Chemothapeutic Synergy: Paclitaxel

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35 Diseases Researched for Chemothapeutic Synergy: Paclitaxel
NameACCKFocus
Breast Cancer2329Locked
Lung Cancer1014Locked
Breast Cancer: Triple Negative 810Locked
Cancers: All78Locked
Carcinoma: Non-Small-Cell Lung68Locked
Ovarian Cancer78Locked
Cancers: Drug Resistant57Locked
Cervical Cancer67Locked
Gastric Cancer45Locked
Prostate Cancer45Locked
Cancers: Multi-Drug Resistant34Locked
Glioma24Locked
Kidney Cancer33Locked
Non-Small-Cell Lung Carcinoma33Locked
Pancreatic Cancer33Locked
Bladder Cancer12Locked
Bone Cancer22Locked
Chemotherapy-Induced Toxicity: Paclitaxel12Locked
Chemotherapy-Induced Toxicity: Tamoxifen12Locked
Colon Cancer22Locked
Ehrlich carcinoma12Locked
Head and Neck Cancer12Locked
Liver Cancer22Locked
Thyroid Cancer12Locked
Acute Myeloid Leukemia11Locked
Breast Cancer Stem Cells11Locked
Cancer Metastasis11Locked
Choriocarcinoma11Locked
Colorectal Cancer11Locked
Endometrial Cancer11Locked
Esophageal Cancer11Locked
Glioblastoma11Locked
Intestinal Cancer11Locked
Oral Cancer11Locked
Skin Cancer11Locked
58 Substances Researched for Chemothapeutic Synergy: Paclitaxel
NameACCKFocus
Curcumin1113Locked
Ginsenosides46Locked
Nobiletin 35Locked
Beta-Elemene44Locked
Honokiol44Locked
Ligustrazine23Locked
Modified Arabinoxylan Rice Bran (MGN-3)23Locked
Silibinin23Locked
Thymoquinone33Locked
Vitamin D23Locked
Bamboo12Locked
Berbamine12Locked
Caffeic Acid12Locked
Cannabidiol12Locked
Cannabinoids 12Locked
Cannabinoids: Synthetic12Locked
Carvacrol12Locked
Echinacea12Locked
Flavonoids12Locked
Ginseng (Korean)12Locked
Lotus 12Locked
Mulberry12Locked
Paeonol12Locked
Piperlongumine 22Locked
Shikonin22Locked
Tomato12Locked
Vitamin C12Locked
Wogonin12Locked
Alpha-Lipoic Acid11Locked
Artesunate11Locked
Ashwagandha11Locked
Berberine11Locked
Betulinic acid11Locked
Bitter Melon11Locked
Citrus naringin11Locked
Crocin11Locked
Cucurbitacin B 11Locked
Diosmetin11Locked
Ellagic Acid11Locked
Fermented Foods and Beverages11Locked
Fisetin11Locked
Folic Acid 11Locked
Gallic Acid11Locked
Geraniol 11Locked
Gingerol 11Locked
Hydroxytyrosol11Locked
Luteolin11Locked
Modified Citrus Pectin 11Locked
Nettle11Locked
Panax Ginseng11Locked
Psychedelics:All 11Locked
Quercetin11Locked
Resveratrol11Locked
Spirulina11Locked
Sulforaphane11Locked
Tanshinone IIA11Locked
Ursolic Acid11Locked
Viruses: Beneficial11Locked
2 Therapeutic Actions Researched for Chemothapeutic Synergy: Paclitaxel
NameACCKFocus
Heat Therapy11Locked
Ultrasound therapy11Locked
33 Pharmacological Actions Researched for Chemothapeutic Synergy: Paclitaxel
NameACCKFocus
Apoptotic3649Locked
Chemosensitizer3747Locked
Antiproliferative 2330Locked
Chemotherapeutic2127Locked
Cell cycle arrest912Locked
NF-kappaB Inhibitor79Locked
Antineoplastic Agents68Locked
Bcl-2 protein down-regulation57Locked
Anti-metastatic56Locked
Chemopreventive23Locked
Tumor Suppressor Protein p53 Upregulation33Locked
Vascular Endothelial Growth Factor Inhibitors23Locked
Anti-Inflammatory Agents22Locked
Cannabinoid Receptor Antagonist/Inverse Agonist12Locked
Chemoprotective Agents12Locked
Cyclooxygenase 2 Inhibitors22Locked
Immunomodulatory22Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor22Locked
Multidrug Resistance Gene Modulators22Locked
P21 Activation22Locked
PI3K-AKT inhibitor12Locked
Radiosensitizer22Locked
Angiogenesis Inhibitors11Locked
Bax/Bcl2 ratio: Increase11Locked
Caspase-3 Activation11Locked
Heat Shock Protein Down-Regulation11Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor11Locked
MicroRNA modulator11Locked
Paraptosis11Locked
STAT3 Inhibitor11Locked
Survivin Down-Regulation11Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor11Locked

View the Evidence:
84 Abstracts with Chemothapeutic Synergy: Paclitaxel Research

[+]

A multiple-targets alkaloid nuciferine overcomes paclitaxel-induced drug resistance in vitro and in vivo.Sep 09, 2020

Pubmed Data : Phytomedicine. 2020 Sep 10 ;79:153342. Epub 2020 Sep 10. PMID: 32992085
Article Published Date : Sep 09, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lotus
Diseases : Cancers: Drug Resistant, Lung Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Bamboo concentrate enhances the bioavailability of the chemotherapy agent paclitaxel. Nov 01, 2010

Pubmed Data : Radiat Res. 2010 Nov;174(5):624-36. Epub 2010 Sep 13. PMID: 15918522
Article Published Date : Nov 01, 2010
Study Type : Animal Study
Additional Links
Substances : Bamboo
Diseases : Chemotherapy-Induced Toxicity: Tamoxifen
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Berbamine has synergistic antitumor effects with paclitaxel in glioma cells.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:8152526. Epub 2017 Aug 13. PMID: 28883885
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Berbamine
Diseases : Glioma
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Caffeic acid inhibited non-small-cell lung cancer cell growth by inducing apoptosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2018 ;48(4):1433-1442. Epub 2018 Jul 31. PMID: 30064123
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Caffeic Acid
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma.Jan 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 11 26 ;10(1):20622. Epub 2020 Nov 26. PMID: 33244087
Article Published Date : Jan 25, 2020
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Head and Neck Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Cisplatin
[+]

Combinations of nobiletin with paclitaxel and carboplatin significantly suppressed the growth of subcutaneous A549 tumors xenografts in nude mice.Mar 31, 2014

Pubmed Data : Planta Med. 2014 Apr ;80(6):452-7. Epub 2014 Mar 31. PMID: 24687742
Article Published Date : Mar 31, 2014
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Drug: Carboplatin, Natural Substance/Drug Synergy, Plant Extracts
[+]

Curcumin and vitamin D3 enhanced the tumor response to paclitaxel.Oct 15, 2019

Pubmed Data : Chem Biol Interact. 2019 Oct 16 ;315:108865. Epub 2019 Oct 16. PMID: 31628941
Article Published Date : Oct 15, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin, Vitamin D
Diseases : Breast Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Curcumin is a potent chemosensitizer to improve the therapeutic index of paclitaxel.Jul 13, 2011

Pubmed Data : Oncogene. 2011 Jul 14 ;30(28):3139-52. Epub 2011 Feb 14. PMID: 21317920
Article Published Date : Jul 13, 2011
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cervical Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer, NF-kappaB Inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Echinacea angustifolia extract is a potential candidate for breast cancer treatment.Sep 21, 2020

Pubmed Data : Nutr Cancer. 2020 Sep 22:1-19. Epub 2020 Sep 22. PMID: 32959676
Article Published Date : Sep 21, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Echinacea
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Exogenous vitamin C boosts the antitumor efficacy of paclitaxel containing reduction-sensitive shell-sheddable micelles in vivo.Feb 01, 2017

Pubmed Data : J Control Release. 2017 Feb 2. Epub 2017 Feb 2. PMID: 28163212
Article Published Date : Feb 01, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Breast Cancer, Glioma
Additional Keywords : Breast Cancer, Chemothapeutic Synergy: Paclitaxel, Glioma, Vitamin C
[+]

Flavopiridol and paclitaxel exerted synergistic cytotoxic activities against SKOV3 cells in vitro and significantly suppress the tumor growth of mice bearing SKOV3 cells.Dec 31, 2014

Pubmed Data : Arch Gynecol Obstet. 2015 Jan ;291(1):143-50. Epub 2014 Aug 14. PMID: 25118834
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Ovarian Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Ginsenoside Rg3 promotes cytotoxicity and apoptosis of Paclitaxel by inhibiting NF-κB signalling.Feb 19, 2017

Pubmed Data : Biomed Pharmacother. 2017 Feb 20 ;89:227-232. Epub 2017 Feb 20. PMID: 28231544
Article Published Date : Feb 19, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Bcl-2 protein down-regulation, Chemosensitizer, NF-kappaB Inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer.Nov 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):3465-3477. PMID: 31432702
Article Published Date : Nov 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ligustrazine
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Anti-metastatic, Chemotherapeutic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Korean red ginseng extract enhances paclitaxel distribution to mammary tumors.May 16, 2016

Pubmed Data : Xenobiotica. 2016 May 17:1-10. Epub 2016 May 17. PMID: 27189791
Article Published Date : May 16, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Bioavailability, Chemothapeutic Synergy: Paclitaxel, Plant Extracts
[+]

MGN-3 supplementation enhances tumor cell demise in the presence of a low dose of paclitaxel.Jun 30, 2016

Pubmed Data : Nutr Cancer. 2016 Jul 1:1-11. Epub 2016 Jul 1. PMID: 27367621
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Modified Arabinoxylan Rice Bran (MGN-3)
Diseases : Ehrlich carcinoma
Pharmacological Actions : Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Mulberry water extract enhanced the cytotoxicity of paclitaxel and induced severe G2/M arrest, mitotic catastrophe and subsequent apoptosis.Dec 31, 2015

Pubmed Data : Sci Rep. 2016 ;6:20417. Epub 2016 Feb 3. PMID: 26838546
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Mulberry
Diseases : Bladder Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemopreventive
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Plant Extracts
[+]

Nobiletin reversed paclitaxel resistance in multi-drug resistance tumors.Nov 25, 2019

Pubmed Data : Phytomedicine. 2019 Nov 26 ;67:153141. Epub 2019 Nov 26. PMID: 31884406
Article Published Date : Nov 25, 2019
Study Type : Animal Study
Additional Links
Substances : Nobiletin
Diseases : Cancers: Multi-Drug Resistant, Lung Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Paeonol reversed paclitaxel resistance in MCF-7/PTX cells by downregulating the activity of the SET/PP2A/Akt pathway.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2015 Jul ;12(1):1506-14. Epub 2015 Mar 11. PMID: 25760096
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Paeonol
Diseases : Breast Cancer, Cancers: Drug Resistant
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Protective effect of carvacrol against paclitaxel-induced ototoxicity. Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk Arch Otorhinolaryngol. 2020 Dec ;58(4):241-248. Epub 2020 Dec 1. PMID: 33554199
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Chemotherapy-Induced Toxicity: Paclitaxel
Pharmacological Actions : Chemoprotective Agents
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Silybin and paclitaxel in dextran-based nanoparticles are an effective treatment through chemotherapy sensitization and microenvironment modulation.Feb 06, 2020

Pubmed Data : J Control Release. 2020 Feb 7 ;321:198-210. Epub 2020 Feb 7. PMID: 32044390
Article Published Date : Feb 06, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Silibinin
Diseases : Cancers: All
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Tumor Microenvironment
[+]

The discovery of IL-12-induced CB2 overexpression in thyroid cancer cells may offer a new target for anaplastic thyroid cancer treatmentJan 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Gene Ther. 2008 Feb ;15(2):101-7. Epub 2007 Dec 21. PMID: 18197164
Article Published Date : Jan 31, 2008
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids , Cannabinoids: Synthetic
Diseases : Thyroid Cancer
Pharmacological Actions : Apoptotic, Cannabinoid Receptor Antagonist/Inverse Agonist, Chemosensitizer
Additional Keywords : Cannabinoid Receptors, Chemothapeutic Synergy: Paclitaxel
[+]

The synergistic anti cancer effects of paclitaxel and α-tomatine may be beneficial for refractory prostate cancer treatment.Nov 14, 2013

Pubmed Data : Phytomedicine. 2013 Nov 15 ;20(14):1297-305. Epub 2013 Aug 4. PMID: 23920276
Article Published Date : Nov 14, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tomato
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, PI3K-AKT inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Plant Extracts, Significant Treatment Outcome
[+]

These results showed that 20(s)-ginsenoside Rg3 enhanced the oral bioavailability of paclitaxel.Oct 31, 2012

Pubmed Data : Biopharm Drug Dispos. 2012 Nov ;33(8):425-36. Epub 2012 Sep 21. PMID: 22898996
Article Published Date : Oct 31, 2012
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Wogonin combined with low-dose paclitaxel obtained the same efficacy as with high dose Paclitaxel reducing tumor burden by 61%.Sep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin J Cancer Res. 2013 Oct ;25(5):505-13. PMID: 24255573
Article Published Date : Sep 30, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Natural Substance/Drug Synergy
[+]

Design and development of spirulina polysaccharide-loaded nanoemulsions with improved the antitumor effects of paclitaxel.May 25, 2020

Pubmed Data : J Microencapsul. 2020 May 26:1-10. Epub 2020 May 26. PMID: 32401077
Article Published Date : May 25, 2020
Study Type : In Vitro Study
Additional Links
Substances : Spirulina
Diseases : Cancers: All
Pharmacological Actions : Chemotherapeutic, Immunomodulatory
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Enhanced lysosomal function is critical for paclitaxel resistance in cancer cells: reversed by artesunate.Jul 22, 2020

Pubmed Data : Acta Pharmacol Sin. 2020 Jul 23. Epub 2020 Jul 23. PMID: 32704040
Article Published Date : Jul 22, 2020
Study Type : In Vitro Study
Additional Links
Substances : Artesunate
Diseases : Cancers: All
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Piperlongumine increases the apoptotic effect of doxorubicin and paclitaxel in a cervical cancer cell line.Feb 29, 2020

Pubmed Data : Niger J Clin Pract. 2020 Mar ;23(3):386-391. PMID: 32134040
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Cervical Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Doxorubicin
[+]

Piperlongumine induces ROS mediated cell death and synergizes paclitaxel in human intestinal cancer cells.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Aug ;128:110243. Epub 2020 May 27. PMID: 32470748
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Intestinal Cancer
Pharmacological Actions : Bcl-2 protein down-regulation, Chemosensitizer, P21 Activation, Survivin Down-Regulation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells.Apr 20, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2020 Apr 21 ;11(16):1399-1416. Epub 2020 Apr 21. PMID: 32362998
Article Published Date : Apr 20, 2020
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha
Diseases : Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Antiproliferative
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Synergistic killing effect of paclitaxel and honokiol in non-small cell lung cancer cells through paraptosis induction.Sep 15, 2020

Pubmed Data : Cell Oncol (Dordr). 2020 Sep 16. Epub 2020 Sep 16. PMID: 32936421
Article Published Date : Sep 15, 2020
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Chemosensitizer, Paraptosis
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

6-Gingerol with 5-flourouracil and paclitaxel resulted in 83.2% and 52% inhibition of cervical cancer cells. Feb 26, 2017

Pubmed Data : Food Chem Toxicol. 2017 Feb 27. Epub 2017 Feb 27. PMID: 28249781
Article Published Date : Feb 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Gingerol
Diseases : Cervical Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Bax/Bcl2 ratio: Increase, Cell cycle arrest
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemothapeutic Synergy: Paclitaxel
[+]

A combination of curcumin and paclitaxel exhibited synergistic anti-proliferative and pro-apoptosis effects on Hep3B cells.Jun 24, 2015

Pubmed Data : J Recept Signal Transduct Res. 2015 Jun 25:1-8. Epub 2015 Jun 25. PMID: 26108226
Article Published Date : Jun 24, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Kidney Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Apoptotic, Chemosensitizer, NF-kappaB Inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Beta-elemene had synergistic effect with paclitaxel.Jun 30, 2013

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Jul ;33(7):978-82. PMID: 24063225
Article Published Date : Jun 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Beta-Elemene
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Bitter melon extract treatment has a significant effect on uptake of the 99mTc-PAC on MCF-7 cells.Apr 23, 2020

Pubmed Data : Anticancer Agents Med Chem. 2020 Apr 24. Epub 2020 Apr 24. PMID: 32329694
Article Published Date : Apr 23, 2020
Study Type : In Vitro Study
Additional Links
Substances : Bitter Melon
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Chemovirotherapy of pancreatic adenocarcinoma by combining oncolytic vaccinia virus GLV-1h68 with nab-paclitaxel plus gemcitabine.Sep 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Ther Oncolytics. 2017 Sep 15 ;6:10-21. Epub 2017 Apr 19. PMID: 28607950
Article Published Date : Sep 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : Viruses: Beneficial
Diseases : Pancreatic Cancer
Pharmacological Actions : Immunomodulatory
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Gemcitabine, Chemovirotherapy
[+]

Co-delivery of paclitaxel and honokiol suppressed multidrug resistance and metastasis of breast cancer.Aug 27, 2017

Pubmed Data : Acta Biomater. 2017 Aug 28. Epub 2017 Aug 28. PMID: 28842335
Article Published Date : Aug 27, 2017
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Breast Cancer, Cancers: Multi-Drug Resistant
Pharmacological Actions : Anti-metastatic, Multidrug Resistance Gene Modulators
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Co-treatment with low dose berberine could significantly attenuate the anticancer activity of chemotherapeutic agents.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(9):e0139298. Epub 2015 Sep 30. PMID: 26421434
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Colon Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemothapeutic Synergy: Paclitaxel, Dose Response, Natural Substance/Drug Synergy
[+]

Combination of curcumin and paclitaxel liposomes exhibits enhanced cytotoxicity towards A549/A549-T cells.Jul 31, 2020

Pubmed Data : J Biomed Nanotechnol. 2020 Aug 1 ;16(8):1304-1313. PMID: 33397559
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Lung Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Combination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2019 ;14:7. Epub 2019 Mar 12. PMID: 30911326
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Ovarian Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Combined treatment of β-elemene-paclitaxel is more effective at inhibiting bone neoplasm growth than β-elemene or paclitaxel single treatment GPR124.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Aug ;16(2):2143-2150. Epub 2018 Jun 6. PMID: 30008912
Article Published Date : Jul 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Beta-Elemene
Diseases : Bone Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Combined ultrasonic treatment and chemotherapy with paclitaxel showed a significantly increased killing of MCF7 cells compared to both monotherapies.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015;10(8):e0134999. Epub 2015 Aug 4. PMID: 26241649
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Therapeutic Actions : Ultrasound therapy
Pharmacological Actions : Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Selective Cytotoxicity
[+]

Crocin and paclitaxel and crocin and gamma radiation had synergistic effect on MCF-7 cell line to get more significant apoptosis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Breast Cancer. 2015 ;2015:139349. Epub 2015 Nov 26. PMID: 26693354
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Crocin
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic, Radiosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Cucurbitacin B, showed potential in vitro synergistic antiproliferative effects combined with paclitaxel in A549 cells.Jun 09, 2017

Pubmed Data : Toxicol Appl Pharmacol. 2017 Jun 10 ;329:272-281. Epub 2017 Jun 10. PMID: 28610991
Article Published Date : Jun 09, 2017
Study Type : In Vitro Study
Additional Links
Substances : Cucurbitacin B
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative , Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Curcumin by itself was as good as carboplatin or paclitaxel in inducing apoptosis in the primary ovarian cancer cells.Mar 31, 2016

Pubmed Data : J Cancer Res Ther. 2016 Apr-Jun;12(2):1050-5. PMID: 27461697
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Ovarian Cancer
Pharmacological Actions : Apoptotic, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Carboplatin, Natural Substances Versus Drugs
[+]

Curcumin has the ability to improve the paclitaxel induced apoptosis of HPV positive human cervical cancer cell lines via the NF-κB-p53-caspase-3 pathway.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2015 Apr ;9(4):1470-1476. Epub 2015 Jan 29. PMID: 25780454
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic, Caspase-3 Activation, NF-kappaB Inhibitor, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Curcumin might be a potential adjuvant for non-small-cell lung cancer patients during Paclitaxel treatment.Mar 31, 2017

Pubmed Data : Tumour Biol. 2017 Apr ;39(4):1010428317698353. PMID: 28443468
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Chemosensitizer
Additional Keywords : Carcinoma: Non-Small-Cell Lung, Chemosensitizer, Chemothapeutic Synergy: Paclitaxel, CURCUMIN
[+]

Curcumin sensitized breast cancer cells to chemotherapeutic drugs by reducing the BCSC population mainly through a reduction in the expression of ABCG2.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(8):e0136694. Epub 2015 Aug 25. PMID: 26305906
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Breast Cancer Stem Cells
Pharmacological Actions : Apoptotic, Chemopreventive, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin, Chemotherapeutic Synergy: Mitomycin C
[+]

Cytotoxicity of Tanshinone IIA combined with Taxol on drug-resist breast cancer cells MCF-7 through inhibition of Tau.Mar 31, 2018

Pubmed Data : Phytother Res. 2018 Apr ;32(4):667-671. Epub 2018 Jan 24. PMID: 29368408
Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Breast Cancer, Cancers: Drug Resistant
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non-small cell lung cancer cells.May 31, 2019

Pubmed Data : Br J Pharmacol. 2019 Jun ;176(12):2079-2094. Epub 2019 May 11. PMID: 30825187
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Diosmetin
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Selective Cytotoxicity
[+]

Effect of Gallic acid in potentiating chemotherapeutic effect of paclitaxel in HeLa cervical cancer cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Cell Int. 2019 ;19:154. Epub 2019 Jun 3. PMID: 31171918
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Cervical Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Effect of ginseng rare ginsenoside components combined with paclitaxel on A549 lung cancer.Mar 31, 2018

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2018 Apr ;43(7):1446-1452. PMID: 29728035
Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Lung Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Fermented red ginseng extract may be more effective for decreasing cancer cell survival by inducing apoptotic cell death.Mar 31, 2015

Pubmed Data : J Med Food. 2015 Apr ;18(4):421-8. Epub 2015 Feb 6. PMID: 25658580
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Ginsenosides, Panax Ginseng
Diseases : Breast Cancer, Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Folic acid significantly enhanced the efficacy of curcumin in down-regulating various survival signals induced by paclitaxel in cervical cancer.Dec 07, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Dec 8 ;8(64):107374-107389. Epub 2017 Nov 10. PMID: 29296172
Article Published Date : Dec 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Folic Acid
Diseases : Cervical Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Functional paclitaxel plus honokiol micelles destroying tumour metastasis in treatment of non-small-cell lung cancer.Jul 24, 2018

Pubmed Data : Artif Cells Nanomed Biotechnol. 2018 Jul 25:1-16. Epub 2018 Jul 25. PMID: 30043652
Article Published Date : Jul 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Honokiol
Diseases : Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Geraniol can constrain the ability of tumor cells to acquire adaptive resistance against anticancer drugs.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2016 May ;48(5):1772-82. Epub 2016 Mar 9. PMID: 26983575
Article Published Date : Apr 30, 2016
Study Type : Review
Additional Links
Substances : Geraniol
Diseases : Breast Cancer, Cancers: All, Cancers: Drug Resistant, Colon Cancer, Kidney Cancer, Liver Cancer, Lung Cancer, Oral Cancer, Pancreatic Cancer, Prostate Cancer, Skin Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Antiproliferative , Apoptotic, Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin
[+]

Honokiol targets mitochondria to halt cancer progression and metastasis.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Nutr Food Res. 2016 Jun ;60(6):1383-95. Epub 2016 May 6. PMID: 27276215
Article Published Date : May 31, 2016
Study Type : Review
Additional Links
Substances : Honokiol
Diseases : Bone Cancer, Breast Cancer, Gastric Cancer, Glioblastoma, Kidney Cancer, Lung Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Chemosensitizer, Radiosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin, Chemotherapeutic Synergy: Gemcitabine, Chemotherapeutic Synergy: Oxaliplatin, Natural Substance/Drug Synergy
[+]

Liposomal co-delivery of curcumin and albumin/paclitaxel nanoparticle for enhanced synergistic antitumor efficacy.Mar 31, 2015

Pubmed Data : Colloids Surf B Biointerfaces. 2015 Apr 1 ;128:419-426. Epub 2015 Mar 7. PMID: 25797481
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, NF-kappaB Inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Liposomal codelivery of HSA-paclitaxel and HSA-ellagic acid complexes for enhanced drug perfusion and efficacy against pancreatic cancer.Aug 01, 2017

Pubmed Data : ACS Appl Mater Interfaces. 2017 Aug 2 ;9(30):25138-25151. Epub 2017 Jul 24. PMID: 28696100
Article Published Date : Aug 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid
Diseases : Pancreatic Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Luteolin plays an important role in the treatment of human choriocarcinoma cells.Aug 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Reprod. 2016 Aug 31. Epub 2016 Aug 31. PMID: 27580988
Article Published Date : Aug 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Luteolin
Diseases : Choriocarcinoma
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Cisplatin, Natural Substance/Drug Synergy
[+]

MGN-3 is an effective chemosensitizer and may represent a novel adjuvant for the treatment of metastatic breast cancer.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Res. 2014 Jan ;34(1):81-7. PMID: 24403447
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Modified Arabinoxylan Rice Bran (MGN-3)
Diseases : Breast Cancer, Cancer Metastasis
Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Modified citrus pectin targets galectin-3-induced STAT3 activation and synergize paclitaxel cytotoxic effect on ovarian cancer spheroids.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Med. 2019 Aug ;8(9):4315-4329. Epub 2019 Jun 13. PMID: 31197964
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Modified Citrus Pectin
Diseases : Ovarian Cancer
Pharmacological Actions : Chemotherapeutic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, STAT3 Inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Modulation by hydroxytyrosol of oxidative stress and antitumor activities of paclitaxel in breast cancer.Feb 20, 2018

Pubmed Data : Eur J Nutr. 2018 Feb 21. Epub 2018 Feb 21. PMID: 29468462
Article Published Date : Feb 20, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hydroxytyrosol
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Naringin acts as a chemosensitizer which synergistically strengthens the cytotoxic effect of paclitaxel in prostate cancer cells.Nov 30, 2018

Pubmed Data : Prostate Int. 2018 Dec ;6(4):126-135. Epub 2017 Nov 28. PMID: 30505814
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Prostate Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Nettle extract substantially increased sensitivity of breast cancer cells to paclitaxel.Aug 04, 2016

Pubmed Data : Biomed Pharmacother. 2016 Aug 5 ;83:835-842. Epub 2016 Aug 5. PMID: 27501501
Article Published Date : Aug 04, 2016
Study Type : In Vitro Study
Additional Links
Substances : Nettle
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Cell cycle arrest, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Plant Extracts
[+]

Nobiletin significantly reversed ABCB1 mediated multidrug resistance in cancer cells. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:18789. Epub 2015 Dec 22. PMID: 26689156
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Nobiletin
Diseases : Cancers: All, Cancers: Multi-Drug Resistant, Colorectal Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic, Multidrug Resistance Gene Modulators
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Doxorubicin
[+]

Paclitaxel and curcumin coadministration in novel cationic PEGylated niosomal formulations exhibit enhanced synergistic antitumor efficacy.Mar 22, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nanobiotechnology. 2018 Mar 23 ;16(1):28. Epub 2018 Mar 23. PMID: 29571289
Article Published Date : Mar 22, 2018
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Selective Cytotoxicity
[+]

Paclitaxel combined with harmine inhibits the migration and invasion of gastric cancer cells.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2015 Sep ;10(3):1649-1654. Epub 2015 Jun 25. PMID: 26622726
Article Published Date : Aug 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Psychedelics:All
Diseases : Gastric Cancer
Pharmacological Actions : Anti-metastatic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Paclitaxel-betulinic acid hybrid nanosuspensions for enhanced anti-breast cancer activity.Jan 31, 2019

Pubmed Data : Colloids Surf B Biointerfaces. 2019 Feb 1 ;174:270-279. Epub 2018 Nov 14. PMID: 30469048
Article Published Date : Jan 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Quercetin enhanced paclitaxel therapeutic effects towards PC-3 prostate cancer. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2020 ;13:513-523. Epub 2020 Jan 16. PMID: 32021294
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Quercetin
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Resveratrol enhances chemosensitivity of renal cell carcinoma to paclitaxel.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Biosci (Landmark Ed). 2019 Jun 1 ;24:1452-1461. Epub 2019 Jun 1. PMID: 31136990
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Shikonin can sensitize esophageal cancer cells to paclitaxel-treatment.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2019 Sep ;18(3):3195-3201. Epub 2019 Jul 25. PMID: 31452796
Article Published Date : Aug 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Shikonin
Diseases : Esophageal Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Chemosensitizer, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells.Feb 26, 2017

Pubmed Data : Cancer Lett. 2017 Feb 27. Epub 2017 Feb 27. PMID: 28254410
Article Published Date : Feb 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Cancer Stem Cells, Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Docetaxel
[+]

Synergistic apoptotic effects of silibinin in enhancing paclitaxel toxicity in human gastric cancer cell lines.Jul 31, 2018

Pubmed Data : Mol Med Rep. 2018 Aug ;18(2):1835-1841. Epub 2018 Jun 5. PMID: 29901126
Article Published Date : Jul 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Silibinin
Diseases : Gastric Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Tetramethylpyrazine enhances the antitumor effect of paclitaxel by inhibiting angiogenesis and inducing apoptosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:707. Epub 2019 Jun 25. PMID: 31293426
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Ligustrazine
Diseases : Ovarian Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

The combination of fisetin and paclitaxel is expected to have a synergistic anticancer efficacy and a significant potential for the treatment of NSCLC.Feb 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Feb 27 ;19(3). Epub 2018 Feb 27. PMID: 29495431
Article Published Date : Feb 26, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fisetin
Diseases : Non-Small-Cell Lung Carcinoma
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Thermotherapy in combination with chemotherapy showed more strong inhibitory effect than those of thermotherapy or chemotherapy alone.Aug 31, 2008

Pubmed Data : Wei Sheng Yan Jiu. 2008 Sep ;37(5):529-32. PMID: 19069644
Article Published Date : Aug 31, 2008
Study Type : In Vitro Study
Additional Links
Diseases : Lung Cancer
Therapeutic Actions : Heat Therapy
Pharmacological Actions : Heat Shock Protein Down-Regulation
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Therapeutic Action Synergy with Drugs
[+]

Thymoquinone and paclitaxel combined act in synergy against triple negative breast cancer cells.Oct 25, 2015

Pubmed Data : Tumour Biol. 2015 Oct 26. Epub 2015 Oct 26. PMID: 26500095
Article Published Date : Oct 25, 2015
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic, P21 Activation
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Gene Expression Regulation
[+]

Thymoquinone enhances paclitaxel anti-breast cancer activity.Jan 19, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Jan 20 ;25(2). Epub 2020 Jan 20. PMID: 31968657
Article Published Date : Jan 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Cancer Stem Cells, Chemothapeutic Synergy: Paclitaxel
[+]

Thymoquinone is a potentially effective suppressor of inflammation, tumor cell survival, proliferation, invasion, and angiogenesis.May 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Cancer Res. 2008 Jun ;6(6):1059-70. PMID: 18567808
Article Published Date : May 31, 2008
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Acute Myeloid Leukemia, Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Doxorubicin
[+]

Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Med Biol Res. 2020 ;53(6):e8885. Epub 2020 May 8. PMID: 32401925
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Beta-Elemene
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Ursolic acid reverses the chemoresistance of breast cancer cells to paclitaxel.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2019 ;9:501. Epub 2019 Jun 14. PMID: 31259152
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Ursolic Acid
Diseases : Breast Cancer, Cancers: Drug Resistant
Pharmacological Actions : Chemosensitizer, MicroRNA modulator
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Vitamin D may further contribute to the cytotoxic effect of paclitaxel and carboplatin.Jan 11, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anticancer Res. 2017 12 ;37(12):6575-6581. PMID: 29187432
Article Published Date : Jan 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Endometrial Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Carboplatin
[+]

α-Lipoic acid sensitizes lung cancer cells to chemotherapeutic agents.Jul 17, 2016

Pubmed Data : Int J Oncol. 2016 Jul 18. Epub 2016 Jul 18. PMID: 27431988
Article Published Date : Jul 17, 2016
Study Type : In Vitro Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Lung Cancer
Pharmacological Actions : Anti-metastatic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Cisplatin
[+]

β-elemene and taxanes synergistically induce cytotoxicity and inhibit proliferation in ovarian cancer and other tumor cells.Feb 28, 2013

Pubmed Data : Anticancer Res. 2013 Mar ;33(3):929-40. PMID: 23482764
Article Published Date : Feb 28, 2013
Study Type : In Vitro Study
Additional Links
Substances : Beta-Elemene
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Docetaxel

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