Pubmed Data : Br J Nutr. 2018 Apr ;119(8):847-858. PMID: 29644950
Article Published Date : Mar 31, 2018
Study Type : Meta Analysis
Additional Links
Substances : Vitamin C
Diseases : Hip Fracture, Osteoporosis
Additional Keywords : Risk Reduction
Osteoporosis
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View the Evidence:
428 Abstracts with Osteoporosis Research
Greater dietary vitamin C intake was associated with a lower risk of hip fracture and osteoporosis Add to My Research
High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women. Add to My Research
Pubmed Data : Nutr Res. 2009 Apr;29(4):221-8. PMID: 19410972
Article Published Date : Apr 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K, Vitamin K2
Long-term use of warfarin was associated with osteoporotic fractures, at least in men with atrial fibrillation. Add to My Research
Pubmed Data : Arch Intern Med. 2006 Jan 23;166(2):241-6. PMID: 16432096
Article Published Date : Jan 23, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Drug-Induced Toxicity , Osteoporosis
Problem Substances : Warfarin
Low serum level of magnesium seems to be a risk factor for osteoporosis among the postmenopausal women. Add to My Research
Pubmed Data : Biol Trace Elem Res. 2014 Jun ;159(1-3):8-14. Epub 2014 Apr 12. PMID: 24728877
Article Published Date : May 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Magnesium
Diseases : Magnesium Deficiency, Osteoporosis
Additional Keywords : Risk Factors
Puerarin showed upregulating effects on bone mass in ovariectomy-induced postmenopausal osteoporosis. Add to My Research
Pubmed Data : Curr Stem Cell Res Ther. 2019 Jul 3. Epub 2019 Jul 3. PMID: 31269886
Article Published Date : Jul 02, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Puerarin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : Crit Rev Food Sci Nutr. 2019 Jul 10:1-15. Epub 2019 Jul 10. PMID: 31290343
Article Published Date : Jul 09, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Isoflavones
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Tai chi is effective in improving balance of older adults and in the absence of other interventions, reduces falls in the nonfrail elderly. Add to My Research
Pubmed Data : Altern Ther Health Med. 2011 Jan-Feb;17(1):40-8. PMID: 21614943
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Therapeutic Actions : Tai Chi
Additional Keywords : Risk Reduction
There was an association between the increase of at least one serving of fruits and vegetables per day and decreases in the risk of fractures. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(5):e0217223. Epub 2019 May 31. PMID: 31150426
Article Published Date : Dec 31, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Fractures: Bone, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
This present systematic review indicated that acupuncture could be an effective therapy for treating osteoporosis. Add to My Research
Pubmed Data : Am J Chin Med. 2018 ;46(3):489-513. Epub 2018 Apr 4. PMID: 29614884
Article Published Date : Dec 31, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Acupuncture
Pharmacological Actions : Osteoprotective
Pubmed Data : Clin Calcium. 2009 Dec;19(12):1805-14. PMID: 19949272
Article Published Date : Dec 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K2
Diseases : Bone Fractures, Osteoporosis
A black cohosh extract is equipotent to conjugated estrogens in reducing menopausal symptoms and bone markers, without adverse effects. Add to My Research
Pubmed Data : Maturitas. 2003 Mar 14;44 Suppl 1:S67-77. PMID: 12609561
Article Published Date : Mar 14, 2003
Study Type : Human Study
Additional Links
Substances : Black Cohosh
Diseases : Menopausal Syndrome, Osteoporosis
Additional Keywords : Superiority of Natural Substances versus Drugs
A specific exercise program targeting osteoporosis improves the condition of postmenopausal women with low bone density. Add to My Research
Pubmed Data : 1: Clin Ter. 2009 Mar-Apr;160(2):105-9. PMID:19452097
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Exercise
Pubmed Data : Aliment Pharmacol Ther. 2000 Nov;14(11):1451-7. PMID: 11069316
Article Published Date : Nov 01, 2000
Study Type : Human Study
Additional Links
Problem Substances : Alendronate (trade name Fosamax) , Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Gastrotoxic, Ulcerogenic
Pubmed Data : J Orthop Trauma. 2008 May-Jun;22(5):346-50. PMID: 18448990
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Alendronate (trade name Fosamax)
Although hip bone mineral density is strongly related to hip fracture risk in elderly white women, other clinical risk factors also are independent predictors of long-term risk. Add to My Research
Pubmed Data : J Am Geriatr Soc. 2004 Sep;52(9):1479-86. PMID: 15341549
Article Published Date : Sep 01, 2004
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Diabetes Mellitus: Type 2, Hip Fracture, Osteoporosis, Parkinson's Disease, Vision Loss
Additional Keywords : Diseases that are Linked
Ambient air pollution was associated with lower bone mineral content in a young adult population in a peri-urban area of South India. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JAMA Netw Open. 2020 Jan 3 ;3(1):e1918504. Epub 2020 Jan 3. PMID: 31899531
Article Published Date : Jan 02, 2020
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Osteoporosis
Additional Keywords : Increased Risk
Arimidex therapy contributes in the decline of bone mineral density in early breast cancer patients. Add to My Research
Pubmed Data : Bratisl Lek Listy. 2010;111(1):27-32. PMID: 20429308
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Additional Keywords : Drug: Tamoxifen
Artemisia princeps as a promising therapeutic option for the improvement of postmenopausal osteoporosis. Add to My Research
Pubmed Data : J Nutr Health Aging. 2016 ;20(5):533-9. PMID: 27102792
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Japanese mugwort
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Beer drinking contributes to higher bone density as a result of the phytoestrogen content (hops) of this alcoholic beverage. Add to My Research
Pubmed Data : Nutrition. 2009 Oct;25(10):1057-63. Epub 2009 Jun 13. PMID: 19527924
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Bisphosphonate use in chronic kidney disease is associated wtih adynamic bone disease. Add to My Research
Pubmed Data : Blood Purif. 2010;29(3):293-9. Epub 2010 Jan 21. PMID: 20090316
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Additional Keywords : Diseases that are Linked
Problem Substances : Bisphosphonates
Bisphosphonates used for osteoporosis in patients with cystic fibrosis increases bone mineral density without increasing bone quality/strength, while causing bone pain and flu-like symptoms. Add to My Research
Pubmed Data : Cochrane Database Syst Rev. 2009(4):CD002010. Epub 2009 Oct 7. PMID: 19821288
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Cystic Fibrosis, Osteoporosis
Problem Substances : Bisphosphonates
Bone mineral density is a significant prognostic factor for postmenopausal Caucasian women with breast cancer. Low bone mineral density is associated with a lower local and distant rate of recurrence. Add to My Research
Pubmed Data : Breast J. 2013 Mar-Apr;19(2):168-72. Epub 2013 Feb 13. PMID: 23406171
Article Published Date : Mar 01, 2013
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
Calcium supplementation (without vitamin D) is associated with increased risk of bone fracture. Add to My Research
Pubmed Data : Osteoporos Int. 2008 Aug;19(8):1119-23. Epub 2008 Feb 20. PMID: 18286218
Article Published Date : Aug 01, 2008
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Osteoporosis
Pubmed Data : Am J Clin Nutr. 2007 Dec;86(6):1780-90. PMID: 18065599
Article Published Date : Dec 01, 2007
Study Type : Human Study
Additional Links
Substances : Calcium
Diseases : Hip Fracture, Osteoporosis
Pubmed Data : J Bone Miner Res. 2009 Jun;24(6):1086-94. PMID: 19138129
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Carotenoids, Lycopene
Diseases : Osteoporosis
Correcting Dysbiosis may help to correct malabsorption and resulting bone disease. Add to My Research
Pubmed Data : Dig Dis Sci. 2001 May;46(5):1077-82. PMID: 11341652.PMID:11341652
Article Published Date : May 01, 2001
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Osteoporosis
DHEA supplementation improved lower extremity strength and function in older, frail women involved in a gentle exercise program of chair aerobics or yoga. Add to My Research
Pubmed Data : Pharmacol Biochem Behav. 2008 Oct 25. [Epub ahead of print] PMID: 20863330
Article Published Date : Oct 25, 2008
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Elderly: Age Specific Diseases, Osteoporosis
Additional Keywords : Sex Hormone-Binding Globulin
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Oct 30 ;9(11). Epub 2017 Oct 30. PMID: 29084183
Article Published Date : Oct 29, 2017
Study Type : Human Study
Additional Links
Substances : Magnesium
Pharmacological Actions : Osteoprotective
Dietary vitamin K2 supplement improves bone status after lung and heart transplantation. Add to My Research
Pubmed Data : Transplantation. 2010 Feb 27;89(4):458-64. PMID: 20177349
Article Published Date : Feb 27, 2010
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: Menaquinone-7
Pubmed Data : Br J Nutr. 2011 May 31:1-8. Epub 2011 May 31. PMID: 21736808
Article Published Date : May 31, 2011
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteoporosis, Postmenopausal Disorders
Dried plum in its whole form is a promising and efficacious functional food therapy for preventing bone loss in postmenopausal women. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 May 14 ;9(5). Epub 2017 May 14. PMID: 28505102
Article Published Date : May 13, 2017
Study Type : Human Study
Pubmed Data : Altern Ther Health Med. 2010 Mar-Apr;16(2):12-4. PMID: 11860726
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteoporosis
Drinking up to 3 cups of tea per day was associated with a 30% reduction in the risk of hip fractures in women. Add to My Research
Article Published Date : Nov 01, 1995
Study Type : Human Study
Additional Links
Substances : Green Tea
Diseases : Osteoporosis
DXA-generated Z-scores and T-scores may differ substantially and significantly in young adults. Add to My Research
Pubmed Data : J Clin Densitom. 2007 Oct-Dec;10(4):351-8. Epub 2007 Jul 26. PMID: 17662630
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Additional Keywords : T-Score/Z-Score Mythology
Anti Therapeutic Actions : DXA Scans
Elderly women with high bone mineral density (BMD) have up to 2.7 times greater risk of breast cancer, especially advanced cancer, compared with women with low BMD. Add to My Research
Pubmed Data : J Natl Cancer Inst. 2001 Jun 20;93(12):930-6. PMID: 11416114
Article Published Date : Jun 20, 2001
Study Type : Human Study
Additional Links
Anti Therapeutic Actions : High Bone Density
Gamma-linolenic acid (GLA) and Eicosapentaenoic acid (EPA) have beneficial effects on bone in elderly patients. Add to My Research
Pubmed Data : Aging (Milano). 1998 Oct;10(5):385-94. PMID: 9932142
Article Published Date : Oct 01, 1998
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) , Gamma-Linoleic Acid (GLA)
Diseases : Osteoporosis
Genistein compares favorably to HRT in supporting bone health in early postmenopausal women. Add to My Research
Pubmed Data : J Bone Miner Res. 2002 Oct;17(10):1904-12. PMID: 12369794
Article Published Date : Oct 01, 2002
Study Type : Human Study
Additional Links
Substances : Genistein
Additional Keywords : HRT Alternatives, Natural Substances Versus Drugs
Genistein has a positive effect on bone metabolism in osteopenic postmenopausal women, without increasing endometrial thickness. Add to My Research
Pubmed Data : Ann Intern Med. 2007 Jun 19;146(12):839-47. PMID: 17577003
Article Published Date : Jun 19, 2007
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Osteoporosis
Genistein is safe and effective in improving bone density without adverse responses in breast density or endometrium thickness in osteopenic, postmenopausal women. Add to My Research
Pubmed Data : J Clin Endocrinol Metab. 2008 Dec;93(12):4787-96. Epub 2008 Sep 16. PMID: 18796517
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Osteopenia, Osteoporosis
Green and yellow vegetable consumption is effective for maintaining bone mass in young women. Add to My Research
Pubmed Data : 1: Tohoku J Exp Med. 2009;218(2):149-54. PMID:19478471
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Osteoporosis
Group exercise has a positive effect on postmenopausal osteoporosis and osteopenia. Add to My Research
Pubmed Data : Acta Orthop Traumatol Turc. 2009 Aug-Oct;43(4):343-50. PMID: 19809232
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Therapeutic Actions : Exercise
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2010 ;7:12. Epub 2010 Feb 22. PMID: 20175915
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Coffee
High prevalence of vitamin D deficiency and osteoporosis in patients with fragility fractures of hip. Add to My Research
Pubmed Data : J Clin Orthop Trauma. 2019 Nov-Dec;10(6):1097-1100. Epub 2019 Mar 21. PMID: 31708635
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis, Vitamin D Deficiency
Additional Keywords : Risk Factors
Higher bone density (upper 33%) is associated with a 2-fold increased risk of breast cancer. Add to My Research
Pubmed Data : Bone. 2003 Mar;32(3):211-6. PMID: 12667548
Article Published Date : Mar 01, 2003
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Additional Keywords : Diseases that are Linked
Anti Therapeutic Actions : High Bone Density
Pubmed Data : Maturitas. 2007 Mar 20;56(3):312-21. Epub 2006 Oct 17. PMID: 17049767
Article Published Date : Mar 20, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
Higher bone mineral density is associated with higher incidence of estrogen receptor positive breast cancer. Add to My Research
Pubmed Data : Maturitas. 2007 Jul 20;57(3):221-5. Epub 2007 Jan 19. PMID: 17240090
Article Published Date : Jul 20, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
Hop rho iso-alpha acids, berberine, vitamin D(3) and vitamin K (1) favorably impact biomarkers of bone turnover in postmenopausal women. Add to My Research
Pubmed Data : J Bone Miner Metab. 2009 Dec 19. Epub 2009 Dec 19. PMID: 20024591
Article Published Date : Dec 19, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Increase in lumbar spine and femoral neck bone mineral density is associated with a 2.1 fold and 1.5 fold respectively, higher risk of breast cancer. Add to My Research
Pubmed Data : Maturitas. 2000 Jul 31;36(1):27-34. PMID: 10989239
Article Published Date : Jul 31, 2000
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Additional Keywords : Breast
Anti Therapeutic Actions : High Bone Density
Intake of fermented soybean (natto) increases circulating vitamin K2 and osteocalcin (a marker for bone formation) in normal individuals. Add to My Research
Pubmed Data : J Bone Miner Metab. 2000;18(4):216-22. PMID: 10874601
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Secretagogue
Isoflavones attenuate bone loss and have a potentially protective effect on the lumbar spine in women Add to My Research
Pubmed Data : Am J Clin Nutr. 2004 Feb;79(2):326-33. PMID: 14749241
Article Published Date : Feb 01, 2004
Study Type : Human Study
Additional Links
Substances : Isoflavones, Red Clover
Diseases : Osteoporosis
Lactobacillus reuteri reduces bone loss in older women with low bone mineral density. Add to My Research
Pubmed Data : J Intern Med. 2018 Jun 21. Epub 2018 Jun 21. PMID: 29926979
Article Published Date : Jun 20, 2018
Study Type : Human Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Long term use of vitamin C supplements was associated with a higher BMD in the early postmenopausal years and among never users of oestrogen. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Epidemiol Community Health. 1997 Oct ;51(5):479-85. PMID: 9425455
Article Published Date : Oct 01, 1997
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Osteoporosis
Long-term proton pump inhibitor therapy is associated with an increased risk of hip fracture. Add to My Research
Pubmed Data : JAMA. 2006 Dec 27;296(24):2947-53. PMID: 17190895
Article Published Date : Dec 27, 2006
Study Type : Human Study
Additional Links
Problem Substances : Proton-Pump Inhibitors
Long-term proton pump inhibitors use is associated with risk of bone complications. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tunis Med. 2018 Mar ;96(3):193-197. PMID: 30325487
Article Published Date : Feb 28, 2018
Study Type : Human Study
Additional Links
Diseases : Bone Diseases, Osteoporosis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
Long-term ultra-high hydrostatic pressurized brown rice intake prevents bone mineral density decline in elderly Japanese individuals. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2019 ;65(Supplement):S88-S92. PMID: 31619654
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Brown Rice
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Pubmed Data : Drug Saf. 2009;32(9):775-85. PMID: 19670917
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Bisphosphonates
Pubmed Data : Scand J Clin Lab Invest. 1998 May ;58(3):225-8. PMID: 9670346
Article Published Date : May 01, 1998
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Hip Fracture, Osteoporosis
Magnesium deficiency may contribute to osteoporosis promotion associated with gluten-sensitive enteropathy. Add to My Research
Pubmed Data : Osteoporos Int. 1996;6(6):453-61. PMID: 9116391
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Substances : Magnesium
Additional Keywords : Diseases that are Linked
Magnesium may have beneficial effects in reducing bone loss associated with high bone turnover, such as age-related osteoporosis. Add to My Research
Pubmed Data : J Biol Chem. 2002 Dec 27;277(52):50341-7. Epub 2002 Oct 16. PMID: 9709941
Article Published Date : Dec 27, 2002
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Osteoporosis
Mammographic breast density is inversely associated with bone mineral density in the perimenopausal women. Add to My Research
Pubmed Data : Ann Epidemiol. 2007 Aug;17(8):575-83. Epub 2007 May 29. PMID: 17532645
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Additional Keywords : Diseases that are Linked
Anti Therapeutic Actions : High Bone Density
Menaquinone-7 (vitamin K2) supplementation increases osteocalcin carboxylation associated with improved bone quality. Add to My Research
Pubmed Data : Br J Nutr. 2009 Oct;102(8):1171-8. Epub 2009 May 19. PMID: 19450370
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Bone Fractures, Osteoporosis
MK-7 in addition to ordinary meals could improve osteocalcin γ-carboxylation status. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2015 ;61(6):471-80. PMID: 26875489
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Most of the increase in mortality following hip and pelvic fractures is due to underlying conditions and probably would not be affected by reductions in the incidence of these fractures. Add to My Research
Pubmed Data : Arch Intern Med. 1996 Jul 22;156(14):1521-5. PMID: 8687260
Article Published Date : Jul 22, 1996
Study Type : Human Study
Additional Links
Additional Keywords : Osteoporosis Myths
Multiple hyperbaric oxygen treatments has the possibility of contributing to recovery acceleration in patients with transient osteoporosis of the hip. Add to My Research
Pubmed Data : Undersea Hyperb Med. 2016 Nov-Dec;43(7):847-854. PMID: 28777523
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Hyperbaric Treatment
Natto, a rich source of vitamin K2, promotes bone formation in premenopausal women. Add to My Research
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2004 Apr;50(2):114-20. PMID: 15242015
Article Published Date : Apr 01, 2004
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Neuromuscular and visual impairments (as well as femoral-neck BMD) are significant and independent predictors of the risk of hip fracture in elderly women. Add to My Research
Pubmed Data : Lancet. 1996 Jul 20;348(9021):145-9. PMID: 8684153
Article Published Date : Jul 20, 1996
Study Type : Human Study
Additional Links
Additional Keywords : Osteoporosis Myths
one-year treatment with melatonin increased bone mineral density at femoral neck in a dose-dependent manner, while high dose melatonin increased vBMD in the spine. Add to My Research
Pubmed Data : J Pineal Res. 2015 Jun 3. Epub 2015 Jun 3. PMID: 26036434
Article Published Date : Jun 02, 2015
Study Type : Human Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Osteogenic
Additional Keywords : Dose Response, Significant Treatment Outcome
Oophorectomy adversely affect healthy postmenopausal women by accelerating loss of bone mineral density (BMD) and the rate of increase in carotid artery intima-media thickness (CIMT). Add to My Research
Pubmed Data : Fertil Steril. 2014 Apr ;101(4):1117-22. Epub 2014 Feb 14. PMID: 24530156
Article Published Date : Apr 01, 2014
Study Type : Human Study
Additional Links
Diseases : Atherosclerosis, Carotid Artery Narrowing, Intima Media Thickening , Osteoporosis, Osteoporosis: Age-Related
Additional Keywords : Ovariectomy-Induced Changes
Anti Therapeutic Actions : Oophorectomy (Ovariectomy)
Orthosilicic acid has therapeutic value in the treatment of osteopenia and osteoporosis. Add to My Research
Pubmed Data : BMC Musculoskelet Disord. 2008 Jun 11;9:85. PMID: 18547426
Article Published Date : Jun 11, 2008
Study Type : Human Study
Additional Links
Substances : Silica: Orthosilicic acid
Diseases : Osteopenia, Osteoporosis
Pubmed Data : Bone. 1999 Mar;24(3):249-55. PMID: 10071918
Article Published Date : Mar 01, 1999
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Celiac Disease, Osteoporosis
Additional Keywords : Diseases that are Linked
Patients with Gaucher disease living in England have a high frequency of vitamin D deficiency Add to My Research
Pubmed Data : Mol Genet Metab. 2009 Mar ;96(3):113-20. Epub 2009 Jan 14. PMID: 19147383
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin D
Additional Keywords : Bone Density, Lysosomal Storage Disorder
Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats. Add to My Research
Pubmed Data : J Bone Miner Metab. 2000;18(2):71-6. PMID: 10701161
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients. Add to My Research
Pubmed Data : Gastroenterology. 2010 Jul;139(1):93-101. Epub 2010 Mar 27. PMID: 20353792
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Problem Substances : Histamine Receptor Antagonists
Pubmed Data : Int J Rheum Dis. 2009 Jul;12(2):130-5. PMID: 20374330
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Warfarin
Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes. Add to My Research
Pubmed Data : Diabetes Obes Metab. 2010 Aug;12(8):716-21. PMID: 20590749
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Problem Substances : Rosiglitazone (trade name Avandia)
Pubmed Data : J Clin Gastroenterol. 2006 Nov-Dec;40(10):906-9. PMID: 17063109
Article Published Date : Nov 01, 2006
Study Type : Human Study
Additional Links
Diseases : Celiac Disease, Osteoporosis
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Leptin Down-Regulation
Problem Substances : Gluten
Soy food consumption may reduce the risk of fracture in postmenopausal women, particularly among those in the early years following menopause. Add to My Research
Pubmed Data : Arch Intern Med. 2005 Sep 12;165(16):1890-5. PMID: 16157834
Article Published Date : Sep 12, 2005
Study Type : Human Study
Additional Links
Substances : Soy
Diseases : Bone Fractures, Osteoporosis
Additional Keywords : Risk Reduction
Pubmed Data : Eur J Nutr. 2006 Sep;45(6):327-34. Epub 2006 Jun 8. PMID: 16763748
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Substances : Isoflavones, Soy
Diseases : Osteoporosis
Soy phytoestrogen has a positive effect on bone turnover indicators in menopausal women with osteopenia. Add to My Research
Pubmed Data : Hum Cell. 1999 Dec;12(4):189-96. PMID: 16255781
Article Published Date : Dec 01, 1999
Study Type : Human Study
Additional Links
Substances : phytoestrogens, Soy Protein
Pharmacological Actions : Insulin-Like Growth Factor Inhibition/Downregulation
Soy product consumption is inversely associated with the risk for hip fracture in men and women. Add to My Research
Pubmed Data : Am J Epidemiol. 2009 Oct 1;170(7):901-9. Epub 2009 Aug 31. PMID: 19720865
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Isoflavones, Soy
Diseases : Hip Fracture, Osteoporosis
Additional Keywords : Risk Reduction
Soymilk and progesterone are beneficial for bone health when taken separately, but may cause bone loss if consumed together. Add to My Research
Pubmed Data : Eur J Nutr. 2004 Aug;43(4):246-57. Epub 2004 Apr 14. PMID: 15309425
Article Published Date : Aug 01, 2004
Study Type : Human Study
Additional Links
Substances : Soy
Diseases : Osteoporosis
Additional Keywords : Adverse Interaction Between Natural Substances, Soy Milk
Strontium renalate is a safe and effective treatment for veterbral and hip osteoporosis. Add to My Research
Pubmed Data : Curr Osteoporos Rep. 2005 Mar;3(1):30-4. PMID: 16036099
Article Published Date : Mar 01, 2005
Study Type : Human Study
Additional Links
Substances : Strontium
Additional Keywords : Risk Reduction
Strontium renalate safely reduces the risk of fractures in elderly women with osteoporosis, Add to My Research
Pubmed Data : J Bone Miner Res. 2006 Jul;21(7):1113-20. PMID: 16813532
Article Published Date : Jul 01, 2006
Study Type : Human Study
Additional Links
Substances : Strontium
Diseases : Osteoporosis
Additional Keywords : Fracture Reduction
Sunlight exposure ameliorates osteoporosis and hypovitaminosis in Parkinson's disease. Add to My Research
Pubmed Data : Parkinsonism Relat Disord. 2011 Jan;17(1):22-6. Epub 2010 Nov 2. PMID: 21050796
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis, Vitamin D Deficiency
Therapeutic Actions : Sunlight exposure
Sunlight exposure ameliorates osteoporosis and vitamin D deficiency in hospitalized, elderly women with Alzheimer's disease. Add to My Research
Pubmed Data : J Bone Miner Res. 2005 Aug;20(8):1327-33. Epub 2005 Apr 4. PMID: 16007329
Article Published Date : Aug 01, 2005
Study Type : Human Study
Additional Links
Therapeutic Actions : Sunlight exposure
Sunlight exposure increases the bone mineral density of stroke patients who have vitamin-D deficient bones. Add to My Research
Pubmed Data : 1: Neurology. 2003 Aug 12;61(3):338-42. PMID:12913194
Article Published Date : Aug 12, 2003
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Sunlight exposure
T'ai chi improves muscle strength, bone mineral density, and fear of falling in women with osteoarthritis. Add to My Research
Pubmed Data : J Altern Complement Med. 2010 Mar;16(3):227-33. PMID: 20192907
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Diseases : Osteoarthritis, Osteoporosis
Therapeutic Actions : Tai Chi
Tai chi chun exercise is beneficial for retarding bone loss in weight-bearing bones in early postmenopausal women. Add to My Research
Pubmed Data : 1: Arch Phys Med Rehabil. 2004 May;85(5):717-22. PMID:15129394
Article Published Date : May 01, 2004
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Tai Chi
Tai Chi has a beneficial effect on bone formation and bone resorption in breast cancer survivors. Add to My Research
Tai Chi may contribute to maintaining bone mineral density and reducing fracture rate in postmenopausal women. Add to My Research
Pubmed Data : Arch Phys Med Rehabil. 2007 May;88(5):673-80. PMID: 17466739
Article Published Date : May 01, 2007
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Tai Chi
Tamoxifen usage is associated with bone loss in patients who continued to menstruate after adjuvant chemotherapy. Add to My Research
Pubmed Data : J Clin Oncol. 2006 Feb 1;24(4):675-80. PMID: 16446340
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Additional Keywords : Drug: Tamoxifen
Problem Substances : Tamoxifen
Pubmed Data : J Pediatr Endocrinol Metab. 1996 Mar;9 Suppl 1:101-11. PMID: 17921409
Article Published Date : Mar 01, 1996
Study Type : Human Study
Additional Links
The combination of β-cryptoxanthin and vitamin C is inversely associated with the risk of developing osteoporosis in post-menopausal Japanese female subjects. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2016 ;62(3):185-91. PMID: 27465725
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Cryptoxanthin, Vitamin C
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Factors
The consumption of vitamin K2 rich fermented soybean food products may contribute to the relatively lower fracture risk of Japanese women. Add to My Research
Pubmed Data : Nutrition. 2001 Apr;17(4):315-21. PMID: 11369171
Article Published Date : Apr 01, 2001
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Additional Keywords : Risk Reduction
The majority of those patients who will sustain a low-trauma fracture do not meet the T-score definition of osteoporosis. Conversely, younger individuals with BD in the osteoporotic range but no other risk factors have relatively low rates of fracture. Add to My Research
Pubmed Data : Curr Osteoporos Rep. 2012 Mar ;10(1):28-41. PMID: 22274642
Article Published Date : Mar 01, 2012
Study Type : Human Study
Additional Links
Additional Keywords : T-Score/Z-Score Mythology
The use of rosiglitazone (Avandia) in type 2 diabetic patients is associated with an increased risk of heart failure and of some fractures, mainly in women. Add to My Research
Pubmed Data : Lancet. 2009 Jun 20;373(9681):2125-35. Epub 2009 Jun 6. PMID: 19501900
Article Published Date : Jun 20, 2009
Study Type : Human Study
Additional Links
Additional Keywords : Drug: Metformin
Problem Substances : Rosiglitazone (trade name Avandia)
The Western-type diet results in mild acidosis and increased cortisol secretion which adversely effects bone metabolism. Add to My Research
Pubmed Data : Am J Physiol Renal Physiol. 2003 Jan;284(1):F32-40. Epub 2002 Sep 24. PMID: 12388390
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Therapeutic Actions : Dietary Modification: Less Acid/More Alkaline Foods
These result shows that pantothenic acid rich diet can protect bone loss from estrogen deficiency. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(8):5008-5018. Epub 2019 Aug 15. PMID: 31497217
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin B-5 (Pantothenic Acid)
Diseases : Bone Diseases, Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
These results confirm the ability of dried plum to prevent the loss of total body BMD in older osteopenic postmenopausal women. Add to My Research
Pubmed Data : Osteoporos Int. 2016 Feb 22. Epub 2016 Feb 22. PMID: 26902092
Article Published Date : Feb 21, 2016
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteopenia, Osteoporosis
Thirty-nine percent of Hologic (Hologic, Inc., Bedford, MA) subjects and 30% of Lunar (GE Lunar, GE Madison, WI) subjects diagnosed with "osteoporosis" by T-score were reclassified as either "normal" or "osteopenia" when their Z-score was used. Add to My Research
Pubmed Data : J Clin Densitom. 2009 Jan-Mar;12(1):11-6. PMID: 19195620
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Additional Keywords : T-Score/Z-Score Mythology
Anti Therapeutic Actions : DXA Scans
This study suggests that daily boron intake of 1 mg/L may affect bone metabolism in postmenopausal women positively. Add to My Research
Treatment with loop diuretics affects bone turnover and decreases bone mineral density. Add to My Research
Pubmed Data : J Bone Miner Res. 2006 Jan;21(1):163-70. Epub 2005 Oct 10. PMID: 16355285
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Treatment with proton pump inhibitors increases the rate of subsequent treatment with anti-osteoporotic drugs. Add to My Research
Pubmed Data : Pharmacoepidemiol Drug Saf. 2010 Jul;19(7):763-9. PMID: 20582909
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Diseases : Acid Reflux, Osteoporosis
Additional Keywords : Downward Spiral of Drug Treatment
Problem Substances : Bisphosphonates
Use of proton pump inhibitors for 7 or more years is associated with a significantly increased risk of an osteoporosis-related fracture. There is an increased risk of hip fracture after 5 or more years exposure. Add to My Research
Pubmed Data : CMAJ. 2008 Aug 12;179(4):319-26. PMID: 18695179
Article Published Date : Aug 12, 2008
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Usual dietary intake of fermented soybeans (Natto) is associated with bone mineral density in premenopausal women. Add to My Research
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2002 Jun;48(3):207-15. PMID: 12350079
Article Published Date : Jun 01, 2002
Study Type : Human Study
Additional Links
Substances : Natto
Diseases : Osteoporosis
Vitamin C supplement use appears to have a beneficial effect on levels of BMD, especially among postmenopausal women using concurrent estrogen therapy and calcium supplements. Add to My Research
Pubmed Data : J Bone Miner Res. 2001 Jan ;16(1):135-40. PMID: 11149477
Article Published Date : Jan 01, 2001
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Osteoporosis
Vitamin D insufficiency is a common risk factor for osteoporosis associated with increased bone remodelling and low bone mass. Add to My Research
Pubmed Data : J Midlife Health. 2016 Oct-Dec;7(4):163-168. PMID: 28096639
Article Published Date : Sep 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis, Vitamin D Deficiency
Additional Keywords : Risk Factors
Vitamin D3 and vitamin K2 have a therapeutic effect on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis. Add to My Research
Pubmed Data : J Nutr. 2008 May;138(5):954-63. PMID: 11180916
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Vitamin K2 (MK-4) may be beneficial in the maintenance of bone health in postmenopausal women. Add to My Research
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2009 Feb;55(1):15-21. PMID: 19352059
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: (MK-4)
Vitamin K2 had a positive effect on bone mineral density in osteoporotic adults with cerebral palsy. Add to My Research
Pubmed Data : Brain Dev. 2017 Jun 14. Epub 2017 Jun 14. PMID: 28624135
Article Published Date : Jun 13, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Cerebral Palsy, Osteoporosis
Vitamin K2 improves hip bone geometry and bone strength indices in postmenopausal women. Add to My Research
Pubmed Data : Osteoporos Int. 2007 Jul;18(7):963-72. Epub 2007 Feb 8. PMID: 17287908
Article Published Date : Jul 01, 2007
Study Type : Human Study
Additional Links
Substances : Vitamin K
Diseases : Osteoporosis
Vitamin K2 treatment in combination with calcium supplementation increases bone mineral density in the treatment of postmenopausal osteoporosis. Add to My Research
Pubmed Data : J Obstet Gynaecol Res. 2006 Apr;32(2):230-4. PMID: 16594930
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: (MK-4)
Diseases : Osteoporosis
vitamin Vitamin (2) works synergistically with alendronate on improving both osteocalcin carboxylation and BMD of femoral neck in postmenopausal women with osteoporosis. Add to My Research
Pubmed Data : J Bone Miner Metab. 2008;26(3):260-4. Epub 2008 May 11. PMID: 18470667
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Bone Fractures, Osteoporosis
Additional Keywords : Drug Synergy
Weight bearing yoga training has a positive effect on bone in postmenopausal women by slowing down bone resorption. Add to My Research
Pubmed Data : J Med Assoc Thai. 2009 Sep;92 Suppl5:S102-8. PMID: 19891384
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Women in the lowest quartile of bone mass appear to be protected against breast cancer. Add to My Research
Pubmed Data : Breast. 2001 Aug;10(4):313-7. PMID: 14965600
Article Published Date : Aug 01, 2001
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
Women with a positive family history of breast cancer and who are in the highest tertile bone mineral density are at a 3.41-fold increased risk compared with women in the lowest tertile. Add to My Research
Pubmed Data : Am J Epidemiol. 1998 Jul 1;148(1):22-9. PMID: 9663400
Article Published Date : Jul 01, 1998
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
Women with bone mineral density above the 25th percentile have 2.0 to 2.5 times increased risk of breast cancer compared with women below the 25th percentile. Add to My Research
Pubmed Data : JAMA. 1996 Nov 6;276(17):1404-8. PMID: 8892715
Article Published Date : Nov 06, 1996
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
Women with highest tertile bone mineral density (BMD) measured at the Ward's triangle and at the femoral neck are respectively at 2.2-and 3.3-fold increased risk of breast cancer compared with women at the lowest tertile of BMD. Add to My Research
Pubmed Data : Eur J Epidemiol. 2004;19(8):785-92. PMID: 15469036
Article Published Date : Jan 01, 2004
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Top Geriatr Rehabil. 2016 Apr ;32(2):81-87. Epub 2015 Nov 5. PMID: 27226695
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Yoga
Pharmacological Actions : Osteogenic, Osteoprotective
Yoga may be an alternative physical activity for the rehabilitation of osteoporotic subjects. Add to My Research
Pubmed Data : Eur J Phys Rehabil Med. 2010 Feb 18. Epub 2010 Feb 18. PMID: 20332729
Article Published Date : Feb 18, 2010
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Yoga
Onion juice consumption showed a positive modulatory effect on the bone loss and bone mineral density. Add to My Research
Pubmed Data : Food Funct. 2016 Feb 17 ;7(2):902-12. PMID: 26686359
Article Published Date : Feb 16, 2016
Study Type : Animal Study, Human In Vitro
The results of the present study suggested that vitamin K2 targets miR-133a to regulate osteogenesis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 May ;15(5):2473-2480. Epub 2017 Mar 9. PMID: 28447758
Article Published Date : Apr 30, 2017
Study Type : Human In Vitro
Additional Links
Substances : Vitamin K2
Diseases : Osteonecrosis, Osteoporosis
Pharmacological Actions : MicroRNA modulator, Osteogenic
Calcium, Vitamin D and a Gluten-Free diet decreased bone pain and improved muscle strength. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Osteoporos. 2011 Dec ;6(1-2):209-213. Epub 2011 Jun 15. PMID: 22207878
Article Published Date : Dec 01, 2011
Study Type : Human: Case Report
Additional Links
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free
Problem Substances : Gluten
High dose vitamin D may have a therapeutic role in certain cases of chronic pain associated with sickle cell anemia. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Case Rep Gastrointest Med. 2018 ;2018:4294805. Epub 2018 Apr 30. PMID: 29854491
Article Published Date : Dec 31, 2017
Study Type : Human: Case Report, Review
Additional Links
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
"Clove (Syzygium aromaticum Linn) extract rich in eugenol and eugenol derivatives shows bone-preserving efficacy." Add to My Research
18β-glycyrrhetinic acid is a promising novel candidate in the treatment of osteoclast-related diseases such as postmenopausal osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:647. Epub 2018 Jun 20. PMID: 29973878
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : 18β-Glycyrrhetinic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside can be considered as a potential therapeutic for the treatment of postmenopausal osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Aug 28 ;19(9). Epub 2018 Aug 28. PMID: 30154383
Article Published Date : Aug 27, 2018
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Chondroprotective, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
A mineral-rich extract from the red marine algae Lithothamnion calcareum preserves bone structure and function in female mice on a Western-style diet. Add to My Research
Pubmed Data : Calcif Tissue Int. 2010 Apr;86(4):313-24. Epub 2010 Feb 24. PMID: 20180099
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Red Marine Algae
Anti Therapeutic Actions : Western Diet
A soy extract may be more effective than purified genistein in improving tibial trabecular bone quality in ovariectomized mice. Add to My Research
Pubmed Data : 1: Mol Pharm. 2009 Jul-Aug;6(4):1152-9. PMID: 19793844
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Additional Keywords : Plant Extracts, The Whole is Superior to the Monochemical Part
A western-style diet reduces bone mass and biomechanical bone strength to a greater extent in male compared with female rats during development. Add to My Research
Pubmed Data : Br J Nutr. 2003 Sep;90(3):589-95. PMID: 13129465
Article Published Date : Sep 01, 2003
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Anti Therapeutic Actions : Western Diet
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2013 Apr ;3(2):134-8. PMID: 24716168
Article Published Date : Mar 31, 2013
Study Type : Animal Study
All these results strongly indicate that puerarin exerts its anti-osteoprotic action independently of the ER-mediated pathway. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2012 ;58(3):202-9. PMID: 22878391
Article Published Date : Dec 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Allicin reversed the process of frailty in aging male Fischer 344 rats with osteoporosis. Add to My Research
Pubmed Data : J Gerontol A Biol Sci Med Sci. 2019 Sep 21. Epub 2019 Sep 21. PMID: 31541608
Article Published Date : Sep 20, 2019
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Anabolic therapy with Equisetum arvense along with bone mineralising nutrients in ovariectomized rat model of osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2016 May-Jun;48(3):312-5. PMID: 27298503
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Horsetail
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Natural Substances Versus Drugs
Analysis of anti-osteoporosis function of chlorogenic acid by gene microarray profiling in ovariectomy rat model. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2018 08 31 ;38(4). Epub 2018 Aug 31. PMID: 30054432
Article Published Date : Jan 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Anti-climacterium effects of pomegranate concentrated solutions in ovariectomized ddY mice. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2017 Apr ;13(4):1249-1266. Epub 2017 Feb 8. PMID: 28413464
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Additional Keywords : Ovariectomy-Induced Changes, Risk Reduction
Anti-inflammatory and anti-osteoporotic potential of Lactobacillus plantarum A41 and L. fermentum SRK414 as probiotics. Add to My Research
Pubmed Data : Probiotics Antimicrob Proteins. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31372901
Article Published Date : Aug 01, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:2617868. Epub 2016 Apr 10. PMID: 27143981
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Antrodia camphorata
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : Bone Regeneration, Plant Extracts
Aqueous extracts of parsley, basil and chicory showed bone protection against glucocorticoid-induced osteoporosis in rats. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 ;16(1):165. Epub 2016 Jun 2. PMID: 27255519
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Bone Density Conservation Agents
Additional Keywords : Plant Extracts
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Dec 11 ;7(1):17332. Epub 2017 Dec 11. PMID: 29230013
Article Published Date : Dec 10, 2017
Study Type : Animal Study
Additional Links
Substances : Mugwort
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Ascorbic acid administration in the Akr1A1 knockout mice led to controllable osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Jan 31 ;8(5):7357-7369. PMID: 28060768
Article Published Date : Jan 30, 2017
Study Type : Transgenic Animal Study
Additional Links
Substances : Vitamin C
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Pubmed Data : Phytomedicine. 2007 Feb;14(2-3):136-42. Epub 2006 May 18. PMID: 16597369
Article Published Date : Feb 01, 2007
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Osteoporosis
Asiatic acid may be a potential anti-resorptive agent for postmenopausal osteoporosis. Add to My Research
Pubmed Data : Calcif Tissue Int. 2019 Aug 21. Epub 2019 Aug 21. PMID: 31435709
Article Published Date : Aug 20, 2019
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Osteoporosis, Postmenopausal Disorders
Pharmacological Actions : Osteoprotective
Beneficial effects of paeoniflorin on osteoporosis induced by high-carbohydrate, high-fat diet-associated hyperlipidemia. Add to My Research
Pubmed Data : Biochem Biophys Res Commun. 2018 04 15 ;498(4):981-987. Epub 2018 Mar 17. PMID: 29550473
Article Published Date : Jan 14, 2018
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Pharmacological Actions : Hypolipidemic, Osteoprotective
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bosn J Basic Med Sci. 2017 Oct 22. Epub 2017 Oct 22. PMID: 29055350
Article Published Date : Oct 21, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Osteoprotective
Pubmed Data : J Dent Res. 2018 Sep 10:22034518797275. Epub 2018 Sep 10. PMID: 30199654
Article Published Date : Sep 09, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
Berberine may be a potential treatment for controlling bone loss in diabetic osteoporosis. Add to My Research
Pubmed Data : Biomed Pharmacother. 2018 Sep 14 ;108:280-287. Epub 2018 Sep 14. PMID: 30223099
Article Published Date : Sep 13, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Pharmacological Actions : Antioxidants, Osteoprotective
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2016 Dec ;38(6):1661-1672. Epub 2016 Nov 2. PMID: 27840967
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Bergamot orange
Diseases : Diabetic Complications, Osteoporosis
Beta-caryophyllene may be used as a therapeutic agent for the prevention and treatment of osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Dec ;12(6):3602-3606. Epub 2016 Oct 18. PMID: 28105093
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Bisphosphonates do not improve bone material characteristics such as tissue strength, elastic modulus, and cortical toughness in an animal model of osteoporosis. Add to My Research
Pubmed Data : Bone. 2009 Nov 26. PMID: 19931661
Article Published Date : Nov 26, 2009
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Bisphosphonates
Black raspberry extracts may benefit osteoporotic patients with prostatic disease by simultaneously altering the activation of osteoblasts and osteoclasts. Add to My Research
Pubmed Data : Aging Male. 2015 Jun ;18(2):124-32. Epub 2014 Aug 19. PMID: 25136745
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Raspberry
Diseases : Aging, Osteoporosis
Additional Keywords : Cannabinoid Receptors, Plant Extracts
Black raspberry vinegar could be an effective natural alternative for the prevention of postmenopausal osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 ;21(2). Epub 2016 Jan 26. PMID: 26821009
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Raspberry
Diseases : Osteoporosis, Ovariectomy Associated Adverse Changes
Pharmacological Actions : Prophylactic Agents
Additional Keywords : Risk Reduction
Pubmed Data : Asia Pac J Clin Nutr. 2004;13(2):210-6. PMID: 15228990
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Black Tea
Diseases : Osteoporosis
Blueberry diets in early life prevent senescence of osteoblasts and bone loss in ovariectomized adult female rats. Add to My Research
Pubmed Data : PLoS One. 2011 ;6(9):e24486. Epub 2011 Sep 2. PMID: 21912699
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Blueberry
Diseases : Aging, Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
Boron stimulates bone formation, inhibits bone resorption, resulting in a therapeutic effect against osteoporosis. Add to My Research
Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2006 Dec;26(12):1785-8. PMID: 17259120
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Osteoporosis
Pubmed Data : Nutrition. 2006 May;22(5):559-63. Epub 2006 Feb 10. PMID: 16472977
Article Published Date : May 01, 2006
Study Type : Animal Study
Pubmed Data : Life Sci. 2016 Dec 1 ;166:20-26. Epub 2016 Sep 30. PMID: 27697446
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Consumption of vitamin D2 enhanced mushrooms is associated with improved bone health. Add to My Research
Pubmed Data : J Nutr Biochem. 2015 Jul ;26(7):696-703. Epub 2015 Mar 5. PMID: 25792284
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Mushrooms: All
Diseases : Osteoporosis
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
CoQ10 stimulates the proliferation and differentiation of BMSCs and is effective for the treatment of OVX induced osteoporosis. Add to My Research
Pubmed Data : Mol Med Rep. 2018 Jan ;17(1):400-407. Epub 2017 Oct 26. PMID: 29115467
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Pubmed Data : J Food Biochem. 2019 Jul ;43(7):e12895. Epub 2019 May 15. PMID: 31353703
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Metabolic Syndrome X, Osteoporosis
Pharmacological Actions : Osteoprotective
Pubmed Data : Exp Biol Med (Maywood). 2008 Sep 29. PMID: 18824723
Article Published Date : Sep 29, 2008
Study Type : Animal Study
Additional Links
Substances : Cumin
Diseases : Osteoporosis
Additional Keywords : Natural Substances Versus Drugs
Curcumin alleviated HLS-induced reduction of bone mineral density in tibiae and preserved bone structure in tibiae and mechanical strength in femurs. Add to My Research
Pubmed Data : Osteoporos Int. 2015 May 12. Epub 2015 May 12. PMID: 25963235
Article Published Date : May 11, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Vitamin D Receptor (VDR) Modulator
Additional Keywords : Microgravity Induced Bone Loss
Curcumin improves bone microarchitecture and enhances mineral density in transgenic mice. Add to My Research
Pubmed Data : Phytomedicine. 2011 Jan 15;18(2-3):205-13. Epub 2010 Jul 16. PMID: 20637579
Article Published Date : Jan 15, 2011
Study Type : Animal Study
Additional Links
Substances : Curcumin
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Curcumin may be a potential therapeutic agent for the treatment of glucocorticoid induced osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2015 Dec 11. Epub 2015 Dec 11. PMID: 26677102
Article Published Date : Dec 10, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Osteoporosis
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
Problem Substances : Dexamethasone
Curcumin may be a promising drug for prevention and treatment of glucocorticoid-induced osteoporosis. Add to My Research
Pubmed Data : Clin Exp Pharmacol Physiol. 2015 Oct 30. Epub 2015 Oct 30. PMID: 26515751
Article Published Date : Oct 29, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Osteoporosis
Curcumin produces beneficial changes in bone turnover and increases in bone strength using the ovariectomized mature rat model of postmenopausal osteoporosis. Add to My Research
DHA exerts an anti-osteoclastogenic effect by suppressing the proliferation and differentiation of bone marrow-derived macrophages. Add to My Research
Pubmed Data : Cell Signal. 2016 Nov 9 ;29:226-232. Epub 2016 Aug 9. PMID: 27836739
Article Published Date : Nov 08, 2016
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Osteoporosis, Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective
Pubmed Data : J Cell Physiol. 2008 Jan;214(1):201-9. PMID: 17929247
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Osteoporosis
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:423869. Epub 2015 Mar 22. PMID: 25874211
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : Biol Pharm Bull. 2004 Apr;27(4):583-6. PMID: 15056872
Article Published Date : Apr 01, 2004
Study Type : Animal Study
Additional Links
Substances : Dioscorea spongiosa
Diseases : Osteoporosis
Pubmed Data : Ir J Med Sci. 2016 Aug ;185(3):581-7. Epub 2015 Jun 19. PMID: 26089290
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Diosgenin protects against alveolar bone loss in ovariectomized rats via regulating long non-coding RNAs. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Nov ;16(5):3939-3950. Epub 2018 Sep 3. PMID: 30344672
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : MicroRNA modulator, Osteoprotective
Dried and free flowing granules of Spinacia oleracea accelerate bone regeneration and alleviate postmenopausal osteoporosis. Add to My Research
Pubmed Data : Menopause. 2017 06 ;24(6):686-698. PMID: 28118295
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Spinach
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Effects of Nigella sativa and human parathyroid hormone on bone mass and strength in diabetic rats. Add to My Research
Pubmed Data : Biol Trace Elem Res. 2007 Jun ;116(3):321-8. PMID: 17709912
Article Published Date : May 31, 2007
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
Pubmed Data : Calcif Tissue Int. 2012 Mar 21. Epub 2012 Mar 21. PMID: 22434366
Article Published Date : Mar 21, 2012
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
EGCG reversed GIO in rats by protecting osteoblasts by activating the Nrf2 signaling pathway. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:447. Epub 2018 May 9. PMID: 29867459
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Osteoporosis
Pubmed Data : Acupunct Med. 2012 Mar ;30(1):37-43. PMID: 22378584
Article Published Date : Mar 01, 2012
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis, Ovariectomy Associated Adverse Changes
Therapeutic Actions : Electroacupuncture
Additional Keywords : Ovariectomy-Induced Changes
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31934719
Article Published Date : Jan 13, 2020
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Inflammatory Bowel Diseases, Osteoporosis
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
Emodin suppresses the cadmium induced osteoporosis by inhibiting osteoclast formation. Add to My Research
Pubmed Data : Environ Toxicol Pharmacol. 2017 Sep ;54:162-168. Epub 2017 Jul 18. PMID: 28738286
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Cadmium Poisoning , Osteoporosis
Pharmacological Actions : Osteoprotective
Evaluation of anti-osteoporotic activity of butanolic fraction from Passiflora foetida in ovariectomy-induced bone loss in mice. Add to My Research
Pubmed Data : Biomed Pharmacother. 2017 Apr ;88:804-813. Epub 2017 Feb 1. PMID: 28160755
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Fennel supresses the ovariectomy-induced increase in bone turnover, indicating it may prevent postmenopausal osteoporosis. Add to My Research
Pubmed Data : Int J Mol Med. 2012 Jun ;29(6):1053-9. Epub 2012 Mar 23. PMID: 22447109
Article Published Date : Jun 01, 2012
Study Type : Animal Study
Additional Links
Substances : Fennel
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : Food Funct. 2018 May 23. Epub 2018 May 23. PMID: 29790498
Article Published Date : May 22, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Bone Diseases, Osteoporosis
Pubmed Data : Bone. 2015 Apr ;73:132-44. Epub 2014 Dec 29. PMID: 25554600
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Osteoporosis
Pharmacological Actions : Interleukin-6 Downregulation
Additional Keywords : Ovariectomy-Induced Changes
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2018 Apr ;41(4):2059-2069. Epub 2018 Jan 23. PMID: 29393365
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Genistein and equol positively effect bone quality and quantity in osteoporotic mice. Add to My Research
Pubmed Data : J Vet Med Sci. 2002 Mar;64(3):227-35. PMID: 20036112
Article Published Date : Mar 01, 2002
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Genistein is superior to the bone drugs alendronate, raloxifene and estradiol in osteoporotic, ovariectomized rats. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2008 Nov;155(6):896-905. Epub 2008 Aug 11. PMID: 18695641
Article Published Date : Nov 01, 2008
Study Type : Animal Study
Additional Links
Substances : Genistein
Additional Keywords : Ovariectomy-Induced Changes, Superiority of Natural Substances versus Drugs
Genistein preserved the biomechanical quality of the trabecular bone regardless of the microstructure and bone mineral density. Add to My Research
Pubmed Data : J Bone Miner Metab. 2008;26(4):342-9. Epub 2008 Jul 4. PMID: 18600400
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Grapefruit juice showed a beneficial anti-osteoporotic effect against prednisolone-induced osteoporosis. Add to My Research
Pubmed Data : Cytotechnology. 2019 May 30. Epub 2019 May 30. PMID: 31147813
Article Published Date : May 29, 2019
Study Type : Animal Study
Additional Links
Substances : Grapefruit
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Green tea polyphenols mitigate bone loss of female rats in a chronic inflammation-induced bone loss model. Add to My Research
Pubmed Data : J Nutr Biochem. 2009 Dec 3. Epub 2009 Dec 3. PMID: 19962296
Article Published Date : Dec 03, 2009
Study Type : Animal Study
Additional Links
Substances : Green Tea
Diseases : Osteoporosis, Osteoporosis: Inflammation Induced
Green tea polyphenols mitigate deterioration of bone microarchitecture in middle-aged female rats. Add to My Research
Pubmed Data : Bone. 2009 Apr;44(4):684-90. Epub 2008 Dec 11. PMID: 19118658
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants
Additional Keywords : Bone Quality
Harmine enhances type H vessel formation and prevents bone loss in ovariectomized mice. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2018 ;8(9):2435-2446. Epub 2018 Mar 28. PMID: 29721090
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Psychedelics:All
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Harmine inhibits osteoclast differentiation and bone resorption in vitro and in vivo. Add to My Research
Pubmed Data : Eur J Pharmacol. 2011 Jan 15 ;650(2-3):511-8. Epub 2010 Nov 1. PMID: 21047508
Article Published Date : Jan 14, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Psychedelics:All
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : J Ethnopharmacol. 2016 Feb 17 ;179:66-75. Epub 2015 Dec 19. PMID: 26712566
Article Published Date : Feb 16, 2016
Study Type : Animal Study
Additional Links
Substances : Devils Claw
Diseases : Osteoporosis
Pharmacological Actions : Bone Density Conservation Agents
Additional Keywords : Ovariectomy-Induced Changes
Hesperetin prevents bone resorption by inhibiting RANKL-induced osteoclastogenesis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1028. Epub 2018 Sep 11. PMID: 30254586
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Hesperidin could be considered to be a beneficial treatment for preventing diabetic osteoporosis in growing age. Add to My Research
Pubmed Data : Exp Toxicol Pathol. 2017 Jan 26. Epub 2017 Jan 26. PMID: 28132802
Article Published Date : Jan 25, 2017
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Diabetes Mellitus: Type 1, Osteoporosis
Pharmacological Actions : Osteoprotective , Prophylactic Agents
Additional Keywords : Risk Reduction
Hesperidin has therapeutic effects in the formation and maintenance of bone mass and strength. Add to My Research
Pubmed Data : J Appl Physiol. 2008 Mar;104(3):648-54. Epub 2008 Jan 3. PMID: 18174393
Article Published Date : Mar 01, 2008
Study Type : Animal Study
High-dose diosgenin reduces bone loss in ovariectomized rats via attenuation of the RANKL/OPG ratio. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2014 Sep 25 ;15(9):17130-47. Epub 2014 Sep 25. PMID: 25257532
Article Published Date : Sep 24, 2014
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Hu Zhang (resveratrol) has positive effect on bone loss in the ovariectomized rat model. Add to My Research
Pubmed Data : J Med Food. 2005 Spring;8(1):14-9. PMID: 15857203
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Substances : Hu Zhang (Polygonum cuspidatum), Resveratrol
Diseases : Osteoporosis
Humulus lupulus L. extract may protect against bone loss, and have potentials in the treatment of osteoporosis. Add to My Research
Pubmed Data : Chin J Integr Med. 2019 Mar 27. Epub 2019 Mar 27. PMID: 30919241
Article Published Date : Mar 26, 2019
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Inhibition of osteoclastogenesis and bone resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 Dec 1 ;5:17605. Epub 2015 Dec 1. PMID: 26620037
Article Published Date : Nov 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Pubmed Data : Eur J Pharmacol. 2019 Dec 15 ;865:172785. Epub 2019 Nov 9. PMID: 31712059
Article Published Date : Dec 14, 2019
Study Type : Animal Study
Additional Links
Substances : Isoquercitrin
Diseases : Osteoporosis
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor, Osteoprotective
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Dec ;20(6):5197-5207. Epub 2019 Oct 16. PMID: 31638215
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Kefir has a protective effect against bone loss, deterioration of trabecular microarchitecture, and biomechanical dysfunction. Add to My Research
Pubmed Data : Osteoporos Int. 2015 Feb ;26(2):589-99. Epub 2014 Oct 3. PMID: 25278298
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Kefir, Milk: Fermented
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic
Additional Keywords : Significant Treatment Outcome
Kudzu completely prevents ovariectomized bone loss in mice, indicating it may be an alternative to hormone replacement therapy in the prevention of osteoporosis in postmenopausal women. Add to My Research
Pubmed Data : J Bone Miner Metab. 2003;21(5):268-75. PMID: 12928827
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Kudzu
Diseases : Osteoporosis
L-arginine supplementation normalizes bone turnover and preserves bone mass in streptozotocin-induced diabetic rats. Add to My Research
Lactobacillus plantarum NK3 and Bifidobacterium longum NK49 may simultaneously alleviate bacterial vaginosis and osteoporosis. Add to My Research
Pubmed Data : J Med Food. 2019 Oct ;22(10):1022-1031. Epub 2019 Aug 5. PMID: 31381476
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Diseases : Bacterial Vaginosis, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
Pubmed Data : J Nutr. 2009 May;139(5):958-64. Epub 2009 Mar 25. PMID: 19321577
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Lactoferrin
Diseases : Osteoporosis
Long-term dietary intake of chia seed is associated with increased bone mineral content and improved hepatic and intestinal morphology. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jul 19 ;10(7). Epub 2018 Jul 19. PMID: 30029467
Article Published Date : Jul 18, 2018
Study Type : Animal Study
Additional Links
Substances : Chia
Diseases : Osteoporosis
Long-term electroacupuncture stimulation prevents osteoporosis in ovariectomised osteopaenic rats. Add to My Research
Pubmed Data : Acupunct Med. 2018 Apr 6. Epub 2018 Apr 6. PMID: 29625972
Article Published Date : Apr 05, 2018
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Osteoprotective
Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Animal Model Exp Med. 2019 Mar ;2(1):51-57. Epub 2019 Feb 21. PMID: 31016287
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Laser Treatment: Low-Level
Additional Keywords : Ovariectomy-Induced Changes
Low‑molecular weight fucoidan inhibits the differentiation of osteoclasts and reduces osteoporosis in ovariectomized rats. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Feb ;15(2):890-898. Epub 2016 Dec 20. PMID: 28000877
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : Nutrition. 1993 Jan-Feb;9(1):71-2. PMID: 8467115
Article Published Date : Jan 01, 1993
Study Type : Animal Study
Additional Links
Substances : Lysine
Diseases : Osteoporosis
Maca protects against estrogen deficient bone loss in an animal model of ovariectomy induced osteoporosis. Add to My Research
Pubmed Data : J Ethnopharmacol. 2006 Apr 21;105(1-2):274-9. Epub 2006 Feb 8. PMID: 16466876
Article Published Date : Apr 21, 2006
Study Type : Animal Study
Additional Links
Substances : Maca
Diseases : Osteoporosis
magnolol is a promising agent for the treatment of osteoporosis and associated disorders. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2019 Feb 18. Epub 2019 Feb 18. PMID: 30816431
Article Published Date : Feb 17, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Magnolol
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Pubmed Data : Biol Trace Elem Res. 2008 Jul;124(1):28-34. Epub 2008 Mar 11. PMID: 18330520
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Manganese
Diseases : Osteoporosis
Melatonin restores the osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells. Add to My Research
Pubmed Data : Free Radic Biol Med. 2019 Oct 24. Epub 2019 Oct 24. PMID: 31669348
Article Published Date : Oct 23, 2019
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants
Additional Keywords : Mesenchymal Stem Cells
Melatonin treatment is an efficient and practical strategy to improve in vitro expansion of BMMSCs for tissue engineering and cytotherapy. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2016 ;6(11):1899-917. Epub 2016 Aug 8. PMID: 27570559
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Regenerative
Additional Keywords : Mesenchymal Stem Cells
Menaquinone-7, a form of vitamin K2, has a stimulatory effect on bone formation in the femoral tissues of elderly female rats in vitro. Add to My Research
Pubmed Data : Int J Mol Med. 2002 Dec;10(6):729-33. PMID: 12429999
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Pubmed Data : Biofactors. 2004;22(1-4):5-19. PMID: 15630245
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Aging, Osteoporosis
Montmorency tart cherry protects against age-related bone loss in female C57BL/6 mice. Add to My Research
Pubmed Data : Eur J Nutr. 2018 Oct 30. Epub 2018 Oct 30. PMID: 30377814
Article Published Date : Oct 29, 2018
Study Type : Animal Study
Additional Links
Substances : Tart Cherry
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Pubmed Data : Int J Med Mushrooms. 2016 ;18(7):559-69. PMID: 27649725
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : Plant Extracts
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway. Add to My Research
Pubmed Data : Life Sci. 2018 Jun 5. Epub 2018 Jun 5. PMID: 29883721
Article Published Date : Jun 04, 2018
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Myricetin may be a potential agent for the treatment of periodontitis and osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 Mar 22 ;17(3):422. Epub 2016 Mar 22. PMID: 27011174
Article Published Date : Mar 21, 2016
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Osteoporosis, Periodontitis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
N-acetylcysteine prevents orchiectomy-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(7):4337-4347. Epub 2019 Jul 15. PMID: 31396339
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Osteoprotective
Pubmed Data : Am J Chin Med. 2007;35(4):663-7. PMID: 17708632
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Osteoporosis
Pubmed Data : Chem Biol Interact. 2017 Jan 5 ;261:11-17. Epub 2016 Nov 8. PMID: 27833010
Article Published Date : Jan 04, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Bone Fractures, Osteoporosis
Pharmacological Actions : Angiogenesis Inducing Agents
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2014 ;14(1):22. Epub 2014 Jan 14. PMID: 24422662
Article Published Date : Jan 01, 2014
Study Type : Insect Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Additional Keywords : Ovariectomy-Induced Changes
Nigella sativa seed extract demonstrated incredibly positive effects on enhanced bone healing in this experimental osteoporotic model. Add to My Research
Pubmed Data : J Craniofac Surg. 2016 Aug 10. Epub 2016 Aug 10. PMID: 27513784
Article Published Date : Aug 10, 2016
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
Nobiletin clearly restored the alveolar bone mass in a mouse experimental model for periodontitis by inhibiting LPS-induced bone resorption. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2012 ;119(4):390-4. Epub 2012 Jul 31. PMID: 22850615
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Nobiletin , Tangeretin
Additional Keywords : Significant Treatment Outcome
Nobiletin-loaded micelles reduce ovariectomy-induced bone loss by suppressing osteoclastogenesis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2019 ;14:7839-7849. Epub 2019 Sep 26. PMID: 31576127
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Noni fruit puree compares favorably in analgesic and anti-inflammatory activity to tramadol and hydrocortisone, respectively, in an animal model of arthritis. Add to My Research
Pubmed Data : Phytother Res. 2009 Jun 22. PMID: 19548275
Article Published Date : Jun 22, 2009
Study Type : Animal Study
Additional Links
Substances : Noni
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents: Non-Steroidal
Additional Keywords : Natural Substances Versus Drugs
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:1039364. Epub 2018 Mar 25. PMID: 29765488
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cerebral Ischemia, Osteoporosis
Pharmacological Actions : Neuroprotective Agents, Osteoprotective
Oleanolic acid and ursolic acid improve bone properties and calcium nalance and modulate vitamin D metabolism in aged female rats. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1435. Epub 2018 Dec 4. PMID: 30564129
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid, Ursolic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Oleanolic acid exerts bone protective effects in ovariectomized mice by inhibiting osteoclastogenesis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2018 May ;137(1):76-85. Epub 2018 Apr 6. PMID: 29703642
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid
Diseases : Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
Oleuropein protects against bone loss associated with ovariectomy and inflammation. Add to My Research
Pubmed Data : Clin Nutr. 2006 Oct;25(5):859-68. Epub 2006 Jun 5. PMID: 16740345
Article Published Date : Oct 01, 2006
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Inflammation, Osteoporosis
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 May ;11(5):1881-1888. Epub 2016 Mar 10. PMID: 27168821
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Olive oil prevents bone loss in tumor patients and has excellent prospects for curing osteoporosis after menopause. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Interv Aging. 2014 ;9:2087-95. Epub 2014 Dec 2. PMID: 25506212
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Malondialdehyde Down-regulation
Olives prevent bone loss caused by ovariectomy and chemically induced inflammation in rats. Add to My Research
Pubmed Data : Bone. 2008 Jun;42(6):1154-63. Epub 2008 Feb 29. PMID: 18387868
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Onion
Diseases : Osteoporosis
Oral administration of kaempferol inhibits bone loss in rat model of ovariectomy-induced osteopenia. Add to My Research
Pubmed Data : Pharmacol Rep. 2017 Oct ;69(5):1113-1119. Epub 2017 May 13. PMID: 29031689
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : J Nat Med. 2016 Apr ;70(2):225-33. Epub 2016 Jan 27. PMID: 26815435
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pueraria mirifica
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
Paeonol inhibits RANKL-induced osteoclastogenesis by inhibiting ERK, p38 and NF-kappaB pathway. Add to My Research
Pubmed Data : Eur J Pharmacol. 2008 Jun 24 ;588(1):124-33. Epub 2008 Apr 16. PMID: 18495114
Article Published Date : Jun 23, 2008
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Osteoporosis
Pharmacological Actions : NF-kappaB Inhibitor, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Phellinus linteus extract protected against osteoporosis by balancing the number of osteoblasts and osteoclasts. Add to My Research
Pubmed Data : Int J Med Mushrooms. 2016 ;18(1):39-47. PMID: 27279443
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Phellinus Linteus
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Phloretin was effective in preventing estrogen deficiency-induced osteoclastogenic resorption. Add to My Research
Pubmed Data : Phytomedicine. 2014 Sep 15 ;21(10):1208-15. Epub 2014 Jun 2. PMID: 24932975
Article Published Date : Sep 14, 2014
Study Type : Animal Study
Additional Links
Substances : Phloretin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : Bone. 2006 Dec;39(6):1331-42. Epub 2006 Aug 4. PMID: 16890505
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Plum
Diseases : Osteoporosis
Pubmed Data : J Ethnopharmacol. 2011 Apr 28. Epub 2011 Apr 28. PMID: 21550389
Article Published Date : Apr 28, 2011
Study Type : Animal Study
Additional Links
Substances : Polygonatum Sibiricum
Additional Keywords : Ovariectomy-Induced Changes
Pomegranate improves depressive symptoms and bone properties in a menopausal syndrome model due to its estrogen content (estradiol, estrone and estriol). Add to My Research
Pubmed Data : J Ethnopharmacol. 2004 May;92(1):93-101. PMID: 15099854
Article Published Date : May 01, 2004
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
Pomegranate may be supportive in the preservation of bone density and the treatment of vaginal epithelial atrophy. Add to My Research
Pubmed Data : J Obstet Gynaecol Res. 2018 Mar 30. Epub 2018 Mar 30. PMID: 29603520
Article Published Date : Mar 29, 2018
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Osteoporosis, Vaginal Atrophy
Pharmacological Actions : Osteoprotective
Pubmed Data : J Nutr Health Aging. 2017 ;21(10):1299-1306. PMID: 29188893
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pomegranate Seed
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts, Plant Oils
Possible osteoprotective effects of myricetin in STZ induced diabetic osteoporosis in rats. Add to My Research
Pubmed Data : Eur J Pharmacol. 2019 Nov 19:172805. Epub 2019 Nov 19. PMID: 31756333
Article Published Date : Nov 18, 2019
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Osteoprotective
Prolonged use of bisphophonates may lead to excess mineralization, resulting in microcracks that interfere with bone quality/strength. Add to My Research
Pubmed Data : Joint Bone Spine. 2007 Jan;74(1):39-47. Epub 2006 Nov 28. PMID: 17196423
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:324. Epub 2017 May 31. PMID: 28620304
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Black Tea
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : Am J Chin Med. 2017 ;45(8):1725-1744. Epub 2017 Nov 9. PMID: 29121799
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Kudzu
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Endocrinol. 2016 Nov ;231(2):121-133. Epub 2016 Sep 6. PMID: 27601445
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pueraria mirifica
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
Pubmed Data : Eur J Pediatr. 2009 Dec;168(12):1541-2. Epub 2009 Mar 11. PMID: 18313241
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Pueraria mirifica
Diseases : Osteoporosis
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 May 1 ;115:108570. Epub 2019 May 1. PMID: 31054509
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Diabetic Complications, Osteoporosis
Puerarin and zinc additively prevent mandibular bone loss through inhibiting osteoclastogenesis in ovariectomized rats. Add to My Research
Pubmed Data : Histol Histopathol. 2017 Aug ;32(8):851-860. Epub 2016 Dec 14. PMID: 27966208
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Pubmed Data : Mol Med Rep. 2012 Jun ;5(6):1419-22. Epub 2012 Apr 2. PMID: 22470138
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Anti-Apoptotic, Osteoprotective
Pubmed Data : Curr Mol Med. 2018 Mar 9 ;17(7):488-496. PMID: 29256352
Article Published Date : Mar 08, 2018
Study Type : Animal Study, In Vitro Study
Pubmed Data : Phytother Res. 2012 Jan ;26(1):153-5. Epub 2011 Jun 28. PMID: 21710590
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis, Ovariectomy Associated Adverse Changes
Pharmacological Actions : Antioxidants
Rats fed with canned soft drinks had higher concentrations of Aluminum in blood, liver and bone than rats fed with glass bottled soft drinks. Add to My Research
Pubmed Data : Biometals. 1994 Jan ;7(1):57-60. PMID: 8118174
Article Published Date : Jan 01, 1994
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Aluminium Cans, Sugary soda
Red Yeast Rice significantly increases bone formation in the rabbit experimental model. Add to My Research
Pubmed Data : Chin Med. 2008 Mar 29;3:4. PMID: 18373874
Article Published Date : Mar 29, 2008
Study Type : Animal Study
Additional Links
Substances : Red Yeast Rice
Diseases : Osteoporosis
Pubmed Data : Neurology. 2007 Feb 20;68(8):563-8. PMID: 20458604
Article Published Date : Feb 20, 2007
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Osteoporosis
Rosiglitazone causes bone loss in mice by suppressing osteoblast (bone-building cells) differentiation and bone formation. Add to My Research
Pubmed Data : Endocrinology. 2005 Mar;146(3):1226-35. Epub 2004 Dec 9. PMID: 15591153
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Additional Keywords : Accelerated Aging
Problem Substances : Rosiglitazone (trade name Avandia)
Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone. Add to My Research
Pubmed Data : Endocrinology. 2007 Jun;148(6):2669-80. Epub 2007 Mar 1. PMID: 17332064
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Additional Keywords : Accelerated Aging
Problem Substances : Rosiglitazone (trade name Avandia)
Rosiglitazone may increase the risk of bone fracture by increasing osteoclast (bone-dissolving cells) generation. Add to My Research
Pubmed Data : Cell Metab. 2010 Jun 9;11(6):503-16. PMID: 20519122
Article Published Date : Jun 09, 2010
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis, Osteoporosis: Over-active Osteoclasts
Problem Substances : Rosiglitazone (trade name Avandia)
Pubmed Data : Bull Exp Biol Med. 2008 Jan;145(1):75-7. PMID: 17031045
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Osteoporosis
Pubmed Data : J Nutr. 2007 Jul;137(7):1769-75. PMID: 16951718
Article Published Date : Jul 01, 2007
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Bone Fractures, Osteoporosis
Rubus coreanus (Blackberry) has bone-protecting effect in overiectomized rats, without undesirable effects on the uterus and other solid organs. Add to My Research
Pubmed Data : Menopause. 2008 Jul-Aug;15(4 Pt 1):676-83. PMID: 18709701
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Blackberry
Diseases : Osteoporosis
Safflower bud inhibits RANKL-induced osteoclast differentiation and prevents bone loss in ovariectomized mice. Add to My Research
Pubmed Data : Phytomedicine. 2017 Oct 15 ;34:6-13. Epub 2017 Jul 4. PMID: 28899511
Article Published Date : Oct 14, 2017
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
Pubmed Data : Calcif Tissue Int. 2002 Jul;71(1):88-94. Epub 2002 Jun 20. PMID: 12073158
Article Published Date : Jul 01, 2002
Study Type : Animal Study
Additional Links
Substances : Safflower
Diseases : Osteoporosis
Sesamin promotes osteoblastic differentiation and protects rats from osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2019 Jul 17 ;25:5312-5320. Epub 2019 Jul 17. PMID: 31314750
Article Published Date : Jul 16, 2019
Study Type : Animal Study
Additional Links
Substances : Sesamin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective , Wnt/β-catenin signaling pathway modulation
Severe magnesium deficiency compromises systemic bone mineral density and aggravates inflammatory bone resorption. Add to My Research
Pubmed Data : J Nutr Biochem. 2019 Nov 26 ;77:108301. Epub 2019 Nov 26. PMID: 31825817
Article Published Date : Nov 25, 2019
Study Type : Animal Study
Additional Links
Substances : Magnesium
Additional Keywords : Increased Risk
Silymarin exhibits antiosteoporotic and selective estrogen receptor modulator activity in ovariectomized rats. Add to My Research
Pubmed Data : Phytomedicine. 2010 Feb;17(2):116-25. Epub 2009 Jul 3. PMID: 19577454
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Substances : Milk Thistle
Diseases : Osteoporosis
Pharmacological Actions : Selective estrogen enzyme modulator (SEEM), Selective Estrogen Receptor Modulators
Additional Keywords : Estrogen Receptor Beta, Plant Extracts
Soy moderately improves microstructural properties (bone quality) without affecting bone mass (bone density) in an ovariectomized rat model of osteoporosis. Add to My Research
Pubmed Data : Bone. 2006 May;38(5):686-93. Epub 2006 Jan 10. PMID: 16406762
Article Published Date : May 01, 2006
Study Type : Animal Study
Additional Links
Substances : Isoflavones, Soy Protein
Diseases : Osteoporosis
Additional Keywords : Bone Quality
TA-65 dietary supplementation in female mice leads to an improvement of certain health-span indicators including glucose tolerance, osteoporosis and skin fitness, without significantly increasing global cancer incidence. Add to My Research
Pubmed Data : Aging Cell. 2011 Aug ;10(4):604-21. Epub 2011 Apr 14. PMID: 21426483
Article Published Date : Aug 01, 2011
Study Type : Animal Study
Additional Links
Substances : TA-65 (Astragalus compound)
Pharmacological Actions : Anticarcinogenic Agents, Telomerase Upregulation
Tanshinone‑IIA attenuates the deleterious effects of oxidative stress in osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 May ;17(5):6969-6976. Epub 2018 Mar 14. PMID: 29568934
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Osteoporosis, Oxidative Stress
The bone protective effect of green tea polyphenols on bone loss may be due to its antioxidant qualities. Add to My Research
Pubmed Data : 1: Osteoporos Int. 2008 Jul;19(7):979-90. Epub 2007 Dec 15. PMID:18084689
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Green Tea
Diseases : Osteoporosis
The combination of FOS and dried plum is capable of reversing ovariectomy induced bone loss. Add to My Research
Pubmed Data : Helicobacter. 2009 Aug;14(4):280-5. PMID: 20132045
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Substances : FOS (Fructooligosaccharides), Plum
Diseases : Osteopenia, Osteoporosis
The combination of soy and FOS reverse the loss of certain microarchitectural parameters of the bone in osteopenic rats. Add to My Research
Pubmed Data : Menopause. 2006 Jul-Aug;13(4):692-9. PMID: 16837891
Article Published Date : Jul 01, 2006
Study Type : Animal Study
Additional Links
Substances : FOS (Fructooligosaccharides), Soy Protein
Diseases : Osteopenia, Osteoporosis
The hydroalcoholic extract of the Psidium guajava fruit prevented ovariectomized-induced bone loss in animals. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Med Sci. 2018 Nov ;43(6):623-632. PMID: 30510339
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Guava
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2019 ;13:3497-3514. Epub 2019 Oct 7. PMID: 31631974
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Kaempferol
Diseases : Fractures: Bone, Osteoporosis
The results suggest neohesperidin possesses therapeutic potential as a natural anti-catabolic treatment in osteoporosis. Add to My Research
Pubmed Data : Mol Cell Endocrinol. 2017 Jan 5 ;439:369-378. Epub 2016 Sep 21. PMID: 27664516
Article Published Date : Jan 04, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : neohesperidin
Diseases : Osteoporosis
Pharmacological Actions : Anti-Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Ovariectomy-Induced Changes
The sulfated polysaccharide fucoidan stimulates osteogenic differentiation of human adipose-derived stem cells, indicating it may it may be a potential candidate for promoting bone regeneration. Add to My Research
Pubmed Data : Stem Cells Dev. 2012 Aug 10 ;21(12):2204-11. Epub 2011 Dec 19. PMID: 22050637
Article Published Date : Aug 10, 2012
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Bone Destructive Diseases: Over-Active Osteoclasts, Bone Fractures, Hip Fracture, Osteoporosis
Pharmacological Actions : Osteogenic
Additional Keywords : Bone Regeneration
Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats. Add to My Research
Pubmed Data : Biomed Pharmacother. 2018 Oct ;106:1339-1347. Epub 2018 Jul 23. PMID: 30119205
Article Published Date : Sep 30, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Black Tea
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
These findings suggest that gastrodin alleviated glucocorticoid-induced osteoporosis. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2018 Feb 20 ;9(14):11528-11540. Epub 2018 Jan 3. PMID: 29545917
Article Published Date : Feb 19, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Gastrodin
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Osteogenic
These results suggest that emodin may be a promising alternative agent for osteoporosis in combination therapy. Add to My Research
Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2017 Oct 1 ;49(10):867-878. PMID: 28981600
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
These results suggest that O. humifusa supplementation has a positive effect on bone density. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2012 ;13(6):6747-56. Epub 2012 Jun 4. PMID: 22837661
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
These results support the potential of resveratrol to suppress periodontitis-mediated tissue damages. Add to My Research
Pubmed Data : Acta Biomater. 2016 Jan ;29:398-408. Epub 2015 Oct 20. PMID: 26497626
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Arthritis, Lipopolysaccharide-Induced Toxicity, Osteoporosis, Periodontal Diseases, Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
This study found that dietary intake of Fenugreek seeds can improve the bone structure and biomechanical properties in ovariectomized rats. Add to My Research
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ethiop J Health Sci. 2018 Nov ;28(6):787-794. PMID: 30607096
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Fenugreek
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
This study provides a potential treatment candidate for glucocorticoid-induced osteoporosis. Add to My Research
Pubmed Data : Chem Biol Interact. 2016 Aug 25 ;256:188-97. Epub 2016 Jul 5. PMID: 27387537
Article Published Date : Aug 24, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Problem Substances : Dexamethasone
This suggests that diosgenin might prevent bone loss during aging and provide beneficial effects in osteoporosis in the elderly. Add to My Research
Pubmed Data : Chin J Physiol. 2014 Jun 30 ;57(3):121-7. PMID: 24826780
Article Published Date : Jun 29, 2014
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Pharmacological Actions : Osteoprotective
Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Metab. 2019 ;2019:1431384. Epub 2019 Mar 31. PMID: 31049223
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
Thymoquinone inhibited lipopolysaccharide (LPS) induced bone resorption by suppressing the osteoclastogenesis. Add to My Research
Pubmed Data : Pharmacol Res. 2015 Sep ;99:63-73. Epub 2015 May 28. PMID: 26022736
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
Additional Keywords : Gene Expression Regulation
Pubmed Data : Clin Exp Pharmacol Physiol. 2005 Sep;32(9):761-70. PMID: 16173934
Article Published Date : Sep 01, 2005
Study Type : Animal Study
Additional Links
Substances : Tocotrienols, Vitamin E
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation
Total extract and standardized fraction from the stem bark of Butea monosperma have osteoprotective action. Add to My Research
Pubmed Data : Menopause. 2010 May-Jun;17(3):602-10. PMID: 20395887
Article Published Date : Apr 30, 2010
Study Type : Animal Study
Additional Links
Substances : Palash
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Ursolic acid might be a potential therapeutic of retinoic acid-induced acute osteoporosis. Add to My Research
Pubmed Data : Chin J Integr Med. 2019 Mar ;25(3):210-215. Epub 2018 Aug 30. PMID: 30159645
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Problem Substances : Retinoic Acid
Using Pueraria mirifica and miroestrol as alternative hormone replacement therapy of E2 might be beneficial. Add to My Research
Pubmed Data : Fitoterapia. 2012 Dec ;83(8):1687-92. Epub 2012 Oct 4. PMID: 23041523
Article Published Date : Nov 30, 2012
Study Type : Animal Study
Additional Links
Substances : Pueraria mirifica
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Gene Expression Regulation, Osteoporosis, Osteoprotective, Ovariectomy-Induced Changes, Pueraria mirifica
Virgin coconut oil prevented lipid peroxidation and increased the antioxidant enzymes in the osteoporotic rat model. Add to My Research
Pubmed Data : Evid Based Complement Alternat Med. 2012 ;2012:525079. Epub 2012 Aug 15. PMID: 22927879
Article Published Date : Jan 01, 2012
Study Type : Animal Study
Additional Links
Substances : Coconut Oil
Diseases : Lipid Peroxidation, Osteoporosis, Ovariectomy Associated Adverse Changes, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Ovariectomy-Induced Changes
Copyright: rob3000 / 123RF Stock Photo
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Professional education events are heavily sponsored by drug companies promoting their products as the solution. This widely used coercive and misinformation technique where drug benefits are exaggerated and side effects minimized was exposed in a recent BMJ Open study.
Written by Sayer Ji, Founder
The present-day definitions of Osteoporosis and Osteopenia were arbitrarily conceived by the WHO in the early 90's and then projected upon millions of women's bodies seemingly in order to convince them they had a drug-treatable, though symptomless, disease
Written by Sayer Ji, Founder
What if everything your doctor told you about osteoporosis and osteopenia was wrong?
Written by Case Adams, Naturopath
Research is discovering what ancient Japanese and Chinese medicine already knew: That dried plums slow the aging process with respect to bone loss
Written by Sayer Ji, Founder
When older women are told that their bones should be as dense as a young adult (30 year old) at peak bone mass, things can and DO go terribly wrong...
Written by Sayer Ji, Founder
The human fascination with spices is as old as cultural time itself. There is an obvious beauty to the various aromas and flavors these plant extracts express (have you smelled cumin lately?), and undoubtedly these first drew us closer to them, but our primordial relationship with them involves much more than aesthetic infatuation.
Written by Sayer Ji, Founder
An ancient fermented food puts pharmaceutical drugs for bone loss to shame...