Dysbiosis

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65 Substances Researched for Dysbiosis
38 Problem Substances Researched for Dysbiosis
2 Therapeutic Actions Researched for Dysbiosis
6 Problematic Actions Researched for Dysbiosis
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View the Evidence:
404 Abstracts with Dysbiosis Research

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Pubmed Data : Food Funct. 2016 Jul 13 ;7(7):3224-32. PMID: 27334000
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Dysbiosis
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Microbiota
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Pubmed Data : Curr Microbiol. 2012 Dec 9. Epub 2012 Dec 9. PMID: 23224412
Study Type : Bacterial
Additional Links
Diseases : Dysbiosis
Problem Substances : Glyphosate
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Infect Microbiol. 2017 ;7:396. Epub 2017 Sep 8. PMID: 28936425
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : Lancet Oncol. 2018 Jun ;19(6):e295-e304. Epub 2018 Jun 1. PMID: 29893261
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : Hepatobiliary Pancreat Dis Int. 2018 Nov 22. Epub 2018 Nov 22. PMID: 30527903
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : J Invest Dermatol. 2017 Nov ;137(11):2253-2255. PMID: 29055411
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
Problem Substances : Antibiotics
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Pubmed Data : Curr Pain Headache Rep. 2020 Jun 6 ;24(7):36. Epub 2020 Jun 6. PMID: 32506238
Study Type : Review
Additional Links
Diseases : Depression, Dysbiosis
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Metab Dispos. 2015 Oct ;43(10):1557-71. Epub 2015 Apr 7. PMID: 25852213
Study Type : Review
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Pubmed Data : J Autism Dev Disord. 2017 Feb ;47(2):480-489. PMID: 27882443
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Virus Res. 2020 May 13 ;285:198018. Epub 2020 May 13. PMID: 32430279
Study Type : Review
Additional Links
Substances : Probiotics
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Risk Factors
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Pubmed Data : Rev Endocr Metab Disord. 2018 Oct 8. Epub 2018 Oct 8. PMID: 30294759
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Pubmed Data : Am J Hypertens. 2020 Jul 2. Epub 2020 Jul 2. PMID: 32614942
Study Type : Review
Additional Links
Substances : Probiotics
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Pubmed Data : Chemosphere. 2019 Jul ;227:425-434. Epub 2019 Apr 13. PMID: 31003127
Study Type : Review
Additional Links
Problem Substances : Pesticides
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Pubmed Data : Curr Opin Neurobiol. 2020 Feb 14 ;62:92-101. Epub 2020 Feb 14. PMID: 32066076
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Pubmed Data : Lett Appl Microbiol. 2000 Jun ;30(6):453-5. PMID: 10849275
Study Type : Bacterial
Additional Links
Substances : Honey, Prebiotics
Diseases : Dysbiosis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Wiley Interdiscip Rev Syst Biol Med. 2018 05 ;10(3):e1413. Epub 2018 Jan 9. PMID: 29316320
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiota
Anti Therapeutic Actions : Vaccination: All
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Pubmed Data : Immunology. 2018 Dec 17. Epub 2018 Dec 17. PMID: 30560993
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Sci (Lond). 2018 Nov 30 ;132(22):2387-2389. Epub 2018 Nov 19. PMID: 30455339
Study Type : Review
Additional Links
Therapeutic Actions : Microbiota Transfer Therapy
Additional Keywords : Microbiota
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Pubmed Data : Neurobiol Dis. 2019 Dec 11:104704. Epub 2019 Dec 11. PMID: 31837420
Study Type : In Vitro Study
Additional Links
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2017 Aug 14 ;23(30):5486-5498. PMID: 28852308
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Pubmed Data : Psychother Psychosom. 2017 ;86(1):31-46. Epub 2016 Nov 25. PMID: 27884012
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2018 ;9:432. Epub 2018 Mar 12. PMID: 29593681
Study Type : Review
Additional Links
Additional Keywords : Microbiome, Risk Factors
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Pubmed Data : Ann Nutr Metab. 2020 Jan 24:1-14. Epub 2020 Jan 24. PMID: 31982866
Study Type : Review
Additional Links
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut Microbes. 2015 ;6(3):207-13. PMID: 25835343
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Nutr. 2020 Feb 3:1-23. Epub 2020 Feb 3. PMID: 32008579
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : Expert Rev Gastroenterol Hepatol. 2018 Oct ;12(10):985-996. Epub 2018 Sep 3. PMID: 30146910
Study Type : Review
Additional Links
Therapeutic Actions : Microbiota Transfer Therapy
Pharmacological Actions : Gastrointestinal Agents
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Transl Immunology. 2016 Jul ;5(7):e90. Epub 2016 Jul 15. PMID: 27525063
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Dysbiosis, Sepsis
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Microbiota
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Pubmed Data : Genes Nutr. 2011 Aug ;6(3):241-60. Epub 2011 May 11. PMID: 21559992
Study Type : Review
Additional Links
Diseases : Dysbiosis, Obesity
Additional Keywords : Diseases that are Linked
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Pubmed Data : Z Rheumatol. 2016 Dec 1. Epub 2016 Dec 1. PMID: 27909795
Study Type : Review
Additional Links
Substances : Prebiotics, Probiotics
Pharmacological Actions : Anti-Inflammatory Agents
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Pubmed Data : J Agric Food Chem. 2009 Sep 23;57(18):8344-9. PMID: 19705832
Study Type : In Vitro Study
Additional Links
Diseases : Dysbiosis
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Pubmed Data : Anaerobe. 2015 Aug ;34:164-8. Epub 2015 Jun 4. PMID: 26051169
Study Type : In Vitro Study
Additional Links
Diseases : Dysbiosis
Additional Keywords : Microbiota, Plant Extracts
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Pubmed Data : Med Hypotheses. 2019 Sep 26 ;134:109410. Epub 2019 Sep 26. PMID: 31627123
Study Type : Review
Additional Links
Substances : Prebiotics, Probiotics
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Pubmed Data : Gastroenterol Clin North Am. 2019 09 ;48(3):389-405. Epub 2019 Jun 12. PMID: 31383278
Study Type : Review
Additional Links
Diseases : Depression, Dysbiosis
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2017 Jun 9 ;6(6). Epub 2017 Jun 9. PMID: 28598360
Study Type : Review
Additional Links
Additional Keywords : Microbiota, Risk Reduction
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Pubmed Data : J Int Acad Periodontol. 2020 Apr 1 ;22(2):18-27. Epub 2020 Apr 1. PMID: 32224547
Study Type : In Vitro Study
Additional Links
Diseases : Dysbiosis, Gingivitis
Pharmacological Actions : Antimicrobial, Gastrointestinal Agents
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Pubmed Data : Eur J Pediatr. 2016 Aug 30. Epub 2016 Aug 30. PMID: 27576473
Study Type : Review
Additional Links
Substances : Probiotics
Pharmacological Actions : Gastrointestinal Agents
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Pubmed Data : Psychosom Med. 2017 Aug 11. Epub 2017 Aug 11. PMID: 28806201
Study Type : Review
Additional Links
Diseases : Dysbiosis
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2019 Jun 14 ;25(22):2706-2719. PMID: 31235994
Study Type : Review
Additional Links
Diseases : Dysbiosis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
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Pubmed Data : Biosci Biotechnol Biochem. 2008 Mar;72(3):773-7. Epub 2008 Mar 7. PMID: 18323655
Study Type : In Vitro Study
Additional Links
Substances : Rose , Tannic Acid
Additional Keywords : Plant Extracts, Prebiotic
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Pubmed Data : Nutr Clin Pract. 2012 Feb 29. Epub 2012 Feb 29. PMID: 22378800
Study Type : Review
Additional Links
Substances : Probiotics
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Pubmed Data : Adv Exp Med Biol. 2019 ;1118:253-269. PMID: 30747427
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Pubmed Data : Neurologia. 2019 Jul 21. Epub 2019 Jul 21. PMID: 31340904
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Transl Immunology. 2016 Apr ;5(4):e72. Epub 2016 Apr 15. PMID: 27195115
Study Type : Review
Additional Links
Additional Keywords : Microbiota, Risk Factors
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Dev Disord Rep. 2016 Mar ;3(1):75-81. Epub 2016 Feb 26. PMID: 27398286
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiota
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Pubmed Data : Physiol Behav. 2016 Apr 14. Epub 2016 Apr 14. PMID: 27090230
Study Type : Bacterial
Additional Links
Additional Keywords : Microbiota, Risk Factors
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Pubmed Data : J Agric Food Chem. 2005 Feb 23;53(4):1152-7. PMID: 15713033
Study Type : In Vitro Study
Additional Links
Substances : Pau D'Arco
Diseases : Dysbiosis
Pharmacological Actions : Anti-Bacterial Agents
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Mol Gastroenterol Hepatol. 2018 ;6(2):133-148. Epub 2018 Apr 12. PMID: 30023410
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Pubmed Data : Anaerobe. 2008 Feb;14(1):29-34. Epub 2007 Nov 26. PMID: 18042411
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Inulin
Diseases : Dysbiosis
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Pubmed Data : Nephrol Dial Transplant. 2020 May 21. Epub 2020 May 21. PMID: 32437554
Study Type : Review
Additional Links
Substances : Probiotics
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory
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Pubmed Data : Pediatr Res. 2019 Jan ;85(2):216-224. Epub 2018 Sep 25. PMID: 30283047
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dev Neurobiol. 2018 05 ;78(5):474-499. Epub 2018 Feb 20. PMID: 29411548
Study Type : Review
Additional Links
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Pubmed Data : Microb Pathog. 2019 Jul ;132:188-192. Epub 2019 Apr 27. PMID: 31039390
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : FEMS Microbiol Rev. 2015 Jul ;39(4):567-91. Epub 2015 May 3. PMID: 25940667
Study Type : Review
Additional Links
Additional Keywords : Microbiome
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Pubmed Data : Am J Respir Crit Care Med. 2017 Oct 19. Epub 2017 Oct 19. PMID: 29048927
Study Type : Review
Additional Links
Diseases : Asthma, Dysbiosis
Additional Keywords : Risk Factors
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Pubmed Data : Altern Med Rev. 2009 Dec;14(4):380-4. PMID: 20030464
Study Type : In Vitro Study
Additional Links
Substances : Ajwain, Caraway , Lavender, Orange
Diseases : Dysbiosis
Pharmacological Actions : Anti-Bacterial Agents
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2019 ;10:574. Epub 2019 Jun 4. PMID: 31214110
Study Type : Review
Additional Links
Substances : Probiotics
Additional Keywords : Gut-brain Axis
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Pubmed Data : Curr Neurol Neurosci Rep. 2018 Sep 24 ;18(11):81. Epub 2018 Sep 24. PMID: 30251184
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Pubmed Data : Biochem Biophys Res Commun. 2019 Apr 30 ;512(2):373-380. Epub 2019 Mar 18. PMID: 30898321
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Microbiol. 2018 ;9:1835. Epub 2018 Aug 14. PMID: 30154767
Study Type : Review
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Pubmed Data : Clin Lab Med. 2014 Dec ;34(4):771-785. Epub 2014 Sep 24. PMID: 25439276
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol Res. 2017 ;2017:7904821. Epub 2017 Feb 20. PMID: 28316999
Study Type : Review
Additional Links
Additional Keywords : Endocannabinoid System, Microbiota
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Pubmed Data : Autism. 2020 Apr 28:1362361320913364. Epub 2020 Apr 28. PMID: 32340474
Study Type : Review
Additional Links
Diseases : Autism, Dysbiosis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pediatr Rheumatol Online J. 2016 ;14(1):44. Epub 2016 Jul 22. PMID: 27448997
Study Type : Review
Additional Links
Additional Keywords : Microbiota, Risk Factors
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Aug 1 ;19(8). Epub 2018 Aug 1. PMID: 30071612
Study Type : Review
Additional Links
Diseases : Autism, Dysbiosis
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Apr 29 ;20(9). Epub 2019 Apr 29. PMID: 31035684
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Jun 10 ;21(11). Epub 2020 Jun 10. PMID: 32532137
Study Type : Review
Additional Links
Substances : Probiotics
Pharmacological Actions : Gastrointestinal Agents
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Psychiatry. 2018 ;9:205. Epub 2018 May 29. PMID: 29896124
Study Type : Review
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Pubmed Data : Cell Mol Life Sci. 2017 Oct 12. Epub 2017 Oct 12. PMID: 29026921
Study Type : Review
Additional Links
Diseases : Aging, Dysbiosis
Additional Keywords : Microbiota
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Pubmed Data : Med Hypotheses. 2017 Oct ;108:35-37. Epub 2017 Aug 1. PMID: 29055396
Study Type : Commentary
Additional Links
Additional Keywords : Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Appl Microbiol. 2019 Mar 28. Epub 2019 Mar 28. PMID: 30920075
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurosci Res. 2019 May 29. Epub 2019 May 29. PMID: 31144383
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Feb 22 ;12(2). Epub 2020 Feb 22. PMID: 32098380
Study Type : Review
Additional Links
Substances : Probiotics
Therapeutic Actions : Exercise
Pharmacological Actions : Gastrointestinal Agents
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Pubmed Data : Neurotoxicology. 2019 Aug 24 ;75:30-40. Epub 2019 Aug 24. PMID: 31454514
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : J Neuroendocrinol. 2019 May ;31(5):e12684. Epub 2019 Feb 1. PMID: 30614568
Study Type : Review
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Pubmed Data : Gastroenterol Clin North Am. 2019 09 ;48(3):407-431. Epub 2019 Jul 2. PMID: 31383279
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis
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Pubmed Data : Neurochem Int. 2018 Aug 13. Epub 2018 Aug 13. PMID: 30114473
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2012 ;7(12):e52132. Epub 2012 Dec 12. PMID: 23251695
Study Type : In Vitro Study
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Pubmed Data : Ann Neurol. 2011 Feb;69(2):240-7. PMID: 21387369
Study Type : Review
Additional Links
Substances : Probiotics
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Alzheimers Dis Parkinsonism. 2015 Mar ;5(1):177. PMID: 25977840
Study Type : Commentary
Additional Links
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Pubmed Data : Annu Rev Neurosci. 2017 Mar 8. Epub 2017 Mar 8. PMID: 28301775
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiome, Microbiota
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Pubmed Data : J Clin Endocrinol Metab. 2016 Mar 3:jc20154251. Epub 2016 Mar 3. PMID: 26938201
Study Type : Review
Additional Links
Substances : Prebiotics, Probiotics
Additional Keywords : Microbiome, Risk Factors
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Pubmed Data : Carcinogenesis. 2017 Aug 17. Epub 2017 Aug 17. PMID: 28968883
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Pubmed Data : Curr Opin Nephrol Hypertens. 2017 Jan ;26(1):1-8. PMID: 27798455
Study Type : Review
Additional Links
Additional Keywords : Microbiota, Risk Factors
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Jun 25 ;20(12). Epub 2019 Jun 25. PMID: 31242699
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2016 Jan 14 ;22(2):501-18. PMID: 26811603
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Pubmed Data : Expert Rev Gastroenterol Hepatol. 2016 Aug ;10(8):943-8. Epub 2016 Jun 22. PMID: 27291780
Study Type : Review
Additional Links
Substances : Bacillus Clausii
Pharmacological Actions : Antimicrobial, Immunomodulatory
Additional Keywords : Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut Microbes. 2014 May-Jun;5(3):369-80. Epub 2014 Mar 31. PMID: 24685620
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol Res. 2017 ;2017:4835189. Epub 2017 Aug 30. PMID: 28948174
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : Immunology. 2017 May 29. Epub 2017 May 29. PMID: 28556916
Study Type : Review
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Pubmed Data : J Alzheimers Dis. 2017 ;58(1):1-15. PMID: 28372330
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Neurosci. 2017 ;11:120. Epub 2017 Apr 28. PMID: 28503135
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiota
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Pubmed Data : Front Pharmacol. 2017 ;8:603. Epub 2017 Sep 1. PMID: 28919861
Study Type : Review
Additional Links
Pharmacological Actions : Chemopreventive, Chemotherapeutic
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Pubmed Data : Parkinsonism Relat Disord. 2017 Feb 7. Epub 2017 Feb 7. PMID: 28202372
Study Type : Review
Additional Links
Additional Keywords : Microbiota
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JCI Insight. 2017 Oct 5 ;2(19). Epub 2017 Oct 5. PMID: 28978799
Study Type : Review
Additional Links
Additional Keywords : Gut-liver axis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurogastroenterol Motil. 2016 Apr 30 ;22(2):201-12. PMID: 27032544
Study Type : Review
Additional Links
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Pubmed Data : Curr Obes Rep. 2016 Feb 11. Epub 2016 Feb 11. PMID: 26865085
Study Type : Review
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Pubmed Data : Eur Child Adolesc Psychiatry. 2017 Mar 13. Epub 2017 Mar 13. PMID: 28289903
Study Type : Review
[+]
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genes Environ. 2016 ;38:11. Epub 2016 Jun 1. PMID: 27350830
Study Type : Review
Additional Links
Substances : Probiotics
Additional Keywords : Microbiota, Risk Factors
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Med. 2019 Jul 7 ;8(7). Epub 2019 Jul 7. PMID: 31284694
Study Type : Review
Additional Links
Diseases : Acne, Dysbiosis
Additional Keywords : Microbiota
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Pubmed Data : Curr Pharm Des. 2016 Sep 6. Epub 2016 Sep 6. PMID: 27604604
Study Type : Review
Additional Links
Additional Keywords : Gut-brain Axis, Microbiota
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Pubmed Data : Int Immunopharmacol. 2019 Dec 23 ;79:106112. Epub 2019 Dec 23. PMID: 31877495
Study Type : Review
Additional Links
Substances : Vitamin D
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Res Med Sci. 2018 ;23:75. Epub 2018 Aug 23. PMID: 30181757
Study Type : Review
Additional Links
Additional Keywords : Risk Factors
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Pubmed Data : Fitoterapia. 2004 Dec;75(7-8):760-3. PMID: 15567259
Additional Links
Diseases : Dysbiosis
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Pubmed Data : J Am Coll Nutr. 2008 Feb;27(1):102-8. PMID: 18460488
Additional Links
Diseases : Dysbiosis

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