Fatty Liver

Name	AC	CK
Curcumin	21	77
Vitamin E	6	62
Silymarin	7	56
Coffee	5	53
Probiotics	11	50
Vitamin D	8	40
Omega-3 Fatty Acids	8	39
Genistein	5	36
Polyunsaturated Fatty Acids (PUFAs)	2	30
Taurine	3	28
Resveratrol	8	25
DHA (Docosahexaenoic Acid)	4	24
Polyphenols	8	22
Berberine	10	20
Gynostemma	1	20
Pantethine	1	20
Tea: Black	1	20
Tea: Green	1	20
Yoghurt	2	20
Black Currant	4	18
Anthocyanins	4	17
Green Tea	5	16
Spirulina	4	16
Astaxanthin	8	14
Bilberry	2	14
Blue Honeysuckle	6	14
EPA (Eicosapentaenoic Acid)	3	14
Flaxseed	3	14
Hydroxytyrosol	3	14
Licorice	3	14
Ginseng (Korean)	3	13
Pomegranate	3	13
Barberry	2	12
Broccoli	2	12
Cannabinoids	2	12
Carotenoids	2	12
Coenzyme Q10	2	12
Garlic	2	12
Olive Oil	3	12
Prebiotics	2	12
Sulforaphane	2	12
Vitamin C	2	12
Chocolate	2	11
Artichoke	1	10
Breast Milk	1	10
Calcium	1	10
Cannabis	1	10
Chlorella (Algae)	1	10
Cocoa	1	10
Fiber	1	10
Hibiscus sabdariffa	1	10
Krill	5	10
Lactobacilius bulgaricus	1	10
Magnesium	1	10
Nigella sativa (aka Black Seed)	1	10
Orange	1	10
Raisins	1	10
Streptococcus thermophilus	1	10
Zataria multiflora	1	10
Paeoniflorin	5	9
Kefir	3	8
Rose	4	8
Blueberry	4	7
Naringenin	4	7
Astragaloside	2	6
Cannabidiol	3	6
Carnosic Acid	3	6
Fisetin	3	6
Ginsenosides	3	6
Lycopene	3	6
Oleuropein	3	6
Beta-Caryophyllene	3	5
Chokeberry	3	5
Fish Oil	3	5
Flavonoids	3	5
Lactobacillus rhamnosus GG	3	5
Panax Notoginseng	3	5
Turmeric	3	5
Xanthohumol	3	5
Asiatic Acid	2	4
Beta Sitosterol	2	4
Betulinic acid	2	4
Bitter Melon	2	4
Camel Milk	1	4
Chlorogenic Acid	2	4
Citrulline	2	4
Crocin	2	4
Daidzein	2	4
Dragon Fruit	2	4
EGCG (Epigallocatechin gallate)	2	4
Fenugreek	1	4
Flaxseed Oil	2	4
Fucoidan	2	4
Gastrodin	2	4
Gingerol	2	4
Ginkgo biloba	2	4
Glycyrrhizin	2	4
Grape	2	4
Hawthorn	2	4
Honokiol	2	4
Hydrogen Water	2	4
Isoflavones	2	4
Lactobacillus paracasei	2	4
Mangiferin	2	4
Nobiletin	3	4
Phytate	1	4
Pine Needle	2	4
Procyanidin B2	2	4
Quercetin	2	4
Raspberry ketone	1	4
Red Sage	2	4
Saffron	2	4
Soy Protein	2	4
Stigmasterol	2	4
Ursolic Acid	2	4
Avocado	2	3
Black Tea	2	3
Cryptoxanthin	2	3
Ginger	2	3
Moringa oleifera	2	3
Silibinin	2	3
Tetrahydrocurcumin	2	3
Allicin	1	2
Alpha-Lipoic Acid	1	2
Apricot	1	2
Banaba	1	2
Bergamot orange	1	2
Bile salts	1	2
Bisdemethoxycurcumin	1	2
Caffeine	1	2
Catechin	1	2
Cherry: All Varieties	1	2
Chinese Skullcap	1	2
Cinnamon	1	2
Cocoa Butter	1	2
Codonopsis lanceolata	1	2
Cordyceps Militaris	1	2
Cranberry	1	2
D-Limonene	1	2
Diosgenin	1	2
Diosmin	1	2
Dryobalanops aromatica	1	2
Enterodiol	1	2
Eucalyptus	1	2
FOS (Fructooligosaccharides)	1	2
Fermented Foods and Beverages	1	2
Ferulic acid	1	2
Fructose	1	2
Galacto-oligosaccharides	1	2
Garlic: Aged	1	2
Genipin	1	2
Ginseng	1	2
Ginseng (American)	1	2
Goji	1	2
Gymnema Sylvestre	1	2
Hesperidin	1	2
Honeydew (melon)	1	2
Hops	1	2
Hu Zhang (Polygonum cuspidatum)	1	2
Lactobacillus casei: Shirota	1	2
Lactobacillus plantarum	1	2
Lactobacillus probiotics	1	2
Lignans	1	2
Loquat	1	2
Loquat Seeds	1	2
Luteolin	1	2
MSM (Methylsulfonylmethane)	1	2
Mangosteen	1	2
Medium Chain Triglycerides	1	2
Mukitake mushroom	1	2
Mulberry	1	2
Olive leaf extract	1	2
Onion	1	2
Parthenolide	1	2
Pau D'Arco	1	2
Pectin	1	2
Phyllanthus emblica	1	2
Phyllanthus urinaria	1	2
Pistachio nut	1	2
Pomegranate Peel	1	2
Pomegranate flower	1	2
Protein Supplement	1	2
Puerarin	1	2
Pumpkin Seeds	1	2
Pycnogenol (Pine Bark)	1	2
Red Cabbage	1	2
Red Yeast Rice	1	2
Reishi Mushroom	1	2
Rosemary	1	2
Rutin	1	2
SAMe (S-adenosylmethionine)	1	2
Schisandra	1	2
Seaweed: Brown	1	2
Secoisolariciresinol diglucoside (SDG)	1	2
Selenium	1	2
Sesamin	1	2
Squash: Butternut	1	2
Star Fruit	1	2
Thymoquinone	1	2
Tomato	1	2
Vaccenic acid	1	2
Virgin Coconut Oil	1	2
Vitamin E: Gamma-tocotrienol	1	2
Whey	1	2
Wogonin	1	2
Xanthones	1	2
Yerba Mate	1	2
Arctigenin	1	1
Blackberry	1	1
Dihydrocurcumin	1	1
Fish	1	1
Fucoxanthin	1	1
Lychee	1	1
Milk Thistle	1	1
Mugwort	1	1
Nuts	1	1
Punicalagin	1	1
Red Wine Extract	1	1
Strawberry	1	1
Tanshinone IIA	1	1
Thistle	1	1
Walnut	1	1
Yacón	1	1

Name	AC	CK
Fructose	25	90
Tamoxifen	6	52
High Fructose Corn Syrup	15	43
Bisphenol A	6	38
Sugar Sweetened Beverages	2	30
Insulin	3	14
Monosodium Glutamate (MSG)	5	10
Trans Fatty Acids	4	10
Glyphosate	3	7
Hydrogenated Oil	2	4
Irinotecan	2	3
Bisphenol S	1	2
Roundup (herbicide)	1	2
Sugary soda	1	2
Amiodarone	1	1
Methotrexate	1	1
Retinyl palmitate	1	1

Name	AC	CK
Exercise	7	57
Dietary Modification: Mediterranean Diet	4	31
Dietary Modification: Low Carbohydrate/Ketogenic	1	20
Breastfeeding	1	10
Exercise: Aerobic	1	10
Integrative Medicine	1	10
Lifestyle Changes: Positive	1	10
Acupuncture	1	2
Dietary Modification: Low Glycemic Diet	1	1
Dietary Modification: Wheat/Gluten Free	1	1

Name	AC	CK	Focus
Western Diet	8	17

Silymarin has positive efficacy to reduce transaminases levels in NAFLD patients.Nov 30, 2017

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[+]

A dietary intervention consisting of a Mediterranean diet could delay or slow down the natural progression of NAFL.Jan 22, 2017

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Pubmed Data : Minerva Med. 2018 Dec ;109(6):418-428. Epub 2018 Sep 13. PMID: 30221912

Article Published Date : Nov 30, 2018

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids, Probiotics

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic, Interferon Gamma Reducer, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Berberis extract can be used as a supplementary medication in treating NAFLD.Jan 31, 2015

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Pubmed Data : Hepat Mon. 2015 Feb ;15(2):e25067. Epub 2015 Feb 5. PMID: 25788958

curcumin supplementation can improve serum levels of inflammatory cytokines in subjects with NAFLD.Feb 29, 2020

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Pubmed Data : Complement Ther Med. 2020 Mar ;49:102322. Epub 2020 Jan 21. PMID: 32147075

Article Published Date : Feb 29, 2020

Study Type : Human Study

Additional Links

Substances : Curcuminoids

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Pubmed Data : World J Gastroenterol. 2011 Jul 28 ;17(28):3335-41. PMID: 21876622

Article Published Date : Jul 28, 2011

Study Type : Human Study

Additional Links

Diseases : Abdominal Obesity (Midsection Fat), Fatty Liver

Additional Keywords : Diseases that are Linked

[+]

Flaxseed oil in the context of a weight loss program ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease.Jan 28, 2020

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Pubmed Data : Br J Nutr. 2020 Jan 29:1-24. Epub 2020 Jan 29. PMID: 31992372

Article Published Date : Jan 28, 2020

Study Type : Human Study

Additional Links

Substances : Flaxseed

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

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Pubmed Data : Int J Food Sci Nutr. 2016 Jun ;67(4):461-9. Epub 2016 Mar 17. PMID: 26983396

Article Published Date : May 31, 2016

Study Type : Human Study

Additional Links

Substances : Flaxseed

Diseases : Insulin Resistance, Liver Fibrosis, Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Integrative Medicine, Lifestyle Changes: Positive

Pharmacological Actions : Anti-Fibrotic, Enzyme Inhibitors, Hepatoprotective

Additional Keywords : Significant Treatment Outcome

[+]

Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.Feb 28, 2019

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Pubmed Data : Med Hypotheses. 2019 Mar ;124:40-41. Epub 2019 Feb 4. PMID: 30798914

Article Published Date : Feb 28, 2019

Study Type : Human Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Nonalcoholic fatty liver disease (NAFLD)

Problem Substances : High Fructose Corn Syrup

[+]

Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.Dec 31, 2015

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Pubmed Data : Adv Biomed Res. 2016 ;5:2. Epub 2016 Jan 27. PMID: 26955623

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Pubmed Data : Liver Int. 2019 Mar 29. Epub 2019 Mar 29. PMID: 30924602

Article Published Date : Mar 28, 2019

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Nonalcoholic fatty liver disease (NAFLD)

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

[+]

Higher intake and serum levels of most carotenoids were associated with lower odds of having NAFLD.May 16, 2019

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Pubmed Data : Hepatology. 2010 Jun;51(6):1961-71. PMID: 20301112

Article Published Date : Jun 01, 2010

Study Type : Human Study

Additional Links

Diseases : Fatty Liver

Problem Substances : Fructose, High Fructose Corn Syrup

[+]

Increasing nutritional fiber results in reduced serum ZO levels, reduced liver enzymes and improved hepatic steatosis in patients with NAFLDNov 17, 2018

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Pubmed Data : Nutrients. 2018 Nov 18 ;10(11). Epub 2018 Nov 18. PMID: 30453660

Article Published Date : Nov 17, 2018

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Pubmed Data : J Ginseng Res. 2016 Jul ;40(3):203-10. Epub 2015 Aug 4. PMID: 27616896

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Pubmed Data : J Clin Res Pediatr Endocrinol. 2015 Jun 5 ;7(2):121-7. PMID: 26316434

Article Published Date : Jun 04, 2015

Study Type : Human Study

Additional Links

Substances : Polyunsaturated Fatty Acids (PUFAs)

Diseases : Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Hepatoprotective

[+]

Additional Keywords : Risk Reduction, Significant Treatment Outcome

[+]

Olive oil consumption has an ameliorative effect in non-alcoholic fatty liver disease.Apr 21, 2009

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Pubmed Data : World J Gastroenterol. 2009 Apr 21;15(15):1809-15. PMID: 19370776

Article Published Date : Apr 21, 2009

Study Type : Human Study

Additional Links

Substances : Olive Oil

Diseases : Fatty Liver, Insulin Resistance

Therapeutic Actions : Dietary Modification: Mediterranean Diet

Pharmacological Actions : Antioxidants, Glucagon Like peptide 1 (GLP-1) Up-regulation, Glucose transporter-2 (GLUT2) expression up-regulation, Insulin Sensitizers, Interleukin-6 Downregulation, NF-kappaB Inhibitor

[+]

Pantethine appears to improve fatty liver and hypertriglyceridemia.Jan 01, 2000

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Pubmed Data : J Atheroscler Thromb. 2000;7(1):55-8. PMID: 11425046

Article Published Date : Jan 01, 2000

Study Type : Human Study

Additional Links

Substances : Pantethine

Diseases : Fatty Liver, Hepatic Steatosis, Liver: Fatty, Triglycerides: Elevated

[+]

Pro- and prebiotic effects on oxidative stress and inflammatory markers in non-alcoholic fatty liver disease.Dec 31, 2017

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Pubmed Data : PLoS One. 2016 ;11(6):e0157515. Epub 2016 Jun 10. PMID: 27284686

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Nonalcoholic fatty liver disease (NAFLD), Vitamin D Deficiency

Additional Keywords : Risk Factors, Risk Reduction

[+]

Serum carotenoids are inversely associated with prevalence of NAFLD in middle aged and elderly Chinese.Dec 31, 2014

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Pubmed Data : AJR Am J Roentgenol. 2003 Jan;180(1):129-34. PMID: 12490491

Article Published Date : Jan 01, 2003

Study Type : Human Study

Additional Links

Diseases : Fatty Liver

Additional Keywords : Drug: Tamoxifen

Problem Substances : Tamoxifen

Adverse Pharmacological Actions : Hepatotoxic

[+]

Tamoxifen treatment for breast cancer may result in fatty liver.Nov 01, 2000

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Pubmed Data : Oncol Rep. 2000 Nov-Dec;7(6):1299-304. PMID: 11032933

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Pubmed Data : J Agric Food Chem. 2016 Sep 28 ;64(38):7104-13. Epub 2016 Sep 19. PMID: 27584700

Article Published Date : Sep 27, 2016

Study Type : Animal Study

Additional Links

Substances : Allicin

Diseases : Alcohol Toxicity , Fatty Liver, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Alcohol Toxicity, Allicin, Anti-Inflammatory Agents, Fatty Liver, Inflammation, oxidative stress

[+]

Allium fistulosum attenuates the development of NAFLD.Mar 31, 2018

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Pubmed Data : Nutr Res Pract. 2018 Apr ;12(2):110-117. Epub 2018 Mar 22. PMID: 29629027

Article Published Date : Mar 31, 2018

Study Type : Animal Study

Additional Links

Substances : Onion

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

Additional Keywords : Plant Extracts

[+]

Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease.Sep 13, 2019

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Pubmed Data : Int J Mol Med. 2018 Dec ;42(6):3047-3064. Epub 2018 Sep 14. PMID: 30221679

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Pubmed Data : PLoS One. 2017 ;12(1):e0169685. Epub 2017 Jan 12. PMID: 28081181

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Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:256-267. Epub 2018 Oct 17. PMID: 30340105

Article Published Date : Nov 30, 2018

Study Type : Animal Study

Additional Links

Substances : Asiatic Acid

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, NF-kappaB Inhibitor

[+]

Astaxanthin and vitamin E effectively improved hepatic gene expression.Mar 07, 2017

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Pubmed Data : Int J Mol Sci. 2017 Mar 8 ;18(3). Epub 2017 Mar 8. PMID: 28282876

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[+]

Pubmed Data : Drug Res (Stuttg). 2018 May 2. Epub 2018 May 2. PMID: 29719880

Article Published Date : May 01, 2018

Study Type : Animal Study

Additional Links

Substances : Hawthorn

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

[+]

Camel milk could provide a natural way to protect against NAFLD induced by a high-fat diet.Dec 31, 2012

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Pubmed Data : BMC Complement Altern Med. 2013 ;13:264. Epub 2013 Oct 13. PMID: 24119413

Chicory polysaccharides attenuate high-fat diet induced non-alcoholic fatty liver disease.Oct 14, 2018

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Pubmed Data : Int J Biol Macromol. 2018 Oct 15 ;118(Pt A):886-895. Epub 2018 Jun 28. PMID: 29964102

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Pubmed Data : J Nutr Biochem. 2020 May 22 ;83:108426. Epub 2020 May 22. PMID: 32559586

Article Published Date : May 21, 2020

Study Type : Animal Study

Additional Links

Substances : Citrus Peel , Orange: Mandarin

Diseases : Hepatic Steatosis, Inflammation, Liver Damage, Nonalcoholic fatty liver disease (NAFLD), Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation

[+]

Coadministration of epigallocatechin-3-gallate and caffeine in low dose ameliorates obesity and nonalcoholic fatty liver disease in obese rats.Feb 10, 2019

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Pubmed Data : Phytother Res. 2019 Feb 11. Epub 2019 Feb 11. PMID: 30746789

Article Published Date : Feb 10, 2019

Study Type : Animal Study

Additional Links

Substances : Caffeine, EGCG (Epigallocatechin gallate)

Diseases : Nonalcoholic fatty liver disease (NAFLD), Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Anti-Obesity Agents

[+]

Cocoa butter has a protective effect against alcoholic fatty liver in mice. Mar 01, 2008

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Pubmed Data : J Nutr. 2008 Mar;138(3):497-501. PMID: 18287356

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Pubmed Data : J Nutr Sci. 2019 ;8:e15. Epub 2019 Apr 22. PMID: 31037218

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Coffee

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective

Additional Keywords : Gut-liver axis

[+]

Combination of luteolin and lycopene effectively protect against nonalcoholic fatty liver disease.Jun 19, 2020

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Pubmed Data : Life Sci. 2020 Jun 20 ;256:117990. Epub 2020 Jun 20. PMID: 32574665

Article Published Date : Jun 19, 2020

Study Type : Animal Study

Additional Links

Substances : Luteolin, Lycopene

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor

[+]

Combination of probiotics and Salvia miltiorrhiza polysaccharide alleviates hepatic steatosis. Dec 02, 2019

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Pubmed Data : Lipids Health Dis. 2019 Jan 8 ;18(1):11. Epub 2019 Jan 8. PMID: 30621686

Article Published Date : Jan 07, 2019

Study Type : Animal Study

Additional Links

Substances : Crocin

Diseases : Hepatic Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

[+]

Crocus sativus has a protective action against non-alcoholic fatty liver disease in diabetic rats.Apr 30, 2017

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Anti Therapeutic Actions : Western Diet

[+]

Dietary isoliquiritigenin at a low dose ameliorates insulin resistance and NAFLD in diet-induced obesity.Oct 21, 2018

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Pubmed Data : Int J Mol Sci. 2018 Oct 22 ;19(10). Epub 2018 Oct 22. PMID: 30360437

[+]

Ecklonia cava treatment ameliorated hepatic steatosis by inhibiting inflammation and improving lipid metabolism.Dec 31, 2014

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Pubmed Data : Zhonghua Gan Zang Bing Za Zhi. 2017 Dec 20 ;25(12):927-933. PMID: 29325294

Article Published Date : Dec 19, 2017

Study Type : Animal Study

Additional Links

Substances : FOS (Fructooligosaccharides), Lactobacillus paracasei

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Effects of probiotic yogurt consumption on metabolic factors in individuals with nonalcoholic fatty liver disease.Nov 30, 2014

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Pubmed Data : J Dairy Sci. 2014 Dec ;97(12):7386-93. Epub 2014 Oct 11. PMID: 25306266

Article Published Date : Nov 30, 2014

Study Type : Animal Study

Additional Links

Substances : Probiotics, Yoghurt

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

Additional Keywords : Risk Reduction

[+]

EGCG inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.Sep 01, 2008

Pubmed Data : Biomed Res Int. 2015 ;2015:296207. Epub 2015 Apr 27. PMID: 26000287

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Banaba, Eucalyptus

Diseases : High Fructose Diet, Liver Disease, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses.Sep 19, 2017

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Pubmed Data : Sci Rep. 2017 Sep 20 ;7(1):11977. Epub 2017 Sep 20. PMID: 28931917

Article Published Date : Sep 19, 2017

Study Type : Animal Study

Additional Links

Diseases : Endotoxemia, Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective

[+]

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Microbiol. 2017 ;8:2271. Epub 2017 Nov 17. PMID: 29204141

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Pubmed Data : PLoS One. 2017 ;12(6):e0175406. Epub 2017 Jun 20. PMID: 28632732

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Pubmed Data : J Diabetes. 2009 Dec;1(4):278-87. Epub 2009 Jul 21. PMID: 20923528

Article Published Date : Dec 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Fatty Liver, Fructose-Induced Toxicity , Insulin Resistance, Liver Stress: Fructose-Induced, Nonalcoholic fatty liver disease (NAFLD)

Problem Substances : Fructose

Adverse Pharmacological Actions : Hepatotoxic

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View the Evidence: 646 Abstracts with Fatty Liver Research

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Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.Dec 31, 2019

Physical activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD.May 03, 2016

Polyunsaturated fatty acids supplementation can improve liver steatosis and liver functions.Dec 22, 2016

Silymarin has positive efficacy to reduce transaminases levels in NAFLD patients.Nov 30, 2017

Studies on coffee and NAFLD suggest that coffee consumption could have a protective role on fibrosis.Mar 29, 2016

The consumption of sugar-sweetened beverages has a dose-dependent effect on the risk of NAFLD.Jun 20, 2019

The systematic review and meta-analysis support that probiotics are superior to placebo in NAFLD patients.Dec 31, 2018

These results found a significantly decreased risk of NAFLD among coffee drinkers and significantly decreased risk of liver fibrosis.Nov 06, 2016

This meta-analysis supports a positive significant association between higher consumption of sugar sweetened beverages and NAFLD.May 13, 2018

Vitamin E significantly improved liver function and histologic changes in patients with NAFLD/NASH.Jun 30, 2015

8 weeks of provision of a diet low in free sugar content compared with usual diet resulted in significant improvement in hepatic steatosis.Jan 21, 2019

A 12-week aerobic exercise program reduces hepatic fat accumulation and insulin resistance in obese, Hispanic adolescents.Jan 31, 2010

A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients. Apr 30, 2015

A dietary intervention consisting of a Mediterranean diet could delay or slow down the natural progression of NAFL.Jan 22, 2017

A higher dietary vitamin C intake might help reduce the risk of non-alcoholic fatty liver disease.Dec 31, 2015

A low-carbohydrate, ketogenic diet improves fatty liver disease. Feb 01, 2007

A nutraceutical formula containing berberine, chlorogenic acid, and tocotrienols was found to improve a large number of metabolic and liver parameters in overweight subjects.Mar 28, 2015

Alternate-day fasting appears to be an effective diet therapy for individuals with NAFLD that can achieve weight loss and improvement of dyslipidaemia.Dec 17, 2019

Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.Oct 24, 2019

An improved diet is particularly important for individuals with a high genetic risk for NAFLD.Mar 27, 2018

Artichoke leaf extracts have benefits in the management of NASH.Dec 31, 2015

Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.Nov 30, 2018

Berberis extract can be used as a supplementary medication in treating NAFLD.Jan 31, 2015

Calcium plus calcitriol supplementation for 12 weeks may be potentially effective for biochemical parameters in NAFLD patients. Sep 27, 2016

Chlorella vulgaris supplementation have therapeutic value in patients with non-alcoholic fatty liver disease.Oct 31, 2012

Cocoa polyphenols improve endothelial function via Nox2 down-regulation in NASH patients.Nov 12, 2017

Coffee use is associated with lower levels of fatty liver. Feb 18, 2010

Combined phthalates influence on glucose and lipid metabolism may increase the possibility for NAFLD and insulin resistance development.Dec 05, 2019

Consumption of fruits that are high in antioxidants could represent a useful means to improve the antioxidant status of NAFLD.Jul 13, 2016

Consumption of hibiscus sabdariffa extracts reduced obesity, abdominal fat, serum FFA and improved liver steatosis.Mar 31, 2014

Consumption of Nigella sativa can reduce the inflammatory biomarkers in patients with NAFLD.May 31, 2019

CoQ10 supplement at a dosage of 100 mg could be effective for improving the systemic inflammation and biochemical variables in NAFLD.Jul 08, 2015

Curcumin prevented the development of immunological alterations in NAFLD.Dec 31, 2016

curcumin supplementation can improve serum levels of inflammatory cytokines in subjects with NAFLD.Feb 29, 2020

Delta-tocotrienol was safe, and it effectively improved aminotransferase levels and inflammatory and oxidative stress markers in patients with NAFLD.Dec 31, 2017

DHA supplementation improves liver steatosis in children with NAFLD. Oct 31, 2013

Diets with a higher intake of nuts may be associated with a decreased risk of NAFLD.Sep 03, 2019

Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity.Mar 14, 2017

Earlier feeding habits might affect the clinical expression of non-alcoholic fatty liver disease from 3 to 18 years later, with an apparent drug-like preventive effect of breastfeeding.Oct 01, 2009

Effect of vitamin D supplementation on various parameters in non-alcoholic fatty liver disease patients.Apr 30, 2019

Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease.Jun 30, 2018

Electroacupuncture and aerobic interval training exercise are potent modalities that improve liver functions in people with Nonalcoholic fatty liver disease.Oct 28, 2019

EPA increases adiponectin secretion in rodent models of obesity and human obese subjects, possibly through the improvement of the inflammatory changes in obese adipose tissue.Sep 01, 2007

Excessive dietary fructose consumption appears to contribute to metabolic syndrome and non-alcholic fatty liver disease. Jun 01, 2008

Exercise overcomes skeletal muscle insulin resistance. Aug 01, 2011

Fatty infiltration of the liver is correlated with amount of abdominal fat.Jul 28, 2011

Flaxseed oil in the context of a weight loss program ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease.Jan 28, 2020

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.Feb 28, 2019

Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.Dec 31, 2015

Garlic powder supplementation improved risk factors of NAFLD. May 31, 2020

Genistein can reduce insulin resistance, oxidative and inflammatory indices along with improvement in fat metabolism in patients with NAFLD.May 31, 2017

Genistein inhibits nonalcoholic fatty liver disease.Nov 01, 2007

Green tea extract therapy resulted in significant improvement in metabolic, chemical, inflammatory and radiological parameters of NAFLD patients.Jun 30, 2017

Gynostemma pentaphyllum is an effective adjunct treatment to diet therapy for patients with nonalcoholic fatty liver disease.May 01, 2006

Hesperidin supplementation accompanied with lifestyle modification is superior to lifestyle modification alone in management of NAFLD.Jun 30, 2019

High intake of magnesium may be associated with reduced risks of fatty liver disease and prediabetes.Apr 01, 2018

High levels of urinary BPA were associated with NAFLD in a nationally representative sample of adults in the US.Mar 28, 2019

Higher intake and serum levels of most carotenoids were associated with lower odds of having NAFLD.May 16, 2019

Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease.Apr 10, 2019

Inclusion of dried grapes in diet was beneficial in NAFLD patients with non-significant fibrosis.Nov 08, 2016

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease.Jun 01, 2010

Increasing nutritional fiber results in reduced serum ZO levels, reduced liver enzymes and improved hepatic steatosis in patients with NAFLDNov 17, 2018

Intestinal permeability is associated with visceral adiposity in healthy women. Aug 18, 2011

Ketogenic, hypocaloric diet improves nonalcoholic steatohepatitis.Feb 29, 2020

Korean red ginseng might be effective in reducing pro-inflammatory cytokines and fatigue in overweight patients with NAFLD.Jun 30, 2016

Lactobacillus bulgaricus and Streptococcus thermophilus improve liver aminotransferases levels in patients with nonalcoholic fatty liver disease.Sep 01, 2011

Lifetime alcohol consumption with up to 13 units per week is associated with lower fibrosis stage in NAFLD. Sep 20, 2016

Maintenance of high cardiorespiratory fitness and stability of body weight are critical public health considerations for the treatment of NAFLD.Jul 20, 2016

n-3 PUFA treatment is safe and efficacious in obese children with NAFLD and can improve ultrasonographic findings and the elevated transaminase levels.Jun 04, 2015

N. sativa seed oil seems to be safe and improve liver steatosis and injury and blood levels of triglycerides, LDL-C and HDL-C in the NAFLD patients.Apr 23, 2019

National Health and Nutrition Examination Surveys data collected from 1988 to 2008 show that the prevalence of major causes of CLD remained stable, except for NAFLD, which increased steadily, along with the prevalence of metabolic conditions. Jun 01, 2011

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View the Evidence:
646 Abstracts with Fatty Liver Research