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Liver Damage
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321 Substances Researched for Liver Damage
Name
AC
CK
Focus
Curcumin
59
121
Silymarin
9
26
Ginsenosides
14
25
Milk Thistle
3
24
Nigella sativa (aka Black Seed)
12
22
Polyphenols
12
22
Puerarin
11
21
Thymoquinone
11
20
Resveratrol
8
18
Vitamin C
10
18
Anthocyanins
8
16
Flavonoids
9
16
Melatonin
5
16
Silibinin
4
15
Turmeric
7
14
Dandelion
6
12
Ginger
6
12
Turmeric: Fermented
2
12
Phyllanthus urinaria
2
11
Rose
6
11
Black Tea
5
10
Fermented Foods and Beverages
5
10
Grape Seed Extract
5
10
Sesamol
3
10
Naringenin
5
9
Olive leaf extract
5
9
Sulforaphane
6
9
Alpha-Lipoic Acid
4
8
Asiatic Acid
4
8
Bael
4
8
Beet
4
8
Blueberry
4
8
Camel Milk
4
8
Diallyl sulfide
4
8
Ellagic Acid
4
8
Garlic
4
8
Geraniol
4
8
Honey
4
8
Lycopene
4
8
Mangiferin
3
8
Radish
5
8
Reishi Mushroom
4
8
Sweet Potato: Purple
4
8
Vitamin D
4
8
Astaxanthin
4
7
Fucoidan
4
7
Carrot
3
6
Carvacrol
3
6
Catechin
3
6
Chlorella (Algae)
2
6
Date Seeds
2
6
Dates
3
6
Diosmin
3
6
Fenugreek
3
6
Genistein
3
6
Gingerol
3
6
Ginkgo biloba
2
6
Green Tea
3
6
Jujube
3
6
Lactobacillus plantarum
3
6
Olive Oil
3
6
Pomegranate
3
6
Quercetin
3
6
Royal Jelly
2
6
Sea buckthorn
3
6
Shikonin
3
6
Solanum nigrum (black nightshade)
3
6
Vitamin E
3
6
Yellow Tea
3
6
Zataria multiflora
3
6
Artichoke
3
5
Citrus naringin
3
5
EGCG (Epigallocatechin gallate)
3
5
Fig
3
5
Genipin
3
5
Indole-3-Carbinol
3
5
NAC (N-acetyl-L-cysteine)
3
5
Rosemary
3
5
Apple Polyphenols
2
4
Apricot
2
4
Artesunate
1
4
Ayurvedic formulation: Liv52
2
4
Beeswax
2
4
Berberine
2
4
Berries: All
2
4
Blue Honeysuckle
2
4
Caffeic acid phenethyl ester
2
4
Chlorogenic Acid
2
4
Choline
2
4
Citrus Peel
2
4
Cranberry
2
4
Crocin
2
4
DHA (Docosahexaenoic Acid)
2
4
Dill
2
4
EPA (Eicosapentaenoic Acid)
2
4
Embelia ribes
2
4
Garlic: Aged
2
4
Henna
2
4
Hesperidin
2
4
Hibiscus sabdariffa
2
4
Hu Zhang (Polygonum cuspidatum)
1
4
Hydrogen Water
2
4
Hydroxytyrosol
2
4
Isoliquiritigenin
2
4
Juniper
2
4
Kombucha Tea
3
4
Lactobacillus casei
2
4
Litchi
2
4
Lotus
3
4
Luteolin
2
4
Lychee
2
4
Myricetin
2
4
Noni
2
4
Onion
2
4
Papaya
2
4
Passion Flower
2
4
Phloretin
3
4
Piceatannol
2
4
Pomegranate Peel
2
4
Pomegranate Seed
2
4
Potato
2
4
Propolis: Bee
2
4
Rooibos
2
4
Saffron
2
4
Selenium
2
4
Shiitake Mushroom
2
4
Stevia
2
4
Verbascoside
2
4
White Tea
2
4
Xanthohumol
2
4
Yeast
2
4
Zinc
2
4
Amygdalin (laetrile)
2
3
Chaga Mushroom (Inonotus obliquus)
2
3
D-Limonene
2
3
Lactobacillus fermentum
2
3
Lignans
2
3
Mulberry
2
3
Oleanolic acid
2
3
Thistle
2
3
Ursolic Acid
2
3
Ajwain
1
2
Almond
1
2
Andrographis
1
2
Anise
1
2
Antrodia camphorata
1
2
Apigenin
1
2
Apocynin
1
2
Apples
1
2
Apricot Kernel
1
2
Arginine
1
2
Ashwagandha
1
2
Baccharis trimera
1
2
Bacopa
1
2
Bamboo
1
2
Banana Peel
1
2
Banana Stem
1
2
Barberry
1
2
Barley
1
2
Beta-Caryophyllene
1
2
Bilberry
1
2
Bile salts
1
2
Bitter Apple
1
2
Bitter Melon
1
2
Black Currant
1
2
Black Raspberry
1
2
Black Tea Theaflavins
1
2
Broccoli Sprouts
1
2
Bromelain
1
2
Burdock
1
2
Butterbur
1
2
Cabbage
1
2
Caffeine
1
2
Cannabidiol
1
2
Capsaicin
1
2
Carotenoids
1
2
Celery
1
2
Celosia cristata (cockscomb)
1
2
Centella asiatica
1
2
Chamomile
1
2
Chickpea
1
2
Chicory
1
2
Chrysanthemum Indicum
1
2
Chrysin
1
2
Cinnamon
1
2
Cissus quadrangularis
1
2
Coconut Oil
1
2
Coconut Water
1
2
Coenzyme Q10
1
2
Coffee: Green/Unroasted
1
2
Cordyceps sinensis
1
2
Coriandrum sativum
1
2
Cucurbitacin B
1
2
Cumin
1
2
Cysteine (see N-Acetylcysteine)
1
2
Dibenzoylmethane (DBM)
1
2
Earthworms
1
2
Echinacea
1
2
Eggplant
1
2
Elderberry
1
2
Emodin
1
2
Eriodictyol
1
2
Feverfew
1
2
Fisetin
1
2
Fish Oil
1
2
Flaxseed
1
2
Folic Acid
1
2
Gallic Acid
1
2
Garden Cress (Lepidium sativum)
1
2
Geranium
1
2
Ginseng
1
2
Glycyrrhizin
1
2
Goat Milk
1
2
Goji
1
2
Gold (nanoparticles)
1
2
Goldenseal
1
2
Gotu Kola
1
2
Grape
1
2
Guava
1
2
Guduchi
1
2
Hibiscus rosa-sinensis
1
2
Hops
1
2
Horehound
1
2
Kimchi
1
2
Lactobacillus probiotics
1
2
Lactobacillus reuteri
1
2
Lactobacillus rhamnosus GG
1
2
Lactobacillus salivarius
1
2
Ligustrazine
1
2
Long Pepper
1
2
Loquat Seeds
1
2
Lutein
1
2
Magnesium
1
2
Mango
1
2
Medicinal Mushrooms
1
2
Mint
1
2
Miso
1
2
Modified Arabinoxylan Rice Bran (MGN-3)
1
2
Mucuna pruriens (aka Velvet Beans)
1
2
Myrica rubra
1
2
Nettle
1
2
Nicotinamide adenine dinucleotide (NADH)
1
2
Nobiletin
1
2
Nutmeg
1
2
Oak
1
2
Okra
1
2
Oleuropein
1
2
Olive
1
2
Orange
1
2
Oregano
1
2
Oyster Mushroom
1
2
Paeoniflorin
1
2
Palash
1
2
Palmitoylethanolamide
1
2
Panax Notoginseng
1
2
Peppermint
1
2
Phosphatidylcholine
1
2
Pine Bark Extract
1
2
Piper cubeba (Cubeb)
1
2
Piperine
1
2
Plant Stem Cells
1
2
Proanthocyanidins
1
2
Probiotics
1
2
Prunella vulgaris
1
2
Pterocarpus marsupium
1
2
Pterostilbene
1
2
Pumpkin Seed Oil/Meal
1
2
Purslane
1
2
Raspberry
1
2
Red Cabbage
1
2
Rice Bran
1
2
Rice: Brown
1
2
Rice: Parboiled
1
2
Rosemaric Acid
1
2
Sage
1
2
Saikosaponin
1
2
Salvia miltiorrhiza
1
2
Semecarpus anacardium
1
2
Sesame Seed Oil
1
2
Sessile Joyweed
1
2
Silica Hydride
1
2
Soy
1
2
Spirulina
1
2
Stilbenes
1
2
Strawberry
1
2
Tannic Acid
1
2
Taro
1
2
Taurine
1
2
Thymol
1
2
Tyrosine
1
2
Urine
1
2
Urine: Cow
1
2
Vanillin
1
2
Vitexins
1
2
Walnut
1
2
Water: Deuterium Depleted
1
2
Water: Electrolyzed Reduced
1
2
Yoghurt
1
2
Agrimony
1
1
Allicin
1
1
Astragaloside
1
1
Blackberry
1
1
Caraway
1
1
Coffee
1
1
Coriandor
1
1
Curcuminoids
1
1
Cyperus longus
1
1
Gynostemma
1
1
Haritaki (Terminalia chebula)
1
1
Honokiol
1
1
Kudzu
1
1
Lavender
1
1
Licorice
1
1
Lupeol
1
1
Prickly Pear Cactus
1
1
Rice: Black
1
1
Tanshinone IIA
1
1
Tetrahydrocurcumin
1
1
Vitex negundo
1
1
Wheat Grass
1
1
White Mulberry
1
1
92 Problem Substances Researched for Liver Damage
Name
AC
CK
Focus
Statin Drugs
22
124
Paracetamol
51
95
Acetaminophen
49
91
Simvastatin
9
77
Atorvastatin
12
69
Isoniazid
4
62
Pravastatin
5
45
Bisphenol A
14
41
Fluvastatin
3
40
Lovastatin
7
36
Aflatoxin
10
27
High Fructose Corn Syrup
5
18
Rosuvastatin
4
17
Concanavalin A
7
16
Cadmium
9
15
Tylenol
2
14
Perfluorooctanoic acid (PFOA)
2
12
Tamoxifen
3
12
Fluoroquinolone Antibiotic
1
10
Proton-Pump Inhibitors
1
10
Fluoxetine (trade name Prozac)
4
9
Mercury
3
9
Pesticides
5
9
Morphine
4
8
Tertiary butyl hydroperoxide
6
7
2-chlorobenzylidene malononitrile (CS)
1
6
Arsenic
4
6
Aspartame
3
6
Glyphosate
4
6
Quizalofop-P-ethyl
1
6
Bisphenol S
3
5
Aluminum
2
4
Arsenite
2
4
Benzo(a)pyrene
2
4
Butylated Hydroxytoluene (BHT)
2
4
Cisplatin
2
4
Dichlorvos
2
4
Electronic Cigarettes
2
4
Formaldehyde
2
4
Fructose
2
4
Lead
2
4
Monosodium Glutamate (MSG)
2
4
N-nitrosodiethylamine
2
4
Nanoparticles
2
4
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
2
4
Organophosphate Pesticides
2
4
Perfluorooctane sulfonate (PFOS)
2
4
Rosiglitazone (trade name Avandia)
2
4
Sodium Fluoride
2
4
Acrylamide
2
3
Cerivastatin
1
3
Cholesterol Lowering Drugs
1
3
Fenofibrates
1
3
Fluconazole
1
3
Zinc Oxide
2
3
Aluminum Hydroxide
1
2
Antibiotics
1
2
Arsenic Trioxide
1
2
Brilliant Blue FCF
1
2
Chlorpyrifos
1
2
Cypermethrin
1
2
Dexamethasone
1
2
Diclofenac
1
2
Erythrosine
1
2
Ethylene Glycol
1
2
FD&C Red #40
1
2
Food Colorings
1
2
Insulin
1
2
Metanil-Yellow Dye
1
2
N-nitrosodimethylamine
1
2
Organophosphates
1
2
Paclitaxel
1
2
Ponceau 4R (New Coccine)
1
2
Selective Serotonin Reuptake Inhibitors (SSRIs)
1
2
Sucralose (aka Splenda)
1
2
Sucrose
1
2
Sugar Sweetened Beverages
1
2
Tartrazine (Yellow Food Dye)
1
2
Thiazolidinediones
1
2
Titanium Dioxide
1
2
Titanium Nanoparticles
1
2
Toluene
1
2
Trans Fatty Acids
1
2
Vaccine Adjuvants
1
2
Zoledronic Acid
1
2
Amiodarone
1
1
Dimethoate
1
1
Irinotecan
1
1
Methotrexate
1
1
Parabens
1
1
Triclosan
1
1
Zineb
1
1
6 Problematic Actions Researched for Liver Damage
Name
AC
CK
Focus
Western Diet
2
4
Electromagnetic Fields
1
2
Mobile Phone Radiation
1
2
Vaccination: All
1
2
Vaccination: Hepatitis B
1
2
Nanotechnology
1
1
Research Articles
708
Cumulative Knowledge Score
1145
Overall Research Rating
EXCELLENT
Related Topics
The Following are Sub-Topics of Liver Damage
Liver Damage: Drug-Induced
Liver Damage: Aflatoxin-Induced
Chemically-Induced Liver Damage
Chemotherapy-Induced Liver Toxicity
View the Evidence:
1078 Abstracts with Liver Damage Research
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[+]
Prophylactic therapy of milk thistle on anti-tuberculosis drug-induced liver injury.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Can J Gastroenterol Hepatol. 2019 ;2019:3192351. Epub 2019 Jan 10. PMID:
30733935
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Milk Thistle
Diseases
:
Chemically-Induced Liver Damage
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
The use of statins for LDL suppression is associated with increased risk for cancer.
Jul 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Am Coll Cardiol. 2007 Jul 31 ;50(5):409-18. Epub 2007 Jul 16. PMID:
17662392
Article Published Date
: Jul 31, 2007
Study Type
: Meta Analysis
Additional Links
Diseases
:
Cancers: All
,
Chemically-Induced Liver Damage
,
High Cholesterol
,
Statin-Induced Pathologies
Problem Substances
:
Lovastatin
,
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Acetylcysteine for the treatment of suspected remdesivir-associated acute liver Failure in COVID-19.
Oct 01, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacotherapy. 2020 Oct 2. Epub 2020 Oct 2. PMID:
33006138
Article Published Date
: Oct 01, 2020
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Atorvastatin-induced acute pancreatitis has been reported.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Pharmacother. 2011 Jan ;2(1):40-2. PMID:
21701646
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Pancreatitis
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Autoimmune hepatitis associated with atorvastatin use has been reported.
Aug 01, 2003
Click here to read the entire abstract
Pubmed Data
: Eur J Gastroenterol Hepatol. 2003 Aug ;15(8):921-4. PMID:
12867804
Article Published Date
: Aug 01, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Autoimmune
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Bisphenol A was detected above the detection limit in all samples in individuals affected by non-alcoholic fatty liver disease.
Jun 04, 2017
Click here to read the entire abstract
Pubmed Data
: J Pharm Biomed Anal. 2017 Jun 5 ;140:105-112. Epub 2017 Mar 10. PMID:
28346880
Article Published Date
: Jun 04, 2017
Study Type
: Human In Vitro, Human Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Additional Keywords
:
Bisphenol A
,
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
[+]
Combined treatment including melatonin resulted in the improvement of general conditions in 81.7% of the patients
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Klin Med (Mosk). 2013 ;91(3):50-3. PMID:
23789453
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Melatonin
Diseases
:
Chemically-Induced Liver Damage
Additional Keywords
:
Plant Extracts
[+]
Drug-induced liver toxicity (particularly acetaminophen-induced liver toxicity) has replaced viral hepatitis as the most single frequent cause of acute liver failutre in ubran
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Z Gastroenterol. 2009 Sep;47(9):807-13. Epub 2009 Sep 11. PMID:
19750427
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Tylenol
[+]
Exposure of children to even low doses of BPA may adversely affect later liver function.
Nov 16, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Res. 2017 Nov 17 ;161:195-201. Epub 2017 Nov 17. PMID:
29156342
Article Published Date
: Nov 16, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
[+]
Fermented turmeric powder is well-tolerated and effective in subjects with elevated alanine transaminase levels.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2013 ;13:58. Epub 2013 Mar 8. PMID:
23497020
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Turmeric: Fermented
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Phytotherapy
[+]
Fluoroquinolone therapy and idiosyncratic acute liver injury: a population-based study.
Aug 12, 2012
Click here to read the entire abstract
Pubmed Data
: CMAJ. 2012 Aug 13. Epub 2012 Aug 13. PMID:
22891208
Article Published Date
: Aug 12, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Fluoroquinolone Antibiotic
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Fluvastatin has been linked to adverse hepatic reactions.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Drug Saf. 2006 ;29(12):1163-72. PMID:
17147462
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Nutrient Depletion: Statin Drugs
Problem Substances
:
Fluvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Med Hypotheses. 2019 Mar ;124:40-41. Epub 2019 Feb 4. PMID:
30798914
Article Published Date
: Feb 28, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
Problem Substances
:
High Fructose Corn Syrup
[+]
Isoniazid has been associated with grade 3 or 4 liver failure in 1.4%-5.2% of patients being treated for latent tuberculosis infection.
Dec 15, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Infect Dis. 2009 Dec 15;49(12):1883-9. PMID:
19911936
Article Published Date
: Dec 15, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Problem Substances
:
Isoniazid
[+]
Isoniazid treatment in latent tuberculosis infection may be associated with moderate-to-severe liver damage without symptoms.
Jul 01, 2005
Click here to read the entire abstract
Pubmed Data
: Chest. 2005 Jul;128(1):116-23. PMID:
16002924
Article Published Date
: Jul 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Additional Keywords
:
Iatrogenic Disease
Problem Substances
:
Isoniazid
[+]
Liver failure and damage are rare but severe unintended consequences of statin drug use.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Hepatol. 2011 Aug 31. Epub 2011 Aug 31. PMID:
21889469
Article Published Date
: Aug 31, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage
,
Liver Disease
,
Liver Failure: Drug Induced
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Fluvastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
More than half of patients who present at the hospital with acetaminophen-induced liver damage or liver failure have undetectable levels of acetaminophen.
Feb 04, 2019
Click here to read the entire abstract
Pubmed Data
: Clin Gastroenterol Hepatol. 2019 Feb 5. Epub 2019 Feb 5. PMID:
30731196
Article Published Date
: Feb 04, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
[+]
NAC has a therapeutic effect on hepatotoxicity in children being treated with chemotherapeutic agents.
Mar 31, 2020
Click here to read the entire abstract
Pubmed Data
: Ir J Med Sci. 2020 Apr 1. Epub 2020 Apr 1. PMID:
32239424
Article Published Date
: Mar 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
NAC should be considered in management of anti-tuberculosis drug induced liver injury.
Aug 25, 2020
Click here to read the entire abstract
Pubmed Data
: Clin Infect Dis. 2020 Aug 26. Epub 2020 Aug 26. PMID:
32845997
Article Published Date
: Aug 25, 2020
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage: Drug-Induced
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Perfluorooctanoic acid has hepatotoxic effects.
Jul 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Health Perspect. 2016 Aug ;124(8):1227-33. Epub 2016 Mar 15. PMID:
26978841
Article Published Date
: Jul 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Perfluorinated Compound Toxicity
Problem Substances
:
Perfluorooctanoic acid (PFOA)
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Phyllanthus Urinaria is useful in preventing or delaying the development of HBV-associated cirrhosis to hepatocellular carcinoma.
Mar 24, 2013
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2013 Mar 25. Epub 2013 Mar 25. PMID:
23529834
Article Published Date
: Mar 24, 2013
Study Type
: Human Study
Additional Links
Substances
:
Phyllanthus urinaria
Diseases
:
Liver Cancer: Hepatitis B Associated
,
Liver Cancer: Prevention
,
Liver Cirrhosis
,
Liver Damage
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Significant Treatment Outcome
[+]
Prevalence of Vitamin-D deficiency is related to severity of liver damage in Hepatitis-C patients.
Feb 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pak J Med Sci. 2020 Mar-Apr;36(3):445-450. PMID:
32292450
Article Published Date
: Feb 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Hepatitis C
,
Liver Damage
,
Vitamin D Deficiency
Therapeutic Actions
:
Sunlight exposure
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Increased Risk
[+]
Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Clin Oncol. 2017 Nov ;7(5):891-896. Epub 2017 Sep 1. PMID:
29142752
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Colorectal Cancer
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Severe liver toxicity requiring discontinuation occurs in 5% of simvastatin-treated patients and 4.5% of pravastatin-treated patients.
Jan 01, 1992
Click here to read the entire abstract
Pubmed Data
: Minerva Gastroenterol Dietol. 1992 Jan-Mar;38(1):41-4. PMID:
1520752
Article Published Date
: Jan 01, 1992
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Statin-Induced Pathologies
Problem Substances
:
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Severe, even fatal liver injuries have resulted as a consequence of isoniazid treatment in individuals with latent tuberculosis.
Mar 05, 2010
Click here to read the entire abstract
Pubmed Data
: MMWR Morb Mortal Wkly Rep. 2010 Mar 5;59(8):224-9. PMID:
20203555
Article Published Date
: Mar 05, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Additional Keywords
:
Iatrogenic Disease
Problem Substances
:
Isoniazid
[+]
Silibinin could be beneficial in preventing drug-induced liver injury in tuberculosis treatments.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015 ;8(3):4320-7. Epub 2015 Mar 15. PMID:
26064348
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Silymarin has an efficacy to prevent liver injury from standard combined antituberculosis drugs without significant adverse effects.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15(1):334. Epub 2015 Sep 23. PMID:
26400476
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Silymarin
Diseases
:
Liver Damage: Drug-Induced
,
Tuberculosis
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Tamoxifen treatment for breast cancer may result in fatty liver.
Nov 01, 2000
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2000 Nov-Dec;7(6):1299-304. PMID:
11032933
Article Published Date
: Nov 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
Additional Keywords
:
Drug: 5-flourouracil
,
Drug: Doxorubicin
,
Drug: Tamoxifen
Problem Substances
:
Tamoxifen
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
There is evidence that aflatoxin exposure plays a role in the pathogenesis of liver cancer in the US population.
Jan 01, 1999
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 1999 ;35(1):27-33. PMID:
10624703
Article Published Date
: Jan 01, 1999
Study Type
: Human Study
Additional Links
Diseases
:
Aflatoxicosis
,
Liver Cancer
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Tumor Suppressor Protein p53 Upregulation
Problem Substances
:
Aflatoxin
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Treatment with proton pump inhibitors is associated with increased mortality in patients with pyogenic liver abscess.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: Aliment Pharmacol Ther. 2018 Mar ;47(6):801-808. Epub 2018 Jan 12. PMID:
29327781
Article Published Date
: Feb 28, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Liver Damage
Additional Keywords
:
Risk Factors
Problem Substances
:
Proton-Pump Inhibitors
[+]
Unintended consequences of statin drug use are increased risk of esophageal cancer, kidney failure, cataract, liver dysfunction and myopathies.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: BMJ. 2010;340:c2197. Epub 2010 May 20. PMID:
20488911
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Cardiovascular Diseases
,
Cataract
,
Chemically-Induced Liver Damage
,
Esophageal Cancer
,
Kidney Failure
,
Myopathies
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Fluvastatin
,
Pravastatin
,
Rosuvastatin
,
Simvastatin
,
Statin Drugs
[+]
Zinc and vitamin C oral supplementation for 1 month had an ameliorative effect on the hepatotoxicity of Aflatoxin B1 in wheat miller workers.
Jun 12, 2019
Click here to read the entire abstract
Pubmed Data
: J Complement Integr Med. 2019 Jun 13 ;16(4). Epub 2019 Jun 13. PMID:
31199767
Article Published Date
: Jun 12, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
,
Zinc
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
Problem Substances
:
Aflatoxin
[+]
Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue.
Aug 11, 2019
Click here to read the entire abstract
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2019 Aug 12. Epub 2019 Aug 12. PMID:
31403256
Article Published Date
: Aug 11, 2019
Study Type
: Animal Study, Human In Vitro
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
[+]
Curcumin could modulate hepatocyte epithelial-mesenchymal transition implicated in treatment of liver fibrosis.
Aug 23, 2015
Click here to read the entire abstract
Pubmed Data
: Lab Invest. 2015 Aug 24. Epub 2015 Aug 24. PMID:
26302188
Article Published Date
: Aug 23, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Mangiferin could ameliorate methylmercury mediated mitochondrial dysfunction in human hepatic cells in vitro.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2017 Feb ;32(2):630-644. Epub 2016 Mar 28. PMID:
28071871
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Mangiferin
Diseases
:
Chemically-Induced Liver Damage
,
Mercury Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Methylmercury
Problem Substances
:
Mercury
[+]
A case of hepatitis caused by simvastatin has been reported.
Jan 01, 1991
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Clin Biol. 1991 ;15(1):94-5. PMID:
2010080
Article Published Date
: Jan 01, 1991
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
,
Simvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
A case report of fluoxetine-induced Stevens-Johnson syndrome and liver injury.
Jan 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Pharm Ther. 2019 Feb ;44(1):115-118. Epub 2018 Oct 8. PMID:
30296343
Article Published Date
: Jan 31, 2019
Study Type
: Human: Case Report
Additional Links
Diseases
:
Liver Damage: Drug-Induced
,
Stevens-Johnson Syndrome
Problem Substances
:
Fluoxetine (trade name Prozac)
[+]
Acute cholestatic hepatitis associated with atorvastatin use has been reported.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Hepatol. 2006 Jan ;29(1):21-4. PMID:
16393626
Article Published Date
: Jan 01, 2006
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis associated with pravastatin has been reported.
May 01, 1999
Click here to read the entire abstract
Pubmed Data
: Am J Gastroenterol. 1999 May ;94(5):1388-90. PMID:
10235223
Article Published Date
: May 01, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Pravastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis induced by cerivastatin has been reported.
May 18, 2002
Click here to read the entire abstract
Pubmed Data
: Med Clin (Barc). 2002 May 18 ;118(18):717. PMID:
12042141
Article Published Date
: May 18, 2002
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Cerivastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis induced by fenofibrate has been reported.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Clin Pharm Ther. 2009 Oct;34(5):599-602. PMID:
19744016
Article Published Date
: Oct 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Toxicity
,
Hepatitis
Problem Substances
:
Fenofibrates
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute exposure to CS tear gas has been reported to cause several health problems in an individual.
Dec 26, 1981
Click here to read the entire abstract
Pubmed Data
: Schweiz Med Wochenschr. 1981 Dec 26 ;111(52):2056-60. PMID:
6800031
Article Published Date
: Dec 26, 1981
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Heart Failure
,
Liver Damage
,
Pneumonia
Problem Substances
:
2-chlorobenzylidene malononitrile (CS)
[+]
Acute hepatitis induced by lovastatin has been reported.
Sep 01, 1994
Click here to read the entire abstract
Pubmed Data
: Dig Dis Sci. 1994 Sep ;39(9):2032-3. PMID:
8082513
Article Published Date
: Sep 01, 1994
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
After taking 30 mg artichoke leaf extract tea 3 times a day, patients bilirubin levels significantly declined at the end of the first week and all liver function tests were normalized within 2 months.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Case Reports Hepatol. 2014 ;2014:697359. Epub 2014 Sep 3. PMID:
25374729
Article Published Date
: Dec 31, 2013
Study Type
: Human: Case Report
Additional Links
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Significant Treatment Outcome
Problem Substances
:
Fluconazole
[+]
Atorvastatin has been reported to have caused severe acute hepatitis with symptomatic cholestasis for more than 3 months and bile duct injury.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Acta Gastroenterol Belg. 2008 Jul-Sep;71(3):318-20. PMID:
19198578
Article Published Date
: Jul 01, 2008
Study Type
: Human: Case Report
Additional Links
Diseases
:
Bile Duct Injury
,
Chemically-Induced Liver Damage
,
Cholestasis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Atorvastatin-induced cholestatic hepatitis in a young woman with systemic lupus erythematosus has been reported.
Aug 09, 1999
Click here to read the entire abstract
Pubmed Data
: Arch Intern Med. 1999 Aug 9-23;159(15):1811-2. PMID:
10448788
Article Published Date
: Aug 09, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Cholestatic jaundice during lovastatin medication has been reported.
May 10, 1991
Click here to read the entire abstract
Pubmed Data
: Dtsch Med Wochenschr. 1991 May 10 ;116(19):739-40. PMID:
2026107
Article Published Date
: May 10, 1991
Study Type
: Human: Case Report
Additional Links
Diseases
:
Cholestasis
,
Jaundice
,
Liver Damage: Drug-Induced
,
Statin-Induced Pathologies
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Cholestatic jaundice induced by atorvastatin has been observed.
Jul 01, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Isr Med Assoc J. 2009 Jul ;11(7):440-1. PMID:
19911499
Article Published Date
: Jul 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Autoimmune Diseases
,
Chemically-Induced Liver Damage
,
Hepatitis: Cholestatic
,
Jaundice
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Hepatitis associated with treatment with lovastatin has been reported.
Mar 01, 1998
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Hepatol. 1998 Mar ;21(3):127-8. PMID:
9607293
Article Published Date
: Mar 01, 1998
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Liver fibrosis has been attributed to lipid lowering medications.
Sep 01, 2001
Click here to read the entire abstract
Pubmed Data
: J Intern Med. 2001 Sep ;250(3):249-54. PMID:
11555130
Article Published Date
: Sep 01, 2001
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Liver Cirrhosis
,
Liver Fibrosis
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Cholesterol Lowering Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Lovastatin monotherapy has been reported to have been a cause of rhabdomyolysis, acute renal failure and hepatopathy.
Jul 01, 1997
Click here to read the entire abstract
Pubmed Data
: Jpn Heart J. 1997 Jul ;38(4):541-5. PMID:
9350151
Article Published Date
: Jul 01, 1997
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Failure: Acute
,
Rhabdomyolysis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Nephrotoxic
[+]
Mixed cholestatic/hepatocellular liver injury induced by the herbicide quizalofop-p-ethyl has been reported.
Oct 01, 2007
Click here to read the entire abstract
Pubmed Data
: Environ Health Perspect. 2007 Oct ;115(10):1479-81. PMID:
17938739
Article Published Date
: Oct 01, 2007
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
Problem Substances
:
Quizalofop-P-ethyl
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
N-acetylcysteine in the management of acute liver failure from sickle cell hepatic crisis.
Jul 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ACG Case Rep J. 2019 Aug ;6(8):e00161. Epub 2019 Aug 21. PMID:
31737700
Article Published Date
: Jul 31, 2019
Study Type
: Human: Case Report
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Liver Damage
,
Sickle Cell Anemia
Pharmacological Actions
:
Hepatoprotective
[+]
Novel use of N-acetylcysteine in management of tyrosine kinase inhibitor induced acute liver injury.
Nov 26, 2019
Click here to read the entire abstract
Pubmed Data
: Cureus. 2019 Nov 27 ;11(11):e6251. Epub 2019 Nov 27. PMID:
31890447
Article Published Date
: Nov 26, 2019
Study Type
: Human: Case Report
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Reversible acute hepatitis induced by rosuvastatin has been reported.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: South Med J. 2008 Jul ;101(7):768. PMID:
19209117
Article Published Date
: Jul 01, 2008
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Statin-Induced Pathologies
Problem Substances
:
Rosuvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Rosuvastatin-associated hepatitis with autoimmune features has been reported.
May 01, 2005
Click here to read the entire abstract
Pubmed Data
: Eur J Gastroenterol Hepatol. 2005 May ;17(5):589-90. PMID:
15827453
Article Published Date
: May 01, 2005
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Autoimmune
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Rosuvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Simvastatin has been reported to cause cholestatic hepatitis.
Apr 01, 1991
Click here to read the entire abstract
Pubmed Data
: Recenti Prog Med. 1991 Apr ;82(4):233-5. PMID:
1857844
Article Published Date
: Apr 01, 1991
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Elevated: ALT
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Simvastatin has been reported to cause liver lesions.
Apr 13, 1996
Click here to read the entire abstract
Pubmed Data
: Ned Tijdschr Geneeskd. 1996 Apr 13 ;140(15):846-8. PMID:
8668280
Article Published Date
: Apr 13, 1996
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Jaundice
,
Liver Damage
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
[+]
Simvastatin-ezetimibe-induced hepatic failure necessitating liver transplantation has been reported.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2008 Sep ;28(9):1188-93. PMID:
18752389
Article Published Date
: Sep 01, 2008
Study Type
: Human: Case Report
Additional Links
Diseases
:
Liver Damage: Drug-Induced
,
Organ Transplantation: Liver
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Ameliorative effect of kefir against γ-irradiation induced liver injury in male rats: impact on oxidative stress and inflammation.
Jun 24, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2020 Jun 25. Epub 2020 Jun 25. PMID:
32588307
Article Published Date
: Jun 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Kefir
Diseases
:
Liver Damage
,
Radiation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Radioprotective
[+]
Anti-inflammatory and antioxidant effects of Apium graveolens L. extracts mitigate against fatal acetaminophen-induced acute liver toxicity.
Jul 25, 2020
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2020 Jul 26:e13399. Epub 2020 Jul 26. PMID:
32713084
Article Published Date
: Jul 25, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Celery
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
[+]
Co-administration of N-Acetylcysteine and Acetaminophen efficiently blocks Acetaminophen toxicity.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2015 Aug ;76(5):251-8. Epub 2015 Aug 7. PMID:
26250417
Article Published Date
: Jul 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Effects of grape juice, red wine and resveratrol on liver parameters of rat submitted high-fat diet.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: An Acad Bras Cienc. 2020 ;92(2):e20191230. Epub 2020 Aug 10. PMID:
32785427
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Red Wine
,
Resveratrol
Diseases
:
High Fat Diet
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
F. religisoa protects against isoniazid, rifampicin and paracetamol induced oxidative liver injury in rats.
Sep 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacognosy Res. 2013 Oct ;5(4):271-6. PMID:
24174821
Article Published Date
: Sep 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Fig
Diseases
:
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Isoniazid
,
Paracetamol
[+]
Melittin ameliorates inflammation in mouse acute liver failure via inhibition of PKM2-mediated Warburg effect.
Sep 15, 2020
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2020 Sep 16. Epub 2020 Sep 16. PMID:
32939034
Article Published Date
: Sep 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Liver Damage
,
Liver Failure: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
[+]
Purple grape juices prevent pentylenetetrazol-induced oxidative damage in the liver and serum of Wistar rats.
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2013 Feb ;33(2):120-5. Epub 2013 Jan 17. PMID:
23399662
Article Published Date
: Jan 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Lipid Peroxidation
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice
Jun 11, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Health Prev Med. 2017 Jun 12 ;22(1):54. Epub 2017 Jun 12. PMID:
29165178
Article Published Date
: Jun 11, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
The hepatoprotective effect of prazosin is comparable to N- acetylcysteine against acetaminophen induced hepatotoxicity.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: J Ayub Med Coll Abbottabad. 2020 Jan- Mar;32(1):28-32. PMID:
32468750
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
The protective effect of chrysin against carbon tetrachloride-induced kidney and liver tissue damage.
Apr 29, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2020 Apr 30:1-12. Epub 2020 Apr 30. PMID:
32349632
Article Published Date
: Apr 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
[+]
"Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury."
Oct 01, 2012
Click here to read the entire abstract
Pubmed Data
: Toxicol Lett. 2012 Oct 2 ;214(1):9-18. Epub 2012 Aug 10. PMID:
22902350
Article Published Date
: Oct 01, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Chimera
[+]
"Vitamin E protects against oxidative damage caused by formaldehyde in the liver and plasma of rats."
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2006 Oct ;290(1-2):61-7. Epub 2006 Aug 26. PMID:
16937016
Article Published Date
: Oct 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Chemically-Induced Liver Damage
,
Formaldehyde Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Formaldehyde
[+]
6-gingerol, an active ingredient of ginger, protects acetaminophen-induced liver damage in mice.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Zhong Xi Yi Jie He Xue Bao. 2011 Nov ;9(11):1264-9. PMID:
22088594
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
A curcumin-phospholipid complex works synergistically to protect the livers of rats following chemical exposure.
Feb 07, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Pharm. 2007 Feb 7;330(1-2):155-63. Epub 2006 Sep 23. PMID:
17112692
Article Published Date
: Feb 07, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Phosphatidylcholine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A maple syrup extract alleviates liver injury in type 2 diabetic model mice.
Oct 23, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res. 2019 Oct 24 ;73:97-101. Epub 2019 Oct 24. PMID:
31945627
Article Published Date
: Oct 23, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Maple Syrup
Diseases
:
Diabetes Mellitus: Type 2
,
Diabetic Complications
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A new possible mechanism by which punicalagin protects against liver injury induced by type 2 diabetes mellitus.
Nov 06, 2019
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2019 Nov 7. Epub 2019 Nov 7. PMID:
31698901
Article Published Date
: Nov 06, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Diabetes Mellitus: Type 2
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A phenolics rich extract of ginger had protective effects against Aflatoxin B1-induced oxidative stress and hepatotoxicity.
May 01, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 May 2 ;91:415-424. Epub 2017 May 2. PMID:
28475920
Article Published Date
: May 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Gingerol
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 inducer
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Aflatoxin
[+]
A water extract of the leaves of Z. jujuba is efficacious for prevention and treatment of carbon tetrachloride induced hepatic injury in mice.
Feb 21, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 Feb 22 ;8(2):816-822. PMID:
28124048
Article Published Date
: Feb 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Jujube
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
A. catechu seed extract is a promising agent for protecting liver from acetaminophen induced hepatotoxicity.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2018 Dec ;108:838-844. Epub 2018 Sep 24. PMID:
30372895
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Acacia catechu
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
A. cerana honey can prevent bromobenzene-induced hepatic damage in mice.
Jan 15, 2018
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2018 Jan 16. Epub 2018 Jan 16. PMID:
29337369
Article Published Date
: Jan 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A. graveolens extract showed an ameliorative effect against liver oxidative stress in adjuvant-induced arthritis.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Prev Nutr Food Sci. 2016 Jun ;21(2):79-84. Epub 2016 Jun 30. PMID:
27390722
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Celery
Diseases
:
Arthritis
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A. lappa could protect the liver cells from carbon tetrachloride or acetaminophen-induced liver damages.
Dec 31, 1999
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2000 ;28(2):163-73. PMID:
10999435
Article Published Date
: Dec 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Burdock
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
A. marmelos attenuates carbon tetrachloride-mediated hepatic oxidative stress, toxicity, tumor promotion.
Mar 31, 2009
Click here to read the entire abstract
Pubmed Data
: J Enzyme Inhib Med Chem. 2009 Apr ;24(2):320-7. PMID:
18830880
Article Published Date
: Mar 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Liver Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
A. sessilis has hepatoprotective activity against carbon tetrachloride liver damage.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Indian J Clin Biochem. 2018 Apr ;33(2):190-195. Epub 2017 May 18. PMID:
29651210
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Sessile Joyweed
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Acacia catechu extract affords hepato-protection against DMBA in rats through modulation of phase I, II and anti-oxidative enzymes.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(2):e90083. Epub 2014 Feb 27. PMID:
24587216
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Acacia catechu
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Phase I Detoxification Enzyme Inducer
,
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Plant Extracts
[+]
Accumulation of polystyrene microplastics in juvenile Chinese mitten crab and oxidative stress effects in the liver.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Aquat Toxicol. 2018 Jul ;200:28-36. Epub 2018 Apr 24. PMID:
29709883
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Liver Damage
,
Oxidative Stress
Additional Keywords
:
Microplastic
[+]
Acetaminophen could cause transient mitochondrial dysfunction that may synergize with other stresses to promote liver damage and steatosis.
Dec 30, 2015
Click here to read the entire abstract
Pubmed Data
: Toxicol Sci. 2015 Dec 31. Epub 2015 Dec 31. PMID:
26721299
Article Published Date
: Dec 30, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
,
Mitochondrial Dysfunction
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Acteoside has a protective and therapeutic effect on LPS-induced immunological liver injury in mice.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2009 Nov ;75(14):1463-9. Epub 2009 Jun 22. PMID:
19548187
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2018 Jan ;54:125-130. Epub 2017 Nov 9. PMID:
29128856
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet.
Jul 22, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jul 23. Epub 2019 Jul 23. PMID:
31334539
Article Published Date
: Jul 22, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Mango leaf
Diseases
:
Inflammation
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
NF-kappaB Inhibitor
Anti Therapeutic Actions
:
Western Diet
[+]
Administration of silymarin significantly prevented acute liver injury induced by restraint stress.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2016 ;21(4). Epub 2016 Apr 1. PMID:
27043523
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Silymarin
Diseases
:
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Administration of Zataria multiflora extract and carvacrol could reduce the oxidative damage in the rat liver induced by doxorubicin.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed J. 2018 Dec ;41(6):340-347. Epub 2019 Jan 11. PMID:
30709575
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
,
Zataria multiflora
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Aegle marmelos methanol extract could protect against carbon tetrachloride.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Rep. 2018 ;5:1161-1168. Epub 2018 Oct 13. PMID:
30627516
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Aerobic exercise and eugenol supplementation ameliorated liver injury induced by chlorpyrifos.
Feb 24, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2020 Feb 25. Epub 2020 Feb 25. PMID:
32096903
Article Published Date
: Feb 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Eugenol
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide Toxicity
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Chlorpyrifos
[+]
Aged black garlic has hepatoprotective effects and suggests that supplementation might be a good adjuvant therapy for the management of liver injury.
Feb 28, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Res. 2014 Mar ;30(1):49-54. PMID:
24795800
Article Published Date
: Feb 28, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Fatty Liver
,
High Fat Diet
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Aged garlic extract supplementation could be used to reverse the hepatic injury following ethephon exposure through its antioxidant capacity.
Dec 20, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2019 Dec 21. Epub 2019 Dec 21. PMID:
31865585
Article Published Date
: Dec 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Ajwa date extract afforded significant protection against carbon tetrachloride-induced hepatocellular injury.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2017 Nov ;30(6):2183-2191. PMID:
29175788
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
[+]
Ajwain attenuates chemically-induced liver damage in rats.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2009 Feb;47(2):279-82. Epub 2008 Oct 4. PMID:
18940228
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ajwain
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Almond skin extract has hepatoprotective properties against chemically-induced liver cell damage.
Apr 29, 2010
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2010 Apr 29;185(2):101-9. Epub 2010 Mar 6. PMID:
20211157
Article Published Date
: Apr 29, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Almond
,
Catechin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Alpha lipoic acid possess protective effects against chlorpyrifos induced liver injury.
Feb 22, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2018 Feb 23 ;59:17-23. Epub 2018 Feb 23. PMID:
29500983
Article Published Date
: Feb 22, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Chlorpyrifos
,
Pesticides
[+]
Alpha-linolenic acid helped in controlling glycaemia in rats induced to T2DM.
Nov 05, 2020
Click here to read the entire abstract
Pubmed Data
: J Bioenerg Biomembr. 2020 Nov 6. Epub 2020 Nov 6. PMID:
33156468
Article Published Date
: Nov 05, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha Linolenic Acid
Diseases
:
Diabetes Mellitus: Type 2
,
Liver Damage
,
Mitochondrial Dysfunction
Additional Keywords
:
Risk Factors
[+]
Alpha-lipoic acid ameliorates sodium valproate-induced liver injury.
Apr 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Vet World. 2020 May ;13(5):963-966. Epub 2020 May 22. PMID:
32636594
Article Published Date
: Apr 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Alpha-lipoic acid protected against valproic acid-induced liver damage and hematological disturbance.
Dec 03, 2020
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2020 Dec 4. Epub 2020 Dec 4. PMID:
33275538
Article Published Date
: Dec 03, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alpha-Lipoic acid protects against microcystin-LR induced hepatotoxicity through regeneration of glutathione via activation of Nrf2
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2020 Jul ;35(7):738-746. Epub 2020 Feb 15. PMID:
32061150
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
[+]
Alpha-mangostin remodels visceral adipose tissue inflammation to ameliorate age-related metabolic disorders.
Dec 05, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging (Albany NY). 2019 Dec 6 ;11(23):11084-11110. Epub 2019 Dec 6. PMID:
31806859
Article Published Date
: Dec 05, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Mangosteen
Diseases
:
Aging
,
Inflammation
,
Liver Damage
,
Metabolic Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
MicroRNA modulator
[+]
Ameliorative effects of honey, propolis, pollen, and royal jelly mixture against chronic toxicity of sumithion insecticide.
Jun 04, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Jun 5 ;25(11). Epub 2020 Jun 5. PMID:
32517066
Article Published Date
: Jun 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Bee Pollen
,
Bee Propolis
,
Honey
,
Royal Jelly
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Pesticides
[+]
Ameliorative effects of Moringa oleifera leaf extract on levofloxacin-induced hepatic toxicity.
Feb 19, 2019
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2019 Feb 20:1-7. Epub 2019 Feb 20. PMID:
30782023
Article Published Date
: Feb 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Antibiotic Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-10 upregulation
Problem Substances
:
Fluoroquinolone Antibiotic
,
Levofloxacin
[+]
Ameliorative impact of cold-pressed Rosmarinus officinalis oil against liver toxicity and genotoxic effects in streptozotocin-induced diabetes mellitus.
Jun 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Jul ;43(7):e12905. Epub 2019 May 20. PMID:
31353725
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Rosemary
Diseases
:
Diabetic Complications
,
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
[+]
Amygdalin (Vitamin B17) pretreatment attenuates experimentally induced acute autoimmune hepatitis.
May 14, 2019
Click here to read the entire abstract
Pubmed Data
: Ann Anat. 2019 May 15 ;224:124-132. Epub 2019 May 15. PMID:
31100343
Article Published Date
: May 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin (laetrile)
Diseases
:
Hepatitis: Autoimmune
,
Hepatitis: Lectin-Induced (concanavalin)
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Immunomodulatory
Problem Substances
:
Concanavalin A
[+]
Amygdalin reduces lipopolysaccharide-induced chronic liver injury.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):2688-2697. PMID:
31257932
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin (laetrile)
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
An anthocyanin-rich extract of Hibiscus sabdariffa calyces had hepatoprotective activity.
Aug 25, 2016
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2016 Aug 26:1-10. Epub 2016 Aug 26. PMID:
27564372
Article Published Date
: Aug 25, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Hibiscus sabdariffa
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
An extract of P. guajava leaves and its isolated quercetin fraction have a hypolipidemic activity against carbon tetrachloride induced hepatotoxicity.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacogn Mag. 2018 Jan-Mar;14(53):4-8. Epub 2018 Feb 20. PMID:
29576694
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Guava
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
An extract of P. vulgaris alleviated carbon tetrachloride-induced hepatic in vivo.
Oct 12, 2015
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2015 Oct 13. Epub 2015 Oct 13. PMID:
26460672
Article Published Date
: Oct 12, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Prunella vulgaris
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-4 downregulation
,
Interleukin-8 downregulation
,
MicroRNA modulator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
An extract of Stevia rebaudiana leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Nov ;95:1040-1050. Epub 2017 Sep 13. PMID:
28922721
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Stevia
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
An isoflavonoid from seeds of Lepidium sativum L. has a protective effect on hepatotoxicity induced by paracetamol.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2014 ;19(10):15440-51. Epub 2014 Sep 26. PMID:
25264831
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Garden Cress (Lepidium sativum)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
An unexpected role of cholesterol sulfotransferase and its regulation in sensitizing mice to acetaminophen induced liver injury.
Apr 02, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Pharmacol. 2019 Apr 3. Epub 2019 Apr 3. PMID:
30944208
Article Published Date
: Apr 02, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Andrographolide, a compound found within andrographis, has anti-tumor activity in chemically-induced liver damage.
Jun 01, 2005
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2005 Jun;21(6):756-61. PMID:
19679627
Article Published Date
: Jun 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2018 May ;111:1133-1139. Epub 2018 Feb 19. PMID:
29415408
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Angelica sinensis pretreatment could effectively guard the liver and kidney of mice from D-galactose-induced injury.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Sep ;21(9):887-898. Epub 2018 Aug 15. PMID:
30109956
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Angelica
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Kidney Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Renoprotective
[+]
Anise seed possesses protective effects against carbon tetrachloride (CCl4)-induced toxicity.
Jan 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2015 Feb ;18(2):205-11. PMID:
25825639
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Anise
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Essential Oils
[+]
Anthocyanin-rich black currant extract affords chemoprevention against chemically-induced liver cancer in rats.
Jan 07, 2011
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2011 Jan 7. Epub 2011 Jan 7. PMID:
21216582
Article Published Date
: Jan 07, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Black Currant
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
Pharmacological Actions
:
Bax/Bcl2 ratio: Increase
,
Chemopreventive
[+]
Anthocyanins from bilberry extract have strong antioxidant properties and therefore can be considered as powerful hepatoprotectives in natural products.
Jul 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jul 15 ;157:168-77. Epub 2016 Jun 14. PMID:
27312419
Article Published Date
: Jul 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins isolated from blueberry ameliorates carbon tetrachloride induced liver fibrosis.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Oct ;120:491-499. Epub 2018 Jul 27. PMID:
30056145
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Anti-hepatitic activity of ginsenoside Ro.
Nov 30, 1991
Click here to read the entire abstract
Pubmed Data
: Planta Med. 1991 Dec ;57(6):523-6. PMID:
1818342
Article Published Date
: Nov 30, 1991
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Anti-inflammatory, anti-apoptotic, and antioxidant actions of Middle Eastern Phoenix dactylifera extract on mercury-induced hepatotoxicity in vivo.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2020 Aug ;47(8):6053-6065. Epub 2020 Jul 31. PMID:
32737827
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Chemically-Induced Liver Damage
,
Mercury Poisoning
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Mercury
[+]
Antibiotics induced elevations of plasma bile acids in rats.
Jan 19, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Sci. 2017 Jan 20. Epub 2017 Jan 20. PMID:
28108666
Article Published Date
: Jan 19, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Antibiotic Toxicity
,
Liver Damage: Drug-Induced
Problem Substances
:
Antibiotics
[+]
Antihepatotoxic benefits of Poria cocos polysaccharides on acetaminophen-lesioned livers in vivo and in vitro.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2019 May ;120(5):7482-7488. Epub 2018 Oct 30. PMID:
30378160
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Poria cocos
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Antioxidant and hepato-preventive effect of Citrus aurantium extract against carbon tetrachloride-induced hepatotoxicity.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Arch Physiol Biochem. 2019 Oct ;125(4):332-343. Epub 2018 Apr 17. PMID:
29663826
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Orange
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Antioxidant and hepatoprotective effects of Orthosiphon stamineus Benth. standardized extract.
Dec 31, 2006
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2007 ;35(1):115-26. PMID:
17265556
Article Published Date
: Dec 31, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Orthosiphon
Diseases
:
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Antioxidant and hepatoprotective potential of Lawsonia inermis L. leaves against 2-acetylaminofluorene induced hepatic damage.
Jan 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Jan 18 ;17(1):56. Epub 2017 Jan 18. PMID:
28100199
Article Published Date
: Jan 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Henna
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
antioxidant effect of thymoquinone could protect damage of liver parameters against morphine toxicity.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Prev Med. 2018 ;9:8. Epub 2018 Jan 29. PMID:
29441185
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Morphine
[+]
Antioxidant traits and protective impact of Moringa oleifera leaf extract against diclofenac sodium-induced liver toxicity in rats.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Feb ;43(2):e12704. Epub 2018 Oct 28. PMID:
31353658
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Diclofenac
[+]
Antioxidant, anti-inflammatory and anti-fibrotic effects of Boswellia serrate gum resin in CCl4-induced hepatotoxicity
Jan 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2020 Feb ;19(2):1313-1321. Epub 2019 Dec 19. PMID:
32010304
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin alleviated acetaminophen-induced hepatotoxicity in low protein-fed rats.
Feb 10, 2020
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2020 Feb 11:e22472. Epub 2020 Feb 11. PMID:
32048452
Article Published Date
: Feb 10, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Apigenin prevents acetaminophen-induced liver injury by activating the SIRT1 pathway.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:514. Epub 2020 Apr 24. PMID:
32425778
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Autophagy Up-regulation
,
Hepatoprotective
,
SIRT1 Activator
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Apigenin significantly increases the enzyme antioxidant defence mechanisms in paracetamol-induced hepatotoxicity.
Mar 01, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Drug Metab Pharmacokinet. 2017 Mar 2. Epub 2017 Mar 2. PMID:
28255865
Article Published Date
: Mar 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Apocynin prevented inflammation and oxidative stress in carbon tetra chloride induced hepatic dysfunction in rats.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Aug ;92:421-428. Epub 2017 May 27. PMID:
28558355
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apocynin
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Apple cider vinegar could be promising for attenuation of liver cell damages induced by several toxins through its powerful antioxidant properties.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Microsc Ultrastruct. 2020 Jul-Sep;8(3):126-131. Epub 2020 Sep 10. PMID:
33282688
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Apple Cider Vinegar
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Mercury
[+]
Apple polyphenols exert protective effects against Con A-induced immunological liver injury.
Aug 23, 2016
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2016 Aug 24. Epub 2016 Aug 24. PMID:
27567545
Article Published Date
: Aug 23, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interferon Gamma Reducer
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Concanavalin A
[+]
Apricot (Prunus armeniaca L.) has a protective effect against fatty liver and damage induced by carbon tetrachloride in Wistar rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Dec;102(12):1767-75. PMID:
19822030
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Apricot
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Apricot supplementation and irradiation given in combination, offer maximum protection against DMBA-induced hepatic carcinogenesis.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Aug ;70:128-33. Epub 2014 May 10. PMID:
24819963
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apricot
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy and Radiation Toxicity
,
Liver Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anticarcinogenic Agents
,
NF-kappaB Inhibitor
[+]
Aqueous extracts of C. papaya may be useful in preventing carbon tetrachloride and acetaminophen induced liver toxicities.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Intercult Ethnopharmacol. 2016 Jan-Feb;5(1):27-35. Epub 2016 Jan 27. PMID:
27069723
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Papaya
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Aqueous extracts of leaves of R. sativus offer partial protection against hepatotoxicity induced by carbon tetrachloride.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Afr J Tradit Complement Altern Med. 2014 ;11(3):102-6. Epub 2014 Apr 3. PMID:
25371570
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Radish
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Aqueous extracts of Rosa damascene may prevent hepatic damage from acetaminophen induced toxicity in rats.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Environ Pathol Toxicol Oncol. 2012 ;31(3):193-201. PMID:
23339694
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Rose
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Arctium lappa root extract prevents lead-induced liver injury.
Nov 23, 2019
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Antioxidants (Basel). 2019 Nov 24 ;8(12). Epub 2019 Nov 24. PMID:
31771282
Article Published Date
: Nov 23, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Burdock
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Lead
[+]
Artemisia turanica could have a protective role in diabetes-induced complications.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Pharmacopuncture. 2019 Jun ;22(2):109-114. Epub 2019 Jun 30. PMID:
31338251
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Mugwort
Diseases
:
Diabetic Complications
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Artichoke extract ameliorates carbon tetrachloride-induced liver damage and oxidative stress in rats.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2008 Sep;60(6):475-80. Epub 2008 Jun 25. PMID:
18583118
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
[+]
Artichoke leaf extract has liver protective effects and causes downregulation of oxidative stress in acute diazinon-induced liver injury.
Aug 29, 2019
Click here to read the entire abstract
Pubmed Data
: J Basic Clin Physiol Pharmacol. 2019 Aug 30 ;30(5). Epub 2019 Aug 30. PMID:
31469651
Article Published Date
: Aug 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide-Induced Toxicity: Organophosphates
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Organophosphate Pesticides
[+]
Artichoke leaf extract may be used as a pharmaceutical phytomedicine in the treatment of liver diseases.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Springerplus. 2016 ;5:216. Epub 2016 Feb 29. PMID:
27026910
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Artificial sweeteners cause cytoplasmic fatty change of varying degrees.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Coll Physicians Surg Pak. 2019 Sep ;29(9):848-851. PMID:
31455480
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
Problem Substances
:
Aspartame
,
Sucralose (aka Splenda)
[+]
Assessment of hepatoprotective effect of chokeberry juice in tats treated chronically with carbon tetrachloride.
Mar 10, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Molecules. 2020 Mar 11 ;25(6). Epub 2020 Mar 11. PMID:
32168847
Article Published Date
: Mar 10, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Association between serum CK-18 levels and the degree of liver damage in fructose-induced metabolic syndrome.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Syndr Relat Disord. 2018 Sep ;16(7):350-357. Epub 2018 Jul 10. PMID:
29989845
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
High Fructose Diet
,
Liver Damage
,
Metabolic Diseases
[+]
Astaxanthin alleviated aflatoxin B1-induced liver damage.
Jul 02, 2019
Click here to read the entire abstract
Pubmed Data
: J Vet Med Sci. 2019 Jul 3. Epub 2019 Jul 3. PMID:
31270307
Article Published Date
: Jul 02, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Aflatoxicosis
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Astaxanthin from haematococcus pluvialis ameliorates the chemotherapeutic drug doxorubicin induced liver injury.
May 13, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 May 14. Epub 2020 May 14. PMID:
32405635
Article Published Date
: May 13, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Nrf2 activation
[+]
Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2010 Feb ;696(1):69-80. Epub 2009 Dec 28. PMID:
20038455
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
DNA damage
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Chemopreventive
,
Tumor Suppressor Protein p53 Upregulation
[+]
Astaxanthin provided protection for the liver against acetaminophen hepatotoxicity.
Jan 29, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Jan 30 ;45:26-33. Epub 2017 Jan 30. PMID:
28152447
Article Published Date
: Jan 29, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Atorvastatin may contribute to hepatopathy through suppressing oxidized and reduce coenzyme q10 and mitochondrial function in the liver.
Apr 20, 2012
Click here to read the entire abstract
Pubmed Data
: Physiol Res. 2012 Apr 20 ;61(2):185-93. Epub 2012 Jan 31. PMID:
22292717
Article Published Date
: Apr 20, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Liver Damage: Drug-Induced
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Augmentation of hepatoprotective potential of Aegle marmelos in combination with piperine.
Aug 19, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chem Cent J. 2018 Aug 20 ;12(1):94. Epub 2018 Aug 20. PMID:
30123925
Article Published Date
: Aug 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bael
,
Piperine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Natural Substance Synergy
[+]
B. trimera a potential candidate drug capable of protecting the liver against damage caused by Acetaminophen overdose.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2014 ;2014:196598. Epub 2014 Nov 12. PMID:
25435714
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Baccharis trimera
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Bacopa monnieri may provide a beneficial herbal remedy for the efficient management of opioid related hepatotoxicity and nephrotoxicity.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2016 Feb ;2(2):e00068. Epub 2016 Feb 15. PMID:
27441247
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Kidney Damage: Drug-Induced
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Morphine
[+]
Baicalein attenuates acute liver injury by blocking NLRP3 inflammasome.
Nov 29, 2020
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2020 Nov 30. Epub 2020 Nov 30. PMID:
33272570
Article Published Date
: Nov 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
Diseases
:
Inflammation
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Banana peel polyphenols exert a good preventive effect against hepatic injury.
Apr 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2016 May ;11(5):1947-1954. Epub 2016 Mar 11. PMID:
27168833
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Banana Peel
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Malondialdehyde Down-regulation
[+]
Barley sprouts have a protective effect against alcohol-induced liver injury.
Jul 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID:
27455313
Article Published Date
: Jul 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Barley
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Bees' honey attenuation of metanil-yellow-induced hepatotoxicity in rats.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2013 ;2013:614580. Epub 2013 Jun 3. PMID:
23818929
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Metanil-Yellow Dye
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Beeswax contains long-chain alcohols which have a preventive effect against chemically-induced liver damage in mice.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2007 Jun;10(2):379-83. PMID:
17651079
Article Published Date
: Jun 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Beeswax
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Beetroot juice prevents adverse changes associated with chemically-induced mammary cancer promotion.
Feb 28, 2013
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2013 Mar 1. Epub 2013 Mar 1. PMID:
23450834
Article Published Date
: Feb 28, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Chemopreventive
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Beetroot juice protects against N-nitrosodiethylamine-induced liver injury in rats.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2012 Jun ;50(6):2027-33. Epub 2012 Mar 24. PMID:
22465004
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
,
DNA damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
N-nitrosodiethylamine
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Beetroot protects the liver against chemical toxicity.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2006 Feb;77(2):91-3. Epub 2005 Dec 20. PMID:
16376022
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Beetroot water extract could be used following silver nano particles as a potential therapeutic intervention to minimize liver toxicity.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2020 ;15:3471-3482. Epub 2020 May 15. PMID:
32547008
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Silver
[+]
Berbamine ameliorates ethanol-induced liver injury by inhibition of hepatic inflammation.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Chin J Nat Med. 2020 Mar ;18(3):186-195. PMID:
32245588
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Berbamine
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Berberine exerts a protective action against carbon tetrachloride induced acute liver injury.
Aug 05, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Aug 6. Epub 2019 Aug 6. PMID:
31432116
Article Published Date
: Aug 05, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
[+]
Berberine exhibits notable preventive effects on acetaminophen induced hepatotoxicity.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Jul ;103:1319-1326. Epub 2018 May 7. PMID:
29864914
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Berberine protects against the hepatic damage induced by Paracetamol
Feb 01, 2000
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2000 Feb ;71(1):25-33. PMID:
11449466
Article Published Date
: Feb 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Paracetamol
[+]
Betaine supplementation attenuates hepatic injury mediated by cisplatin.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2019 Nov ;71(6):1025-1033. Epub 2019 Jun 6. PMID:
32002889
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Betaine
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Betanin exerted a potential anti-inflammatory and antioxidant effect against hepato-renal damage induced by paracetamol and diclofenac over consumption.
Nov 25, 2019
Click here to read the entire abstract
Pubmed Data
: Biomarkers. 2019 Nov 26:1-24. Epub 2019 Nov 26. PMID:
31766895
Article Published Date
: Nov 25, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Betanin
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Diclofenac
,
Paracetamol
[+]
Bile acid conjugate prevents Oxaliplatin chemotherapy-induced fatty liver.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer. 2010 Jan 1;116(1):251-5. PMID:
19890960
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bile salts
Diseases
:
Chemotherapy-Induced Liver Toxicity
,
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Oxaliplatin
,
Fatty Liver
[+]
Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Sep ;38:324-31. Epub 2016 Jun 23. PMID:
27344638
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bisphenol A causes liver damage and selectively alters the neurochemical coding of intrahepatic parasympathetic nerves in juvenile porcine models.
Dec 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Dec 15 ;18(12). Epub 2017 Dec 15. PMID:
29244763
Article Published Date
: Dec 14, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Prenatal Chemical Exposures
Problem Substances
:
Bisphenol A
[+]
Bisphenol A exposure induces cholesterol synthesis and hepatic steatosis.
Aug 26, 2019
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2019 Aug 27 ;133:110786. Epub 2019 Aug 27. PMID:
31470036
Article Published Date
: Aug 26, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Hepatic Steatosis
,
Prenatal Chemical Exposures
Additional Keywords
:
Increased Risk
Problem Substances
:
Bisphenol A
[+]
Bisphenol A induced oxidative stress, inflammatory response, apoptosis and mitochondrial dysfunction in mouse colons and livers.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2019 Sep ;117:109182. Epub 2019 Jul 1. PMID:
31387175
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Problem Substances
:
Bisphenol A
[+]
Bisphenol A promotes hepatic lipid deposition involving Kupffer cell M1 polarization in male mice.
May 11, 2017
Click here to read the entire abstract
Pubmed Data
: J Endocrinol. 2017 May 12. Epub 2017 May 12. PMID:
28500084
Article Published Date
: May 11, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Bisphenol F induces nonalcoholic fatty liver disease-like changes.
Dec 21, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Pollut. 2020 Dec 22 ;271:116304. Epub 2020 Dec 22. PMID:
33401208
Article Published Date
: Dec 21, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
Problem Substances
:
Bisphenol F
[+]
Bisphenol S-induced chronic inflammatory stress in liver.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Pollut. 2019 Mar ;246:963-971. Epub 2018 Dec 24. PMID:
31159146
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Inflammation
,
Liver Damage
,
Oxidative Stress
Problem Substances
:
Bisphenol S
[+]
Bitter apple fruit possess significant hepatoprotective and antioxidant activity.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2015 May ;28(3):951-7. PMID:
26004728
Article Published Date
: Apr 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Apple
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Paracetamol
[+]
Black garlic exhibited significant protective effects on carbon tetrachloride-induced acute hepatic injury.
Mar 19, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Mar 20 ;24(6). Epub 2019 Mar 20. PMID:
30897831
Article Published Date
: Mar 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Garlic
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Black tea extract has a protective effect on the levels of lipid peroxidation and antioxidant enzymes in liver of mice with pesticide-induced liver injury.
Jul 01, 2006
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Funct. 2006 Jul-Aug;24(4):327-32. PMID:
15991261
Article Published Date
: Jul 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Blockage of CCL5 may promote liver regeneration.
Sep 03, 2019
Click here to read the entire abstract
Pubmed Data
: Cell Mol Immunol. 2019 Sep 3. Epub 2019 Sep 3. PMID:
31481754
Article Published Date
: Sep 03, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Liver Damage
,
Liver Damage: Drug-Induced
,
Liver Disease
[+]
Blueberries have preventive effect on carbon tetrachloride-induced hepatic fibrosis.
Aug 19, 2018
Click here to read the entire abstract
Pubmed Data
: Zhonghua Gan Zang Bing Za Zhi. 2018 Aug 20 ;26(8):590-595. PMID:
30317790
Article Published Date
: Aug 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Blueberry components could regulate histone acetylation and improve liver pathologic changes in rats with carbon tetrachloride-induced disease.
Feb 15, 2017
Click here to read the entire abstract
Pubmed Data
: Genet Mol Res. 2017 Feb 16 ;16(1). Epub 2017 Feb 16. PMID:
28218781
Article Published Date
: Feb 15, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Disease
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Blueberry prevents chemically-induced hepatic fibrosis in rats.
Jun 07, 2010
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2010 Jun 7;16(21):2657-63. PMID:
20518088
Article Published Date
: Jun 07, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
[+]
Both Nigella sativa and date reduce the toxic effects of aflatoxin-B1 in liver and kidney.
Jun 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Health Sci (Qassim). 2008 Jul ;2(2):26-44. PMID:
21475486
Article Published Date
: Jun 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Dates
,
Nigella sativa (aka Black Seed)
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Aflatoxin
[+]
Boysenberry anthocyanins is a food component available to prevent liver injury.
Dec 31, 2003
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2004 ;21(1-4):259-61. PMID:
15630207
Article Published Date
: Dec 31, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Berries: All
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Phytotherapy
[+]
BPA has a significant impact on the liver miRNome and transcriptome in adult zebrafish.
Oct 12, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Genes (Basel). 2017 Oct 13 ;8(10). Epub 2017 Oct 13. PMID:
29027980
Article Published Date
: Oct 12, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Liver Cancer
Additional Keywords
:
Risk Factors
Problem Substances
:
Bisphenol A
[+]
BPA induced liver fibrosis, which is related to the stimulation of the inflammatory response.
Dec 06, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Exp Pathol. 2016 Dec 7. Epub 2016 Dec 7. PMID:
27925325
Article Published Date
: Dec 06, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
,
Liver Fibrosis
,
Oxidative Stress
Problem Substances
:
Bisphenol A
[+]
Brazilian green propolis suppresses acetaminophen-induced hepatocellular necrosis.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Toxicol Pathol. 2018 Oct ;31(4):275-282. Epub 2018 Jul 1. PMID:
30393431
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Brazillian
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Brewer's yeast (S. cerevisiae) has a protective effect against chemically-induced liver damage in rats.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2009 Jun;28(3):338-45. Epub 2009 Feb 23. PMID:
19233522
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Yeast
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Broccoli sprout extract protected the liver from various types of xenobiotic substances through induction of detoxification enzymes and glutathione synthesis.
Sep 20, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2015 Sep 21 ;21(35):10091-103. PMID:
26401074
Article Published Date
: Sep 20, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli Sprouts
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Phase I Detoxification Enzyme Inducer
,
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Gene Expression Regulation
,
Plant Extracts
Problem Substances
:
Acetaminophen
[+]
Bromelain ameliorates hepatic microcirculation after warm ischemia indicating it may have liver protective effects after injury.
May 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2007 May 1;139(1):88-96. Epub 2007 Feb 8. PMID:
17292418
Article Published Date
: May 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Bromelain
Diseases
:
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Butterbur extract improves lipid profiles and antioxidant activities in monosodium L-glutamate-challenged mice.
Sep 30, 2010
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2010 Oct ;13(5):1216-23. PMID:
20828319
Article Published Date
: Sep 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Butterbur
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Monosodium Glutamate (MSG)
[+]
Butylated hydroxytoluene (BHT) exhibits liver toxicity in rats.
Apr 01, 1999
Click here to read the entire abstract
Pubmed Data
: Histol Histopathol. 1999 Apr;14(2):391-406. PMID:
10212800
Article Published Date
: Apr 01, 1999
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Butylated Hydroxytoluene (BHT)
[+]
Butylated hydroxytoluene (BHT) potentiates vitamin A induced liver damage in rats.
Aug 01, 1987
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 1987 Aug;90(1):1-9. PMID:
3629584
Article Published Date
: Aug 01, 1987
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Additional Keywords
:
Drug-Plant-Vitamin Synergies
Problem Substances
:
Butylated Hydroxytoluene (BHT)
[+]
C. longa administration decreased HSC activation and ameliorated hepatotoxic changes caused by cadmium in adult rats.
Jan 20, 2016
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2016 Jan 21:1-12. Epub 2016 Jan 21. PMID:
26796199
Article Published Date
: Jan 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Turmeric
Diseases
:
Cadmium Poisoning
,
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Caffeic acid phenethyl ester should be considered in the prevention of oxidative stress in diabetic liver.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Bratisl Lek Listy. 2016 ;117(5):276-82. PMID:
27215964
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Diabetic Complications
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Camel milk either alone or in combination with bee honey ameliorated the toxic effects of carbon tetrachloride.
May 29, 2016
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2016 May 30:1-10. Epub 2016 May 30. PMID:
27455095
Article Published Date
: May 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Camel Milk
,
Honey
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol exhibits therapeutic potential against ischemia/reperfusion liver injury in rats.
Nov 16, 2011
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2011 Nov 16 ;670(1):216-23. Epub 2011 Sep 14. PMID:
21930120
Article Published Date
: Nov 16, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Liver Damage
,
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Hepatoprotective
[+]
Carnosic acid attenuates arsenic-induced hepatotoxicity.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:1421438. Epub 2018 May 2. PMID:
29854073
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Arsenic
[+]
Carob honey has high antioxidant content, antioxidant property, and protective effect against carbon tetrachloride induced kidney and liver toxicity.
Oct 16, 2018
Click here to read the entire abstract
Pubmed Data
: Arch Med Res. 2018 Oct 17. Epub 2018 Oct 17. PMID:
30342848
Article Published Date
: Oct 16, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Renoprotective
[+]
Carrot extract protects the liver from chemical injury.
Jul 07, 1995
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 1995 Jul 7;47(2):69-74. PMID:
7500638
Article Published Date
: Jul 07, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Carrot
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Carthamus red may serve as a candidate with strong a hepatoprotective effect and antioxidant activity in liver damage.
Jul 08, 2013
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2013 Jul 9 ;148(2):570-8. Epub 2013 May 14. PMID:
23684718
Article Published Date
: Jul 08, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Safflower
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Additional Keywords
:
Plant Extracts
[+]
Carvacrol normalizes elevated liver enzymes induced by d-galactosamine-induced hepatotoxicity in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Fundam Clin Pharmacol. 2009 Dec;23(6):757-65. Epub 2009 Jul 24. PMID:
19650854
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
,
Gamma-glutamyl transpeptidase: Elevated
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Carvacrol suppresses the progression of liver fibrosis.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2019 Feb ;41(1):163-171. Epub 2019 Feb 1. PMID:
30706740
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Celery extract protects against pesticide-induced toxicity.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2011 Nov 1. Epub 2011 Nov 1. PMID:
22045891
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Celery
,
Flavonoids
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide-Induced Toxicity: Organophosphates
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Dichlorvos
,
Organophosphates
,
Pesticides
Adverse Pharmacological Actions
:
Hepatotoxic
,
Oxidant
[+]
Celosia cristata extract prevented oxidative stress-induced liver injury by enhancing hepatocyte antioxidant abilities.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2015 Feb 1 ;168:572-9. Epub 2014 Jul 31. PMID:
25172750
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Celosia cristata (cockscomb)
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Centella asiantica has a protective effect against acute liver injury in mice.
Feb 17, 2010
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2010 Feb 17. Epub 2010 Feb 17. PMID:
20171071
Article Published Date
: Feb 17, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Centella asiatica
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Centella asiatica may be useful in preventing liver damage.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Nov ;14(5):4521-4528. Epub 2016 Oct 5. PMID:
27748812
Article Published Date
: Oct 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-10 downregulation
,
Interleukin-12 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Chemical characteristics, antioxidant capacities and hepatoprotection of polysaccharides from pomegranate peel.
Dec 14, 2018
Click here to read the entire abstract
Pubmed Data
: Carbohydr Polym. 2018 Dec 15 ;202:461-469. Epub 2018 Sep 7. PMID:
30287023
Article Published Date
: Dec 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Polysaccharides
[+]
Chickpea extract exhibits a significant hepatoprotective effect against carbon tetrachloride induced liver injury in rats.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:344. Epub 2016 Sep 28. PMID:
27733831
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Chickpea
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Chicory ameliorates nitrosamine precusor induced oxidative stress and liver injury.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2163-9. Epub 2010 May 15. PMID:
20478349
Article Published Date
: Aug 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Chicory
Diseases
:
Chemically-Induced Liver Damage
,
Nitrosamnine-induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Chinese cabbage powder effectively reduced the incidence of liver tumour induced by aflatoxin B1 from 6.67% to 0% in animals.
Oct 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Chem. 2015 Nov 1 ;186:13-9. Epub 2015 Mar 6. PMID:
25976785
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cabbage
Diseases
:
Liver Cancer: Prevention
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Anticarcinogenic Agents
Additional Keywords
:
Risk Reduction
[+]
Chlorella has hepatoprotective properties against tetrachloride-induced oxidative damage in rats.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: In Vivo. 2009 Sep-Oct;23(5):747-54. PMID:
19779110
Article Published Date
: Sep 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Chlorella vulgaris ameliorates sodium nitrite-induced hepatotoxicity.
Nov 04, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2020 Nov 5. Epub 2020 Nov 5. PMID:
33151487
Article Published Date
: Nov 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Chlorella vulgaris extract ameliorates carbon tetrachloride-induced acute hepatic injury in mice.
Jul 07, 2011
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2011 Jul 7. Epub 2011 Jul 7. PMID:
21741806
Article Published Date
: Jul 07, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage
Pharmacological Actions
:
Glutathione Upregulation
,
Hepatoprotective
[+]
Chlorogenic acid could be a potential therapeutic to minimize sodium arsenite-induced hepatic injury.
Jan 31, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2020 Feb ;47(2):1161-1171. Epub 2019 Dec 9. PMID:
31820315
Article Published Date
: Jan 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
Problem Substances
:
Arsenic
[+]
Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Redox Biol. 2017 Feb 1 ;11:701-707. Epub 2017 Feb 1. PMID:
28187322
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Aspartame
[+]
Chronic inhalation of e-cigarette vapor may lead to increased inflammation, organ damage, and cardiorenal and hepatic disease.
Jan 30, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Regul Integr Comp Physiol. 2018 Jan 31. Epub 2018 Jan 31. PMID:
29384700
Article Published Date
: Jan 30, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
Problem Substances
:
Electronic Cigarettes
[+]
Chrysanthemum indicum might be an alternative and promising agent for the treatment of aging and age-associated brain and liver diseases
Jan 01, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 Jan 2. Epub 2019 Jan 2. PMID:
30610932
Article Published Date
: Jan 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Aging: Brain
,
Brain Inflammation
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Chrysin has a beneficial impact on oxidative and inflammation damage in the liver of aged male rats.
Jul 16, 2020
Click here to read the entire abstract
Pubmed Data
: Endocr Metab Immune Disord Drug Targets. 2020 Jul 17. Epub 2020 Jul 17. PMID:
32679027
Article Published Date
: Jul 16, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Aging: Liver
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Chrysin has a positive influence on hepatic marker enzymes in chemically-induced liver toxicity in rats.
Mar 31, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Mar 31. Epub 2010 Mar 31. PMID:
20362027
Article Published Date
: Mar 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
,
Gamma-glutamyl transpeptidase: Elevated
,
GGT
,
Results for Liver Enzymes: Elevated AST
Pharmacological Actions
:
Hepatoprotective
[+]
Chrysin prevents the necrosis and injury of acute acetaminophen-induced hepatotoxicity.
Nov 17, 2019
Click here to read the entire abstract
Pubmed Data
: Chem Res Toxicol. 2019 Nov 18 ;32(11):2329-2337. Epub 2019 Nov 1. PMID:
31625388
Article Published Date
: Nov 17, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Cissus quadrangularis protects gainst isoniazid-induced liver damage in rats.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Indian J Pharmacol. 2010 Dec;42(6):397-400. PMID:
21189914
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cissus quadrangularis
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Toxicity
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Citrus maxima peel powder produced significant hepatoprotective action in carbon tetrachloride administered rats.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:598179. Epub 2015 May 28. PMID:
26106435
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Citrus Peel
Diseases
:
Chemically-Induced Liver Damage
,
Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Citrus reticulata peel extract ameliorates hepatic steatosis, oxidative stress and inflammation.
May 21, 2020
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2020 May 22 ;83:108426. Epub 2020 May 22. PMID:
32559586
Article Published Date
: May 21, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Citrus Peel
,
Orange: Mandarin
Diseases
:
Hepatic Steatosis
,
Inflammation
,
Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Nrf2 activation
[+]
Cloudy apple juice potentiates hepatoprotection during experimental liver injury.
Aug 20, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Aug 21 ;140:1006-1017. Epub 2019 Aug 21. PMID:
31445146
Article Published Date
: Aug 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apple
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
[+]
Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice.
Jun 24, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2018 Jun 25 ;18(1):195. Epub 2018 Jun 25. PMID:
29940935
Article Published Date
: Jun 24, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Coconut Water
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Coenzyme-Q10 exerts hepatoprotective effect in fructose-induced fatty liver model.
Mar 09, 2020
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2020 Mar 10. Epub 2020 Mar 10. PMID:
32157594
Article Published Date
: Mar 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
,
High Fructose Diet
Pharmacological Actions
:
Hepatoprotective
[+]
Colocasia esculenta possesses hepatoprotective activity against thioacetamide in rats.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2015 Nov ;28(6 Suppl):2237-41. PMID:
26687753
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Taro
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Combination of pomegranate extract and curcumin ameliorates thioacetamide-induced liver fibrosis.
Jul 26, 2020
Click here to read the entire abstract
Pubmed Data
: Toxicol Mech Methods. 2020 Jul 27:1-23. Epub 2020 Jul 27. PMID:
32718261
Article Published Date
: Jul 26, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Pomegranate
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Combinatorial usage of fungal polysaccharides from Cordyceps sinensis and Ganoderma atrum ameliorate drug-induced liver injury in mice.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Sep ;119:66-72. Epub 2018 May 16. PMID:
29753871
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps sinensis
,
Medicinal Mushrooms
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Polysaccharides
[+]
Comparative hepatoprotective effect of Nigella sativa pre- and post-treatment.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2019 Jan ;32(1):205-212. PMID:
30772810
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Prophylactic Agents
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Comparison of ameliorative effects of Taraxacum syriacum and N-acetylcysteine against acetaminophen-induced oxidative stress in the liver and kidney.
Sep 23, 2020
Click here to read the entire abstract
Pubmed Data
: J Biochem. 2020 Sep 24. Epub 2020 Sep 24. PMID:
32970799
Article Published Date
: Sep 23, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
,
NAC (N-acetyl-L-cysteine)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Kidney Damage: Drug-Induced
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Renoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Constituents of L. fulvotomentosa and L. macranthoide are effective in decreasing carbon tetrachloride and D-Galactosamine-induced liver injuries.
May 31, 1999
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 1999 Jun ;24(6):363-4, 384. PMID:
12212032
Article Published Date
: May 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Honeysuckle
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Cordyceps exhibits potent hepatoprotective properties in an animal model.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2010 Jan;81(1):1-7. Epub 2009 Jul 8. PMID:
19596425
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps sinensis
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Coriandrum sativum has a protective effect on carbon tetrachloride-induced hepatotoxicity in mice.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2009 Apr;47(4):702-8. Epub 2008 Dec 29. PMID:
19146910
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Coriandrum sativum
Diseases
:
Chemotherapy-Induced Liver Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Cow urine distillate attenuates chemically-induced liver damage in rats.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Biomed Environ Sci. 2009 Aug;22(4):345-7. PMID:
19950531
Article Published Date
: Aug 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Urine
,
Urine: Cow
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
[+]
Cranberry extract exhibits promising hepatoprotective potential against the chemical induced hepatotoxicity.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Med. 2017 Nov ;10(11):1054-1058. Epub 2017 Oct 27. PMID:
29203101
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cranberry
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Funct. 2015 Jun ;33(4):202-10. Epub 2015 May 11. PMID:
25962994
Article Published Date
: May 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cranberry
,
Flavonoids
Diseases
:
Lipid Peroxidation
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Crocetin improves dengue virus-induced liver injury.
Jul 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Viruses. 2020 Jul 30 ;12(8). Epub 2020 Jul 30. PMID:
32751420
Article Published Date
: Jul 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocetin
Diseases
:
Dengue
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Crocin administration could protect the liver damage induced by morphine.
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Res Pharm Sci. 2016 Mar-Apr;11(2):120-9. PMID:
27168751
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Morphine
[+]
Crocin attenuates CCl 4-induced liver fibrosis via PPAR-γ mediated modulation of inflammation and fibrogenesis in rats.
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2020 Dec ;39(12):1639-1649. Epub 2020 Jul 7. PMID:
32633567
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Crocin has protective activities against ethanol toxic effects in the liver and kidney.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2020 Jan ;23(1):51-62. PMID:
32405348
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
,
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Crocus sativus could effectively alleviate methotrexate-induced hepatotoxicity.
Oct 25, 2019
Click here to read the entire abstract
Pubmed Data
: J Complement Integr Med. 2019 Oct 26. Epub 2019 Oct 26. PMID:
31675349
Article Published Date
: Oct 25, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Saffron
Diseases
:
Drug-Induced Toxicity: Methotrexate
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Crocus sativus extract containing polyphenols modulates oxidative stress and inflammatory response against anti-tuberculosis drugs-induced liver injury.
Jan 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Plants (Basel). 2020 Jan 30 ;9(2). Epub 2020 Jan 30. PMID:
32019201
Article Published Date
: Jan 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Saffron
Diseases
:
Liver Damage: Drug-Induced
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Crocus sativus hydroalcoholic extract has beneficial effects on inflammatory and enzymatic indices resulting from alcohol use in kidney and liver.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inflamm Res. 2019 ;12:269-283. Epub 2019 Oct 8. PMID:
31632125
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Saffron
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Cucurbitacin B could significantly suppress releases of inflammatory cytokines and improve liver fibrosis induced by concanavalin A.
May 24, 2020
Click here to read the entire abstract
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2020 May 25. Epub 2020 May 25. PMID:
32452080
Article Published Date
: May 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Liver Damage: Drug-Induced
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
,
Transforming growth factor beta (TGF-β) inhibitor
Problem Substances
: