Osteoporosis

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182 Substances Researched for Osteoporosis
NameACCKFocus
Vitamin K218106Locked
Vitamin K19103Locked
Vitamin D1482Locked
Vitamin C1168Locked
Vitamin K2: Menaquinone-7956Locked
Soy652Locked
Magnesium550Locked
Natto 550Locked
Plum745Locked
Genistein941Locked
Isoflavones432Locked
Calcium625Locked
Green Tea525Locked
Hops322Locked
Strontium321Locked
Vitamin K2: (MK-4)321Locked
phytoestrogens321Locked
Berberine618Locked
Black Tea416Locked
Boron414Locked
Soy Protein 314Locked
Cryptoxanthin413Locked
Puerarin713Locked
Curcumin712Locked
Fruit: All312Locked
Melatonin212Locked
DHEA (Dehydroepiandrosterone)211Locked
Vegetables: All 211Locked
Beer110Locked
Black Cohosh110Locked
Carotenoids110Locked
Eicosapentaenoic acid (EPA) 110Locked
Fermented Foods and Beverages110Locked
Gamma-Linoleic Acid (GLA) 110Locked
Lactobacillus reuteri110Locked
Lycopene110Locked
Red Clover110Locked
Resveratrol710Locked
Silica: Orthosilicic acid110Locked
Diosgenin48Locked
Pueraria mirifica48Locked
Onion27Locked
Gastrodin36Locked
Hesperidin36Locked
Nigella sativa (aka Black Seed)36Locked
Pomegranate36Locked
Xylitol36Locked
Zinc46Locked
Citrus naringin35Locked
Fucoidan35Locked
Myricetin35Locked
Vitamin E35Locked
Black Raspberry24Locked
DHA (Docosahexaenoic Acid)24Locked
EGCG (Epigallocatechin gallate)24Locked
Emodin24Locked
FOS (Fructooligosaccharides)24Locked
Ginsenosides34Locked
Kudzu24Locked
Noni24Locked
Oleanolic acid24Locked
Olive Oil24Locked
Psychedelics:All 24Locked
Royal Jelly24Locked
Chlorogenic Acid23Locked
Flavonoids23Locked
Phloretin23Locked
Pomegranate Seed23Locked
Tanshinone IIA23Locked
Ursolic Acid23Locked
Whey23Locked
Xanthohumol23Locked
18β-Glycyrrhetinic Acid12Locked
Adlay12Locked
Alpha-Lipoic Acid22Locked
Antrodia camphorata12Locked
Arginine12Locked
Ashwagandha12Locked
B-complex22Locked
Basil12Locked
Bergamot orange12Locked
Beta-Caryophyllene12Locked
Blackberry12Locked
Blueberry12Locked
Chicory12Locked
Clove12Locked
Coconut Oil12Locked
Coenzyme Q1012Locked
Cordyceps Militaris12Locked
Cumin12Locked
Devils Claw12Locked
Dioscorea spongiosa12Locked
Equol12Locked
Fennel12Locked
Fenugreek12Locked
Grapefruit12Locked
Horsetail12Locked
Hu Zhang (Polygonum cuspidatum)12Locked
Kefir12Locked
Lactoferrin12Locked
Lysine12Locked
Maca12Locked
Magnolol12Locked
Maitake Mushroom12Locked
Manganese12Locked
Milk Thistle12Locked
Milk: Fermented12Locked
Mugwort12Locked
Mushrooms: All 12Locked
Nobiletin 12Locked
Oleuropein12Locked
Olive12Locked
Orange12Locked
Oyster Mushroom12Locked
Paeoniflorin12Locked
Palash12Locked
Parsley12Locked
Passion Flower12Locked
Phellinus Linteus12Locked
Polygonatum Sibiricum12Locked
Polyphenols12Locked
Prebiotics22Locked
Prickly Pear Cactus12Locked
Probiotics22Locked
Red Marine Algae12Locked
Red Yeast Rice12Locked
Rooibos12Locked
Rosemary12Locked
Safflower12Locked
Shiitake Mushroom 12Locked
Spinach12Locked
TA-65 (Astragalus compound)12Locked
Tangeretin 12Locked
Tart Cherry12Locked
Tea12Locked
Thyme12Locked
Thymoquinone12Locked
Tocotrienols12Locked
Vitamin E: Gamma-tocotrienol12Locked
Yacón12Locked
neohesperidin12Locked
Anise11Locked
Asiatic Acid11Locked
Avenanthramides11Locked
Bai Zhu11Locked
Baicalein11Locked
Barberry11Locked
Cannabidiol11Locked
Catechin 11Locked
Chamomile11Locked
Chrysanthemum Indicum11Locked
Cinnamon11Locked
Epimedium11Locked
Glycyrrhizin11Locked
Honeybush11Locked
Hydroxytyrosol11Locked
Icariin11Locked
Indole-3-Carbinol11Locked
Isoquercitrin11Locked
Ligustrazine11Locked
Loquat11Locked
Luteolin11Locked
Mangiferin11Locked
Marijuana11Locked
Nutmeg11Locked
Oats11Locked
Panax Notoginseng11Locked
Parthenolide11Locked
Persimmon 11Locked
Progesterone11Locked
Prune11Locked
Rehmannia11Locked
Sesamol11Locked
Sideritis11Locked
Thymol11Locked
Tomatidine 11Locked
Verbascoside11Locked
Vitamin A11Locked
Walnut11Locked
Water: Deep Sea11Locked
Zyflamend11Locked
Ipriflavone10Locked
28 Problem Substances Researched for Osteoporosis
NameACCKFocus
Bisphosphonates1048Locked
Gluten333Locked
Warfarin230Locked
Alendronate (trade name Fosamax) 827Locked
Rosiglitazone (trade name Avandia)526Locked
Proton-Pump Inhibitors424Locked
Arimidex110Locked
Aromatase Inhibitor Drugs110Locked
Aspirin 110Locked
Bumex110Locked
Coffee110Locked
Diuretic Drugs110Locked
Diuretic: Loop110Locked
Histamine Receptor Antagonists110Locked
Letrozole (trade name Femera)110Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)110Locked
Tamoxifen110Locked
Dexamethasone69Locked
Risedronate23Locked
Aluminium Cans12Locked
Sugary soda12Locked
Zoledronic Acid22Locked
Aluminum Chloride11Locked
Cow Milk21Locked
Etidronate 11Locked
Ibandronate11Locked
Pamidronate (trade name Aredia)11Locked
Thyroxine11Locked
13 Therapeutic Actions Researched for Osteoporosis
NameACCKFocus
Tai Chi560Locked
Sunlight exposure432Locked
Acupuncture120Locked
Exercise220Locked
Yoga220Locked
Dietary Modification: Less Acid/More Alkaline Foods110Locked
Fasting/Caloric Restriction110Locked
Hyperbaric Treatment110Locked
Dietary Modification: Wheat/Gluten Free24Locked
Electroacupuncture24Locked
Laser Treatment: Low-Level12Locked
Whole-Body Vibration 22Locked
Integrative Medicine11Locked
4 Problematic Actions Researched for Osteoporosis
NameACCKFocus
High Bone Density12111Locked
DXA Scans321Locked
Oophorectomy (Ovariectomy)110Locked
Western Diet24Locked
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View the Evidence:
493 Abstracts with Osteoporosis Research

[+]

Greater dietary vitamin C intake was associated with a lower risk of hip fracture and osteoporosisMar 31, 2018

Pubmed Data : Br J Nutr. 2018 Apr ;119(8):847-858. PMID: 29644950
Article Published Date : Mar 31, 2018
Study Type : Meta Analysis
Additional Links
Substances : Vitamin C
Diseases : Hip Fracture, Osteoporosis
Additional Keywords : Risk Reduction
[+]

High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women.Apr 01, 2009

Pubmed Data : Nutr Res. 2009 Apr;29(4):221-8. PMID: 19410972
Article Published Date : Apr 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K, Vitamin K2
Diseases : Bone Fractures, Osteoporosis, Postmenopausal Disorders
[+]

Long-term use of warfarin was associated with osteoporotic fractures, at least in men with atrial fibrillation. Jan 23, 2006

Pubmed Data : Arch Intern Med. 2006 Jan 23;166(2):241-6. PMID: 16432096
Article Published Date : Jan 23, 2006
Study Type : Meta Analysis
Additional Links
Diseases : Drug-Induced Toxicity , Osteoporosis
Problem Substances : Warfarin
[+]

Low serum level of magnesium seems to be a risk factor for osteoporosis among the postmenopausal women.May 31, 2014

Pubmed Data : Biol Trace Elem Res. 2014 Jun ;159(1-3):8-14. Epub 2014 Apr 12. PMID: 24728877
Article Published Date : May 31, 2014
Study Type : Meta Analysis
Additional Links
Substances : Magnesium
Diseases : Magnesium Deficiency, Osteoporosis
Additional Keywords : Risk Factors
[+]

Puerarin showed upregulating effects on bone mass in ovariectomy-induced postmenopausal osteoporosis.Jul 02, 2019

Pubmed Data : Curr Stem Cell Res Ther. 2019 Jul 3. Epub 2019 Jul 3. PMID: 31269886
Article Published Date : Jul 02, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Puerarin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Soy isoflavones prevent bone resorption and loss.Jul 09, 2019

Pubmed Data : Crit Rev Food Sci Nutr. 2019 Jul 10:1-15. Epub 2019 Jul 10. PMID: 31290343
Article Published Date : Jul 09, 2019
Study Type : Meta Analysis, Review
Additional Links
Substances : Isoflavones
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Tai chi is effective in improving balance of older adults and in the absence of other interventions, reduces falls in the nonfrail elderly.Jan 01, 2011

Pubmed Data : Altern Ther Health Med. 2011 Jan-Feb;17(1):40-8. PMID: 21614943
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Diseases : Bone Fractures, Elderly: Age Specific Diseases, Osteoporosis
Therapeutic Actions : Tai Chi
Additional Keywords : Risk Reduction
[+]

There was an association between the increase of at least one serving of fruits and vegetables per day and decreases in the risk of fractures.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(5):e0217223. Epub 2019 May 31. PMID: 31150426
Article Published Date : Dec 31, 2018
Study Type : Meta Analysis, Review
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Fractures: Bone, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

This present systematic review indicated that acupuncture could be an effective therapy for treating osteoporosis.Dec 31, 2017

Pubmed Data : Am J Chin Med. 2018 ;46(3):489-513. Epub 2018 Apr 4. PMID: 29614884
Article Published Date : Dec 31, 2017
Study Type : Meta Analysis, Review
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Acupuncture
Pharmacological Actions : Osteoprotective
[+]

Vitamin K1 and K2 exhibit anti-fracture activity.Dec 01, 2009

Pubmed Data : Clin Calcium. 2009 Dec;19(12):1805-14. PMID: 19949272
Article Published Date : Dec 01, 2009
Study Type : Meta Analysis
Additional Links
Substances : Vitamin K2
Diseases : Bone Fractures, Osteoporosis
[+]

A black cohosh extract is equipotent to conjugated estrogens in reducing menopausal symptoms and bone markers, without adverse effects. Mar 14, 2003

Pubmed Data : Maturitas. 2003 Mar 14;44 Suppl 1:S67-77. PMID: 12609561
Article Published Date : Mar 14, 2003
Study Type : Human Study
Additional Links
Substances : Black Cohosh
Diseases : Menopausal Syndrome, Osteoporosis
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

A specific exercise program targeting osteoporosis improves the condition of postmenopausal women with low bone density. Mar 01, 2009

Pubmed Data : 1: Clin Ter. 2009 Mar-Apr;160(2):105-9. PMID:19452097
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Exercise
[+]

Alendronate is associated with injury and ulceration of the gastric mucosa. Nov 01, 2000

Pubmed Data : Aliment Pharmacol Ther. 2000 Nov;14(11):1451-7. PMID: 11069316
Article Published Date : Nov 01, 2000
Study Type : Human Study
Additional Links
Diseases : Drug-Induced Toxicity: Gastrointestinal, Gastric Ulcer, Osteoporosis
Problem Substances : Alendronate (trade name Fosamax) , Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Gastrotoxic, Ulcerogenic
[+]

Alendronate use is associated with low-energy femoral shaft fractures. May 01, 2008

Pubmed Data : J Orthop Trauma. 2008 May-Jun;22(5):346-50. PMID: 18448990
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Alendronate (trade name Fosamax)
[+]

Although hip bone mineral density is strongly related to hip fracture risk in elderly white women, other clinical risk factors also are independent predictors of long-term risk.Sep 01, 2004

Pubmed Data : J Am Geriatr Soc. 2004 Sep;52(9):1479-86. PMID: 15341549
Article Published Date : Sep 01, 2004
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Diabetes Mellitus: Type 2, Hip Fracture, Osteoporosis, Parkinson's Disease, Vision Loss
Additional Keywords : Diseases that are Linked
[+]

Ambient air pollution was associated with lower bone mineral content in a young adult population in a peri-urban area of South India.Jan 02, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JAMA Netw Open. 2020 Jan 3 ;3(1):e1918504. Epub 2020 Jan 3. PMID: 31899531
Article Published Date : Jan 02, 2020
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Osteoporosis
Additional Keywords : Increased Risk
[+]

Arimidex therapy contributes in the decline of bone mineral density in early breast cancer patients.Jan 01, 2010

Pubmed Data : Bratisl Lek Listy. 2010;111(1):27-32. PMID: 20429308
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Additional Keywords : Drug: Tamoxifen
Problem Substances : Arimidex, Aromatase Inhibitor Drugs, Letrozole (trade name Femera)
[+]

Artemisia princeps as a promising therapeutic option for the improvement of postmenopausal osteoporosis.Dec 31, 2015

Pubmed Data : J Nutr Health Aging. 2016 ;20(5):533-9. PMID: 27102792
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Japanese mugwort
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Ascorbic acid may modify the composition of gut microbiota which plays a role in the pathogenesis of an inflammatory bowel disease.Jul 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jul 29 ;12(8). Epub 2020 Jul 29. PMID: 32751086
Article Published Date : Jul 28, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Inflammatory Bowel Diseases, Osteoporosis, Vitamin C Deficiency
Pharmacological Actions : Gastrointestinal Agents
[+]

Beer drinking contributes to higher bone density as a result of the phytoestrogen content (hops) of this alcoholic beverage. Oct 01, 2009

Pubmed Data : Nutrition. 2009 Oct;25(10):1057-63. Epub 2009 Jun 13. PMID: 19527924
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Beer, Hops, phytoestrogens
Diseases : Osteoporosis
[+]

Bisphosphonate use in chronic kidney disease is associated wtih adynamic bone disease.Jan 01, 2010

Pubmed Data : Blood Purif. 2010;29(3):293-9. Epub 2010 Jan 21. PMID: 20090316
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Kidney Diseases, Kidney Failure: Chronic, Osteoporosis
Additional Keywords : Diseases that are Linked
Problem Substances : Bisphosphonates
[+]

Bisphosphonates used for osteoporosis in patients with cystic fibrosis increases bone mineral density without increasing bone quality/strength, while causing bone pain and flu-like symptoms. Jan 01, 2009

Pubmed Data : Cochrane Database Syst Rev. 2009(4):CD002010. Epub 2009 Oct 7. PMID: 19821288
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Cystic Fibrosis, Osteoporosis
Problem Substances : Bisphosphonates
[+]

Bone mineral density is a significant prognostic factor for postmenopausal Caucasian women with breast cancer. Low bone mineral density is associated with a lower local and distant rate of recurrence.Feb 28, 2013

Pubmed Data : Breast J. 2013 Mar-Apr;19(2):168-72. Epub 2013 Feb 13. PMID: 23406171
Article Published Date : Feb 28, 2013
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
[+]

Calcium supplementation (without vitamin D) is associated with increased risk of bone fracture.Aug 01, 2008

Pubmed Data : Osteoporos Int. 2008 Aug;19(8):1119-23. Epub 2008 Feb 20. PMID: 18286218
Article Published Date : Aug 01, 2008
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Osteoporosis
[+]

Calcium supplementation may actually increase the risk of bone fracture.Dec 01, 2007

Pubmed Data : Am J Clin Nutr. 2007 Dec;86(6):1780-90. PMID: 18065599
Article Published Date : Dec 01, 2007
Study Type : Human Study
Additional Links
Substances : Calcium
Diseases : Hip Fracture, Osteoporosis
[+]

Carotenoids such as lycopene have a protective effect on bone health.Jun 01, 2009

Pubmed Data : J Bone Miner Res. 2009 Jun;24(6):1086-94. PMID: 19138129
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Substances : Carotenoids, Lycopene
Diseases : Osteoporosis
[+]

Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2017 Sep ;106(3):909-920. Epub 2017 Aug 2. PMID: 28768651
Article Published Date : Aug 31, 2017
Study Type : Human Study
Additional Links
Substances : Isoflavones, Probiotics, Red Clover
Diseases : Osteoporosis, Postmenopausal Disorders
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Correcting Dysbiosis may help to correct malabsorption and resulting bone disease.May 01, 2001

Pubmed Data : Dig Dis Sci. 2001 May;46(5):1077-82. PMID: 11341652.PMID:11341652
Article Published Date : May 01, 2001
Study Type : Human Study
Additional Links
Diseases : Dysbiosis, Osteoporosis
[+]

DHEA supplementation improved lower extremity strength and function in older, frail women involved in a gentle exercise program of chair aerobics or yoga.Oct 25, 2008

Pubmed Data : Pharmacol Biochem Behav. 2008 Oct 25. [Epub ahead of print] PMID: 20863330
Article Published Date : Oct 25, 2008
Study Type : Human Study
Additional Links
Substances : DHEA (Dehydroepiandrosterone)
Diseases : Elderly: Age Specific Diseases, Osteoporosis
Additional Keywords : Sex Hormone-Binding Globulin
[+]

Dietary magnesium may play a role in musculoskeletal health.Oct 29, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Oct 30 ;9(11). Epub 2017 Oct 30. PMID: 29084183
Article Published Date : Oct 29, 2017
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Bone Fractures, Osteoporosis, Sarcopenia
Pharmacological Actions : Osteoprotective
[+]

Dietary vitamin K2 supplement improves bone status after lung and heart transplantation.Feb 27, 2010

Pubmed Data : Transplantation. 2010 Feb 27;89(4):458-64. PMID: 20177349
Article Published Date : Feb 27, 2010
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: Menaquinone-7
Diseases : Organ Transplantation, Organ Transplantation: Heart, Organ Transplantation: Lung, Osteoporosis
[+]

Dried plum improves bone mineral density in postmenopausal women. May 31, 2011

Pubmed Data : Br J Nutr. 2011 May 31:1-8. Epub 2011 May 31. PMID: 21736808
Article Published Date : May 31, 2011
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteoporosis, Postmenopausal Disorders
[+]

Dried plum in its whole form is a promising and efficacious functional food therapy for preventing bone loss in postmenopausal women.May 13, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 May 14 ;9(5). Epub 2017 May 14. PMID: 28505102
Article Published Date : May 13, 2017
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Dried plums improve indices of bone formation in postmenopausal women.Mar 01, 2010

Pubmed Data : Altern Ther Health Med. 2010 Mar-Apr;16(2):12-4. PMID: 11860726
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteoporosis
[+]

Drinking up to 3 cups of tea per day was associated with a 30% reduction in the risk of hip fractures in women.Oct 31, 1995

Article Published Date : Oct 31, 1995
Study Type : Human Study
Additional Links
Substances : Green Tea
Diseases : Osteoporosis
[+]

DXA-generated Z-scores and T-scores may differ substantially and significantly in young adults.Oct 01, 2007

Pubmed Data : J Clin Densitom. 2007 Oct-Dec;10(4):351-8. Epub 2007 Jul 26. PMID: 17662630
Article Published Date : Oct 01, 2007
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Additional Keywords : T-Score/Z-Score Mythology
Anti Therapeutic Actions : DXA Scans
[+]

Elderly women with high bone mineral density (BMD) have up to 2.7 times greater risk of breast cancer, especially advanced cancer, compared with women with low BMD.Jun 20, 2001

Pubmed Data : J Natl Cancer Inst. 2001 Jun 20;93(12):930-6. PMID: 11416114
Article Published Date : Jun 20, 2001
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Obesity, Osteoporosis
Anti Therapeutic Actions : High Bone Density
[+]

Gamma-linolenic acid (GLA) and Eicosapentaenoic acid (EPA) have beneficial effects on bone in elderly patients. Oct 01, 1998

Pubmed Data : Aging (Milano). 1998 Oct;10(5):385-94. PMID: 9932142
Article Published Date : Oct 01, 1998
Study Type : Human Study
Additional Links
Substances : Eicosapentaenoic acid (EPA) , Gamma-Linoleic Acid (GLA)
Diseases : Osteoporosis
[+]

Genistein compares favorably to HRT in supporting bone health in early postmenopausal women.Oct 01, 2002

Pubmed Data : J Bone Miner Res. 2002 Oct;17(10):1904-12. PMID: 12369794
Article Published Date : Oct 01, 2002
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Osteopenia, Osteoporosis, Postmenopausal Disorders
Additional Keywords : HRT Alternatives, Natural Substances Versus Drugs
[+]

Genistein has a positive effect on bone metabolism in osteopenic postmenopausal women, without increasing endometrial thickness. Jun 19, 2007

Pubmed Data : Ann Intern Med. 2007 Jun 19;146(12):839-47. PMID: 17577003
Article Published Date : Jun 19, 2007
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Osteoporosis
[+]

Genistein is safe and effective in improving bone density without adverse responses in breast density or endometrium thickness in osteopenic, postmenopausal women. Dec 01, 2008

Pubmed Data : J Clin Endocrinol Metab. 2008 Dec;93(12):4787-96. Epub 2008 Sep 16. PMID: 18796517
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Substances : Genistein
Diseases : Osteopenia, Osteoporosis
[+]

Green and yellow vegetable consumption is effective for maintaining bone mass in young women. Jan 01, 2009

Pubmed Data : 1: Tohoku J Exp Med. 2009;218(2):149-54. PMID:19478471
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Substances : Fruit: All, Vegetables: All
Diseases : Osteoporosis
[+]

Group exercise has a positive effect on postmenopausal osteoporosis and osteopenia.Aug 01, 2009

Pubmed Data : Acta Orthop Traumatol Turc. 2009 Aug-Oct;43(4):343-50. PMID: 19809232
Article Published Date : Aug 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Therapeutic Actions : Exercise
[+]

High consumption of coffee seems to contribute to a reduction in BMD Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Metab (Lond). 2010 ;7:12. Epub 2010 Feb 22. PMID: 20175915
Article Published Date : Dec 31, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Coffee
[+]

High prevalence of vitamin D deficiency and osteoporosis in patients with fragility fractures of hip.Oct 31, 2019

Pubmed Data : J Clin Orthop Trauma. 2019 Nov-Dec;10(6):1097-1100. Epub 2019 Mar 21. PMID: 31708635
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Higher bone density (upper 33%) is associated with a 2-fold increased risk of breast cancer.Mar 01, 2003

Pubmed Data : Bone. 2003 Mar;32(3):211-6. PMID: 12667548
Article Published Date : Mar 01, 2003
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Additional Keywords : Diseases that are Linked
Anti Therapeutic Actions : High Bone Density
[+]

Higher bone mass is associated with greater risk for breast cancer.Mar 20, 2007

Pubmed Data : Maturitas. 2007 Mar 20;56(3):312-21. Epub 2006 Oct 17. PMID: 17049767
Article Published Date : Mar 20, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
[+]

Higher bone mineral density is associated with higher incidence of estrogen receptor positive breast cancer.Jul 20, 2007

Pubmed Data : Maturitas. 2007 Jul 20;57(3):221-5. Epub 2007 Jan 19. PMID: 17240090
Article Published Date : Jul 20, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
[+]

Hop rho iso-alpha acids, berberine, vitamin D(3) and vitamin K (1) favorably impact biomarkers of bone turnover in postmenopausal women. Dec 19, 2009

Pubmed Data : J Bone Miner Metab. 2009 Dec 19. Epub 2009 Dec 19. PMID: 20024591
Article Published Date : Dec 19, 2009
Study Type : Human Study
Additional Links
Substances : Berberine, Hops, Vitamin D, Vitamin K
Diseases : Osteoporosis
[+]

In a healthy middle aged population with normal BMD, an increase in plant food consumption, either alone or in combination with a diet containing meat, is associated with improved bone mineralisation markers.Jan 01, 2020

Pubmed Data : J Nutr Health Aging. 2020 ;24(4):388-397. PMID: 32242206
Article Published Date : Jan 01, 2020
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
[+]

Increase in lumbar spine and femoral neck bone mineral density is associated with a 2.1 fold and 1.5 fold respectively, higher risk of breast cancer.Jul 31, 2000

Pubmed Data : Maturitas. 2000 Jul 31;36(1):27-34. PMID: 10989239
Article Published Date : Jul 31, 2000
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Additional Keywords : Breast
Anti Therapeutic Actions : High Bone Density
[+]

Intake of fermented soybean (natto) increases circulating vitamin K2 and osteocalcin (a marker for bone formation) in normal individuals. Jan 01, 2000

Pubmed Data : J Bone Miner Metab. 2000;18(4):216-22. PMID: 10874601
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Substances : Natto , Vitamin K
Diseases : Osteoporosis
Pharmacological Actions : Secretagogue
[+]

Isoflavones attenuate bone loss and have a potentially protective effect on the lumbar spine in womenFeb 01, 2004

Pubmed Data : Am J Clin Nutr. 2004 Feb;79(2):326-33. PMID: 14749241
Article Published Date : Feb 01, 2004
Study Type : Human Study
Additional Links
Substances : Isoflavones, Red Clover
Diseases : Osteoporosis
[+]

Lactobacillus reuteri reduces bone loss in older women with low bone mineral density.Jun 20, 2018

Pubmed Data : J Intern Med. 2018 Jun 21. Epub 2018 Jun 21. PMID: 29926979
Article Published Date : Jun 20, 2018
Study Type : Human Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Long term use of vitamin C supplements was associated with a higher BMD in the early postmenopausal years and among never users of oestrogen.Sep 30, 1997

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Epidemiol Community Health. 1997 Oct ;51(5):479-85. PMID: 9425455
Article Published Date : Sep 30, 1997
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Osteoporosis
[+]

Long-term proton pump inhibitor therapy is associated with an increased risk of hip fracture.Dec 27, 2006

Pubmed Data : JAMA. 2006 Dec 27;296(24):2947-53. PMID: 17190895
Article Published Date : Dec 27, 2006
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Hip Fracture, Osteoporosis
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term proton pump inhibitors use is associated with risk of bone complications.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Tunis Med. 2018 Mar ;96(3):193-197. PMID: 30325487
Article Published Date : Feb 28, 2018
Study Type : Human Study
Additional Links
Diseases : Bone Diseases, Osteoporosis
Additional Keywords : Increased Risk
Problem Substances : Proton-Pump Inhibitors
[+]

Long-term ultra-high hydrostatic pressurized brown rice intake prevents bone mineral density decline in elderly Japanese individuals.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2019 ;65(Supplement):S88-S92. PMID: 31619654
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Brown Rice
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Long-term use of bisphosphonates is assocated with low-energy femoral fractures. Jan 01, 2009

Pubmed Data : Drug Saf. 2009;32(9):775-85. PMID: 19670917
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Bisphosphonates
[+]

Low levels of serum ascorbic acid in elderly patients with hip fracture.Apr 30, 1998

Pubmed Data : Scand J Clin Lab Invest. 1998 May ;58(3):225-8. PMID: 9670346
Article Published Date : Apr 30, 1998
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Hip Fracture, Osteoporosis
[+]

Magnesium deficiency may contribute to osteoporosis promotion associated with gluten-sensitive enteropathy.Jan 01, 1996

Pubmed Data : Osteoporos Int. 1996;6(6):453-61. PMID: 9116391
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Celiac Disease, Magnesium Deficiency, Osteoporosis
Additional Keywords : Diseases that are Linked
[+]

Magnesium may have beneficial effects in reducing bone loss associated with high bone turnover, such as age-related osteoporosis. Dec 27, 2002

Pubmed Data : J Biol Chem. 2002 Dec 27;277(52):50341-7. Epub 2002 Oct 16. PMID: 9709941
Article Published Date : Dec 27, 2002
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Osteoporosis
[+]

Mammographic breast density is inversely associated with bone mineral density in the perimenopausal women.Aug 01, 2007

Pubmed Data : Ann Epidemiol. 2007 Aug;17(8):575-83. Epub 2007 May 29. PMID: 17532645
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Additional Keywords : Diseases that are Linked
Anti Therapeutic Actions : High Bone Density
[+]

Maximal dose-response of vitamin-K2 (menaquinone-4) on undercarboxylated osteocalcin in women with osteoporosis.Dec 31, 2019

Pubmed Data : Int J Vitam Nutr Res. 2020 Jan ;90(1-2):42-48. Epub 2019 Feb 28. PMID: 30816822
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Substances : Vitamin K2: (MK-4)
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Menaquinone-7 (vitamin K2) supplementation increases osteocalcin carboxylation associated with improved bone quality.Oct 01, 2009

Pubmed Data : Br J Nutr. 2009 Oct;102(8):1171-8. Epub 2009 May 19. PMID: 19450370
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Bone Fractures, Osteoporosis
[+]

MK-7 in addition to ordinary meals could improve osteocalcin γ-carboxylation status.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2015 ;61(6):471-80. PMID: 26875489
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

More than 10,000 steps daily may be needed to maintain bone mineral density.Dec 01, 2011

Pubmed Data : Osteoporos Int. 2011 Dec ;22(12):2981-8. Epub 2011 Feb 12. PMID: 21318440
Article Published Date : Dec 01, 2011
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Exercise
[+]

Most of the increase in mortality following hip and pelvic fractures is due to underlying conditions and probably would not be affected by reductions in the incidence of these fractures.Jul 22, 1996

Pubmed Data : Arch Intern Med. 1996 Jul 22;156(14):1521-5. PMID: 8687260
Article Published Date : Jul 22, 1996
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Elderly: Age Specific Diseases, Hip Fracture, Osteoporosis
Additional Keywords : Osteoporosis Myths
[+]

Multiple hyperbaric oxygen treatments has the possibility of contributing to recovery acceleration in patients with transient osteoporosis of the hip.Oct 31, 2016

Pubmed Data : Undersea Hyperb Med. 2016 Nov-Dec;43(7):847-854. PMID: 28777523
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Hyperbaric Treatment
[+]

Natto, a rich source of vitamin K2, promotes bone formation in premenopausal women. Apr 01, 2004

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2004 Apr;50(2):114-20. PMID: 15242015
Article Published Date : Apr 01, 2004
Study Type : Human Study
Additional Links
Substances : Natto , Vitamin K
Diseases : Osteoporosis
[+]

Neuromuscular and visual impairments (as well as femoral-neck BMD) are significant and independent predictors of the risk of hip fracture in elderly women. Jul 20, 1996

Pubmed Data : Lancet. 1996 Jul 20;348(9021):145-9. PMID: 8684153
Article Published Date : Jul 20, 1996
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Hip Fracture, Osteoporosis
Additional Keywords : Osteoporosis Myths
[+]

one-year treatment with melatonin increased bone mineral density at femoral neck in a dose-dependent manner, while high dose melatonin increased vBMD in the spine.Jun 02, 2015

Pubmed Data : J Pineal Res. 2015 Jun 3. Epub 2015 Jun 3. PMID: 26036434
Article Published Date : Jun 02, 2015
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Bone Fractures, Osteopenia, Osteoporosis
Pharmacological Actions : Osteogenic
Additional Keywords : Dose Response, Significant Treatment Outcome
[+]

Oophorectomy adversely affect healthy postmenopausal women by accelerating loss of bone mineral density (BMD) and the rate of increase in carotid artery intima-media thickness (CIMT).Mar 31, 2014

Pubmed Data : Fertil Steril. 2014 Apr ;101(4):1117-22. Epub 2014 Feb 14. PMID: 24530156
Article Published Date : Mar 31, 2014
Study Type : Human Study
Additional Links
Diseases : Atherosclerosis, Carotid Artery Narrowing, Intima Media Thickening , Osteoporosis, Osteoporosis: Age-Related
Additional Keywords : Ovariectomy-Induced Changes
Anti Therapeutic Actions : Oophorectomy (Ovariectomy)
[+]

Orthosilicic acid has therapeutic value in the treatment of osteopenia and osteoporosis. Jun 11, 2008

Pubmed Data : BMC Musculoskelet Disord. 2008 Jun 11;9:85. PMID: 18547426
Article Published Date : Jun 11, 2008
Study Type : Human Study
Additional Links
Substances : Silica: Orthosilicic acid
Diseases : Osteopenia, Osteoporosis
[+]

Osteoporosis rates are higher in adult patients with celiac disease.Mar 01, 1999

Pubmed Data : Bone. 1999 Mar;24(3):249-55. PMID: 10071918
Article Published Date : Mar 01, 1999
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Celiac Disease, Osteoporosis
Additional Keywords : Diseases that are Linked
[+]

Patients with Gaucher disease living in England have a high frequency of vitamin D deficiency Mar 01, 2009

Pubmed Data : Mol Genet Metab. 2009 Mar ;96(3):113-20. Epub 2009 Jan 14. PMID: 19147383
Article Published Date : Mar 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Gaucher Disease, Osteopenia, Osteoporosis, Vitamin D Deficiency
Additional Keywords : Bone Density, Lysosomal Storage Disorder
[+]

Prolonged intake of fermented soybean (natto) diets containing vitamin K2 (menaquinone-7) prevents bone loss in ovariectomized rats.Jan 01, 2000

Pubmed Data : J Bone Miner Metab. 2000;18(2):71-6. PMID: 10701161
Article Published Date : Jan 01, 2000
Study Type : Human Study
Additional Links
Substances : Natto , Vitamin K
Diseases : Osteopenia, Osteoporosis
[+]

Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients.Jul 01, 2010

Pubmed Data : Gastroenterology. 2010 Jul;139(1):93-101. Epub 2010 Mar 27. PMID: 20353792
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Diseases : Acid Reflux, Gastroesophageal Reflux, Osteoporosis
Problem Substances : Histamine Receptor Antagonists
[+]

Reduced bone density in patients on long-term warfarin.Jul 01, 2009

Pubmed Data : Int J Rheum Dis. 2009 Jul;12(2):130-5. PMID: 20374330
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Warfarin
[+]

Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes.Aug 01, 2010

Pubmed Data : Diabetes Obes Metab. 2010 Aug;12(8):716-21. PMID: 20590749
Article Published Date : Aug 01, 2010
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Diabetes Mellitus: Type 2, Hip Fracture, Osteoporosis
Problem Substances : Rosiglitazone (trade name Avandia)
[+]

Royal jelly consumption may ameliorate decreases in femoral bone mineral density and strength in postmenopausal women.Sep 02, 2020

Pubmed Data : Climacteric. 2020 Sep 3:1-7. Epub 2020 Sep 3. PMID: 32880201
Article Published Date : Sep 02, 2020
Study Type : Human Study
Additional Links
Substances : Royal Jelly
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Serum leptin level affected in childhood CD is responsive to GFD. Oct 31, 2006

Pubmed Data : J Clin Gastroenterol. 2006 Nov-Dec;40(10):906-9. PMID: 17063109
Article Published Date : Oct 31, 2006
Study Type : Human Study
Additional Links
Diseases : Celiac Disease, Osteoporosis
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Leptin Down-Regulation
Problem Substances : Gluten
[+]

Soy food consumption may reduce the risk of fracture in postmenopausal women, particularly among those in the early years following menopause.Sep 12, 2005

Pubmed Data : Arch Intern Med. 2005 Sep 12;165(16):1890-5. PMID: 16157834
Article Published Date : Sep 12, 2005
Study Type : Human Study
Additional Links
Substances : Soy
Diseases : Bone Fractures, Osteoporosis
Additional Keywords : Risk Reduction
[+]

Soy isoflavones attenuate bone loss in early postmenopausal women. Sep 01, 2006

Pubmed Data : Eur J Nutr. 2006 Sep;45(6):327-34. Epub 2006 Jun 8. PMID: 16763748
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Substances : Isoflavones, Soy
Diseases : Osteoporosis
[+]

Soy phytoestrogen has a positive effect on bone turnover indicators in menopausal women with osteopenia. Dec 01, 1999

Pubmed Data : Hum Cell. 1999 Dec;12(4):189-96. PMID: 16255781
Article Published Date : Dec 01, 1999
Study Type : Human Study
Additional Links
Substances : phytoestrogens, Soy Protein
Diseases : Osteopenia, Osteoporosis, Postmenopausal Disorders
Pharmacological Actions : Insulin-Like Growth Factor Inhibition/Downregulation
[+]

Soy product consumption is inversely associated with the risk for hip fracture in men and women. Oct 01, 2009

Pubmed Data : Am J Epidemiol. 2009 Oct 1;170(7):901-9. Epub 2009 Aug 31. PMID: 19720865
Article Published Date : Oct 01, 2009
Study Type : Human Study
Additional Links
Substances : Isoflavones, Soy
Diseases : Hip Fracture, Osteoporosis
Additional Keywords : Risk Reduction
[+]

Soymilk and progesterone are beneficial for bone health when taken separately, but may cause bone loss if consumed together. Aug 01, 2004

Pubmed Data : Eur J Nutr. 2004 Aug;43(4):246-57. Epub 2004 Apr 14. PMID: 15309425
Article Published Date : Aug 01, 2004
Study Type : Human Study
Additional Links
Substances : Soy
Diseases : Osteoporosis
Additional Keywords : Adverse Interaction Between Natural Substances, Soy Milk
[+]

Strontium renalate is a safe and effective treatment for veterbral and hip osteoporosis.Mar 01, 2005

Pubmed Data : Curr Osteoporos Rep. 2005 Mar;3(1):30-4. PMID: 16036099
Article Published Date : Mar 01, 2005
Study Type : Human Study
Additional Links
Substances : Strontium
Diseases : Bone Fractures, Hip Fracture, Osteoporosis
Additional Keywords : Risk Reduction
[+]

Strontium renalate safely reduces the risk of fractures in elderly women with osteoporosis,Jul 01, 2006

Pubmed Data : J Bone Miner Res. 2006 Jul;21(7):1113-20. PMID: 16813532
Article Published Date : Jul 01, 2006
Study Type : Human Study
Additional Links
Substances : Strontium
Diseases : Osteoporosis
Additional Keywords : Fracture Reduction
[+]

Sunlight exposure ameliorates osteoporosis and hypovitaminosis in Parkinson's disease.Jan 01, 2011

Pubmed Data : Parkinsonism Relat Disord. 2011 Jan;17(1):22-6. Epub 2010 Nov 2. PMID: 21050796
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis, Vitamin D Deficiency
Therapeutic Actions : Sunlight exposure
[+]

Sunlight exposure ameliorates osteoporosis and vitamin D deficiency in hospitalized, elderly women with Alzheimer's disease. Aug 01, 2005

Pubmed Data : J Bone Miner Res. 2005 Aug;20(8):1327-33. Epub 2005 Apr 4. PMID: 16007329
Article Published Date : Aug 01, 2005
Study Type : Human Study
Additional Links
Diseases : Alzheimer's Disease, Elderly: Age Specific Diseases, Osteoporosis
Therapeutic Actions : Sunlight exposure
[+]

Sunlight exposure increases the bone mineral density of stroke patients who have vitamin-D deficient bones. Aug 12, 2003

Pubmed Data : 1: Neurology. 2003 Aug 12;61(3):338-42. PMID:12913194
Article Published Date : Aug 12, 2003
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Sunlight exposure
[+]

T'ai chi improves muscle strength, bone mineral density, and fear of falling in women with osteoarthritis.Mar 01, 2010

Pubmed Data : J Altern Complement Med. 2010 Mar;16(3):227-33. PMID: 20192907
Article Published Date : Mar 01, 2010
Study Type : Human Study
Additional Links
Diseases : Osteoarthritis, Osteoporosis
Therapeutic Actions : Tai Chi
[+]

Tai chi chun exercise is beneficial for retarding bone loss in weight-bearing bones in early postmenopausal women. May 01, 2004

Pubmed Data : 1: Arch Phys Med Rehabil. 2004 May;85(5):717-22. PMID:15129394
Article Published Date : May 01, 2004
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Tai Chi
[+]

Tai Chi has a beneficial effect on bone formation and bone resorption in breast cancer survivors.Jun 01, 2010

Pubmed Data : Clin Breast Cancer. 2010 Jun;10(3):224-9. PMID: 20497921
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Diseases : Breast Cancer: Recovery , Osteopenia, Osteoporosis
Therapeutic Actions : Tai Chi
[+]

Tai Chi may contribute to maintaining bone mineral density and reducing fracture rate in postmenopausal women. May 01, 2007

Pubmed Data : Arch Phys Med Rehabil. 2007 May;88(5):673-80. PMID: 17466739
Article Published Date : May 01, 2007
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Tai Chi
[+]

Tamoxifen usage is associated with bone loss in patients who continued to menstruate after adjuvant chemotherapy.Feb 01, 2006

Pubmed Data : J Clin Oncol. 2006 Feb 1;24(4):675-80. PMID: 16446340
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Additional Keywords : Drug: Tamoxifen
Problem Substances : Tamoxifen
[+]

Tea drinking is associated with preservation of hip structure in elderly women. Mar 01, 1996

Pubmed Data : J Pediatr Endocrinol Metab. 1996 Mar;9 Suppl 1:101-11. PMID: 17921409
Article Published Date : Mar 01, 1996
Study Type : Human Study
Additional Links
Substances : Black Tea, Green Tea
Diseases : Hip Fracture, Osteopenia, Osteoporosis
[+]

The combination of β-cryptoxanthin and vitamin C is inversely associated with the risk of developing osteoporosis in post-menopausal Japanese female subjects.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2016 ;62(3):185-91. PMID: 27465725
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Cryptoxanthin, Vitamin C
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Factors
[+]

The consumption of vitamin K2 rich fermented soybean food products may contribute to the relatively lower fracture risk of Japanese women. Apr 01, 2001

Pubmed Data : Nutrition. 2001 Apr;17(4):315-21. PMID: 11369171
Article Published Date : Apr 01, 2001
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Natto , Soy, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
Additional Keywords : Risk Reduction
[+]

The majority of those patients who will sustain a low-trauma fracture do not meet the T-score definition of osteoporosis. Conversely, younger individuals with BD in the osteoporotic range but no other risk factors have relatively low rates of fracture.Mar 01, 2012

Pubmed Data : Curr Osteoporos Rep. 2012 Mar ;10(1):28-41. PMID: 22274642
Article Published Date : Mar 01, 2012
Study Type : Human Study
Additional Links
Diseases : Bone Fractures, Osteopenia, Osteoporosis
Additional Keywords : T-Score/Z-Score Mythology
[+]

The use of rosiglitazone (Avandia) in type 2 diabetic patients is associated with an increased risk of heart failure and of some fractures, mainly in women. Jun 20, 2009

Pubmed Data : Lancet. 2009 Jun 20;373(9681):2125-35. Epub 2009 Jun 6. PMID: 19501900
Article Published Date : Jun 20, 2009
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Heart Failure, Myocardial Infarction, Osteoporosis
Additional Keywords : Drug: Metformin
Problem Substances : Rosiglitazone (trade name Avandia)
[+]

The Western-type diet results in mild acidosis and increased cortisol secretion which adversely effects bone metabolism. Jan 01, 2003

Pubmed Data : Am J Physiol Renal Physiol. 2003 Jan;284(1):F32-40. Epub 2002 Sep 24. PMID: 12388390
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Diseases : Acid-Base Imbalance, Acidosis, Osteoporosis
Therapeutic Actions : Dietary Modification: Less Acid/More Alkaline Foods
[+]

These result shows that pantothenic acid rich diet can protect bone loss from estrogen deficiency.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(8):5008-5018. Epub 2019 Aug 15. PMID: 31497217
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin B-5 (Pantothenic Acid)
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

These results confirm the ability of dried plum to prevent the loss of total body BMD in older osteopenic postmenopausal women.Feb 21, 2016

Pubmed Data : Osteoporos Int. 2016 Feb 22. Epub 2016 Feb 22. PMID: 26902092
Article Published Date : Feb 21, 2016
Study Type : Human Study
Additional Links
Substances : Plum
Diseases : Osteopenia, Osteoporosis
[+]

Thirty-nine percent of Hologic (Hologic, Inc., Bedford, MA) subjects and 30% of Lunar (GE Lunar, GE Madison, WI) subjects diagnosed with "osteoporosis" by T-score were reclassified as either "normal" or "osteopenia" when their Z-score was used.Jan 01, 2009

Pubmed Data : J Clin Densitom. 2009 Jan-Mar;12(1):11-6. PMID: 19195620
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Additional Keywords : T-Score/Z-Score Mythology
Anti Therapeutic Actions : DXA Scans
[+]

This study suggests that daily boron intake of 1 mg/L may affect bone metabolism in postmenopausal women positively.Jun 30, 2018

Pubmed Data : J Trace Elem Med Biol. 2018 Jul ;48:52-56. Epub 2018 Mar 7. PMID: 29773193
Article Published Date : Jun 30, 2018
Study Type : Human Study
Additional Links
Substances : Boron
Diseases : Boron Deficiency , Osteoporosis, Postmenopausal Complications
[+]

Treatment with loop diuretics affects bone turnover and decreases bone mineral density.Jan 01, 2006

Pubmed Data : J Bone Miner Res. 2006 Jan;21(1):163-70. Epub 2005 Oct 10. PMID: 16355285
Article Published Date : Jan 01, 2006
Study Type : Human Study
Additional Links
Diseases : Osteopenia, Osteoporosis
Problem Substances : Bumex, Diuretic: Loop, Diuretic Drugs
[+]

Treatment with proton pump inhibitors increases the rate of subsequent treatment with anti-osteoporotic drugs.Jul 01, 2010

Pubmed Data : Pharmacoepidemiol Drug Saf. 2010 Jul;19(7):763-9. PMID: 20582909
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Diseases : Acid Reflux, Osteoporosis
Additional Keywords : Downward Spiral of Drug Treatment
Problem Substances : Bisphosphonates
[+]

Use of proton pump inhibitors for 7 or more years is associated with a significantly increased risk of an osteoporosis-related fracture. There is an increased risk of hip fracture after 5 or more years exposure. Aug 12, 2008

Pubmed Data : CMAJ. 2008 Aug 12;179(4):319-26. PMID: 18695179
Article Published Date : Aug 12, 2008
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
[+]

Usual dietary intake of fermented soybeans (Natto) is associated with bone mineral density in premenopausal women.Jun 01, 2002

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2002 Jun;48(3):207-15. PMID: 12350079
Article Published Date : Jun 01, 2002
Study Type : Human Study
Additional Links
Substances : Natto
Diseases : Osteoporosis
[+]

Vitamin C supplement use appears to have a beneficial effect on levels of BMD, especially among postmenopausal women using concurrent estrogen therapy and calcium supplements.Dec 31, 2000

Pubmed Data : J Bone Miner Res. 2001 Jan ;16(1):135-40. PMID: 11149477
Article Published Date : Dec 31, 2000
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Osteoporosis
[+]

Vitamin D insufficiency is a common risk factor for osteoporosis associated with increased bone remodelling and low bone mass.Sep 30, 2016

Pubmed Data : J Midlife Health. 2016 Oct-Dec;7(4):163-168. PMID: 28096639
Article Published Date : Sep 30, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis, Vitamin D Deficiency
Additional Keywords : Risk Factors
[+]

Vitamin D3 and vitamin K2 have a therapeutic effect on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.May 01, 2008

Pubmed Data : J Nutr. 2008 May;138(5):954-63. PMID: 11180916
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin D, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Osteoporosis
[+]

Vitamin K2 (MK-4) may be beneficial in the maintenance of bone health in postmenopausal women.Feb 01, 2009

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2009 Feb;55(1):15-21. PMID: 19352059
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: (MK-4)
Diseases : Bone Fractures, Osteoporosis, Postmenopausal Disorders
[+]

Vitamin K2 had a positive effect on bone mineral density in osteoporotic adults with cerebral palsy.Jun 13, 2017

Pubmed Data : Brain Dev. 2017 Jun 14. Epub 2017 Jun 14. PMID: 28624135
Article Published Date : Jun 13, 2017
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Cerebral Palsy, Osteoporosis
[+]

Vitamin K2 improves hip bone geometry and bone strength indices in postmenopausal women. Jul 01, 2007

Pubmed Data : Osteoporos Int. 2007 Jul;18(7):963-72. Epub 2007 Feb 8. PMID: 17287908
Article Published Date : Jul 01, 2007
Study Type : Human Study
Additional Links
Substances : Vitamin K
Diseases : Osteoporosis
[+]

Vitamin K2 supplementation in dose of 90 µg/day performed a significant effect on reducing bone loss in postmenopausal women.Feb 13, 2020

Pubmed Data : Calcif Tissue Int. 2020 Feb 14. Epub 2020 Feb 14. PMID: 32060566
Article Published Date : Feb 13, 2020
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Risk Reduction
[+]

Vitamin K2 treatment in combination with calcium supplementation increases bone mineral density in the treatment of postmenopausal osteoporosis.Apr 01, 2006

Pubmed Data : J Obstet Gynaecol Res. 2006 Apr;32(2):230-4. PMID: 16594930
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Vitamin K2, Vitamin K2: (MK-4)
Diseases : Osteoporosis
[+]

vitamin Vitamin (2) works synergistically with alendronate on improving both osteocalcin carboxylation and BMD of femoral neck in postmenopausal women with osteoporosis.Jan 01, 2008

Pubmed Data : J Bone Miner Metab. 2008;26(3):260-4. Epub 2008 May 11. PMID: 18470667
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Vitamin K2
Diseases : Bone Fractures, Osteoporosis
Additional Keywords : Drug Synergy
[+]

Weight bearing yoga training has a positive effect on bone in postmenopausal women by slowing down bone resorption. Sep 01, 2009

Pubmed Data : J Med Assoc Thai. 2009 Sep;92 Suppl5:S102-8. PMID: 19891384
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
[+]

Women in the lowest quartile of bone mass appear to be protected against breast cancer. Aug 01, 2001

Pubmed Data : Breast. 2001 Aug;10(4):313-7. PMID: 14965600
Article Published Date : Aug 01, 2001
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
[+]

Women with a positive family history of breast cancer and who are in the highest tertile bone mineral density are at a 3.41-fold increased risk compared with women in the lowest tertile.Jul 01, 1998

Pubmed Data : Am J Epidemiol. 1998 Jul 1;148(1):22-9. PMID: 9663400
Article Published Date : Jul 01, 1998
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
[+]

Women with bone mineral density above the 25th percentile have 2.0 to 2.5 times increased risk of breast cancer compared with women below the 25th percentile. Nov 06, 1996

Pubmed Data : JAMA. 1996 Nov 6;276(17):1404-8. PMID: 8892715
Article Published Date : Nov 06, 1996
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
[+]

Women with highest tertile bone mineral density (BMD) measured at the Ward's triangle and at the femoral neck are respectively at 2.2-and 3.3-fold increased risk of breast cancer compared with women at the lowest tertile of BMD. Jan 01, 2004

Pubmed Data : Eur J Epidemiol. 2004;19(8):785-92. PMID: 15469036
Article Published Date : Jan 01, 2004
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Osteoporosis
Anti Therapeutic Actions : High Bone Density
[+]

Yoga appears to raise bone mineral density in the spine and the femur safely.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Top Geriatr Rehabil. 2016 Apr ;32(2):81-87. Epub 2015 Nov 5. PMID: 27226695
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Yoga
Pharmacological Actions : Osteogenic, Osteoprotective
[+]

Yoga may be an alternative physical activity for the rehabilitation of osteoporotic subjects.Feb 18, 2010

Pubmed Data : Eur J Phys Rehabil Med. 2010 Feb 18. Epub 2010 Feb 18. PMID: 20332729
Article Published Date : Feb 18, 2010
Study Type : Human Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Yoga
[+]

Epigallocatechin-3-gallate enhances the osteoblastogenic differentiation of human adipose-derived stem cells.Jan 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2019 ;13:1311-1321. Epub 2019 Apr 23. PMID: 31114166
Article Published Date : Jan 01, 2019
Study Type : Human In Vitro
Additional Links
Substances : Catechin , Tea
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Regenerative
Additional Keywords : Bone Regeneration
[+]

Onion juice consumption showed a positive modulatory effect on the bone loss and bone mineral density.Feb 16, 2016

Pubmed Data : Food Funct. 2016 Feb 17 ;7(2):902-12. PMID: 26686359
Article Published Date : Feb 16, 2016
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Onion
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants
[+]

Radix astragalus isoflavones exhibit osteogenic activity.Jan 01, 2018

Pubmed Data : Phytother Res. 2018 Jan ;32(1):115-124. Epub 2017 Oct 18. PMID: 29044703
Article Published Date : Jan 01, 2018
Study Type : Human In Vitro
Additional Links
Substances : Astragalus
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic
[+]

The results of the present study suggested that vitamin K2 targets miR-133a to regulate osteogenesis.Apr 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 May ;15(5):2473-2480. Epub 2017 Mar 9. PMID: 28447758
Article Published Date : Apr 30, 2017
Study Type : Human In Vitro
Additional Links
Substances : Vitamin K2
Diseases : Osteonecrosis, Osteoporosis
Pharmacological Actions : MicroRNA modulator, Osteogenic
[+]

Calcium, Vitamin D and a Gluten-Free diet decreased bone pain and improved muscle strength.Dec 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Arch Osteoporos. 2011 Dec ;6(1-2):209-213. Epub 2011 Jun 15. PMID: 22207878
Article Published Date : Dec 01, 2011
Study Type : Human: Case Report
Additional Links
Substances : Calcium, Vitamin D
Diseases : Celiac Disease, Osteomalacia, Osteoporosis
Therapeutic Actions : Dietary Modification: Wheat/Gluten Free
Problem Substances : Gluten
[+]

High dose vitamin D may have a therapeutic role in certain cases of chronic pain associated with sickle cell anemia. Oct 01, 2011

Pubmed Data : J Pediatr Hematol Oncol. 2011 Oct ;33(7):549-51. PMID: 21941148
Article Published Date : Oct 01, 2011
Study Type : Human: Case Report
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis, Sickle Cell Anemia, Vitamin D Deficiency
[+]

This case report describes a case of PPI-induced thrombocytopenia.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Case Rep Gastrointest Med. 2018 ;2018:4294805. Epub 2018 Apr 30. PMID: 29854491
Article Published Date : Dec 31, 2017
Study Type : Human: Case Report, Review
Additional Links
Diseases : Drug-Induced Nutrient Depletion: Vitamin B-12, Osteoporosis, Thrombocytopenia
Additional Keywords : Risk Factors
Problem Substances : Proton-Pump Inhibitors
[+]

Oral administration of melatonin contained in drinking water increased bone strength in naturally aged mice.Aug 31, 2020

Pubmed Data : Acta Histochem. 2020 Sep ;122(6):151596. Epub 2020 Jul 18. PMID: 32778234
Article Published Date : Aug 31, 2020
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Poncirin prevents bone loss in glucocorticoid-induced osteoporosis in vivo and in vitro.Aug 31, 2012

Pubmed Data : J Bone Miner Metab. 2012 Sep ;30(5):509-16. Epub 2012 Mar 13. PMID: 22407507
Article Published Date : Aug 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

The opposite effects of Antarctic krill oil and arachidonic acid-rich oil on bone resorption in ovariectomized mice.Aug 18, 2020

Pubmed Data : Food Funct. 2020 Aug 19 ;11(8):7048-7060. PMID: 32813003
Article Published Date : Aug 18, 2020
Study Type : Animal Study
Additional Links
Substances : Krill
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

"Clove (Syzygium aromaticum Linn) extract rich in eugenol and eugenol derivatives shows bone-preserving efficacy."Mar 01, 2012

Pubmed Data : Nat Prod Res. 2012 Mar ;26(6):500-9. Epub 2011 Jun 28. PMID: 21711176
Article Published Date : Mar 01, 2012
Study Type : Animal Study
Additional Links
Substances : Clove
Diseases : Osteoporosis, Osteoporosis: hypogonadal , Ovariectomy Associated Adverse Changes
[+]

18β-glycyrrhetinic acid is a promising novel candidate in the treatment of osteoclast-related diseases such as postmenopausal osteoporosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:647. Epub 2018 Jun 20. PMID: 29973878
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : 18β-Glycyrrhetinic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside can be considered as a potential therapeutic for the treatment of postmenopausal osteoporosis.Aug 27, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Aug 28 ;19(9). Epub 2018 Aug 28. PMID: 30154383
Article Published Date : Aug 27, 2018
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Pharmacological Actions : Chondroprotective, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
[+]

A mineral-rich extract from the red marine algae Lithothamnion calcareum preserves bone structure and function in female mice on a Western-style diet.Apr 01, 2010

Pubmed Data : Calcif Tissue Int. 2010 Apr;86(4):313-24. Epub 2010 Feb 24. PMID: 20180099
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Substances : Red Marine Algae
Diseases : Bone Fractures, Hip Fracture, Osteoporosis, Western-Style Diet Induced Toxicity
Anti Therapeutic Actions : Western Diet
[+]

A soy extract may be more effective than purified genistein in improving tibial trabecular bone quality in ovariectomized mice. Jul 01, 2009

Pubmed Data : 1: Mol Pharm. 2009 Jul-Aug;6(4):1152-9. PMID: 19793844
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Genistein, Soy
Diseases : Osteoporosis
Additional Keywords : Plant Extracts, The Whole is Superior to the Monochemical Part
[+]

A western-style diet reduces bone mass and biomechanical bone strength to a greater extent in male compared with female rats during development.Sep 01, 2003

Pubmed Data : Br J Nutr. 2003 Sep;90(3):589-95. PMID: 13129465
Article Published Date : Sep 01, 2003
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Anti Therapeutic Actions : Western Diet
[+]

Acetyl-11-keto-β-boswellic acid showed good antiosteoporotic activity.Oct 17, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Oct 18 ;12(10). Epub 2020 Oct 18. PMID: 33081068
Article Published Date : Oct 17, 2020
Study Type : Animal Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Adlay may be a helpful healthy food for osteoporosis prevention.Mar 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2013 Apr ;3(2):134-8. PMID: 24716168
Article Published Date : Mar 31, 2013
Study Type : Animal Study
Additional Links
Substances : Adlay
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

All these results strongly indicate that puerarin exerts its anti-osteoprotic action independently of the ER-mediated pathway.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2012 ;58(3):202-9. PMID: 22878391
Article Published Date : Dec 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Allicin reversed the process of frailty in aging male Fischer 344 rats with osteoporosis.Sep 20, 2019

Pubmed Data : J Gerontol A Biol Sci Med Sci. 2019 Sep 21. Epub 2019 Sep 21. PMID: 31541608
Article Published Date : Sep 20, 2019
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Anabolic therapy with Equisetum arvense along with bone mineralising nutrients in ovariectomized rat model of osteoporosis.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2016 May-Jun;48(3):312-5. PMID: 27298503
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Horsetail
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Natural Substances Versus Drugs
[+]

Analysis of anti-osteoporosis function of chlorogenic acid by gene microarray profiling in ovariectomy rat model.Jan 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2018 08 31 ;38(4). Epub 2018 Aug 31. PMID: 30054432
Article Published Date : Jan 30, 2018
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Anti-climacterium effects of pomegranate concentrated solutions in ovariectomized ddY mice.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2017 Apr ;13(4):1249-1266. Epub 2017 Feb 8. PMID: 28413464
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Hepatic Steatosis, Hyperlipidemia, Obesity, Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes, Risk Reduction
[+]

Anti-inflammatory and anti-osteoporotic potential of Lactobacillus plantarum A41 and L. fermentum SRK414 as probiotics.Aug 01, 2019

Pubmed Data : Probiotics Antimicrob Proteins. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31372901
Article Published Date : Aug 01, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Osteoprotective
[+]

Anti-osteoporotic effects of polysaccharides isolated from persimmon leaves via osteoclastogenesis inhibition.Jul 12, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jul 13 ;10(7). Epub 2018 Jul 13. PMID: 30011853
Article Published Date : Jul 12, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Persimmon
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts, Polysaccharides
[+]

Anti-osteoporotic effects of Salvia miltiorrhiza Bunge EtOH extract both in ovariectomized and naturally menopausal mouse models.Apr 17, 2020

Pubmed Data : J Ethnopharmacol. 2020 Apr 18 ;258:112874. Epub 2020 Apr 18. PMID: 32311485
Article Published Date : Apr 17, 2020
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Antrodia camphorata extract could promote osteogenesis and prevent bone loss.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:2617868. Epub 2016 Apr 10. PMID: 27143981
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Antrodia camphorata
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : Bone Regeneration, Plant Extracts
[+]

Aqueous extracts of parsley, basil and chicory showed bone protection against glucocorticoid-induced osteoporosis in rats.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 ;16(1):165. Epub 2016 Jun 2. PMID: 27255519
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Basil, Chicory, Parsley
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Bone Density Conservation Agents
Additional Keywords : Plant Extracts
[+]

Artemisia annua extract prevents ovariectomy-induced bone loss.Dec 10, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Dec 11 ;7(1):17332. Epub 2017 Dec 11. PMID: 29230013
Article Published Date : Dec 10, 2017
Study Type : Animal Study
Additional Links
Substances : Mugwort
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Ascorbic acid administration in the Akr1A1 knockout mice led to controllable osteoporosis.Jan 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Jan 31 ;8(5):7357-7369. PMID: 28060768
Article Published Date : Jan 30, 2017
Study Type : Transgenic Animal Study
Additional Links
Substances : Vitamin C
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Ashwaganda markedly prevents bone changes in ovarectomized rats.Feb 01, 2007

Pubmed Data : Phytomedicine. 2007 Feb;14(2-3):136-42. Epub 2006 May 18. PMID: 16597369
Article Published Date : Feb 01, 2007
Study Type : Animal Study
Additional Links
Substances : Ashwagandha
Diseases : Osteoporosis
[+]

Asiatic acid inhibits OVX-induced osteoporosis and osteoclastogenesis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:331. Epub 2020 Mar 27. PMID: 32292339
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Asiatic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Asiatic acid may be a potential anti-resorptive agent for postmenopausal osteoporosis.Aug 20, 2019

Pubmed Data : Calcif Tissue Int. 2019 Aug 21. Epub 2019 Aug 21. PMID: 31435709
Article Published Date : Aug 20, 2019
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid
Diseases : Osteoporosis, Postmenopausal Disorders
Pharmacological Actions : Osteoprotective
[+]

Astaxanthin improves osteopenia caused by aldehyde-stress resulting from Aldh2 mutation due to impaired osteoblastogenesis. Jun 17, 2020

Pubmed Data : Biochem Biophys Res Commun. 2020 Jun 18 ;527(1):270-275. Epub 2020 May 4. PMID: 32446379
Article Published Date : Jun 17, 2020
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Osteopenia, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL‐induced osteoclastogenesis.Jan 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 12 ;23(12):8355-8368. Epub 2019 Oct 11. PMID: 31603626
Article Published Date : Jan 11, 2019
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Astragalin promotes osteoblastic differentiation in MC3T3-E1 cells and bone formation in vivo.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Endocrinol (Lausanne). 2019 ;10:228. Epub 2019 Apr 16. PMID: 31040823
Article Published Date : Dec 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Beneficial effects of paeoniflorin on osteoporosis induced by high-carbohydrate, high-fat diet-associated hyperlipidemia.Jan 14, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 04 15 ;498(4):981-987. Epub 2018 Mar 17. PMID: 29550473
Article Published Date : Jan 14, 2018
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : High Fat Diet, Hyperlipidemia, Osteoporosis
Pharmacological Actions : Hypolipidemic, Osteoprotective
[+]

Berberine alleviates oxidative stress in rats with osteoporosis.Oct 21, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bosn J Basic Med Sci. 2017 Oct 22. Epub 2017 Oct 22. PMID: 29055350
Article Published Date : Oct 21, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Berberine ameliorates periodontal bone loss by regulating gut microbiota.Sep 09, 2018

Pubmed Data : J Dent Res. 2018 Sep 10:22034518797275. Epub 2018 Sep 10. PMID: 30199654
Article Published Date : Sep 09, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Osteoporosis, Periodontitis, Postmenopausal Disorders
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Berberine may be a potential treatment for controlling bone loss in diabetic osteoporosis.Sep 13, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep 14 ;108:280-287. Epub 2018 Sep 14. PMID: 30223099
Article Published Date : Sep 13, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Diabetic Complications, Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Bergapten exerts inhibitory effects on diabetes-related osteoporosis.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2016 Dec ;38(6):1661-1672. Epub 2016 Nov 2. PMID: 27840967
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Bergamot orange
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Beta-caryophyllene may be used as a therapeutic agent for the prevention and treatment of osteoporosis.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Dec ;12(6):3602-3606. Epub 2016 Oct 18. PMID: 28105093
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Beta-Caryophyllene, Osteoporosis, Osteoprotective
[+]

Bisphosphonates do not improve bone material characteristics such as tissue strength, elastic modulus, and cortical toughness in an animal model of osteoporosis. Nov 26, 2009

Pubmed Data : Bone. 2009 Nov 26. PMID: 19931661
Article Published Date : Nov 26, 2009
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Bisphosphonates
[+]

Black raspberry extracts may benefit osteoporotic patients with prostatic disease by simultaneously altering the activation of osteoblasts and osteoclasts.May 31, 2015

Pubmed Data : Aging Male. 2015 Jun ;18(2):124-32. Epub 2014 Aug 19. PMID: 25136745
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Raspberry
Diseases : Aging, Osteoporosis
Additional Keywords : Cannabinoid Receptors, Plant Extracts
[+]

Black raspberry vinegar could be an effective natural alternative for the prevention of postmenopausal osteoporosis.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 ;21(2). Epub 2016 Jan 26. PMID: 26821009
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Raspberry
Diseases : Osteoporosis, Ovariectomy Associated Adverse Changes
Pharmacological Actions : Prophylactic Agents
Additional Keywords : Risk Reduction
[+]

Black Tea significantly inhibits bone loss in ovariectomized rats.Jan 01, 2004

Pubmed Data : Asia Pac J Clin Nutr. 2004;13(2):210-6. PMID: 15228990
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Black Tea
Diseases : Osteoporosis
[+]

Blueberry diets in early life prevent senescence of osteoblasts and bone loss in ovariectomized adult female rats.Jan 01, 2011

Pubmed Data : PLoS One. 2011 ;6(9):e24486. Epub 2011 Sep 2. PMID: 21912699
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Blueberry
Diseases : Aging, Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
[+]

Boron stimulates bone formation, inhibits bone resorption, resulting in a therapeutic effect against osteoporosis.Dec 01, 2006

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2006 Dec;26(12):1785-8. PMID: 17259120
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Osteoporosis
[+]

Citrus juice positively affects serum antioxidant status and bone strength.May 01, 2006

Pubmed Data : Nutrition. 2006 May;22(5):559-63. Epub 2006 Feb 10. PMID: 16472977
Article Published Date : May 01, 2006
Study Type : Animal Study
Additional Links
Substances : Orange
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants
[+]

Co-administrated puerarin and zinc can partially reverse OVX-induced bone loss.Nov 30, 2016

Pubmed Data : Life Sci. 2016 Dec 1 ;166:20-26. Epub 2016 Sep 30. PMID: 27697446
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Puerarin, Zinc
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : bone loss, Osteoporosis, Ovariectomy-Induced Changes, Puerarin, zinc
[+]

Consumption of vitamin D2 enhanced mushrooms is associated with improved bone health.Jun 30, 2015

Pubmed Data : J Nutr Biochem. 2015 Jul ;26(7):696-703. Epub 2015 Mar 5. PMID: 25792284
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Mushrooms: All
Diseases : Osteoporosis
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

CoQ10 stimulates the proliferation and differentiation of BMSCs and is effective for the treatment of OVX induced osteoporosis.Dec 31, 2017

Pubmed Data : Mol Med Rep. 2018 Jan ;17(1):400-407. Epub 2017 Oct 26. PMID: 29115467
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Crocin attenuates metabolic syndrome-induced osteoporosis.Jun 30, 2019

Pubmed Data : J Food Biochem. 2019 Jul ;43(7):e12895. Epub 2019 May 15. PMID: 31353703
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Metabolic Syndrome X, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Cumambrin A prevents OVX-induced osteoporosis.Dec 31, 2018

Pubmed Data : FASEB J. 2019 06 ;33(6):6726-6735. Epub 2019 Feb 26. PMID: 30807230
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Indicum
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
Additional Keywords : Ovariectomy-Induced Changes
[+]

Cumin extract reverses bone loss in ovariectomized rats as well as estradiol.Sep 29, 2008

Pubmed Data : Exp Biol Med (Maywood). 2008 Sep 29. PMID: 18824723
Article Published Date : Sep 29, 2008
Study Type : Animal Study
Additional Links
Substances : Cumin
Diseases : Osteoporosis
Additional Keywords : Natural Substances Versus Drugs
[+]

Curcumin alleviated HLS-induced reduction of bone mineral density in tibiae and preserved bone structure in tibiae and mechanical strength in femurs.May 11, 2015

Pubmed Data : Osteoporos Int. 2015 May 12. Epub 2015 May 12. PMID: 25963235
Article Published Date : May 11, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Vitamin D Receptor (VDR) Modulator
Additional Keywords : Microgravity Induced Bone Loss
[+]

Curcumin improves bone microarchitecture and enhances mineral density in transgenic mice.Jan 15, 2011

Pubmed Data : Phytomedicine. 2011 Jan 15;18(2-3):205-13. Epub 2010 Jul 16. PMID: 20637579
Article Published Date : Jan 15, 2011
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Bone Fractures, Osteopenia, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin may be a potential therapeutic agent for the treatment of glucocorticoid induced osteoporosis.Dec 10, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2015 Dec 11. Epub 2015 Dec 11. PMID: 26677102
Article Published Date : Dec 10, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Osteoporosis
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
Problem Substances : Dexamethasone
[+]

Curcumin may be a promising drug for prevention and treatment of glucocorticoid-induced osteoporosis.Oct 29, 2015

Pubmed Data : Clin Exp Pharmacol Physiol. 2015 Oct 30. Epub 2015 Oct 30. PMID: 26515751
Article Published Date : Oct 29, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Osteoporosis
[+]

Curcumin produces beneficial changes in bone turnover and increases in bone strength using the ovariectomized mature rat model of postmenopausal osteoporosis.Dec 01, 2008

Pubmed Data : Phytomedicine. 2008 Dec;15(12):1069-78. Epub 2008 Aug 6. PMID: 18693096
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Osteoporosis, Osteoporosis: Age-Related, Postmenopausal Disorders
[+]

DHA exerts an anti-osteoclastogenic effect by suppressing the proliferation and differentiation of bone marrow-derived macrophages.Nov 08, 2016

Pubmed Data : Cell Signal. 2016 Nov 9 ;29:226-232. Epub 2016 Aug 9. PMID: 27836739
Article Published Date : Nov 08, 2016
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Osteoporosis, Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective
[+]

DHA inhibits osteoclast activation and bone resorption. Jan 01, 2008

Pubmed Data : J Cell Physiol. 2008 Jan;214(1):201-9. PMID: 17929247
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Osteoporosis
[+]

Dietary cordycepin can prevent bone loss caused by estrogen deficiency.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:423869. Epub 2015 Mar 22. PMID: 25874211
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Osteoporosis, Oxidative Stress
Pharmacological Actions : Antioxidants, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Dioscorea spongiosa has profound antiosteoporotic effects. Apr 01, 2004

Pubmed Data : Biol Pharm Bull. 2004 Apr;27(4):583-6. PMID: 15056872
Article Published Date : Apr 01, 2004
Study Type : Animal Study
Additional Links
Substances : Dioscorea spongiosa
Diseases : Osteoporosis
[+]

Diosgenin prevents bone loss on retinoic acid-induced osteoporosis.Jul 31, 2016

Pubmed Data : Ir J Med Sci. 2016 Aug ;185(3):581-7. Epub 2015 Jun 19. PMID: 26089290
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Diosgenin protects against alveolar bone loss in ovariectomized rats via regulating long non-coding RNAs.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Nov ;16(5):3939-3950. Epub 2018 Sep 3. PMID: 30344672
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : MicroRNA modulator, Osteoprotective
[+]

Dried and free flowing granules of Spinacia oleracea accelerate bone regeneration and alleviate postmenopausal osteoporosis.Dec 31, 2016

Pubmed Data : Menopause. 2017 06 ;24(6):686-698. PMID: 28118295
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Spinach
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration, Ovariectomy-Induced Changes, Plant Extracts
[+]

Effects of Nigella sativa and human parathyroid hormone on bone mass and strength in diabetic rats.May 31, 2007

Pubmed Data : Biol Trace Elem Res. 2007 Jun ;116(3):321-8. PMID: 17709912
Article Published Date : May 31, 2007
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

EGCG decreases ovariectomy-induced bone loss via inhibition of osteoclasts.Mar 21, 2012

Pubmed Data : Calcif Tissue Int. 2012 Mar 21. Epub 2012 Mar 21. PMID: 22434366
Article Published Date : Mar 21, 2012
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
[+]

EGCG reversed GIO in rats by protecting osteoblasts by activating the Nrf2 signaling pathway.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:447. Epub 2018 May 9. PMID: 29867459
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective
[+]

Electroacupuncture prevents ovariectomy-induced osteoporosis in rats.Mar 01, 2012

Pubmed Data : Acupunct Med. 2012 Mar ;30(1):37-43. PMID: 22378584
Article Published Date : Mar 01, 2012
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis, Ovariectomy Associated Adverse Changes
Therapeutic Actions : Electroacupuncture
Additional Keywords : Ovariectomy-Induced Changes
[+]

Emodin suppresses IBD-induced osteoporosis by inhibiting osteoclast formation.Jan 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31934719
Article Published Date : Jan 13, 2020
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Inflammatory Bowel Diseases, Osteoporosis
Pharmacological Actions : Gastrointestinal Agents, Osteoprotective
[+]

Emodin suppresses the cadmium induced osteoporosis by inhibiting osteoclast formation.Aug 31, 2017

Pubmed Data : Environ Toxicol Pharmacol. 2017 Sep ;54:162-168. Epub 2017 Jul 18. PMID: 28738286
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Cadmium Poisoning , Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Evaluation of anti-osteoporotic activity of butanolic fraction from Passiflora foetida in ovariectomy-induced bone loss in mice.Mar 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Apr ;88:804-813. Epub 2017 Feb 1. PMID: 28160755
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Passion Flower
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Exercise may ameliorate the detrimental side effects of high vitamin D supplementation on muscle function in mice.Feb 19, 2020

Pubmed Data : J Bone Miner Res. 2020 Feb 20. Epub 2020 Feb 20. PMID: 32078180
Article Published Date : Feb 19, 2020
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Osteoporosis
Therapeutic Actions : Exercise
Additional Keywords : Risk Reduction
[+]

Fennel supresses the ovariectomy-induced increase in bone turnover, indicating it may prevent postmenopausal osteoporosis.Jun 01, 2012

Pubmed Data : Int J Mol Med. 2012 Jun ;29(6):1053-9. Epub 2012 Mar 23. PMID: 22447109
Article Published Date : Jun 01, 2012
Study Type : Animal Study
Additional Links
Substances : Fennel
Diseases : Aging, Osteoporosis, Ovariectomy Associated Adverse Changes, Postmenopausal Disorders
Additional Keywords : Ovariectomy-Induced Changes
[+]

Fermentation improves calcium bioavailability in Moringa oleifera leaves and prevents bone loss in calcium-deficient rats.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Nutr. 2020 Jul ;8(7):3692-3703. Epub 2020 May 25. PMID: 32724632
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Moringa oleifera
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic
[+]

Fermented rooibos may have a beneficial effect on bone health.May 22, 2018

Pubmed Data : Food Funct. 2018 May 23. Epub 2018 May 23. PMID: 29790498
Article Published Date : May 22, 2018
Study Type : Animal Study
Additional Links
Substances : Rooibos
Diseases : Bone Diseases, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective
[+]

Ferulic acid exhibited protective effects against osteoporosis.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Dec ;120:109205. Epub 2019 Oct 18. PMID: 31634777
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Ferulic acid
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, SIRT1 Activator
[+]

Formononetin enhances bone regeneration in a mouse model of cortical bone defect.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Nutr. 2017 Jun ;117(11):1511-1522. Epub 2017 Jul 10. PMID: 28689509
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Formononetin, Isoflavones
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Bone Regeneration
[+]

Ganoderma lucidum immune modulator protein rLZ-8 could prevent and reverse bone loss in glucocorticoids-induced osteoporosis model. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:731. Epub 2020 May 19. PMID: 32508652
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Gastrodin may be useful in the prevention and treatment of osteoporosis.Mar 31, 2015

Pubmed Data : Bone. 2015 Apr ;73:132-44. Epub 2014 Dec 29. PMID: 25554600
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Osteoporosis
Pharmacological Actions : Interleukin-6 Downregulation
Additional Keywords : Ovariectomy-Induced Changes
[+]

Gastrodin was able to prevent or delay dexamethasone induced osteoporosis.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2018 Apr ;41(4):2059-2069. Epub 2018 Jan 23. PMID: 29393365
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Nrf2 activation, Osteoprotective
Problem Substances : Dexamethasone
[+]

Genistein and equol positively effect bone quality and quantity in osteoporotic mice. Mar 01, 2002

Pubmed Data : J Vet Med Sci. 2002 Mar;64(3):227-35. PMID: 20036112
Article Published Date : Mar 01, 2002
Study Type : Animal Study
Additional Links
Substances : Equol, Genistein
Diseases : Osteoporosis
[+]

Genistein is superior to the bone drugs alendronate, raloxifene and estradiol in osteoporotic, ovariectomized rats. Nov 01, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2008 Nov;155(6):896-905. Epub 2008 Aug 11. PMID: 18695641
Article Published Date : Nov 01, 2008
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Bone Fractures, Osteopenia, Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes, Superiority of Natural Substances versus Drugs
[+]

Genistein preserved the biomechanical quality of the trabecular bone regardless of the microstructure and bone mineral density. Jan 01, 2008

Pubmed Data : J Bone Miner Metab. 2008;26(4):342-9. Epub 2008 Jul 4. PMID: 18600400
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Osteoporosis
Additional Keywords : Bone Quality
[+]

Ginsenoside Rg3 attenuates aluminum-induced osteoporosis.Mar 15, 2020

Pubmed Data : Biol Trace Elem Res. 2020 Mar 16. Epub 2020 Mar 16. PMID: 32173789
Article Published Date : Mar 15, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Aluminum Toxicity , Osteoporosis
Pharmacological Actions : Antioxidants
Problem Substances : Aluminum
[+]

Grapefruit juice showed a beneficial anti-osteoporotic effect against prednisolone-induced osteoporosis.May 29, 2019

Pubmed Data : Cytotechnology. 2019 May 30. Epub 2019 May 30. PMID: 31147813
Article Published Date : May 29, 2019
Study Type : Animal Study
Additional Links
Substances : Grapefruit
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Green tea polyphenols mitigate bone loss of female rats in a chronic inflammation-induced bone loss model.Dec 03, 2009

Pubmed Data : J Nutr Biochem. 2009 Dec 3. Epub 2009 Dec 3. PMID: 19962296
Article Published Date : Dec 03, 2009
Study Type : Animal Study
Additional Links
Substances : Green Tea
Diseases : Osteoporosis, Osteoporosis: Inflammation Induced
[+]

Green tea polyphenols mitigate deterioration of bone microarchitecture in middle-aged female rats.Apr 01, 2009

Pubmed Data : Bone. 2009 Apr;44(4):684-90. Epub 2008 Dec 11. PMID: 19118658
Article Published Date : Apr 01, 2009
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Polyphenols, Tea
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants
Additional Keywords : Bone Quality
[+]

Green tea supplementation benefits body composition and improves bone properties in obese female rats fed with high-fat diet and caloric restricted diet.Dec 01, 2015

Pubmed Data : Nutr Res. 2015 Dec ;35(12):1095-105. Epub 2015 Oct 5. PMID: 26525915
Article Published Date : Dec 01, 2015
Study Type : Animal Study
Additional Links
Substances : Polyphenols
Diseases : Adiponectin: Low Levels, Female, Obesity, Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Harmine enhances type H vessel formation and prevents bone loss in ovariectomized mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2018 ;8(9):2435-2446. Epub 2018 Mar 28. PMID: 29721090
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Psychedelics:All
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Harmine inhibits osteoclast differentiation and bone resorption in vitro and in vivo.Jan 14, 2011

Pubmed Data : Eur J Pharmacol. 2011 Jan 15 ;650(2-3):511-8. Epub 2010 Nov 1. PMID: 21047508
Article Published Date : Jan 14, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Psychedelics:All
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Harpagide has a potential for prevention of bone loss in ovariectomized mice.Feb 16, 2016

Pubmed Data : J Ethnopharmacol. 2016 Feb 17 ;179:66-75. Epub 2015 Dec 19. PMID: 26712566
Article Published Date : Feb 16, 2016
Study Type : Animal Study
Additional Links
Substances : Devils Claw
Diseases : Osteoporosis
Pharmacological Actions : Bone Density Conservation Agents
Additional Keywords : Ovariectomy-Induced Changes
[+]

Hesperetin prevents bone resorption by inhibiting RANKL-induced osteoclastogenesis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1028. Epub 2018 Sep 11. PMID: 30254586
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Hesperidin could be considered to be a beneficial treatment for preventing diabetic osteoporosis in growing age.Jan 25, 2017

Pubmed Data : Exp Toxicol Pathol. 2017 Jan 26. Epub 2017 Jan 26. PMID: 28132802
Article Published Date : Jan 25, 2017
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Diabetes Mellitus: Type 1, Osteoporosis
Pharmacological Actions : Osteoprotective , Prophylactic Agents
Additional Keywords : Risk Reduction
[+]

Hesperidin has therapeutic effects in the formation and maintenance of bone mass and strength.Mar 01, 2008

Pubmed Data : J Appl Physiol. 2008 Mar;104(3):648-54. Epub 2008 Jan 3. PMID: 18174393
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Osteoporosis
Additional Keywords : Bone Quality
[+]

High-dose diosgenin reduces bone loss in ovariectomized rats via attenuation of the RANKL/OPG ratio.Sep 24, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2014 Sep 25 ;15(9):17130-47. Epub 2014 Sep 25. PMID: 25257532
Article Published Date : Sep 24, 2014
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Hu Zhang (resveratrol) has positive effect on bone loss in the ovariectomized rat model. Mar 01, 2005

Pubmed Data : J Med Food. 2005 Spring;8(1):14-9. PMID: 15857203
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Substances : Hu Zhang (Polygonum cuspidatum), Resveratrol
Diseases : Osteoporosis
[+]

Humulus lupulus L. extract may protect against bone loss, and have potentials in the treatment of osteoporosis.Mar 26, 2019

Pubmed Data : Chin J Integr Med. 2019 Mar 27. Epub 2019 Mar 27. PMID: 30919241
Article Published Date : Mar 26, 2019
Study Type : Animal Study
Additional Links
Substances : Hops
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Inhibition of osteoclastogenesis and bone resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 Dec 1 ;5:17605. Epub 2015 Dec 1. PMID: 26620037
Article Published Date : Nov 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Xanthohumol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Isoquercitrin may be considered a safer alternative for managing osteoporosis.Dec 14, 2019

Pubmed Data : Eur J Pharmacol. 2019 Dec 15 ;865:172785. Epub 2019 Nov 9. PMID: 31712059
Article Published Date : Dec 14, 2019
Study Type : Animal Study
Additional Links
Substances : Isoquercitrin
Diseases : Osteoporosis
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor, Osteoprotective
[+]

Kaempferol promotes bone formation in part via the mTOR signaling pathway.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Dec ;20(6):5197-5207. Epub 2019 Oct 16. PMID: 31638215
Article Published Date : Nov 30, 2019
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic
[+]

Kefir has a protective effect against bone loss, deterioration of trabecular microarchitecture, and biomechanical dysfunction.Jan 31, 2015

Pubmed Data : Osteoporos Int. 2015 Feb ;26(2):589-99. Epub 2014 Oct 3. PMID: 25278298
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Kefir, Milk: Fermented
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic
Additional Keywords : Significant Treatment Outcome
[+]

Kudzu completely prevents ovariectomized bone loss in mice, indicating it may be an alternative to hormone replacement therapy in the prevention of osteoporosis in postmenopausal women.Jan 01, 2003

Pubmed Data : J Bone Miner Metab. 2003;21(5):268-75. PMID: 12928827
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Kudzu
Diseases : Osteoporosis
[+]

L-arginine supplementation normalizes bone turnover and preserves bone mass in streptozotocin-induced diabetic rats.Jun 01, 2009

Pubmed Data : J Endocrinol Invest. 2009 Jun;32(6):546-51. Epub 2009 May 5. PMID: 19494718
Article Published Date : Jun 01, 2009
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Diabetes Mellitus: Type 1: Prevention, Osteopenia, Osteoporosis
[+]

L. sativum ameliorates ovariectomy-induced bone injury in rats.Jul 12, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Jul 13 ;12(7). Epub 2020 Jul 13. PMID: 32668691
Article Published Date : Jul 12, 2020
Study Type : Animal Study
Additional Links
Substances : Garden Cress (Lepidium sativum)
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Lactobacillus plantarum NK3 and Bifidobacterium longum NK49 may simultaneously alleviate bacterial vaginosis and osteoporosis.Sep 30, 2019

Pubmed Data : J Med Food. 2019 Oct ;22(10):1022-1031. Epub 2019 Aug 5. PMID: 31381476
Article Published Date : Sep 30, 2019
Study Type : Animal Study
Additional Links
Substances : Bifidobacterium Longum , Kimchi, Lactobacillus plantarum
Diseases : Bacterial Vaginosis, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Osteoprotective , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactoferrin preserves bone mass and micoarchitechiture in ovariectomized rats. May 01, 2009

Pubmed Data : J Nutr. 2009 May;139(5):958-64. Epub 2009 Mar 25. PMID: 19321577
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Lactoferrin
Diseases : Osteoporosis
[+]

Long-term dietary intake of chia seed is associated with increased bone mineral content and improved hepatic and intestinal morphology.Jul 18, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2018 Jul 19 ;10(7). Epub 2018 Jul 19. PMID: 30029467
Article Published Date : Jul 18, 2018
Study Type : Animal Study
Additional Links
Substances : Chia
Diseases : Osteoporosis
Pharmacological Actions : Hepatoprotective, Hypolipidemic, Osteoprotective
[+]

Long-term electroacupuncture stimulation prevents osteoporosis in ovariectomised osteopaenic rats.Apr 05, 2018

Pubmed Data : Acupunct Med. 2018 Apr 6. Epub 2018 Apr 6. PMID: 29625972
Article Published Date : Apr 05, 2018
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Osteoprotective
[+]

Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Animal Model Exp Med. 2019 Mar ;2(1):51-57. Epub 2019 Feb 21. PMID: 31016287
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Therapeutic Actions : Laser Treatment: Low-Level
Additional Keywords : Ovariectomy-Induced Changes
[+]

Low‑molecular weight fucoidan inhibits the differentiation of osteoclasts and reduces osteoporosis in ovariectomized rats.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Feb ;15(2):890-898. Epub 2016 Dec 20. PMID: 28000877
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Lysine may play a key role in preventing and treating osteoporosis.Jan 01, 1993

Pubmed Data : Nutrition. 1993 Jan-Feb;9(1):71-2. PMID: 8467115
Article Published Date : Jan 01, 1993
Study Type : Animal Study
Additional Links
Substances : Lysine
Diseases : Osteoporosis
[+]

Maca protects against estrogen deficient bone loss in an animal model of ovariectomy induced osteoporosis. Apr 21, 2006

Pubmed Data : J Ethnopharmacol. 2006 Apr 21;105(1-2):274-9. Epub 2006 Feb 8. PMID: 16466876
Article Published Date : Apr 21, 2006
Study Type : Animal Study
Additional Links
Substances : Maca
Diseases : Osteoporosis
[+]

magnolol is a promising agent for the treatment of osteoporosis and associated disorders.Feb 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2019 Feb 18. Epub 2019 Feb 18. PMID: 30816431
Article Published Date : Feb 17, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Magnolol
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Manganese supplementation improves mineral density in rats. Jul 01, 2008

Pubmed Data : Biol Trace Elem Res. 2008 Jul;124(1):28-34. Epub 2008 Mar 11. PMID: 18330520
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Manganese
Diseases : Osteoporosis
[+]

Melatonin restores the osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells.Oct 23, 2019

Pubmed Data : Free Radic Biol Med. 2019 Oct 24. Epub 2019 Oct 24. PMID: 31669348
Article Published Date : Oct 23, 2019
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants
Additional Keywords : Mesenchymal Stem Cells
[+]

Melatonin treatment is an efficient and practical strategy to improve in vitro expansion of BMMSCs for tissue engineering and cytotherapy.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2016 ;6(11):1899-917. Epub 2016 Aug 8. PMID: 27570559
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Regenerative
Additional Keywords : Mesenchymal Stem Cells
[+]

Menaquinone-7, a form of vitamin K2, has a stimulatory effect on bone formation in the femoral tissues of elderly female rats in vitro.Dec 01, 2002

Pubmed Data : Int J Mol Med. 2002 Dec;10(6):729-33. PMID: 12429999
Article Published Date : Dec 01, 2002
Study Type : Animal Study
Additional Links
Substances : Genistein, Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Aging, Osteopenia, Osteoporosis
[+]

Menaquinone-7, a form of vitamin K2, may prevent age-related bone loss. Jan 01, 2004

Pubmed Data : Biofactors. 2004;22(1-4):5-19. PMID: 15630245
Article Published Date : Jan 01, 2004
Study Type : Animal Study
Additional Links
Substances : Vitamin K, Vitamin K2: Menaquinone-7
Diseases : Aging, Osteoporosis
[+]

Montmorency tart cherry protects against age-related bone loss in female C57BL/6 mice.Oct 29, 2018

Pubmed Data : Eur J Nutr. 2018 Oct 30. Epub 2018 Oct 30. PMID: 30377814
Article Published Date : Oct 29, 2018
Study Type : Animal Study
Additional Links
Substances : Tart Cherry
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Mushroom extracts decrease bone resorption and improve bone formation.Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(7):559-69. PMID: 27649725
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Maitake Mushroom, Oyster Mushroom, Shiitake Mushroom
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic, Osteoprotective
Additional Keywords : Plant Extracts
[+]

Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.Jun 04, 2018

Pubmed Data : Life Sci. 2018 Jun 5. Epub 2018 Jun 5. PMID: 29883721
Article Published Date : Jun 04, 2018
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Myricetin may be a potential agent for the treatment of periodontitis and osteoporosis.Mar 21, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 Mar 22 ;17(3):422. Epub 2016 Mar 22. PMID: 27011174
Article Published Date : Mar 21, 2016
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Osteoporosis, Periodontitis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

N-acetylcysteine prevents orchiectomy-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(7):4337-4347. Epub 2019 Jul 15. PMID: 31396339
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine)
Diseases : Osteoporosis
Pharmacological Actions : Antioxidants, Osteoprotective
[+]

Naringin attentuates retinoic acid-induced osteoporosis in an animal model. Jan 01, 2007

Pubmed Data : Am J Chin Med. 2007;35(4):663-7. PMID: 17708632
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Osteoporosis
[+]

Naringin promotes fracture healing through stimulation of angiogenesis.Jan 04, 2017

Pubmed Data : Chem Biol Interact. 2017 Jan 5 ;261:11-17. Epub 2016 Nov 8. PMID: 27833010
Article Published Date : Jan 04, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Bone Fractures, Osteoporosis
Pharmacological Actions : Angiogenesis Inducing Agents
[+]

Nigella Sativa reverses osteoporosis in ovariectomized rats.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2014 ;14(1):22. Epub 2014 Jan 14. PMID: 24422662
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Menopausal Syndrome, Osteopenia, Osteoporosis, Ovarian Failure
Additional Keywords : Ovariectomy-Induced Changes
[+]

Nigella sativa seed extract demonstrated incredibly positive effects on enhanced bone healing in this experimental osteoporotic model.Aug 09, 2016

Pubmed Data : J Craniofac Surg. 2016 Aug 10. Epub 2016 Aug 10. PMID: 27513784
Article Published Date : Aug 09, 2016
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
[+]

Nobiletin clearly restored the alveolar bone mass in a mouse experimental model for periodontitis by inhibiting LPS-induced bone resorption.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2012 ;119(4):390-4. Epub 2012 Jul 31. PMID: 22850615
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Nobiletin , Tangeretin
Diseases : Lipopolysaccharide-Induced Toxicity, Osteoporosis, Periodontitis
Additional Keywords : Significant Treatment Outcome
[+]

Nobiletin-loaded micelles reduce ovariectomy-induced bone loss by suppressing osteoclastogenesis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2019 ;14:7839-7849. Epub 2019 Sep 26. PMID: 31576127
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Noni fruit puree compares favorably in analgesic and anti-inflammatory activity to tramadol and hydrocortisone, respectively, in an animal model of arthritis.Jun 22, 2009

Pubmed Data : Phytother Res. 2009 Jun 22. PMID: 19548275
Article Published Date : Jun 22, 2009
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Arthritis, Inflammation, Osteoporosis, Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents: Non-Steroidal
Additional Keywords : Natural Substances Versus Drugs
[+]

Noni leaf extract protects against cerebral ischemia and osteoporosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:1039364. Epub 2018 Mar 25. PMID: 29765488
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Cerebral Ischemia, Osteoporosis
Pharmacological Actions : Neuroprotective Agents, Osteoprotective
[+]

Oleanolic acid and ursolic acid improve bone properties and calcium nalance and modulate vitamin D metabolism in aged female rats.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1435. Epub 2018 Dec 4. PMID: 30564129
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid, Ursolic Acid
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Oleanolic acid exerts bone protective effects in ovariectomized mice by inhibiting osteoclastogenesis.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2018 May ;137(1):76-85. Epub 2018 Apr 6. PMID: 29703642
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid
Diseases : Osteoporosis
Additional Keywords : Ovariectomy-Induced Changes
[+]

Oleuropein protects against bone loss associated with ovariectomy and inflammation. Oct 01, 2006

Pubmed Data : Clin Nutr. 2006 Oct;25(5):859-68. Epub 2006 Jun 5. PMID: 16740345
Article Published Date : Oct 01, 2006
Study Type : Animal Study
Additional Links
Substances : Oleuropein
Diseases : Inflammation, Osteoporosis
[+]

Olive oil can effectively reduce bone loss in ovariectomized rats.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 May ;11(5):1881-1888. Epub 2016 Mar 10. PMID: 27168821
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Olive oil prevents bone loss in tumor patients and has excellent prospects for curing osteoporosis after menopause.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Interv Aging. 2014 ;9:2087-95. Epub 2014 Dec 2. PMID: 25506212
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Cervical Cancer, Endometrial Cancer, Osteoporosis, Ovarian Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Malondialdehyde Down-regulation
[+]

Olives prevent bone loss caused by ovariectomy and chemically induced inflammation in rats.May 01, 2007

Pubmed Data : Br J Nutr. 2007 May;97(5):1012-20. PMID: 17408530
Article Published Date : May 01, 2007
Study Type : Animal Study
Additional Links
Substances : Olive
Diseases : Fibrinogen: Elevated, Osteoporosis, Osteoporosis: Age-Related
[+]

Onion consumption may reduce the risk for osteoporosis. Jun 01, 2008

Pubmed Data : Bone. 2008 Jun;42(6):1154-63. Epub 2008 Feb 29. PMID: 18387868
Article Published Date : Jun 01, 2008
Study Type : Animal Study
Additional Links
Substances : Onion
Diseases : Osteoporosis
[+]

Oral administration of kaempferol inhibits bone loss in rat model of ovariectomy-induced osteopenia.Sep 30, 2017

Pubmed Data : Pharmacol Rep. 2017 Oct ;69(5):1113-1119. Epub 2017 May 13. PMID: 29031689
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Oral administration of quercetin or its derivatives inhibit bone loss in animal model of osteoporosis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:6080597. Epub 2020 Oct 27. PMID: 33194005
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Osteoprotective
[+]

Orthosiphon stamineus ameliorated postmenopausal osteoporosis.Dec 31, 2017

Pubmed Data : Menopause. 2018 02 ;25(2):202-210. PMID: 28926512
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Inflammation, Osteoporosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
[+]

P. mirifica is recommended for osteoporotic patients.Mar 31, 2016

Pubmed Data : J Nat Med. 2016 Apr ;70(2):225-33. Epub 2016 Jan 27. PMID: 26815435
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pueraria mirifica
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Paeonol inhibits RANKL-induced osteoclastogenesis by inhibiting ERK, p38 and NF-kappaB pathway.Jun 23, 2008

Pubmed Data : Eur J Pharmacol. 2008 Jun 24 ;588(1):124-33. Epub 2008 Apr 16. PMID: 18495114
Article Published Date : Jun 23, 2008
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Osteoporosis
Pharmacological Actions : NF-kappaB Inhibitor, Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Phellinus linteus extract protected against osteoporosis by balancing the number of osteoblasts and osteoclasts.Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(1):39-47. PMID: 27279443
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Phellinus Linteus
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Phloretin was effective in preventing estrogen deficiency-induced osteoclastogenic resorption.Sep 14, 2014

Pubmed Data : Phytomedicine. 2014 Sep 15 ;21(10):1208-15. Epub 2014 Jun 2. PMID: 24932975
Article Published Date : Sep 14, 2014
Study Type : Animal Study
Additional Links
Substances : Phloretin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Plum prevents bone loss in a male osteoporosis model in rats. Dec 01, 2006

Pubmed Data : Bone. 2006 Dec;39(6):1331-42. Epub 2006 Aug 4. PMID: 16890505
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Plum
Diseases : Osteoporosis
[+]

Polygonatum sibiricum protects against ovariectomy-induced bone loss in rats.Apr 28, 2011

Pubmed Data : J Ethnopharmacol. 2011 Apr 28. Epub 2011 Apr 28. PMID: 21550389
Article Published Date : Apr 28, 2011
Study Type : Animal Study
Additional Links
Substances : Polygonatum Sibiricum
Diseases : Osteoporosis, Ovariectomy Associated Adverse Changes, Postmenopausal Disorders
Additional Keywords : Ovariectomy-Induced Changes
[+]

Pomegranate improves depressive symptoms and bone properties in a menopausal syndrome model due to its estrogen content (estradiol, estrone and estriol). May 01, 2004

Pubmed Data : J Ethnopharmacol. 2004 May;92(1):93-101. PMID: 15099854
Article Published Date : May 01, 2004
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Depression: Postmenopausal, Estrogen Deficiency, Menopausal Syndrome, Osteoporosis
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
[+]

Pomegranate may be supportive in the preservation of bone density and the treatment of vaginal epithelial atrophy.Mar 29, 2018

Pubmed Data : J Obstet Gynaecol Res. 2018 Mar 30. Epub 2018 Mar 30. PMID: 29603520
Article Published Date : Mar 29, 2018
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Osteoporosis, Vaginal Atrophy
Pharmacological Actions : Osteoprotective
[+]

Pomegranate seed oil extract has therapeutic effects on osteoporosis.Dec 31, 2016

Pubmed Data : J Nutr Health Aging. 2017 ;21(10):1299-1306. PMID: 29188893
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pomegranate Seed
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts, Plant Oils
[+]

Poncirin inhibits osteoclast differentiation and bone loss.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2020 Jul 1 ;28(4):337-343. PMID: 31500404
Article Published Date : Jun 30, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Positive skeletal effect of two ingredients of Psoralea corylifolia L. on estrogen deficiency-induced osteoporosis and the possible mechanisms of action.Dec 04, 2015

Pubmed Data : Mol Cell Endocrinol. 2015 Dec 5 ;417:103-13. Epub 2015 Sep 28. PMID: 26419930
Article Published Date : Dec 04, 2015
Study Type : Animal Study
Additional Links
Substances : Babchi
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes, Plant Extracts
[+]

Possible osteoprotective effects of myricetin in STZ induced diabetic osteoporosis in rats.Nov 18, 2019

Pubmed Data : Eur J Pharmacol. 2019 Nov 19:172805. Epub 2019 Nov 19. PMID: 31756333
Article Published Date : Nov 18, 2019
Study Type : Animal Study
Additional Links
Substances : Myricetin
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Prolonged use of bisphophonates may lead to excess mineralization, resulting in microcracks that interfere with bone quality/strength. Jan 01, 2007

Pubmed Data : Joint Bone Spine. 2007 Jan;74(1):39-47. Epub 2006 Nov 28. PMID: 17196423
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Alendronate (trade name Fosamax) , Bisphosphonates, Risedronate
[+]

Protective effects of melon extracts on bone strength, mineralization, and metabolism.Aug 13, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Aug 14 ;8(8). Epub 2019 Aug 14. PMID: 31416178
Article Published Date : Aug 13, 2019
Study Type : Animal Study
Additional Links
Substances : Honeydew (melon)
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

Psoralea corylifolia extract ameliorates experimental osteoporosis in ovariectomized rats.Dec 31, 2006

Pubmed Data : Am J Chin Med. 2007 ;35(4):669-80. PMID: 17708633
Article Published Date : Dec 31, 2006
Study Type : Animal Study
Additional Links
Substances : Babchi
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Pu-erh tea extract can ameliorate ovariectomy-induced osteoporosis in animals.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:324. Epub 2017 May 31. PMID: 28620304
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Black Tea
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Pueraria lobate inhibits RANKL-mediated osteoclastogenesis.Dec 31, 2016

Pubmed Data : Am J Chin Med. 2017 ;45(8):1725-1744. Epub 2017 Nov 9. PMID: 29121799
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Kudzu
Diseases : Osteoporosis, Periodontitis, Rheumatoid Arthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Pueraria mirifica alleviates cortical bone loss in naturally menopausal monkeys.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Endocrinol. 2016 Nov ;231(2):121-133. Epub 2016 Sep 6. PMID: 27601445
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Pueraria mirifica
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

Pueraria mirifica prevents bone loss in ovariectomized rats.Dec 01, 2009

Pubmed Data : Eur J Pediatr. 2009 Dec;168(12):1541-2. Epub 2009 Mar 11. PMID: 18313241
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Pueraria mirifica
Diseases : Osteoporosis
[+]

Puerarin alleviates streptozotocin-induced osteoporosisApr 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 May 1 ;115:108570. Epub 2019 May 1. PMID: 31054509
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Osteoprotective
[+]

Puerarin and zinc additively prevent mandibular bone loss through inhibiting osteoclastogenesis in ovariectomized rats.Jul 31, 2017

Pubmed Data : Histol Histopathol. 2017 Aug ;32(8):851-860. Epub 2016 Dec 14. PMID: 27966208
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Puerarin, Zinc
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

Puerarin may play a protective role in diabetic osteoporosis.May 31, 2012

Pubmed Data : Mol Med Rep. 2012 Jun ;5(6):1419-22. Epub 2012 Apr 2. PMID: 22470138
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Diabetic Complications, Osteoporosis
Pharmacological Actions : Anti-Apoptotic, Osteoprotective
[+]

Puerarin stimulates osteogenic differentiation and bone formation.Mar 08, 2018

Pubmed Data : Curr Mol Med. 2018 Mar 9 ;17(7):488-496. PMID: 29256352
Article Published Date : Mar 08, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Puerarin
Diseases : Osteoporosis
Pharmacological Actions : Osteogenic
[+]

Pycnogenol® has a protective effect on ovariectomy-induced bone loss in rats.Dec 31, 2011

Pubmed Data : Phytother Res. 2012 Jan ;26(1):153-5. Epub 2011 Jun 28. PMID: 21710590
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis, Ovariectomy Associated Adverse Changes
Pharmacological Actions : Antioxidants
Additional Keywords : Ovariectomy-Induced Changes, Phytotherapy, Plant Extracts
[+]

Rats fed with canned soft drinks had higher concentrations of Aluminum in blood, liver and bone than rats fed with glass bottled soft drinks. Jan 01, 1994

Pubmed Data : Biometals. 1994 Jan ;7(1):57-60. PMID: 8118174
Article Published Date : Jan 01, 1994
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Aluminium Cans, Sugary soda
[+]

Red Yeast Rice significantly increases bone formation in the rabbit experimental model.Mar 29, 2008

Pubmed Data : Chin Med. 2008 Mar 29;3:4. PMID: 18373874
Article Published Date : Mar 29, 2008
Study Type : Animal Study
Additional Links
Substances : Red Yeast Rice
Diseases : Osteoporosis
[+]

Resveratraol may have bone preserving effects. Feb 20, 2007

Pubmed Data : Neurology. 2007 Feb 20;68(8):563-8. PMID: 20458604
Article Published Date : Feb 20, 2007
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Osteoporosis
[+]

Rosiglitazone causes bone loss in mice by suppressing osteoblast (bone-building cells) differentiation and bone formation.Mar 01, 2005

Pubmed Data : Endocrinology. 2005 Mar;146(3):1226-35. Epub 2004 Dec 9. PMID: 15591153
Article Published Date : Mar 01, 2005
Study Type : Animal Study
Additional Links
Diseases : Aging, Osteopenia, Osteoporosis
Additional Keywords : Accelerated Aging
Problem Substances : Rosiglitazone (trade name Avandia)
[+]

Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone.Jun 01, 2007

Pubmed Data : Endocrinology. 2007 Jun;148(6):2669-80. Epub 2007 Mar 1. PMID: 17332064
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Aging, Osteopenia, Osteoporosis
Additional Keywords : Accelerated Aging
Problem Substances : Rosiglitazone (trade name Avandia)

Copyright: rob3000 / 123RF Stock Photo

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Written by Linda Woolven & Ted Snider
A disturbing study was published on the leading class of ulcer medication. The study found that proton pump inhibitors erode your mind while they heal your body
Bergamot Improves Schizophrenic Brain Function
Written by GreenMedInfo Research Group
Bergamot oranges are bitter fruits that grow in one of the world’s most beautiful coastal regions. Could the scenic ocean vistas be responsible for the calm, relaxing effects we derive from smelling and ingesting the bright, citrus essence of this amazing fruit?
This Humble Food Extract Puts Bone Drugs to Shame
Written by Sayer Ji, Founder
An ancient fermented food puts pharmaceutical drugs for bone loss to shame...
Open Letter to Nutritionists About the Fluoride Deception
Written by Karen Spencer
Fluoride is not a nutrient of any kind - essential, non-essential or micronutrient. Consumption does not provide any dental benefit, and there is no such thing as a fluoride deficiency
The Handmaid’s Tale Becomes a Reality
Written by Anne Marie Fine, ND
Environmental contaminants are causing decreased sperm production among men, with couples having difficulty conceiving and children being born with numerous health concerns
Milk Linked to Fractures: 10 Better Foods For Strong Bones
Written by Margie King, Health Coach
If milk doesn’t build strong bones, what does? Here are 10 foods proven to help reduce fractures and keep bones strong.

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