Eriodictyol

Name	AC	CK	Focus
Multiple Myeloma	1	2

Name	AC	CK	Focus
EGCG (Epigallocatechin gallate)	1	2
Eriodictyol	1	2

Name	AC	CK	Focus
Antiproliferative	1	2
Apoptotic	1	2

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Eriodictyol alleviates lipopolysaccharide-triggered oxidative stress and synaptic dysfunctions.Aug 31, 2019

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Pubmed Data : J Cell Biochem. 2019 Sep ;120(9):14756-14770. Epub 2019 Apr 23. PMID: 31016762

Article Published Date : Aug 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Brain: Oxidative Stress, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation

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Eriodictyol attenuates arsenic trioxide-induced liver injury by activation of Nrf2.Sep 14, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Sep 15 ;8(40):68668-68674. Epub 2017 Aug 2. PMID: 28978146

Article Published Date : Sep 14, 2017

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Arsenic Poisoning, Chemically-Induced Liver Damage

Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation

Problem Substances : Arsenic Trioxide

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Eriodictyol attenuates cisplatin-induced kidney injury by inhibiting oxidative stress and inflammation.Feb 04, 2016

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2016 Feb 5 ;772:124-30. Epub 2015 Dec 23. PMID: 26723515

Article Published Date : Feb 04, 2016

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, NF-kappaB Inhibitor

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Eriodictyol attenuates lipopolysaccharide-induced acute lung injury through its antioxidative and anti-inflammatory activity.Nov 30, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2015 Dec ;10(6):2259-2266. Epub 2015 Oct 23. PMID: 26668626

Article Published Date : Nov 30, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation

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Eriodictyol attenuates LPS-induced neuroinflammation, amyloidogenesis, and cognitive impairments.Oct 02, 2018

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2018 Oct 3 ;66(39):10205-10214. Epub 2018 Sep 21. PMID: 30208700

Article Published Date : Oct 02, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Alzheimer's Disease, Brain Inflammation , Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor

[+]

Eriodictyol can be used as an effective chemopreventive agent against DMH-induced colon carcinogenesis.Aug 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Toxicol Res (Camb). 2017 Sep 1 ;6(5):678-692. Epub 2017 Jun 19. PMID: 30090535

Article Published Date : Aug 31, 2017

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

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Eriodictyol can protect against diet-induced obesity and related metabolic disturbances, including dyslipidemia, inflammation, fatty liver disease.Mar 10, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2019 Mar 11 ;20(5). Epub 2019 Mar 11. PMID: 30862092

Article Published Date : Mar 10, 2019

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Dyslipidemias, Fatty Liver, Inflammation, Insulin Resistance, Obesity

Pharmacological Actions : Anti-Inflammatory Agents, Glucagon Like Peptide 1 (GLP-1) Down-Regulation, Hepatoprotective, Hypolipidemic

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Eriodictyol exhibited an immunomodulatory effect that could be ascribed in part to a cytoprotective effect related to its anti-oxidant activity.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Stress Chaperones. 2016 09 ;21(5):773-81. Epub 2016 Jun 1. PMID: 27250501

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Immunomodulatory

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Eriodictyol may be a potential therapeutic resource for atopic dermatitis.Dec 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Pharm Bull. 2013 ;36(8):1375-9. PMID: 23902981

Article Published Date : Dec 31, 2012

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Atopic Dermatitis

Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents

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Eriodictyol may be used to treat acetaminophen-induced hepatotoxicity.Jan 04, 2017

Click here to read the entire abstract

Pubmed Data : Mol Pharm. 2017 09 5 ;14(9):2937-2951. Epub 2017 Jul 17. PMID: 28654297

Article Published Date : Jan 04, 2017

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced

Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation

Problem Substances : Acetaminophen, Paracetamol

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Eriodictyol might be a promising novel therapeutic agent for Alzheimer's disease.Jun 30, 2015

Click here to read the entire abstract

Pubmed Data : Neurochem Res. 2015 Jul ;40(7):1463-71. Epub 2015 May 21. PMID: 25994859

Article Published Date : Jun 30, 2015

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Alzheimer's Disease, Neurodegenerative Diseases

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation

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Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats.Jun 30, 2012

Click here to read the entire abstract

Pubmed Data : Biochem Pharmacol. 2012 Jul 1 ;84(1):88-92. Epub 2012 Mar 30. PMID: 22484312

Article Published Date : Jun 30, 2012

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Diabetic Retinopathy

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Eriodictyol stimulates insulin secretion.Feb 04, 2018

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2018 Feb 5 ;820:245-255. Epub 2017 Dec 8. PMID: 29229531

Article Published Date : Feb 04, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing

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Eriodictyol synergistically potentiates the anti-tumour effect of EGCG by amplifying 67LR-dependent signalling in MM cellsDec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2015 ;5:9474. Epub 2015 Mar 31. PMID: 25824377

Article Published Date : Dec 31, 2014

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Eriodictyol, Yerba Santa

Diseases : Multiple Myeloma

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Bioenhancer, EGCG Sensitizer, Natural Substance Synergy

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Eriodicyol inhibits osteoclast differentiation and ovariectomy-induced bone loss in vivo.Dec 09, 2015

Click here to read the entire abstract

Pubmed Data : Exp Cell Res. 2015 Dec 10 ;339(2):380-8. Epub 2015 Oct 9. PMID: 26450448

Article Published Date : Dec 09, 2015

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Osteoarthritis

Pharmacological Actions : Osteoprotective

Additional Keywords : Ovariectomy-Induced Changes

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These findings demonstrate that eriodictyol exhibit promising neuroprotection effects against the permanent focal ischemia cerebral injury.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Behav Brain Res. 2016 10 1 ;312:321-32. Epub 2016 Jun 25. PMID: 27353856

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Brain Inflammation , Brain Ischemia, Stroke

Pharmacological Actions : Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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These results demonstrated that eriodictyol could protect against myocardial ischemia-reperfusion injury.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2018 ;9:33. Epub 2018 Jan 30. PMID: 29441020

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Myocardial Ischemia

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cardioprotective, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

These results provided evidence for further investigation on myocardial protection and the treatment of myocardial infarction using eriodictyol.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2019 Jan ;17(1):551-557. Epub 2018 Nov 2. PMID: 30651835

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Eriodictyol

Diseases : Myocardial Infarction

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

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These results suggest that a combination of green tea and eriodictyol decreases cholesterol levels.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2016 ;62(4):249-256. PMID: 27725410

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Eriodictyol, Green Tea

Diseases : High Fat Diet, High Sugar Diet

Pharmacological Actions : Anticholesteremic Agents

Additional Keywords : Anti-Obesity Agents, Plant Extracts

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Anti-inflammatory effects of eriodictyol in lipopolysaccharide-stimulated raw 264.7 murine macrophages.Mar 31, 2011

Click here to read the entire abstract

Pubmed Data : Arch Pharm Res. 2011 Apr ;34(4):671-9. Epub 2011 May 5. PMID: 21544733

Article Published Date : Mar 31, 2011

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Cytoprotective effect of eriodictyol in UV-irradiated keratinocytes.Dec 31, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell Physiol Biochem. 2011 ;27(5):513-24. Epub 2011 Jun 15. PMID: 21691069

Article Published Date : Dec 31, 2010

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Cardioprotective, Photoprotective

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Eriodictyol and naringenin can inhibit the formation of advanced glycation end products.Oct 20, 2019

Click here to read the entire abstract

Pubmed Data : J Mol Recognit. 2019 Oct 21:e2814. Epub 2019 Oct 21. PMID: 31637788

Article Published Date : Oct 20, 2019

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol, Naringenin

Diseases : Advanced Glycation End products (AGE)

Pharmacological Actions : Anti-Glycation Agents

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Eriodictyol can increase glucose uptake and improve insulin resistance.Aug 07, 2012

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2012 Aug 8 ;60(31):7652-8. Epub 2012 Jul 31. PMID: 22809065

Article Published Date : Aug 07, 2012

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Diabetes Mellitus: Type 2, Insulin Resistance

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypoglycemic Agents

[+]

Eriodictyol induces long-term protection in ARPE-19 cells through its effects on Nrf2 activation and phase 2 gene expression.Apr 30, 2009

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Invest Ophthalmol Vis Sci. 2009 May ;50(5):2398-406. Epub 2008 Dec 30. PMID: 19117929

Article Published Date : Apr 30, 2009

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation

Additional Keywords : Gene Expression Regulation

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Eriodictyol inhibits high glucose-induced oxidative stress and inflammation in retinal ganglial cells.Mar 31, 2019

Click here to read the entire abstract

Pubmed Data : J Cell Biochem. 2019 Apr ;120(4):5644-5651. Epub 2018 Oct 14. PMID: 30317656

Article Published Date : Mar 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Diabetic Retinopathy

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-8 downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Eriodictyol inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes.Oct 31, 2018

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:1128-1134. Epub 2018 Aug 27. PMID: 30257325

Article Published Date : Oct 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Nrf2 activation

[+]

Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation.Jan 20, 2011

Click here to read the entire abstract

Pubmed Data : J Biol Chem. 2011 Jan 21 ;286(3):2057-66. Epub 2010 Nov 22. PMID: 21098035

Article Published Date : Jan 20, 2011

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Preneoplastic Conditions

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Chemopreventive

[+]

Eriodictyol might be a potential therapeutic agent for the treatment of rheumatoid arthritis.Aug 31, 2019

Click here to read the entire abstract

Pubmed Data : J Cell Biochem. 2019 Sep ;120(9):14628-14635. Epub 2019 Apr 22. PMID: 31009103

Article Published Date : Aug 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation

[+]

Eriodictyol protected mesangial cells from high glucose stimulation though inhibition of Akt/NF-κB pathway.Aug 01, 2019

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31373419

Article Published Date : Aug 01, 2019

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Diabetic Nephropathy

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Eriodictyol protects against H(2)O(2)-induced neuron-like PC12 cell death through activation of Nrf2/ARE signaling pathway.Jun 30, 2012

Click here to read the entire abstract

Pubmed Data : Neurochem Int. 2012 Jul ;61(2):251-7. Epub 2012 May 17. PMID: 22609376

Article Published Date : Jun 30, 2012

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Brain: Oxidative Stress, Hydrogen Peroxide Induced Toxicity

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation

[+]

Eriodictyol protects endothelial cells against oxidative stress-induced cell death.Jun 25, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2015 Jun 26 ;16(7):14526-39. Epub 2015 Jun 26. PMID: 26132561

Article Published Date : Jun 25, 2015

Study Type : In Vitro Study

Additional Links

Substances : Eriodictyol

Diseases : Cardiovascular Diseases, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective, Heme oxygenase-1 up-regulation

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View the Evidence: 31 Abstracts with Eriodictyol Research

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Eriodictyol alleviates lipopolysaccharide-triggered oxidative stress and synaptic dysfunctions.Aug 31, 2019

Eriodictyol attenuates arsenic trioxide-induced liver injury by activation of Nrf2.Sep 14, 2017

Eriodictyol attenuates cisplatin-induced kidney injury by inhibiting oxidative stress and inflammation.Feb 04, 2016

Eriodictyol attenuates lipopolysaccharide-induced acute lung injury through its antioxidative and anti-inflammatory activity.Nov 30, 2015

Eriodictyol attenuates LPS-induced neuroinflammation, amyloidogenesis, and cognitive impairments.Oct 02, 2018

Eriodictyol can be used as an effective chemopreventive agent against DMH-induced colon carcinogenesis.Aug 31, 2017

Eriodictyol can protect against diet-induced obesity and related metabolic disturbances, including dyslipidemia, inflammation, fatty liver disease.Mar 10, 2019

Eriodictyol exhibited an immunomodulatory effect that could be ascribed in part to a cytoprotective effect related to its anti-oxidant activity.Dec 31, 2015

Eriodictyol may be a potential therapeutic resource for atopic dermatitis.Dec 31, 2012

Eriodictyol may be used to treat acetaminophen-induced hepatotoxicity.Jan 04, 2017

Eriodictyol might be a promising novel therapeutic agent for Alzheimer's disease.Jun 30, 2015

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats.Jun 30, 2012

Eriodictyol stimulates insulin secretion.Feb 04, 2018

Eriodictyol synergistically potentiates the anti-tumour effect of EGCG by amplifying 67LR-dependent signalling in MM cellsDec 31, 2014

Eriodicyol inhibits osteoclast differentiation and ovariectomy-induced bone loss in vivo.Dec 09, 2015

These findings demonstrate that eriodictyol exhibit promising neuroprotection effects against the permanent focal ischemia cerebral injury.Dec 31, 2015

These results demonstrated that eriodictyol could protect against myocardial ischemia-reperfusion injury.Dec 31, 2017

These results provided evidence for further investigation on myocardial protection and the treatment of myocardial infarction using eriodictyol.Dec 31, 2018

These results suggest that a combination of green tea and eriodictyol decreases cholesterol levels.Dec 31, 2015

Anti-inflammatory effects of eriodictyol in lipopolysaccharide-stimulated raw 264.7 murine macrophages.Mar 31, 2011

Cytoprotective effect of eriodictyol in UV-irradiated keratinocytes.Dec 31, 2010

Eriodictyol and naringenin can inhibit the formation of advanced glycation end products.Oct 20, 2019

Eriodictyol can increase glucose uptake and improve insulin resistance.Aug 07, 2012

Eriodictyol induces long-term protection in ARPE-19 cells through its effects on Nrf2 activation and phase 2 gene expression.Apr 30, 2009

Eriodictyol inhibits high glucose-induced oxidative stress and inflammation in retinal ganglial cells.Mar 31, 2019

Eriodictyol inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes.Oct 31, 2018

Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation.Jan 20, 2011

Eriodictyol might be a potential therapeutic agent for the treatment of rheumatoid arthritis.Aug 31, 2019

Eriodictyol protected mesangial cells from high glucose stimulation though inhibition of Akt/NF-κB pathway.Aug 01, 2019

Eriodictyol protects against H(2)O(2)-induced neuron-like PC12 cell death through activation of Nrf2/ARE signaling pathway.Jun 30, 2012

Eriodictyol protects endothelial cells against oxidative stress-induced cell death.Jun 25, 2015

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Eriodictyol

View the Evidence:
31 Abstracts with Eriodictyol Research