Drug: Zidovudine

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3 Diseases Researched for Drug: Zidovudine

Name	AC	CK
HIV Infections	1	10
Endothelial Dysfunction	1	1
HIV Drug-Induced Toxicity	1	1

4 Substances Researched for Drug: Zidovudine

Name	AC	CK
Ginseng (American)	1	10
Ginsenosides	1	10
Glutathione	1	1
NAC (N-acetyl-L-cysteine)	1	1

4 Pharmacological Actions Researched for Drug: Zidovudine

Name	AC	CK
Antioxidants	2	11
Anti-HIV Agents	1	10
HIV Protease Inhibitors	1	10
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	1

Research Articles 2
Cumulative Knowledge Score 3
Overall Research Rating GOOD

View the Evidence:
2 Abstracts with Drug: Zidovudine Research

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American ginseng reduces oxidative stress in patients taking the antiviral medication zidovudine without altering drug pharmacokinetics. May 01, 2008

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Pubmed Data : J Clin Pharmacol. 2008 May;48(5):599-609. Epub 2008 Mar 4. PMID: 18319359

Article Published Date : May 01, 2008

Study Type : Human Study

Additional Links

Substances : Ginseng (American), Ginsenosides

Diseases : HIV Infections

Pharmacological Actions : Anti-HIV Agents, Antioxidants, HIV Protease Inhibitors

Additional Keywords : Drug: Zidovudine, Plant Extracts

[+]

The antioxidants NAC and glutathione attenuate oxidative stress and endothelial dysfunction caused by active antiretroviral therapy. Jan 01, 2004

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Pubmed Data : Cardiovasc Toxicol. 2004;4(3):287-302. PMID: 15470276

Article Published Date : Jan 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Glutathione, NAC (N-acetyl-L-cysteine)

Diseases : Endothelial Dysfunction, HIV Drug-Induced Toxicity

Pharmacological Actions : Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Drug: Efavirenz, Drug: Indinavir, Drug: Nelfinavir, Drug: Zidovudine, Drug Side Effect Attenuation

Research Articles 2
Cumulative Knowledge Score 3
Overall Research Rating GOOD

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View the Evidence: 2 Abstracts with Drug: Zidovudine Research

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American ginseng reduces oxidative stress in patients taking the antiviral medication zidovudine without altering drug pharmacokinetics. May 01, 2008

Click here to read the entire abstract

The antioxidants NAC and glutathione attenuate oxidative stress and endothelial dysfunction caused by active antiretroviral therapy. Jan 01, 2004

Click here to read the entire abstract

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Drug: Zidovudine

View the Evidence:
2 Abstracts with Drug: Zidovudine Research