Paraquat

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3 Problem Substances Researched for Paraquat
NameACCKFocus
Paraquat510Locked
Cesium-13712Locked
Herbicide11Locked
9 Diseases Researched for Paraquat
NameACCKFocus
Parkinson's Disease13Locked
Fibrosis12Locked
Learning disorders12Locked
Neonatal Diseases and Abnormalities12Locked
Oxidative Stress12Locked
Parkinsonism12Locked
Pesticide Toxicity 12Locked
Radiation-Induced Illness: Cesium-137 Exposure12Locked
Herbicide Toxicity11Locked
1 Adverse Pharmacological Actions Researched for Paraquat
NameACCKFocus
Neurotoxic25Locked
2 Substances Researched for Paraquat
NameACCKFocus
Barberry12Locked
Chokeberry11Locked
5 Pharmacological Actions Researched for Paraquat
NameACCKFocus
Anti-Inflammatory Agents12Locked
Interleukin-6 Downregulation12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Antioxidants11Locked
Neuroprotective Agents11Locked

View the Evidence:
25 Abstracts with Paraquat Research

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Parkinson's disease due to laboral exposition to paraquatOct 31, 2012

Pubmed Data : Rev Med Inst Mex Seguro Soc. 2012 Nov-Dec;50(6):665-72. PMID: 23331754
Article Published Date : Oct 31, 2012
Study Type : Human: Case Report
Additional Links
Diseases : Parkinson's Disease
Problem Substances : Paraquat
Adverse Pharmacological Actions : Neurotoxic
[+]

Activated charcoal administrated at 30 minutes after paraquat poisoning can slow down the increased concentration in the plasma.Feb 28, 2017

Pubmed Data : Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2017 Mar ;29(3):211-215. PMID: 28627339
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Activated Charcoal
Diseases : Chemical Poisoning, Pesticide Toxicity
Pharmacological Actions : Detoxifier
Problem Substances : Paraquat
[+]

Apigenin reverses lung injury and immunotoxicity in paraquat-treated mice.Nov 30, 2018

Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:531-538. Epub 2018 Nov 6. PMID: 30408630
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Lung Injury: Acute, Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Paraquat
[+]

Astragaloside IV protective effect of against paraquat-induced lung injury.Jan 31, 2016

Pubmed Data : Inflammation. 2016 Feb ;39(1):483-492. PMID: 26452991
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Paraquat
[+]

Bacopa monnieri alleviates paraquat induced toxicity in Drosophila.Nov 30, 2018

Pubmed Data : Neurochem Int. 2018 Dec ;121:98-107. Epub 2018 Oct 5. PMID: 30296463
Article Published Date : Nov 30, 2018
Study Type : Insect Study
Additional Links
Substances : Bacopa
Diseases : Parkinson's Disease, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Paraquat
[+]

Bacopa monnieri supplements offset paraquat-induced behavioural phenotype and brain oxidative pathways in mice.Jan 14, 2019

Pubmed Data : Cent Nerv Syst Agents Med Chem. 2019 Jan 15. Epub 2019 Jan 15. PMID: 30644349
Article Published Date : Jan 14, 2019
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Brain: Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Paraquat
[+]

Beneficial effects of ascorbic acid to treat lung fibrosis induced by paraquat.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(11):e0205535. Epub 2018 Nov 5. PMID: 30395570
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Fibrosis, Pesticide Toxicity
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation
Problem Substances : Paraquat
[+]

Berberis vulgaris fruit has beneficial effects in rat pulmonary fibrosis induced by paraquat.Jun 30, 2016

Pubmed Data : Biomed Pharmacother. 2016 Jul ;81:329-36. Epub 2016 Apr 26. PMID: 27261610
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Barberry
Diseases : Fibrosis, Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response
Problem Substances : Paraquat
[+]

Mucuna pruriens seed extract treatment significantly reduced the Paraquat induced neurotoxicity.May 31, 2013

Pubmed Data : Neurochem Int. 2013 Jun ;62(8):1039-47. Epub 2013 Apr 3. PMID: 23562769
Article Published Date : May 31, 2013
Study Type : Animal Study
Additional Links
Substances : Mucuna pruriens (aka Velvet Beans)
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Paraquat
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Orally delivered water soluble Coenzyme Q10 blocks on-going neurodegeneration in rats exposed to paraquat.Jan 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Neurosci. 2014 Jan 31 ;15:21. Epub 2014 Jan 31. PMID: 24483602
Article Published Date : Jan 30, 2014
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Paraquat
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Paraquat could negatively influence the learning and memory abilities of developing mice.May 31, 2011

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011 Jun ;29(6):437-9. PMID: 22096857
Article Published Date : May 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Learning disorders, Oxidative Stress, Pesticide Toxicity
Additional Keywords : Risk Factors
Problem Substances : Paraquat
Adverse Pharmacological Actions : Neurotoxic
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Paraquat induced alteration in the metabolites leads to oxidative stress and neurodegeneration in the exposed organism along with movement disorder.Dec 31, 2015

Pubmed Data : Mol Neurobiol. 2016 Jan ;53(1):254-69. Epub 2014 Nov 27. PMID: 25428622
Article Published Date : Dec 31, 2015
Study Type : Insect Study
Additional Links
Diseases : Oxidative Stress, Parkinsonism
Problem Substances : Paraquat
Adverse Pharmacological Actions : Neurotoxic
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Paraquat induced oxidative damage of the male reproductive system.Feb 28, 2017

Pubmed Data : J Biochem Mol Toxicol. 2017 Mar ;31(3). Epub 2016 Oct 20. PMID: 27762473
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Diseases : Lipid Peroxidation, Oxidative Stress, Sperm Quality: Low
Pharmacological Actions : Apoptotic
Problem Substances : Paraquat
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Procyanidin B2 protects rats from paraquat-induced acute lung injury.Sep 30, 2018

Pubmed Data : Immunobiology. 2018 Oct ;223(10):555-561. Epub 2018 Jul 6. PMID: 30025709
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Procyanidin B2
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
Problem Substances : Paraquat
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Protective role of thymoquinone against paraquat-induced hepatotoxicity in mice.May 31, 2018

Pubmed Data : Pestic Biochem Physiol. 2018 Jun ;148:16-21. Epub 2018 Mar 13. PMID: 29891368
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Herbicide Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
Problem Substances : Paraquat
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The anti-inflammatory effect of hesperetin on lung damage induced by paraquat..May 19, 2018

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2018 May 20 ;36(5):336-342. PMID: 29996377
Article Published Date : May 19, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Paraquat
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The results showed that cognitive functions and alterations in the working memory and anxiety levels were detected in mice exposed to cesium-137combined with paraquat exposure. Mar 01, 2015

Pubmed Data : Toxicology. 2015 Mar 2 ;329:73-9. Epub 2015 Jan 17. PMID: 25602925
Article Published Date : Mar 01, 2015
Study Type : Animal Study
Additional Links
Diseases : Learning disorders, Neonatal Diseases and Abnormalities, Radiation-Induced Illness: Cesium-137 Exposure
Additional Keywords : Chernobyl, Environmental Toxicity, Fukushima, Synergistic Toxicity
Problem Substances : Cesium-137, Paraquat
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These findings suggest that methylsulfonylmethane as a natural product attenuates paraquat-induced pulmonary and hepatic oxidative injury.Sep 30, 2013

Pubmed Data : Inflammation. 2013 Oct ;36(5):1111-21. PMID: 23595869
Article Published Date : Sep 30, 2013
Study Type : Animal Study
Additional Links
Substances : MSM (Methylsulfonylmethane)
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Paraquat
[+]

This study showed the protective effects of ellagic acid against paraquat-induced nephrotoxicity.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Kidney Dis. 2016 Jan ;11(1):23-28. PMID: 28174349
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Pesticide Toxicity
Pharmacological Actions : Cytoprotective, Renoprotective
Problem Substances : Paraquat
[+]

Tualang honey may protect against Paraquat induced toxicity in the rat midbrain and lung.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:4605782. Epub 2017 Jan 3. PMID: 28127418
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Tualang Honey
Diseases : Pesticide Toxicity
Pharmacological Actions : Cytoprotective, Neuroprotective Agents
Problem Substances : Paraquat
[+]

Aronia berry concentrate at low doses restores the homeostatic redox environment of neurons treated with paraquat.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:5296271. Epub 2015 Dec 6. PMID: 26770655
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Chokeberry
Diseases : Herbicide Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Herbicide, Paraquat
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Carnosic acid induces anti-inflammatory effects in paraquat-treated SH-SY5Y cells.Dec 31, 2017

Pubmed Data : Mol Neurobiol. 2018 Jan ;55(1):890-897. Epub 2017 Jan 12. PMID: 28083817
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosic Acid
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Heme oxygenase-1 inducer, Interleukin-1 beta downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Paraquat
[+]

Paraquat inhibited differentiation in human neural progenitor cells.Feb 29, 2016

Pubmed Data : Environ Toxicol Pharmacol. 2016 Mar ;42:205-11. Epub 2016 Jan 25. PMID: 26878281
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : paraquat, Pesticide Toxicity
Problem Substances : Paraquat
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Sea buckthorn extract may be used as a potential therapeutic agent for the treatment of various oxidative stress-related diseases.Nov 30, 2013

Pubmed Data : Mol Med Rep. 2013 Dec ;8(6):1852-60. Epub 2013 Oct 16. PMID: 24141985
Article Published Date : Nov 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Sea buckthorn
Diseases : Oxidative Stress, Pesticide Toxicity
Pharmacological Actions : Antioxidants, Nrf2 activation
Additional Keywords : Gene Expression Regulation, Plant Extracts
Problem Substances : Paraquat
[+]

The tea polyphenol epigallocatechin gallate inhibits Escherichia coli by increasing endogenous oxidative stress.Feb 14, 2017

Pubmed Data : Food Chem. 2017 Feb 15 ;217:196-204. Epub 2016 Aug 26. PMID: 27664626
Article Published Date : Feb 14, 2017
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Escherichia coli Infections
Pharmacological Actions : Anti-Bacterial Agents
Problem Substances : Paraquat

Copyright: molekuul / 123RF Stock Photo

Paraquat Related Articles

Herbicide and Pesticide Exposure Linked to Parkinson's Disease
Written by Case Adams, Naturopath
A recent study from UCLA has confirmed that exposure to the herbicide Paraquat is linked with a heightened risk of Parkinson’s disease. Other studies have found that pesticides significantly increase the risk of Parkinson's.

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