Polycystic Ovary Syndrome

Name	AC	CK
Inositol	4	40
Folic Acid	3	30
Buckwheat	2	20
D-Chiro-Inositol	2	20
Licorice	2	20
Vitamin D	1	20
Almond	1	10
Alpha-Lipoic Acid	1	10
Arginine	1	10
B-complex	1	10
Chinense Herbal Formula: Jinqi Jiangtang	1	10
Chinese Herbal Formula: Tiangui Fang	1	10
Cinnamon	1	10
Fenugreek	1	10
Myo-inositol	1	10
Omega-3 Fatty Acids	1	10
Selenium	1	10
Spearmint	1	10
Testosterone	1	10
Vinegar	1	10
Walnut	1	10
Ginseng (Korean)	2	4
Lactobacillus probiotics	1	2
Resveratrol	2	2
Thymoquinone	1	2
Tribulus	1	2
Berberine	1	1
Puerarin	1	1

Name	AC	CK	Focus
Insulin	1	10
Octylphenol	1	10

Name	AC	CK
Acupuncture	5	41
Dietary Modification: Low Starch/Low Dairy	1	10
Integrative Medicine	1	10
Moxibustion	1	10

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Berberine showed a promising prospect in treating polycystic ovary syndrome patients with insulin resistance.Dec 31, 2017

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Pubmed Data : Zhongguo Zhen Jiu. 2015 May ;35(5):461-4. PMID: 26255520

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Pubmed Data : J Obes Weight Loss Ther. 2015 Apr ;5(2). PMID: 26225266

Article Published Date : Mar 31, 2015

Study Type : Human Study

Additional Links

Diseases : Polycystic Ovary Syndrome

Therapeutic Actions : Dietary Modification: Low Starch/Low Dairy

Additional Keywords : Risk Reduction

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Bisphenol A may play a role in the aetiopathogenesis of polycystic ovary syndrome in adolescent girls.Mar 31, 2015

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Pubmed Data : Acta Paediatr. 2015 Apr ;104(4):e171-7. Epub 2015 Feb 3. PMID: 25469562

Article Published Date : Mar 31, 2015

Study Type : Human Study

Additional Links

Diseases : Bisphenol Toxicity, Polycystic Ovary Syndrome

Problem Substances : Bisphenol A

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Coenzyme Q10 and vitamin E had beneficial effects on cardiometabolic outcomes among women with polycystic ovary syndrome.Jan 31, 2019

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Pubmed Data : Arch Med Res. 2019 Feb ;50(2):1-10. Epub 2019 May 21. PMID: 31349945

Article Published Date : Jan 31, 2019

Study Type : Human Study

Additional Links

Substances : Coenzyme Q10, Vitamin E

Diseases : Polycystic Ovary Syndrome

Pharmacological Actions : Hypolipidemic

Additional Keywords : Natural Substance Synergy

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Consuming daily synbiotic pomegranate juice improved metabolic, oxidative, inflammatory, and blood pressure outcomes in females with PCOS.Nov 10, 2019

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Pubmed Data : J Endocrinol Invest. 2019 Nov 11. Epub 2019 Nov 11. PMID: 31713129

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Pubmed Data : Gynecol Endocrinol. 2017 Sep 26:1-6. Epub 2017 Sep 26. PMID: 28949260

Pubmed Data : Gynecol Endocrinol. 2010 Dec;26(12):861-8. Epub 2010 Jul 20. PMID: 20642382

Article Published Date : Dec 01, 2010

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Pubmed Data : Food Sci Nutr. 2019 Apr ;7(4):1426-1437. Epub 2019 Feb 27. PMID: 31024716

Article Published Date : Mar 31, 2019

Study Type : Human Study

Additional Links

Substances : Magnesium Sulfate

Diseases : Hyperandrogenemia, Insulin Resistance, Polycystic Ovary Syndrome

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Magnesium and zinc co-supplementation for 12 weeks among women with PCOS had beneficial effects on inflammation and oxidative stress. Nov 09, 2017

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Pubmed Data : Biol Trace Elem Res. 2017 Nov 10. Epub 2017 Nov 10. PMID: 29127547

Article Published Date : Nov 09, 2017

Study Type : Human Study

Additional Links

Substances : Magnesium, Zinc

Diseases : Polycystic Ovary Syndrome

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Gene Expression Regulation

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Magnesium-zinc-calcium-vitamin D supplementation in patients with PCOS had beneficial effects on insulin metabolism and markers of cardio-metabolic risk.Sep 30, 2017

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Pubmed Data : Arch Iran Med. 2017 Oct ;20(10):640-645. PMID: 29137465

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Pubmed Data : J Obstet Gynaecol India. 2019 Feb ;69(1):77-81. Epub 2018 May 28. PMID: 30814814

Article Published Date : Jan 31, 2019

Study Type : Human Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Polycystic Ovary Syndrome

Pharmacological Actions : Insulin Sensitizers

Additional Keywords : Superiority of Natural Substances versus Drugs

Problem Substances : Metformin

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NAC improves oocyte and embryo quality and could be administered as an alternative to metformin.Mar 31, 2016

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Pubmed Data : Reprod Fertil Dev. 2016 Apr ;28(6):723-31. PMID: 25482371

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Pubmed Data : J Res Med Sci. 2018 ;23:33. Epub 2018 Apr 26. PMID: 29887901

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Chamomile

Diseases : Polycystic Ovary Syndrome

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Organochlorine pesticides levels may play a role in the pathogenesis of polycystic ovary syndrome by affecting hormones levels.Feb 28, 2017

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Pubmed Data : Chemosphere. 2017 Mar ;171:595-600. Epub 2016 Dec 26. PMID: 28043072

Article Published Date : Feb 28, 2017

Study Type : Human Study

Additional Links

Diseases : Pesticide Toxicity , Polycystic Ovary Syndrome

Additional Keywords : Risk Factors

Problem Substances : Organochlorine pesticides, Pesticides

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Resveratrol significantly reduced ovarian and adrenal androgens.Oct 17, 2016

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Pubmed Data : J Clin Endocrinol Metab. 2016 Oct 18:jc20161858. Epub 2016 Aug 18. PMID: 27754722

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Pubmed Data : Rev Bras Ginecol Obstet. 2010 Nov ;32(11):541-8. PMID: 21271165

Article Published Date : Nov 01, 2010

Study Type : Human Study

Additional Links

Diseases : Adrenal Hyperandrogenism, Polycystic Ovary Syndrome

Additional Keywords : Diseases that are Linked

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There was a significant decrease in the serum anti-Mullerian hormone level after administration of cinnamon.Dec 31, 2016

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Pubmed Data : J Hum Reprod Sci. 2017 Jan-Mar;10(1):31-36. PMID: 28479753

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Pubmed Data : J Nutr Biochem. 2017 Apr 22 ;47:21-28. Epub 2017 Apr 22. PMID: 28501702

Article Published Date : Apr 21, 2017

Study Type : Animal Study

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Substances : Rutin

Diseases : Polycystic Ovary Syndrome

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Cinnamon improves metabolic factors without detectable effects on adiponectin in women with polycystic ovary syndrome.Dec 31, 2017

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Pubmed Data : Nat Med. 2019 Jul 22. Epub 2019 Jul 22. PMID: 31332392

Article Published Date : Jul 21, 2019

Study Type : Animal Study

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Diseases : Dysbiosis, Polycystic Ovary Syndrome

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Hydroalcoholic extract of flaxseed improves polycystic ovary syndrome in a rat model.May 31, 2018

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Pubmed Data : Iran J Basic Med Sci. 2018 Jun ;21(6):645-650. PMID: 29942457

Article Published Date : May 31, 2018

Study Type : Animal Study

Additional Links

Substances : Flaxseed

Diseases : Polycystic Ovary Syndrome, Testosterone: Too High

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Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.Mar 31, 2013

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Pubmed Data : Reprod Toxicol. 2013 Apr ;36:104-16. Epub 2013 Jan 25. PMID: 23453003

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Pubmed Data : J Ethnopharmacol. 2015 Jun 20 ;168:25-30. Epub 2015 Mar 27. PMID: 25818694

Article Published Date : Jun 19, 2015

Study Type : Animal Study

Additional Links

Substances : Thujae occidentalis

Diseases : Polycystic Ovary Syndrome

Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Additional Keywords : Phytotherapy

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Thymoquinone ameliorates some endocrine parameters and histological alteration in a rat model of polycystic ovary syndrome.Mar 31, 2018

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A mother's exposure to BPA during pregnancy may also lead to the development of PCOS in the female offspring.Mar 31, 2014

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Pubmed Data : Gynecol Endocrinol. 2014 Apr ;30(4):260-5. Epub 2014 Jan 7. PMID: 24397396

Article Published Date : Mar 31, 2014

Study Type : Review

Additional Links

Diseases : Polycystic Ovary Syndrome

Additional Keywords : Prenatal Epigenetic Programming, Risk Factors

Problem Substances : Bisphenol A

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Acupuncture may improve menstrual health and coping among women experiencing delays in becoming pregnant.Dec 31, 2013

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Pubmed Data : Reprod Biomed Online. 2016 Dec ;33(6):770-780. Epub 2016 Sep 16. PMID: 27717596

Article Published Date : Nov 30, 2016

Study Type : Review

Additional Links

Substances : Inositol

Diseases : Insulin Resistance, Obesity, Polycystic Ovary Syndrome

Pharmacological Actions : Insulin Sensitizers

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Insulin resistance directly exaggerates the androgenic potential within theca cells, suggesting the possible involvement of this ovarian metabolic phenotype in polycystic ovary syndrome hyperandrogenism.May 01, 2009

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Pubmed Data : Fertil Steril. 2009 May;91(5 Suppl):1990-7. Epub 2008 Jul 30. PMID: 18672234

Article Published Date : May 01, 2009

Study Type : In Vitro Study

Additional Links

Diseases : Insulin Resistance, Polycystic Ovary Syndrome

Additional Keywords : Diseases that are Linked

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N-3 fatty acids as preventive and therapeutic agents in attenuating PCOS complications.Dec 31, 2018

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View the Evidence: 130 Abstracts with Polycystic Ovary Syndrome Research

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Berberine showed a promising prospect in treating polycystic ovary syndrome patients with insulin resistance.Dec 31, 2017

BPA might be involved in the insulin-resistance and hyperandrogenism of polycystic ovary syndrome.Nov 29, 2017

N-acetyl-cysteine may be considered as an alternative supplement to metformin in PCOS patients.Nov 20, 2019

Serum 25-hydroxyvitamin D, follicle stimulating hormone and sex hormone-binding globulin were significantly lower in PCOS patients than controls.Aug 09, 2017

Serum level of vitamin D was associated with the risk of polycystic ovary syndrome.Sep 13, 2015

Vitamin D supplementation had beneficial on biomarkers of inflammation and oxidative stress among women with polycystic ovary syndrome.Feb 22, 2018

Vitamin D supplementation is sufficient for decreasing serum triglyceride.Dec 08, 2016

"Hyperandrogenism in women with polycystic ovary syndrome persists after menopause."Mar 01, 2011

A single bout of electroacupuncture remodels epigenetic and transcriptional changes in adipose tissue in polycystic ovary syndrome.Jan 29, 2018

Abdominal acupuncture treatment can improve the endocrine and metabolic function of patients with obesity-type polycystic ovarian syndrome. Aug 01, 2010

Acupuncture at Zhibian through Shuidao could significantly improve the basic temperature of patients with polycystic ovary syndrome, and regulate hormone level of reproductive endocrine.Apr 30, 2015

Acupuncture can effectively reduce FINS, HOMA-IR and WC levels in PCOS patients with abdominal obesity.Apr 24, 2018

Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin. Jun 01, 2005

Adrenal androgen excess in the polycystic ovary syndrome patients is related to an exaggerated secretory response of the adrenal cortex for DHEA and androstenedione (A4).Jul 01, 1998

An 8-week low-starch/low-dairy diet resulted in weight loss, improved insulin sensitivity and reduced testosterone in women with PCOS.Mar 31, 2015

Bisphenol A may play a role in the aetiopathogenesis of polycystic ovary syndrome in adolescent girls.Mar 31, 2015

Bodily retention of environmental organic pollutants-including PCBs, pesticides and PAHs-was associated with PCOS.Jul 31, 2015

BPA may play a major role in the pathogenesis of polycystic ovarian syndrome.Nov 30, 2017

Cinnamon reduces insulin resistance parameters in polycystic ovary syndrome.Apr 01, 2001

Cinnamon supplementation improved antioxidant status and serum lipid profile in women with PCOS.Dec 31, 2017

Co-administration of vitamin D and probiotic for 12 weeks to women with polycystic ovary syndrome had beneficial effects.Jan 20, 2019

Coenzyme Q10 and vitamin E had beneficial effects on cardiometabolic outcomes among women with polycystic ovary syndrome.Jan 31, 2019

Consuming daily synbiotic pomegranate juice improved metabolic, oxidative, inflammatory, and blood pressure outcomes in females with PCOS.Nov 10, 2019

Controlled-release alpha lipoic acid has a therapeutic effect in lean, nondiabetic patients with polycystic ovary syndrome.Mar 01, 2010

CoQ10 and vitamin E supplementation had beneficial effects on serum FBS and insulin levels as well as HOMA-IR and total testosterone levels.Sep 06, 2018

CoQ10 intake for 12 weeks in PCOS women significantly improved gene expression of LDLR, PPAR-γ, IL-1, IL-8 and TNF-α.Sep 25, 2017

CoQ10 supplementation had beneficial effects in subjects with PCOS, involving glucose metabolism, serum total and LDL-cholesterol levels.Dec 01, 2016

Curcumin seems to be an efficient reducer of oxidative stress related complications in patients with PCOS.Jan 07, 2020

D-chiro-inositol has a therapeutic effect in lean women with the polycystic ovary syndrome.Nov 01, 2002

Electroacupuncture improves oocytes' growth in patients with polycystic ovary syndrome.Nov 30, 2019

Endocrine disruptors such as BPA could modify neuroendocrine, reproductive, and metabolic regulation favouring PCOS development in adolescents.Jun 19, 2019

Flaxseed oil omega-3 supplementation for 12 weeks in women with PCOS had beneficial effects.Mar 31, 2018

Folate improves the effect of metformin treatment on vascular endothelial function in women with polycystic ovary sydrome. Feb 01, 2010

Folate supplementation for 8 weeks among women with PCOS had beneficial effects on metabolic profiles.Jun 30, 2014

Furocyst was efficacious in ameliorating the symptoms of polycystic ovary syndrome.Dec 31, 2014

Girls with PCOS and IR more hirsute, more AN, lower SHBG and higher fasting insulin levelsMay 31, 2010

in the form of a new beverage can improve insulin resistance, insulin, testosterone level, BMI, weight and waist circumference in PCOS. Dec 31, 2018

Increasing protein intake and restricting simple sugar intake may be therapeutic in polycystic ovary syndrome (PCOS)Mar 01, 2007

Inositol improves ovarian function in women with oligomenorrhea and polycystic ovaries.Nov 01, 2003

L-arginine appears to counteract the hypertensive properties of estradiol in patients with PCOS.Dec 01, 2010

Licorice reduces serum testosterone in healthy women. Oct 01, 2004

Licorice reduces the side effects of spironolactone in the treatment of polycystic ovary syndrome. Mar 01, 2007

Low intakes of dietary fiber and magnesium are associated with insulin resistance and hyperandrogenism in polycystic ovary syndrome.Mar 31, 2019

Magnesium and zinc co-supplementation for 12 weeks among women with PCOS had beneficial effects on inflammation and oxidative stress. Nov 09, 2017

Magnesium-zinc-calcium-vitamin D supplementation in patients with PCOS had beneficial effects on insulin metabolism and markers of cardio-metabolic risk.Sep 30, 2017

Myo-inositol decreases circulating insulin and serum testosterone as well as improvement in metabolic factors in women with polycystic ovary syndrome. Mar 01, 2009

Myo-inositol plus folic acid has a beneficial effect in improving ovarian function in women with oligomenorrhea and polycystic ovaries. Sep 01, 2007

Myo-inositol was useful in PCOS women in lowering BMI and ameliorating insulin sensitivity, and improving menstrual cycle.Dec 31, 2016

NAC can be used as a substitute for insulin-sensitizing agent in treatment of polycystic ovarian syndrome.Jan 31, 2019

NAC improves oocyte and embryo quality and could be administered as an alternative to metformin.Mar 31, 2016

Octylphenol may play a role in insulin resistance in PCOS patients.Oct 01, 2011

Omega-3 fatty acids supplementation for 12 weeks in PCOS women significantly improved gene expression of PPAR-γ and LDLR.Feb 23, 2017

Oral administration of chamomile capsule caused a significant decrease in total testosterone in patients with polycystic ovary syndrome.Dec 31, 2017

Organochlorine pesticides levels may play a role in the pathogenesis of polycystic ovary syndrome by affecting hormones levels.Feb 28, 2017

PCOS women are considered as a high-risk population for prediabetes.Sep 19, 2016

Progesterone resistance may play a role in polycystic ovary syndromeJun 01, 2011

Raw red onion consumption appears to be effective as a cholesterol-lowering food agent in women with polycystic ovary syndrome.Mar 31, 2014

Resveratrol may improve some outcomes of PCOS patients.Jul 20, 2019

Resveratrol significantly reduced ovarian and adrenal androgens.Oct 17, 2016

Selenium supplementation for 8 weeks among PCOS women had beneficial effects on reproductive outcomes, DHEA, hs-CRP, and MDA levels.Aug 11, 2015

Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. Jul 07, 2009

Taking myo-inositol by women with PCOS had beneficial effects on glycemic control, triglycerides and VLDL-cholesterol levels, and gene expression of PPAR-γ.Jan 03, 2019

The beneficial effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome.Jan 23, 2020

The Chinese herbal formula "tiangui fang" may have value in the treatment of hyperandrogenism and hyperinsulinism in polycystic ovary syndrome.Aug 01, 2000

The Chinese herbal formula Jinqi Jiangtang has beneficial effects in women with polycystic ovary syndrome (PCOS). Nov 01, 2006

The combined therapy of acupuncture, herbal medicine and clomiphene improves the pregnancy rate and reduces early abortion rate in patients. Jan 31, 2015

The compound found in buckwheat known as d-chiro-inositol have a therapeutic effect in polycystic ovary syndrome.Apr 29, 1999

The study concluded that there was a beneficial effect of vitamin D supplementation on ovulatory dysfunctions and blood pressure.Sep 30, 2017

There is a high prevalence of biochemical hyperandrogenism in patients with PCOS.Nov 01, 2010

There was a significant decrease in the serum anti-Mullerian hormone level after administration of cinnamon.Dec 31, 2016

These findings suggest the possibility of vinegar to restore ovulatory function through improving insulin sensitivity in PCOS patients.Dec 31, 2012

These observations confirm the potential role of BPA in polycystic ovary syndrome pathophysiology.Sep 09, 2016

Polycystic Ovary Syndrome

View the Evidence:
130 Abstracts with Polycystic Ovary Syndrome Research