as indicated by its accumulation in blood and tissue samples.
May 01, 2006
Click here to read the entire abstract
Pubmed Data
: Clin Cancer Res. 2006 May 1;12(9):2944-50. PMID:
16675592
Article Published Date
: May 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Milk Thistle
,
Silibinin
,
Silymarin
Diseases
:
Colorectal Cancer
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Insulin-Like Growth Factor Inhibition/Downregulation
[+]
Participation in strenuous-vigorous physical activity was associated with reduced colorectal cancer risk among Asian populations.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Cancer Prev. 2017 Nov ;26(6):469-475. PMID:
28542077
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Physical Activity
,
Risk Reduction
[+]
Plaintain seeds improve the colonic flora and butyrate in patients resected for colonic cancer.
Oct 01, 1996
Click here to read the entire abstract
Pubmed Data
: Scand J Gastroenterol. 1996 Oct;31(10):1011-20. PMID:
8898423
Article Published Date
: Oct 01, 1996
Study Type
: Human Study
Additional Links
Substances
:
Psyllium
Diseases
:
Colon Cancer
,
Dysbiosis
[+]
Plasma levels of vitamin D is associated with clinically important differences in survival outcome.
Jul 06, 2014
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2014 Jul 7. Epub 2014 Jul 7. PMID:
25002714
Article Published Date
: Jul 06, 2014
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Gene Protective
Additional Keywords
:
Gene Environment
[+]
Prolonged (more than 4 years) use of statins is associated with a significantly increased risk of colorectal cancer bladder cancer and lung cancer.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: BMC Cancer. 2011 ;11:409. Epub 2011 Sep 26. PMID:
21943022
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Bladder Cancer
,
Colorectal Cancer
,
Lung Cancer
,
Statin-Induced Pathologies
Problem Substances
:
Statin Drugs
[+]
Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Clin Oncol. 2017 Nov ;7(5):891-896. Epub 2017 Sep 1. PMID:
29142752
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Colorectal Cancer
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Proton-pump inhibitors are associated with a high false-positivity rate in faecal immunochemical testing.
Nov 06, 2020
Click here to read the entire abstract
Pubmed Data
: J Gastroenterol. 2020 Nov 7. Epub 2020 Nov 7. PMID:
33159805
Article Published Date
: Nov 06, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Additional Keywords
:
False Positives
Problem Substances
:
Proton-Pump Inhibitors
[+]
Repeat hepatic cryotherapy for metastatic colorectal cancer.
Apr 30, 2001
Click here to read the entire abstract
Pubmed Data
: J Gastrointest Surg. 2001 May-Jun;5(3):287-93. PMID:
11360052
Article Published Date
: Apr 30, 2001
Study Type
: Human Study
Additional Links
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Chemotherapeutic
[+]
Resveratrol reduces tumor cell proliferation in colorectal patients.
Feb 01, 2008
Click here to read the entire abstract
Pubmed Data
: Antiviral Res. 2008 Feb;77(2):153-6. Epub 2007 Oct 8. PMID:
20841478
Article Published Date
: Feb 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Stilbenes
[+]
Rhus verniciflua stokes (Sumac) extract postively effects overall survival of patients with colorectal cancer refractory to conventional treatment.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Integr Cancer Ther. 2009 Jun;8(2):148-52. PMID:
19679623
Article Published Date
: Jun 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Sumac
Diseases
:
Cancers: Drug Resistant
,
Colorectal Adenomas
,
Colorectal Cancer
Additional Keywords
:
Antineoplastic Agents
[+]
Shifts in the fecal microbiota are associated with adenomatous polyps.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2017 Jan ;26(1):85-94. Epub 2016 Sep 26. PMID:
27672054
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Dysbiosis
Additional Keywords
:
Microbiota
[+]
Smoking may be a risk factor for pulmonary metastasis of colorectal cancer.
Jul 28, 2017
Click here to read the entire abstract
Pubmed Data
: Colorectal Dis. 2017 Jul 29. Epub 2017 Jul 29. PMID:
28755421
Article Published Date
: Jul 28, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
,
Smoking
Additional Keywords
:
Risk Factors
[+]
Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development.
Jun 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS Pathog. 2017 Jul ;13(7):e1006440. Epub 2017 Jul 13. PMID:
28704539
Article Published Date
: Jun 30, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Dysbiosis
Additional Keywords
:
Increased Risk
,
Microbiota
[+]
Sulforaphane has a novel chemopreventive mechanism in human colon cancer cells and prostate epithelial cells, namely the inhibition of histone deacetylase (HDAC). I
Feb 01, 2007
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2007 Feb;232(2):227-34. PMID:
17259330
Article Published Date
: Feb 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
,
Prostate Cancer
,
Prostate Cancer: Prevention
Pharmacological Actions
:
Chemopreventive
,
Enzyme Inhibitors
,
Histone deacetylase inhibitor
[+]
Supplementation with Brazil nuts and green tea extract regulates targeted biomarkers related to colorectal cancer risk in humans.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2016 Dec ;116(11):1901-1911. Epub 2016 Dec 7. PMID:
27923410
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Brazil nuts
,
Green Tea
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
Additional Keywords
:
Plant Extracts
[+]
Supplementation with fish oil for the first 9 weeks of chemotherapy may contribute to delay in tumor progression in colorectal patients.
Dec 22, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Dec 23:1-7. Epub 2015 Dec 23. PMID:
26700096
Article Published Date
: Dec 22, 2015
Study Type
: Human Study
Additional Links
Substances
:
Fish Oil
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
[+]
The combination of curcumin and quercetin appears to reduce the number and size of ileal and rectal adenomas in patients with Familialadenomatous polyposis without appreciable toxicity.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: Clin Gastroenterol Hepatol. 2006 Aug;4(8):1035-8. Epub 2006 Jun 6. PMID:
16757216
Article Published Date
: Aug 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
,
Quercetin
Diseases
:
Colon Polyps
,
Colorectal Cancer
,
Familial Adenomatous Polyposis
,
Gastrointestinal polyps
Pharmacological Actions
:
Antineoplastic Agents
,
Antioxidants
[+]
The consumption of apples is inversely related to the risk of colorectal cancer.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Rev Environ Health. 2009 Jan-Mar;24(1):59-74. PMID:
19476292
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Apples
Diseases
:
Colon Cancer
,
Colorectal Cancer
[+]
The consumption of soy foods may reduce the risk of colorectal cancer in postmenopausal women.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2009 Feb;89(2):577-83. Epub 2008 Dec 10. PMID:
19073792
Article Published Date
: Feb 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Soy
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
The effect of biofeedback training on intestinal function among patients with middle and low rectal cancer.
Oct 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Transl Med. 2019 Nov ;7(21):605. PMID:
32047766
Article Published Date
: Oct 31, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Rectal Cancer
Therapeutic Actions
:
Biofeedback
Additional Keywords
:
Risk Reduction
[+]
The present RCT provides evidence that serum from patients taking the extract showed cytotoxicity against human colorectal cancer cell lines.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asia Pac J Clin Nutr. 2017 ;26(4):606-612. PMID:
28582808
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Graviola
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Apoptotic
,
Cytotoxic
[+]
The regular consumption of apples reduces colorectal cancer risk.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2009 Mar;104(3):262-71. Epub 2009 Jan 20. PMID:
19926998
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Apples
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
The regular consumption of decaffeinated coffee is associated wtih a reduced incidence of rectal cancer.
Nov 01, 2006
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2006 Nov;13(9-10):624-9. Epub 2005 Nov 2. PMID:
15713963
Article Published Date
: Nov 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Coffee
Diseases
:
Colorectal Cancer
Additional Keywords
:
Risk Reduction
[+]
The results of this study suggests that gut microbiota could be related to colorectal cancer prevention and development.
Nov 03, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Nov 4. Epub 2015 Nov 4. PMID:
26549775
Article Published Date
: Nov 03, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Additional Keywords
:
Microbiota
,
Risk Factors
[+]
There is a statistically significant association between statin intake and colorectal cancer risk.
Oct 21, 2012
Click here to read the entire abstract
Pubmed Data
: BMC Cancer. 2012 Oct 22 ;12(1):487. Epub 2012 Oct 22. PMID:
23088590
Article Published Date
: Oct 21, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Carcinogenic
[+]
These findings suggest that coffee consumption might impact the prevention of CRC, especially distal colon cancer.
Jul 14, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2017 Jul 15 ;141(2):298-308. Epub 2017 May 8. PMID:
28425092
Article Published Date
: Jul 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Coffee
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
These findings suggest that diet-related inflammation might contribute to development of colorectal cancer.
Aug 29, 2017
Click here to read the entire abstract
Pubmed Data
: Gastroenterology. 2017 Aug 30. Epub 2017 Aug 30. PMID:
28865736
Article Published Date
: Aug 29, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Inflammation
Additional Keywords
:
Risk Factors
[+]
These results suggest a potential role of oral health in colorectal carcinogenesis.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2017 Feb 1 ;140(3):646-652. Epub 2016 Nov 23. PMID:
27778343
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Periodontal Diseases
Additional Keywords
:
Risk Factors
[+]
These results suggest that meat intake and NSAID use affect the same carcinogenic mechanisms.
Mar 04, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Mar 5 ;20(5). Epub 2019 Mar 5. PMID:
30841568
Article Published Date
: Mar 04, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Additional Keywords
:
Risk Factors
Problem Substances
:
Meat
,
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
These results support an association between red and processed meat and colorectal cancer risk.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Epidemiol. 2017 May ;32(5):409-418. Epub 2017 Jun 23. PMID:
28646407
Article Published Date
: Apr 30, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
Additional Keywords
:
Risk Factors
Problem Substances
:
Meat
[+]
This study provides support for the use of 25-hydroxyvitamin D as a new predictor of outcome for colorectal liver metastases patients.
Feb 19, 2016
Click here to read the entire abstract
Pubmed Data
: J Gastroenterol Hepatol. 2016 Feb 20. Epub 2016 Feb 20. PMID:
26896637
Article Published Date
: Feb 19, 2016
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Additional Keywords
:
25-hydroxyvitamin D
[+]
This study reports that a meat and sugary dietary pattern increased, while a plant-based dietary pattern decreased the risk of colorectal cancer.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr J. 2015 ;14:8. Epub 2015 Jan 15. PMID:
25592002
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Diseases
:
Colon Cancer
,
Colorectal Cancer
Additional Keywords
:
Risk Factors
Problem Substances
:
Meat
,
Sugar Sweetened Beverages
[+]
This study supports the hypothesis that black raspberries might be beneficial to colorectal cancer patients through the regulation of multiple metabolites.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2015 Aug ;8(8):743-50. Epub 2015 Jun 8. PMID:
26054356
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Black Raspberry
Diseases
:
Colorectal Cancer
Additional Keywords
:
Metabolites
[+]
Total vegetable intake, total fruit intake, and lettuce, apple, and banana consumption is associated with a reduced risk for colorectal cancer.
Jan 01, 1996
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 1996;25(3):297-304. PMID:
8771572
Article Published Date
: Jan 01, 1996
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Banana
,
Fruit: All
,
Lettuce
,
Vegetables: All
Diseases
:
Colon Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Turkey tail (Coriolus versicolor) mushroom contains compounds which improved quality of life, provided substantial pain relief, and enhanced immune status in patients with cancers of the stomach, colon-rectum, esophagus, nasopharynx, lung (non-small cell
Feb 01, 2000
Click here to read the entire abstract
Pubmed Data
: Altern Med Rev. 2000 Feb;5(1):4-27. PMID:
10696116
Article Published Date
: Feb 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Turkey Tail Mushroom
Diseases
:
Breast Cancer
,
Colorectal Cancer
,
Esophageal Cancer
,
Lung Cancer
,
Nasopharyngeal Cancer
,
Stomach Cancer
Additional Keywords
:
Plant Extracts
[+]
Vegetables and fruits intake from various color groups may protect against colorectal cancer.
Apr 13, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2017 Apr 14 ;23(14):2527-2538. PMID:
28465637
Article Published Date
: Apr 13, 2017
Study Type
: Human Study
Additional Links
Substances
:
Fruit: All
,
Vegetables: All
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Vitamin B-6 deficiency could be associated with a clear increase in colorectal cancer tumor progression.
Mar 07, 2017
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2017 Mar 8. Epub 2017 Mar 8. PMID:
28275126
Article Published Date
: Mar 07, 2017
Study Type
: Human Study
Additional Links
Substances
:
Vitamin B-6
Diseases
:
Colorectal Cancer
,
Vitamin B6 Depletion
Pharmacological Actions
:
Chemotherapeutic
Additional Keywords
:
Risk Factors
,
Risk Reduction
[+]
Vitamin D appears to reduce the risk of colorectal cancer.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila Pa). 2009 Mar;2(3):213-23. Epub 2009 Mar 3. PMID:
19258546
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Women who exercised after diagnosis of nonmetastatic colorectal had reduced colorectal cancer-specfic mortality of between 52% and 61% between 49% and 57% reduction in all-cause mortality.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Clin Oncol. 2006 Aug 1 ;24(22):3527-34. Epub 2006 Jul 5. PMID:
16822844
Article Published Date
: Aug 01, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Colorectal Cancer
,
Mortality: All-Cause
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Chemopreventive
[+]
Yogurt consumption was associated with a reduced risk of proximal colon cancer with a long latency period.
Oct 05, 2020
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2020 Oct 6. Epub 2020 Oct 6. PMID:
33022694
Article Published Date
: Oct 05, 2020
Study Type
: Human Study
Additional Links
Substances
:
Yoghurt
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
6-gingerol a component of ginger is extensively metabolized in H-1299 human lung cancer cells.
Nov 13, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Agric Food Chem. 2012 Nov 14 ;60(45):11372-7. Epub 2012 Nov 6. PMID:
23066935
Article Published Date
: Nov 13, 2012
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginger
Diseases
:
Cancers
,
Carcinoma: Non-Small-Cell Lung
,
Colon Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Biotransformation
,
Plant Extracts
[+]
Angelica sinesis extracts display antiproliferative, anti-inflammatory, anti-mutagenic effects in vitro.
Mar 01, 2018
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2018 Mar ;43(6):1235-1240. PMID:
29676134
Article Published Date
: Mar 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Dong Quai
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-cancer
,
Anti-Inflammatory Agents
,
Antimutagenic Agents
,
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
Anti-cancer activity of bromelain nanoparticles by oral administration.
Nov 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Biomed Nanotechnol. 2014 Dec ;10(12):3558-75. PMID:
26000370
Article Published Date
: Nov 30, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Bromelain
Diseases
:
Breast Cancer
,
Cancers: All
,
Cervical Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
[+]
Calebin A potentiates the effect of 5-FU and TNF-β against human colorectal cancer cells.
Mar 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2020 Mar 31 ;21(7). Epub 2020 Mar 31. PMID:
32244288
Article Published Date
: Mar 30, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Turmeric
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemosensitizer
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
[+]
chokeberry juice inhibited Caco-2 cell proliferation by causing G(2)/M cell cycle arrest.
Mar 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2007 Apr ;18(4):259-71. Epub 2006 Jul 24. PMID:
16860979
Article Published Date
: Mar 31, 2007
Study Type
: Human In Vitro
Additional Links
Substances
:
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Chemopreventive
[+]
Endocannabinoid and ceramide levels are altered in patients with colorectal cancer.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Jul ;34(1):447-54. Epub 2015 May 12. PMID:
25975960
Article Published Date
: Jun 30, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Endocannabinoids
Diseases
:
Colorectal Cancer
Additional Keywords
:
Cannabinoid Receptors
,
Endocannabinoid System
[+]
Findings suggest that Plantago ovata husk could be a potentially useful adjuvant in chemotherapy for colorectal cancer.
Jun 01, 2012
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2012 Jun ;107(11):1591-602. Epub 2011 Sep 29. PMID:
22018732
Article Published Date
: Jun 01, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Plantago major
Diseases
:
Colorectal Cancer
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Dec 24 ;194:83-90. Epub 2016 Aug 23. PMID:
27566200
Article Published Date
: Dec 23, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Kahweol inhibits colorectal tumor cell growth by promoting apoptosis and suppressing HSP70 expression.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomol Ther (Seoul). 2015 Mar ;23(2):128-33. Epub 2015 Mar 1. PMID:
25767680
Article Published Date
: Feb 28, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Kahweol
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Apoptotic
,
Bcl-2 protein down-regulation
,
Caspase-3 Activation
,
Heat Shock Protein Down-Regulation
[+]
Morus alba flavonoid extract and doxorubicin induce a dose dependent cell death in HT-29 cell line.
Mar 30, 2016
Click here to read the entire abstract
Pubmed Data
: Cell Mol Biol (Noisy-le-grand). 2016 Mar 31 ;62(3):72-7. Epub 2016 Mar 31. PMID:
27064876
Article Published Date
: Mar 30, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
White Mulberry
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
,
COLON CANCER
,
Dose Response
,
Plant Extracts
,
White Mulberry
[+]
Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.
May 08, 2012
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2012 May 8. Epub 2012 May 8. PMID:
22566066
Article Published Date
: May 08, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Catechin
,
EGCG (Epigallocatechin gallate)
,
Ginseng
,
Green Tea
,
Panaxadiol
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemosensitizer
Additional Keywords
:
Natural Substance Synergy
[+]
Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Intest Res. 2017 Apr ;15(2):174-181. Epub 2017 Apr 27. PMID:
28522946
Article Published Date
: Mar 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Feverfew
,
Parthenolide
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Probiotic lactobacillus had inhibitory effects of on the growth of human colonic carcinoma cell line HT-29.
Jan 09, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2017 Jan 10 ;22(1). Epub 2017 Jan 10. PMID:
28075415
Article Published Date
: Jan 09, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Lactobacillus probiotics
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Chemopreventive
[+]
Silybin counteracts doxorubicin resistance by inhibiting GLUT1 expression.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2018 Jan ;124:42-48. Epub 2017 Oct 12. PMID:
29031537
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Silibinin
Diseases
:
Cancers: Drug Resistant
,
Cancers: Multi-Drug Resistant
,
Colon Cancer
Pharmacological Actions
:
Chemosensitizer
,
Glucose transporter-1 (GLUT1) expression down-regulation
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.
Jan 01, 2018
Click here to read the entire abstract
Pubmed Data
: Cells Tissues Organs. 2018 ;206(1-2):46-53. Epub 2018 Jul 24. PMID:
30041241
Article Published Date
: Jan 01, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-cancer
,
Anti-metastatic
,
Anti-Proliferative
,
Cyclooxygenase 2 Inhibitors
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation
Additional Keywords
:
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
[+]
Sulforaphane inhibits Wnt/β-catenin signaling in colorectal cancer cells, supressing proliferation and inducing cell death.
Sep 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2018 Sep 21 ;9(74):33982-33994. Epub 2018 Sep 21. PMID:
30338040
Article Published Date
: Sep 21, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Wnt/β-catenin pathway down-regulation
Additional Keywords
:
Anti-cancer
[+]
Sulforaphane regulates xenobiotic metabolism phase II and III enzymes differently in colorectal cancer and untransformed epithelial colon cells.
Oct 31, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2016 Nov-Dec;68(8):1338-1348. Epub 2016 Aug 16. PMID:
27636860
Article Published Date
: Oct 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Colon Cancer
Pharmacological Actions
:
Cytoprotective
,
Nrf2 activation
Additional Keywords
:
Gene Expression Regulation
,
Selective Cytotoxicity
[+]
The apple polyphenol phloretin inhibits colorectal cancer cell growth.
Sep 13, 2016
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2016 Sep 14 ;64(36):6826-37. Epub 2016 Sep 2. PMID:
27538679
Article Published Date
: Sep 13, 2016
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Apple Polyphenols
,
Phloretin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Tumor Suppressor Protein p53 Upregulation
[+]
The present study shows that lichen compounds demonstrated strong antioxidant, antimicrobial, and anticancer properties.
Oct 14, 2012
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2012 Oct 15 ;19(13):1166-72. Epub 2012 Aug 22. PMID:
22921748
Article Published Date
: Oct 14, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Lichens
Diseases
:
Colon Cancer
,
Melanoma
Pharmacological Actions
:
Antimicrobial
,
Antioxidants
,
Chemopreventive
Additional Keywords
:
Antimicrobial
,
Antioxidants
,
Chemopreventive
,
COLON CANCER
,
Lichens
,
melanoma
[+]
The present work emphasizes the potential of berries in chemoprevention, especially CRC chemoprevention.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Oxid Med Cell Longev. 2015;2015:154164. Epub 2015 Jun 9. PMID:
26180579
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Black Currant
,
Blackberry
,
Blueberry
,
Cranberry
,
Indian Gooseberry
,
Lingonberry
,
Raspberry
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Apoptotic
,
Caspase-8 activation
,
Chemopreventive
Additional Keywords
:
Dietary Concentrations
,
Growing Your Own Food
,
Procyanidins
[+]
These results increase knowledge of the effect of gastrointestinal digestion on the biological effect of honey against colorectal cancer.
Jan 09, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Antioxidants (Basel). 2020 Jan 10 ;9(1). Epub 2020 Jan 10. PMID:
31936782
Article Published Date
: Jan 09, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Manuka Honey
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
These results provide important new data for ellagic acid in anti-colorectal carcinoma research.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2017 Feb ;50(2):613-621. Epub 2017 Jan 5. PMID:
28101576
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Gene Expression Regulation
[+]
verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Genom Data. 2015 Sep 1 ;5:189-191. PMID:
26309812
Article Published Date
: Aug 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Mushrooms: All
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Cell cycle arrest
,
Chemotherapeutic
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
,
Epigenetic Modification In Cancer
,
Gene Expression Regulation
[+]
Wogonin decreased the expression of glycolysis-related proteins, glucose uptake and lactate generation in a dose-dependent manner.
Jan 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2014 Feb ;53 Suppl 1:E107-18. Epub 2013 Jun 13. PMID:
23761018
Article Published Date
: Jan 31, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Wogonin
Diseases
:
Cancers: Drug Resistant
,
Cancers: Multi-Drug Resistant
,
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
PI3K/Akt/signaling suppression
Additional Keywords
:
Cancer Glycolysis
,
Resistance Reversal
[+]
γ-tocotrienol and 6-gingerol when used in combination act synergistically increasing cytotoxicity and apoptosis in cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Molecules. 2015 ;20(6):10280-97. Epub 2015 Jun 3. PMID:
26046324
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Gingerol
,
Tocotrienol: Gamma
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Natural Substance Synergy
[+]
Spontaneous regression of mismatch repair-deficient colorectal cancers: Case series.
May 15, 2020
Click here to read the entire abstract
Pubmed Data
: Dig Endosc. 2020 May 16. Epub 2020 May 16. PMID:
32416608
Article Published Date
: May 15, 2020
Study Type
: Human: Case Report
Additional Links
Diseases
:
Colorectal Cancer
Additional Keywords
:
Spontaneous Tumor Regression
[+]
"Phase I clinical studies of antineoplaston A3 injections."
Jan 01, 1987
Click here to read the entire abstract
Pubmed Data
: Drugs Exp Clin Res. 1987 ;13 Suppl 1:17-29. PMID:
3569012
Article Published Date
: Jan 01, 1987
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplaston A3
Diseases
:
Bladder Cancer
,
Colon Cancer
,
Epithelioma
,
Prostate Cancer
Pharmacological Actions
:
Antineoplastic Agents
[+]
"Phase I clinical studies of antineoplaston A5 injections."
Jan 01, 1987
Click here to read the entire abstract
Pubmed Data
: Drugs Exp Clin Res. 1987 ;13 Suppl 1:37-43. PMID:
3569014
Article Published Date
: Jan 01, 1987
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplaston A5
Diseases
:
Bladder Cancer
,
Breast Cancer
,
Colorectal Cancer
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Chemopreventive
[+]
Case report: long-term survival following treatment with antineoplastons for colon cancer with unresectable multiple liver metastases.
Jan 01, 2003
Click here to read the entire abstract
Pubmed Data
: Surg Today. 2003 ;33(6):448-53. PMID:
12768372
Article Published Date
: Jan 01, 2003
Study Type
: Human: Case Report
Additional Links
Substances
:
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
Diseases
:
Colon Cancer
,
Liver Cancer
,
Liver Cancer: Metastatic
,
Liver Metastasis From Colon Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Spontaneous regression of advanced transverse colon cancer with remaining lymph node metastasis.
May 10, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Surg Case Rep. 2020 May 11 ;6(1):100. Epub 2020 May 11. PMID:
32394212
Article Published Date
: May 10, 2020
Study Type
: Human: Case Report
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Spontaneous Tumor Regression
[+]
Spontaneous regression of colorectal liver metastasis.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Clin J Gastroenterol. 2018 Aug ;11(4):263-267. Epub 2018 Mar 15. PMID:
29546568
Article Published Date
: Jul 31, 2018
Study Type
: Human: Case Report
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Spontaneous Regression
[+]
Spontaneous regression of transverse colon cancer with high-frequency microsatellite instability.
Jan 14, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Surg Oncol. 2019 Jan 15 ;17(1):19. Epub 2019 Jan 15. PMID:
30646898
Article Published Date
: Jan 14, 2019
Study Type
: Human: Case Report, Review
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Spontaneous Tumor Regression
[+]
Spontaneous regression of transverse colon cancer: a case report.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Surg Case Rep. 2017 Dec ;3(1):65. Epub 2017 May 10. PMID:
28488173
Article Published Date
: Nov 30, 2017
Study Type
: Human: Case Report
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Spontaneous Regression
[+]
This is the first report showing complete regression of a colon adenoma after intratumoural injection with Viscum album extract.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Gastrointestin Liver Dis. 2014 Dec ;23(4):449-52. PMID:
25532007
Article Published Date
: Nov 30, 2014
Study Type
: Human: Case Report
Additional Links
Substances
:
Mistletoe
Diseases
:
Colon Cancer
,
Colon Polyps
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Disease Regression
[+]
Topical aloe vera for the treatment of cetuximab-related acneiform rash in colorectal cancer.
Jul 04, 2020
Click here to read the entire abstract
Pubmed Data
: J Oncol Pharm Pract. 2020 Jul 5:1078155220937751. Epub 2020 Jul 5. PMID:
32623964
Article Published Date
: Jul 04, 2020
Study Type
: Human: Case Report
Additional Links
Substances
:
Aloe Vera
Diseases
:
Chemotherapy and Radiation Toxicity
,
Colorectal Cancer
Pharmacological Actions
:
Chemoprotective Agents
Problem Substances
:
Cetuximab
[+]
Useless and dangerous—fine needle aspiration of hepatic colorectal metastases
Feb 27, 2004
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMJ. 2004 Feb 28 ;328(7438):507-8. PMID:
14988193
Article Published Date
: Feb 27, 2004
Study Type
: Human: Case Report
Additional Links
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
,
Liver Cancer
,
Liver Metastasis From Colon Cancer
Anti Therapeutic Actions
:
Fine Needle Aspiration
[+]
Berberin inhibited colorectal cancer invasion and metastasis via down regulation of COX-2/PGE2- JAK2/STAT3 signaling pathway.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(5):e0123478. Epub 2015 May 8. PMID:
25954974
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Prostaglandin PGE2 downregulation
[+]
Emodin reverses 5-Fu resistance in human colorectal cancer via downregulation of PI3K/Akt signaling pathway.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2020 ;12(5):1851-1861. Epub 2020 May 15. PMID:
32509181
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Emodin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Chemosensitizer
[+]
Preventive effects of Korean red ginseng on experimentally induced colitis and colon carcinogenesis.
Apr 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Tradit Complement Med. 2020 May ;10(3):198-206. Epub 2020 Apr 25. PMID:
32670814
Article Published Date
: Apr 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Colitis
,
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
The inhibitory effect of oridonin on colon cancer was mediated by deactivation of TGF-β1/Smads-PAI-1 signaling pathway in vitro and vivo.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2019 ;12:7467-7476. Epub 2019 Sep 11. PMID:
31686852
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Oridonin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Transforming growth factor beta (TGF-β) inhibitor
Additional Keywords
:
Dose Response
[+]
"Antineoplaston AS2-1 showed an antimetastatic effect against post-operative lung metastases from colon cancer through G1 cell arrest and the subsequent induction of apoptosis."
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2005 Mar ;13(3):389-95. PMID:
15706406
Article Published Date
: Mar 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Antineoplaston AS2-1 (4:1 mixture of phenylacetic acid and phenylacetylglutamine)
Diseases
:
Cancer Metastasis
,
Colon Cancer
,
Lung Cancer: Metastatic
,
Post-Operative Lung Metastasis of Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cell cycle arrest
[+]
"Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo.
Dec 21, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Dec 22 ;58(24):12999-3005. Epub 2010 Nov 17. PMID:
21082859
Article Published Date
: Dec 21, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Capsaicin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
[+]
"Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo."
Dec 21, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Dec 22 ;58(24):12999-3005. Epub 2010 Nov 17. PMID:
21082859
Article Published Date
: Dec 21, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Capsaicin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
[+]
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside may be a promising natural lead compound for treating early phases of colorectal cancer.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2017 ;2017:3634915. Epub 2017 Nov 7. PMID:
29238715
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2019 Feb 1 ;448:20-30. Epub 2019 Feb 1. PMID:
30716361
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Colon Cancer
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
[+]
5-FU and thymoquinone combination therapy resulted in a more significant reduction on AOM-induced colorectal tumors.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2016 ;10:2239-53. Epub 2016 Jul 11. PMID:
27468227
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
,
Wnt/β-catenin signaling pathway modulation
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
,
Gene Expression Regulation
[+]
6-gingerol delays tumorigenesis in benzo[a]pyrene and dextran sulphate sodium-induced colorectal cancer.
Jun 04, 2020
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2020 Jun 5 ;142:111483. Epub 2020 Jun 5. PMID:
32512025
Article Published Date
: Jun 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Benzo[a]pyrene-induced Toxicity
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Problem Substances
:
Benzo(a)pyrene
[+]
A combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Jan;48(1):390-5. Epub 2009 Oct 25. PMID:
19861145
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Curcumin
,
Green Tea
Diseases
:
Colon Cancer
,
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Drug Synergy
[+]
A combined mixture of medicinal mushrooms and P. ginseng root extracts could be an adjuvant treatment in human colorectal cancer.
Aug 31, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Sep ;38(3):1597-1604. Epub 2017 Jul 7. PMID:
28714027
Article Published Date
: Aug 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Medicinal Mushrooms
,
Panax Ginseng
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
A compound found exclusively in irradiated dietary fats may promote colon carcinogenesis in animals treated with a chemical carcinogen.
Jan 01, 2002
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2002;44(2):189-91. PMID:
12734067
Article Published Date
: Jan 01, 2002
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
Additional Keywords
:
Gamma Irradiation
Anti Therapeutic Actions
:
Gamma Irradiation: "Cold Pasteurization"
[+]
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer.
Mar 26, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2019 Mar 27. Epub 2019 Mar 27. PMID:
30919084
Article Published Date
: Mar 26, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
A grape powder attenuates colonic inflammation, inhibits colitis-associated colorectal cancer development.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID:
31224334
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Grape
Diseases
:
Colitis
,
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Gastrointestinal Agents
[+]
A high vitamin D diet reduced proliferation, increased differentiation and apoptosis, and in parallel, upregulated mRNA expression of the calcium-sensing receptor in the colon of mice.
Mar 06, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Steroid Biochem Mol Biol. 2015 Mar 7. Epub 2015 Mar 7. PMID:
25758239
Article Published Date
: Mar 06, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Calcium
,
Vitamin D
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
[+]
A holistic view of berberine inhibiting intestinal carcinogenesis.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Front Immunol. 2020 ;11:588079. Epub 2020 Sep 24. PMID:
33072135
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
A mixture of phytochemicals naturally present in foods represents a plausible chemopreventive agent for colorectal cancer.
May 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2011 Jun ;4(6):907-15. Epub 2011 Mar 7. PMID:
21383028
Article Published Date
: May 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
,
Apples
,
Flavonoids
Diseases
:
Colon Polyps
,
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
Additional Keywords
:
Dietary Concentrations
[+]
A red yeast rice extract inhibits the proliferation of colorectal cancer cells.
Mar 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2008 Mar;11(1):91-8. PMID:
20356949
Article Published Date
: Mar 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Red Yeast Rice
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Plant Extracts
[+]
A sucrose-rich diet induces mutations in the rat colon.
Aug 01, 2002
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2002 Aug 1;62(15):4339-45. PMID:
12154038
Article Published Date
: Aug 01, 2002
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
,
DNA damage
,
Oxidative Stress
Problem Substances
:
Sucrose
[+]
A water extract of broken spores of G. lucidum possesses chemopreventive potential in colorectal cancer.
Apr 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2017 May ;50(5):1541-1554. Epub 2017 Mar 29. PMID:
28358412
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
A water extract of sea cucumber revealed remarkable anti-proliferative effect on CT26 tumor cells.
Mar 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2016 Apr ;19(4):358-65. PMID:
27279978
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sea Cucumber
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
A water-extracted polysaccharide from Lentinus edodes exerts direct antitumor effects by inducing apoptosis in colon cancer cells.
Nov 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Nov 21. Epub 2016 Nov 21. PMID:
27888812
Article Published Date
: Nov 20, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Shiitake Mushroom
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bax/Bcl2 ratio: Increase
,
Caspase-3 Activation
,
NF-kappaB Inhibitor
Additional Keywords
:
Polysaccharides
[+]
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice.
Nov 01, 2001
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2001 Nov;22(11):1871-5. PMID:
11698351
Article Published Date
: Nov 01, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Folic Acid
,
Methionine
,
Vitamin B-12
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
Anti Therapeutic Actions
:
Western Diet
[+]
Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.
Mar 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut Liver. 2017 Mar 15 ;11(2):243-252. PMID:
27965474
Article Published Date
: Mar 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Acai
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acute addition of Vitamin C to the basolateral membrane maintains low intracellular pH for a longer period which could halt or prevent tumor formation.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2017 ;44(1):377-387. Epub 2017 Nov 13. PMID:
29132138
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Adenosine and P. distasonis have previously been shown to be anti-inflammatory in the colon and we postulate their reduction could promote tumorigenesis by de-repressing inflammation.
Jan 31, 1973
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut. 1973 Feb ;14(2):89-93. PMID:
PMC4540493
Article Published Date
: Jan 31, 1973
Study Type
: Animal Study
Additional Links
Diseases
:
Colon Cancer
,
Inflammation
,
Obesity
Additional Keywords
:
Microbiome
,
Microbiota
,
Risk Factors
[+]
Adlay bran ethanolic extract suppressed 1,2-dimethylhydrazine-indued preneoplastic lesions of the colon.
Jul 13, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Jul 14 ;58(13):7616-23. PMID:
20536243
Article Published Date
: Jul 13, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Adlay
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Adlay
,
Anti-Inflammatory Agents
,
Chemopreventive
,
COLON CANCER
,
Cyclooxygenase 2 Inhibitors
,
Plant Extracts
[+]
Age may play a significant role in the efficacy of chemoprevention of colon cancer by curcumin.
Jan 01, 2004
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2004;48(1):37-43. PMID:
15203376
Article Published Date
: Jan 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Enzyme Inhibitors
[+]
Aged garlic extract suppressed the proliferative activity in adenoma and adenocarcinoma lesions, but showed no effect on normal colon mucosa.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Mar ;33(3):1131-40. Epub 2014 Dec 30. PMID:
25573280
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Chemopreventive
,
NF-kappaB Inhibitor
Additional Keywords
:
Selective Antiproliferation
[+]
Allicin inhibits mouse colorectal tumorigenesis through suppressing the activation of STAT3 signaling pathway.
Apr 22, 2018
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2018 Apr 23:1-4. Epub 2018 Apr 23. PMID:
29683343
Article Published Date
: Apr 22, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
,
STAT3 Activation
[+]
Aloe vera gel could suppress colitis-related colon carcinogenesis.
Sep 29, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Sep 30 ;40:428-435. Epub 2016 Aug 30. PMID:
27697726
Article Published Date
: Sep 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Cell cycle arrest
,
Chemopreventive
,
NF-kappaB Inhibitor
[+]
Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS-treated mice.
Sep 16, 2020
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2020 Sep 17. Epub 2020 Sep 17. PMID:
32940665
Article Published Date
: Sep 16, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Fucoxanthin
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Gastrointestinal Agents
[+]
Alternating consumption of β-glucan and quercetin reduces mortality in mice with colorectal cancer.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Sci Nutr. 2019 Oct ;7(10):3273-3285. Epub 2019 Sep 4. PMID:
31660141
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Beta-glucan
,
Quercetin
Diseases
:
Cancer Mortality
,
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemotherapeutic
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Gene Expression Regulation
[+]
American ginseng exerts the chemopreventive effects by anti-inflammatory and antioxidant mechanisms.
Aug 06, 2015
Click here to read the entire abstract
Pubmed Data
: J Proteome Res. 2015 Aug 7 ;14(8):3336-47. Epub 2015 Jul 10. PMID:
26136108
Article Published Date
: Aug 06, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (American)
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemopreventive
[+]
An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer.
Jun 04, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2017 Jun 5 ;804:13-20. Epub 2017 Apr 5. PMID:
28389232
Article Published Date
: Jun 04, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apple
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemosensitizer
Additional Keywords
:
Chemothapeutic Synergy: 5-flourouracil
[+]
An aqueous extract of fermented barley with Lactobacillus plantarum dy-1 had a greater apoptotic rate than 5-fluorouracil.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Environ Sci. 2017 Jan ;30(1):10-21. PMID:
28245895
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Barley
,
Fermented Foods and Beverages
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
An extract of Curcuma purpurascens suppressed the proliferation of HT-29 colon cancer cells and triggered the induction of apoptosis through mitochondrial-dependent pathway.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15:15. Epub 2015 Feb 5. PMID:
25652758
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcuma Purpurascens
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-9 Activation
Additional Keywords
:
Dose Response
[+]
Annatto has possible chemopreventive effects through modulation of the cryptal cell proliferation but not at the initiation stage of colon carcinogenesis.
Apr 03, 2005
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2005 Apr 4 ;582(1-2):146-54. PMID:
15781219
Article Published Date
: Apr 03, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Achiote
Diseases
:
Colon Cancer
,
DNA damage
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
Additional Keywords
:
Plant Extracts
[+]
Anthocyanin containing purple fleshed potatoes suppressed colon tumorigenesis via elimination of colon cancer stem cells.
Aug 13, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2015 Aug 14. Epub 2015 Aug 14. PMID:
26383537
Article Published Date
: Aug 13, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Potato: Pigmented
Diseases
:
Colon Cancer
,
Colon Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Wnt/β-catenin pathway down-regulation
Additional Keywords
:
Cancer Stem Cells
,
Natural Substances Versus Drugs
,
Plant Extracts
Problem Substances
:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
Anthocyanin enriched sweet potatoes may protect against colorectal cancer by inducing cell-cycle arrest, antiproliferative, and apoptotic mechanisms.
Oct 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Nutr Food Res. 2013 Nov ;57(11):1908-17. Epub 2013 Jun 19. PMID:
23784800
Article Published Date
: Oct 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Fiber
,
Sweet Potato: Purple
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antineoplastic Agents
,
Antioxidants
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
Additional Keywords
:
Plant Extracts
,
Risk Reduction
[+]
Anthocyanins prevented the formation and growth of colorectal cancer in mice.
May 11, 2017
Click here to read the entire abstract
Pubmed Data
: Digestion. 2017 May 12 ;95(4):275-280. Epub 2017 May 12. PMID:
28494451
Article Published Date
: May 11, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemopreventive
[+]
Anthocyanins promoted colorectal Cancer cells apoptosis and inhibited colon cancer growth of xenografted tumors.
Jan 10, 2019
Click here to read the entire abstract
Pubmed Data
: Curr Pharm Des. 2019 12 11. Epub 2019 Dec 11. PMID:
31830892
Article Published Date
: Jan 10, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Anti-cancer effects of a neutral triterpene fraction from Ganoderma lucidum and its active constituents on SW620 human colorectal cancer cells.
Oct 13, 2019
Click here to read the entire abstract
Pubmed Data
: Anticancer Agents Med Chem. 2019 Oct 14. Epub 2019 Oct 14. PMID:
31749435
Article Published Date
: Oct 13, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Reishi Mushroom
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Anti-proliferative effect of leaf extracts of Eucalyptus citriodora against human cancer cells in vitro and in vivo.
Nov 30, 2012
Click here to read the entire abstract
Pubmed Data
: Indian J Biochem Biophys. 2012 Dec ;49(6):451-7. PMID:
23350280
Article Published Date
: Nov 30, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Eucalyptus
Diseases
:
Cervical Cancer
,
Colon Cancer
,
Liver Cancer
,
Lung Cancer
,
Neuroblastoma
,
Ovarian Cancer
,
Prostate Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2017 ;11:103-121. Epub 2016 Dec 28. PMID:
28096658
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curry Leaves
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Apoptotic
[+]
Apigenin could inhibit the growth of cisplatin-resistant colon cancer cells in vitro and in vivo.
Feb 28, 2019
Click here to read the entire abstract