Demyelinating Diseases

Name	AC	CK
Vitamin D	39	209
Cannabis	28	153
Cannabidiol	30	127
Delta-tetrahydrocannabinol (THC)	16	107
Cannabinoids	23	85
Vitamin E	8	54
Vitamin B-12	8	47
Coenzyme Q10	6	43
Curcumin	18	42
EGCG (Epigallocatechin gallate)	8	28
Probiotics	9	27
Testosterone	5	25
Cannabinoids: Synthetic	5	24
Melatonin	11	24
Omega-3 Fatty Acids	3	21
Vitamin B12: methylcobalamin	3	21
B-complex	1	20
Silibinin	2	20
Progesterone	6	18
Resveratrol	12	17
Polyunsaturated Fatty Acids (PUFAs)	4	16
Alpha-Lipoic Acid	5	15
Evening Primrose Oil	3	14
Antioxidant formulas	3	13
Coconut Oil	2	12
Estriol	3	12
Olive	3	12
Crocin	2	11
Estradiol (E(2))	7	11
Folic Acid	2	11
Glutathione	2	11
Vitamin A	2	11
Vitamin B-6	2	11
Bifidobacterium Bifidum	1	10
Bifidobacterium Infantis	1	10
Cocoa	1	10
Copper	1	10
Creatine	1	10
Fruit: All	1	10
Lactobacillus Acidophilus	1	10
Lactobacillus casei	1	10
Lactobacillus fermentum	1	10
Marijuana	1	10
Olive Oil	1	10
Phosphatidylethanolamine	1	10
Phosphatidylserine	1	10
Selenium	1	10
Superoxide dismutase	1	10
Thiamine (B-1)	1	10
Threonine	1	10
Vegetables: All	1	10
Vitamin K2	1	10
Whey	1	10
Zinc	1	10
Chrysin	3	8
Glycoaminoglycans	4	8
Insulin-like Growth Factor (IGF-1)	4	7
DHA (Docosahexaenoic Acid)	3	6
Oleanolic acid	3	6
St. Johns Wort	4	6
Apigenin	1	5
Catechin	1	5
Genistein	3	5
Luteolin	3	5
Nigella sativa (aka Black Seed)	3	5
Palmitoylethanolamide	2	5
Polyphenols	5	5
Tripterygium wilfordii	3	5
Astaxanthin	2	4
Astragaloside	3	4
Berberine	2	4
EPA (Eicosapentaenoic Acid)	2	4
Gamma-Linoleic Acid (GLA)	1	4
Ginger	3	4
Ginkgo biloba	3	4
Ginseng (Korean)	2	4
Hemp Seed	2	4
Hesperidin	2	4
Licorice	2	4
Saffron	3	4
Tanshinone IIA	2	4
Vitamin C	2	4
Arginine	2	3
Celery seed	2	3
Cinnamon	2	3
Gc protein-derived macrophage activating factor (GcMAF)	1	3
Ginsenosides	2	3
Magnesium	1	3
Moringa oleifera	2	3
Panax Ginseng	2	3
Penaeus Latisculatus (prawn)	2	3
Silica	1	3
Stilbenes	2	3
Sulforaphane	2	3
18β-Glycyrrhetinic Acid	1	2
5-HTP (5-Hydroxytryptophan)	1	2
6-Shogaol	1	2
Acetyl-l-carnitine	1	2
Aloe Vera	1	2
Amino Acids: Branched Chain	1	2
Arctigenin	1	2
Bee Venom	1	2
Beta-Caryophyllene	1	2
Beta-Elemene	1	2
Bixin	1	2
Blueberry	1	2
Burdock	1	2
Caprylic Acid	1	2
Celastrol	1	2
Chinese Herbal Formula: Qichu Fujin Recipe	1	2
Chinese Skullcap	1	2
EDTA (synthetic amino acid compound)	1	2
Ellagic Acid	1	2
Fiber	1	2
Fisetin	1	2
Flavonoids	2	2
Fucoidan	1	2
Galactooligosaccharides	1	2
Gingerol	1	2
Glucosamine	1	2
Glycyrrhizin	1	2
Goldenthread	1	2
Huperzine	1	2
Hydrogen Water	1	2
Isoliquiritigenin	1	2
Lactobacillus reuteri	1	2
Ligustrazine	1	2
Mangosteen	1	2
Myricetin	1	2
Naringenin	1	2
Neem	1	2
Nerve growth factor	1	2
Paeoniflorin	1	2
Parthenolide	1	2
Peony	1	2
Phytosterols	1	2
Piperine	1	2
Piperlongumine	1	2
Placenta Extract (or Stem Cells)	1	2
Prebiotics	1	2
Pyruvate	1	2
Red Wine Extract	2	2
Riboflavin (Vitamin B-2)	2	2
Rosemaric Acid	1	2
Rosemary	1	2
S-Adenosylmethionine (SAMe)	1	2
SAMe (S-adenosylmethionine)	2	2
Scolopendra subspinipes mutilans	1	2
Sesame Seed Oil	1	2
Sinomenine	1	2
Tarragon	1	2
Thyme	1	2
Thymus Extract	1	2
Triptolide	1	2
Vitamin E: alpha tocopherol	1	2
Wen Pi Tang	1	2
phytoestrogens	1	2
Andrographis	1	1
Ashwagandha	1	1
Beta Sitosterol	1	1
Broccoli	1	1
Caffeic acid phenethyl ester	1	1
Cannabichromene	1	1
Cannabigerol	1	1
Carnitine	1	1
Carnosol	1	1
Carvacrol	1	1
Cranberry	1	1
Diosgenin	1	1
Endocannabinoids	1	1
Eriodictyol	1	1
Fish Oil	1	1
Frankincense	1	1
Ginseng	1	1
Grape	1	1
Haritaki (Terminalia chebula)	1	1
Herbal Therapies (Unspecified in Abstracts)	1	1
Hydroxytyrosol	1	1
Kava Kava	1	1
Kombucha Tea	1	1
Lactobacillus probiotics	1	1
Lemon	1	1
Lion's Mane (Hericium Erinaceus)	1	1
Lysergic Acid Diethylamide (LSD)	1	1
Nordihydroguaiaretic acid (NDGA)	1	1
Pistachio nut	1	1
Psychedelics:All	1	1
Purslane	1	1
Safranal	1	1
Shikonin	1	1
Silymarin	1	1
Sodium benzoate (cinnamon metabolite)	1	1
Tauroursodeoxycholic acid	1	1
Thyroid hormones	1	1
Tibetan Herbal Formula: Padma 28	1	1
Turmeric	1	1
Tyrosol	1	1
Valerian	1	1
Vitamin B-3 (Niacin)	1	1
Vitamin B-5 (Pantothenic Acid)	1	1
Wine	1	1
acetyl-11-keto-beta-boswellic acid	1	1

Name	AC	CK
Pesticides	5	41
Gliadin	4	40
Lead	6	33
Statin Drugs	7	32
Fingolimod	4	31
Mercury	5	28
Gluten	5	23
Cow Milk	2	20
Dental Amalgams	1	20
Tobacco	2	20
Lyme's Disease (Borrelia burgdorferi)	5	15
Aluminum	6	11
Agricultural Chemicals	1	10
Butyrophilin	1	10
Candida species	1	10
Casein	1	10
Chlorpyrifos	1	10
Gadolinium	1	10
L-glutamic Acid	1	10
Monosodium Glutamate (MSG)	1	10
Nicotine	1	10
Persistent organic pollutants (POPs)	1	10
Infliximab	2	9
Simvastatin	4	7
Cadmium	2	6
Etanercept	1	6
Tumor Necrosis Factor (TNF) Inhibitor Drugs	1	6
Antibiotics	1	3
Bisphenol A	2	3
Fusidic acid	1	3
Industrial Copper (inorganic)	1	3
interferon beta-1b	1	3
Acetyl ethyl tetramethyl tetralin (AETT)	1	2
Carbonyl Iron	1	2
Concanavalin A	1	2
Freund adjuvant	1	2
Lectins	1	2
Lovastatin	2	2
Perfume: Synthetic	1	2
Thimerosal	1	2
Wheat Germ Agglutinin (WGA)	1	2
Barium	1	1
Bisphenol S	1	1
Epstein-Barr Virus	1	1
Excitotoxins	1	1
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	1
Sodium Selenite	1	1
Staphylococcus aureus: Enterotoxin A	1	1

Name	AC	CK
Sunlight exposure	10	111
Exercise	17	69
Pilates	3	40
Yoga	4	22
Dietary Modification: Mediterranean Diet	3	21
Ai-Chi Aquatic Exercise	2	20
Cryotherapy	2	20
Mindfullness Training	2	20
Stem Cell Related Therapy	4	15
Aquatic therapy	2	11
Dietary Modification: Low Carbohydrate/Ketogenic	2	11
Acupuncture	1	10
Biofeedback	1	10
Craniosacral Therapy	1	10
Deep Breathing	1	10
Exercise: Aerobic	1	10
Exercise: Cycling	1	10
Guided Imagery	1	10
Light Therapy	1	10
Loving	1	10
Massage/Therapeutic Touch	1	10
Meditation	1	10
Mediterranean diet	1	10
Ozone Therapy	1	10
Reflexology	1	10
Relaxation Therapy	1	10
Spiritual/Religious Practice	1	10
Tai Chi	1	10
Therapeutic Breathing	1	10
Ultrasound therapy	1	10
Whole-Body Vibration	1	10
Electroacupuncture	2	4
Exercise: Swimming	2	4
Fasting/Caloric Restriction	2	4
Laser Treatment: Low-Level	2	3
Exercise: Running	1	2
Hyperbaric Treatment	1	2
Intermittent Hypoxia (low oxygen)	1	2
Placentophagy	1	2
anti-inflammatory	1	2
antioxidant	1	2
neuro-protective	1	2
Dietary Modification: High-Fat/Low-Carbohydrate	1	1
Laser Treatment	1	1

Name	AC	CK
Vaccination: All	44	258
Vaccination: Hepatitis B	16	117
Vaccination: Influenza	10	63
Electromagnetic Field Harms	4	55
Electromagnetic Radiation	3	35
Vaccination: HPV (Gardasil)	4	32
Vaccination: Rabies	4	18
Vaccination: Diphtheria-Pertussis-Tetanus	3	13
Vaccination: Varicella (Chicken pox)	3	13
Vaccination: Yellow Fever	2	12
Cesarean Delivery	1	10
Vaccination: Mumps-Measles-Rubella (MMR)	4	10
Vaccination: Tetanus	2	3
Vaccination: Haemophilus Influenzae	1	2
Vaccination: Lyme disease	1	2
Vaccination: Rotavirus	1	2
Nocebo Effect	1	1

Problem Substances : Dental Amalgams, Mercury

Adverse Pharmacological Actions : Neurotoxic

[+]

In this meta-analysis, there was an observed increased risk of amytrophic lateral sclerosis in workers occupationally exposed to extremely low frequency electromagnetic fields. Feb 01, 2018

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Pubmed Data : Bioelectromagnetics. 2018 Feb ;39(2):156-163. Epub 2018 Jan 19. PMID: 29350413

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Pubmed Data : Mult Scler Relat Disord. 2019 Feb ;28:199-212. Epub 2019 Jan 3. PMID: 30623859

High-dose vitamin B supplementation for persistent visual deficit in multiple sclerosis.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Drug Discov Ther. 2020 ;14(3):122-128. PMID: 32669520

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur J Epidemiol. 2013 May ;28(5):433-44. Epub 2013 Mar 31. PMID: 23543123

Article Published Date : Apr 30, 2013

Study Type : Human Study

Additional Links

Diseases : Guillain-Barre Syndrome, H1N1 Infection

Anti Therapeutic Actions : Vaccination: Influenza

[+]

"Yellow fever vaccination and increased relapse rate in travelers with multiple sclerosis."Oct 01, 2011

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Pubmed Data : Arch Neurol. 2011 Oct ;68(10):1267-71. Epub 2011 Jun 13. PMID: 21670384

Antibody titers against EBV in MS patients rise after the onset of the disease and indicate that vitamin D3 supplementation could limit augmentation of these titers in MS patients.Feb 28, 2015

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Pubmed Data : Cell Immunol. 2015 Mar ;294(1):9-12. Epub 2015 Jan 28. PMID: 25666504

Article Published Date : Feb 28, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Epstein-Barr Virus Infections, Multiple Sclerosis, Vitamin D Deficiency

Pharmacological Actions : Immunomodulatory

Additional Keywords : Risk Factors, Risk Reduction

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Am J Epidemiol. 2009 May 15 ;169(10):1260-6. Epub 2009 Mar 27. PMID: 19329530

Article Published Date : May 15, 2009

Study Type : Human Study

Additional Links

Diseases : Multiple Sclerosis

Anti Therapeutic Actions : Vaccination: All, Vaccination: Varicella (Chicken pox)

[+]

Coenzyme Q10 levels as high as 3,000 mg a day are safe and well-tolerated in ALS patients. Dec 13, 2005

Pubmed Data : Muscle Nerve. 2006 Nov;34(5):586-94. PMID: 16881064

Article Published Date : Nov 01, 2006

Study Type : Human Study

Additional Links

Substances : Creatine

Diseases : Charcot-Marie-Tooth Disease

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[+]

Epstein-Barr virus infection may be associated with increased risk of multiple sclerosisDec 26, 2001

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Pubmed Data : JAMA. 2001 Dec 26;286(24):3083-8. PMID: 11754673

Article Published Date : Dec 26, 2001

Study Type : Human Study

Additional Links

Diseases : Epstein-Barr Virus Infections, Multiple Sclerosis

Additional Keywords : Diseases that are Linked

[+]

Evening primrose oil has beneficial effects on fatigue and quality of life in patients with multiple sclerosis.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neuropsychiatr Dis Treat. 2018 ;14:1505-1512. Epub 2018 Jun 12. PMID: 29928122

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Pubmed Data : Mult Scler. 2017 Mar 1:1352458517699289. Epub 2017 Mar 1. PMID: 28287051

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS Med. 2015 Aug ;12(8):e1001866. Epub 2015 Aug 25. PMID: 26305103

Pubmed Data : Mult Scler. 2009 Jan;15(1):116-9. Epub 2008 Sep 19. PMID: 18805844

[+]

Mat Pilates and reformer Pilates had beneficial effects in patients with Multiple sclerosis.Dec 31, 2016

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Pubmed Data : NeuroRehabilitation. 2017 ;41(2):413-422. PMID: 28946576

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Multiple Sclerosis

Therapeutic Actions : Pilates

Additional Keywords : Multiple Sclerosis, Pilates

[+]

Melatonin exerts beneficial effects in MS patients based on its' proved antioxidative properties.Mar 31, 2016

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Pubmed Data : J Physiol Pharmacol. 2016 Apr ;67(2):235-42. PMID: 27226183

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Pubmed Data : Am J Epidemiol. 1997 Jun 15;145(12):1076-88. PMID: 9199537

Article Published Date : Jun 15, 1997

Study Type : Human Study

Additional Links

Diseases : Amyotrophic Lateral Sclerosis

Problem Substances : Agricultural Chemicals, Pesticides

Adverse Pharmacological Actions : Neurotoxic

[+]

Omega 3 fatty acids have therapeutic value in the treatment of Mulitple Sclerosis. Feb 01, 2009

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Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2009 Feb-Mar;80(2-3):131-6. Epub 2009 Jan 25. PMID: 19171471

Article Published Date : Feb 01, 2009

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids

Diseases : Multiple Sclerosis

[+]

Selenium, glutathione, copper/zinc and superoxide dismutase may have therapeutic value in ALS. Jan 01, 1995

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Pubmed Data : Scand J Rheumatol. 1995;24(2):85-93. PMID: 9726810

Article Published Date : Jan 01, 1995

Study Type : Human Study

Additional Links

Substances : Antioxidant formulas, Copper, Glutathione, Selenium, Superoxide dismutase, Zinc

Diseases : Amyotrophic Lateral Sclerosis

Pharmacological Actions : Calcium Channel Blockers

[+]

Serum homocysteine may play a role in cognitive dysfunction in MS patients.Feb 20, 2018

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Pubmed Data : Int J Neurosci. 2018 Feb 21:1-7. Epub 2018 Feb 21. PMID: 29384421

Article Published Date : Feb 20, 2018

Study Type : Human Study

Additional Links

Diseases : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Multiple Sclerosis

Additional Keywords : Cognitive Decline/Dysfunction, Homocysteine: Elevated, Multiple Sclerosis, Risk Factors

[+]

Click here to read the entire abstract

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Pubmed Data : Front Microbiol. 2019 ;10:2410. Epub 2019 Oct 24. PMID: 31708890

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Inflammatory Bowel Diseases, Multiple Sclerosis

Therapeutic Actions : Sunlight exposure

Pharmacological Actions : Gastrointestinal Agents

[+]

Some behavioural and/or psychological features associated with falling in love could be related to raised neural growth factor (NGF) levels in the bloodstream.Apr 01, 2006

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Pubmed Data : Psychoneuroendocrinology. 2006 Apr;31(3):288-94. Epub 2005 Nov 10. PMID: 16289361

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Immunobiology. 2016 Apr ;221(4):512-5. Epub 2015 Dec 18. PMID: 26724970

Article Published Date : Apr 01, 2016

Study Type : Human Study

Additional Links

Diseases : Multiple Sclerosis

Additional Keywords : Vaccine Research

Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus

Adverse Pharmacological Actions : Immunotoxic, Neurotoxic

[+]

Suboptimal vitamin D levels are frequently found in ALS patients (81%). Oct 31, 2013

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Pubmed Data : J Clin Neurosci. 2013 Nov ;20(11):1550-3. Epub 2013 Jun 29. PMID: 23815870

Article Published Date : Oct 31, 2013

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Amyotrophic Lateral Sclerosis, Vitamin D Deficiency

[+]

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.Jan 04, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Proc Natl Acad Sci U S A. 2021 Jan 5 ;118(1). PMID: 33376202

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THC/CBD oromucosal spray has shown to be effective in improving overactive bladder symptoms in multiple sclerosis patients.Oct 18, 2017

Click here to read the entire abstract

Pubmed Data : Neurol Sci. 2017 Oct 19. Epub 2017 Oct 19. PMID: 29052091

Article Published Date : Oct 18, 2017

Study Type : Human Study

Additional Links

Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Multiple Sclerosis, Overactive Bladder

[+]

THC:CBD oromucosal spray provided symptomatic relief of MS spasticity with good tolerability in a relevant number of previously resistant patients.Dec 31, 2014

Click here to read the entire abstract

Pubmed Data : Eur Neurol. 2015 ;74(3-4):178-85. Epub 2015 Nov 17. PMID: 26571097

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Pubmed Data : NeuroRehabilitation. 2019 Aug 19. Epub 2019 Aug 19. PMID: 31450521

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Microbiol. 2017 ;8:1141. Epub 2017 Jun 28. PMID: 28702003

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Multiple Sclerosis

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Microbiome

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The Mindfulness-integrated cognitive behaviour therapy affects depression, anxiety and hope of multiple sclerosis patients.Dec 31, 2019

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Pubmed Data : Trends Psychiatry Psychother. 2020 Jan-Mar;42(1):55-63. PMID: 32321085

Pubmed Data : J Immunol. 2004 Jan 1;172(1):661-8. PMID: 14688379

Article Published Date : Jan 01, 2004

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These results found that preonset sun exposure was protective against subsequent conversion to MS and relapses.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Neurol. 2018 ;9:16. Epub 2018 Feb 1. PMID: 29449827

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Pubmed Data : J Neuroimmune Pharmacol. 2014 Dec 24. Epub 2014 Dec 24. PMID: 25537576

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Pubmed Data : Neurobiol Dis. 2017 Dec ;108:249-260. Epub 2017 Sep 6. PMID: 28888971

Article Published Date : Nov 30, 2017

Study Type : Human In Vitro

Additional Links

Diseases : Amyotrophic Lateral Sclerosis, Fungus Diseases

[+]

Modulation of Th17 proliferation and IL-17A gene expression by acetylated form of apigenin in patients with multiple sclerosis.Feb 25, 2020

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Pubmed Data : Immunol Invest. 2020 Feb 26:1-14. Epub 2020 Feb 26. PMID: 32100582

Article Published Date : Feb 25, 2020

Study Type : Human In Vitro

Additional Links

Substances : Apigenin

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation

[+]

Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG.Sep 01, 2007

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Pubmed Data : Curr Alzheimer Res. 2007 Sep ;4(4):403-11. PMID: 17908043

Article Published Date : Sep 01, 2007

Study Type : Human In Vitro

Additional Links

Substances : Catechin

Diseases : Amyotrophic Lateral Sclerosis, Huntington Disease, Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents, Regenerative

Additional Keywords : Nerve Regeneration

[+]

A case of a group of Japanese patients who died after rabies vaccination, exhibiting lesions similar to that of multiple sclerosis.Dec 13, 1901

Click here to read the entire abstract

Pubmed Data : . PMID: The nature of multiple sclerosis.

Study Type : Human: Case Report

Additional Links

Diseases : Multiple Sclerosis

Anti Therapeutic Actions : Vaccination: All, Vaccination: Rabies

[+]

A case of multiple sclerosis improvement following removal of heavy metal intoxication has been reported.Mar 22, 2012

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Pubmed Data : Biometals. 2012 Mar 22. Epub 2012 Mar 22. PMID: 22438029

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Eur J Clin Microbiol Infect Dis. 2011 May 1. Epub 2011 May 1. PMID: 21533622

Article Published Date : May 01, 2011

Study Type : Human: Case Report

Additional Links

Diseases : Candidiasis, Fungal Infection, Multiple Sclerosis

Additional Keywords : Diseases that are Linked

[+]

GcMAF shows therapeutic potency in the treatment of Multiple sclerosis.Jun 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Anticancer Res. 2016 Jul ;36(7):3771-4. PMID: 27354653

Article Published Date : Jun 30, 2016

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Pubmed Data : Curr Aging Sci. 2011 Aug 12. Epub 2011 Aug 12. PMID: 21834785

Article Published Date : Aug 12, 2011

Study Type : Human: Case Report

Additional Links

Diseases : Multiple Sclerosis

Problem Substances : Cadmium, Industrial Copper (inorganic), Lead

[+]

Lead toxicitity may be associated with ALS. May 01, 1998

Click here to read the entire abstract

Pubmed Data : Rev Neurol (Paris). 1998 May;154(4):345-7. PMID: 9773065

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Pubmed Data : J Biochem Mol Toxicol. 2020 Jul 8:e22564. Epub 2020 Jul 8. PMID: 32640490

Article Published Date : Jul 07, 2020

Study Type : Animal Study

Additional Links

Substances : Ellagic Acid

Diseases : Multiple Sclerosis

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

"Amniotic epithelial cells from the human placenta potently suppress a mouse model of multiple sclerosis."Jan 01, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2012 ;7(4):e35758. Epub 2012 Apr 26. PMID: 22563398

Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cell Neurosci. 2020 ;14:116. Epub 2020 May 12. PMID: 32477069

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Neem

Diseases : Brain Inflammation , Hepatitis, Multiple Sclerosis

Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents

[+]

Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models.Dec 31, 2009

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Pubmed Data : J Neuroinflammation. 2010 ;7:69. Epub 2010 Oct 15. PMID: 20950451

Article Published Date : Dec 31, 2009

Study Type : Animal Study

Additional Links

Substances : Bee Venom

Diseases : Amyotrophic Lateral Sclerosis

[+]

Beneficial effects of Thymus vulgaris extract in experimental autoimmune encephalomyelitis.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Mol Sci. 2017 Apr 1 ;18(4). Epub 2017 Apr 1. PMID: 28368293

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Pubmed Data : Amyotroph Lateral Scler Other Motor Neuron Disord. 2005 Sep;6(3):182-4. PMID: 16183560

Article Published Date : Sep 01, 2005

Study Type : Animal Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Amyotrophic Lateral Sclerosis

[+]

Cannabis contains a number of compounds which may have therapeutic value in delaying the progression of ALS. Mar 01, 2004

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Pubmed Data : Amyotroph Lateral Scler Other Motor Neuron Disord. 2004 Mar;5(1):33-9. PMID: 15204022

Article Published Date : Mar 01, 2004

Study Type : Animal Study

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Substances : Cannabinoids , Cannabis

Diseases : Amyotrophic Lateral Sclerosis

Pharmacological Actions : Neuroprotective Agents

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Cannabis extracts have therapeutic potential to slow multiple sclerosis progression and repair the central nervous system.Jun 30, 2015

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Pubmed Data : Br J Pharmacol. 2015 Jul ;172(14):3579-95. Epub 2015 May 20. PMID: 25857324

Article Published Date : Jun 30, 2015

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunomodulatory

Additional Keywords : Plant Extracts

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[+]

Chrysin suppress immune responses and protects from experimental autoimmune encephalomyelitis in mice.Oct 14, 2019

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Pubmed Data : J Neuroimmunol. 2019 Oct 15 ;335:577007. Epub 2019 Jul 16. PMID: 31376787

Article Published Date : Oct 14, 2019

Study Type : Animal Study

Additional Links

Substances : Chrysin

Diseases : Multiple Sclerosis

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Co-administration of IGF-I and glycosaminoglycans greatly delays motor neuron disease in the mouse model.Apr 01, 2002

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Pubmed Data : J Neurochem. 2002 Apr;81(1):194-202. PMID: 12067233

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Pubmed Data : J Neurol Sci. 2008 May 15;268(1-2):40-7. Epub 2007 Dec 4. PMID: 18054961

Article Published Date : May 15, 2008

Study Type : Animal Study

Additional Links

Substances : Estradiol (E(2))

Diseases : Amyotrophic Lateral Sclerosis

Pharmacological Actions : Neuroprotective Agents

[+]

Evening primrose/hemp seed oil was able to reduce the severity of autoimmune encephalomyelitis and inhibited the development of the disease.Apr 15, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Allergy Asthma Immunol. 2020 Apr 16 ;19(2):183-192. Epub 2020 Apr 16. PMID: 32372631

Article Published Date : Apr 15, 2020

Study Type : Animal Study

Additional Links

Substances : Evening Primrose Oil, Hemp Seed

Diseases : Multiple Sclerosis

Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer, Interleukin-10 upregulation

[+]

Exercise modulates the levels of growth inhibitor genes before and after multiple sclerosis.Jan 29, 2020

Click here to read the entire abstract

Pubmed Data : J Neuroimmunol. 2020 Jan 30 ;341:577172. Epub 2020 Jan 30. PMID: 32028123

Article Published Date : Jan 29, 2020

Study Type : Animal Study

Additional Links

Diseases : Multiple Sclerosis

Therapeutic Actions : Exercise

Additional Keywords : Gene Expression Regulation

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View the Evidence: 592 Abstracts with Demyelinating Diseases Research

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Association of exposure to particulate matters and multiple sclerosis.Jun 15, 2021

Cannabinoids may have possible therapeutic properties for the management of the multiple sclerosis.Nov 19, 2010

Dental amalgams (mercury exposure) increase the risk of multiple sclerosis. Jan 01, 2007

In this meta-analysis, there was an observed increased risk of amytrophic lateral sclerosis in workers occupationally exposed to extremely low frequency electromagnetic fields. Feb 01, 2018

Low maternal exposure to ultraviolet radiation in pregnancy is associated with increased risk of multiple sclerosis in offspring. Jan 01, 2010

Mind-body medicine for multiple sclerosis: a systematic review.Dec 31, 2011

Pilates is a feasible therapy for people with multiple sclerosis that can lead to improvements on their physical function.Jan 31, 2019

There is a relation between Epstein-Barr virus and multiple sclerosis.Jul 01, 2010

There is a strong association between UV radiation (sunlight exposure) and multiple sclerosis.Aug 01, 2009

There is an association between occupational exposure to power frequency electromagnetic fields and amyotrophic lateral sclerosis.Feb 01, 2003

These findings suggest that vitamin D supplementation may have a therapeutic role in the treatment of multiple sclerosis.Oct 02, 2018

Whole plant cannabis provides subjective symptom relief in multiple sclerosis. Jan 01, 2009

High-dose vitamin B supplementation for persistent visual deficit in multiple sclerosis.Dec 31, 2019

"Chart-confirmed guillain-barre syndrome after 2009 H1N1 influenza vaccination among the Medicare population, 2009-2010."Sep 14, 2013

"Risk of Guillain-Barré syndrome after 2010-2011 influenza vaccination."Apr 30, 2013

"Risk of Guillain-Barré syndrome after 2010-2011 influenza vaccination."Apr 30, 2013

"Yellow fever vaccination and increased relapse rate in travelers with multiple sclerosis."Oct 01, 2011

A high intake of poluunsaturated fatty acids and vitamin E is associated with a 50-60% decreased risk of developing ALS. Apr 01, 2007

A higher intake of food rich in antioxidants such as fruit and vegetables confer protection against the development of ALS.Dec 19, 2003

A majority of patients with amyotrophic lateral sclerosis had signs of intestinal inflammation.Aug 31, 2017

A Mediterranean diet rich in olive oil may have a protective role in multiple sclerosis. Jun 01, 2009

A modified Mediterranean dietary intervention reduced fatigue in multiple sclerosis patients. Sep 23, 2019

Ai-Chi aquatic exercise improves the condition of patients with multiple sclerosis. Jan 01, 2012

Ai-Chi may improve balance, functional mobility, upper and lower extremity muscle strength and fatigue in patients with Multiple sclerosis.Dec 31, 2012

Air pollution by particulate matter PM10 may trigger multiple sclerosis relapses.Jun 30, 2017

An ALS-specific meditation programme is beneficial for the quality of life and psychological well-being of people with ALS.Mar 31, 2017

Antibodies to gliadin are more common in demyelinating diseases of the nervous sytem. Jan 06, 2013

Antibody titers against EBV in MS patients rise after the onset of the disease and indicate that vitamin D3 supplementation could limit augmentation of these titers in MS patients.Feb 28, 2015

Antioxidative effects of silymarin on the reduction of liver complications of fingolimod in patients with relapsing-remitting multiple sclerosis.May 01, 2021

Autologous bone marrow-derived stem cell therapy is safe and feasible in patients of ALS.Aug 31, 2012

Bifidobacterium alleviated Guillain-Barré syndrome by regulating Th cells.Jul 31, 2018

Biofeedback improves bowel symptoms in patients with multiple sclerosis. Sep 01, 2011

Breathing exercises may be beneficial in patients with mild to moderate stages of multiple sclerosis.Oct 31, 2016

Candida infection is more common in multiple sclerosis patients.Sep 01, 2010

Cannabis extracts can be a useful and safe option for patients with MS with moderate to severe spasticity resistant to common antispastic drugs.May 08, 2016

Cannabis-based extracts have therapeutic value for bladder dysfunction in advanced mutiple sclerosis. Aug 01, 2004

Cannabis-based medicine is effective in reducing pain and sleep disturbance in patients with multiple sclerosis related central neuropathic pain and is mostly well tolerated.Sep 27, 2005

Cannabis-based medicine may represent a useful new agent for treatment of the symptomatic relief of spasticity in MS.Feb 28, 2007

Celiac disease has been associated with recurrent guillain barre syndrome.Sep 07, 2010

Cesarean delivery appears to increase the risk of multiple sclerosis.Oct 07, 2011

Cigarette smoking is associated with increased risk for ALS. Jan 01, 1999

Clinically apparent chickenpox is associated with a lower risk of childhood-onset multiple sclerosis.May 15, 2009

Coenzyme Q10 levels as high as 3,000 mg a day are safe and well-tolerated in ALS patients. Dec 13, 2005

Coenzyme Q10 supplementation reduces peripheral oxidative stress and inflammation in interferon-β1a-treated multiple sclerosis.Dec 31, 2018

Continuous fingolimod treatment has been linked to nasopharyngitis (34%), headache (30%), fatigue (19%) and influenza (18%). Feb 01, 2010

CoQ10 supplementation at a dosage of 500 mg appears to decrease inflammatory markers in patients with MS.Apr 30, 2015

Craniosacral therapy is effective for treating lower urinary tract symptoms and improving quality of life in multiple sclerosis patients. May 01, 2009

Creatine may have therapeutic activity in patients with Charcot-Marie-Tooth disease.Nov 01, 2006

Cumulative gadodiamide administration leads to brain gadolinium deposition in early multiple sclerosis.Aug 05, 2019

Delta-tetrahydrocannabinol (THC) and cannabidiol have therapeutic value in the management of spasticity associated wtih multiple sclerosis. Aug 01, 1996

Diaphragm training has value in amyotrophic lateral sclerosis.Nov 30, 2008

Dronabinol is a safe long-term treatment option for neuropathic pain patients.Oct 25, 2017

Effect of ultraviolet irradiation of autologous blood on cell volumes, cell adhesion and phagocytosis in normal probands and patients with multiple sclerosis.Dec 31, 1987

Effects of aquatic exercises on postural control and hand function in multiple sclerosis.May 31, 2020

EGCG and coconut oil improve state anxiety and functional capacity in patients with multiple sclerosis.Jan 22, 2020

EGCG given to patients with multiple sclerosis over 12 weeks improved muscle metabolism during moderate exercise to a greater extent in men than in women.Feb 28, 2015

Epstein-Barr virus infection may be associated with increased risk of multiple sclerosisDec 26, 2001

Evening primrose oil has beneficial effects on fatigue and quality of life in patients with multiple sclerosis.Dec 31, 2017

Evidence of Clostridium perfringens epsilon toxin associated with multiple sclerosis.Mar 31, 2018

Exercise effects on multiple sclerosis quality of life and clinical-motor symptoms.Dec 22, 2019

Exercise may be an additional modifiable protective factor for multiple sclerosis.Feb 28, 2017

Existential well-being, as well as spirituality issues, perceived by SALS patients seems to be directly related with quality of life, severity of mood disturbance and burden experienced by their caregivers.Feb 28, 2011

Exposure to pesticides like chlorpyrifos may contribute to the pathogenesis of multiple sclerosis. May 01, 2002

Fingolimod has been linked to a wide variety of side effects, including fatal viral infection.Feb 04, 2010

Fingolimod treatment is associated with a number of adverse side effects.Feb 04, 2010

Flavonoid rich dark cocoa may improve fatigue in people with multiple sclerosis.Sep 30, 2017

Free testosterone is significantly decreased in ALS, indicating that supplementation with testosterone may have a therapeutic role in ALS treatment. Mar 15, 2002

Genetically lowered 25OHD level is associated with an increase in the risk of MS in people of European descent.Jul 31, 2015

Geomagnetic and solar activity may represent an environmental health risk factor for multiple sclerosis.Jun 30, 2016

Glutamate levels may contribute to the pathogenesis of ALS.Feb 01, 2010

Gluten sensitivity is a clinically confirmed problem in multiple sclerosis.Sep 01, 2009

Guided imagery improves mood, fatigue, and quality of life in individuals with multiple sclerosis.Dec 31, 2017

Demyelinating Diseases

View the Evidence:
592 Abstracts with Demyelinating Diseases Research