Lipopolysaccharide-Induced Toxicity

Name	AC	CK
Curcumin	51	68
Flavonoids	32	50
Ginsenosides	30	44
Vitamin C	14	35
Polyphenols	14	34
Resveratrol	19	30
DHA (Docosahexaenoic Acid)	3	22
Berberine	14	21
Paeoniflorin	13	20
Pomegranate	2	20
Puerarin	11	20
Dandelion	15	18
Fermented Foods and Beverages	7	18
Paeonol	11	18
Probiotics	5	18
Tanshinone IIA	14	18
Vitamin D	5	17
Honokiol	4	16
Sulforaphane	12	16
Astragaloside	11	15
Fucoidan	11	15
Isoflavones	4	15
Luteolin	11	15
Stilbenes	8	15
Astaxanthin	8	14
Safflower	10	14
Cannabidiol	9	13
Honeysuckle	8	13
Hydroxytyrosol	8	13
Melatonin	6	13
Strawberry	4	13
Fisetin	8	12
Licorice	8	12
Oridonin	8	12
Pterostilbene	7	12
Bee Venom	7	11
Echinacea	4	11
Eriodictyol	6	11
Ginger	7	11
Isoliquiritigenin	6	11
Myricetin	8	11
Quercetin	8	11
Sesamol	6	11
Asiatic Acid	8	10
Bacillus coagulans	1	10
Bilberry	1	10
Lactobacillus Acidophilus	1	10
Olive	1	10
Olive Oil	1	10
Punicalagin	6	10
Thymoquinone	6	10
Yoghurt	1	10
Citrus naringin	6	9
Lycopene	5	9
Patchouli	5	9
Zerumbone	5	9
Biochanin A	5	8
EGCG (Epigallocatechin gallate)	7	8
Genipin	6	8
Lactoferrin	6	8
Lotus	7	8
Nigella sativa (aka Black Seed)	4	8
Piperine	5	8
Shikonin	6	8
Blue Honeysuckle	4	7
Carvacrol	4	7
Citral	2	7
Genistein	6	7
Green Tea	4	7
Hops	4	7
Mangiferin	6	7
Mulberry	5	7
NAC (N-acetyl-L-cysteine)	5	7
P-Coumaric Acid	4	7
Peony	5	7
Red Sage	4	7
Rose	4	7
Rutin	4	7
Thymol	4	7
Verbascoside	5	7
Apigenin	6	6
Barley	3	6
Bifidobacterium Longum	3	6
Cannabis	4	6
Cordyceps sinensis	3	6
Crocin	4	6
Emodin	4	6
Frankincense	5	6
Oleocanthal	2	6
Panax Notoginseng	4	6
Phyllanthus amarus	4	6
Reishi Mushroom	6	6
Sea buckthorn	4	6
Selenium	3	6
Sesamin	3	6
Adlay	5	5
Anthocyanins	4	5
Ashwagandha	3	5
Blueberry	4	5
Caffeic acid phenethyl ester	1	5
Cannabinoids	4	5
Celery	3	5
Chrysin	4	5
Delta-tetrahydrocannabinol (THC)	4	5
Diosgenin	3	5
Elderberry	1	5
Ellagic Acid	3	5
Formononetin	3	5
Fucoxanthin	4	5
Gastrodin	4	5
Guduchi	1	5
Kaempferol	3	5
Krill	3	5
Lactobacillus rhamnosus GG	3	5
Naringenin	3	5
Nobiletin	3	5
Parthenolide	4	5
Phellinus Linteus	5	5
Piceatannol	4	5
Pine Needle	4	5
Purslane	3	5
Silibinin	3	5
Toona sinensis	4	5
Walnut	4	5
Zinc	3	5
Aloe Vera	2	4
Bay leaf	3	4
Black Tea	2	4
Burdock	2	4
Chrysanthemum Indicum	3	4
Eucalyptus	3	4
False Black Pepper	2	4
Ferulic acid	2	4
Garlic	2	4
Geraniol	2	4
Ginkgo biloba	3	4
Ginseng (Siberian)	2	4
Hemp Seed	3	4
Honey	2	4
Huperzine	2	4
Japanese cypress	2	4
Kiwifruit	3	4
Lactobacillus helveticus	2	4
Lactobacillus plantarum	2	4
Ligustrazine	4	4
Lupeol	2	4
Mangosteen	3	4
Mussel: Green-lipped (Perna canaliculus)	2	4
Phloretin	3	4
Red Clover	3	4
Rosemaric Acid	2	4
Soy	2	4
Tangeretin	3	4
Vanillin	4	4
Vitexins	3	4
Zataria multiflora	2	4
Agrimony	2	3
Allicin	2	3
Amygdalin (laetrile)	2	3
Angelica	3	3
Astragalus	2	3
Bai Zhu	3	3
Bee Propolis	3	3
Beta-Caryophyllene	2	3
Bitter Melon	2	3
Butterbur	2	3
Carnosic Acid	2	3
Chokeberry	2	3
Cinnamaldehyde	2	3
Coenzyme Q10	2	3
Crocetin	2	3
Diosmetin	2	3
Diosmin	2	3
Flaxseed	2	3
Gingerol	2	3
Glycyrrhizin	2	3
Gotu Kola	3	3
Hesperidin	2	3
Hydrangea	2	3
Loquat Leaves	3	3
Moringa oleifera	2	3
Neem	2	3
Omega-3 Fatty Acids	2	3
Polyunsaturated Fatty Acids (PUFAs)	2	3
Poria cocos	3	3
Prickly Pear Cactus	3	3
Radish	2	3
Rosmarinic acid	2	3
Salvia miltiorrhiza	2	3
Schisandra	2	3
Seaweed: Brown	3	3
Spikenard	3	3
Sweet Potato: Purple	2	3
Turmeric	3	3
Ubiquinol	3	3
Whey	2	3
Xanthohumol	2	3
Acai	1	2
Acorus calamus	1	2
Aduki bean	1	2
African Basil	1	2
Alpha Linolenic Acid	1	2
Amygdalin	1	2
Arctigenin	1	2
Arginine	1	2
Babchi	2	2
Bael	1	2
Belladonna	1	2
Bergamot	1	2
Beta-glucan	1	2
Bisdemethoxycurcumin	1	2
Black Pepper	1	2
Bromelain	2	2
Buckwheat	1	2
Butyrate	1	2
Caffeine	1	2
Capparis spinosa (caper)	1	2
Cardamonin	1	2
Carnosine	1	2
Catechin	2	2
Catechols	2	2
Celastrol	1	2
Centella asiatica	1	2
Chaste Tree (Chasteberry)	1	2
Chrysanthemum Morifolium	2	2
Clove	1	2
Cocoa	2	2
Coffee	1	2
Cordyceps Militaris	2	2
Corn Silk	1	2
Cucurbitacin E	2	2
Curry Leaves	1	2
Damnacanthal	1	2
Diallyl sulfide	1	2
Dogwood	2	2
Fiber	1	2
Fish Oil	1	2
Flaxseed Oil	1	2
Gallic Acid	1	2
Gamma-Oryzanol	1	2
Garden Cress (Lepidium sativum)	1	2
Gardenia	1	2
Ginseng	1	2
Ginseng (Korean)	1	2
Glucosamine	1	2
Gold (nanoparticles)	1	2
Grape Seed Extract	1	2
Hibiscus	2	2
Hibiscus sabdariffa	1	2
Histidine	1	2
Hydrogen Water	1	2
Indole-3-Carbinol	1	2
Isoquercitrin	1	2
Isothiocyanates	1	2
Justicia gendarussa	2	2
Lactobacillus casei	1	2
Lactobacillus gasseri	1	2
Lactobacillus reuteri	1	2
Lactobacillus sakei	1	2
Lignans	2	2
Lion's Mane (Hericium Erinaceus)	2	2
Liquiritigenin	1	2
Lithium	1	2
MSM (Methylsulfonylmethane)	2	2
Magnesium Sulfate	1	2
Maitake Mushroom	2	2
Manuka Honey	2	2
Medicinal Mushrooms	2	2
Modified Citrus Pectin	1	2
Motherwort	2	2
Mushrooms: All	2	2
Noni	1	2
Oleuropein	1	2
Orthosiphon	2	2
Palmitoylethanolamide	1	2
Perilla	2	2
Perillaldehyde	1	2
Pine Bark Extract	1	2
Pine Cone	2	2
Piperlongumine	1	2
Plantago asiatica	1	2
Potato	1	2
Procyanidin B2	2	2
Propolis: Brazillian	1	2
Pycnogenol (Pine Bark)	2	2
Raspberry	1	2
Red Marine Algae	1	2
Riboflavin (Vitamin B-2)	1	2
Rosemary	2	2
Saffron	1	2
Sage	1	2
Saw Palmetto	1	2
Spirulina	1	2
Sprouts	1	2
Stevia	1	2
Stigmasterol	1	2
Thistle	2	2
Thuja	1	2
Turmerones	1	2
Urolithin A	2	2
Vitamin B-12	1	2
Vitamin B-12: Hydroxocobalamin	1	2
Vitamin B-6	1	2
White Mulberry	2	2
acetyl-11-keto-beta-boswellic acid	1	2
6-Shogaol	1	1
Acacia catechu	1	1
Almond	1	1
Andrographis	1	1
Antrodia camphorata	1	1
Apocynin	1	1
Apple	1	1
Apple Pectin	1	1
Artemisinin	1	1
Artesunate	1	1
Ayahuasca	1	1
Baicalein	1	1
Barley Grass	1	1
Benzyl isothiocyanate	1	1
Beta Sitosterol	1	1
Beta-Elemene	1	1
Black Raspberry	1	1
Blackberry	1	1
Boron	1	1
Carnosol	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chamomile	1	1
Cherry: All Varieties	1	1
Chicoric Acid	1	1
Chlorogenic Acid	1	1
Citric Acid	1	1
Coconut	1	1
Cryptoxanthin	1	1
Cucumber	1	1
Cucurbitacin B	1	1
Curcumin: Degradiation byproducts	1	1
Curcumin: Lipidated	1	1
Curcuminoids	1	1
Daidzein	1	1
Demethoxycurcumin	1	1
Eugenol	1	1
Euphorbia peplus	1	1
False Daisy	1	1
Fig	1	1
Flowers	1	1
Galactooligosaccharides	1	1
Garlic: Aged	1	1
Glycyrrhiza uralensis	1	1
Green Coffee Bean	1	1
Guggul	1	1
Hawthorn	1	1
Hazelnut	1	1
Horseradish	1	1
Horsetail	1	1
Hyaluronic Acid	1	1
Jujube	1	1
Juniper	1	1
Knema laurina	1	1
Kombucha Tea	1	1
Lactobacillus rhamnosus	1	1
Lauric acid	1	1
Lavender: Essential Oil	1	1
Linoleic acid	1	1
Longan	1	1
Macadamia	1	1
Maple Syrup	1	1
Matairesinol	1	1
Methionine	1	1
Mugwort	1	1
Myrrh	1	1
Nuts	1	1
Oak	1	1
Oligosaccharides	1	1
Panax Ginseng	1	1
Passion Flower	1	1
Peppermint	1	1
Persimmon	1	1
Phenethyl isothiocyanate	1	1
Pistachio nut	1	1
Plantago	1	1
Polyacetylenes	1	1
Pomegranate Peel	1	1
Pomegranate flower	1	1
Prebiotics	1	1
Prunella vulgaris	1	1
Purple Carrots	1	1
Quince	1	1
Red Cabbage	1	1
Rhubarb	1	1
Rice: Black	1	1
Royal Jelly	1	1
Saccharomyces Boulardii	1	1
Sessile Joyweed	1	1
Shiitake Mushroom	1	1
Sour Cherry	1	1
Syrian rue	1	1
Tea	1	1
Tetrahydrocurcumin	1	1
Thyme	1	1
Tualang Honey	1	1
Vitamin E: Gamma-tocotrienol	1	1
Vitex negundo	1	1
Wheat Germ	1	1
Willow Bark	1	1
Xanthones	1	1

Name	AC	CK
Insulin	1	5
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	3	3
Pesticides	2	3
Aluminum	1	2
Antibiotics	1	2
Aspirin	1	2
Chlorpyrifos	1	2
Diclofenac	1	2
Electronic Cigarettes	1	2
Fluoxetine (trade name Prozac)	1	2
Oseltamivir (trade name Tamiflu)	1	2
Selective Serotonin Reuptake Inhibitors (SSRIs)	1	2
Glyphosate	1	1
Heavy Metals	1	1
Ibuprofen	1	1

Name	AC	CK
Exercise	1	10
Exercise: Running	1	10
Microbiota Transfer Therapy	2	4
Homeopathic Treatment	1	2
Laser Treatment: Low-Level	1	2
Ultrasound therapy	1	2
Fasting/Caloric Restriction	1	1

Name	AC	CK
Electromagnetic Field Harms	1	5
Electromagnetic Radiation	1	5
Western Diet	2	4

Additional Keywords : Microbiota

[+]

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID: 25948780

Article Published Date : Jun 30, 2015

Study Type : Human Study

Additional Links

Substances : Bacillus coagulans

Diseases : C-Reactive Protein, Dysbiosis, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Microbiota

[+]

DHA diet supplementation attenuated cytokine production after exercise.Aug 31, 2016

Click here to read the entire abstract

Pubmed Data : J Physiol Biochem. 2016 Sep ;72(3):421-34. Epub 2016 May 2. PMID: 27139422

Article Published Date : Aug 31, 2016

Study Type : Human Study

Additional Links

Substances : DHA (Docosahexaenoic Acid)

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Additional Keywords : Plant Extracts

[+]

There is a measurable systemic inflammatory response in first trimester pregnancy failure.Jan 31, 2012

Click here to read the entire abstract

Pubmed Data : Hum Reprod. 2012 Feb ;27(2):349-57. Epub 2011 Nov 29. PMID: 22131390

Article Published Date : Jan 31, 2012

Study Type : Human Study

Additional Links

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Miscarriage

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mediators Inflamm. 2014 ;2014:426740. Epub 2014 Aug 1. PMID: 25253919

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Vitamin C

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress, Pneumonia

Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Vitamin D partially reversed the effect of lipopolysaccharide induced imbalances and protected patients with T2DM and DNU.Aug 28, 2016

Click here to read the entire abstract

Pubmed Data : Genet Mol Res. 2016 Aug 29 ;15(3). Epub 2016 Aug 29. PMID: 27706649

Click here to read the entire abstract

Pubmed Data : Inflammation. 2015 Dec 11. Epub 2015 Dec 11. PMID: 26658749

Article Published Date : Dec 10, 2015

Study Type : Human In Vitro

Additional Links

Substances : Citral

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Elderberry and elderflower extracts inhibit nitric oxide production in lipopolysaccharide-activated macrophages.Mar 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:6659240. Epub 2021 Feb 27. PMID: 33728025

Article Published Date : Dec 31, 2020

Study Type : Human In Vitro

Additional Links

Substances : Puerarin

Diseases : Atherosclerosis, Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Resveratrol could be a prime candidate in ameliorating dysfunctioning adipose tissue induced by inflammatory stimulation.Jan 01, 2016

Click here to read the entire abstract

Pubmed Data : PLoS One. 2016 ;11(7):e0159747. Epub 2016 Jul 20. PMID: 27438462

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2017 Jan 21 ;22(1). Epub 2017 Jan 21. PMID: 28117711

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Poult Sci. 2020 Jul ;99(7):3411-3427. Epub 2020 Apr 15. PMID: 32616235

Article Published Date : Jun 30, 2020

Study Type : Animal Study

Additional Links

Substances : Genistein

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Gastrointestinal Agents, Gastroprotective

[+]

Effects of Oridonin on growth performance and oxidative stress in broilers challenged with lipopolysaccharide.Sep 30, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2019 May 28 ;24(11). Epub 2019 May 28. PMID: 31141940

Article Published Date : May 27, 2019

Study Type : Animal Study

Additional Links

Substances : Honokiol

Diseases : Depression, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Antidepressant-like effects of β-caryophyllene on restraint plus stress-induced depression.Feb 16, 2020

Click here to read the entire abstract

Pubmed Data : Behav Brain Res. 2020 Feb 17 ;380:112439. Epub 2019 Dec 17. PMID: 31862467

[+]

Astaxanthin ameliorates the behavioural deficits of prenatal maternal LPS-exposure.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Neurosci. 2016 ;17(1):11. Epub 2016 Feb 8. PMID: 26856812

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress, Prenatal Chemical Exposures

Pharmacological Actions : Antioxidants

[+]

Astaxanthin ameliorates the lipopolysaccharides-induced subfertility.Jun 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mar Drugs. 2021 Jun 17 ;19(6). Epub 2021 Jun 17. PMID: 34204220

Article Published Date : Jun 16, 2021

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Immunomodulatory, Nrf2 activation

[+]

Astaxanthin suppresses lipopolysaccharide‑induced myocardial injury.Aug 18, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Kaohsiung J Med Sci. 2020 Oct 22. Epub 2020 Oct 22. PMID: 33089927

Article Published Date : Oct 21, 2020

Study Type : Animal Study

Additional Links

Substances : Astragaloside

Diseases : Lipopolysaccharide-Induced Toxicity, Pre-Eclampsia

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor

[+]

Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.Nov 30, 2016

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2016 Dec ;41:47-55. Epub 2016 Nov 2. PMID: 27816726

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID: 27455313

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Pubmed Data : Food Funct. 2019 May 7. Epub 2019 May 7. PMID: 31062778

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Carnosic acid protects against lipopolysaccharide-induced acute lung injury in mice.Oct 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2019 Nov ;18(5):3707-3714. Epub 2019 Sep 23. PMID: 31611929

Article Published Date : Oct 31, 2019

Study Type : Animal Study

Additional Links

Substances : Carnosic Acid

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:320136. Epub 2015 Sep 17. PMID: 26457108

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Strawberry

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2020 Aug ;45(16):3938-3944. PMID: 32893592

Article Published Date : Jul 31, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Honeysuckle

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Constituents of Moringa oleifera seeds regulate expression of Th17-relevant cytokines and ameliorate TPA-induced psoriasis-like skin lesions.Dec 09, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2018 Dec 10 ;23(12). Epub 2018 Dec 10. PMID: 30544700

Article Published Date : Dec 09, 2018

Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome.Jan 09, 2020

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Pubmed Data : Inflamm Res. 2020 Jan 10. Epub 2020 Jan 10. PMID: 31925528

Article Published Date : Jan 09, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Crocin

Diseases : Lipopolysaccharide-Induced Toxicity, Respiratory Distress Syndrome

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Crocus sativus, Serenoa repens and Pinus massoniana extracts modulate inflammatory response in isolated rat prostate challenged with LPS.Jun 30, 2017

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Pubmed Data : J Biol Regul Homeost Agents. 2017 Jul-Sep,;31(3):531-541. PMID: 28889734

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Pubmed Data : Clin Exp Immunol. 2006 Aug;145(2):313-21. PMID: 16879252

Article Published Date : Aug 01, 2006

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Endotoxemia, Lipopolysaccharide-Induced Toxicity, Liver Damage, Oxidative Stress

Pharmacological Actions : Hepatoprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Curcumin and selenium can hinder the progression and severity of liver injury during acute inflammatory episodes.Oct 24, 2019

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Pubmed Data : Biol Trace Elem Res. 2019 Oct 25. Epub 2019 Oct 25. PMID: 31654258

[+]

Engeletin alleviates lipopolysaccharide-induced endometritis.Aug 09, 2016

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Pubmed Data : J Agric Food Chem. 2016 Aug 10 ;64(31):6171-8. Epub 2016 Jul 28. PMID: 27411287

Article Published Date : Aug 09, 2016

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Endometritis, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Engeletin inhibits Lipopolysaccharide/d-galactosamine-induced liver injury.Jun 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Zhonghua Yi Xue Za Zhi. 2019 May 28 ;99(20):1582-1587. PMID: 31154727

Article Published Date : May 27, 2019

Study Type : Animal Study

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Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute

Therapeutic Actions : Microbiota Transfer Therapy

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

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Fermented barley extract effectively inhibited the propagation of inflammation by suppressing oxidative stress.Dec 31, 2010

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Pubmed Data : Biosci Biotechnol Biochem. 2011 ;75(10):1971-6. Epub 2011 Oct 7. PMID: 21979071

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Pubmed Data : Mol Neurobiol. 2019 Dec 12. Epub 2019 Dec 12. PMID: 31832973

Article Published Date : Dec 11, 2019

Study Type : Animal Study

Additional Links

Substances : Gallic Acid

Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Garden cress extracts have significant hepatoprotective activity in animals. Dec 02, 2016

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Pubmed Data : BMC Complement Altern Med. 2016 Dec 3 ;16(1):501. Epub 2016 Dec 3. PMID: 27912738

Article Published Date : Dec 02, 2016

Study Type : Animal Study

Additional Links

Substances : Garden Cress (Lepidium sativum)

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-10 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Dose Response, Plant Extracts

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Gastrodin attenuation of the inflammatory response in H9c2 cardiomyocytes involves inhibition of NF-κB and MAPKs activation.Apr 14, 2013

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Pubmed Data : Biochem Pharmacol. 2013 Apr 15 ;85(8):1124-33. Epub 2013 Jan 29. PMID: 23376120

Article Published Date : Apr 14, 2013

Study Type : Animal Study

Additional Links

Substances : Gastrodin

Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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View the Evidence: 1129 Abstracts with Lipopolysaccharide-Induced Toxicity Research

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Bilberry has anti-inflammatory properties.Sep 01, 2010

Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.Dec 06, 2006

Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia.May 16, 2018

Consumption of pomegranate extract decreased endotoxemia in overweight-obese individuals by reshaping the gut microbiota.May 31, 2018

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

DHA diet supplementation attenuated cytokine production after exercise.Aug 31, 2016

Extra virgin olive oil mitigates postprandial lipopolysaccharide-induced inflammation and oxidative stress.Mar 01, 2019

Honokiol protects pulmonary microvascular endothelial barrier against lipopolysaccharide-induced ARDS.Sep 30, 2018

Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.Feb 27, 2016

Lithium can increase brain 17-hydroxy-DHA formation, indicating a new and potentially important therapeutic action of lithium.May 01, 2010

Moderate running exercise prevents excessive immune system activation.Feb 18, 2019

Preeclampsia patients had gut microbiota dysbiosis and increased plasma lipopolysaccharide and trimethylamine-N-oxide levels.Dec 31, 2018

Probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation.Jan 01, 2009

Puerarin acts as an anti-inflammatory agent by blocking NF-kappaB signalling.Jul 31, 2010

There is a measurable systemic inflammatory response in first trimester pregnancy failure.Jan 31, 2012

Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.Dec 31, 2013

Vitamin D partially reversed the effect of lipopolysaccharide induced imbalances and protected patients with T2DM and DNU.Aug 28, 2016

50 Hz magnetic fields and lipopolysaccharides synergistically reduce cell viability in vitro.Jan 10, 2016

Alpha-bisobolol inhibits lipopolysaccharide-induced inflammation.Oct 01, 2011

Caffeic acid phenethyl ester could be effective for treating of periodontal diseases.Nov 06, 2016

Citral inhibits LPS-induced inflammatory response via activating PPAR-γ which attenuates NF-κB activation.Dec 10, 2015

Elderberry and elderflower extracts inhibit nitric oxide production in lipopolysaccharide-activated macrophages.Mar 08, 2017

Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction.Jan 10, 2017

Luteolin and apigenin derived glycosides from Alphonsea elliptica abrogate LPS-induced inflammatory responses in human plasma.Apr 19, 2021

Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.Aug 31, 2012

Oleocanthal inhibits catabolic and inflammatory mediators in LPS-activated human primary osteoarthritis chondrocytes.Dec 31, 2017

Plant polyphenols mitigate the pro-inflammatory and pro-oxidant adipocyte response to lipopolysaccharides.Jan 01, 2017

Puerarin may improve mitochondrial respiratory function and energy metabolism, increasing the vulnerability of HUVECs to an inflammatory state.Dec 31, 2020

Resveratrol could be a prime candidate in ameliorating dysfunctioning adipose tissue induced by inflammatory stimulation.Jan 01, 2016

Strawberry extracts efficiently counteract inflammatory stress induced by the endotoxin lipopolysaccharide.Feb 15, 2018

T. cordifolia dry leaf extracts possess antioxidant and anti-inflammatory properties.Jul 31, 2019

These results showed for the first time a clear and a dose-dependent protective effect of strawberry extract on LPS-induced damage in HDF cell line.Jan 20, 2017

α-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.Jan 01, 2014

Aloin suppresses lipopolysaccharide-induced acute lung injury by inhibiting NLRP3/NF-κB via activation of SIRT1 in mice.Jul 31, 2020

Dietary genistein supplementation protects against lipopolysaccharide-induced intestinal injury through altering transcriptomic profile.Jun 30, 2020

Effects of Oridonin on growth performance and oxidative stress in broilers challenged with lipopolysaccharide.Sep 30, 2016

Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response.Sep 30, 2020

Hydroxytyrosol ameliorates oxidative challenge and inflammatory response associated with lipopolysaccharide-mediated sepsis.Aug 24, 2020

Oleuropein protects against lipopolysaccharide-induced sepsis and alleviates inflammatory responses in mice.Jul 24, 2020

"Fucoidan enhances the survival and sustains the number of splenic dendritic cells in mouse endotoxemia."Mar 31, 2011

2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevents lipopolysaccharide-induced depressive-like behaviours.Dec 31, 2016

6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment.Oct 31, 2018

A frankincense extract displayed anti-inflammatory, anti-oxidative, and hepatoprotective effects.Dec 31, 2017

A hydro-alcoholic extract of nigella sativa reduced the LPS-induced sickness behaviors in rats.Dec 31, 2015

A traditional Korean fermented soybean food exhibits anti-inflammatory activity which may have therapeutic value in allergic conditions such as asthma and atopic dermatitis. Sep 01, 2008

A water extract of Taraxacum mongolicum had a protective effect on lipopolysaccharide induced acute lung injury in mice.Jun 19, 2015

A. calamus prevented from memory deficits and stress through controlling oxidative stress and inflammation processes.Dec 31, 2017

Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.Mar 14, 2017

Acteoside has a protective and therapeutic effect on LPS-induced immunological liver injury in mice.Oct 31, 2009

Acteoside has beneficial effects on lipopolysaccharide-induced inflammation in acute lung injury.May 31, 2015

Actinidia arguta extract attenuates inflammasome activation: Potential involvement in NLRP3 ubiquitination.Feb 28, 2018

Aegle marmelos fruit extract attenuates Helicobacter pylori Lipopolysaccharide induced oxidative stress.Oct 18, 2015

AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.Sep 30, 2014

Agrimony exhibits anti-inflammatory activity, substantiating its traditional uses for inflammation and allergic diseases. Jan 01, 2010

Allicin attenuates lipopolysaccharide‑induced acute lung injury.Mar 06, 2018

Alliin ameliorates DSS-induced ulcerative colitis and inhibits the inflammatory responses in LPS-stimulated RAW264.7 cells.Mar 29, 2017

Allyl isothiocyanate ameliorates dextran sodium sulfate-induced colitis.Jul 11, 2018

Alpha-linolenic acid protects against lipopolysaccharide-induced acute lung injury through anti-inflammatory and anti-oxidative pathways.Feb 17, 2020

Ameliorative effect of thymoquinone-loaded PLGA nanoparticles on chronic lung injury induced by repetitive intratracheal instillation of lipopolysaccharide.Dec 31, 2020

Amygdalin reduces lipopolysaccharide-induced chronic liver injury.Nov 30, 2019

An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties.May 31, 2007

An extract of Stevia rebaudiana leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury.Oct 31, 2017

An integrated network pharmacology and RNA-Seq approach for exploring the preventive effect of Lonicerae japonicae flos on LPS-induced acute lung injury.Sep 08, 2020

Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.Nov 27, 2017

Anthocyanin-rich fractions from red raspberries attenuate inflammation both in vitro and in vivo.Dec 31, 2013

Anti-inflammatory and antioxidant properties of black mulberry in a Model of LPS-induced sepsis.Dec 31, 2017

Anti-inflammatory effect of sulforaphane on LPS-stimulated RAW 264.7 cells and ob/ob mice.Oct 31, 2020

Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol.Sep 04, 2015

Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.Apr 14, 2016

Antibiotic-induced depletion of murine microbiota induces mild inflammation.Sep 30, 2015

Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.Dec 31, 2016

Antidepressant-like effect and mechanism of action of honokiol in lipopolysaccharide depression model.May 27, 2019

Lipopolysaccharide-Induced Toxicity

View the Evidence:
1129 Abstracts with Lipopolysaccharide-Induced Toxicity Research