Drug-Induced Nutrient Depletion: Vitamin B-12

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1 Substances Researched for Drug-Induced Nutrient Depletion: Vitamin B-12
NameACCKFocus
Vitamin B-12330Locked
4 Problem Substances Researched for Drug-Induced Nutrient Depletion: Vitamin B-12
NameACCKFocus
Metformin 330Locked
Proton-Pump Inhibitors314Locked
Histamine Receptor Antagonists110Locked
Ranitidine110Locked

View the Evidence:
9 Abstracts with Drug-Induced Nutrient Depletion: Vitamin B-12 Research

[+]

Aspirin use is associated with a higher rate of vitamin B12 deficiency in patients hospitalized with cardiovascular disease.Oct 01, 2004

Pubmed Data : Am J Cardiol. 2004 Oct 1;94(7):975-7. PMID: 15464695
Article Published Date : Oct 01, 2004
Study Type : Human Study
Additional Links
Diseases : Aspirin-Induced Toxicity , Drug-Induced Nutrient Depletion: Aspirin, Drug-Induced Nutrient Depletion: Vitamin B-12, Vitamin B 12 Deficiency
Pharmacological Actions : Platelet Aggregation Inhibitors
Additional Keywords : Aspirin-Vitamin b12 Deficiency, Drug-Nutrient Depletion
[+]

Hyperglycemia and metformin use are associated With B vitamin deficiency and cognitive dysfunction in older adults.Sep 30, 2019

Pubmed Data : J Clin Endocrinol Metab. 2019 Oct 1 ;104(10):4837-4847. PMID: 30920623
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Cognitive Decline/Dysfunction, Drug-Induced Nutrient Depletion: Vitamin B-12, Vitamin B 12 Deficiency
Additional Keywords : Risk Factors
Problem Substances : Metformin
[+]

Prolonged acid suppression therapy with PPIs or H2 blockers may result in serum vitamin B12 deficiency.Oct 20, 2020

Pubmed Data : Ir J Med Sci. 2020 Oct 21. Epub 2020 Oct 21. PMID: 33085017
Article Published Date : Oct 20, 2020
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Nutrient Depletion: Vitamin B-12
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Ranitidine inhibits the secretion of gastric intrinsic factor and absorption of vitamin B 12Apr 01, 1983

Pubmed Data : Gastroenterol Clin Biol. 1983 Apr ;7(4):381-4. PMID: 6135642
Article Published Date : Apr 01, 1983
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Acid Reflux, Drug-Induced Nutrient Depletion: Vitamin B-12, Vitamin B 12 Deficiency
Pharmacological Actions : Anti-Ulcer Agents
Problem Substances : Histamine Receptor Antagonists, Ranitidine
[+]

The prevalence of vitamin B12 deficiency is considerable among diabetic patients on metformin therapy.Jan 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sultan Qaboos Univ Med J. 2020 Feb ;20(1):e90-e94. Epub 2020 Mar 9. PMID: 32190375
Article Published Date : Jan 31, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Drug-Induced Nutrient Depletion: Vitamin B-12, Vitamin B 12 Deficiency
Additional Keywords : Risk Factors
Problem Substances : Metformin
[+]

The prevalence of vitamin B12 deficiency was significantly high in diabetics, especially the metformin-treated patients.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : SAGE Open Med. 2019 ;7:2050312119853433. Epub 2019 May 23. PMID: 31205703
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Drug-Induced Nutrient Depletion: Vitamin B-12, Vitamin B 12 Deficiency
Additional Keywords : Risk Factors
Problem Substances : Metformin
[+]

Vitamin B12 deficiency and diabetic neuropathy are very high among metformin-treated T2DM patients.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2021 ;16(3):e0249325. Epub 2021 Mar 30. PMID: 33784336
Article Published Date : Dec 31, 2020
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Drug-Induced Nutrient Depletion: Vitamin B-12
Additional Keywords : Risk Factors
[+]

This case report describes a case of PPI-induced thrombocytopenia.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Case Rep Gastrointest Med. 2018 ;2018:4294805. Epub 2018 Apr 30. PMID: 29854491
Article Published Date : Dec 31, 2017
Study Type : Human: Case Report, Review
Additional Links
Diseases : Drug-Induced Nutrient Depletion: Vitamin B-12, Osteoporosis, Thrombocytopenia
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term use of proton pump inhibitors as a risk factor for various adverse manifestations.Jul 08, 2020

Pubmed Data : Therapie. 2020 Jul 9. Epub 2020 Jul 9. PMID: 32718584
Article Published Date : Jul 08, 2020
Study Type : Review
Additional Links
Diseases : Drug-Induced Nutrient Depletion: Vitamin B-12, Mineral Deficiencies, Vitamin C Deficiency
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors

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Drug-Induced Nutrient Depletion: Vitamin B-12 Related Articles

Vitamin B12 Deficiency and Brain Health
Written by Kelly Brogan, M.D.
One of the most remarkable papers I have read in the psychiatric literature was about a 57 year old woman who was treated with months of both antipsychotic and antidepressant medications and given two rounds of electroconvulsive treatment before anyone bothered to check her vitamin B12 level.
Vitamin B Deficiency: Why Vitamin Pills Are Not Enough
Written by Vic Shayne, Ph.D.
Real foods contain a host of nutrients that vitamin pills do not. And we need these other nutrients — often more than the vitamin itself — for healing, prevention and cellular function.
Vitamin B12 Deficiency and Brain Health
Written by Kelly Brogan, M.D.
One of the most remarkable papers I have read in the psychiatric literature was about a 57 year old woman who was treated with months of both antipsychotic and antidepressant medications and given two rounds of electroconvulsive treatment before anyone bothered to check her vitamin B12 level.
Vitamin B Deficiency: Why Vitamin Pills Are Not Enough
Written by Vic Shayne, Ph.D.
Real foods contain a host of nutrients that vitamin pills do not. And we need these other nutrients — often more than the vitamin itself — for healing, prevention and cellular function.

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