Neural Tube Defects

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5 Substances Researched for Neural Tube Defects

Name	AC	CK
Folic Acid	1	10
Curcumin	1	2
EGCG (Epigallocatechin gallate)	1	2
Melatonin	1	2
Punicalagin	1	2

1 Problem Substances Researched for Neural Tube Defects

Name	AC	CK	Focus
Caffeine	1	10

Research Articles 7
Cumulative Knowledge Score 11
Overall Research Rating GOOD

View the Evidence:
7 Abstracts with Neural Tube Defects Research

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Association between maternal exposure to ambient PM10 and neural tube defects.Jan 23, 2020

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Pubmed Data : Int J Hyg Environ Health. 2020 Jan 24 ;225:113453. Epub 2020 Jan 24. PMID: 31986338

Article Published Date : Jan 23, 2020

Study Type : Human Study

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Diseases : Air Pollution Linked Toxicity, Neural Tube Defects

Additional Keywords : Increased Risk

[+]

Maternal caffeine consumption has been linked to neural tube defects.Nov 01, 2009

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Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2009 Nov;85(11):879-89. PMID: 19711421

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Diseases : Neural Tube Defects, Prenatal Nutrition: Health of the Offspring, Spina Bifida

Problem Substances : Caffeine

Adverse Pharmacological Actions : Teratogenic

[+]

This is the first study to show that folic acid prevents the entire spectrum of neural tube defects types.Jan 30, 2022

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Pubmed Data : Birth Defects Res. 2022 Jan 31. Epub 2022 Jan 31. PMID: 35098705

Article Published Date : Jan 30, 2022

Study Type : Human Study

Additional Links

Substances : Folic Acid

Diseases : Neural Tube Defects

Additional Keywords : Risk Reduction

[+]

Curcumin reduces high glucose induced neural tube defects by blocking cellular stress and caspase activation.May 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Am J Obstet Gynecol. 2015 Jun ;212(6):802.e1-8. Epub 2015 Jan 13. PMID: 25595578

Article Published Date : May 31, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Diabetes: Oxidative Stress, Diabetic Complications, Neural Tube Defects

Pharmacological Actions : Anti-Apoptotic, Antioxidants

[+]

EGCG could mitigate the teratogenic effects of hyperglycemia on the developing embryo and prevent diabetes-induced neural tube defects.Mar 11, 2016

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Pubmed Data : Am J Obstet Gynecol. 2016 Mar 12. Epub 2016 Mar 12. PMID: 26979632

Article Published Date : Mar 11, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Gestational Diabetes, Hyperglycemia, Neural Tube Defects

Additional Keywords : Hypomethylation, Methylation Downregulation, Risk Reduction

[+]

Melatonin supplementation may play an important role in the prevention of neural malformations in diabetic pregnancy.Oct 06, 2015

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Pubmed Data : J Pineal Res. 2015 Oct 7. Epub 2015 Oct 7. PMID: 26475080

Article Published Date : Oct 06, 2015

Study Type : Animal Study

Additional Links

Substances : Melatonin

Diseases : Neural Tube Defects

Additional Keywords : Risk Reduction

[+]

Punicalagin supplements could mitigate the teratogenic effects of hyperglycemia in the developing embryo.Nov 12, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biochem Biophys Res Commun. 2015 Nov 13 ;467(2):179-84. Epub 2015 Oct 13. PMID: 26453010

Article Published Date : Nov 12, 2015

Study Type : Animal Study

Additional Links

Substances : Punicalagin

Diseases : Diabetic Complications, Hyperglycemia, Lipid Peroxidation, Neural Tube Defects, Oxidative Stress

Pharmacological Actions : Antioxidants, Hypoglycemic Agents

Additional Keywords : Risk Reduction

Research Articles 7
Cumulative Knowledge Score 11
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 7 Abstracts with Neural Tube Defects Research

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Currently Available Sorting Options

Association between maternal exposure to ambient PM10 and neural tube defects.Jan 23, 2020

Click here to read the entire abstract

Maternal caffeine consumption has been linked to neural tube defects.Nov 01, 2009

Click here to read the entire abstract

This is the first study to show that folic acid prevents the entire spectrum of neural tube defects types.Jan 30, 2022

Click here to read the entire abstract

Curcumin reduces high glucose induced neural tube defects by blocking cellular stress and caspase activation.May 31, 2015

Click here to read the entire abstract

EGCG could mitigate the teratogenic effects of hyperglycemia on the developing embryo and prevent diabetes-induced neural tube defects.Mar 11, 2016

Click here to read the entire abstract

Melatonin supplementation may play an important role in the prevention of neural malformations in diabetic pregnancy.Oct 06, 2015

Click here to read the entire abstract

Punicalagin supplements could mitigate the teratogenic effects of hyperglycemia in the developing embryo.Nov 12, 2015

Click here to read the entire abstract

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Neural Tube Defects

View the Evidence:
7 Abstracts with Neural Tube Defects Research