Tinnitus

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9 Substances Researched for Tinnitus
NameACCKFocus
Ginkgo biloba544Locked
Melatonin330Locked
Zinc321Locked
Antioxidant formulas110Locked
Coenzyme Q10110Locked
Flavonoids110Locked
Ginseng (Korean)110Locked
Vitamin B-12110Locked
Spirulina24Locked
3 Problem Substances Researched for Tinnitus
NameACCKFocus
Cell Phone Exposure321Locked
Aspirin 59Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)47Locked
8 Therapeutic Actions Researched for Tinnitus
NameACCKFocus
Acupuncture670Locked
Electroacupuncture230Locked
Meditation 211Locked
Yoga211Locked
Laser Treatment: Low-Level110Locked
Mindfullness Training110Locked
Qigong110Locked
Sound Therapy110Locked
4 Problematic Actions Researched for Tinnitus
NameACCKFocus
Electromagnetic Field Harms541Locked
Electromagnetic Radiation541Locked
Microwave Radiation440Locked
Mobile Phone Radiation440Locked

View the Evidence:
40 Abstracts with Tinnitus Research

[+]

Manual and electrical acupuncture have therapeutic value in the treatment of tinnitus.Dec 01, 2010

Pubmed Data : Complement Ther Med. 2010 Dec;18(6):249-55. Epub 2010 Oct 8. PMID: 21130361
Article Published Date : Dec 01, 2010
Study Type : Meta Analysis
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Acupuncture, Electroacupuncture
[+]

There is evidence of efficacy for the Ginkgo biloba standardized extract, EGb 761, in the treatment of tinnitus. Jan 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2011 ;7:441-7. Epub 2011 Jul 28. PMID: 21857784
Article Published Date : Jan 01, 2011
Study Type : Meta Analysis
Additional Links
Substances : Ginkgo biloba
Diseases : Tinnitus
[+]

Acupuncture and continuous multi-point pulse stimulation treatment is effective in improving subjective symptoms of tinnitus.Dec 01, 2006

Pubmed Data : Zhongguo Zhen Jiu. 2006 Dec;26(12):859-62. PMID: 17313007
Article Published Date : Dec 01, 2006
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Acupuncture
[+]

This study indicates that tinnitus is associated with subjective electromagnetic hypersensitivity.Jan 01, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2009 ;4(3):e5026. Epub 2009 Mar 27. PMID: 19325894
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Additional Keywords : Electromagnetic Hypersensitivity, EMF
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation
[+]

10 Hz amplitude modulated sounds induce short-term tinnitus suppression.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2017 ;9:130. Epub 2017 May 19. PMID: 28579955
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Sound Therapy
[+]

Acupuncture has therapeutic activity in patients with tinnitus.Sep 01, 2007

Pubmed Data : Braz J Otorhinolaryngol. 2007 Sep-Oct;73(5):599-607. PMID: 18094800
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Acupuncture
[+]

Acupuncture has therapeutic value in the treatment of tinnitus.Apr 01, 2007

Pubmed Data : Zhongguo Zhen Jiu. 2007 Apr;27(4):249-51. PMID: 17585665
Article Published Date : Apr 01, 2007
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Acupuncture
[+]

Acupuncture is an effective treatment for patients with severe chronic subjective tinnitus.Jan 31, 2020

Pubmed Data : Med Acupunct. 2020 Feb 1 ;32(1):24-28. Epub 2020 Feb 3. PMID: 32104524
Article Published Date : Jan 31, 2020
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Acupuncture
[+]

Antoxidant therapy reduces symptoms in patients with idiopathic tinnitus. May 01, 2007

Pubmed Data : Arch Med Res. 2007 May;38(4):456-9. Epub 2007 Mar 12. PMID: 17416295
Article Published Date : May 01, 2007
Study Type : Human Study
Additional Links
Substances : Antioxidant formulas
Diseases : Tinnitus
[+]

Both the Nd:YAG and 810 nm diode lasers were effective for the treatment of subjective tinnitus related to temporomandibular joint disorders.Mar 13, 2017

Pubmed Data : Photomed Laser Surg. 2017 Mar 14. Epub 2017 Mar 14. PMID: 28294697
Article Published Date : Mar 13, 2017
Study Type : Human Study
Additional Links
Diseases : Temporomandibular Joint Disorders, Tinnitus
Therapeutic Actions : Laser Treatment: Low-Level
[+]

Chinese scalp acupuncture associated with bilateral electroacupuncture demonstrated a statistically significant improvement by reducing the level of tinnitus intensity.Nov 13, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Otorhinolaryngol. 2015 Nov 14. Epub 2015 Nov 14. PMID: 26654962
Article Published Date : Nov 13, 2015
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Acupuncture, Electroacupuncture
[+]

Coenzyme Q10 may decrease the symptoms of tinnitus in patients with low plasma Coenzyme Q10 levels. Jan 01, 2007

Pubmed Data : Otolaryngol Head Neck Surg. 2007 Jan;136(1):72-7. PMID: 17210337
Article Published Date : Jan 01, 2007
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Tinnitus
[+]

Ginkgo biloba improves the condition of patients with tinnitus. Article 1May 01, 2002

Pubmed Data : Int J Clin Pharmacol Ther. 2002 May;40(5):188-97. PMID: 12051570
Article Published Date : May 01, 2002
Study Type : Human Study
Additional Links
Substances : Ginkgo biloba
Diseases : Tinnitus
[+]

Ginkgo biloba improves the condition of patients with tinnitus. Article 2Sep 25, 1986

Pubmed Data : Presse Med. 1986 Sep 25;15(31):1562-4. PMID: 2947100
Article Published Date : Sep 25, 1986
Study Type : Human Study
Additional Links
Substances : Ginkgo biloba
Diseases : Tinnitus
[+]

Korean red ginseng may improve tinnitus symptoms and mental wellbeing in chronic tinnitus patients.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Audiol Otol. 2015 Sep ;19(2):85-90. Epub 2015 Sep 16. PMID: 26413574
Article Published Date : Aug 31, 2015
Study Type : Human Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Tinnitus
Additional Keywords : Significant Treatment Outcome
[+]

Melatonin is associated with a statistically significant decrease in tinnitus intensity and improved sleep quality in patients with chronic tinnitus.Jul 01, 2011

Pubmed Data : Ann Otol Rhinol Laryngol. 2011 Jul ;120(7):433-40. PMID: 21859051
Article Published Date : Jul 01, 2011
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Tinnitus
[+]

Melatonin may be a safe treatment for patients with idiopathic tinnitus. Article 1Feb 01, 2006

Pubmed Data : Otolaryngol Head Neck Surg. 2006 Feb;134(2):210-3. PMID: 16455366
Article Published Date : Feb 01, 2006
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Tinnitus
[+]

Melatonin may be a safe treatment for patients with idiopathic tinnitus. Article 2Mar 01, 1998

Pubmed Data : Laryngoscope. 1998 Mar;108(3):305-10. PMID: 9504599
Article Published Date : Mar 01, 1998
Study Type : Human Study
Additional Links
Substances : Melatonin
Diseases : Tinnitus
[+]

Mindfulness meditation therapy is effective in the management of tinnitus.Mar 29, 2017

Pubmed Data : J Laryngol Otol. 2017 Mar 30:1-7. Epub 2017 Mar 30. PMID: 28357966
Article Published Date : Mar 29, 2017
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Meditation , Mindfullness Training
[+]

Mobile phone use should be included in future investigations as a potential risk factor for developing tinnitus.Dec 01, 2010

Pubmed Data : Occup Environ Med. 2010 Dec ;67(12):804-8. Epub 2010 Jun 23. PMID: 20573849
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Additional Keywords : EMF
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation
[+]

Patients with tinnitus may have low blood zinc levels (31%) and clinical and subjective improvement can be achieved by oral zinc medication.Jan 01, 2003

Pubmed Data : Otol Neurotol. 2003 Jan;24(1):86-9. PMID: 12544035
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Substances : Zinc
Diseases : Tinnitus
[+]

Pycnogenol relieves symptoms of tinnitus by improving cochlear flow.Jun 01, 2010

Pubmed Data : Panminerva Med. 2010 Jun;52(2 Suppl 1):63-7. PMID: 20657537
Article Published Date : Jun 01, 2010
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Tinnitus
[+]

Qigong interventions could be a useful complement to the therapeutic management of patients with tinnitus and especially for those with somatosensoric components. Sep 01, 2010

Pubmed Data : J Psychosom Res. 2010 Sep;69(3):299-304. Epub 2010 Jun 11. PMID: 20708452
Article Published Date : Sep 01, 2010
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Qigong
[+]

Several factors related to mobile phone use are associated with tinnitus, depressed feelings, and sleepiness at school in adolescents.Oct 22, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health. 2013 Oct 22 ;12:90. Epub 2013 Oct 22. PMID: 24148357
Article Published Date : Oct 22, 2013
Study Type : Human Study
Additional Links
Diseases : Headaches, Tinnitus
Additional Keywords : Adolescent Development, Cell Phones, electromagnetic fields, electromagnetic frequencies, electromagnetic radiation, EMF, Radio Frequency Electromagnetic Radiation Exposure
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation
Problem Substances : Cell Phone Exposure
[+]

This study does not demonstrate a connection between predicted electromagnetic field exposure and tinnitus or non-specific symptoms.Jan 01, 2012

Pubmed Data : Environ Int. 2012 Jan ;38(1):29-36. Epub 2011 Sep 10. PMID: 21982030
Article Published Date : Jan 01, 2012
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Additional Keywords : EMF
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation
[+]

Vitamin B12 deficiency and its repletion may be useful in diagnosing and treating tinnitus. Mar 01, 1993

Pubmed Data : Am J Otolaryngol. 1993 Mar-Apr;14(2):94-9. PMID: 8484483
Article Published Date : Mar 01, 1993
Study Type : Human Study
Additional Links
Substances : Vitamin B-12
Diseases : Tinnitus
[+]

Yoga training has good potential to improve the daily functioning of patients with chronic tinnitus.Jul 31, 2019

Pubmed Data : Complement Ther Clin Pract. 2019 Aug ;36:7-11. Epub 2019 Apr 13. PMID: 31383447
Article Published Date : Jul 31, 2019
Study Type : Human Study
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Yoga
[+]

Zinc deficiency characterizes the serum of patients with tinnitus and repletion may be therapeutic. Sep 01, 1997

Pubmed Data : Nippon Jibiinkoka Gakkai Kaiho. 1997 Sep;100(9):915-9. PMID: 9339660
Article Published Date : Sep 01, 1997
Study Type : Human Study
Additional Links
Substances : Zinc
Diseases : Tinnitus
[+]

Altered expression of antioxidant genes may reflect states of oxidative stress associated with tinnitus.Aug 04, 2015

Pubmed Data : Audiol Neurootol. 2015 Aug 5 ;20(5):322-329. Epub 2015 Aug 5. PMID: 26277928
Article Published Date : Aug 04, 2015
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Oxidative Stress, Tinnitus
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Additional Keywords : Plant Extracts
[+]

Aspirin causes permanent reductions in neural activity in the cochlea and auditory brainstem response.Jun 14, 2010

Pubmed Data : Hear Res. 2010 Jun 14;265(1-2):63-9. Epub 2010 Mar 6. PMID: 20214971
Article Published Date : Jun 14, 2010
Study Type : Animal Study
Additional Links
Diseases : Hearing Loss, Tinnitus
Problem Substances : Aspirin
Adverse Pharmacological Actions : Neurotoxic
[+]

Ginkgo biloba attenuates salicylate-induced tinnitus in rats.Jul 01, 1997

Pubmed Data : Audiol Neurootol. 1997 Jul-Aug;2(4):197-212. PMID: 9390833
Article Published Date : Jul 01, 1997
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Aspirin-Induced Toxicity , Tinnitus
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Ginkgo biloba extract was beneficial for the treatment of existing noise induced hearing loss and tinnitus.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(6):e0157574. Epub 2016 Jun 17. PMID: 27315063
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Hearing Loss: Noise-Induced, Tinnitus
Additional Keywords : Plant Extracts
[+]

High doses of salicylate (aspirin) increase the gain of the central auditory system, presumably by down-regulating GABA-mediated inhibition, leading to an exaggerated acoustic startle response.Mar 03, 2009

Pubmed Data : Neuroscience. 2009 Mar 3;159(1):325-34. Epub 2008 Dec 24. PMID: 19154777
Article Published Date : Mar 03, 2009
Study Type : Animal Study
Additional Links
Diseases : Tinnitus
Problem Substances : Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Long-term administration of salicylate (aspirin) may adversely effect presin levels resulting in tinnitus.Jan 01, 2009

Pubmed Data : Int J Audiol. 2009 Jan;48(1):18-23. PMID: 19173110
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Hearing Loss, Tinnitus
Problem Substances : Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Neurotoxic
[+]

Spirulina could reduce salicylate-induced tinnitus.May 31, 2018

Pubmed Data : Int Tinnitus J. 2018 Jun 1 ;22(1):84-88. Epub 2018 Jun 1. PMID: 29993223
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Tinnitus
[+]

There is evidence that aspirin causing tinnitus in the rat model.Feb 17, 2010

Pubmed Data : Neuroscience. 2010 Feb 17;165(4):1323-32. Epub 2009 Dec 1. PMID: 19958810
Article Published Date : Feb 17, 2010
Study Type : Animal Study
Additional Links
Diseases : Hearing Loss, Tinnitus
Problem Substances : Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Neurotoxic
[+]

Effect of yoga and meditation on tinnitus: a systematic review.Mar 10, 2021

Pubmed Data : J Laryngol Otol. 2021 Mar 11:1-4. Epub 2021 Mar 11. PMID: 33691808
Article Published Date : Mar 10, 2021
Study Type : Review
Additional Links
Diseases : Tinnitus
Therapeutic Actions : Meditation , Yoga
[+]

Four among five small studies indicate that administration of zinc has a beneficial effect on tinnutis. Jan 01, 2007

Pubmed Data : Prog Brain Res. 2007;166:279-85. PMID: 17956792
Article Published Date : Jan 01, 2007
Study Type : Review
Additional Links
Substances : Zinc
Diseases : Tinnitus
[+]

The active ingredient in aspirin is sodium salicyclate which induces degeneration of cochlea spiral ganglion neurons. This may explain why aspirin use has been associated wtih Reye's syndrome, tinnitus and hearing loss.Jun 16, 2010

Pubmed Data : Neuroscience. 2010 Jun 16;168(1):288-99. Epub 2010 Mar 15. PMID: 20298761
Article Published Date : Jun 16, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Hearing Loss, Reye Syndrome, Tinnitus
Problem Substances : Aspirin , Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Neurotoxic
[+]

This review concludes that there is sufficient evidence to warrant cautionary use of mobile phones to prevent damage to the auditory pathway and the onset or worsening of tinnitus.Jan 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Otorhinolaryngol. 2016 Jan-Feb;82(1):97-104. Epub 2015 Sep 21. PMID: 26602000
Article Published Date : Jan 01, 2016
Study Type : Review
Additional Links
Diseases : Tinnitus
Additional Keywords : EMF
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Ototoxic

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