Focused Research Topics Pomegranate & Anti-Inflammatory Agents

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Associated Topics included in this Focused Research

Pomegranate Pomegranate Peel Pomegranate Polyphenols Pomegranate Seed Pomegranate flower

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104 Research Articles in Total

A Polyphenol-rich pomegranate fruit extract suppresses NF-κB and IL-6 expression.

Pubmed Data : Phytother Res. 2017 Mar 9. Epub 2017 Mar 9. PMID: 28276100
Article Published Date : Mar 08, 2017
Authors : Abdul Haseeb, Nazir M Khan, Omer S Ashruf, Tariq M Haqqi
Study Type : Human In Vitro
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Osteoarthritis : CK(1449) : AC(363)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Chondroprotective : CK(1) : AC(1), Interleukin-6 Downregulation : CK(5029) : AC(1994), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Concentrated pomegranate juice appeared to have favourable effects on certain markers of subclinical inflammation in diabetic patients.

Pubmed Data : Int J Endocrinol Metab. 2016 Jan ;14(1):e33835. Epub 2016 Jan 30. PMID: 27279834
Article Published Date : Dec 31, 2015
Authors : Farideh Shishehbor, Majid Mohammad Shahi, Mehdi Zarei, Azadeh Saki, Mehrnoosh Zakerkish, Fatemeh Shirani, Maryam Zare
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Diabetes Mellitus: Type 2 : CK(8552) : AC(1714), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Risk Reduction : CK(15144) : AC(1708)

Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis.

Pubmed Data : Isr Med Assoc J. 2011 Aug ;13(8):474-9. PMID: 21910371
Article Published Date : Aug 01, 2011
Authors : Alexandra Balbir-Gurman, Bianca Fuhrman, Yolanda Braun-Moscovici, Doron Markovits, Michael Aviram
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Lipid Peroxidation : CK(1632) : AC(631), Rheumatoid Arthritis : CK(1546) : AC(328)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Evaluation of wound healing potential of pomegranate whole fruit extract on skin burn wounds.

Pubmed Data : J Adv Vet Anim Res. 2019 Jun ;6(2):202-207. Epub 2019 Apr 14. PMID: 31453192
Article Published Date : May 31, 2019
Authors : Bambang Sektiari Lukiswanto, Alya Miranti, Sri Agus Sudjarwo, Hardany Primarizky, Wiwik Misaco Yuniarti
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Burns : CK(248) : AC(76), Wound Healing : CK(1362) : AC(477)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251), Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Hepatoprotective potential of pomegranate in curbing the incidence of acute liver injury.

Pubmed Data : Front Pharmacol. 2021 ;12:694607. Epub 2021 Nov 26. PMID: 34899284
Article Published Date : Dec 31, 2020
Authors : Hamid Ali, Azra Jahan, Samrana Samrana, Abid Ali, Safdar Ali, Nurul Kabir, Amjad Ali, Riaz Ullah, Ramzi A Mothana, Bibi Nazia Murtaza, Muhammad Kalim
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Hepatitis : CK(130) : AC(52), Liver Damage : CK(2494) : AC(1121)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264)

Polyherbal combination for wound healing: Matricaria chamomilla L. and Punica granatum L.

Pubmed Data : Daru. 2021 May 9. Epub 2021 May 9. PMID: 33966255
Article Published Date : May 08, 2021
Authors : Somayeh Niknam, Zahra Tofighi, Mohammad Ali Faramarzi, Mohammad Amin Abdollahifar, Ensieh Sajadi, Rassoul Dinarvand, Tayebeh Toliyat
Study Type : Animal Study
Additional Links
Substances : Chamomile : CK(572) : AC(111), Pomegranate : CK(1222) : AC(405)
Diseases : Wound Healing : CK(1362) : AC(477)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Polyphenols on the outcomes of inflammatory factors and oxidative stress in patients with type 2 diabetes mellitus.

Pubmed Data : Rev Cardiovasc Med. 2022 Feb 11 ;23(2):57. PMID: 35229548
Article Published Date : Feb 10, 2022
Authors : Milkica Grabež, Ranko Škrbić, Miloš P Stojiljković, Vesna Vučić, Vesna Rudić Grujić, Vladimir Jakovljević, Dragan M Djuric, Relja Suručić, Katarina Šavikin, Dubravka Bigović, Nađa Vasiljević
Study Type : Human Study
Additional Links
Substances : Polyphenols : CK(1878) : AC(700), Pomegranate Peel : CK(117) : AC(62)
Diseases : Diabetes: Oxidative Stress : CK(492) : AC(182), Diabetes Mellitus: Type 2 : CK(8552) : AC(1714)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Pomanox supplementation hinders hyperlipemia-induced coronary endothelial dysfunction by activating the Akt/endothelial nitric oxide-synthase pathway

Pubmed Data : Rev Esp Cardiol (Engl Ed). 2015 Mar ;68(3):216-25. Epub 2014 Oct 23. PMID: 25444379
Article Published Date : Feb 28, 2015
Authors : Gemma Vilahur, Teresa Padró, Laura Casaní, Guiomar Mendieta, José A López, Sergio Streitenberger, Lina Badimon
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405), Pomegranate Polyphenols : CK(20) : AC(9)
Diseases : Endothelial Dysfunction : CK(2115) : AC(440), Oxidative Stress : CK(9437) : AC(3550)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Vasoprotective : CK(207) : AC(52)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Pomegranate as a possible treatment in reducing risk of developing wound healing, obesity, neurodegenerative disorders, and diabetes mellitus.

Pubmed Data : Mini Rev Med Chem. 2017 Apr 19. Epub 2017 Apr 19. PMID: 28425868
Article Published Date : Apr 18, 2017
Authors : Manaf AlMatar, Md Rashedul Islam, Othman Albari, Işıl Var, Fatih Köksal
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Pomegranate : CK(1222) : AC(405), Neurodegenerative Diseases : CK(8689) : AC(2653), Obesity : CK(6879) : AC(1686), Wound Healing : CK(1362) : AC(477)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Pomegranate can be used as a dietary supplement in the treatment of cisplatin-induced kidney injury.

Pubmed Data : Food Funct. 2016 Jun 7. Epub 2016 Jun 7. PMID: 27273121
Article Published Date : Jun 06, 2016
Authors : Ritu Karwasra, Prerna Kalra, Yogendra Kumar Gupta, Deepika Saini, Ajay Kumar, Surender Singh
Study Type : Animal Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : Chemotherapy-Induced Toxicity: Cisplatin : CK(881) : AC(388)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Chemoprotective Agents : CK(2322) : AC(906), Renoprotective : CK(2404) : AC(1075)

Pomegranate could be a potential and efficacious therapeutic agent against liver fibrosis.

Pubmed Data : Sci Rep. 2018 Jun 5 ;8(1):8606. Epub 2018 Jun 5. PMID: 29872102
Article Published Date : Jun 04, 2018
Authors : Hadiya Husain, Uzma Latief, Riaz Ahmad
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Liver Fibrosis : CK(560) : AC(253)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264)

Pomegranate exerts hepatoprotective effects against CCl4 induced oxidative stress and liver tissue damage.

Pubmed Data : Mol Med Rep. 2016 Mar 1. Epub 2016 Mar 1. PMID: 26936425
Article Published Date : Feb 29, 2016
Authors : Zein Shaban Ibrahim, Mohamed Abdo Nassan, Mohamed Mohamed Soliman
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Chemically-Induced Liver Damage : CK(1565) : AC(721)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264), Regenerative : CK(408) : AC(172)

Pomegranate extract improves colitis in IL-10 knockout mice fed a high fat high sucrose diet.

Pubmed Data : Mol Nutr Food Res. 2021 Dec 21:e2100730. Epub 2021 Dec 21. PMID: 34932869
Article Published Date : Dec 20, 2021
Authors : Jieping Yang, Patrizia Maria Germano, Suwan Oh, Sijia Wang, Jing Wang, Rupo Lee, Hayden Paige, Scarlet Yang, Susanne M Henning, Jin Zhong, Jonathan P Jacobs, Zhaoping Li
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Colitis : CK(840) : AC(406), High Fat Diet : CK(1267) : AC(602), High Sugar Diet : CK(313) : AC(80)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Pomegranate extracts and exercise may be additively effective in improving immune function in HFD-fed rats.

Pubmed Data : J Nutr Biochem. 2016 Feb 28 ;32:20-28. Epub 2016 Feb 28. PMID: 27142733
Article Published Date : Feb 27, 2016
Authors : Fei Zhao, Wentao Pang, Ziyi Zhang, Jialong Zhao, Xin Wang, Ye Liu, Xun Wang, Zhihui Feng, Yong Zhang, Wenyan Sun, Jiankang Liu
Study Type : Animal Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : High Fat Diet : CK(1267) : AC(602), Inflammation : CK(9572) : AC(3089), Oxidative Stress : CK(9437) : AC(3550)
Therapeutic Actions : Exercise : CK(4855) : AC(736), Integrative Medicine : CK(501) : AC(69)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Pomegranate is promising in development a functional biomolecule in treatment and protection against diabetic complications as nephropathy.

Pubmed Data : Environ Sci Pollut Res Int. 2022 Oct 3. Epub 2022 Oct 3. PMID: 36190633
Article Published Date : Oct 02, 2022
Authors : Rami M Mosaoa, Soonham S Yaghmoor, Said S Moselhy
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870), Pomegranate : CK(1222) : AC(405)
Diseases : Diabetic Nephropathy : CK(707) : AC(277)
Pharmacological Actions : Anti-Glycation Agents : CK(197) : AC(100), Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Pomegranate juice attenuated the damaging effects of cigarette smoke on cultured human alveolar cells.

Pubmed Data : Int J Chron Obstruct Pulmon Dis. 2016 ;11:227-37. Epub 2016 Feb 3. PMID: 26893554
Article Published Date : Dec 31, 2015
Authors : Ahmad Husari, Yasmine Hashem, Hala Bitar, Ghassan Dbaibo, Ghazi Zaatari, Marwan El Sabban
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Inflammation : CK(9572) : AC(3089), Lung Injury: Smoke-Induced : CK(71) : AC(33)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Pomegranate juice can prevent NAFLD even in the presence of the other risk factors.

Pubmed Data : J Sci Food Agric. 2016 Sep 22. Epub 2016 Aug 22. PMID: 27717115
Article Published Date : Sep 21, 2016
Authors : Maryam Noori, Bahar Jafari, Azita Hekmatdoost
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Prophylactic Agents : CK(780) : AC(182)
Additional Keywords : Risk Reduction : CK(15144) : AC(1708)

Pomegranate juice concentrated powder has favourable protective effects against UVB-induced photoaging through anti-apoptotic effects.

Pubmed Data : Exp Ther Med. 2017 Aug ;14(2):1023-1036. Epub 2017 Jun 16. PMID: 28810554
Article Published Date : Jul 31, 2017
Authors : Su-Jin Kang, Beom-Rak Choi, Seung-Hee Kim, Hae-Yeon Yi, Hye-Rim Park, Chang-Hyun Song, Sae-Kwang Ku, Young-Joon Lee
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Ultraviolet Radiation Induced Damage : CK(461) : AC(215)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Photoprotective : CK(446) : AC(198)

Pomegranate juice consumption has potential anti-inflammatory and cardio-protective effects.

Pubmed Data : J Sci Food Agric. 2016 Aug 1. Epub 2016 Aug 1. PMID: 27476699
Article Published Date : Jul 31, 2016
Authors : Milica I Kojadinovic, Aleksandra C Arsic, Jasmina D Debeljak-Martacic, Aleksandra I Konic-Ristic, Nevena Dj Kardum, Tamara B Popovic, Marija D Glibetic
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Lipid Peroxidation : CK(1632) : AC(631), Metabolic Diseases : CK(828) : AC(178)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Cardioprotective : CK(5377) : AC(1675), Malondialdehyde Down-regulation : CK(2065) : AC(678)

Pomegranate juice extract ameliorated polycystic ovary syndrome accompanying endometrial histological alterations.

Pubmed Data : Morphologie. 2021 May 19. Epub 2021 May 19. PMID: 34023214
Article Published Date : May 18, 2021
Authors : M A A Ibrahim, M T Sadek, H E M Sharaf Eldin
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Polycystic Ovary Syndrome : CK(1093) : AC(163)
Pharmacological Actions : Anti-Fibrotic : CK(924) : AC(463), Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Antiproliferative : CK(6801) : AC(5032)

Pomegranate juice improves the cardiometabolic risk factors, biomarkers of oxidative stress and inflammation in hemodialysis patients.

Pubmed Data : J Sci Food Agric. 2019 Oct 23. Epub 2019 Oct 23. PMID: 31646650
Article Published Date : Oct 22, 2019
Authors : Reza Barati Boldaji, Zahra Esmaeilinezhad, Mohammad Mahdi Sagheb, Masoumeh Akhlaghi
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Hemodialysis : CK(950) : AC(99)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Interleukin-6 Downregulation : CK(5029) : AC(1994), Malondialdehyde Down-regulation : CK(2065) : AC(678)

Pomegranate juice was proved to be a potential hepato-renal protective agent against liver and kidney damage induced by copper oxide nanoparticles.

Pubmed Data : Int J Nanomedicine. 2019 ;14:8905-8922. Epub 2019 Nov 15. PMID: 31814719
Article Published Date : Dec 31, 2018
Authors : Eman I Hassanen, A F Tohamy, Marwa Y Issa, Marwa A Ibrahim, Khaled Y Farroh, Azza M Hassan
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Chemically-Induced Liver Damage : CK(1565) : AC(721), Kidney Damage : CK(458) : AC(200)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264), Renoprotective : CK(2404) : AC(1075)
Problem Substances : Copper Oxide : CK(21) : AC(9)

Pomegranate oil's potential as an anti-obesity ingredient.

Pubmed Data : Molecules. 2022 Aug 4 ;27(15). Epub 2022 Aug 4. PMID: 35956908
Article Published Date : Aug 03, 2022
Authors : Manuela Machado, Eduardo M Costa, Sara Silva, Luís M Rodriguez-Alcalá, Ana M Gomes, Manuela Pintado
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Interleukin-6 Downregulation : CK(5029) : AC(1994), Interleukin-8 downregulation : CK(581) : AC(231), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Anti-Obesity Agents : CK(2925) : AC(774)

Pomegranate peel extract and punicalagin may be useful in alleviating inflammatory reactions due to particulate matter.

Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:6836080. Epub 2016 May 10. PMID: 27247608
Article Published Date : Dec 31, 2015
Authors : Soojin Park, Jin Kyung Seok, Jun Yup Kwak, Hwa-Jin Suh, Young Mi Kim, Yong Chool Boo
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62), Punicalagin : CK(127) : AC(78)
Diseases : Air Pollution Linked Toxicity : CK(2859) : AC(425)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Pomegranate protects liver against cecal ligation and puncture-induced oxidative stress and inflammation in rats.

Pubmed Data : Environ Toxicol Pharmacol. 2016 Mar 15 ;43:182-192. Epub 2016 Mar 15. PMID: 27011232
Article Published Date : Mar 14, 2016
Authors : Mirhan N Makled, Mohammed S El-Awady, Rania R Abdelaziz, Nadia Atwan, Emma T Guns, Nariman M Gameil, Ahmed B Shehab El-Din, Elsayed M Ammar
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Lipid Peroxidation : CK(1632) : AC(631), Liver Damage : CK(2494) : AC(1121), Sepsis : CK(952) : AC(276)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264), Malondialdehyde Down-regulation : CK(2065) : AC(678), NF-kappaB Inhibitor : CK(3536) : AC(2098)

Pomegranate seed oil demonstrated an important therapeutic effect in the treatment of ovarian ischemia and reperfusion injury.

Pubmed Data : Iran J Basic Med Sci. 2018 Dec ;21(12):1262-1268. PMID: 30627370
Article Published Date : Nov 30, 2018
Authors : Muhammed Yayla, Damla Cetin, Yasemen Adali, Pinar Aksu Kilicle, Erdem Toktay
Study Type : Animal Study
Additional Links
Substances : Pomegranate Seed : CK(35) : AC(15)
Diseases : Ischemia : CK(392) : AC(198)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

POMx alleviates disease activity and improves some blood biomarkers of inflammation and oxidative stress in rheumatoid arthritis patients.

Pubmed Data : Eur J Clin Nutr. 2016 Aug 31. Epub 2016 Aug 31. PMID: 27577177
Article Published Date : Aug 30, 2016
Authors : M Ghavipour, G Sotoudeh, E Tavakoli, K Mowla, J Hasanzadeh, Z Mazloom
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Rheumatoid Arthritis : CK(1546) : AC(328)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Potential effects of pomegranate on rheumatoid arthritis.

Pubmed Data : Int J Clin Pract. 2021 Jan 5:e13999. Epub 2021 Jan 5. PMID: 33400368
Article Published Date : Jan 04, 2021
Authors : Aida Malek Mahdavi, Neda Seyedsadjadi, Zeinab Javadivala
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Rheumatoid Arthritis : CK(1546) : AC(328)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Protective effect of pomegranate on oxidative stress and inflammatory response induced by 5-fluorouracil in human keratinocytes.

Pubmed Data : Antioxidants (Basel). 2021 Jan 30 ;10(2). Epub 2021 Jan 30. PMID: 33573363
Article Published Date : Jan 29, 2021
Authors : Shara Francesca Rapa, Giorgia Magliocca, Giacomo Pepe, Giuseppina Amodio, Giuseppina Autore, Pietro Campiglia, Stefania Marzocco
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Chemotherapy-Induced Toxicity: 5-fluorouracil : CK(91) : AC(40)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Chemoprotective Agents : CK(2322) : AC(906)

Punica granatum peel extract pre-treatment alleviates fenpropathrin-induced testicular injury.

Pubmed Data : Toxics. 2023 Jun 3 ;11(6). Epub 2023 Jun 3. PMID: 37368604
Article Published Date : Jun 02, 2023
Authors : Ali B Jebur, Raghda A El-Sayed, Mohamed M Abdel-Daim, Fatma M El-Demerdash
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Testicular Injury: Chemical/Metal Induced : CK(340) : AC(174)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856)

Systematic review of the effects of pomegranate ( Punica granatum) on osteoarthritis.

Pubmed Data : Health Promot Perspect. 2021 ;11(4):411-425. Epub 2021 Dec 19. PMID: 35079584
Article Published Date : Dec 31, 2020
Authors : Aida Malek Mahdavi, Zeinab Javadivala
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Osteoarthritis : CK(1449) : AC(363)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Osteoprotective : CK(971) : AC(351)

The efficiency of pomegranate peel ethanolic extract in attenuating the vancomycin-triggered liver and kidney tissues injury.

Pubmed Data : Environ Sci Pollut Res Int. 2020 Oct 7. Epub 2020 Oct 7. PMID: 33029776
Article Published Date : Oct 06, 2020
Authors : Khlood M El Bohi, Sabry M Abdel-Motal, Samah R Khalil, Mayar Mahmoud Abd-Elaal, Mohamed M M Metwally, Walaa M ELhady
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Chemically-Induced Liver Damage : CK(1565) : AC(721), Chemotherapy-Induced Kidney Damage : CK(98) : AC(44)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264), Renoprotective : CK(2404) : AC(1075)

These findings suggest that the methanolic leaf extract of Punica granatum possesses significant cerebroprotective activity.

Pubmed Data : Iran J Basic Med Sci. 2019 Feb ;22(2):187-196. PMID: 30834085
Article Published Date : Jan 31, 2019
Authors : Gollapalle Lakshminarayanashastry Viswanatha, Marikunte Venkatanarasappa Venkataranganna, Nunna Bheema Lingeswara Prasad
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Cerebral Ischemia : CK(670) : AC(304)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Antioxidants : CK(21528) : AC(8856), Neuroprotective Agents : CK(10404) : AC(4396)

A herbal mixture from propolis, pomegranate, and grape pomace endowed with anti-inflammatory activity in an in vivo rheumatoid arthritis model.

Pubmed Data : Molecules. 2020 May 11 ;25(9). Epub 2020 May 11. PMID: 32403241
Article Published Date : May 10, 2020
Authors : Valentina Parisi, Antonio Vassallo, Claudio Pisano, Giacomo Signorino, Francesco Cardile, Milena Sorrentino, Fabiana Colelli, Alessandra Fucci, Egildo Luca D'Andrea, Nunziatina De Tommasi, Alessandra Braca, Marinella De Leo
Study Type : Animal Study
Additional Links
Substances : Grape : CK(4560) : AC(1322), Pomegranate : CK(1222) : AC(405), Propolis: Bee : CK(138) : AC(50)
Diseases : Rheumatoid Arthritis : CK(1546) : AC(328)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-17 downregulation : CK(193) : AC(85), Interleukin-1 beta downregulation : CK(3041) : AC(1567)

A variety of natural substances have preventive potential in osteoarthritis and rheumatoid arthritis.

Pubmed Data : Arthritis Res Ther. 2011 Feb 3;13(1):102. Epub 2011 Feb 3. PMID: 21345249
Article Published Date : Feb 03, 2011
Authors : Sarah Khalifé, Muhammad Zafarullah
Study Type : Review
Additional Links
Substances : Curcumin : CK(5598) : AC(2788), EGCG (Epigallocatechin gallate) : CK(1091) : AC(605), Pomegranate : CK(1222) : AC(405), Resveratrol : CK(2037) : AC(1112)
Diseases : Osteoarthritis : CK(1449) : AC(363), Rheumatoid Arthritis : CK(1546) : AC(328)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Crosstalk between dietary pomegranate and gut microbiota: evidence of health benefits.

Pubmed Data : Crit Rev Food Sci Nutr. 2023 Jun 19:1-27. Epub 2023 Jun 19. PMID: 37335106
Article Published Date : Jun 18, 2023
Authors : Yantao Yin, Remigio Martínez, Wangang Zhang, Mario Estévez
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Dysbiosis : CK(1527) : AC(422)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Gastrointestinal Agents : CK(3145) : AC(843)

Effects of pomegranate peel polyphenols combined with inulin on gut microbiota and serum metabolites of high-fat-induced obesity.

Pubmed Data : J Agric Food Chem. 2023 Apr 12 ;71(14):5733-5744. Epub 2023 Mar 30. PMID: 36996454
Article Published Date : Apr 11, 2023
Authors : Haidan Shi, Xuezhi Li, Chen Hou, Li Chen, Yuhuan Zhang, Jianke Li
Study Type : Animal Study
Additional Links
Substances : Polyphenols : CK(1878) : AC(700), Pomegranate Peel : CK(117) : AC(62)
Diseases : High Fat Diet : CK(1267) : AC(602), Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Extracts rich in gallo- and ellagitannins act on different molecular targets in the protection against ulcerative colitis.

Pubmed Data : Mol Nutr Food Res. 2016 Mar 29. Epub 2016 Mar 29. PMID: 27028006
Article Published Date : Mar 28, 2016
Authors : Hyemee Kim, Nivedita Banerjee, Ivan Ivanov, Catherine M Pfent, Kalan R Prudhomme, William H Bisson, Rodrick H Dashwood, Stephen T Talcott, Susanne U Mertens-Talcott
Study Type : Animal Study
Additional Links
Substances : Mango : CK(395) : AC(200), Pomegranate : CK(1222) : AC(405)
Diseases : Ulcerative Colitis : CK(666) : AC(196)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Functional foods modulating inflammation and metabolism in chronic diseases.

Pubmed Data : Crit Rev Food Sci Nutr. 2021 Jan 28:1-22. Epub 2021 Jan 28. PMID: 33506690
Article Published Date : Jan 27, 2021
Authors : Julissa Luvián-Morales, Francisco Omar Varela-Castillo, Laura Flores-Cisneros, Lucely Cetina-Pérez, Denisse Castro-Eguiluz
Study Type : Review
Additional Links
Substances : Cardamom : CK(42) : AC(11), Chia : CK(144) : AC(42), Cranberry : CK(564) : AC(121), Flaxseed : CK(902) : AC(174), Grape : CK(4560) : AC(1322), Green Tea : CK(3450) : AC(1057), Pistachio nut : CK(182) : AC(35), Pomegranate : CK(1222) : AC(405), Strawberry : CK(384) : AC(112), Yoghurt : CK(1014) : AC(135)
Diseases : Chronic Disease : CK(84) : AC(10), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Healthy properties of a new formulation of pomegranate-peel extract in mice suffering from experimental autoimmune encephalomyelitis.

Pubmed Data : Molecules. 2022 Jan 28 ;27(3). Epub 2022 Jan 28. PMID: 35164175
Article Published Date : Jan 27, 2022
Authors : Giulia Vallarino, Annalisa Salis, Elena Lucarini, Federica Turrini, Guendalina Olivero, Alessandra Roggeri, Gianluca Damonte, Raffaella Boggia, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Anna Pittaluga
Study Type : Animal Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : Encephalomyelitis : CK(100) : AC(50), Multiple Sclerosis : CK(1802) : AC(394)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Neuroprotective Agents : CK(10404) : AC(4396)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

High-dose berberine ameliorated cigarette smoke extract-induced airway inflammation in COPD mice.

Pubmed Data : Curr Med Sci. 2019 Oct ;39(5):748-753. Epub 2019 Oct 14. PMID: 31612392
Article Published Date : Sep 30, 2019
Authors : Wen Wang, Gan Zha, Jin-Jing Zou, Xun Wang, Chun-Nian Li, Xiao-Jun Wu
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Chronic Obstructive Pulmonary Disease : CK(1007) : AC(158), Lung Injury: Smoke-Induced : CK(71) : AC(33)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Human volunteers treated with pomegranate seed oil showed substantial amelioration of skin inflammation.

Pubmed Data : Molecules. 2023 Jan 16 ;28(2). Epub 2023 Jan 16. PMID: 36677961
Article Published Date : Jan 15, 2023
Authors : Asmaa Fathi Hamouda, Shifa Felemban
Study Type : Human Study
Additional Links
Substances : Pomegranate Seed : CK(35) : AC(15)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Intake of pomegranate prevents the onset of osteoarthritis

Pubmed Data : Int J Health Sci (Qassim). 2016 Apr ;10(2):V-VIII. PMID: 27103912
Article Published Date : Mar 31, 2016
Authors : Zafar Rasheed
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Osteoarthritis : CK(1449) : AC(363)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Prophylactic Agents : CK(780) : AC(182)
Additional Keywords : Gene Expression Regulation : CK(1141) : AC(501)

Maternal pomegranate juice attenuates maternal inflammation-induced fetal brain injury.

Pubmed Data : Am J Obstet Gynecol. 2018 Apr 27. Epub 2018 Apr 27. PMID: 29709511
Article Published Date : Apr 26, 2018
Authors : Yuval Ginsberg, Nizar Khatib, Noor Saadi, Michael G Ross, Zeev Weinr, Ron Beloosesky
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Fetal Origin of Adult Disease : CK(246) : AC(60), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Neuroprotective Agents : CK(10404) : AC(4396), NF-kappaB Inhibitor : CK(3536) : AC(2098)

Optimized curcumin, pomegranate extract, and methylsulfonylmethane reduce acute, systemic inflammatory response to a half-marathon race.

Pubmed Data : Altern Ther Health Med. 2020 Jul 1. Epub 2020 Jul 1. PMID: 32619204
Article Published Date : Jun 30, 2020
Authors : Elizabeth A Tanner, Melody A Gary, Stephan Michalik, Asheal A Davis, Brian K McFarlin
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(5598) : AC(2788), MSM (Methylsulfonylmethane) : CK(137) : AC(33), Pomegranate : CK(1222) : AC(405)
Diseases : Inflammation : CK(9572) : AC(3089), Muscle Damage: Exercise-Induced : CK(570) : AC(68)
Therapeutic Actions : Exercise: Running : CK(342) : AC(43)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Polyphenol and methylsulfonylmethane supplementation improves immune, DAMP signaling, and inflammatory responses during recovery from all-out running efforts.

Pubmed Data : Front Physiol. 2021 ;12:712731. Epub 2021 Aug 31. PMID: 34531760
Article Published Date : Dec 31, 2020
Authors : Brian K McFarlin, David W Hill, Jakob L Vingren, John H Curtis, Elizabeth A Tanner
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(5598) : AC(2788), MSM (Methylsulfonylmethane) : CK(137) : AC(33), Polyphenols : CK(1878) : AC(700), Pomegranate Polyphenols : CK(20) : AC(9)
Diseases : Inflammation : CK(9572) : AC(3089)
Therapeutic Actions : Exercise: Running : CK(342) : AC(43)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Polyphenols potentiate dietary restriction-induced lifespan extension.

Pubmed Data : Biochim Biophys Acta. 2012 Jan 11 ;1822(4):522-526. Epub 2012 Jan 11. PMID: 22265987
Article Published Date : Jan 11, 2012
Authors : Daniel J Aires, Graham Rockwell, Ting Wang, Jennifer Frontera, Jo Wick, Wenfang Wang, Marija Tonkovic-Capin, Jianghua Lu, Lezi E, Hao Zhu, Russell H Swerdlow
Study Type : Animal Study
Additional Links
Substances : Blueberry : CK(721) : AC(250), Green Tea : CK(3450) : AC(1057), Polyphenols : CK(1878) : AC(700), Pomegranate : CK(1222) : AC(405)
Diseases : Aging : CK(3728) : AC(933)
Therapeutic Actions : Fasting/Caloric Restriction : CK(449) : AC(108)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Pomegranate attenuates neuroinflammation involved in neurodegenerative diseases.

Pubmed Data : Foods. 2022 Aug 25 ;11(17). Epub 2022 Aug 25. PMID: 36076756
Article Published Date : Aug 24, 2022
Authors : Alami Mehdi, Benchagra Lamiae, Boulbaroud Samira, Mhamed Ramchoun, Khalil Abdelouahed, Fulop Tamas, Berrougui Hicham
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Neurodegenerative Diseases : CK(8689) : AC(2653)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Neuroprotective Agents : CK(10404) : AC(4396)

Pomegranate by-products could be used in colorectal cancer chemoprevention.

Pubmed Data : Mol Nutr Food Res. 2017 Sep 25. Epub 2017 Sep 25. PMID: 28948694
Article Published Date : Sep 24, 2017
Authors : Katia Tortora, Angelo Pietro Femia, Andrea Romagnoli, Irene Sineo, Mohamad Khatib, Nadia Mulinacci, Lisa Giovannelli, Giovanna Caderni
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Colorectal Cancer : CK(3666) : AC(1651)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Apoptotic : CK(6986) : AC(5304), Chemopreventive : CK(5374) : AC(1717), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926)

Pomegranate extract affects gut biofilm forming bacteria and promotes intestinal mucosal healing.

Pubmed Data : Nutrients. 2023 Apr 5 ;15(7). Epub 2023 Apr 5. PMID: 37049615
Article Published Date : Apr 04, 2023
Authors : Giulia Rizzo, Samuel Elias Pineda Chavez, Elisa Vandenkoornhuyse, Cindy Lorena Cárdenas Rincón, Valeria Cento, Valentina Garlatti, Marek Wozny, Giusy Sammarco, Alessia Di Claudio, Lisa Meanti, Sudharshan Elangovan, Andrea Romano, Giulia Roda, Laura Loy, Arianna Dal Buono, Roberto Gabbiadini, Sara Lovisa, Roberto Rusconi, Alessandro Repici, Alessandro Armuzzi, Stefania Vetrano
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Colitis : CK(840) : AC(406), Inflammatory Bowel Diseases : CK(1994) : AC(540), Wound Healing : CK(1362) : AC(477)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Gastrointestinal Agents : CK(3145) : AC(843), Interleukin-6 Downregulation : CK(5029) : AC(1994), Interleukin-8 downregulation : CK(581) : AC(231)

Pomegranate extract consumption may reduce complications linked with obesity.

Pubmed Data : Complement Ther Clin Pract. 2016 Feb ;22:44-50. Epub 2015 Dec 12. PMID: 26850805
Article Published Date : Jan 31, 2016
Authors : Banafshe Hosseini, Ahmad Saedisomeolia, Lisa G Wood, Mehdi Yaseri, Sanaz Tavasoli
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hypoglycemic Agents : CK(5366) : AC(1338), Hypolipidemic : CK(5358) : AC(1221)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Pomegranate extract improves several markers of NAFLD.

Pubmed Data : Diabetes Metab Syndr. 2022 Dec 13 ;17(1):102693. Epub 2022 Dec 13. PMID: 36535123
Article Published Date : Dec 12, 2022
Authors : Sima Jafarirad, Reza Goodarzi, Narges Mohammadtaghvaei, Maryam Dastoorpoor, Pejman Alavinejad
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hepatoprotective : CK(5098) : AC(2264), Interleukin-6 Downregulation : CK(5029) : AC(1994)

Pomegranate extract is abundant in hydrolysable tannins that display multiple anti-acne capacities.

Pubmed Data : Int J Mol Sci. 2017 Jan 12 ;18(1). Epub 2017 Jan 12. PMID: 28085116
Article Published Date : Jan 11, 2017
Authors : Chia-Jung Lee, Lih-Geeng Chen, Wen-Li Liang, Ching-Chiung Wang
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Acne : CK(544) : AC(95)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251), Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Prostaglandin PGE2 downregulation : CK(193) : AC(88)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

pomegranate extract merits further investigation as a complementary approach to alleviate obesity, reducing the low grade of chronic inflammation and metabolic stress.

Pubmed Data : Int J Mol Sci. 2022 Sep 9 ;23(18). Epub 2022 Sep 9. PMID: 36142372
Article Published Date : Sep 08, 2022
Authors : Marina Reguero, Marta Gómez de Cedrón, Aranzazu Sierra-Ramírez, Pablo José Fernández-Marcos, Guillermo Reglero, José Carlos Quintela, Ana Ramírez de Molina
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : High Fat Diet : CK(1267) : AC(602), Inflammation : CK(9572) : AC(3089), Insulin Resistance : CK(3522) : AC(792), Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Pomegranate inhibits inflammation, as well as amyloidogenesis in IL-1β-stimulated SK-N-SH cells.

Pubmed Data : Eur J Nutr. 2015 Jul 10. Epub 2015 Jul 10. PMID: 26155780
Article Published Date : Jul 09, 2015
Authors : Ravikanth Velagapudi, Gina Baco, Sunjeet Khela, Uchechukwu Okorji, Olumayokun Olajide
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Alzheimer's Disease : CK(3372) : AC(1307), Brain Inflammation : CK(1101) : AC(567), Neurodegenerative Diseases : CK(8689) : AC(2653)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), NF-kappaB Inhibitor : CK(3536) : AC(2098)

Pomegranate juice can be potentially used for the treatment of inflammatory bowel disease.

Pubmed Data : Mol Cell Biochem. 2016 Jun 28. Epub 2016 Jun 28. PMID: 27352379
Article Published Date : Jun 27, 2016
Authors : Tanmay A Shah, Mihir Parikh, Kirti V Patel, Kalpana G Patel, Chaitanya G Joshi, Tejal R Gandhi
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Inflammatory Bowel Diseases : CK(1994) : AC(540)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-18 down-regulation : CK(132) : AC(61), Interleukin-1 beta downregulation : CK(3041) : AC(1567), NF-kappaB Inhibitor : CK(3536) : AC(2098), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Pomegranate juice fermented by tannin acyl hydrolase and Lactobacillus vespulae DCY75 enhance estrogen receptor expression and anti-inflammatory effect.

Pubmed Data : Front Pharmacol. 2022 ;13:1010103. Epub 2022 Sep 29. PMID: 36249796
Article Published Date : Dec 31, 2021
Authors : Reshmi Akter, Jong Chan Ahn, Jinnatun Nahar, Muhammad Awais, Zelika Mega Ramadhania, Se-Woung Oh, Ji-Hyung Oh, Byoung Man Kong, Esrat Jahan Rupa, Dong Wong Lee, Deok Chun Yang, Se Chan Kang
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages : CK(2588) : AC(607), Lactobacillus probiotics : CK(4208) : AC(791), Pomegranate : CK(1222) : AC(405)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Pomegranate juice increases sirtuin1 protein in peripheral blood mononuclear cell from patients with type 2 diabetes.

Pubmed Data : Metab Syndr Relat Disord. 2018 Jun 29. Epub 2018 Jun 29. PMID: 29957104
Article Published Date : Jun 28, 2018
Authors : Golbon Sohrab, Javad Nasrollahzadeh, Maryam Tohidi, Hamid Zand, Omid Nikpayam
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Diabetes Mellitus: Type 2 : CK(8552) : AC(1714)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), NF-kappaB Inhibitor : CK(3536) : AC(2098)

Pomegranate juice possesses a promising inhibitory effect on bladder cancer development.

Pubmed Data : Heliyon. 2020 Oct ;6(10):e05192. Epub 2020 Oct 8. PMID: 33083625
Article Published Date : Sep 30, 2020
Authors : Wael I Mortada, Amira Awadalla, Sherry M Khater, Nashwa M Barakat, Sherif M Husseiny, Ahmed A Shokeir
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Bladder Cancer : CK(632) : AC(247)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Chemopreventive : CK(5374) : AC(1717), Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor : CK(214) : AC(142), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells.

Pubmed Data : J Agric Food Chem. 2006 Feb 8;54(3):980-5. PMID: 16448212
Article Published Date : Feb 08, 2006
Authors : Lynn S Adams, Navindra P Seeram, Bharat B Aggarwal, Yasunari Takada, Daniel Sand, David Heber
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Colon Cancer : CK(1493) : AC(954)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Antineoplastic Agents : CK(78) : AC(35)

Pomegranate leaf extract attenuates lung inflammation in mice with acute lung injury.

Pubmed Data : J Immunol Res. 2018 ;2018:6879183. Epub 2018 Feb 20. PMID: 29675437
Article Published Date : Dec 31, 2017
Authors : Aruanã Joaquim Matheus Costa Rodrigues Pinheiro, Jaciara Sá Gonçalves, Ádylla Wilenna Alves Dourado, Eduardo Martins de Sousa, Natilene Mesquita Brito, Lanna Karinny Silva, Marisa Cristina Aranha Batista, Joicy Cortez de Sá, Cinara Regina Aragão Vieira Monteiro, Elizabeth Soares Fernandes, Valério Monteiro-Neto, Lee Ann Campbell, Patrícia Maria Wiziack Zago, Lidio Gonçalves Lima-Neto
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Lung Injury: Acute : CK(321) : AC(159)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Pomegranate peel extract has a protective effect on concanavalin A-induced autoimmune hepatitis.

Pubmed Data : Biomed Pharmacother. 2018 Feb 8 ;100:213-220. Epub 2018 Feb 8. PMID: 29428670
Article Published Date : Feb 07, 2018
Authors : Tingting Wang, Ruoting Men, Mingxing Hu, Xiaoli Fan, Xiaoxue Yang, Xiaojun Huang, Tinghong Ye, Li Yang
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Hepatitis: Autoimmune : CK(43) : AC(9)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hepatoprotective : CK(5098) : AC(2264), Interferon Gamma Reducer : CK(58) : AC(24), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Pomegranate peel extract protects against the development of diabetic cardiomyopathy.

Pubmed Data : Front Pharmacol. 2023 ;14:1166653. Epub 2023 Mar 28. PMID: 37056985
Article Published Date : Dec 31, 2022
Authors : Mariam Ali Abo-Saif, Amany E Ragab, Amera O Ibrahim, Othman F Abdelzaher, Ahmed B M Mehanyd, Maha Saber-Ayad, Ola A El-Feky
Study Type : Animal Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : Cardiomyopathy : CK(222) : AC(82)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cardioprotective : CK(5377) : AC(1675), Interleukin-1 beta downregulation : CK(3041) : AC(1567)

Pomegranate peel polyphenols inhibits inflammation in LPS-induced RAW264.7 macrophages.

Pubmed Data : Food Nutr Res. 2019 ;63. Epub 2019 Apr 23. PMID: 31073284
Article Published Date : Dec 31, 2018
Authors : Lin Du, Jianke Li, Xitong Zhang, Lifang Wang, Weimin Zhang, Mi Yang, Chen Hou
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Pomegranate peel polyphenols reduce chronic low-grade inflammatory responses in rats fed a high-fat diet.

Pubmed Data : Food Funct. 2019 Nov 13. Epub 2019 Nov 13. PMID: 31720661
Article Published Date : Nov 12, 2019
Authors : Ruiqi Zhao, Xingyu Long, Junqi Yang, Lin Du, Xitong Zhang, Jianke Li, Chen Hou
Study Type : Animal Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62), Pomegranate Polyphenols : CK(20) : AC(9), Punicalagin : CK(127) : AC(78), Urolithin A : CK(88) : AC(47)
Diseases : High Fat Diet : CK(1267) : AC(602), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Gastrointestinal Agents : CK(3145) : AC(843)

Pomegranate peel, flower and seed oil have anti-inflammatory properties. Pomegranate seed oil also improved insulin sensitivity.

Pubmed Data : Arch Physiol Biochem. 2016 Jan 28:1-40. Epub 2016 Jan 28. PMID: 26822470
Article Published Date : Jan 27, 2016
Authors : Arij Harzallah, Mohamed Hammami, Malgorzata A Kępczyńska, David C Hislop, Jonathan R S Arch, Michael A Cawthorne, Mohamed S Zaibi
Study Type : Animal Study
Additional Links
Substances : Pomegranate flower : CK(9) : AC(5), Pomegranate Peel : CK(117) : AC(62), Pomegranate Seed : CK(35) : AC(15)
Diseases : Inflammation : CK(9572) : AC(3089), Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Insulin Sensitizers : CK(1185) : AC(244)

Pomegranate polyphenol punicalagin improves learning memory deficits, redox homeostasis, and neuroinflammation.

Pubmed Data : Phytother Res. 2023 Apr 24. Epub 2023 Apr 24. PMID: 37092799
Article Published Date : Apr 23, 2023
Authors : Peng Chen, Fuchao Chen, Jiexin Lei, Benhong Zhou
Study Type : Animal Study
Additional Links
Substances : Pomegranate Polyphenols : CK(20) : AC(9)
Diseases : Aging: Brain : CK(720) : AC(189), Brain Inflammation : CK(1101) : AC(567), Memory Disorders : CK(1067) : AC(339)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Neuroprotective Agents : CK(10404) : AC(4396)

Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease.

Pubmed Data : J Nutr. 2013 May ;143(5):597-605. Epub 2013 Mar 6. PMID: 23468550
Article Published Date : Apr 30, 2013
Authors : Lalida Rojanathammanee, Kendra L Puig, Colin K Combs
Study Type : In Vitro Study, Transgenic Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Brain: Microglial Activation : CK(164) : AC(98)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)
Additional Keywords : Phytotherapy : CK(3062) : AC(812), Plant Extracts : CK(14140) : AC(5210)

Pomegranate supplementation accelerates recovery of muscle damage and soreness and inflammatory markers.

Pubmed Data : PLoS One. 2016 ;11(10):e0160305. Epub 2016 Aug 20. PMID: 27764091
Article Published Date : Dec 31, 2015
Authors : Achraf Ammar, Mouna Turki, Hamdi Chtourou, Omar Hammouda, Khaled Trabelsi, Choumous Kallel, Osama Abdelkarim, Anita Hoekelmann, Mohamed Bouaziz, Fatma Ayadi, Tarak Driss, Nizar Souissi
Study Type : Human Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Muscle Soreness: Exercise-Induced : CK(204) : AC(22)
Therapeutic Actions : Exercise : CK(4855) : AC(736)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Pomegranate, apple and prickly pear vinegars may prevent HFD-induced obesity and obesity-related cardiac complications.

Pubmed Data : Pharm Biol. 2016 Sep 5:1-10. Epub 2016 Sep 5. PMID: 27595296
Article Published Date : Sep 04, 2016
Authors : Abdenour Bounihi, Arezki Bitam, Asma Bouazza, Lyece Yargui, Elhadj Ahmed Koceir
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar : CK(52) : AC(20), Pomegranate : CK(1222) : AC(405), Prickly Pear Cactus : CK(43) : AC(18), Vinegar : CK(149) : AC(42)
Diseases : High Fat Diet : CK(1267) : AC(602), Obesity : CK(6879) : AC(1686)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Anti-Obesity Agents : CK(2925) : AC(774)

Pomegranates have potential as a novel approach in ameliorating the inflammation and pain associated with a range of skin conditions.

Pubmed Data : Eur J Pharm Biopharm. 2016 Nov 17. Epub 2016 Nov 17. PMID: 27867111
Article Published Date : Nov 16, 2016
Authors : David M J Houston, Joachim Bugert, Stephen P Denyer, Charles M Heard
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62), Punicalagin : CK(127) : AC(78)
Diseases : Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Cyclooxygenase 2 Inhibitors : CK(1589) : AC(926)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Punica granatum peel extract as adjunct irrigation to nonsurgical treatment of chronic gingivitis.

Pubmed Data : Complement Ther Clin Pract. 2021 May ;43:101383. Epub 2021 Apr 2. PMID: 33862350
Article Published Date : Apr 30, 2021
Authors : Eiba G Eltay, Bakri Gobara Gismalla, Maowia M Mukhtar, Mona O A Awadelkarim
Study Type : Human Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : Gingivitis : CK(541) : AC(77)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-1 beta downregulation : CK(3041) : AC(1567)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

Punicalagin in combination with zinc may promote certain anti-inflammatory and fibroblast responses to aid oral healing.

Pubmed Data : Biomolecules. 2020 Aug 25 ;10(9). Epub 2020 Aug 25. PMID: 32854243
Article Published Date : Aug 24, 2020
Authors : Vildan Celiksoy, Rachael L Moses, Alastair J Sloan, Ryan Moseley, Charles M Heard
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405), Punicalagin : CK(127) : AC(78), Zinc : CK(1486) : AC(267)
Diseases : Wound Healing : CK(1362) : AC(477)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Punicalin alleviates TNF-α- and IL-1β-induced chondrocyte dysfunction and cartilage metabolism via mediating FOXO3 signaling axis.

Pubmed Data : J Food Biochem. 2021 May 11:e13755. Epub 2021 May 11. PMID: 33974280
Article Published Date : May 10, 2021
Authors : Lin Yang, Changdong Fan, Taipengfei Shu, Shujun Wang
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Osteoarthritis : CK(1449) : AC(363)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Chondroprotective : CK(1) : AC(1), Osteoprotective : CK(971) : AC(351)

Punicalin ameliorates cell pyroptosis induced by LPS/ATP through suppression of ROS/NLRP3 pathway.

Pubmed Data : J Inflamm Res. 2021 ;14:711-718. Epub 2021 Mar 5. PMID: 33707964
Article Published Date : Dec 31, 2020
Authors : Ruiting Shen, Peng Yin, Hua Yao, Lu Chen, Xinyu Chang, Huanrong Li, Xiaolin Hou
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Punicic acid, a conjugated linolenic fatty acid from pomegranate seed oil, protects from experimental colon inflammation in rats by inhibiting TNF alpha-induced neutrophil hyperactiviation.

Pubmed Data : PLoS One. 2009 Jul 31;4(7):e6458. PMID: 19649246
Article Published Date : Jul 31, 2009
Authors : Tarek Boussetta, Houssam Raad, Philippe Lettéron, Marie-Anne Gougerot-Pocidalo, Jean-Claude Marie, Fathi Driss, Jamel El-Benna
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405), Punicic acid : CK(8) : AC(6)
Diseases : Inflammatory Bowel Diseases : CK(1994) : AC(540)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Punicic acid: A potential compound of pomegranate seed oil in type 2 diabetes mellitus management.

Pubmed Data : J Cell Physiol. 2018 Oct 14. Epub 2018 Oct 14. PMID: 30317607
Article Published Date : Oct 13, 2018
Authors : Yaser Khajebishak, Laleh Payahoo, Mohammadreza Alivand, Beitollah Alipour
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405), Punicic acid : CK(8) : AC(6)
Diseases : Diabetes Mellitus: Type 2 : CK(8552) : AC(1714)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hypoglycemic Agents : CK(5366) : AC(1338)

Supplementation with a punicalagin-rich pomegranate extract may protect skeletal muscle against an acute inflammation.

Pubmed Data : Mol Nutr Food Res. 2016 Nov 2. Epub 2016 Aug 2. PMID: 27804206
Article Published Date : Nov 01, 2016
Authors : Julie Rodriguez, Olivier Caille, Daneel Ferreira, Marc Francaux
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405), Punicalagin : CK(127) : AC(78), Urolithin A : CK(88) : AC(47)
Diseases : Cachexia : CK(83) : AC(29), Inflammation : CK(9572) : AC(3089)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

Tart cherry and pomegranate supplementations enhance recovery from exercise-induced muscle damage.

Pubmed Data : Biol Sport. 2021 Mar ;38(1):97-111. Epub 2020 Aug 8. PMID: 33795919
Article Published Date : Feb 28, 2021
Authors : Daniel Rojano Ortega, Antonio Molina López, Heliodoro Moya Amaya, Francisco José Berral de la Rosa
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405), Tart Cherry : CK(231) : AC(38)
Diseases : Muscle Damage: Exercise-Induced : CK(570) : AC(68)
Therapeutic Actions : Exercise : CK(4855) : AC(736)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

The antiarthritic potential of a butanol fraction of Punica granatum Linn. rind extract may be due to the presence of active phytoconstituents.

Pubmed Data : J Environ Pathol Toxicol Oncol. 2018 ;37(1):53-62. PMID: 29773000
Article Published Date : Dec 31, 2017
Authors : Rupesh Kumar Gautam, Sanjay Sharma, Komal Sharma, Gaurav Gupta
Study Type : Animal Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : Arthritis : CK(3858) : AC(899)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)
Additional Keywords : Phytotherapy : CK(3062) : AC(812), Plant Extracts : CK(14140) : AC(5210)

The effects of pomegranate supplementation on biomarkers of inflammation and endothelial dysfunction.

Pubmed Data : Complement Ther Med. 2020 Mar ;49:102358. Epub 2020 Feb 26. PMID: 32147056
Article Published Date : Feb 29, 2020
Authors : Peng Wang, Qiang Zhang, Huijuan Hou, Zhiyong Liu, Li Wang, Reyhaneh Rasekhmagham, Hamed Kord-Varkaneh, Heitor O Santos, Guangtao Yao
Study Type : Meta Analysis, Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Endothelial Dysfunction : CK(2115) : AC(440)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-6 Downregulation : CK(5029) : AC(1994), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

The present data highlights the chondroprotective effects of pomegranate fruit extract consumption.

Pubmed Data : Nutrition. 2017 Jan ;33:1-13. Epub 2016 Sep 2. PMID: 27908544
Article Published Date : Dec 31, 2016
Authors : Nahid Akhtar, Nazir M Khan, Omer S Ashruf, Tariq M Haqqi
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Osteoarthritis : CK(1449) : AC(363)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Chondroprotective : CK(1) : AC(1), Matrix Metalloproteinase-13 (MMP-13) Inhibitor : CK(145) : AC(66)

The use of pomegranate peel extracts could lead to early healing of skin wounds.

Pubmed Data : Adv Skin Wound Care. 2016 May ;29(5):217-25. PMID: 27089150
Article Published Date : Apr 30, 2016
Authors : Omidreza Zekavat, Aida Amanat, Mohammadyasin Karami, Shahram Paydar, Bita Gramizadeh, Maryam Zareian-Jahromi
Study Type : Animal Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : Wound Healing : CK(1362) : AC(477)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

The waste peel of pomegranate has anti-inflammatory activity in cells and tissues of the gastrointestinal tract.

Pubmed Data : Nutrients. 2019 Mar 5 ;11(3). Epub 2019 Mar 5. PMID: 30841512
Article Published Date : Mar 04, 2019
Authors : Fabio Mastrogiovanni, Anindya Mukhopadhya, Nicola Lacetera, Marion T Ryan, Annalisa Romani, Roberta Bernini, Torres Sweeney
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Pomegranate Peel : CK(117) : AC(62)
Diseases : Gastrointestinal Inflammation : CK(261) : AC(117)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

There exists strong evidence from animal models suggesting pomegranate juice can be used to effectively treat IBD, and chronic inflammatory diseases.

Pubmed Data : Nutrients. 2017 Aug 30 ;9(9). Epub 2017 Aug 30. PMID: 28867799
Article Published Date : Aug 29, 2017
Authors : Francesca Danesi, Lynnette R Ferguson
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Hyperlipidemia : CK(1569) : AC(402), Inflammation : CK(9572) : AC(3089), Inflammatory Bowel Diseases : CK(1994) : AC(540)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334)

These findings support the protective effects of pomegranate fruit extract against high-fat diet-induced hepatic and neurological disease.

Pubmed Data : Int J Food Sci Nutr. 2020 Nov 18:1-12. Epub 2020 Nov 18. PMID: 33203257
Article Published Date : Nov 17, 2020
Authors : Marisa Pfohl, Nicholas A DaSilva, Emily Marques, Juliana Agudelo, Chang Liu, Michael Goedken, Angela L Slitt, Navindra P Seeram, Hang Ma
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Nonalcoholic fatty liver disease (NAFLD) : CK(1862) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Hepatoprotective : CK(5098) : AC(2264), Neuroprotective Agents : CK(10404) : AC(4396)

These results indicate the potential use of pomegranate polyphenolics in the therapeutic treatment of ulcerative colitis.

Pubmed Data : J Nutr Biochem. 2017 Feb 27 ;43:107-115. Epub 2017 Feb 27. PMID: 28282584
Article Published Date : Feb 26, 2017
Authors : Hyemee Kim, Nivedita Banerjee, Maritza A Sirven, Yasushi Minamoto, Melissa E Markel, Jan S Suchodolski, Stephen T Talcott, Susanne U Mertens-Talcott
Study Type : Animal Study
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Colitis : CK(840) : AC(406)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Anti-Ulcer Agents : CK(523) : AC(184), Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor : CK(214) : AC(142), MicroRNA modulator : CK(1023) : AC(618)
Additional Keywords : Dose Response : CK(1712) : AC(683)

This review aims at providing an overview of the chemical constituents, antibacterial, anti-inflammatory, and antioxidant properties of P. granatum.

Pubmed Data : J Pharm Bioallied Sci. 2017 Nov ;9(Suppl 1):S11-S14. PMID: 29284927
Article Published Date : Oct 31, 2017
Authors : Arthiie Thangavelu, Sugumari Elavarasu, Rajasekar Sundaram, Tamilselvan Kumar, Dhivya Rajendran, Fairlin Prem
Study Type : Review
Additional Links
Substances : Pomegranate : CK(1222) : AC(405)
Diseases : Periodontitis : CK(378) : AC(98)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251), Anti-Inflammatory Agents : CK(20859) : AC(8334)

This document is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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