Lipopolysaccharide-Induced Toxicity

Name	AC	CK
Curcumin	43	59
Ginsenosides	27	39
Flavonoids	14	28
Vitamin C	9	25
Polyphenols	9	24
Resveratrol	16	23
DHA (Docosahexaenoic Acid)	3	22
Pomegranate	2	20
Dandelion	14	17
Tanshinone IIA	11	15
Fermented Foods and Beverages	3	14
Honokiol	3	14
Isoflavones	3	14
Probiotics	3	14
Puerarin	9	13
Strawberry	4	13
Melatonin	5	12
Berberine	7	11
Vitamin D	2	11
Bacillus coagulans	1	10
Bilberry	1	10
Lactobacillus Acidophilus	1	10
Myricetin	7	10
Stilbenes	7	10
Yoghurt	1	10
Asiatic Acid	7	9
Cannabidiol	6	9
Echinacea	3	9
Fucoidan	7	9
Ginger	5	9
Luteolin	6	9
Punicalagin	5	9
Sesamol	5	9
Sulforaphane	7	9
Thymoquinone	5	9
Astragaloside	5	8
Genipin	6	8
Astaxanthin	4	7
Citrus naringin	4	7
Rose	4	7
Rutin	4	7
Thymol	4	7
Verbascoside	5	7
Barley	3	6
Bifidobacterium Longum	3	6
Cannabis	4	6
EGCG (Epigallocatechin gallate)	5	6
Fisetin	4	6
Green Tea	3	6
Hops	3	6
Nigella sativa (aka Black Seed)	3	6
Paeoniflorin	4	6
Piperine	4	6
Shikonin	4	6
Zerumbone	3	6
Caffeic acid phenethyl ester	1	5
Cannabinoids	4	5
Citral	1	5
Delta-tetrahydrocannabinol (THC)	4	5
Hydroxytyrosol	3	5
Licorice	3	5
Lotus	5	5
Mulberry	3	5
Naringenin	3	5
Nobiletin	3	5
Panax Notoginseng	3	5
Parthenolide	4	5
Piceatannol	4	5
Quercetin	4	5
Red Sage	3	5
Silibinin	3	5
Adlay	4	4
Bay leaf	3	4
Blue Honeysuckle	2	4
Chrysanthemum Indicum	3	4
Diosgenin	2	4
False Black Pepper	2	4
Ferulic acid	2	4
Garlic	2	4
Gastrodin	3	4
Geraniol	2	4
Ginseng (Siberian)	2	4
Huperzine	2	4
Isoliquiritigenin	2	4
Japanese cypress	2	4
Lactobacillus helveticus	2	4
Lactobacillus plantarum	2	4
Lupeol	2	4
Lycopene	2	4
Mangiferin	3	4
Mangosteen	3	4
Mussel: Green-lipped (Perna canaliculus)	2	4
Pine Needle	3	4
Pterostilbene	3	4
Purslane	2	4
Rosemaric Acid	2	4
Sesamin	2	4
Soy	2	4
Toona sinensis	3	4
Vitexins	3	4
Agrimony	2	3
Allicin	2	3
Anthocyanins	2	3
Apigenin	3	3
Ashwagandha	2	3
Bee Venom	3	3
Celery	2	3
Chrysin	3	3
Cinnamaldehyde	2	3
Coenzyme Q10	2	3
Flaxseed	2	3
Fucoxanthin	2	3
Gingerol	2	3
Ginkgo biloba	2	3
Hemp Seed	2	3
Hesperidin	2	3
Krill	2	3
Loquat Leaves	3	3
Neem	2	3
Phloretin	2	3
Prickly Pear Cactus	3	3
Salvia miltiorrhiza	2	3
Sea buckthorn	2	3
Spikenard	3	3
Tangeretin	2	3
Turmeric	3	3
Ubiquinol	3	3
Vanillin	3	3
Xanthohumol	2	3
Acai	1	2
Acorus calamus	1	2
Aduki bean	1	2
African Basil	1	2
Aloe Vera	1	2
Amygdalin	1	2
Arctigenin	1	2
Arginine	1	2
Bael	1	2
Bai Zhu	2	2
Belladonna	1	2
Beta-glucan	1	2
Bisdemethoxycurcumin	1	2
Black Pepper	1	2
Black Tea	1	2
Blueberry	2	2
Bromelain	2	2
Buckwheat	1	2
Capparis spinosa (caper)	1	2
Centella asiatica	1	2
Cocoa	2	2
Coffee	1	2
Cordyceps sinensis	1	2
Corn Silk	1	2
Curry Leaves	1	2
Damnacanthal	1	2
Diallyl sulfide	1	2
Ellagic Acid	1	2
Emodin	1	2
Fish Oil	1	2
Flaxseed Oil	1	2
Garden Cress (Lepidium sativum)	1	2
Gardenia	1	2
Genistein	2	2
Glucosamine	1	2
Gotu Kola	2	2
Grape Seed Extract	1	2
Hibiscus sabdariffa	1	2
Histidine	1	2
Honey	1	2
Hydrogen Water	1	2
Indole-3-Carbinol	1	2
Isoquercitrin	1	2
Justicia gendarussa	2	2
Lactobacillus casei	1	2
Lactobacillus gasseri	1	2
Lactobacillus reuteri	1	2
Lithium	1	2
MSM (Methylsulfonylmethane)	2	2
Magnesium Sulfate	1	2
Manuka Honey	2	2
Modified Citrus Pectin	1	2
Mushrooms: All	2	2
Noni	1	2
P-Coumaric Acid	1	2
Palmitoylethanolamide	1	2
Patchouli	1	2
Perillaldehyde	1	2
Phyllanthus amarus	2	2
Pine Bark Extract	1	2
Pine Cone	2	2
Piperlongumine	1	2
Polyunsaturated Fatty Acids (PUFAs)	1	2
Potato	1	2
Propolis: Brazillian	1	2
Pycnogenol (Pine Bark)	2	2
Radish	1	2
Raspberry	1	2
Reishi Mushroom	2	2
Riboflavin (Vitamin B-2)	1	2
Rosemary	2	2
Rosmarinic acid	1	2
Saffron	1	2
Sage	1	2
Saw Palmetto	1	2
Selenium	1	2
Spirulina	1	2
Sprouts	1	2
Stevia	1	2
Stigmasterol	1	2
Sweet Potato: Purple	1	2
Thuja	1	2
Turmerones	1	2
Vitamin B-12	1	2
Vitamin B-12: Hydroxocobalamin	1	2
Whey	1	2
Zataria multiflora	1	2
6-Shogaol	1	1
Acacia catechu	1	1
Amygdalin (laetrile)	1	1
Andrographis	1	1
Antrodia camphorata	1	1
Apocynin	1	1
Apple Pectin	1	1
Artesunate	1	1
Astragalus	1	1
Ayahuasca	1	1
Baicalein	1	1
Barley Grass	1	1
Bee Propolis	1	1
Benzyl isothiocyanate	1	1
Beta Sitosterol	1	1
Beta-Caryophyllene	1	1
Beta-Elemene	1	1
Black Raspberry	1	1
Boron	1	1
Butterbur	1	1
Carnosic Acid	1	1
Catechin	1	1
Catechols	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chamomile	1	1
Cherry: All Varieties	1	1
Chicoric Acid	1	1
Cordyceps Militaris	1	1
Cryptoxanthin	1	1
Cucurbitacin B	1	1
Cucurbitacin E	1	1
Curcumin: Degradiation byproducts	1	1
Curcumin: Lipidated	1	1
Diosmin	1	1
Eucalyptus	1	1
Euphorbia peplus	1	1
False Daisy	1	1
Flowers	1	1
Frankincense	1	1
Garlic: Aged	1	1
Guggul	1	1
Horseradish	1	1
Hyaluronic Acid	1	1
Jujube	1	1
Juniper	1	1
Knema laurina	1	1
Kombucha Tea	1	1
Lactobacillus rhamnosus	1	1
Lactobacillus rhamnosus GG	1	1
Lauric acid	1	1
Lavender: Essential Oil	1	1
Lignans	1	1
Ligustrazine	1	1
Lion's Mane (Hericium Erinaceus)	1	1
Longan	1	1
Maple Syrup	1	1
Matairesinol	1	1
Medicinal Mushrooms	1	1
Methionine	1	1
Moringa oleifera	1	1
Oak	1	1
Panax Ginseng	1	1
Passion Flower	1	1
Peppermint	1	1
Perilla	1	1
Persimmon	1	1
Phenethyl isothiocyanate	1	1
Plantago	1	1
Polyacetylenes	1	1
Pomegranate Peel	1	1
Pomegranate flower	1	1
Prebiotics	1	1
Prunella vulgaris	1	1
Purple Carrots	1	1
Red Cabbage	1	1
Red Clover	1	1
Rhubarb	1	1
Rice: Black	1	1
Royal Jelly	1	1
Saccharomyces Boulardii	1	1
Seaweed: Brown	1	1
Sessile Joyweed	1	1
Sour Cherry	1	1
Syrian rue	1	1
Tea	1	1
Thistle	1	1
Thyme	1	1
Tualang Honey	1	1
Urolithin A	1	1
Vitamin E: Gamma-tocotrienol	1	1
Vitex negundo	1	1
Willow Bark	1	1
Xanthones	1	1

Name	AC	CK
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	3	3
Aluminum	1	2
Antibiotics	1	2
Aspirin	1	2
Chlorpyrifos	1	2
Fluoxetine (trade name Prozac)	1	2
Oseltamivir (trade name Tamiflu)	1	2
Pesticides	1	2
Selective Serotonin Reuptake Inhibitors (SSRIs)	1	2
Ibuprofen	1	1

Name	AC	CK
Exercise	1	10
Exercise: Running	1	10
Homeopathic Treatment	1	2
Microbiota Transfer Therapy	1	2
Ultrasound therapy	1	2
Fasting/Caloric Restriction	1	1

Name	AC	CK	Focus
Western Diet	1	2

Additional Keywords : Microbiota

[+]

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID: 25948780

[+]

There is a measurable systemic inflammatory response in first trimester pregnancy failure.Jan 31, 2012

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Pubmed Data : Hum Reprod. 2012 Feb ;27(2):349-57. Epub 2011 Nov 29. PMID: 22131390

Article Published Date : Jan 31, 2012

Study Type : Human Study

Additional Links

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Miscarriage

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Food Chem Toxicol. 2018 Feb 16. Epub 2018 Feb 16. PMID: 29458159

Article Published Date : Feb 15, 2018

Study Type : Human In Vitro

Additional Links

Substances : Strawberry

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

These results showed for the first time a clear and a dose-dependent protective effect of strawberry extract on LPS-induced damage in HDF cell line.Jan 20, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2017 Jan 21 ;22(1). Epub 2017 Jan 21. PMID: 28117711

Article Publish Status : This is a free article. Click here to read the complete article.

Anti-inflammatory and antioxidant properties of black mulberry in a Model of LPS-induced sepsis.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:5048031. Epub 2018 Nov 7. PMID: 30524657

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID: 27455313

Centella asiantica has a protective effect against acute liver injury in mice. Feb 17, 2010

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Pubmed Data : Phytomedicine. 2010 Feb 17. Epub 2010 Feb 17. PMID: 20171071

Article Published Date : Feb 17, 2010

Study Type : Animal Study

Additional Links

Substances : Centella asiatica

Diseases : Chemically-Induced Liver Damage, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Hepatoprotective

[+]

Chilean white strawberry aqueous extract favours the normalization of oxidative and inflammatory responses after a liver injury induced by LPS.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:320136. Epub 2015 Sep 17. PMID: 26457108

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Strawberry

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation.Aug 01, 2007

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Pubmed Data : J Neurochem. 2007 Aug;102(3):761-72. Epub 2007 May 4. PMID: 17488274

Article Published Date : Aug 01, 2007

Study Type : Animal Study

Additional Links

Substances : Lithium

Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Chrysanthemum indicum has a protective effect on acute lung injury induced by lipopolysaccharide.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mediators Inflamm. 2014 ;2014:246407. Epub 2014 Aug 25. PMID: 25214712

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Chrysanthemum Indicum

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Clorpyrifos significantly altered the gut microbiota composition.May 31, 2016

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Pubmed Data : Chemosphere. 2016 Jun ;153:287-93. Epub 2016 Mar 26. PMID: 27018521

Article Published Date : May 31, 2016

Study Type : Animal Study

Additional Links

Diseases : Dysbiosis, Lipopolysaccharide-Induced Toxicity, Pesticide Toxicity

Additional Keywords : Microbiota

Problem Substances : Chlorpyrifos, Pesticides

[+]

Constituents of Moringa oleifera seeds regulate expression of Th17-relevant cytokines and ameliorate TPA-induced psoriasis-like skin lesions.Dec 09, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2018 Dec 10 ;23(12). Epub 2018 Dec 10. PMID: 30544700

Article Published Date : Dec 09, 2018

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Pubmed Data : J Agric Food Chem. 2017 Feb 1 ;65(4):759-768. Epub 2017 Jan 17. PMID: 28064493

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Corn Silk

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Crocus sativus, Serenoa repens and Pinus massoniana extracts modulate inflammatory response in isolated rat prostate challenged with LPS.Jun 30, 2017

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Pubmed Data : J Biol Regul Homeost Agents. 2017 Jul-Sep,;31(3):531-541. PMID: 28889734

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2014 ;9(1):e86117. Epub 2014 Jan 24. PMID: 24475077

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2016 Dec 3 ;16(1):501. Epub 2016 Dec 3. PMID: 27912738

Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection.Sep 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int Immunopharmacol. 2016 May ;34:53-59. Epub 2016 Feb 24. PMID: 26921732

Article Published Date : Apr 30, 2016

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Ginsenoside Rg3 attenuates lipopolysaccharide-induced acute lung injury.Dec 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2018 ;9:850. Epub 2018 Aug 2. PMID: 30116194

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Ginsenoside Rg3 attenuates microglia activation following systemic lipopolysaccharide treatment in mice.Dec 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2012 ;35(9):1546-52. PMID: 22975507

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Ginsenoside Rg3 was effective in ameliorating depressive-like behavior induced by immune activation.Aug 15, 2017

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Pubmed Data : J Agric Food Chem. 2017 Aug 16 ;65(32):6861-6869. Epub 2017 Aug 7. PMID: 28762741

Article Published Date : Aug 15, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Neuroinflammation. 2017 04 4 ;14(1):74. Epub 2017 Apr 4. PMID: 28376889

Article Published Date : Jan 03, 2017

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract

Diseases : Gout, Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Proanthocyanidins

[+]

Green mussel extract decreases the production of cytokines associated with inflammation.Dec 01, 2008

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Pubmed Data : Eur Ann Allergy Clin Immunol. 2008 Dec;40(4):148-53. PMID: 19227651

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Pubmed Data : Homeopathy. 2004 Oct;93(4):193-8. PMID: 15532698

Pubmed Data : J Med Food. 2018 Oct ;21(10):1009-1015. PMID: 30334699

Article Published Date : Sep 30, 2018

Study Type : Animal Study

Additional Links

Substances : Hops

Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Hepatoprotective, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Humulus japonicus inhibits the progression of Alzheimer's disease.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Med. 2017 Jan ;39(1):21-30. Epub 2016 Nov 16. PMID: 28004107

Article Published Date : Dec 31, 2016

Study Type : Transgenic Animal Study

Additional Links

Substances : Hops

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Huperzine A inhibits CCL2 production in experimental autoimmune encephalomyelitis.Jun 30, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Immunopathol Pharmacol. 2013 Jul-Sep;26(3):757-64. PMID: 24067473

Article Published Date : Jun 30, 2013

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Huperzine

Diseases : Lipopolysaccharide-Induced Toxicity, Multiple Sclerosis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function.Sep 18, 2016

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Pubmed Data : Neurosci Lett. 2016 Sep 19 ;631:70-8. Epub 2016 Jul 9. PMID: 27400829

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Agric Food Chem. 2017 Feb 1 ;65(4):846-857. Epub 2017 Jan 24. PMID: 28081600

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Mangosteen

Diseases : Lipopolysaccharide-Induced Toxicity, Psoriasis

Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-23 Downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Isoliquiritigenin attenuates adipose tissue inflammation in vitro and adipose tissue fibrosis.Mar 14, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Additional Keywords : Drug: Indomethacin, Plant Extracts, Xanthones

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Eur J Pharmacol. 2018 Mar 5. Epub 2018 Mar 5. PMID: 29518393

Article Published Date : Mar 04, 2018

Study Type : Animal Study

Additional Links

Substances : Naringenin

Diseases : Lipopolysaccharide-Induced Toxicity, Memory Disorders

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Anti-Inflammatory Agents, Lipopolysaccharide-Induced Toxicity, Memory Disorders, Naringenin

[+]

Naringenin ameliorates LPS-induced acute lung injury through its anti-oxidative and anti-inflammatory activity.Aug 31, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Mol Med. 2017 Dec ;40(6):1932-1940. Epub 2017 Oct 10. PMID: 29039495

Article Published Date : Nov 30, 2017

Study Type : Animal Study

Additional Links

Substances : Neem

Diseases : Chronic Obstructive Pulmonary Disease, Lipopolysaccharide-Induced Toxicity, Smoking

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Nobiletin clearly restored the alveolar bone mass in a mouse experimental model for periodontitis by inhibiting LPS-induced bone resorption.Dec 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Portulaca oleracea extract dose-dependently displays anti-oxidant and anti-inflammatory activity against lipopolysaccharide-induced acute lung injury.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2019 Jan 1 ;24(1). Epub 2019 Jan 1. PMID: 30609661

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Purslane

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Portulaca oleracea L. prevents lipopolysaccharide-induced passive avoidance learning and memory impairments.Jan 31, 2017

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Pubmed Data : Physiol Behav. 2017 Feb 1 ;169:69-73. Epub 2016 Nov 24. PMID: 27889331

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Pubmed Data : J Am Coll Nutr. 2018 Oct 11:1-9. Epub 2018 Oct 11. PMID: 30307792

Article Published Date : Oct 10, 2018

Study Type : Animal Study

Additional Links

Substances : Bifidobacterium Longum , Lactobacillus helveticus

Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Probiotic mixture of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 attenuates hippocampal apoptosis induced by lipopolysaccharide.Dec 10, 2018

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Pubmed Data : Int Microbiol. 2018 Dec 11. Epub 2018 Dec 11. PMID: 30810993

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Pubmed Data : Mol Cell Biochem. 2018 Jan 10. Epub 2018 Jan 10. PMID: 29322353

Article Published Date : Jan 09, 2018

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Radish seeds and sinapic acid may be attractive materials for treating inflammatory disorders caused by endotoxins.Nov 30, 2014

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Pubmed Data : Int Immunopharmacol. 2014 Dec ;23(2):726-34. PMID: 25467201

Article Published Date : Nov 30, 2014

Study Type : Animal Study

Additional Links

Substances : Radish

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Significant Treatment Outcome

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Resveratrol has a protective effect on acute lung injury induced by lipopolysaccharide in mice.Mar 01, 2011

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Pubmed Data : Anat Rec (Hoboken). 2011 Mar;294(3):527-32. Epub 2011 Jan 31. PMID: 21284090

Article Published Date : Mar 01, 2011

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Infection, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor

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Article Publish Status : This is a free article. Click here to read the complete article.

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Bilberry has anti-inflammatory properties.Sep 01, 2010

Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.Dec 06, 2006

Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia.May 16, 2018

Consumption of pomegranate extract decreased endotoxemia in overweight-obese individuals by reshaping the gut microbiota.May 31, 2018

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

DHA diet supplementation attenuated cytokine production after exercise.Aug 31, 2016

Honokiol protects pulmonary microvascular endothelial barrier against lipopolysaccharide-induced ARDS.Sep 30, 2018

Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.Feb 27, 2016

Lithium can increase brain 17-hydroxy-DHA formation, indicating a new and potentially important therapeutic action of lithium.May 01, 2010

Moderate running exercise prevents excessive immune system activation.Feb 18, 2019

Probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation.Jan 01, 2009

Puerarin acts as an anti-inflammatory agent by blocking NF-kappaB signalling.Jul 31, 2010

There is a measurable systemic inflammatory response in first trimester pregnancy failure.Jan 31, 2012

Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.Dec 31, 2013

Vitamin D partially reversed the effect of lipopolysaccharide induced imbalances and protected patients with T2DM and DNU.Aug 28, 2016

Caffeic acid phenethyl ester could be effective for treating of periodontal diseases.Nov 06, 2016

Citral inhibits LPS-induced inflammatory response via activating PPAR-γ which attenuates NF-κB activation.Dec 10, 2015

Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.Aug 31, 2012

Strawberry extracts efficiently counteract inflammatory stress induced by the endotoxin lipopolysaccharide.Feb 15, 2018

These results showed for the first time a clear and a dose-dependent protective effect of strawberry extract on LPS-induced damage in HDF cell line.Jan 20, 2017

"Fucoidan enhances the survival and sustains the number of splenic dendritic cells in mouse endotoxemia."Mar 31, 2011

2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevents lipopolysaccharide-induced depressive-like behaviours.Dec 31, 2016

6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment.Oct 31, 2018

A hydro-alcoholic extract of nigella sativa reduced the LPS-induced sickness behaviors in rats.Dec 31, 2015

A traditional Korean fermented soybean food exhibits anti-inflammatory activity which may have therapeutic value in allergic conditions such as asthma and atopic dermatitis. Sep 01, 2008

A water extract of Taraxacum mongolicum had a protective effect on lipopolysaccharide induced acute lung injury in mice.Jun 19, 2015

A. calamus prevented from memory deficits and stress through controlling oxidative stress and inflammation processes.Dec 31, 2017

Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.Mar 14, 2017

Acteoside has a protective and therapeutic effect on LPS-induced immunological liver injury in mice.Oct 31, 2009

Acteoside has beneficial effects on lipopolysaccharide-induced inflammation in acute lung injury.May 31, 2015

Aegle marmelos fruit extract attenuates Helicobacter pylori Lipopolysaccharide induced oxidative stress.Oct 18, 2015

AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.Sep 30, 2014

Agrimony exhibits anti-inflammatory activity, substantiating its traditional uses for inflammation and allergic diseases. Jan 01, 2010

Allicin attenuates lipopolysaccharide‑induced acute lung injury.Mar 06, 2018

Alliin ameliorates DSS-induced ulcerative colitis and inhibits the inflammatory responses in LPS-stimulated RAW264.7 cells.Mar 29, 2017

Amygdalin reduces lipopolysaccharide-induced chronic liver injury.Nov 30, 2019

An extract of Stevia rebaudiana leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury.Oct 31, 2017

Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.Nov 27, 2017

Anthocyanin-rich fractions from red raspberries attenuate inflammation both in vitro and in vivo.Dec 31, 2013

Anti-inflammatory and antioxidant properties of black mulberry in a Model of LPS-induced sepsis.Dec 31, 2017

Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol.Sep 04, 2015

Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.Apr 14, 2016

Antibiotic-induced depletion of murine microbiota induces mild inflammation.Sep 30, 2015

Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.Dec 31, 2016

Anti‑inflammatory effects of Panax notoginseng saponins ameliorate acute lung injury induced by oleic acid and lipopolysaccharide.Aug 31, 2014

Arctigenin has anti-inflammatory and antioxidative effects on LPS-induced acute lung injury.Jul 31, 2015

Ascorbic acid attenuated the inflammatory response and fibrosis in the lungs of rats treated with lipopolysaccharide.Dec 31, 2018

Ascorbic acid attenuates lipopolysaccharide-induced acute lung injury.May 31, 2011

Ascorbic acid modulates in vitro the function of macrophages from mice with endotoxic shock.Dec 31, 1999

Asiatic acid inhibits lipopolysaccharide-induced acute lung injury in mice.Sep 30, 2016

Astaxanthin ameliorates lipopolysaccharide-induced neuroinflammation, oxidative stress and memory dysfunction.Feb 17, 2019

Astaxanthin ameliorates the behavioural deficits of prenatal maternal LPS-exposure.Dec 31, 2015

Astaxanthin prevents against lipopolysaccharide-induced acute lung injury and sepsis.Dec 31, 2018

Astragaloside IV alleviates lipopolysaccharide-induced acute kidney injury.Mar 21, 2017

Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.Nov 30, 2016

Astragaloside IV suppresses inflammatory mediator production in synoviocytes and collagen‑induced arthritic rats.Mar 31, 2016

Attenuating effect of Ginsenoside Rb1 on LPS-induced lung injury in rats.Dec 31, 2013

Barley sprouts have a protective effect against alcohol-induced liver injury.Jul 20, 2016

Bay leaf contains compounds which inhibit LPS-activated nitric oxide production and which induce heat shock protein. Apr 21, 2000

Beneficial effects of tea water extracts on the body weight and gut microbiota in C57BL/6J mice fed with a high-fat diet.May 06, 2019

Berberine alleviates endothelial glycocalyx degradation and promotes glycocalyx restoration in LPS-induced ARDS.Oct 07, 2018

Berberine can be a potential therapeutic agent for osteoclast-related bone diseases.Mar 03, 2019

Berberine hydrochloride can provide mice robust protection from LPS-induced mastitis.Dec 31, 2017

Beta glucan inhibits experimental periodontal disease possibly through steering the T helper Th1/Th2 balance towards Th1 and T regulatory responses. Apr 01, 2005

Black Adzuki bean attenuates high-fat diet-induced colon inflammation.Mar 31, 2017

Brazilian propolis contains some natural products that can decrease thrombotic tendencies in mice.Aug 31, 2016

Buckwheat sprouts have an anti-inflammatory effect in lipopolysaccharide-activated human colon cancer cells and mice.Dec 01, 2008

By promoting fertility and eliminating oxidative stress and inflammation, Punicalagin may be a useful nutrient for the treatment of infertility.Jan 11, 2016

C. obtusa essential oil may constitute a novel source of anti-inflammatory treatments. Jun 30, 2013

Cannabidiol has a neuroprotective effect in endotoxin-induced uveitis. Jan 01, 2008

Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.Aug 14, 2000

Cannabidiol might become a useful therapeutic tool for the attenuation and treatment of inflammatory lung diseases.Jan 31, 2015

Lipopolysaccharide-Induced Toxicity

View the Evidence:
678 Abstracts with Lipopolysaccharide-Induced Toxicity Research