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Lipopolysaccharide-Induced Toxicity
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309 Substances Researched for Lipopolysaccharide-Induced Toxicity
Name
AC
CK
Focus
Curcumin
43
59
Ginsenosides
27
39
Flavonoids
14
28
Vitamin C
9
25
Polyphenols
9
24
Resveratrol
16
23
DHA (Docosahexaenoic Acid)
3
22
Pomegranate
2
20
Dandelion
14
17
Tanshinone IIA
11
15
Fermented Foods and Beverages
3
14
Honokiol
3
14
Isoflavones
3
14
Probiotics
3
14
Puerarin
9
13
Strawberry
4
13
Melatonin
5
12
Berberine
7
11
Vitamin D
2
11
Bacillus coagulans
1
10
Bilberry
1
10
Lactobacillus Acidophilus
1
10
Myricetin
7
10
Stilbenes
7
10
Yoghurt
1
10
Asiatic Acid
7
9
Cannabidiol
6
9
Echinacea
3
9
Fucoidan
7
9
Ginger
5
9
Luteolin
6
9
Punicalagin
5
9
Sesamol
5
9
Sulforaphane
7
9
Thymoquinone
5
9
Astragaloside
5
8
Genipin
6
8
Astaxanthin
4
7
Citrus naringin
4
7
Rose
4
7
Rutin
4
7
Thymol
4
7
Verbascoside
5
7
Barley
3
6
Bifidobacterium Longum
3
6
Cannabis
4
6
EGCG (Epigallocatechin gallate)
5
6
Fisetin
4
6
Green Tea
3
6
Hops
3
6
Nigella sativa (aka Black Seed)
3
6
Paeoniflorin
4
6
Piperine
4
6
Shikonin
4
6
Zerumbone
3
6
Caffeic acid phenethyl ester
1
5
Cannabinoids
4
5
Citral
1
5
Delta-tetrahydrocannabinol (THC)
4
5
Hydroxytyrosol
3
5
Licorice
3
5
Lotus
5
5
Mulberry
3
5
Naringenin
3
5
Nobiletin
3
5
Panax Notoginseng
3
5
Parthenolide
4
5
Piceatannol
4
5
Quercetin
4
5
Red Sage
3
5
Silibinin
3
5
Adlay
4
4
Bay leaf
3
4
Blue Honeysuckle
2
4
Chrysanthemum Indicum
3
4
Diosgenin
2
4
False Black Pepper
2
4
Ferulic acid
2
4
Garlic
2
4
Gastrodin
3
4
Geraniol
2
4
Ginseng (Siberian)
2
4
Huperzine
2
4
Isoliquiritigenin
2
4
Japanese cypress
2
4
Lactobacillus helveticus
2
4
Lactobacillus plantarum
2
4
Lupeol
2
4
Lycopene
2
4
Mangiferin
3
4
Mangosteen
3
4
Mussel: Green-lipped (Perna canaliculus)
2
4
Pine Needle
3
4
Pterostilbene
3
4
Purslane
2
4
Rosemaric Acid
2
4
Sesamin
2
4
Soy
2
4
Toona sinensis
3
4
Vitexins
3
4
Agrimony
2
3
Allicin
2
3
Anthocyanins
2
3
Apigenin
3
3
Ashwagandha
2
3
Bee Venom
3
3
Celery
2
3
Chrysin
3
3
Cinnamaldehyde
2
3
Coenzyme Q10
2
3
Flaxseed
2
3
Fucoxanthin
2
3
Gingerol
2
3
Ginkgo biloba
2
3
Hemp Seed
2
3
Hesperidin
2
3
Krill
2
3
Loquat Leaves
3
3
Neem
2
3
Phloretin
2
3
Prickly Pear Cactus
3
3
Salvia miltiorrhiza
2
3
Sea buckthorn
2
3
Spikenard
3
3
Tangeretin
2
3
Turmeric
3
3
Ubiquinol
3
3
Vanillin
3
3
Xanthohumol
2
3
Acai
1
2
Acorus calamus
1
2
Aduki bean
1
2
African Basil
1
2
Aloe Vera
1
2
Amygdalin
1
2
Arctigenin
1
2
Arginine
1
2
Bael
1
2
Bai Zhu
2
2
Belladonna
1
2
Beta-glucan
1
2
Bisdemethoxycurcumin
1
2
Black Pepper
1
2
Black Tea
1
2
Blueberry
2
2
Bromelain
2
2
Buckwheat
1
2
Capparis spinosa (caper)
1
2
Centella asiatica
1
2
Cocoa
2
2
Coffee
1
2
Cordyceps sinensis
1
2
Corn Silk
1
2
Curry Leaves
1
2
Damnacanthal
1
2
Diallyl sulfide
1
2
Ellagic Acid
1
2
Emodin
1
2
Fish Oil
1
2
Flaxseed Oil
1
2
Garden Cress (Lepidium sativum)
1
2
Gardenia
1
2
Genistein
2
2
Glucosamine
1
2
Gotu Kola
2
2
Grape Seed Extract
1
2
Hibiscus sabdariffa
1
2
Histidine
1
2
Honey
1
2
Hydrogen Water
1
2
Indole-3-Carbinol
1
2
Isoquercitrin
1
2
Justicia gendarussa
2
2
Lactobacillus casei
1
2
Lactobacillus gasseri
1
2
Lactobacillus reuteri
1
2
Lithium
1
2
MSM (Methylsulfonylmethane)
2
2
Magnesium Sulfate
1
2
Manuka Honey
2
2
Modified Citrus Pectin
1
2
Mushrooms: All
2
2
Noni
1
2
P-Coumaric Acid
1
2
Palmitoylethanolamide
1
2
Patchouli
1
2
Perillaldehyde
1
2
Phyllanthus amarus
2
2
Pine Bark Extract
1
2
Pine Cone
2
2
Piperlongumine
1
2
Polyunsaturated Fatty Acids (PUFAs)
1
2
Potato
1
2
Propolis: Brazillian
1
2
Pycnogenol (Pine Bark)
2
2
Radish
1
2
Raspberry
1
2
Reishi Mushroom
2
2
Riboflavin (Vitamin B-2)
1
2
Rosemary
2
2
Rosmarinic acid
1
2
Saffron
1
2
Sage
1
2
Saw Palmetto
1
2
Selenium
1
2
Spirulina
1
2
Sprouts
1
2
Stevia
1
2
Stigmasterol
1
2
Sweet Potato: Purple
1
2
Thuja
1
2
Turmerones
1
2
Vitamin B-12
1
2
Vitamin B-12: Hydroxocobalamin
1
2
Whey
1
2
Zataria multiflora
1
2
6-Shogaol
1
1
Acacia catechu
1
1
Amygdalin (laetrile)
1
1
Andrographis
1
1
Antrodia camphorata
1
1
Apocynin
1
1
Apple Pectin
1
1
Artesunate
1
1
Astragalus
1
1
Ayahuasca
1
1
Baicalein
1
1
Barley Grass
1
1
Bee Propolis
1
1
Benzyl isothiocyanate
1
1
Beta Sitosterol
1
1
Beta-Caryophyllene
1
1
Beta-Elemene
1
1
Black Raspberry
1
1
Boron
1
1
Butterbur
1
1
Carnosic Acid
1
1
Catechin
1
1
Catechols
1
1
Chaga Mushroom (Inonotus obliquus)
1
1
Chamomile
1
1
Cherry: All Varieties
1
1
Chicoric Acid
1
1
Cordyceps Militaris
1
1
Cryptoxanthin
1
1
Cucurbitacin B
1
1
Cucurbitacin E
1
1
Curcumin: Degradiation byproducts
1
1
Curcumin: Lipidated
1
1
Diosmin
1
1
Eucalyptus
1
1
Euphorbia peplus
1
1
False Daisy
1
1
Flowers
1
1
Frankincense
1
1
Garlic: Aged
1
1
Guggul
1
1
Horseradish
1
1
Hyaluronic Acid
1
1
Jujube
1
1
Juniper
1
1
Knema laurina
1
1
Kombucha Tea
1
1
Lactobacillus rhamnosus
1
1
Lactobacillus rhamnosus GG
1
1
Lauric acid
1
1
Lavender: Essential Oil
1
1
Lignans
1
1
Ligustrazine
1
1
Lion's Mane (Hericium Erinaceus)
1
1
Longan
1
1
Maple Syrup
1
1
Matairesinol
1
1
Medicinal Mushrooms
1
1
Methionine
1
1
Moringa oleifera
1
1
Oak
1
1
Panax Ginseng
1
1
Passion Flower
1
1
Peppermint
1
1
Perilla
1
1
Persimmon
1
1
Phenethyl isothiocyanate
1
1
Plantago
1
1
Polyacetylenes
1
1
Pomegranate Peel
1
1
Pomegranate flower
1
1
Prebiotics
1
1
Prunella vulgaris
1
1
Purple Carrots
1
1
Red Cabbage
1
1
Red Clover
1
1
Rhubarb
1
1
Rice: Black
1
1
Royal Jelly
1
1
Saccharomyces Boulardii
1
1
Seaweed: Brown
1
1
Sessile Joyweed
1
1
Sour Cherry
1
1
Syrian rue
1
1
Tea
1
1
Thistle
1
1
Thyme
1
1
Tualang Honey
1
1
Urolithin A
1
1
Vitamin E: Gamma-tocotrienol
1
1
Vitex negundo
1
1
Willow Bark
1
1
Xanthones
1
1
10 Problem Substances Researched for Lipopolysaccharide-Induced Toxicity
Name
AC
CK
Focus
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
3
3
Aluminum
1
2
Antibiotics
1
2
Aspirin
1
2
Chlorpyrifos
1
2
Fluoxetine (trade name Prozac)
1
2
Oseltamivir (trade name Tamiflu)
1
2
Pesticides
1
2
Selective Serotonin Reuptake Inhibitors (SSRIs)
1
2
Ibuprofen
1
1
6 Therapeutic Actions Researched for Lipopolysaccharide-Induced Toxicity
Name
AC
CK
Focus
Exercise
1
10
Exercise: Running
1
10
Homeopathic Treatment
1
2
Microbiota Transfer Therapy
1
2
Ultrasound therapy
1
2
Fasting/Caloric Restriction
1
1
1 Problematic Actions Researched for Lipopolysaccharide-Induced Toxicity
Name
AC
CK
Focus
Western Diet
1
2
Research Articles
650
Cumulative Knowledge Score
1051
Overall Research Rating
EXCELLENT
View the Evidence:
932 Abstracts with Lipopolysaccharide-Induced Toxicity Research
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[+]
Bilberry has anti-inflammatory properties.
Sep 01, 2010
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID:
20119859
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.
Dec 06, 2006
Add to My Research
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2006 Dec 6;108(3):398-406. Epub 2006 Jun 2. PMID:
16824715
Article Published Date
: Dec 06, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Consumption of pomegranate decreases plasma lipopolysaccharide-binding protein levels, a marker of metabolic endotoxemia.
May 16, 2018
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 May 17. Epub 2018 May 17. PMID:
29770393
Article Published Date
: May 16, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Colorectal Cancer
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Consumption of pomegranate extract decreased endotoxemia in overweight-obese individuals by reshaping the gut microbiota.
May 31, 2018
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2018 Jun ;62(11):e1800160. Epub 2018 May 17. PMID:
29665619
Article Published Date
: May 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
C-Reactive Protein
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Microbiota
[+]
Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.
Jun 30, 2015
Add to My Research
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID:
25948780
Article Published Date
: Jun 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Bacillus coagulans
Diseases
:
C-Reactive Protein
,
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Microbiota
[+]
DHA diet supplementation attenuated cytokine production after exercise.
Aug 31, 2016
Add to My Research
Click here to read the entire abstract
Pubmed Data
: J Physiol Biochem. 2016 Sep ;72(3):421-34. Epub 2016 May 2. PMID:
27139422
Article Published Date
: Aug 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Extra virgin olive oil mitigates postprandial lipopolysaccharide-induced inflammation and oxidative stress.
Mar 01, 2019
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2019 Mar ;58(2):843-851. Epub 2018 May 16. PMID:
29766292
Article Published Date
: Mar 01, 2019
Study Type
: Human Study
Additional Links
Substances
:
Olive
,
Olive Oil
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidant
,
Antioxidant Effects
[+]
Honokiol protects pulmonary microvascular endothelial barrier against lipopolysaccharide-induced ARDS.
Sep 30, 2018
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2018 Oct 1 ;210:86-95. Epub 2018 Aug 29. PMID:
30171880
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study, Human In Vitro, Human Study
Additional Links
Substances
:
Honokiol
Diseases
:
Acute Respiratory Distress Syndrome
,
Lipopolysaccharide-Induced Toxicity
[+]
Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.
Feb 27, 2016
Add to My Research
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2016 Feb 28 ;115(4):567-75. Epub 2016 Jan 15. PMID:
26769562
Article Published Date
: Feb 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus Acidophilus
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interferon Gamma Reducer
,
Interleukin-10 upregulation
,
Interleukin-4 upregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Lithium can increase brain 17-hydroxy-DHA formation, indicating a new and potentially important therapeutic action of lithium.
May 01, 2010
Add to My Research
Click here to read the entire abstract
Pubmed Data
: J Lipid Res. 2010 May;51(5):1049-56. Epub 2009 Dec 29. PMID:
20040630
Article Published Date
: May 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Bipolar Disorder
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Moderate running exercise prevents excessive immune system activation.
Feb 18, 2019
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Physiol Behav. 2019 Feb 19. Epub 2019 Feb 19. PMID:
30794851
Article Published Date
: Feb 18, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Therapeutic Actions
:
Exercise: Running
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Preeclampsia patients had gut microbiota dysbiosis and increased plasma lipopolysaccharide and trimethylamine-N-oxide levels.
Dec 31, 2018
Add to My Research
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cell Infect Microbiol. 2019 ;9:409. Epub 2019 Dec 3. PMID:
31850241
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
,
Pre-Eclampsia
Additional Keywords
:
Risk Factors
[+]
Probiotic administration in the elderly normalises the response to endotoxin, and modulates activation markers in blood phagocytes, and therefore may help reduce low-grade chronic inflammation.
Jan 01, 2009
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2009;61(5):680-6. PMID:
19353762
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Probiotics
,
Yoghurt
Diseases
:
Aging
,
Endotoxemia
,
Immune Disorders: Low Immune Function
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Immunomodulatory
[+]
Puerarin acts as an anti-inflammatory agent by blocking NF-kappaB signalling.
Jul 31, 2010
Add to My Research
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2010 Aug ;107(2):637-42. Epub 2010 Mar 22. PMID:
20346059
Article Published Date
: Jul 31, 2010
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones
Diseases
:
Angina Pectoris
,
Atherosclerosis
,
C-Reactive Protein
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
There is a measurable systemic inflammatory response in first trimester pregnancy failure.
Feb 01, 2012
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Hum Reprod. 2012 Feb ;27(2):349-57. Epub 2011 Nov 29. PMID:
22131390
Article Published Date
: Feb 01, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Miscarriage
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.
Dec 31, 2013
Add to My Research
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2014 ;2014:426740. Epub 2014 Aug 1. PMID:
25253919
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Pneumonia
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin D partially reversed the effect of lipopolysaccharide induced imbalances and protected patients with T2DM and DNU.
Aug 28, 2016
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Genet Mol Res. 2016 Aug 29 ;15(3). Epub 2016 Aug 29. PMID:
27706649
Article Published Date
: Aug 28, 2016
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Diabetes Mellitus: Type 2
,
Diabetic Nephropathy
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
50 Hz magnetic fields and lipopolysaccharides synergistically reduce cell viability in vitro.
Jan 10, 2016
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Pubmed Data
: Int J Radiat Biol. 2016 10 ;92(10):583-9. Epub 2016 Jul 19. PMID:
27430265
Article Published Date
: Jan 10, 2016
Study Type
: Human In Vitro
Additional Links
Diseases
:
DNA damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Radiation Induced Illness
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
[+]
Alpha-bisobolol inhibits lipopolysaccharide-induced inflammation.
Oct 01, 2011
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Pubmed Data
: Food Chem Toxicol. 2011 Oct ;49(10):2580-5. Epub 2011 Jul 13. PMID:
21771629
Article Published Date
: Oct 01, 2011
Study Type
: Human In Vitro
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Caffeic acid phenethyl ester could be effective for treating of periodontal diseases.
Nov 06, 2016
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Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Nov 7. Epub 2016 Aug 7. PMID:
27832944
Article Published Date
: Nov 06, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Periodontal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Citral inhibits LPS-induced inflammatory response via activating PPAR-γ which attenuates NF-κB activation.
Dec 10, 2015
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Pubmed Data
: Inflammation. 2015 Dec 11. Epub 2015 Dec 11. PMID:
26658749
Article Published Date
: Dec 10, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Citral
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Elderberry and elderflower extracts inhibit nitric oxide production in lipopolysaccharide-activated macrophages.
Mar 08, 2017
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Click here to read the entire abstract
Pubmed Data
: Int J Mol Sci. 2017 Mar 8 ;18(3). Epub 2017 Mar 8. PMID:
28282861
Article Published Date
: Mar 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Elderberry
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction.
Jan 10, 2017
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chest. 2017 11 ;152(5):954-962. Epub 2017 Jul 21. PMID:
28739448
Article Published Date
: Jan 10, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitamin C
Diseases
:
Endothelial Dysfunction
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.
Aug 31, 2012
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Pubmed Data
: J Pineal Res. 2012 Sep ;53(2):154-65. Epub 2012 Feb 21. PMID:
22348531
Article Published Date
: Aug 31, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Melatonin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Prostaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
Oleocanthal inhibits catabolic and inflammatory mediators in LPS-activated human primary osteoarthritis chondrocytes.
Dec 31, 2017
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;49(6):2414-2426. Epub 2018 Sep 27. PMID:
30261513
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Oleocanthal
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Plant polyphenols mitigate the pro-inflammatory and pro-oxidant adipocyte response to lipopolysaccharides.
Jan 01, 2017
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Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 05 ;119:303-312. Epub 2017 Feb 27. PMID:
28249816
Article Published Date
: Jan 01, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Resveratrol could be a prime candidate in ameliorating dysfunctioning adipose tissue induced by inflammatory stimulation.
Jan 01, 2016
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Click here to read the entire abstract
Pubmed Data
: PLoS One. 2016 ;11(7):e0159747. Epub 2016 Jul 20. PMID:
27438462
Article Published Date
: Jan 01, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
,
Stilbenes
Diseases
:
Inflammation
,
Insulin Resistance
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
Problem Substances
:
Insulin
[+]
Strawberry extracts efficiently counteract inflammatory stress induced by the endotoxin lipopolysaccharide.
Feb 15, 2018
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Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Feb 16. Epub 2018 Feb 16. PMID:
29458159
Article Published Date
: Feb 15, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Strawberry
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
T. cordifolia dry leaf extracts possess antioxidant and anti-inflammatory properties.
Jul 31, 2019
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Pubmed Data
: Phytomedicine. 2019 Aug ;61:152831. Epub 2019 Jan 10. PMID:
31035042
Article Published Date
: Jul 31, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Guduchi
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
These results showed for the first time a clear and a dose-dependent protective effect of strawberry extract on LPS-induced damage in HDF cell line.
Jan 20, 2017
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Article Publish Status
: This is a free article.
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Pubmed Data
: Molecules. 2017 Jan 21 ;22(1). Epub 2017 Jan 21. PMID:
28117711
Article Published Date
: Jan 20, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Strawberry
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
α-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.
Jan 01, 2014
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Click here to read the entire abstract
Pubmed Data
: Curr Pharm Biotechnol. 2014 ;15(2):173-81. PMID:
24894548
Article Published Date
: Jan 01, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
"Fucoidan enhances the survival and sustains the number of splenic dendritic cells in mouse endotoxemia."
Apr 01, 2011
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2011 Apr ;15(2):89-94. Epub 2011 Apr 30. PMID:
21660148
Article Published Date
: Apr 01, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
[+]
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevents lipopolysaccharide-induced depressive-like behaviours.
Dec 31, 2016
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Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2017 08 ;28(5):365-374. PMID:
28410266
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Anxiety
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment.
Oct 31, 2018
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Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Nov ;107:1523-1529. Epub 2018 Sep 5. PMID:
30257370
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gingerol
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A frankincense extract displayed anti-inflammatory, anti-oxidative, and hepatoprotective effects.
Dec 31, 2017
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2018 ;9:387. Epub 2018 Apr 20. PMID:
29731716
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
A hydro-alcoholic extract of nigella sativa reduced the LPS-induced sickness behaviors in rats.
Dec 31, 2015
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Pubmed Data
: Avicenna J Phytomed. 2016 Jan-Feb;6(1):104-16. PMID:
27247927
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Lipopolysaccharide-Induced Toxicity
Additional Keywords
:
Plant Extracts
[+]
A traditional Korean fermented soybean food exhibits anti-inflammatory activity which may have therapeutic value in allergic conditions such as asthma and atopic dermatitis.
Sep 01, 2008
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Pubmed Data
: J Med Food. 2008 Sep;11(3):539-43. PMID:
18800904
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Isoflavones
,
Soy
Diseases
:
Allergies
,
Asthma
,
Atopic Dermatitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Lipoxygenase Inhibitors
Additional Keywords
:
Plant Extracts
[+]
A water extract of Taraxacum mongolicum had a protective effect on lipopolysaccharide induced acute lung injury in mice.
Jun 19, 2015
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Pubmed Data
: J Ethnopharmacol. 2015 Jun 20 ;168:349-55. Epub 2015 Apr 8. PMID:
25861954
Article Published Date
: Jun 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
,
Lung Injury: Neutrophil-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
A. calamus prevented from memory deficits and stress through controlling oxidative stress and inflammation processes.
Dec 31, 2017
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Prev Med. 2018 ;9:85. Epub 2018 Oct 12. PMID:
30450168
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Acorus calamus
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.
Mar 14, 2017
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut Liver. 2017 Mar 15 ;11(2):243-252. PMID:
27965474
Article Published Date
: Mar 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Acai
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acteoside has a protective and therapeutic effect on LPS-induced immunological liver injury in mice.
Oct 31, 2009
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Pubmed Data
: Planta Med. 2009 Nov ;75(14):1463-9. Epub 2009 Jun 22. PMID:
19548187
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Acteoside has beneficial effects on lipopolysaccharide-induced inflammation in acute lung injury.
May 31, 2015
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Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2015 Jun 1 ;285(2):128-35. Epub 2015 Apr 19. PMID:
25902336
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Actinidia arguta extract attenuates inflammasome activation: Potential involvement in NLRP3 ubiquitination.
Feb 28, 2018
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Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2018 Mar 1 ;213:159-165. Epub 2017 Nov 21. PMID:
29174375
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Kiwifruit
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Plant Extracts
[+]
Aegle marmelos fruit extract attenuates Helicobacter pylori Lipopolysaccharide induced oxidative stress.
Oct 18, 2015
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 Oct 19 ;15:375. Epub 2015 Oct 19. PMID:
26482072
Article Published Date
: Oct 18, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Gastric Ulcer
,
Helicobacter Pylori Infection
,
Lipid Peroxidation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
AGE and RGE significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.
Sep 30, 2014
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Click here to read the entire abstract
Pubmed Data
: J Med Food. 2014 Oct ;17(10):1057-63. Epub 2014 Sep 19. PMID:
25238199
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Agrimony exhibits anti-inflammatory activity, substantiating its traditional uses for inflammation and allergic diseases.
Jan 01, 2010
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Click here to read the entire abstract
Pubmed Data
: Immunol Invest. 2010 Jan;39(2):159-70. PMID:
20136621
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Agrimony
Diseases
:
Allergies
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Science Confirms Tradition
[+]
Allicin attenuates lipopolysaccharide‑induced acute lung injury.
Mar 06, 2018
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Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Mar 7. Epub 2018 Mar 7. PMID:
29512749
Article Published Date
: Mar 06, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alliin ameliorates DSS-induced ulcerative colitis and inhibits the inflammatory responses in LPS-stimulated RAW264.7 cells.
Mar 29, 2017
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Pubmed Data
: Mol Nutr Food Res. 2017 Mar 30. Epub 2017 Mar 30. PMID:
28371322
Article Published Date
: Mar 29, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Allyl isothiocyanate ameliorates dextran sodium sulfate-induced colitis.
Jul 11, 2018
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Article Publish Status
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Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2018 Jul 12 ;19(7). Epub 2018 Jul 12. PMID:
30002285
Article Published Date
: Jul 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Isothiocyanates
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Alpha-linolenic acid protects against lipopolysaccharide-induced acute lung injury through anti-inflammatory and anti-oxidative pathways.
Feb 17, 2020
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Article Publish Status
: This is a free article.
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Pubmed Data
: Microb Pathog. 2020 Feb 18 ;142:104077. Epub 2020 Feb 18. PMID:
32084579
Article Published Date
: Feb 17, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha Linolenic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Amygdalin reduces lipopolysaccharide-induced chronic liver injury.
Nov 30, 2019
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):2688-2697. PMID:
31257932
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin (laetrile)
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties.
May 31, 2007
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Pubmed Data
: J Pharm Pharmacol. 2007 Jun ;59(6):891-7. PMID:
17637182
Article Published Date
: May 31, 2007
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Celery
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
An extract of Stevia rebaudiana leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury.
Oct 31, 2017
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Pubmed Data
: Biomed Pharmacother. 2017 Nov ;95:1040-1050. Epub 2017 Sep 13. PMID:
28922721
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Stevia
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Antarctic krill oil diet protects against lipopolysaccharide-induced oxidative stress, neuroinflammation and cognitive impairment.
Nov 27, 2017
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Article Publish Status
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Pubmed Data
: Int J Mol Sci. 2017 Nov 28 ;18(12). Epub 2017 Nov 28. PMID:
29182579
Article Published Date
: Nov 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Neuroprotective Agents
[+]
Anthocyanin-rich fractions from red raspberries attenuate inflammation both in vitro and in vivo.
Dec 31, 2013
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Article Publish Status
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Pubmed Data
: Sci Rep. 2014 ;4:6234. Epub 2014 Aug 29. PMID:
25167935
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Raspberry
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory and antioxidant properties of black mulberry in a Model of LPS-induced sepsis.
Dec 31, 2017
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Article Publish Status
: This is a free article.
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Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:5048031. Epub 2018 Nov 7. PMID:
30524657
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Mulberry
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol.
Sep 04, 2015
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Pubmed Data
: Eur J Pharmacol. 2015 Sep 5 ;762:333-43. Epub 2015 Jun 6. PMID:
26054809
Article Published Date
: Sep 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.
Apr 14, 2016
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Pubmed Data
: Biochem Pharmacol. 2016 Apr 15 ;106:82-93. Epub 2016 Mar 3. PMID:
26947453
Article Published Date
: Apr 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Bone Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Antibiotic-induced depletion of murine microbiota induces mild inflammation.
Sep 30, 2015
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Pubmed Data
: Microb Ecol. 2015 Oct ;70(3):835-48. Epub 2015 Apr 21. PMID:
25896428
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Antibiotic Toxicity
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Additional Keywords
:
Microbiota
Problem Substances
:
Antibiotics
[+]
Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.
Dec 31, 2016
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Article Publish Status
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Pubmed Data
: Drug Des Devel Ther. 2017 ;11:103-121. Epub 2016 Dec 28. PMID:
28096658
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curry Leaves
Diseases
:
Colon Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Apoptotic
[+]
Antidepressant-like effect and mechanism of action of honokiol in lipopolysaccharide depression model.
May 27, 2019
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Pubmed Data
: Molecules. 2019 May 28 ;24(11). Epub 2019 May 28. PMID:
31141940
Article Published Date
: May 27, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interferon Gamma Reducer
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antidepressant-like effects of β-caryophyllene on restraint plus stress-induced depression.
Feb 16, 2020
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Pubmed Data
: Behav Brain Res. 2020 Feb 17 ;380:112439. Epub 2019 Dec 17. PMID:
31862467
Article Published Date
: Feb 16, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Beta-Caryophyllene
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
Additional Keywords
:
Endocannabinoid System
[+]
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Apr 30, 2017
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Pubmed Data
: Int Immunopharmacol. 2017 May ;46:124-132. Epub 2017 Mar 7. PMID:
28282576
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Paeonol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Failure: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Anti‑inflammatory effects of Panax notoginseng saponins ameliorate acute lung injury induced by oleic acid and lipopolysaccharide.
Aug 31, 2014
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Pubmed Data
: Mol Med Rep. 2014 Sep ;10(3):1400-8. Epub 2014 Jun 16. PMID:
24938646
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Panax Notoginseng
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Arctigenin has anti-inflammatory and antioxidative effects on LPS-induced acute lung injury.
Jul 31, 2015
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Pubmed Data
: Inflammation. 2015 Aug ;38(4):1406-14. PMID:
25616905
Article Published Date
: Jul 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Ascorbic acid attenuated the inflammatory response and fibrosis in the lungs of rats treated with lipopolysaccharide.
Dec 31, 2018
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Article Publish Status
: This is a free article.
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Pubmed Data
: SAGE Open Med. 2019 ;7:2050312119828260. Epub 2019 Feb 4. PMID:
30783524
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Fibrosis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
[+]
Ascorbic acid attenuates lipopolysaccharide-induced acute lung injury.
May 31, 2011
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Pubmed Data
: Crit Care Med. 2011 Jun ;39(6):1454-60. PMID:
21358394
Article Published Date
: May 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Ascorbic acid modulates in vitro the function of macrophages from mice with endotoxic shock.
Dec 31, 1999
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Pubmed Data
: Immunopharmacology. 2000 Jan ;46(1):89-101. PMID:
10665783
Article Published Date
: Dec 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Shock: Endotoxic
Pharmacological Actions
:
Antioxidants
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Asiatic acid inhibits lipopolysaccharide-induced acute lung injury in mice.
Sep 30, 2016
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Click here to read the entire abstract
Pubmed Data
: Inflammation. 2016 Oct ;39(5):1642-8. PMID:
27395046
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astaxanthin ameliorates lipopolysaccharide-induced neuroinflammation, oxidative stress and memory dysfunction.
Feb 17, 2019
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Article Publish Status
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Pubmed Data
: Mar Drugs. 2019 Feb 18 ;17(2). Epub 2019 Feb 18. PMID:
30781690
Article Published Date
: Feb 17, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Astaxanthin ameliorates the behavioural deficits of prenatal maternal LPS-exposure.
Dec 31, 2015
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Pubmed Data
: BMC Neurosci. 2016 ;17(1):11. Epub 2016 Feb 8. PMID:
26856812
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Prenatal Chemical Exposures
Pharmacological Actions
:
Antioxidants
[+]
Astaxanthin ameliorates the lipopolysaccharides-induced subfertility.
Jun 30, 2019
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Article Publish Status
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Pubmed Data
: Dose Response. 2019 Jul-Sep;17(3):1559325819878537. Epub 2019 Sep 25. PMID:
31598118
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Infertility: Male
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Fertility Agents: Male
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Astaxanthin prevents against lipopolysaccharide-induced acute lung injury and sepsis.
Dec 31, 2018
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Pubmed Data
: Am J Transl Res. 2019 ;11(3):1884-1894. Epub 2019 Mar 15. PMID:
30972212
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Astragaloside IV alleviates lipopolysaccharide-induced acute kidney injury.
Mar 21, 2017
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Pubmed Data
: Med Sci Monit. 2017 Mar 22 ;23:1413-1420. Epub 2017 Mar 22. PMID:
28328867
Article Published Date
: Mar 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Inflammation
,
Kidney Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.
Nov 30, 2016
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Pubmed Data
: Int Immunopharmacol. 2016 Dec ;41:47-55. Epub 2016 Nov 2. PMID:
27816726
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Aspirin-Induced Toxicity
,
Gastric Ulcer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Aspirin
[+]
Astragaloside IV suppresses inflammatory mediator production in synoviocytes and collagen‑induced arthritic rats.
Mar 31, 2016
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Pubmed Data
: Mol Med Rep. 2016 Apr ;13(4):3289-96. Epub 2016 Feb 22. PMID:
26936538
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Arthritis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Attenuating effect of Ginsenoside Rb1 on LPS-induced lung injury in rats.
Dec 31, 2013
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Article Publish Status
: This is a free article.
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Pubmed Data
: J Inflamm (Lond). 2014 ;11(1):40. Epub 2014 Dec 5. PMID:
25530718
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Barley sprouts have a protective effect against alcohol-induced liver injury.
Jul 20, 2016
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Article Publish Status
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Pubmed Data
: Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID:
27455313
Article Published Date
: Jul 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Barley
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Bay leaf contains compounds which inhibit LPS-activated nitric oxide production and which induce heat shock protein.
Apr 21, 2000
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Pubmed Data
: Life Sci. 2000 Apr 21;66(22):2151-7. PMID:
10834299
Article Published Date
: Apr 21, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Bay leaf
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Enzyme Inhibitors
,
Heat Shock Protein Inducer
,
Nitric Oxide Inhibitor
[+]
Bee venom soluble phospholipase A2 exerts neuroprotective effects in a lipopolysaccharide-induced mouse model of Alzheimer's disease.
Dec 31, 2018
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Article Publish Status
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Pubmed Data
: Front Aging Neurosci. 2019 ;11:287. Epub 2019 Nov 1. PMID:
31736738
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Alzheimer's Disease
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Beneficial effects of tea water extracts on the body weight and gut microbiota in C57BL/6J mice fed with a high-fat diet.
May 06, 2019
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Pubmed Data
: Food Funct. 2019 May 7. Epub 2019 May 7. PMID:
31062778
Article Published Date
: May 06, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Green Tea
Diseases
:
High Fat Diet
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Berberine alleviates endothelial glycocalyx degradation and promotes glycocalyx restoration in LPS-induced ARDS.
Oct 07, 2018
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Pubmed Data
: Int Immunopharmacol. 2018 Oct 8 ;65:96-107. Epub 2018 Oct 8. PMID:
30308440
Article Published Date
: Oct 07, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Acute Respiratory Distress Syndrome
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine can be a potential therapeutic agent for osteoclast-related bone diseases.
Mar 03, 2019
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Pubmed Data
: Am J Chin Med. 2019 Mar 4:1-17. Epub 2019 Mar 4. PMID:
30827151
Article Published Date
: Mar 03, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Bone Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Osteoprotective
[+]
Berberine hydrochloride can provide mice robust protection from LPS-induced mastitis.
Dec 31, 2017
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Article Publish Status
: This is a free article.
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Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:5164314. Epub 2018 Apr 15. PMID:
29849710
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Mastitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes.
Dec 31, 2019
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Article Publish Status
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Pubmed Data
: PLoS One. 2020 ;15(5):e0232630. Epub 2020 May 1. PMID:
32357187
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Beta glucan inhibits experimental periodontal disease possibly through steering the T helper Th1/Th2 balance towards Th1 and T regulatory responses.
Apr 01, 2005
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Pubmed Data
: J Clin Periodontol. 2005 Apr;32(4):347-52. PMID:
15811050
Article Published Date
: Apr 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Beta-glucan
Diseases
:
Immune Dysregulation: TH1/TH2 imbalance
,
Lipopolysaccharide-Induced Toxicity
,
Periodontal Diseases
Pharmacological Actions
:
Immunomodulatory
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Biochanin A exerts protective effects on lipopolysaccharide-induced Parkinson's disease.
Jan 09, 2016
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Pubmed Data
: Neurotox Res. 2016 10 ;30(3):486-98. Epub 2016 Jul 14. PMID:
27417698
Article Published Date
: Jan 09, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Biochanin A protect against lipopolysaccharide-induced acute lung injury.
Dec 31, 2019
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Article Publish Status
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Pubmed Data
: Microb Pathog. 2020 Jan ;138:103846. Epub 2019 Nov 4. PMID:
31698051
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury.
Aug 31, 2016
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Pubmed Data
: Int Immunopharmacol. 2016 Sep ;38:324-31. Epub 2016 Jun 23. PMID:
27344638
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Black Adzuki bean attenuates high-fat diet-induced colon inflammation.
Mar 31, 2017
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Pubmed Data
: J Med Food. 2017 Apr ;20(4):367-375. PMID:
28406732
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Aduki bean
Diseases
:
Colitis
,
High Fat Diet
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Brazilian propolis contains some natural products that can decrease thrombotic tendencies in mice.
Aug 31, 2016
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Pubmed Data
: J Intercult Ethnopharmacol. 2016 Sep-Dec;5(4):439-443. Epub 2016 Aug 17. PMID:
27757277
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Brazillian
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-thrombotic
[+]
Buckwheat sprouts have an anti-inflammatory effect in lipopolysaccharide-activated human colon cancer cells and mice.
Dec 01, 2008
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Pubmed Data
: Biosci Biotechnol Biochem. 2008 Dec;72(12):3148-57. Epub 2008 Dec 7. PMID:
19060399
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
,
Sprouts
Diseases
:
Colon Cancer
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Butyrate and dietary soluble fiber improves neuroinflammation associated with aging.
Dec 31, 2017
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Pubmed Data
: Front Immunol. 2018 ;9:1832. Epub 2018 Aug 14. PMID:
30154787
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Butyrate
,
Fiber
Diseases
:
Aging
,
Brain Inflammation
,
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Epigenetic Modification
[+]
By promoting fertility and eliminating oxidative stress and inflammation, Punicalagin may be a useful nutrient for the treatment of infertility.
Jan 11, 2016
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Article Publish Status
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Pubmed Data
: Asian J Androl. 2016 Jan 12. Epub 2016 Jan 12. PMID:
26763544
Article Published Date
: Jan 11, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Infertility: Male
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Fertility Agents
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
C. obtusa essential oil may constitute a novel source of anti-inflammatory treatments.
Jun 30, 2013
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Pubmed Data
: Mol Med Rep. 2013 Jul ;8(1):255-9. Epub 2013 May 8. PMID:
23652412
Article Published Date
: Jun 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Japanese cypress
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Oils
[+]
Caffeine may abrogate lipopolysaccharide-induced oxidative stress and neuroinflammation.
Nov 07, 2019
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Article Publish Status
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Pubmed Data
: Biomolecules. 2019 Nov 8 ;9(11). Epub 2019 Nov 8. PMID:
31717470
Article Published Date
: Nov 07, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Caffeine
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Cannabidiol has a neuroprotective effect in endotoxin-induced uveitis.
Jan 01, 2008
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Pubmed Data
: Mol Vis. 2008;14:2190-203. Epub 2008 Dec 3. PMID:
19052649
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Brain: Microglial Activation
,
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Uveitis
Pharmacological Actions
:
Enzyme Inhibitors
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.
Aug 14, 2000
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Pubmed Data
: Proc Natl Acad Sci U S A. 2000 Aug 15 ;97(17):9561-6. PMID:
10920191
Article Published Date
: Aug 14, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
,
Cannabis
Diseases
:
Arthritis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunosuppressive Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol might become a useful therapeutic tool for the attenuation and treatment of inflammatory lung diseases.
Jan 31, 2015
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Pubmed Data
: Immunopharmacol Immunotoxicol. 2015 Feb ;37(1):35-41. Epub 2014 Oct 30. PMID:
25356537
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Interstitial Lung Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabinoids may have therapeutic value in neurodegenerative conditions by preventing and/or reducing neuroinflammation.
Feb 23, 2007
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Pubmed Data
: Neuroscience. 2007 Feb 23 ;144(4):1516-22. Epub 2006 Dec 18. PMID:
17178196
Article Published Date
: Feb 23, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cannabinoids
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome.
Jun 30, 2019
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Article Publish Status
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Pubmed Data
: Acta Pharm Sin B. 2019 Jul ;9(4):734-744. Epub 2019 Feb 14. PMID:
31384534
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cardamonin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Septic Shock
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Carnosic acid protects against lipopolysaccharide-induced acute lung injury in mice.
Oct 31, 2019
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Pubmed Data
: Exp Ther Med. 2019 Nov ;18(5):3707-3714. Epub 2019 Sep 23. PMID:
31611929
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Carvacrol has significant potential as an inhibitor of memory degeneration in neurodegenerative diseases.
Dec 31, 2019
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Pubmed Data
: Korean J Physiol Pharmacol. 2020 Jan ;24(1):27-37. Epub 2020 Dec 20. PMID:
31908572
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
,
Neurodegenerative Diseases
Pharmacological Actions
:
Neuroprotective Agents
[+]
Carvacrol prevents the proconvulsant effect of LPS possibly through the inhibition of the COX-2 increased activity.
Jan 11, 2018
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Pubmed Data
: Metab Brain Dis. 2018 12 ;33(6):2045-2050. Epub 2018 Sep 18. PMID:
30229386
Article Published Date
: Jan 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Seizures
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Celastrol inhibits microglial pyroptosis and attenuates inflammatory reaction in acute spinal cord injury rats.
Dec 31, 2018
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Pubmed Data
: Int Immunopharmacol. 2019 Jan ;66:215-223. Epub 2018 Nov 22. PMID:
30472522
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Celastrol
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Centella asiantica has a protective effect against acute liver injury in mice.
Feb 17, 2010
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Pubmed Data
: Phytomedicine. 2010 Feb 17. Epub 2010 Feb 17. PMID:
20171071
Article Published Date
: Feb 17, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Centella asiatica
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Chilean white strawberry aqueous extract favours the normalization of oxidative and inflammatory responses after a liver injury induced by LPS.
Dec 31, 2014
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Article Publish Status
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Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:320136. Epub 2015 Sep 17. PMID:
26457108
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Strawberry
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chronic consumption of γ-oryzanol can revert the LPS-induced cognitive and memory impairments by promoting hippocampal antioxidant and anti-inflammatory molecular responses.
Mar 29, 2019
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Pubmed Data
: Nutrients. 2019 Mar 29 ;11(4). Epub 2019 Mar 29. PMID:
30934852
Article Published Date
: Mar 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gamma-Oryzanol
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation.
Aug 01, 2007
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Pubmed Data
: J Neurochem. 2007 Aug;102(3):761-72. Epub 2007 May 4. PMID:
17488274
Article Published Date
: Aug 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Lithium
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Chrysanthemum indicum has a protective effect on acute lung injury induced by lipopolysaccharide.
Dec 31, 2013
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Article Publish Status
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Pubmed Data
: Mediators Inflamm. 2014 ;2014:246407. Epub 2014 Aug 25. PMID:
25214712
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Cigarette smoke exposure combined with lipopolysaccharides induced pulmonary fibrosis in mice.
Jul 31, 2019
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Pubmed Data
: Respir Physiol Neurobiol. 2019 Aug ;266:9-17. Epub 2019 Apr 22. PMID:
31022471
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Pulmonary Fibrosis
Problem Substances
:
Electronic Cigarettes
[+]
Clorpyrifos significantly altered the gut microbiota composition.
May 31, 2016
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Pubmed Data
: Chemosphere. 2016 Jun ;153:287-93. Epub 2016 Mar 26. PMID:
27018521
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
,
Pesticide Toxicity
Additional Keywords
:
Microbiota
Problem Substances
:
Chlorpyrifos
,
Pesticides
[+]
Constituents of Moringa oleifera seeds regulate expression of Th17-relevant cytokines and ameliorate TPA-induced psoriasis-like skin lesions.
Dec 09, 2018
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Article Publish Status
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Pubmed Data
: Molecules. 2018 Dec 10 ;23(12). Epub 2018 Dec 10. PMID:
30544700
Article Published Date
: Dec 09, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-12 downregulation
,
Interleukin-23 Downregulation
Additional Keywords
:
Plant Extracts
[+]
CoQ10 supplementation reduces broiler chickens' susceptibility to ascites through improving mitochondrial function.
Sep 01, 2003
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Pubmed Data
: Angiology. 2003 Sep-Oct;54(5):531-9. PMID:
16359119
Article Published Date
: Sep 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Ascites
,
Lipopolysaccharide-Induced Toxicity
[+]
Cordyceps suppresses the expression of diabetes regulating genes by inhibiting lipopolysaccharide-induced inflammation in macrophages.
Jun 01, 2009
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Pubmed Data
: Immune Netw. 2009 Jun;9(3):98-105. Epub 2009 Jun 30. PMID:
20107539
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps sinensis
Diseases
:
Diabetes Mellitus: Type 2
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Corn silk extract ameliorated lipopolysaccharide-induced inflammation in mice.
Jan 31, 2017
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Pubmed Data
: J Agric Food Chem. 2017 Feb 1 ;65(4):759-768. Epub 2017 Jan 17. PMID:
28064493
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Corn Silk
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Crocetin may be used as a novel therapy for preventing fulminant hepatic failure.
Oct 31, 2019
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Article Publish Status
: This is a free article.
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Pubmed Data
: Exp Ther Med. 2019 Nov ;18(5):3775-3782. Epub 2019 Sep 19. PMID:
31616509
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Crocetin
Diseases
:
Fulminant Hepatic Failure
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome.
Jan 09, 2020
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Pubmed Data
: Inflamm Res. 2020 Jan 10. Epub 2020 Jan 10. PMID:
31925528
Article Published Date
: Jan 09, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Crocin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Respiratory Distress Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Crocus sativus, Serenoa repens and Pinus massoniana extracts modulate inflammatory response in isolated rat prostate challenged with LPS.
Jun 30, 2017
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Pubmed Data
: J Biol Regul Homeost Agents. 2017 Jul-Sep,;31(3):531-541. PMID:
28889734
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Pine Bark Extract
,
Saffron
,
Saw Palmetto
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Curcumin administration could be used as supplementary therapeutic intervention at early stage of endotoxemia.
Mar 12, 2017
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Pubmed Data
: Inflammopharmacology. 2017 Mar 13. Epub 2017 Mar 13. PMID:
28289922
Article Published Date
: Mar 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin alleviated lung edema in lipopolysaccharide induced acute lung injury by inhibiting inflammation.
Feb 25, 2018
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Article Publish Status
: This is a free article.
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Pubmed Data
: Med Sci Monit. 2018 Feb 26 ;24:1178-1184. Epub 2018 Feb 26. PMID:
29480285
Article Published Date
: Feb 25, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Curcumin ameliorates endotoxin-induced experimental hepatoxicity in rodents.
Aug 01, 2006
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Pubmed Data
: Clin Exp Immunol. 2006 Aug;145(2):313-21. PMID:
16879252
Article Published Date
: Aug 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin and selenium can hinder the progression and severity of liver injury during acute inflammatory episodes.
Oct 24, 2019
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Pubmed Data
: Biol Trace Elem Res. 2019 Oct 25. Epub 2019 Oct 25. PMID:
31654258
Article Published Date
: Oct 24, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Selenium
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Diclofenac
[+]
Curcumin attenuates lipopolysaccharide-induced renal inflammation.
Jan 01, 2011
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Pubmed Data
: Biol Pharm Bull. 2011;34(2):226-32. PMID:
21415532
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Inflammatory Kidney Diseases
,
Kidney Infection
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Renoprotective
[+]
Curcumin compares favorably with bisdemethoxycurcumin in a gastric ulcer model system.
Apr 01, 2009
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Pubmed Data
: Phytomedicine. 2009 Apr;16(4):342-51. Epub 2009 Feb 1. PMID:
19188055
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bisdemethoxycurcumin
,
Curcumin
Diseases
:
Gastric Ulcer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Ulcer Agents
,
Proton Pump Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin has a neuroprotective effect on focal cerebral ischemic rats by preventing blood-brain barrier damage.
Jan 01, 2010
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Pubmed Data
: Chemotherapy. 2010;56(1):60-5. Epub 2010 Mar 19. PMID:
17303117
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Blood-Brain-Barrier Disorders
,
Brain Ischemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin inhibits liver injury in a mouse model of endotoxemic shock.
Feb 01, 2010
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Pubmed Data
: Biotechnol Lett. 2010 Feb;32(2):209-14. Epub 2009 Oct 25. PMID:
19856147
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits.
Sep 28, 2008
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Pubmed Data
: Eur J Pharmacol. 2008 Sep 28;593(1-3):105-11. Epub 2008 Jul 15. PMID:
18664365
Article Published Date
: Sep 28, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Fever
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-pyretic
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin modulates the immune response associated with LPS-induced periodontal disease in rats, indicating its potential therapeutic value.
Jan 17, 2011
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Pubmed Data
: Innate Immun. 2011 Jan 17. Epub 2011 Jan 17. PMID:
21242275
Article Published Date
: Jan 17, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Periodontal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Curcumin protects against experimental liver injury in mice.
Aug 01, 2003
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Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2003 Aug;28(8):756-8, 793. PMID:
15015361
Article Published Date
: Aug 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin protects pre-oligodendrocytes from activated microglia, indicating it may play a role in protecting against preterm periventricular leukomalacia (PVL).
Jun 21, 2010
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Pubmed Data
: Brain Res. 2010 Jun 21;1339:60-9. Epub 2010 Apr 24. PMID:
20403340
Article Published Date
: Jun 21, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Preterm Periventricular Leukomalacia (PVL)
Pharmacological Actions
:
Apoptotic
,
Enzyme Inhibitors
,
Neuroprotective Agents
[+]
Curcumin reduces nitric oxide formation and associated inflammation in the rat mammary gland.
Jan 01, 2009
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Pubmed Data
: J Exp Biol. 2009 Jan;212(Pt 2):163-8. PMID:
11020339
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antineoplastic Agents
,
Antioxidants
,
Nitric Oxide Inhibitor
[+]
Curcumin treatment attenuates lipopolysaccharide induced liver injury.
Jul 05, 2016
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Pubmed Data
: Biomed Pharmacother. 2016 Jul 6 ;83:302-313. Epub 2016 Jul 6. PMID:
27393927
Article Published Date
: Jul 05, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Dandelion protects against lipopolysaccharide-induced acute lung injury in mice.
Jul 20, 2010
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Pubmed Data
: J Ethnopharmacol. 2010 Jul 20;130(2):392-7. Epub 2010 May 25. PMID:
20510343
Article Published Date
: Jul 20, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Diallyl sulfide protects against lipopolysaccharide/d-galactosamine-induced acute liver injury.
Jul 30, 2018
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Pubmed Data
: Food Chem Toxicol. 2018 Jul 31 ;120:500-509. Epub 2018 Jul 31. PMID:
30075314
Article Published Date
: Jul 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Diallyl sulfide
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary addition of flaxseed oil enhances intestinal integrity and barrier function.
Apr 30, 2018
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Pubmed Data
: Mol Nutr Food Res. 2018 May ;62(9):e1700814. Epub 2018 Apr 14. PMID:
29510469
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed Oil
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastroprotective
[+]
Dietary arginine supplementation alleviates intestinal mucosal disruption induced by Escherichia coli lipopolysaccharide in weaned pigs.
Sep 01, 2008
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Pubmed Data
: Br J Nutr. 2008 Sep;100(3):552-60. Epub 2008 Feb 14. PMID:
18275628
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
Diseases
:
Escherichia coli Infections
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary histidine ameliorates mouse colitis through the inhibition of proinflammatory cytokine production from macrophages.
Feb 01, 2009
Add to My Research
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Pubmed Data
: Gastroenterology. 2009 Feb;136(2):564-74.e2. Epub 2008 Oct 7. PMID:
19027739
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Histidine
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary intake of ascorbic acid attenuates lipopolysaccharide-induced sepsis and septic inflammation.
Dec 31, 2017
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Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 2018 ;64(6):404-411. PMID:
30606963
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
dietary L. casei alleviates LPS-induced liver injury via reducing pro-inflammatory cytokines and increasing anti-oxidative capacity.
Nov 25, 2017
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Pubmed Data
: Int J Mol Sci. 2017 Nov 26 ;18(12). Epub 2017 Nov 26. PMID:
29186870
Article Published Date
: Nov 25, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus casei
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress caused by lipopolysaccharide.
Dec 10, 2019
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Pubmed Data
: J Anim Sci. 2019 Dec 11. Epub 2019 Dec 11. PMID:
31822918
Article Published Date
: Dec 10, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Pterostilbene
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Gastroprotective
[+]
Diosgenin attenuates lipopolysaccharide-induced Parkinson's disease.
Dec 31, 2017
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Pubmed Data
: J Alzheimers Dis. 2018 ;64(3):943-955. PMID:
29966203
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Diosmetin inhibits osteoclast formation and differentiation and prevents LPS-induced osteolysis in mice.
Jul 31, 2019
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Pubmed Data
: J Cell Physiol. 2019 Aug ;234(8):12701-12713. Epub 2018 Dec 4. PMID:
30515812
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Diosmetin
Diseases
:
Bone Diseases: Over-Active Osteoclasts
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Osteoprotective
[+]
Diosmin is a promising molecule for the treatment of inflammation and pain.
Feb 20, 2020
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Pubmed Data
: J Nat Prod. 2020 Feb 21. Epub 2020 Feb 21. PMID:
32083866
Article Published Date
: Feb 20, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Echinacea reduces Candida albicans associated mortality in mice.
Jan 01, 2006
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Pubmed Data
: J Cardiovasc Pharmacol. 2006;47 Suppl 2:S177-86; discussion S206-9. PMID:
15949903
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Echinacea
Diseases
:
Candida Infection
,
Immune Disorders: Low Immune Function
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Immunostimulatory
Additional Keywords
:
Plant Extracts
[+]
EGCG has a beneficial effect on impaired adult neurogenesis caused by lipopolysaccharide induced neuro-inflammation.
Dec 31, 2015
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Article Publish Status
: This is a free article.
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Pubmed Data
: Korean J Physiol Pharmacol. 2016 Jan ;20(1):41-51. Epub 2015 Dec 31. PMID:
26807022
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ellagic acid protects lipopolysaccharide/D-galactosamine-induced acute hepatic injury.
Sep 30, 2014
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Pubmed Data
: Int Immunopharmacol. 2014 Oct ;22(2):341-5. Epub 2014 Jul 16. PMID:
25038320
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 inducer
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Embelia ribes ameliorates lipopolysaccharide-induced acute respiratory distress syndrome.
Jun 19, 2015
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Pubmed Data
: J Ethnopharmacol. 2015 Jun 20 ;168:356-63. Epub 2015 Mar 27. PMID:
25818695
Article Published Date
: Jun 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
False Black Pepper
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Respiratory Distress Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
[+]
Emodin alleviated LPS-induced pulmonary inflammation in rat lung tissues.
Mar 31, 2020
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Pubmed Data
: Inflamm Res. 2020 Apr ;69(4):365-373. Epub 2020 Mar 4. PMID:
32130427
Article Published Date
: Mar 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Emodin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Emodin showed excellent hepatoprotective effects against lipopolysaccharide-induced acute liver injury.
Dec 31, 2017
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Article Publish Status
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Pubmed Data
: Front Pharmacol. 2018 ;9:962. Epub 2018 Aug 22. PMID:
30186181
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Emodin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Eriodictyol alleviates lipopolysaccharide-triggered oxidative stress and synaptic dysfunctions.
Aug 31, 2019
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Pubmed Data
: J Cell Biochem. 2019 Sep ;120(9):14756-14770. Epub 2019 Apr 23. PMID:
31016762
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Eriodictyol
Diseases
:
Brain: Oxidative Stress
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Eriodictyol attenuates lipopolysaccharide-induced acute lung injury through its antioxidative and anti-inflammatory activity.
Nov 30, 2015
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Article Publish Status
: This is a free article.
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Pubmed Data
: Exp Ther Med. 2015 Dec ;10(6):2259-2266. Epub 2015 Oct 23. PMID:
26668626
Article Published Date
: Nov 30, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Eriodictyol
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Nrf2 activation
[+]
Eriodictyol attenuates LPS-induced neuroinflammation, amyloidogenesis, and cognitive impairments.
Oct 02, 2018
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Pubmed Data
: J Agric Food Chem. 2018 Oct 3 ;66(39):10205-10214. Epub 2018 Sep 21. PMID:
30208700
Article Published Date
: Oct 02, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Eriodictyol
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Eriodictyol exhibited an immunomodulatory effect that could be ascribed in part to a cytoprotective effect related to its anti-oxidant activity.
Dec 31, 2015
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Pubmed Data
: Cell Stress Chaperones. 2016 09 ;21(5):773-81. Epub 2016 Jun 1. PMID:
27250501
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Eriodictyol
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Immunomodulatory
[+]
Essential oils extracted from Chamaecyparis obtusa may be considered an effective therapeutic agent for the treatment of inflammatory diseases.
Mar 31, 2016
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Pubmed Data
: Mol Med Rep. 2016 Apr ;13(4):3335-41. Epub 2016 Feb 18. PMID:
26936418
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Japanese cypress
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Essential Oils
[+]
Eucalyptus globulus suppressed the monosodium urate-induced peritonitis.
Dec 31, 2017
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Pubmed Data
: Am J Chin Med. 2018 ;46(2):423-433. Epub 2018 Feb 12. PMID:
29433388
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Eucalyptus
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Peritonitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Fecal microbiota transplantation regulates the cholinergic anti-inflammatory pathway in cerebral cortex of septic rats.
Aug 31, 2019
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Article Publish Status
: This is a free article.
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Pubmed Data
: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2019 Sep ;31(9):1102-1107. PMID:
31657333
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Therapeutic Actions
:
Microbiota Transfer Therapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Fecal transplantation can alleviate lipopolysaccharide-induced acute lung injury.
May 27, 2019
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Pubmed Data
: Zhonghua Yi Xue Za Zhi. 2019 May 28 ;99(20):1582-1587. PMID:
31154727
Article Published Date
: May 27, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Therapeutic Actions
:
Microbiota Transfer Therapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Fermented barley extract effectively inhibited the propagation of inflammation by suppressing oxidative stress.
Dec 31, 2010
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Article Publish Status
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Pubmed Data
: Biosci Biotechnol Biochem. 2011 ;75(10):1971-6. Epub 2011 Oct 7. PMID:
21979071
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Barley
,
Fermented Foods and Beverages
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Ferulic acid alleviated LPS-induced acute respiratory distress syndrome through its anti-inflammatory and anti-oxidant activities.
Dec 31, 2017
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Pubmed Data
: Int J Immunopathol Pharmacol. 2018 Jan-Dec;32:394632017750518. PMID:
29350567
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ferulic acid
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Respiratory Distress Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
[+]
Ferulic acid protects lipopolysaccharide-induced acute kidney injury.
Mar 31, 2018
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Pubmed Data
: Biomed Pharmacother. 2018 Apr ;100:304-315. Epub 2018 Feb 16. PMID:
29448207
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ferulic acid
Diseases
:
Kidney Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
[+]
Fisetin administration improves LPS-induced acute otitis media.
Jun 30, 2018
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Pubmed Data
: Int J Mol Med. 2018 Jul ;42(1):237-247. Epub 2018 Mar 22. PMID:
29568876
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Otitis media
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Fisetin alleviated kidney inflammation and apoptosis to protect against lipopolysaccharide-induced septic acute kidney injury.
Jan 31, 2020
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Article Publish Status
: This is a free article.
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Pubmed Data
: Biomed Pharmacother. 2020 Feb ;122:109772. Epub 2019 Dec 30. PMID:
31918290
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Kidney Damage
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Fisetin improved the hippocampal-dependent synaptic and memory functions in LPS-treated adult mice.
Jun 13, 2019
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Article Publish Status
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Pubmed Data
: J Clin Med. 2019 Jun 14 ;8(6). Epub 2019 Jun 14. PMID:
31207963
Article Published Date
: Jun 13, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Brain: Oxidative Stress
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Fisetin may be an effective therapeutic agent for LPS-induced depressive-like behaviours.
May 20, 2016
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Pubmed Data
: Metab Brain Dis. 2016 May 21. Epub 2016 May 21. PMID:
27209403
Article Published Date
: May 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Flos Lonicera ameliorates obesity and associated endotoxemia.
Dec 31, 2013
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Article Publish Status
: This is a free article.
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Pubmed Data
: PLoS One. 2014 ;9(1):e86117. Epub 2014 Jan 24. PMID:
24475077
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Honeysuckle
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
,
Obesity
Pharmacological Actions
:
Gastrointestinal Agents
Additional Keywords
:
Anti-Obesity Agents
,
Plant Extracts
[+]
Formononetin has a protective effect on lipopolysaccharide-induced acute lung injury in mice.
Nov 30, 2013
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Pubmed Data
: Inflammation. 2013 Dec ;36(6):1560-6. PMID:
23907652
Article Published Date
: Nov 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Formononetin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Fucoidan inhibits LPS-induced inflammation in vitro and during the acute response in vivo.
Jan 31, 2017
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Pubmed Data
: Int Immunopharmacol. 2017 Feb ;43:91-98. Epub 2016 Dec 14. PMID:
27987467
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Fucoxanthin prevents lipopolysaccharide-induced depressive-like behavior in mice.
Dec 14, 2018
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Pubmed Data
: Metab Brain Dis. 2018 Dec 15. Epub 2018 Dec 15. PMID:
30554399
Article Published Date
: Dec 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fucoxanthin
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Galangin has a role in protecting dopaminergic neurons by inhibiting microglial activation.
Dec 20, 2017
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Article Publish Status
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Pubmed Data
: Int J Mol Sci. 2017 Dec 21 ;19(1). Epub 2017 Dec 21. PMID:
29267220
Article Published Date
: Dec 20, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Gallic acid attenuated lipopolysaccharide-induced neuroinflammation.
Dec 11, 2019
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Pubmed Data
: Mol Neurobiol. 2019 Dec 12. Epub 2019 Dec 12. PMID:
31832973
Article Published Date
: Dec 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gallic Acid
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Garden cress extracts have significant hepatoprotective activity in animals.
Dec 02, 2016
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Article Publish Status
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Pubmed Data
: BMC Complement Altern Med. 2016 Dec 3 ;16(1):501. Epub 2016 Dec 3. PMID:
27912738
Article Published Date
: Dec 02, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Garden Cress (Lepidium sativum)
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
Gastrodin attenuation of the inflammatory response in H9c2 cardiomyocytes involves inhibition of NF-κB and MAPKs activation.
Apr 14, 2013
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Pubmed Data
: Biochem Pharmacol. 2013 Apr 15 ;85(8):1124-33. Epub 2013 Jan 29. PMID:
23376120
Article Published Date
: Apr 14, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Gastrodin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Genipin inhibited LPS-induced inflammatory response by activating Nrf2 signalling pathway in BV2 microglia.
Sep 30, 2017
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Pubmed Data
: Neurochem Res. 2017 Oct ;42(10):2769-2776. Epub 2017 May 11. PMID:
28497344
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Genipin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Nitric Oxide Inhibitor
,
Nrf2 activation
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Genipin, a compound found within gardenia fruit, inhibits microglial activation in a mouse model of brain inflammation.
Feb 01, 2010
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Pubmed Data
: Int Immunopharmacol. 2010 Feb 1. Epub 2010 Feb 1. PMID:
20123040
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Gardenia
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Postaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Geraniol alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis.
Sep 18, 2017
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Article Publish Status
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Pubmed Data
: Oncotarget. 2017 Sep 19 ;8(41):71038-71053. Epub 2017 Aug 16. PMID:
29050341
Article Published Date
: Sep 18, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Geraniol
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Geraniol protects against lipopolysaccharide and D-galactosamine-induced fulminant hepatic failure by activating PPARγ.
Feb 28, 2019
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Pubmed Data
: Microb Pathog. 2019 Mar ;128:7-12. Epub 2018 Dec 11. PMID:
30550845
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Geraniol
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginger inhibits micoglial cell activiation associated with brain inflammation.
Jun 01, 2009
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Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2009 Jun;47(6):1190-7. Epub 2009 Feb 20. PMID:
19233241
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Prostaglandin Antagonists
[+]
Ginkgo biloba leaf extract can inhibit the activation of NF-κB and expression of TLR4 induced by lipopolysaccharide.
Nov 30, 2017
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Dec ;14(6):5857-5862. Epub 2017 Oct 16. PMID:
29285133
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Cardiovascular Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection.
Sep 30, 2019
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Article Publish Status
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Pubmed Data
: Neural Regen Res. 2019 Oct ;14(10):1814-1822. PMID:
31169200
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Re may ameliorate inflammation by inhibiting the binding of LPS to TLR4 on macrophages.
Sep 25, 2012
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Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2012 Sep 26 ;60(38):9595-602. Epub 2012 Sep 12. PMID:
22849695
Article Published Date
: Sep 25, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 may be a promising agent for prevention against acute liver injury.
Jun 10, 2018
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Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2018 Jun 11 ;61:266-276. Epub 2018 Jun 11. PMID:
29902710
Article Published Date
: Jun 10, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 alleviates lipopolysaccharide-induced learning and memory impairments.
Sep 29, 2013
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomol Ther (Seoul). 2013 Sep 30 ;21(5):381-90. PMID:
24244826
Article Published Date
: Sep 29, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 ameliorates lipopolysaccharide-induced acute lung injury.
Apr 30, 2016
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Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 May ;34:53-59. Epub 2016 Feb 24. PMID:
26921732
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 attenuates lipopolysaccharide-induced acute lung injury.
Dec 31, 2017
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Article Publish Status
: This is a free article.
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Pubmed Data
: Front Pharmacol. 2018 ;9:850. Epub 2018 Aug 2. PMID:
30116194
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 attenuates microglia activation following systemic lipopolysaccharide treatment in mice.
Dec 31, 2011
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Article Publish Status
: This is a free article.
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Pubmed Data
: Biol Pharm Bull. 2012 ;35(9):1546-52. PMID:
22975507
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside Rg3 was effective in ameliorating depressive-like behavior induced by immune activation.
Aug 15, 2017
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Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Aug 16 ;65(32):6861-6869. Epub 2017 Aug 7. PMID:
28762741
Article Published Date
: Aug 15, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Antidepressive Agents
,
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Ginsenoside-Rg1 from Panax notoginseng has a protective effect against lipopolysaccharide-induced microcirculatory disturbance in rat mesentery.
Jul 19, 2007
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Pubmed Data
: Life Sci. 2007 Jul 19;81(6):509-18. Epub 2007 Jun 28. PMID:
17655881
Article Published Date
: Jul 19, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
,
Panax Notoginseng
Diseases
:
Lipopolysaccharide-Induced Toxicity
[+]
Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia/reperfusion injury.
Nov 15, 2010
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Click here to read the entire abstract
Pubmed Data
: Glia. 2010 Nov 15 ;58(15):1881-92. PMID:
20737476
Article Published Date
: Nov 15, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Glucosamine
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions
:
Enzyme Inhibitors
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Gold nanoparticles exhibited anti-inflammatory and antioxidative activity that reversed morphological alterations induced by lipopolysaccharide.
Sep 09, 2019
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Click here to read the entire abstract
Pubmed Data
: J Biomed Mater Res A. 2019 Sep 10. Epub 2019 Sep 10. PMID:
31502356
Article Published Date
: Sep 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Gold (nanoparticles)
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
[+]
Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression.
Jan 03, 2017
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2017 04 4 ;14(1):74. Epub 2017 Apr 4. PMID:
28376889
Article Published Date
: Jan 03, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Gout
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Proanthocyanidins
[+]
Green mussel extract decreases the production of cytokines associated with inflammation.
Dec 01, 2008
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Click here to read the entire abstract
Pubmed Data
: Eur Ann Allergy Clin Immunol. 2008 Dec;40(4):148-53. PMID:
19227651
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Mussel: Green-lipped (Perna canaliculus)
Diseases
:
Arthritis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 alpha downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Adjuvant-Induced Injury
[+]
Green mussel may have therapeutic value in the treatment of rheumatoid arthritis.
Jan 01, 2007
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Click here to read the entire abstract
Pubmed Data
: BMC Complement Altern Med. 2007;7:20. Epub 2007 Jun 11. PMID:
17562016
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Mussel: Green-lipped (Perna canaliculus)
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-12 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Green tea polyphenols prevent lipopolysaccharide-induced inflammatory liver injury.
Jun 11, 2019
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Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jun 12. Epub 2019 Jun 12. PMID:
31187838
Article Published Date
: Jun 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Herbacetin has potential for use as a therapeutic agent in disorders associated with bone loss.
Apr 14, 2016
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Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Apr 15 ;777:17-25. Epub 2016 Feb 26. PMID:
26923730
Article Published Date
: Apr 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Flaxseed
Diseases
:
Bone Diseases
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
High dose of ascorbic acid may be useful in the treatment of sepsis, at least, by activation of Nrf2/HO-1 signals.
Jun 14, 2015
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Pubmed Data
: Biochem Pharmacol. 2015 Jun 15 ;95(4):279-89. Epub 2015 Apr 17. PMID:
25896849
Article Published Date
: Jun 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Heme oxygenase-1 up-regulation
,
NF-kappaB Inhibitor
,
Nrf2 activation
Additional Keywords
:
Significant Treatment Outcome
[+]
Hirsutanol A could be a useful agent for treating inflammatory diseases.
Jun 16, 2019
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Article Publish Status
: This is a free article.
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Pubmed Data
: Mar Drugs. 2019 Jun 17 ;17(6). Epub 2019 Jun 17. PMID:
31213027
Article Published Date
: Jun 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Red Marine Algae
Diseases
:
Endotoxemia
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
STAT3 Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Homeopathic dilutions of Belladonna and Echinacea have therapeutic value in the treatment of experimental peritonitis.
Oct 01, 2004
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Pubmed Data
: Homeopathy. 2004 Oct;93(4):193-8. PMID:
15532698
Article Published Date
: Oct 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Belladonna
,
Echinacea
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Peritonitis
Therapeutic Actions
:
Homeopathic Treatment
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
Honokiol alleviates sepsis-induced acute kidney injury.
Dec 31, 2018
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Article Publish Status
: This is a free article.
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Pubmed Data
: Cell Mol Biol Lett. 2019 ;24:15. Epub 2019 Feb 22. PMID:
30833971
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Kidney Damage
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Honokiol attenuates lipopolysaccharide-induced acute respiratory distress syndrome.
Oct 27, 2018
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Article Publish Status
: This is a free article.
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Pubmed Data
: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Oct 28 ;43(10):1075-1082. PMID:
30523227
Article Published Date
: Oct 27, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Honokiol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Respiratory Distress Syndrome
Pharmacological Actions
:
Anti-Apoptotic
[+]
Hops (H. lupulus) has anti-inflammatory activity in a mouse model of athritis.
Jul 16, 1996
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Pubmed Data
: Biochem Biophys Res Commun. 1996 Jul 16;224(2):358-61. PMID:
16534727
Article Published Date
: Jul 16, 1996
Study Type
: Animal Study
Additional Links
Substances
:
Hops
Diseases
:
Arthritis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
Additional Keywords
:
Plant Extracts
[+]
Humulus japonicus extracts protect against lipopolysaccharide/d-galactosamine-induced acute liver injury in rats.
Sep 30, 2018
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Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Oct ;21(10):1009-1015. PMID:
30334699
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Hops
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Humulus japonicus inhibits the progression of Alzheimer's disease.
Dec 31, 2016
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Article Publish Status
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Pubmed Data
: Int J Mol Med. 2017 Jan ;39(1):21-30. Epub 2016 Nov 16. PMID:
28004107
Article Published Date
: Dec 31, 2016
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Hops
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Huperzine A inhibits CCL2 production in experimental autoimmune encephalomyelitis.
Jun 30, 2013
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Immunopathol Pharmacol. 2013 Jul-Sep;26(3):757-64. PMID:
24067473
Article Published Date
: Jun 30, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Huperzine
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Multiple Sclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function.
Sep 18, 2016
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Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2016 Sep 19 ;631:70-8. Epub 2016 Jul 9. PMID:
27400829
Article Published Date
: Sep 18, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Huperzine
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Hydroxocobalamin (vitamin B12a) prevents and reverses endotoxin-induced hypotension and mortality in rodents.
Apr 01, 1995
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Pubmed Data
: J Pharmacol Exp Ther. 1995 Apr;273(1):257-65. PMID:
7714773
Article Published Date
: Apr 01, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin B-12
,
Vitamin B-12: Hydroxocobalamin
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
[+]
Hydroxytyrosol attenuates LPS-induced acute lung injury in mice by regulating autophagy and sirtuin expression.
Dec 31, 2016
Add to My Research
Click here to read the entire abstract
Pubmed Data
: Curr Mol Med. 2017 ;17(2):149-159. PMID:
28429673
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Hydroxytyrosol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Autophagy Up-regulation
[+]
Hydroxytyrosol represents an interesting molecule for the development of new nutraceuticals and functional food useful in chronic diseases prevention.
Dec 04, 2018
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Article Publish Status
: This is a free article.
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Pubmed Data
: Molecules. 2018 Dec 5 ;23(12). Epub 2018 Dec 5. PMID:
30563131
Article Published Date
: Dec 04, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Hydroxytyrosol
Diseases
:
DNA damage
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
In vitro macrophage assay predicts the in vivo anti-inflammatory potential of exosomes from human mesenchymal stromal cells.
Jun 13, 2019
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Article Publish Status
: This is a free article.
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Pubmed Data
: Mol Ther Methods Clin Dev. 2019 Jun 14 ;13:67-76. Epub 2018 Dec 15. PMID:
30719485
Article Published Date
: Jun 13, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Additional Keywords
:
Exosomes
[+]
In vivo and in vitro anti-inflammatory effects of water-soluble polysaccharide from Arctium lappa.
Aug 14, 2019
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Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Aug 15 ;135:717-724. Epub 2019 May 23. PMID:
31129217
Article Published Date
: Aug 14, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Burdock
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Polysaccharides
[+]
Indole-3-carbinol inhibits LPS-induced inflammatory response by blocking TRIF-dependent signaling pathway in macrophages.
Jun 30, 2013
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Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2013 Jul ;57:256-61. Epub 2013 Apr 15. PMID:
23597448
Article Published Date
: Jun 30, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Indole-3-Carbinol
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Inhibitory effects of walnut peptides on neuroinflammation and oxidative stress in lipopolysaccharide-induced cognitive impairment.
Feb 25, 2020
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Pubmed Data
: J Agric Food Chem. 2020 Feb 26 ;68(8):2381-2392. Epub 2020 Feb 18. PMID:
32037817
Article Published Date
: Feb 25, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Walnut
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Isofuranodiene from wild celery protects against d-galactosamine/lipopolysacchride induced liver injury and it could be a potential food ingredient for the prevention and treatment of liver diseases.
May 14, 2015
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Pubmed Data
: Nat Prod Res. 2015 May 15:1-4. Epub 2015 May 15. PMID:
25978596
Article Published Date
: May 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Celery
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Diseases
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Dietary Modification
[+]
Isogarcinol is a promising immunosuppressive agent for treating psoriasis.
Jan 31, 2017
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Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Feb 1 ;65(4):846-857. Epub 2017 Jan 24. PMID:
28081600
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Mangosteen
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Psoriasis
Pharmacological Actions
:
Immunomodulatory: Th17 downregulation
,
Immunosuppressive Agents
,
Interferon Gamma Reducer
,
Interleukin-10 upregulation
,
Interleukin-23 Downregulation
,
Interleukin-2 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Isoliquiritigenin attenuates adipose tissue inflammation in vitro and adipose tissue fibrosis.
Mar 14, 2016
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Article Publish Status
: This is a free article.
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Pubmed Data
: Sci Rep. 2016 Mar 15 ;6:23097. Epub 2016 Mar 15. PMID:
26975571
Article Published Date
: Mar 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Isoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity.
Jan 05, 2019
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Article Publish Status
: This is a free article.
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Pubmed Data
: BMC Neurosci. 2019 08 6 ;20(1):41. Epub 2019 Aug 6. PMID:
31387531
Article Published Date
: Jan 05, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Brain Inflammation
,
Cognitive Decline/Dysfunction
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Isoliquiritigenin protects against sepsis-induced lung and liver injury by reducing inflammatory responses.
Jan 04, 2018
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Pubmed Data
: Biochem Biophys Res Commun. 2018 02 5 ;496(2):245-252. Epub 2017 Nov 24. PMID:
29180018
Article Published Date
: Jan 04, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Isoquercitrin attenuates lipopolysaccharide-induced cardiac dysfunction by inhibiting inflammatory responses.
Jan 11, 2018
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Pubmed Data
: Mol Nutr Food Res. 2018 12 ;62(24):e1800955. Epub 2018 Nov 4. PMID:
30359483
Article Published Date
: Jan 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Isoquercitrin
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Kaempferol exhibits anti-pyroptosis activities.
Sep 30, 2019
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Pubmed Data
: Immunopharmacol Immunotoxicol. 2019 Oct ;41(5):538-548. Epub 2019 Sep 24. PMID:
31549524
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Kaempferol
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Krill oil-incorporated liposomes as an effective nanovehicle to ameliorate the inflammatory responses of DSS-induced colitis.
Dec 31, 2018
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Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2019 ;14:8305-8320. Epub 2019 Nov 6. PMID:
31806959
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Krill
,
Omega-3 Fatty Acids
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Lactobacillus gasseri SBT2055 inhibits adipose tissue inflammation and intestinal permeability in mice fed a high-fat diet.
Dec 31, 2015
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Article Publish Status
: This is a free article.
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Pubmed Data
: J Nutr Sci. 2016 ;5:e23. Epub 2016 May 30. PMID:
27293560
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus gasseri
Diseases
:
High Fat Diet
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastroprotective
[+]
Lactobacillus plantarum LC27 and Bifidobacterium longum LC67 mitigate alcoholic steatosis.
Aug 14, 2018
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Article Publish Status
: This is a free article.
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Pubmed Data
: Food Funct. 2018 Aug 15 ;9(8):4255-4265. PMID:
30010169
Article Published Date
