Epigenetic Modification

Name	AC	CK
Bisphenol A	7	18
Aromatic hydrocarbons	1	10
Infant Formula	1	10
Soy	1	10
Endocrine Disruptors	3	3
Chlorpyrifos	1	2
Electronic Cigarettes	1	2
Etoposide	1	2
Vinclozolin	1	2
Aluminum	1	1
Mercury	1	1
Pesticides	1	1
Pitocin (Synthetic Oxytocin)	1	1

Name	AC	CK
Prenatal Chemical Exposures	5	36
Fetal Origin of Adult Disease	4	24
Smoking	2	22
Asthma	1	20
Cancers: All	19	20
Breast Cancer	7	16
Bisphenol Toxicity	3	14
Aging	3	12
Cesarean Section	2	11
Oral Cancer	2	11
Celiac Disease: Prevalance	1	10
Celiac Disease: Prevention	1	10
Diabetes Mellitus: Type 2: Prevention	1	10
Female Reproductive Development Abnormalities	1	10
Inflammation	8	10
Polycystic Ovary Syndrome	1	10
Sleep Disorders	1	10
Cardiovascular Diseases	4	6
DNA damage	4	6
Cervical Cancer	1	5
Neurodegenerative Diseases	5	5
Oxidative Stress	4	5
Prostate Cancer	5	5
Alzheimer's Disease	3	4
Colon Cancer	3	4
Folic Acid/Folate Deficiency	2	4
Autoimmune Diseases	2	3
Diabetes: Cardiovascular Illness	2	3
Alcohol Toxicity	2	2
Breast Cancer: Chemically-Induced	1	2
Cardiomyopathy	1	2
Cardiomyopathy: Hypertrophic	1	2
Colitis	1	2
Cystic Fibrosis	1	2
Diabetes Mellitus: Type 1	1	2
Diabetes Mellitus: Type 2	2	2
Diabetes: Kidney Function	1	2
Diabetic Nephropathy	1	2
Dry Mouth	1	2
Endocrine Imbalances	2	2
Epilepsy	1	2
Fatty Liver	1	2
Graves Disease	1	2
Gulf War Syndrome	1	2
Hyperlipidemia	1	2
Hypertension	1	2
Hyperthyroidism	1	2
Infertility: Male	1	2
Inflammatory Bowel Diseases	1	2
Kidney Diseases	1	2
Leukemia	1	2
Melanoma: Metastatic	2	2
Memory Disorders	1	2
Morphine Tolerance/Dependence	1	2
Pesticide Toxicity	1	2
Post-Traumatic Stress Disorders (PTSD)	1	2
Prenatal Nutrition: Health of the Offspring	1	2
Salivary Gland Diseases	1	2
Sexual Development: Dysfunctions and Abnormalities	1	2
Stroke: Ischemic	1	2
Vitamin B 12 Deficiency	1	2
Vitamin B Deficiency	1	2
Zinc Deficiency	1	2
Abnormalities	1	1
Aging: Brain	1	1
Aluminum Toxicity	1	1
Amyotrophic Lateral Sclerosis	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Bipolar Disorder	1	1
Birth: Labor & Delivery	1	1
Bladder Cancer	1	1
Bone Diseases	1	1
Bone Fractures	1	1
Brain Inflammation	1	1
Brain: Microglial Activation	1	1
Breast Cancer: BRCA1	1	1
Breast Cancer: Metastatic	1	1
Breast Cancer: Triple Negative	1	1
Cancers: Drug Resistant	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Cardiovascular Disease: Prevention	1	1
Circadian Dysregulation	1	1
Colon Cancer: Prevention	1	1
Colorectal Cancer	1	1
Depression	1	1
Diabetes Mellitus: Type 1: Prevention	1	1
Drug-Induced	1	1
Epstein-Barr Virus Infections	1	1
Gastric Cancer	1	1
Glioma	1	1
HIV Infections	1	1
Infertility	1	1
Infertility: Female	1	1
Insulin Resistance	1	1
Lipid Peroxidation	1	1
Lung Cancer	1	1
Melanoma	1	1
Metabolic Diseases	1	1
Neuroblastoma	1	1
Neutropenia: Severe Congenital	1	1
Osteoporosis	1	1
Oxytocin: Low Levels	1	1
Pancreatic Cancer	1	1
Parkinson's Disease	1	1
Psychiatric Disorders	1	1
Schizophrenia	1	1
Skin Cancer	1	1
Stress	1	1
Stroke	1	1
Stroke: Attenuation/Recovery	1	1
Testicular Cancer	1	1
Vitamin D Deficiency	1	1

Name	AC	CK
Cesarean Delivery	3	21
Prenatal Stress	2	3
Artifical Lighting	2	2
Mobile Phone Radiation	1	2

Name	AC	CK	Focus
Immunotoxic	1	10
Endocrine Disruptor	1	2

Name	AC	CK
Polyphenols	10	21
Curcumin	12	16
Black Raspberry	2	15
Flavonoids	3	13
Vitamin C	12	12
Breast Milk	1	10
Vitamin B-12	1	10
Sulforaphane	7	8
EGCG (Epigallocatechin gallate)	6	6
Resveratrol	4	6
Amla Fruit	1	5
Folic Acid	3	4
Genistein	4	4
Isoflavones	3	4
Apples	2	3
Melatonin	3	3
Catechin	2	2
Delta-tetrahydrocannabinol (THC)	1	2
Folate	1	2
Ginseng (American)	1	2
Indole-3-Carbinol	2	2
Saccharomyces Boulardii	1	2
Soy	1	2
Tetrahydrocurcumin	1	2
Wogonin	1	2
Anthocyanins	1	1
Black Tea	1	1
Blueberry	1	1
Broccoli	1	1
Chaparral	1	1
Cruciferous Vegetables	1	1
Epicatechin	1	1
Garlic	1	1
Glutathione	1	1
Green Tea	1	1
Isothiocyanates	1	1
Luteolin	1	1
Phospholipids	1	1
Polyunsaturated Fatty Acids (PUFAs)	1	1
Quercetin	1	1
S-Adenosylmethionine (SAMe)	1	1
Silibinin	1	1
Spirulina	1	1
Stilbenes	1	1
Thyme	1	1
Vitamin A	1	1
Vitamin B12: methylcobalamin	1	1
Vitamin B6	1	1
Vitamin D	1	1

Name	AC	CK
Breastfeeding	1	10
Electroacupuncture	1	10
Exercise	1	10
Exercise: Endurance	1	10
Meditation	1	10
Dietary Modification: Low Carbohydrate/Ketogenic	2	3
Dietary Modification: Mediterranean Diet	1	2
Acupuncture	1	1
Dietary Modification: Low Calorie Diet	1	1
Reiki Therapy	1	1

Name	AC	CK
MicroRNA modulator	9	28
Chemopreventive	11	25
Antiproliferative	6	14
Apoptotic	9	14
Histone deacetylase inhibitor	12	12
Anticarcinogenic Agents	6	11
Antioxidants	8	11
Gene Protective	2	11
Anti Inflammatory	1	10
Antineoplastic Agents	4	8
Anti-metastatic	3	7
Neuroprotective Agents	5	7
Antiviral Agents	2	6
Anti-Angiogenic	1	5
Anti-Tumor	1	5
Tumor Necrosis Factor (TNF) Alpha Inhibitor	3	5
Vascular Endothelial Growth Factor Inhibitors	1	5
anti-inflammatory	1	5
Anti-Inflammatory Agents	4	4
Hepatoprotective	2	4
Immunomodulatory	3	4
NF-kappaB Inhibitor	3	4
Telomerase Inhibitor	3	3
Anticonvulsants	1	2
Cell cycle arrest	2	2
DNA Repair Up-regulation	1	2
Hypolipidemic	1	2
Hypotensive	1	2
Interleukin-6 Downregulation	1	2
Nrf2 activation	2	2
Tumor Suppressor Protein p53 Upregulation	2	2
Vasodilator Agents	1	2
Angiogenesis Inhibitors	1	1
Antimutagenic Agents	1	1
Cardioprotective	1	1
Caspase-9 Activation	1	1
Chemotherapeutic	1	1
Enzyme Inhibitors	1	1
Estrogen Receptor Modulators	1	1
Glutathione Upregulation	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1
Regenerative	1	1

[+]

Click here to read the entire abstract

Pubmed Data : Acta Paediatr. 2009 Jul ;98(7):1096-9. PMID: 19638013

Article Published Date : Jun 30, 2009

Study Type : Human Study

Additional Links

Diseases : Cesarean Section

Additional Keywords : DNA Methylation, Epigenetic Modification

Anti Therapeutic Actions : Cesarean Delivery

[+]

Girls fed soy formula had altered DNA methylation in vaginal cell DNA which may be associated with decreased expression of an estrogen-responsive gene.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

"Epigenetic instability in ES cells and cloned mice."Jul 05, 2001

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neuropharmacology. 2015 Aug 6 ;99:500-509. Epub 2015 Aug 6. PMID: 26256422

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Open. 2015 Jun 19. Epub 2015 Jun 19. PMID: 26092868

Article Published Date : Jun 18, 2015

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Cystic Fibrosis, Dry Mouth, Salivary Gland Diseases

Additional Keywords : Epigenetic Modification

[+]

S. boulardii reduces colonic inflammation in a rat experimental model of Colitis.Jul 10, 2008

Click here to read the entire abstract

Pubmed Data : Dig Dis Sci. 2008 Jul 10. PMID: 18612822

Click here to read the entire abstract

Pubmed Data : Neurochem Int. 2019 Jan ;122:120-138. Epub 2018 Nov 22. PMID: 30472160

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Tetrahydrocurcumin

Diseases : Stroke: Ischemic

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Epigenetic Modification

[+]

The fungicide Vinclozolin has been shown to have lasting transgenerational endocrine disrupting effects on male reproduction.Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Semin Reprod Med. 2009 Sep;27(5):403-8. Epub 2009 Aug 26. PMID: 19711250

Click here to read the entire abstract

Pubmed Data : Epigenetics. 2018 Jul 12. Epub 2018 Jul 12. PMID: 30001178

Article Published Date : Jul 11, 2018

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity

Additional Keywords : Epigenetic Modification

Problem Substances : Bisphenol A

[+]

Thymoquinone may enhance the developmental competence of polycystic ovary syndrome oocytes.Jun 16, 2019

Click here to read the entire abstract

Pubmed Data : Mol Reprod Dev. 2019 Jun 17. Epub 2019 Jun 17. PMID: 31209968

Article Published Date : Jun 16, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Polycystic Ovary Syndrome

Pharmacological Actions : Antioxidants

Additional Keywords : Epigenetic Modification

[+]

Wogonin can be a promising chemoprotective agent and might be useful to avert secondary leukemia and other drug related cancers.Aug 31, 2013

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2013 Sep ;59:724-30. Epub 2013 Jul 17. PMID: 23872129

Article Published Date : Aug 31, 2013

Study Type : Animal Study

Click here to read the entire abstract

Pubmed Data : Int J Oncol. 2012 Jul ;41(1):353-61. Epub 2012 Apr 26. PMID: 22552582

Article Published Date : Jun 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Catechin , Polyphenols

Diseases : Prostate Cancer

Pharmacological Actions : Apoptotic, Histone deacetylase inhibitor, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Epigenetic Modification, Plant Extracts

[+]

"Humanity and human DNA."Sep 30, 2012

Blueberry anthocyanins inhibited proliferation and induced apoptosis in oral cancer cells in a dose dependent manner. Jun 19, 2014

Click here to read the entire abstract

Pubmed Data : Yi Chuan. 2014 Jun 20 ;36(6):566-73. PMID: 24929515

Article Published Date : Jun 19, 2014

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Blueberry

Diseases : Oral Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Caspase-9 Activation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Epigenetic Modification, Methylation Downregulation

[+]

Both epidemiological and experimental evidences demonstrate that BPA affects reproduction-related gene expression and epigenetic modification that are closely associated with infertility.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : AAPS J. 2011 Dec ;13(4):606-14. Epub 2011 Sep 22. PMID: 21938566

Article Published Date : Dec 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Prostate Cancer

Additional Keywords : Epigenetic Modification

[+]

Curcumin supplementation by reducing vascular inflammation may prevent diabetic complications.Jul 21, 2010

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2010 Jul 21. Epub 2010 Jul 21. PMID: 20655188

Click here to read the entire abstract

Pubmed Data : Cancer. 2009 Nov 2. PMID: 19885928

Article Published Date : Nov 02, 2009

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Prostate Cancer

Additional Keywords : Epigenetic Modification

[+]

Highl doses of ascorbate up regulated 32 miRNAs 4-fold, mainly involved in tumor suppression and drug resistance.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Altern Med. 2016 Jul 12 ;16:208. Epub 2016 Jul 12. PMID: 27405852

Article Published Date : Jul 11, 2016

Study Type : In Vitro Study

Additional Links

Substances : Peony

Diseases : Brain: Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents

Additional Keywords : Epigenetic Modification, Plant Extracts

[+]

Overexpression of miR-7-1 can highly potentiate efficacy of EGCG for induction of apoptosis in human malignant neuroblastoma cells.Jan 31, 2013

Click here to read the entire abstract

Pubmed Data : Neurochem Res. 2013 Feb ;38(2):420-32. Epub 2012 Nov 30. PMID: 23192662

Click here to read the entire abstract

Pubmed Data : J Nutr. 2010 Sep;140(9):1607-14. Epub 2010 Jul 14. PMID: 20631324

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2014 Jul 22 ;11(7):7537-61. Epub 2014 Jul 22. PMID: 25054232

Article Published Date : Jul 21, 2014

Study Type : Review

Additional Links

Diseases : Cancers: All, Infertility

Additional Keywords : Epigenetic Modification

Problem Substances : Bisphenol A

[+]

The anti-inflammatory effects of Spirulina platensis extracts act via the modulation of histone deacetylases.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2016 ;8(6). Epub 2016 Jun 21. PMID: 27338466

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Curr Pharmacol Rep. 2015 Nov 1 ;1(6):382-390. Epub 2015 Apr 16. PMID: 26557472

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr Cancer. 2013 ;65 Suppl 1:3-11. PMID: 23682778

Click here to read the entire abstract

Pubmed Data : Biol Chem. 2016 Jun 25. Epub 2016 Jun 25. PMID: 27343473

Article Published Date : Jun 24, 2016

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Additional Keywords : Epigenetic Modification, Gene Expression Regulation

[+]

Vitamin C supplied protection against the cell cycle arrest induced by aromatic alkylanilines.Apr 30, 2015

Click here to read the entire abstract

Pubmed Data : J Appl Toxicol. 2015 May ;35(5):466-77. Epub 2014 Sep 1. PMID: 25178734

Article Published Date : Apr 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Bladder Cancer, DNA damage, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants, Histone deacetylase inhibitor

Additional Keywords : Epigenetic Modification

[+]

Vitamin C treatment increases 5hmC content in melanoma cells, while causing a decrease in tumor-cell invasiveness and clonogenic growth in soft agar.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Epigenetics. 2015 ;7(1):51. Epub 2015 Apr 29. PMID: 25977731

Article Published Date : Dec 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Melanoma: Metastatic, Skin Cancer

Pharmacological Actions : Anti-metastatic

Additional Keywords : Epigenetic Modification

[+]

When Vitamin D is deficient, many processes begin to decline and this sets the stage for the onset of diseases such as diabetes.Mar 23, 2017

Click here to read the entire abstract

Pubmed Data : Biochem J. 2017 Mar 24 ;474(8):1321-1332. Epub 2017 Mar 24. PMID: 28341729

Article Published Date : Mar 23, 2017

Study Type : Review

Additional Links

Substances : Vitamin D

Diseases : Diabetes Mellitus: Type 1: Prevention, Diabetes Mellitus: Type 2, Insulin Resistance, Oxidative Stress, Vitamin D Deficiency

Additional Keywords : Epigenetic Modification

Epigenetic Modification jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 129 Abstracts with Epigenetic Modification Research

Limited to Members Only

Currently Available Sorting Options

This study found substantial persistence of the effects of maternal smoking identified in newborns into later childhood.Apr 06, 2016

A single bout of electroacupuncture remodels epigenetic and transcriptional changes in adipose tissue in polycystic ovary syndrome.Jan 29, 2018

B12 supplementation influences regulation of several metabolically important Type 2 diabetes-associated genes through methylation of miR21.Nov 13, 2017

Breast-feeding protects against celiac disease. May 01, 2002

Celiac disease prevalence is higher in females, but suprisingly more common in HLA-DQ2/8 negative males, suggesting a sex bias and possible parent-specific epigenetic modifications in the two genders.Apr 01, 2008

Childhood exposure to ambient polycyclic aromatic hydrocarbons is linked to epigenetic modifications and impaired systemic immunity in T cells.Dec 31, 2014

Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF ) after acute psychosocial stress.Dec 31, 2011

Endurance training positively affects thousands of DNA methylation sites and genes which leads to improvement in muscle function and health.Dec 01, 2014

Epigenetic modulation at birth - altered DNA-methylation in white blood cells after Caesarean section.Jun 30, 2009

Girls fed soy formula had altered DNA methylation in vaginal cell DNA which may be associated with decreased expression of an estrogen-responsive gene.Dec 31, 2016

Physical exercise improves breast cancer survival and is likely mediated through epigenetic modification of breast tunmors.Aug 12, 2011

Prenatal bisphenol A exposure is linked to epigenetic changes in glutamate receptor subunit gene grin2b in female rats and humans.Jul 26, 2018

Short-term sleep deprivation leads to decreased systemic redox metabolites and altered epigenetic status.Dec 31, 2016

Synesthesia in twins: incomplete concordance in monozygotes suggests extragenic factors.May 31, 2015

The mode of delivery could affect the epigenetic state of newborn infants.Oct 31, 2014

This hypothesizes that the cumulative effects of a regular meditation practice may help to slow the epigenetic clock.Oct 31, 2017

This pilot study provides the first evidence of miRNA modulation by diet and other factors, that can be detected consistently in both plasma and stools samples.Aug 31, 2014

A Black Raspberry extract could prevent the initiation, promotion, and progression of carcinogenesis in the digestive tract and esophagus.Oct 27, 2014

An extract of Amla fruit inhibited human papillomavirus viral oncogenes responsible for development and progression of cervical cancer.Dec 31, 2012

"Epigenetic instability in ES cells and cloned mice."Jul 05, 2001

A high methionine, low folate and vitamin B6/B12 containing diet can be associated with memory loss.Jun 30, 2019

American Ginseng positively effects the phenotype expression of genes associated with diabetes in the male rat.Oct 17, 2007

Apples may exert their colon cancer protective effects through favorably altering gene patterns resulting in protection of cells against toxicological insults. Jun 15, 2008

Chlorpyrifos may act as a breast cancer risk factor.Oct 01, 2018

Curcumin blocks chronic morphine analgesic tolerance and positively modulates brain chemistry. Jan 07, 2009

Curcumin may play a role in preventing diabetes-induced cardiomyopathy. Jun 01, 2008

Curcumin protects against the development of diabetic nephropathy, in a diabetic rat experimental model. Mar 01, 2008

Delta-tetrahydrocannabinol (THC) may modulate immune response through epigenetic regulation involving histone modifications.Jul 03, 2014

Exposure to radiofrequency radiation emitted by GSM mobile phones can lead to epigenetic detrimental changes in ERα promoter methylation pattern.Feb 28, 2017

fetal BPA exposure triggers changes in the postnatal and adult mammary gland epigenome and alters gene expression patterns.Dec 31, 2013

Folic acid increases methylation potential and DNMT activity, modifies DNA methylation and ultimately decreases APP, PS1 and Aβ protein levels.Jul 31, 2015

Ketogenic diet therapy might be uniquely suited to reset the epileptogenic clock and to provide long-lasting relief from seizures even after discontinuation of the diet.Aug 05, 2015

Maternal E-cigarette exposure results in cognitive and epigenetic alterations in offspring in a mouse model.Jun 03, 2018

Plant-derived polyphenols prevent fatty liver disease through by regulating the expressions of miRNA .Jun 30, 2012

Post-traumatic stress may be associated with methylation of DNA via epigenetic modifications.Apr 01, 2010

Prenatal stress alters gene and protein expression in the hippocampus and the prefrontal cortex of PS offspring.Dec 31, 2013

Results from this study implicate a role for epigenetic alterations in Gulf War Illness.Jun 30, 2016

Resveratrol attenuates cigarette smoke-induced oxidative stress and proinflammatory alterations. Jun 01, 2008

Resveratrol partially rescues the refractory CFTR dependent β adrenergic response of saliva secretion in female CF mice.Jun 18, 2015

S. boulardii reduces colonic inflammation in a rat experimental model of Colitis.Jul 10, 2008

Soma-to-Germline Transmission of RNA in Mice Xenografted with Human Tumour Cells: Possible Transport by Exosomes.Dec 31, 2013

Soy isoflavones in the fetal circulation may play during fetal development in affording protection against cardiovascular disease in the offspring.Feb 05, 2011

Sulforaphane normalizes the kidney epigenome and improves blood pressure in hypertensive rats.Nov 03, 2011

Tetrahydrocurcumin epigenetically mitigates mitochondrial dysfunction in brain vasculature during ischemic stroke.Dec 31, 2018

The fungicide Vinclozolin has been shown to have lasting transgenerational endocrine disrupting effects on male reproduction.Sep 01, 2009

The Mediterranean diet positively influences key genes involved in vascular inflammation, foam cell formation and thrombosis.Aug 08, 2009

The protective effect of curcumin to PTU-induced hepatotoxicity is attributed to its antioxidative properties.Oct 23, 2018

These findings suggest BPA exposure induced non- ethinyl estradiol-like gene expression and epigenetic changes in hippocampus of adult rats.Jul 11, 2018

Thymoquinone may enhance the developmental competence of polycystic ovary syndrome oocytes.Jun 16, 2019

Wogonin can be a promising chemoprotective agent and might be useful to avert secondary leukemia and other drug related cancers.Aug 31, 2013

Zinc deficiency induced inflammatory response in part by eliciting aberrant immune cell activation and altered promoter methylation. Feb 04, 2015

"Epigenetic: a molecular link between testicular cancer and environmental exposures."Dec 31, 2011

"Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class I histone deacetylases."Jun 30, 2012

"Humanity and human DNA."Sep 30, 2012

A garlic extract, Diallyl disulfide, modulates gene expression in colon cells, inhibiting tumorigenesis. Jul 01, 2004

A number of studies now indicate that the epigenome is responsive to external environmental exposures, including the social environment.May 31, 2015

A review evaluating the modulation of miRNAs by dietary agents, which could potentially be exploited for inhibition of mutagenesis and carcinogenesis.Sep 30, 2012

A review of the epigenetic role of vitamin C in health and disease.Mar 31, 2016

A review of the molecular mechanisms of pharmacological doses of ascorbate on cancer cells.May 31, 2015

Alcohol-induced epigenetic changes in cancer.Dec 31, 2017

Apple may exert its protective effect against colorectal cancer through acting as a histone-deacetylase inhibitor. Apr 01, 2008

Artificial light at night: melatonin as a mediator between the environment and epigenome.May 04, 2015

Artificial light at night: melatonin as a mediator between the environment and epigenome.May 04, 2015

Ascorbate is a critical mediator of the interface between our genomes and our environment.May 09, 2013

Blueberry anthocyanins inhibited proliferation and induced apoptosis in oral cancer cells in a dose dependent manner. Jun 19, 2014

Both epidemiological and experimental evidences demonstrate that BPA affects reproduction-related gene expression and epigenetic modification that are closely associated with infertility.Dec 31, 2014

Cross talk between aluminum and genetic susceptibility and epigenetic modification in Alzheimer's disease.Dec 31, 2017

Curcumin had an inhibitory effect on anchorage independent growth of HT29 cells at least in part by the epigenetic demethylation and up-regulation of DLEC1.Mar 14, 2015

Curcumin may have positive epigenetic effects in high prostate cancer. Dec 01, 2011

Curcumin supplementation by reducing vascular inflammation may prevent diabetic complications.Jul 21, 2010

DIM and isoflavone may lead to the reversal of a gemcitabine-resistant pancreatic cancer phenotype. Aug 15, 2009

EGCG changes the phenotype of invasive breast cancer cells, repressing malignancy. Jun 15, 2007

Epigenetic Modification

View the Evidence:
129 Abstracts with Epigenetic Modification Research