Prostate Cancer

Name	AC	CK
Lycopene	15	111
Curcumin	63	98
Isoflavones	12	86
Genistein	19	75
Soy	11	75
Vitamin E	12	70
Coffee	3	62
Broccoli	10	60
Green Tea	14	58
Polyphenols	14	54
Vitamin C	5	53
Sulforaphane	23	52
Omega-3 Fatty Acids	5	50
Pomegranate	10	49
Selenium	8	46
Flaxseed	5	42
Tomato	8	41
Cruciferous Vegetables	5	35
Carotenoids	6	33
Fiber	3	32
Fish	3	30
EGCG (Epigallocatechin gallate)	15	26
Lignans	4	24
Rye	4	24
Vitamin B-12	3	24
Vitamin D	11	24
Resveratrol	18	23
Daidzein	3	22
Enterolactone	3	22
Nexrutine (Phellodendrom)	8	22
Mustard Greens	2	21
Vegetables: All	3	21
Black Tea	1	20
Bok Choy	1	20
Bran	2	20
Cabbage	1	20
Collards	1	20
Fruit: All	2	20
Gc protein-derived macrophage activating factor (GcMAF)	2	20
Kale	1	20
Soy Protein	6	20
beta-Carotene	2	20
Ellagic Acid	6	18
Apigenin	9	17
Flavonoids	13	16
Quercetin	10	16
Walnut	5	16
Indole-3-Carbinol	11	15
Milk Thistle	4	15
Saw Palmetto	6	15
Melatonin	4	14
Modified Citrus Pectin	4	14
phytoestrogens	4	14
Turmeric	4	13
Vitamin K2	3	13
Cranberry	3	12
Vitamin K	3	12
White Button Mushroom	2	12
Carrot	2	11
Onion	2	11
Antioxidant formulas	1	10
Cryptoxanthin	1	10
EPA (Eicosapentaenoic Acid)	1	10
Folic Acid	1	10
Garlic	1	10
Lutein	1	10
Magnesium	1	10
Silibinin	7	10
Silymarin	1	10
Vitamin K2: Menaquinones (MK-4-14)	1	10
Watermelon	1	10
Zeaxanthin	1	10
Catechin	7	9
Ginger	6	8
Gold (nanoparticles)	6	8
Phenethyl isothiocyanate	6	8
Sprouts	5	8
Vitamin E: Gamma-Tocopherol	3	8
Grape Seed Extract	6	7
Inositol Hexaphosphate	5	7
Sweet Potato	2	7
Cannabinoids	6	6
Fisetin	5	6
Ginsenosides	6	6
Homeopathic Medicine: All	3	6
Pterostilbene	5	6
Vitamin E: delta-tocopherol	4	6
Zinc	4	6
Alpha-Lipoic Acid	1	5
Arctigenin	4	5
Mulberry	1	5
Rice Bran	2	5
Thymoquinone	4	5
Zyflamend	4	5
Astaxanthin	3	4
Beans: All	3	4
Bee Propolis	3	4
Cannabidiol	4	4
Cannabinoids: Synthetic	4	4
Fermented Foods and Beverages	1	4
Fucoidan	3	4
Graviola	3	4
Isoliquiritigenin	3	4
Licorice	3	4
Luteolin	3	4
Reishi Mushroom	4	4
Rice: Brown	1	4
Tanshinone IIA	3	4
Ursolic Acid	3	4
Amygdalin	2	3
Anthocyanins	3	3
Antineoplaston A3	1	3
Argan Oil	2	3
Benzyl isothiocyanate	2	3
Black Cohosh	3	3
Maitake Mushroom	2	3
Nettle	3	3
Oleuropein	2	3
Papaya	3	3
Peanut	2	3
Phellinus Linteus	2	3
Piceatannol	3	3
Pygeum Bark	3	3
Red Yeast Rice	2	3
Shallot	2	3
Urolithin A	2	3
Xanthohumol	2	3
6-Shogaol	2	2
Anandamide	2	2
Artemisinin	2	2
Ashwagandha	2	2
Baicalein	2	2
Beet	2	2
Berberine	2	2
Betulinic acid	2	2
Blueberry	2	2
Broccoli Sprouts	1	2
CLA (Conjugated Linoleic Acid)	1	2
Caffeic acid phenethyl ester	1	2
Cannabis	2	2
Carnosic Acid	2	2
Carnosol	2	2
Cocoa	1	2
Coumestrol	2	2
Cucumber	1	2
Cucurbitacin B	1	2
DHA (Docosahexaenoic Acid)	2	2
Deguelin	2	2
Delphinidin	2	2
Diosgenin	2	2
Endocannabinoids	2	2
Enterodiol	2	2
Eucalyptus	1	2
False Black Pepper	2	2
Ferulic acid	2	2
Fucoxanthin	2	2
Gallic Acid	1	2
Gamma-Linoleic Acid (GLA)	1	2
Garcinia dulcis	1	2
Geraniol	2	2
Ginkgo biloba	2	2
Goldenrod	1	2
Guggul	2	2
Hibiscus sabdariffa	1	2
Holy Basil	2	2
Homeopathic Medicine: Sabal serrulata	1	2
Honokiol	2	2
Hops	2	2
Lichens	2	2
Litchi	1	2
Lupeol	1	2
Magnolia grandifloris (honokiol)	1	2
Mangiferin	2	2
Mango	1	2
Menthol	2	2
Myricetin	1	2
NAC (N-acetyl-L-cysteine)	1	2
Naringenin	2	2
Neem	2	2
Nordihydroguaiaretic acid (NDGA)	1	2
Oleanolic acid	1	2
Panax Ginseng	1	2
Parthenolide	1	2
Peppermint	2	2
Phyllanthus amarus	2	2
Phyllanthus niruri (Stonebreaker)	2	2
Phyllanthus urinaria	2	2
Piperlongumine	2	2
Plant Sterols/Stanols	1	2
Potato	2	2
Procyanidin B2	2	2
Rose	2	2
Sea Cucumber	1	2
Strawberry	2	2
Tannic Acid	2	2
Tocopherols	1	2
Tocotrienol: Delta	2	2
Tocotrienols	1	2
White Tea	1	2
acetyl-11-keto-beta-boswellic acid	1	2
AHCC	1	1
Agaricus Blazei	1	1
Andrographis	1	1
Angelica	1	1
Astragaloside	1	1
Avocado	1	1
Bael	1	1
Bee Pollen	1	1
Berbamine	1	1
Berries: All	1	1
Beta-Elemene	1	1
Black Raspberry	1	1
Black Tea Theaflavins	1	1
Blackberry	1	1
Bloodroot	1	1
Burdock	1	1
Caffeic Acid	1	1
Capsaicin	1	1
Celery	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chickpea	1	1
Chinese Skullcap	1	1
Chrysanthemum Indicum	1	1
Chrysin	1	1
Cinnamaldehyde	1	1
Cinnamon	1	1
Citrus Peel	1	1
Citrus naringin	1	1
Coriandrum sativum	1	1
Corn Silk	1	1
Corn: Purple	1	1
Cucurbitacin D	1	1
Cucurbitacin E	1	1
DIM (3,3'-diindolylmethane)	1	1
Damnacanthal	1	1
Dandelion	1	1
Decursin	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Demethoxycurcumin	1	1
Dibenzoylmethane (DBM)	1	1
Diosmin	1	1
Equol	1	1
Essiac Tea	1	1
Eugenol	1	1
Evening Primrose Oil	1	1
Fig	1	1
Fulvic Acid	1	1
Garcinia xanthochymus	1	1
Gingerol	1	1
Goji	1	1
Grape	1	1
Green Leafy Vegetables	1	1
Honey	1	1
Huaier (Trametes robiniophila murr)	1	1
Hydroxytyrosol	1	1
Kava Kava	1	1
Legumes	1	1
Lemongrass	1	1
Ligustrazine	1	1
MSM (Methylsulfonylmethane)	1	1
Marijuana	1	1
Mistletoe	1	1
Mung Bean	1	1
Mushrooms: All	1	1
Myrrh	1	1
Neoxanthin	1	1
OPC (Oligomeric Proanthocyanidins)	1	1
Olive leaf extract	1	1
Orange	1	1
Oyster Mushroom	1	1
Passion Flower	1	1
Persimmon	1	1
Phloretin	1	1
Pine Bark Extract	1	1
Piper cubeba (Cubeb)	1	1
Piperine	1	1
Pomegranate Peel	1	1
Prickly Pear Cactus	1	1
Progesterone	1	1
Propolis: Brazillian	1	1
Prunella vulgaris	1	1
Pumpkin	1	1
Pumpkin Seeds	1	1
Punicalagin	1	1
Punicic acid	1	1
Radish	1	1
Raspberry	1	1
Red Clover	1	1
Red Sage	1	1
Rosemaric Acid	1	1
Rosemary	1	1
Ruta Graveolens	1	1
Sandalwood	1	1
Seaweed: Brown	1	1
Secoisolariciresinol diglucoside (SDG)	1	1
Sesame Seeds	1	1
Sessile Joyweed	1	1
Silver (nanoparticles)	1	1
Stilbenes	1	1
Syrian rue	1	1
Tabebuia	1	1
Tangeretin	1	1
Tea	1	1
Testosterone	1	1
Thymol	1	1
Tocotrienol: Gamma	1	1
Venom: Snake	1	1
Vitamin E: Gamma-tocotrienol	1	1
Wedelia chinensis	1	1
Xanthones	1	1
Zerumbone	1	1
Chaste Tree (Chasteberry)	1	0
Vitex Agnus	1	0

Name	AC	CK
Pesticides	9	73
Organochlorine pesticides	3	30
Bisphenol A	12	26
Virus: Xenotropic murine leukemia virus-related virus (XMRV)	5	22
Alcohol Consumption	1	20
Dieldrin	2	20
Mass Market Vitamins	2	20
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	20
Statin Drugs	2	20
2,4-Dichlorophenoxyacetic acid	2	11
Bisphosphonates	2	11
5-Alpha Reductase Inhibitors	1	10
Chlordecone	1	10
Chlorinated Polycyclic Ketone	1	10
Hexachlorocyclohexane	1	10
Hydrogenated Oil	1	10
Leuprorelin (Lupron)	1	10
Organochlorine compounds	1	10
Persistent organic pollutants (POPs)	1	10
Prednisone	1	10
Sugar Sweetened Beverages	1	10
Terbufos	1	10
Warfarin	1	10
Zoledronic Acid	1	10
Phthalates	1	5
Cow Milk	2	2
Meat: Cooked	1	2
Aluminum	1	1
Antiperspirants	1	1
Ecotropic murine leukemia viruses (E-MLV)	1	1
Endocrine Disrupting Chemicals (EDCs)	1	1
Hydrocarbons	1	1
Mineral Oil	1	1
N-Nitrosamines	1	1
Paraffin	1	1
Polycyclic aromatic hydrocarbon	1	1
Simian virus 40 (SV40)	1	1
Xenotropic murine leukemia virus (X-MLV)	1	1

Name	AC	CK
Dietary Modification: Mediterranean Diet	4	40
Sunlight exposure	3	21
Dietary Modification: Low Fat Diet	1	10
Dietary Modification: Vegan Diet	1	10
Dietary Modification: Vegetarian	1	10
Exercise: Strenuous	1	10
Qigong	1	10
Tai Chi	1	10
Ultrasound therapy	1	10
Homeopathic Treatment	2	4
Hyperbaric Treatment	1	3
Dietary Modification: Low Carbohydrate/Ketogenic	1	2
Exercise	2	2
Exercise: Aerobic	1	2
Light Therapy	1	2
Dietary Modification: Paleolithic/Stone Age Diet	1	1

Name	AC	CK
Shift Work	2	30
Western Diet	2	24
Radiotherapy	3	18
Brachytherapy	1	10
Vaccination: All	1	2
Castration	1	1
Vasectomy	1	1

[+]

Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

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Pubmed Data : Sci Rep. 2016 Sep 26 ;6:33711. Epub 2016 Sep 26. PMID: 27665923

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Pubmed Data : Carcinogenesis. 2017 Nov 8. Epub 2017 Nov 8. PMID: 29126152

Article Published Date : Nov 07, 2017

Study Type : Meta Analysis, Review

Additional Links

Diseases : Prostate Cancer

Additional Keywords : Risk Factors

Anti Therapeutic Actions : Shift Work

[+]

The present meta-analysis showed that intake of vitamin C from food was inversely associated with prostate cancer risk. Dec 31, 2014

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Pubmed Data : J Cancer. 2015 ;6(9):913-21. Epub 2015 Jul 28. PMID: 26284143

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Pubmed Data : Phytother Res. 2015 Jan ;29(1):40-2. Epub 2014 Sep 9. PMID: 25205619

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Nexrutine (Phellodendrom)

Diseases : Prostate Cancer

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Plant Extracts

[+]

The clinical cases presented here reinforce the hypothesis that GcMAF could become part of anticancer immunotherapeutic regimens.Jul 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncoimmunology. 2013 Aug 1 ;2(8):e25769. Epub 2013 Jul 29. PMID: 24179708

Article Published Date : Jul 31, 2013

Study Type : Human Study

Additional Links

Substances : Gc protein-derived macrophage activating factor (GcMAF)

Diseases : Bladder Cancer, Breast Cancer, Follicular Lymphoma, Laryngeal Cancer, Lymphoma, Ovarian Cancer, Prostate Cancer, Tongue Cancer

Pharmacological Actions : Immunomodulatory

Additional Keywords : Nagalase, Significant Treatment Outcome

[+]

A combination of soy, isoflavones, lycopene, silymarin and antoxidants significantly increases PSA doubling time in men with prostate cancer. Dec 01, 2005

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Pubmed Data : Eur Urol. 2005 Dec;48(6):922-30; discussion 930-1. Epub 2005 Oct 17. PMID: 16263208

Article Published Date : Dec 01, 2005

Study Type : Human Study

Additional Links

Substances : Antioxidant formulas, Isoflavones, Lycopene, Milk Thistle, Soy

Diseases : Prostate: PSA Doubling, Prostate Cancer

[+]

A diet rich in healthy plant foods and especially total or raw vegetable may protect against prostate cancer.Jan 26, 2017

[+]

Allium vegetables are related to decreased risk of prostate cancer. Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asian Pac J Cancer Prev. 2013 ;14(7):4131-4. PMID: 23991965

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Substances : Garlic, Onion

Diseases : Prostate Cancer

Pharmacological Actions : Chemopreventive

[+]

Benign tissue inflammation was positively associated with prostate cancer.Jul 27, 2017

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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2017 Jul 28. Epub 2017 Jul 28. PMID: 28754796

Article Published Date : Jul 27, 2017

Study Type : Human Study

Additional Links

Diseases : Inflammation, Prostate Cancer

Additional Keywords : Increased Risk

[+]

Click here to read the entire abstract

Pubmed Data : J Natl Cancer Inst. 2009 Mar 18;101(6):432-5. Epub 2009 Mar 10. PMID: 19276452

Article Published Date : Mar 18, 2009

Study Type : Human Study

Additional Links

Substances : Folic Acid

Diseases : Prostate Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Whole Food Nutrients are Superior to their Synthetic Equivalents

[+]

Dietary intakes of alpha and delta tocopherol were inversely associated with prostate cancer aggressiveness.Aug 31, 2015

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Pubmed Data : Int J Cancer. 2019 Sep 4. Epub 2019 Sep 4. PMID: 31486077

[+]

Low blood Mg levels and a high Ca/Mg ratio were significantly associated with high-grade prostate cancer.Jan 01, 2011

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Pubmed Data : PLoS One. 2011 ;6(4):e18237. Epub 2011 Apr 25. PMID: 21541018

Article Published Date : Jan 01, 2011

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Prostate Cancer

[+]

Low vitamin D status is associated with inflammation in patients with prostate cancer.Mar 27, 2017

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Pubmed Data : Oncotarget. 2017 Mar 28 ;8(13):22076-22085. PMID: 28423553

Article Published Date : Mar 27, 2017

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : C-Reactive Protein, Inflammation, Prostate Cancer, Vitamin D Deficiency

Additional Keywords : Risk Factors

[+]

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2010 Oct;62(7):996-1000. PMID: 20924975

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Isoflavones, Soy

Diseases : Prostate Cancer, Radiation Induced Illness

Anti Therapeutic Actions : Radiotherapy

[+]

Click here to read the entire abstract

Pubmed Data : Int J Cancer. 2005 Nov 20;117(4):667-9. PMID: 15945102

Pubmed Data : Prostate. 2010 Aug 26. Epub 2010 Aug 26. PMID: 20799287

Article Published Date : Aug 26, 2010

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Pubmed Data : Int J Environ Res Public Health. 2011 Sep ;8(9):3579-90. Epub 2011 Sep 2. PMID: 22016704

Article Published Date : Sep 01, 2011

Study Type : Human Study

Additional Links

Diseases : Mesothelioma, Prostate Cancer, Respiratory Cancers

Problem Substances : 2,4-Dichlorophenoxyacetic acid

[+]

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Pubmed Data : Am J Clin Nutr. 2016 Jan 27. Epub 2016 Jan 27. PMID: 26817504

Article Published Date : Jan 26, 2016

Study Type : Human Study

Additional Links

Substances : Lycopene

Diseases : Prostate Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Risk Reduction

[+]

[+]

Vitamin E supplementation is associated with a statistically significant reduction in the incidence of prostate cancer. Nov 01, 2007

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Pubmed Data : Ann Saudi Med. 2007 Nov-Dec;27(6):409-14. PMID: 18059122

Article Published Date : Nov 01, 2007

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Pubmed Data : J Nutr. 2010 Dec;140(12):2180-6. Epub 2010 Oct 27. PMID: 20980650

Article Published Date : Dec 01, 2010

Study Type : Human Study

Additional Links

Substances : Bran , Fiber, Rye

Diseases : Hyperinsulinism, Prostate Cancer

[+]

Zolendronic acid results in renal impairment in 23,8% of the prostate cancer patients it is administered to.Mar 15, 2007

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Pubmed Data : Cancer. 2007 Mar 15;109(6):1090-6. PMID: 17311345

Article Published Date : Mar 15, 2007

Study Type : Human Study

Additional Links

Diseases : Kidney Damage: Drug-Induced, Prostate Cancer

Problem Substances : Bisphosphonates, Zoledronic Acid

Adverse Pharmacological Actions : Nephrotoxic

[+]

Apigenin could be a useful compound to prevent proliferation and migration of cancer cells as well as cancer stem cells.Aug 24, 2016

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Pubmed Data : Life Sci. 2016 Aug 25. Epub 2016 Aug 25. PMID: 27569589

Article Published Date : Aug 24, 2016

Study Type : Human In Vitro

Additional Links

Substances : Apigenin

Diseases : Prostate Cancer, Prostate Cancer Stem Cells

Pharmacological Actions : Anti-metastatic, Antiproliferative , NF-kappaB Inhibitor

Additional Keywords : Dose Response

[+]

Gamma- tocopherol was superior to alpha- tocopherol in the inactivation of the Kinase Akt.Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Med Case Reports. 2009;3:9295. Epub 2009 Nov 24. PMID: 20062784

Article Published Date : Jan 01, 2009

Study Type : Human: Case Report

Additional Links

Substances : Vitamin B-12

Diseases : Anemia: Pernicious, Prostate Cancer, Vitamin B 12 Deficiency

Additional Keywords : Diseases that are Linked

[+]

"Dietary Resveratrol Prevents Development of High-Grade Prostatic Intraepithelial Neoplastic Lesions."Dec 16, 2012

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Pubmed Data : Cancer Prev Res (Phila). 2012 Dec 17. Epub 2012 Dec 17. PMID: 23248098

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Pubmed Data : Br J Nutr. 2012 Jan 16:1-9. Epub 2012 Jan 16. PMID: 22244053

Aerobic training and green tea extract protect against N-Methyl-N-nitrosourea-induced prostate cancer.May 28, 2019

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Pubmed Data : Med Sci Sports Exerc. 2019 May 29. Epub 2019 May 29. PMID: 31157709

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Pubmed Data : Indian J Biochem Biophys. 2012 Dec ;49(6):451-7. PMID: 23350280

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Pubmed Data : Int J Mol Sci. 2016 02 22 ;17(2):264. Epub 2016 Feb 22. PMID: 26907265

Article Published Date : Jan 21, 2016

Study Type : Animal Study

Additional Links

Substances : Benzyl isothiocyanate

Diseases : Prostate Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Cell cycle arrest, Chemopreventive

Additional Keywords : Isothiocyanates

[+]

Bioactive soybean components inhibit the growth and metastasis of androgen-sensitive human prostate tumors in miceOct 01, 2002

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Pubmed Data : Prostate. 2002 Oct 1;53(2):143-53. PMID: 12242729

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Pubmed Data : Pharm Res. 2009 Oct;26(10):2324-31. Epub 2009 Aug 8. PMID: 19669099

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Pubmed Data : Int J Cancer. 2009 Jul 1;125(1):1-8. PMID: 19326431

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin, Resveratrol

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Natural Substance Synergy, Stilbenes

[+]

Combining green tea polyphenols and quercetin significantly enhanced the antiproliferative and proapoptotic effect in vivo. Dec 31, 2013

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Pubmed Data : J Nutr Biochem. 2014 Jan ;25(1):73-80. Epub 2013 Oct 10. PMID: 24314868

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Green Tea, Quercetin

Diseases : Prostate Cancer, Prostate Cancer: Prevention

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemopreventive

Additional Keywords : Bioavailability, Multidrug Resistance, Natural Substance Synergy

[+]

Compounds contained with Phellodendron amurense inhibits proliferation of cancer cells in the transgenic mouse model of prostate cancer.Dec 23, 2008

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Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:2951428. Epub 2019 Jul 17. PMID: 31391857

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Dandelion , Lemongrass

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy, Selective Cytotoxicity

[+]

Daytime blue light enhances the nighttime circadian melatonin inhibition of human prostate cancer growth.Dec 31, 2014

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Pubmed Data : Comp Med. 2015 ;65(6):473-85. PMID: 26678364

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Pubmed Data : Endocrinology. 2014 Mar ;155(3):805-17. Epub 2014 Jan 1. PMID: 24424067

Article Published Date : Feb 28, 2014

Study Type : Animal Study

Additional Links

Diseases : Prostate Cancer

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

[+]

Dietary fat enhances prostate cancer progression.Aug 31, 2014

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Pubmed Data : J Agric Food Chem. 2019 Jan 9 ;67(1):229-235. Epub 2018 Dec 28. PMID: 30562012

Article Published Date : Jan 08, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Grape Seed Extract, Proanthocyanidins

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

[+]

Loading chemotherapeutic drugs into multifunctional gold nanospheres can increase antitumor potency.Dec 31, 2014

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Pubmed Data : J Drug Target. 2015 ;23(6):568-76. Epub 2015 Mar 4. PMID: 25738990

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Pubmed Data : Cancer Res. 2009 Jan 15 ;69(2):518-25. PMID: 19147565

Article Published Date : Jan 14, 2009

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Garcinia dulcis

Diseases : Prostate Cancer

Pharmacological Actions : Anti-Angiogenic, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Dose Response

[+]

Myricetin effectively represses the malignant progression of prostate cancer.Jul 24, 2018

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Pubmed Data : Br J Cancer. 2006 Aug 7;95(3):282-8. Epub 2006 Jul 25. PMID: 16868541

Pubmed Data : Mol Carcinog. 2006 Jun;45(6):436-42. PMID: 16637061

Article Published Date : Jun 01, 2006

Study Type : Animal Study

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Substances : Milk Thistle

Diseases : Prostate Cancer

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Soy and rye diets have an inhibitory effect on the development of prostate cancer in rats.Jan 01, 2008

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Pubmed Data : Med Princ Pract. 2008;17(2):131-5. Epub 2008 Feb 19. PMID: 9687986

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Pubmed Data : J Nutr. 1999 Sep;129(9):1628-35. PMID: 10460196

Article Published Date : Sep 01, 1999

Study Type : Animal Study

Additional Links

Substances : Daidzein, Genistein, Soy Protein

Diseases : Prostate Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Antineoplastic Agents, Apoptotic, Cell cycle arrest

[+]

Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis.Nov 01, 2008

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Pubmed Data : Clin Cancer Res. 2008 Nov 1;14(21):6855-66. PMID: 18980980

The homeopathic remedy Sabal serrulata appears to inhibit the growth of human prostate cancer growth in cellular and animal models. Dec 01, 2006

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Pubmed Data : Integr Cancer Ther. 2006 Dec;5(4):362-72. PMID: 17101766

Article Published Date : Dec 01, 2006

Study Type : Animal Study

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Substances : Homeopathic Medicine: Sabal serrulata

Diseases : Prostate Cancer

Therapeutic Actions : Homeopathic Treatment

Pharmacological Actions : Antiproliferative

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The phytochemical synergy among the constituents of Graviola leaf extracts protected against prostate cancer, and enhanced the bioavailability of rutin 7-fold and quercetin 3-fold.Apr 10, 2015

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Pubmed Data : Carcinogenesis. 2015 Apr 11. Epub 2015 Apr 11. PMID: 25863125

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Pubmed Data : Nutr Cancer. 2015 ;67(2):305-15. Epub 2015 Feb 9. PMID: 25664890

Article Published Date : Dec 31, 2014

Study Type : Animal Study

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Substances : Tomato

Diseases : Inflammation, Prostate Cancer

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Gene Expression Regulation, Tumor Microenvironment

[+]

The use of animal cells in the production of vaccines may cause infection by endogenous retroviruses associated with chronic fatigue and prostate cancer.May 01, 2010

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Pubmed Data : Biologicals. 2010 May;38(3):371-6. Epub 2010 Apr 8. PMID: 20378372

Article Published Date : May 01, 2010

Study Type : Animal Study

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Diseases : Chronic Fatigue Syndrome, Prostate Cancer, Retroviruses, Vaccine-induced Toxicity

Anti Therapeutic Actions : Vaccination: All

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These findings implicate dietary stilbenes as an attractive miRNA-mediated chemopreventive and therapeutic strategy.Aug 05, 2015

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Pubmed Data : Oncotarget. 2015 Aug 6. Epub 2015 Aug 6. PMID: 26318586

Article Published Date : Aug 05, 2015

Study Type : Animal Study

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Substances : Pterostilbene, Resveratrol

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Chemopreventive, MicroRNA modulator

Additional Keywords : Epigenetic Modification In Cancer

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These results demonstrate the promising synergistic effect of resveratrol and peanut stem extract combined with radiation in the treatment of radioresistant PCa.Dec 31, 2016

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Pubmed Data : PLoS One. 2017 ;12(1):e0169204. Epub 2017 Jan 12. PMID: 28081154

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Pubmed Data : Carcinogenesis. 2011 Dec ;32(12):1872-80. Epub 2011 Sep 26. PMID: 21948980

Article Published Date : Nov 30, 2011

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Polyphenols, Sweet Potato

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

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This study supports the hypothesis that a diet rich in tomato and broccoli can reduce or prevent dietary carcinogen induced cancers.Dec 31, 2012

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Pubmed Data : PLoS One. 2013 ;8(11):e79842. Epub 2013 Nov 27. PMID: 24312188

Article Published Date : Dec 31, 2012

Study Type : Animal Study

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Substances : Broccoli, Tomato

Diseases : Breast Cancer, Cancers: All, Colorectal Cancer: Prevention , Prostate Cancer: Prevention

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

Additional Keywords : Dietary Concentrations, Dietary Modification

Problem Substances : Meat: Cooked

[+]

Thymoquinone may prove to be effective in treating hormone-sensitive as well as hormone-refractory prostate cancer.Aug 14, 2007

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Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:287358. Epub 2013 Aug 24. PMID: 24062781

Article Published Date : Dec 31, 2012

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Vitamin K2

Diseases : Prostate Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor

Additional Keywords : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Apoptotic, NF-kappaB Inhibitor, prostate cancer, Vitamin K2

[+]

Walnuts reduced prostate tumor growth by affecting energy metabolism along with decreased plasma IGF-1 and cholesterol.Nov 30, 2014

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Pubmed Data : J Med Food. 2014 Dec ;17(12):1281-6. PMID: 25354213

3,3'-diindolylmethane (DIM) has multiple anticancer properties making it one of the most hopeful phytochemicals in treating and preventing prostate cancer and HGPIN.Aug 31, 2014

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Pubmed Data : J Biomed Res. 2014 Sep ;28(5):339-48. Epub 2014 Apr 20. PMID: 25332705

Article Published Date : Aug 31, 2014

Study Type : Review

Additional Links

Substances : Cruciferous Vegetables, Indole-3-Carbinol

Diseases : High-Grade Prostatic Intraepithelial Neoplastic Lesions, Prostate Cancer, Prostate Cancer: Prevention

Pharmacological Actions : Angiogenesis Inhibitors, Anti-Estrogenic, Anti-Inflammatory Agents, Anticarcinogenic Agents, Antiproliferative , Apoptotic, Chemopreventive

Additional Keywords : Risk Reduction

[+]

3,3'-Diindolylmethane inhibits histone deacetylase activity in prostate cancer cells.Sep 14, 2012

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2013 ;2013:575482. Epub 2013 Apr 4. PMID: 23691264

Article Published Date : Dec 31, 2012

Study Type : Review

Additional Links

Substances : Blueberry, Pterostilbene

Diseases : Breast Cancer, Cardiovascular Disease, Colon Cancer, Diabesity , Esophageal Cancer, Gastric Cancer, Prostate Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Cardioprotective, Neuroprotective Agents

Additional Keywords : Natural Substance/Drug Synergy

[+]

[+]

An anthocyanin rich black carrot extract was a potent anticancer agent in vitro. Aug 31, 2013

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Pubmed Data : Plant Foods Hum Nutr. 2013 Sep ;68(3):293-8. PMID: 23828497

Article Published Date : Aug 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Carrot

Diseases : Breast Cancer, Breast Cancer: Triple Negative , Cancers: All, Colon Cancer, Neuroblastoma, Prostate Cancer

Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Antiproliferative , Cytotoxic

Additional Keywords : Plant Extracts, Selective Cytotoxicity

Problem Substances : 2,4-Dichlorophenoxyacetic acid

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View the Evidence: 732 Abstracts with Prostate Cancer Research

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Coffee intake was associated with reduced risk of oral, pharynx, liver, colon, prostate, endometrial cancer and melanoma, but increased lung cancer risk.Sep 25, 2016

Cruciferous vegetables intake is related to the decreased risk of prostate cancer.Jan 31, 2012

Evidence exists indicating that Brassica vegetables reduce prostate cancer risk.Jan 01, 2002

In this meta-analysis a positive relation between all-NSAID intake and prostate cancer was observed.Dec 31, 2013

Increased dietary and circulating lycopene are associated with reduced prostate cancer risk.Apr 24, 2017

Intake of concentrated green tea catechin preparations may confer a significant protective effect to carriers of early neoplastic lesions in the prostate.Oct 01, 2019

Integrated evidence from this meta-analysis suggests that shift work is significantly associated with an increased risk of prostate cancer.Nov 07, 2017

The present meta-analysis showed that intake of vitamin C from food was inversely associated with prostate cancer risk. Dec 31, 2014

These findings suggest that coffee consumption may be associated with a reduced risk of prostate cancer.Dec 31, 2014

This dose-response meta-analysis demonstrated that higher lycopene consumption was linearly associated with a reduced risk of PC.Jul 31, 2015

This meta-analysis provides strongest evidence supporting that Type 2 diabetes is significantly inversely associated with risk of developing prostate cancer.May 31, 2013

By the end of the neoadjuvant treatment, 81% of the patients had a decline in prostate-specific antigen.Dec 31, 2014

The clinical cases presented here reinforce the hypothesis that GcMAF could become part of anticancer immunotherapeutic regimens.Jul 31, 2013

A combination of soy, isoflavones, lycopene, silymarin and antoxidants significantly increases PSA doubling time in men with prostate cancer. Dec 01, 2005

A diet rich in healthy plant foods and especially total or raw vegetable may protect against prostate cancer.Jan 26, 2017

A dietary change towards a mediterranean-style pattern is both achievable and could be beneficial for men with prostate cancer.Dec 31, 2014

A high intake of fish may decrease the risk of prostate cancer death. May 01, 2009

A human clinical study demonstrates that diets rich in cruciferous vegetables may reduce the risk of prostate cancer.Jan 01, 2008

A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro.Aug 01, 2003

A Mediterranean-style diet or DASH diet could help reduce the odds of high aggressive prostate cancer.Sep 04, 2018

A pilot trial of pembrolizumab plus prostatic cryotherapy for men with newly diagnosed oligometastatic hormone-sensitive prostate cancer.Oct 13, 2019

A polyphenol-rich whole food supplement significantly effected the rate of PSA progression among men with prostate cancer.Mar 10, 2014

A western-style diet may lead to increased risks for prostate cancer, especially aggressive prostate cancer.May 01, 2008

After 14 to 25 weekly administrations of GcMAF all patients had very low serum Nagalase levels equivalent to those of healthy control, indicating that these patients are tumor-free.Jun 30, 2008

Allium vegetables are related to decreased risk of prostate cancer. Dec 31, 2012

Benign tissue inflammation was positively associated with prostate cancer.Jul 27, 2017

Chlordecone exposure increases the risk of prostate cancer.Jul 20, 2010

Consumption of sugars from sugar-sweetened beverages was associated with increased risk of prostate cancer.Jul 25, 2018

Cruciferous vegetable consumption was strongly associated with reduced risk of prostate cancer progression.Jun 30, 2012

Curcumin improved total antioxidant capacity and lowered PSA scores. Dec 31, 2015

Daily consumption of a powdered cranberry fruit lowered serum PSA in patients with prostate cancer. Nov 09, 2016

Dietary fiber intake might modulate the association between alcohol intake and risk of hormone dependent cancer.May 19, 2015

Dietary folate consumption as reflected in plasma folate and not supplementation with folic acid is inversely associated wtih prostate cancer risk. Mar 18, 2009

Dietary intakes of alpha and delta tocopherol were inversely associated with prostate cancer aggressiveness.Aug 31, 2015

Distribution of xenotropic murine leukemia virus-related virus (XMRV) infection in chronic fatigue syndrome and prostate cancer.Jun 30, 2010

Ellagic acid therapy reduces chemotherapy induced toxicity, e.g. neutropenia, in hormone refractory prostate cancer patients. Apr 01, 2005

Fish consumption is associated with a 63% reduction in prostate cancer-specific mortality.Nov 01, 2010

Fish consumption may improve prostate cancer survival rates.Nov 01, 2008

Flaxseed supplementation reduces prostate cancer proliferation rates in men presurgery. Dec 01, 2008

Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.Mar 31, 2013

Genistein and daidzein consumption are associated with a lower risk of prostate cancer. Aug 01, 2009

Genistein has therapeutic value in reducing PSA levels in men with prostate cancer. Feb 01, 2004

Genistein may block metastasis and mortality in prostate cancer through blocking the activation of MEK4 and MMP-2 expression. Aug 19, 2009

Green tea induced changes in NFκB and systemic oxidation, and uptake of GT polyphenols in prostate tissue they may have a role in prostate cancer prevention and treatment.Mar 31, 2015

Habitual mushroom intake might help to prevent prostate cancer.Sep 03, 2019

Higher concentrations of circulating genistein may reduce the risk of prostate cancer.Jun 02, 2009

Higher fruit intake was associated with a small reduction in prostate cancer risk.Apr 16, 2017

Higher levels of plasma carboxymethyllysine were associated with increased risk of prostate cancer.Sep 30, 2015

Higher vitamin E status increases overall prostate cancer survival. May 01, 2009

Hypermethylation of IFN and ICAM-1 may play important roles in early carcinogenesis, particularly that of prostate cancer.Aug 10, 2015

Increased exposure to sunlight may reduce prostate cancer risk. Sep 15, 2009

Individuals in the highest group of adherence to the Mediterranean diet had 78% less likelihood of having prostate cancer.Oct 17, 2018

Interventions with tomato-products alone or in combination with selenium and n-3 fatty acids lower PSA in patients with non-metastatic prostate cancer.Jun 29, 2016

Isoflavone-rich soy protein suppresses androgen receptor expression in men at high risk of prostate cancer. Jul 01, 2007

Lead toxicity may be associated with reproductive toxicity and prostate cancer intiation in men. Oct 01, 2007

Long-term supplementation with alpha-tocopherol (vitamin E) substantially reduced prostate cancer incidence and mortality in male smokers. Mar 18, 1998

Low blood Mg levels and a high Ca/Mg ratio were significantly associated with high-grade prostate cancer.Jan 01, 2011

Low vitamin D status is associated with inflammation in patients with prostate cancer.Mar 27, 2017

Lycopene and soy isoflavones have activity in prostate cancer patients with PSA relapse disease and may delay progression of both hormone-refractory and hormone-sensitive prostate cancer.Jul 01, 2009

Mass market multivitamin use is associated with a small increase in prostate cancer death rates. Aug 01, 2005

Mediterranean dietary pattern is associated to low risk of aggressive prostate cancer.Aug 21, 2017

Melatonin has been demonstrated to slow the proliferation of hormone-refractory prostate cancer in animal and human studies. Oct 01, 2003

Men with small prostates at the time of implant had a 33% higher risk of all-cause mortality. Apr 01, 2011

Modified Citrus Pectin increases the prostate-specific antigen (PSA) doubling time in men with prostate cancer. Jan 01, 2003

Occupational exposure to terbufos is associated with an increase in the incidence of cancer.Jun 01, 2010

Organochlorine pesticides may contribute to the initiation and pathogenesis of prostate cancer.Sep 01, 2010

Periodontitis might be associated with increased cancer risk.Jul 11, 2017

Phthalate exposure were associated with prostate cancer occurrence in abdominally obese men.Nov 07, 2019

Pomegranate juice prolongs PSA doubling time, inhibits cell proliferation and increases apoptosis in men with prostate cancer. Feb 01, 2007

POMx treatment significantly increased the PSA doubling time by over 6 months in both treatment arms.May 19, 2011

POMx treatment significantly increased the PSA doubling time by over 6 months in men with prostate cancer. Feb 28, 2011

Prostate Cancer

View the Evidence:
732 Abstracts with Prostate Cancer Research