Eriodictyol

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1 Diseases Researched for Eriodictyol
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Multiple Myeloma12Locked
2 Substances Researched for Eriodictyol
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EGCG (Epigallocatechin gallate)12Locked
Eriodictyol12Locked
2 Pharmacological Actions Researched for Eriodictyol
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Antiproliferative 12Locked
Apoptotic12Locked
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View the Evidence:
30 Abstracts with Eriodictyol Research

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Eriodictyol alleviates lipopolysaccharide-triggered oxidative stress and synaptic dysfunctions.Aug 31, 2019

Pubmed Data : J Cell Biochem. 2019 Sep ;120(9):14756-14770. Epub 2019 Apr 23. PMID: 31016762
Article Published Date : Aug 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Brain: Oxidative Stress, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation
[+]

Eriodictyol attenuates arsenic trioxide-induced liver injury by activation of Nrf2.Sep 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Sep 15 ;8(40):68668-68674. Epub 2017 Aug 2. PMID: 28978146
Article Published Date : Sep 14, 2017
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Arsenic Poisoning, Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective, Nrf2 activation
Problem Substances : Arsenic Trioxide
[+]

Eriodictyol attenuates cisplatin-induced kidney injury by inhibiting oxidative stress and inflammation.Feb 04, 2016

Pubmed Data : Eur J Pharmacol. 2016 Feb 5 ;772:124-30. Epub 2015 Dec 23. PMID: 26723515
Article Published Date : Feb 04, 2016
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, NF-kappaB Inhibitor
[+]

Eriodictyol attenuates lipopolysaccharide-induced acute lung injury through its antioxidative and anti-inflammatory activity.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2015 Dec ;10(6):2259-2266. Epub 2015 Oct 23. PMID: 26668626
Article Published Date : Nov 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation
[+]

Eriodictyol attenuates LPS-induced neuroinflammation, amyloidogenesis, and cognitive impairments.Oct 02, 2018

Pubmed Data : J Agric Food Chem. 2018 Oct 3 ;66(39):10205-10214. Epub 2018 Sep 21. PMID: 30208700
Article Published Date : Oct 02, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Alzheimer's Disease, Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Eriodictyol can be used as an effective chemopreventive agent against DMH-induced colon carcinogenesis.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Res (Camb). 2017 Sep 1 ;6(5):678-692. Epub 2017 Jun 19. PMID: 30090535
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Eriodictyol can protect against diet-induced obesity and related metabolic disturbances, including dyslipidemia, inflammation, fatty liver disease.Mar 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Mar 11 ;20(5). Epub 2019 Mar 11. PMID: 30862092
Article Published Date : Mar 10, 2019
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Dyslipidemias, Fatty Liver, Inflammation, Insulin Resistance, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Glucagon Like Peptide 1 (GLP-1) Down-Regulation, Hepatoprotective, Hypolipidemic
[+]

Eriodictyol exhibited an immunomodulatory effect that could be ascribed in part to a cytoprotective effect related to its anti-oxidant activity.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Stress Chaperones. 2016 09 ;21(5):773-81. Epub 2016 Jun 1. PMID: 27250501
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Immunomodulatory
[+]

Eriodictyol may be a potential therapeutic resource for atopic dermatitis.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2013 ;36(8):1375-9. PMID: 23902981
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents
[+]

Eriodictyol may be used to treat acetaminophen-induced hepatotoxicity.Jan 04, 2017

Pubmed Data : Mol Pharm. 2017 09 5 ;14(9):2937-2951. Epub 2017 Jul 17. PMID: 28654297
Article Published Date : Jan 04, 2017
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced
Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation
Problem Substances : Acetaminophen, Paracetamol
[+]

Eriodictyol might be a promising novel therapeutic agent for Alzheimer's disease.Jun 30, 2015

Pubmed Data : Neurochem Res. 2015 Jul ;40(7):1463-71. Epub 2015 May 21. PMID: 25994859
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Alzheimer's Disease, Neurodegenerative Diseases
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats.Jun 30, 2012

Pubmed Data : Biochem Pharmacol. 2012 Jul 1 ;84(1):88-92. Epub 2012 Mar 30. PMID: 22484312
Article Published Date : Jun 30, 2012
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Diabetic Retinopathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Eriodictyol stimulates insulin secretion.Feb 04, 2018

Pubmed Data : Eur J Pharmacol. 2018 Feb 5 ;820:245-255. Epub 2017 Dec 8. PMID: 29229531
Article Published Date : Feb 04, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
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Eriodictyol synergistically potentiates the anti-tumour effect of EGCG by amplifying 67LR-dependent signalling in MM cellsDec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:9474. Epub 2015 Mar 31. PMID: 25824377
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Eriodictyol, Yerba Santa
Diseases : Multiple Myeloma
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Bioenhancer, EGCG Sensitizer, Natural Substance Synergy
[+]

Eriodicyol inhibits osteoclast differentiation and ovariectomy-induced bone loss in vivo.Dec 09, 2015

Pubmed Data : Exp Cell Res. 2015 Dec 10 ;339(2):380-8. Epub 2015 Oct 9. PMID: 26450448
Article Published Date : Dec 09, 2015
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
Additional Keywords : Ovariectomy-Induced Changes
[+]

These findings demonstrate that eriodictyol exhibit promising neuroprotection effects against the permanent focal ischemia cerebral injury.Dec 31, 2015

Pubmed Data : Behav Brain Res. 2016 10 1 ;312:321-32. Epub 2016 Jun 25. PMID: 27353856
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Brain Inflammation , Brain Ischemia, Stroke
Pharmacological Actions : Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These results demonstrated that eriodictyol could protect against myocardial ischemia-reperfusion injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:33. Epub 2018 Jan 30. PMID: 29441020
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Myocardial Ischemia
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cardioprotective, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

These results provided evidence for further investigation on myocardial protection and the treatment of myocardial infarction using eriodictyol.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Jan ;17(1):551-557. Epub 2018 Nov 2. PMID: 30651835
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Eriodictyol
Diseases : Myocardial Infarction
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
[+]

These results suggest that a combination of green tea and eriodictyol decreases cholesterol levels.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2016 ;62(4):249-256. PMID: 27725410
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Eriodictyol, Green Tea
Diseases : High Fat Diet, High Sugar Diet
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Anti-Obesity Agents, Plant Extracts
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Anti-inflammatory effects of eriodictyol in lipopolysaccharide-stimulated raw 264.7 murine macrophages.Mar 31, 2011

Pubmed Data : Arch Pharm Res. 2011 Apr ;34(4):671-9. Epub 2011 May 5. PMID: 21544733
Article Published Date : Mar 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cytoprotective effect of eriodictyol in UV-irradiated keratinocytes.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2011 ;27(5):513-24. Epub 2011 Jun 15. PMID: 21691069
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Cardioprotective, Photoprotective
[+]

Eriodictyol can increase glucose uptake and improve insulin resistance.Aug 07, 2012

Pubmed Data : J Agric Food Chem. 2012 Aug 8 ;60(31):7652-8. Epub 2012 Jul 31. PMID: 22809065
Article Published Date : Aug 07, 2012
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypoglycemic Agents
[+]

Eriodictyol induces long-term protection in ARPE-19 cells through its effects on Nrf2 activation and phase 2 gene expression.Apr 30, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Invest Ophthalmol Vis Sci. 2009 May ;50(5):2398-406. Epub 2008 Dec 30. PMID: 19117929
Article Published Date : Apr 30, 2009
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
Additional Keywords : Gene Expression Regulation
[+]

Eriodictyol inhibits high glucose-induced oxidative stress and inflammation in retinal ganglial cells.Mar 31, 2019

Pubmed Data : J Cell Biochem. 2019 Apr ;120(4):5644-5651. Epub 2018 Oct 14. PMID: 30317656
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Diabetic Retinopathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-8 downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Eriodictyol inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes.Oct 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:1128-1134. Epub 2018 Aug 27. PMID: 30257325
Article Published Date : Oct 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Nrf2 activation
[+]

Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation.Jan 20, 2011

Pubmed Data : J Biol Chem. 2011 Jan 21 ;286(3):2057-66. Epub 2010 Nov 22. PMID: 21098035
Article Published Date : Jan 20, 2011
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Preneoplastic Conditions
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Chemopreventive
[+]

Eriodictyol might be a potential therapeutic agent for the treatment of rheumatoid arthritis.Aug 31, 2019

Pubmed Data : J Cell Biochem. 2019 Sep ;120(9):14628-14635. Epub 2019 Apr 22. PMID: 31009103
Article Published Date : Aug 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Eriodictyol protected mesangial cells from high glucose stimulation though inhibition of Akt/NF-κB pathway.Aug 01, 2019

Pubmed Data : Phytother Res. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31373419
Article Published Date : Aug 01, 2019
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Eriodictyol protects against H(2)O(2)-induced neuron-like PC12 cell death through activation of Nrf2/ARE signaling pathway.Jun 30, 2012

Pubmed Data : Neurochem Int. 2012 Jul ;61(2):251-7. Epub 2012 May 17. PMID: 22609376
Article Published Date : Jun 30, 2012
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Brain: Oxidative Stress, Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Eriodictyol protects endothelial cells against oxidative stress-induced cell death.Jun 25, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2015 Jun 26 ;16(7):14526-39. Epub 2015 Jun 26. PMID: 26132561
Article Published Date : Jun 25, 2015
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Cardiovascular Diseases, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective, Heme oxygenase-1 up-regulation

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