Hepatoprotective

Name	AC	CK
Curcumin	122	261
Coffee	10	98
Ginsenosides	32	56
Vitamin E	10	54
Green Tea	13	51
Anthocyanins	21	47
Thymoquinone	26	47
Resveratrol	25	46
Probiotics	10	43
Nigella sativa (aka Black Seed)	18	42
Polyphenols	23	42
Garlic	13	41
Turmeric	17	41
Vitamin C	21	40
Milk Thistle	11	39
Omega-3 Fatty Acids	7	39
Silymarin	11	38
Spirulina	15	37
Berberine	18	36
Melatonin	20	36
Polyunsaturated Fatty Acids (PUFAs)	3	32
Astaxanthin	17	30
DHA (Docosahexaenoic Acid)	6	28
Fermented Foods and Beverages	10	27
Flavonoids	14	26
Ginger	13	26
NAC (N-acetyl-L-cysteine)	9	25
Quercetin	13	25
Vitamin D	9	25
Guduchi	4	24
Rose	13	24
Zataria multiflora	8	24
Puerarin	12	23
Blue Honeysuckle	11	22
Hydroxytyrosol	7	22
Silibinin	9	22
Fucoidan	11	21
Sulforaphane	8	21
Hibiscus sabdariffa	6	20
Mangiferin	10	20
Naringenin	11	20
Reishi Mushroom	6	20
Tea: Black	1	20
Tea: Green	1	20
Blueberry	10	19
Ellagic Acid	10	19
Artichoke	6	18
Pomegranate	9	18
Catechin	5	17
Citrus naringin	9	17
Lycopene	9	17
Moringa oleifera	10	17
Bilberry	4	16
Black Currant	4	16
Chlorogenic Acid	8	16
Asiatic Acid	8	15
Chokeberry	8	15
Chrysin	8	15
EGCG (Epigallocatechin gallate)	9	15
Olive leaf extract	8	15
Alpha-Lipoic Acid	7	14
Broccoli	3	14
Dandelion	7	14
Flaxseed	3	14
Ginseng (Korean)	4	14
Grape Seed Extract	7	14
Hesperidin	7	14
Honey	7	14
Selenium	7	14
Walnut	7	14
Apigenin	5	13
Luteolin	5	13
Xanthohumol	7	13
Apple Polyphenols	6	12
Black Tea	6	12
Camel Milk	6	12
Cannabidiol	6	12
Crocin	6	12
Fenugreek	6	12
Fisetin	6	12
Gingerol	6	12
Lactobacillus plantarum	6	12
Lotus	7	12
Magnesium	2	12
Sea buckthorn	6	12
Sweet Potato: Purple	6	12
Turmeric: Fermented	2	12
Yoghurt	2	12
Coenzyme Q10	6	11
Diallyl sulfide	6	11
Lychee	6	11
Rosemary	6	11
Royal Jelly	6	11
Shikonin	6	11
Caffeic acid phenethyl ester	5	10
Capsaicin	5	10
Diosmin	5	10
Ginkgo biloba	5	10
Hawthorn	5	10
Holy Basil	1	10
Menatetrenone	1	10
Multivitamin	1	10
Oolong tea	1	10
Rutin	5	10
Strawberry	6	10
Tetrahydrocurcumin	6	10
Ursolic Acid	6	10
Vitamin K2	1	10
Vitamin K2: Menaquinones (MK-4-14)	1	10
Bael	5	9
Garden Cress (Lepidium sativum)	3	9
Genipin	5	9
Ginseng	5	9
Indole-3-Carbinol	5	9
Licorice	5	9
Olive Oil	5	9
Amla Fruit	4	8
Carrot	4	8
Cordyceps sinensis	4	8
Genistein	4	8
Geraniol	4	8
Grape	4	8
Litchi	4	8
Noni	4	8
Oleuropein	4	8
Olive	4	8
Paeoniflorin	4	8
Pomegranate Peel	4	8
Radish	5	8
Solanum nigrum (black nightshade)	4	8
Astragaloside	4	7
Beta-Caryophyllene	4	7
Betulinic acid	4	7
Caffeic Acid	4	7
Carvacrol	4	7
Lactobacillus fermentum	4	7
Lactobacillus rhamnosus GG	4	7
Nettle	4	7
Nobiletin	4	7
Palash	4	7
Panax Notoginseng	4	7
Saffron	4	7
Antrodia camphorata	3	6
Ayurvedic formulation: Liv52	3	6
Beet	3	6
Berries: All	3	6
Bitter Melon	3	6
Blackberry	4	6
Burdock	3	6
Carnosic Acid	3	6
Celery	3	6
Chicory	3	6
Cranberry	3	6
Dates	3	6
Dragon Fruit	3	6
EPA (Eicosapentaenoic Acid)	3	6
Folic Acid	3	6
Hydrogen Water	3	6
Jujube	3	6
Juniper	3	6
Krill	3	6
Lactobacillus paracasei	3	6
Onion	3	6
Passion Flower	3	6
Phosphatidylcholine	3	6
Prickly Pear Cactus	4	6
Propolis: Bee	3	6
Pterostilbene	3	6
Pumpkin Seed Oil/Meal	3	6
Pycnogenol (Pine Bark)	3	6
Sesamol	3	6
Shiitake Mushroom	3	6
Stevia	3	6
White Tea	3	6
Yellow Tea	3	6
Zinc	3	6
Carotenoids	3	5
Fig	3	5
Gallic Acid	3	5
Purslane	4	5
Red Cabbage	3	5
Rosemaric Acid	3	5
Sage	3	5
Tanshinone IIA	4	5
Thistle	4	5
Wheat Grass	3	5
Aloe Vera	2	4
Angelica	2	4
Arctigenin	2	4
Ashwagandha	2	4
Baccharis trimera	2	4
Baicalein	2	4
Barley	2	4
Basil	2	4
Bee Propolis	2	4
Beeswax	2	4
Beta Sitosterol	2	4
Bifidobacterium Longum	2	4
Bitter Apple	2	4
Black Raspberry	2	4
Chaga Mushroom (Inonotus obliquus)	3	4
Chamomile	2	4
Chlorella (Algae)	2	4
Choline	2	4
Citrus Peel	2	4
Coconut Water	2	4
Cordyceps Militaris	2	4
Coriandrum sativum	2	4
Corn: Purple	2	4
D-Limonene	2	4
Date Seeds	2	4
Dill	2	4
Embelia ribes	2	4
FOS (Fructooligosaccharides)	2	4
Flaxseed Oil	2	4
Garlic: Aged	2	4
Gastrodin	2	4
Ginseng (American)	2	4
Glycyrrhizin	2	4
Goji	2	4
Henna	2	4
Horehound	2	4
Hu Zhang (Polygonum cuspidatum)	2	4
Isoliquiritigenin	2	4
Kimchi	2	4
Lignans	3	4
Lingonberry	2	4
Lutein	2	4
Marjoram	2	4
Myricetin	2	4
Panax Ginseng	2	4
Piceatannol	2	4
Piperine	2	4
Policosanol	2	4
Pomegranate Seed	2	4
Potato	2	4
Procyanidin B2	2	4
Pumpkin Seeds	2	4
Rhubarb	2	4
Salvia miltiorrhiza	2	4
Stigmasterol	2	4
Syrian rue	2	4
Tamarind	3	4
Taurine	2	4
Thyme	2	4
Verbascoside	2	4
Vitex negundo	2	4
Yeast	2	4
Allicin	2	3
Astragalus	2	3
Barberry	2	3
Bee Venom	2	3
Cannabinoids	2	3
Cryptoxanthin	2	3
Cucumber	2	3
Diosgenin	2	3
Ferulic acid	2	3
Honokiol	2	3
Huperzine	2	3
Kudzu	2	3
Lion's Mane (Hericium Erinaceus)	2	3
Mulberry	2	3
Oleanolic acid	2	3
Phloretin	2	3
Phyllanthus urinaria	2	3
Pine Bark Extract	2	3
Punicalagin	2	3
Thymol	2	3
Water: Deep Sea	2	3
2-Methoxyestradiol	1	2
6-Shogaol	1	2
Acai	1	2
Ajwain	1	2
Almond	1	2
Amygdalin (laetrile)	1	2
Andrographis	1	2
Anise	1	2
Apocynin	1	2
Apple Cider Vinegar	1	2
Apples	1	2
Apricot	1	2
Apricot Kernel	1	2
Arginine	1	2
Artesunate	1	2
Asparagus	1	2
Avocado	1	2
Bacopa	1	2
Bamboo	1	2
Banana Peel	1	2
Banana Stem	1	2
Bay leaf	1	2
Berbamine	1	2
Bisdemethoxycurcumin	1	2
Bitter Orange	1	2
Black Tea Theaflavins	1	2
Boron	1	2
Broccoli Sprouts	1	2
Bromelain	1	2
Butterbur	1	2
Caffeine	1	2
Calcium	1	2
Cannabis	1	2
Carnosine	1	2
Celery Oil	1	2
Celery seed	1	2
Celosia cristata (cockscomb)	1	2
Centella asiatica	1	2
Cherry: All Varieties	1	2
Chickpea	1	2
Chrysanthemum Indicum	1	2
Cinnamon	1	2
Cissus quadrangularis	1	2
Cloudberry	1	2
Cocoa Butter	1	2
Coconut Oil	1	2
Coffee: Green/Unroasted	1	2
Copper	1	2
Coptidis rhizoma	1	2
Crowberry	1	2
Cucurbitacin B	1	2
Cucurbitacin E	1	2
Cumin	1	2
Cysteine (see N-Acetylcysteine)	1	2
Dibenzoylmethane (DBM)	1	2
Earthworms	1	2
Echinacea	1	2
Eggplant	1	2
Elderberry	1	2
Emodin	1	2
Eriodictyol	1	2
Feijoa	1	2
Feverfew	1	2
Fish Oil	1	2
Flowers	1	2
Frankincense	1	2
Fruit: All	1	2
Gamma-Oryzanol	1	2
Gardenia	1	2
Geranium	1	2
Gold (nanoparticles)	1	2
Goldenseal	1	2
Guarana	1	2
Guava	1	2
Gynostemma	2	2
Helenalin	1	2
Hibiscus rosa-sinensis	1	2
Histidine	1	2
Homeopathic Medicine: All	1	2
Homeopathic Medicine: Lycopodium	1	2
Honeydew (melon)	1	2
Hops	1	2
Humic Acid	1	2
Isoquercitrin	1	2
Kefir	1	2
Kombucha Tea	2	2
Lactobacillus casei	1	2
Lactobacillus casei: Shirota	1	2
Lactobacillus probiotics	1	2
Lactobacillus reuteri	1	2
Lactobacillus rhamnosus	1	2
Lactobacillus salivarius	1	2
Lecithin	1	2
Ligustrazine	1	2
Linden (Tilia)	1	2
Long Pepper	1	2
Loquat	1	2
Loquat Seeds	1	2
MSM (Methylsulfonylmethane)	1	2
Maca	1	2
Magnesium Sulfate	1	2
Magnolol	1	2
Maitake Mushroom	1	2
Mango	1	2
Mangosteen	1	2
Manuka Honey	1	2
Mastic gum	1	2
Medicinal Mushrooms	1	2
Medium Chain Triglycerides	1	2
Mint	1	2
Miso	1	2
Modified Arabinoxylan Rice Bran (MGN-3)	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Myrica rubra	1	2
Nicotinamide adenine dinucleotide (NADH)	1	2
Nutmeg	1	2
Oak	1	2
Oats	1	2
Okra	1	2
Oleic acid	1	2
Olives	1	2
Orange	1	2
Oregano	1	2
Oyster Mushroom	1	2
Palmitoylethanolamide	1	2
Papaya	1	2
Papaya: Fermented	1	2
Parsley	1	2
Parthenolide	1	2
Pectin	1	2
Peppermint	1	2
Phellinus Linteus	2	2
Phospholipids	1	2
Phyllanthus emblica	1	2
Pine Needle	1	2
Pine Nut	1	2
Piper cubeba (Cubeb)	1	2
Plant Stem Cells	1	2
Plantago	1	2
Plantago major	1	2
Pleurotus nebrodensis	1	2
Proanthocyanidins	1	2
Protein Supplement	1	2
Pterocarpus marsupium	1	2
Pueraria mirifica	1	2
Purple Carrots	1	2
Rambutan	1	2
Raspberry	1	2
Red Sage	1	2
Rice	1	2
Rice Bran	1	2
Rice: Brown	1	2
Rice: Parboiled	1	2
Rooibos	1	2
Rose Hips	1	2
Rosmarinic acid	1	2
SAMe (S-adenosylmethionine)	1	2
Saikosaponin	1	2
Sessile Joyweed	1	2
Shallot	1	2
Skullcap: Chinese	1	2
Soy	1	2
Soybean: Black	1	2
Spearmint	1	2
St. Johns Wort	1	2
Star Fruit	1	2
Stilbenes	1	2
Sweet Cherry	1	2
Sweet Potato	1	2
Tannic Acid	1	2
Taro	1	2
Toona sinensis	1	2
Tribulus	1	2
Tyrosine	1	2
Vanillin	1	2
Virgin Coconut Oil	1	2
Vitamin E: Gamma-tocotrienol	1	2
Vitamin E: alpha tocopherol	1	2
Vitexins	1	2
Water: Deuterium Depleted	1	2
Water: Electrolyzed Reduced	1	2
Watercress	1	2
Xanthones	1	2
Yellow Sweet Clover (Melilotus officinalis)	1	2
Zerumbone	1	2
Agrimony	1	1
Beta-Elemene	1	1
Caraway	1	1
Cocoa	1	1
Coriandor	1	1
Crimini Mushroom	1	1
Curcuminoids	1	1
Cyperus longus	1	1
Eugenol	1	1
Fucoxanthin	1	1
Haritaki (Terminalia chebula)	1	1
Lavender	1	1
Lupeol	1	1
Methionine	1	1
Mugwort	1	1
Mushrooms: All	1	1
Muskmelon	1	1
Mustard: Field/Turnip	1	1
Persimmon	1	1
Prebiotics	1	1
Rice: Black	1	1
Vitamin A	1	1
White Mulberry	1	1
Wormwood	1	1

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2015 May ;94(20):e758. PMID: 25997043

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Pak J Med Sci. 2017 Jul-Aug;33(4):931-936. PMID: 29067068

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asia Pac J Clin Nutr. 2016 Dec ;25(4):767-775. PMID: 27702720

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Coffee

Diseases : Liver Disease

Pharmacological Actions : Enzyme Inhibitors, Hepatoprotective

[+]

Higher intake and serum levels of most carotenoids were associated with lower odds of having NAFLD.May 16, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

N-acetyl cysteine may have a protective effect against reperfusion injury in liver transplant recipients. Nov 01, 2008

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Pubmed Data : Transplant Proc. 2008 Nov;40(9):2978-80. PMID: 19010165

Pubmed Data : J Interferon Cytokine Res. 2017 Nov ;37(11):480-487. PMID: 29135373

Article Published Date : Oct 31, 2017

Study Type : Human Study

Additional Links

Substances : Silymarin

Diseases : Hepatitis C, Liver Disease

Pharmacological Actions : Hepatoprotective

[+]

Supplementation at a high dosage of 6 g daily in NAFLD patients has strong and multiple beneficial metabolic effects and improves their health-related quality of life.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Cell Biochem. 2019 Sep ;120(9):15989-15996. Epub 2019 Jun 6. PMID: 31168845

Article Published Date : Aug 31, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin, Piperine

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective, Hypolipidemic

[+]

Tinospora cordifolia has a protective effect on hepatic and gastrointestinal toxicity induced by chronic and moderate alcoholism.Dec 31, 2015

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Pubmed Data : Alcohol Alcohol. 2016 Jan ;51(1):1-10. Epub 2015 Aug 19. PMID: 26589585

Pubmed Data : Environ Toxicol. 2017 Feb ;32(2):630-644. Epub 2016 Mar 28. PMID: 28071871

Article Published Date : Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Case Reports Hepatol. 2014 ;2014:697359. Epub 2014 Sep 3. PMID: 25374729

Article Published Date : Dec 31, 2013

Study Type : Human: Case Report

Additional Links

Diseases : Liver Damage: Drug-Induced

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Significant Treatment Outcome

Problem Substances : Fluconazole

[+]

N-acetylcysteine in the management of acute liver failure from sickle cell hepatic crisis.Jul 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Pharmacognosy Res. 2013 Oct ;5(4):271-6. PMID: 24174821

Article Published Date : Sep 30, 2013

Study Type : Animal Study

Additional Links

Substances : Fig

Diseases : Liver Damage: Drug-Induced, Oxidative Stress

Pharmacological Actions : Hepatoprotective

Additional Keywords : Plant Extracts

Problem Substances : Isoniazid, Paracetamol

[+]

"Vitamin E protects against oxidative damage caused by formaldehyde in the liver and plasma of rats."Oct 01, 2006

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Pubmed Data : Mol Cell Biochem. 2006 Oct ;290(1-2):61-7. Epub 2006 Aug 26. PMID: 16937016

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Pubmed Data : J Steroid Biochem Mol Biol. 2016 Apr 12. Epub 2016 Apr 12. PMID: 27084531

Pubmed Data : Phytomedicine. 2019 Jan 9 ;58:152824. Epub 2019 Jan 9. PMID: 30836218

Article Published Date : Jan 08, 2019

Study Type : Animal Study

Additional Links

Substances : Kudzu, Milk Thistle

Diseases : Alcoholic Liver Disease

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic

[+]

A combination strategy of thymoquinone and curcumin might be considered as a potential antidote in combating liver injury induced by acetaminophen.Mar 04, 2019

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Pubmed Data : Folia Morphol (Warsz). 2019 Mar 5. Epub 2019 Mar 5. PMID: 30835338

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Pubmed Data : Phytother Res. 2015 Oct ;29(10):1577-84. Epub 2015 Jul 14. PMID: 26178909

A methanolic extract of pomegranate peel ameliorated the hepatic damage caused by acetaminophen.Jun 30, 2016

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Pubmed Data : J Pak Med Assoc. 2016 Jul ;66(7):859-63. PMID: 27427136

Article Published Date : Jun 30, 2016

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Pubmed Data : Food Funct. 2017 Feb 22 ;8(2):816-822. PMID: 28124048

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Pubmed Data : Am J Chin Med. 2000 ;28(2):163-73. PMID: 10999435

Article Published Date : Dec 31, 1999

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Pubmed Data : Planta Med. 2009 Nov ;75(14):1463-9. Epub 2009 Jun 22. PMID: 19548187

Article Published Date : Oct 31, 2009

Study Type : Animal Study

Additional Links

Substances : Verbascoside

Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage

Pharmacological Actions : Antioxidants, Hepatoprotective, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

[+]

Activation of cannabinoid system may have protective actions on both liver and brain induced by cocaine, minimizing inflammatory injury promoted by cocaine.Dec 31, 2014

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Pubmed Data : Mediators Inflamm. 2015 ;2015:523418. Epub 2015 Apr 27. PMID: 25999668

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Cocaine Toxicity , Drug Abuse

Pharmacological Actions : Hepatoprotective, Neuroprotective Agents

[+]

Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.Dec 31, 2017

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Pubmed Data : Int Immunopharmacol. 2018 Jan ;54:125-130. Epub 2017 Nov 9. PMID: 29128856

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Chlorogenic Acid

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Pubmed Data : Environ Toxicol Pharmacol. 2018 Feb 23 ;59:17-23. Epub 2018 Feb 23. PMID: 29500983

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Pubmed Data : Aging (Albany NY). 2019 Dec 6 ;11(23):11084-11110. Epub 2019 Dec 6. PMID: 31806859

Article Published Date : Dec 05, 2019

Study Type : Animal Study

Additional Links

Substances : Mangosteen

Diseases : Aging, Inflammation, Liver Damage, Metabolic Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, MicroRNA modulator

[+]

Ameliorating efficacy of eugenol against metanil yellow induced toxicity.Feb 06, 2019

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Pubmed Data : Food Chem Toxicol. 2019 Feb 7 ;126:34-40. Epub 2019 Feb 7. PMID: 30738991

Article Published Date : Feb 06, 2019

Study Type : Animal Study

Additional Links

Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective

Problem Substances : Food Colorings

[+]

Ameliorative effect of curcumin on hepatotoxicity induced by chloroquine phosphate.Aug 31, 2010

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Pubmed Data : Environ Toxicol Pharmacol. 2010 Sep ;30(2):103-9. Epub 2010 May 20. PMID: 21787638

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Pubmed Data : Int J Mol Sci. 2019 Apr 3 ;20(7). Epub 2019 Apr 3. PMID: 30987167

Article Published Date : Apr 02, 2019

Study Type : Animal Study

Additional Links

Substances : Spinach

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Plant Extracts

[+]

Ameliorative effects of Compound K and ginsenoside Rh1 on non-alcoholic fatty liver disease in rats.Jan 19, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Nagoya J Med Sci. 2015 Feb ;77(1-2):145-53. PMID: 25797979

Pubmed Data : Nat Prod Res. 2016 Mar ;30(6):715-9. Epub 2015 May 15. PMID: 25978515

Article Published Date : Feb 29, 2016

Study Type : Animal Study

Additional Links

Substances : Tamarind

Pharmacological Actions : Hepatoprotective

Problem Substances : Tubercular Drugs

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An aqueous extract of white clover was protective against the hepatotoxicity induced by acetaminophen.Aug 31, 2019

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Pubmed Data : J Food Biochem. 2019 Sep ;43(9):e12963. Epub 2019 Jul 2. PMID: 31489655

Article Published Date : Aug 31, 2019

Study Type : Animal Study

Additional Links

Substances : White Clover

Diseases : Acetaminophen (Tylenol) Toxicity

Pharmacological Actions : Antioxidants, Hepatoprotective

Problem Substances : Acetaminophen, Paracetamol

[+]

An extract of Fragaria ananassa had a protective effect against cadmium chloride toxicity upon the liver. Jan 21, 2017

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Pubmed Data : Toxicol Mech Methods. 2017 Jan 22:1-27. Epub 2017 Jan 22. PMID: 28110594

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Pubmed Data : Molecules. 2014 ;19(10):15440-51. Epub 2014 Sep 26. PMID: 25264831

Article Published Date : Dec 31, 2013

Anise seed possesses protective effects against carbon tetrachloride (CCl4)-induced toxicity.Jan 31, 2015

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Pubmed Data : Iran J Basic Med Sci. 2015 Feb ;18(2):205-11. PMID: 25825639

Article Published Date : Jan 31, 2015

Study Type : Animal Study

Additional Links

Substances : Anise

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Essential Oils

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Anthocyanin from Lonicera caerulea can be used as a dietary health supplement for alcoholic steatohepatitis.Jun 09, 2019

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Antidiabetic activity and chemical composition of Sanbai melon seed oil.Dec 31, 2017

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Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:5434156. Epub 2018 May 2. PMID: 29853958

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Pubmed Data : Chem Biol Interact. 2018 Aug 21 ;294:91-100. Epub 2018 Aug 21. PMID: 30138605

Article Published Date : Aug 20, 2018

Study Type : Animal Study

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Substances : Berberine

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

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Antioxidant and hepato-preventive effect of Citrus aurantium extract against carbon tetrachloride-induced hepatotoxicity.Sep 30, 2019

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Pubmed Data : Arch Physiol Biochem. 2019 Oct ;125(4):332-343. Epub 2018 Apr 17. PMID: 29663826

Article Published Date : Sep 30, 2019

Study Type : Animal Study

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Substances : Bitter Orange

Diseases : Chemically-Induced Liver Damage, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective

Additional Keywords : Plant Extracts

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Antioxidant and hepatoprotective potential of Lawsonia inermis L. leaves against 2-acetylaminofluorene induced hepatic damage.Jan 17, 2017

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Pubmed Data : World J Gastroenterol. 2006 Nov 14 ;12(42):6835-41. PMID: 17106933

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Pubmed Data : Curr Ther Res Clin Exp. 2015 Dec ;77:73-8. Epub 2015 May 27. PMID: 26543508

Article Published Date : Nov 30, 2015

Study Type : Animal Study

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Substances : Burdock

Diseases : Acetaminophen (Tylenol) Toxicity

Pharmacological Actions : Hepatoprotective

Problem Substances : Acetaminophen, Paracetamol

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Arctium lappa root extract prevents lead-induced liver injury.Nov 23, 2019

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View the Evidence: 1815 Abstracts with Hepatoprotective Research

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Coffee consumption can significantly reduce the risk for hepatic fibrosis and cirrhosis.Dec 31, 2014

Coffee consumption could lower the risks of liver cancers, liver diseases and liver cirrhosis.Dec 31, 2015

Efficacy and safety of total glucosides of paeony combined with methotrexate and leflunomide for active rheumatoid arthritis.Dec 31, 2018

Green tea intake reduces the risk of liver disease.Dec 31, 2014

Physical activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD.May 03, 2016

Polyunsaturated fatty acids supplementation can improve liver steatosis and liver functions.Dec 22, 2016

Prophylactic therapy of milk thistle on anti-tuberculosis drug-induced liver injury.Dec 31, 2018

Studies on coffee and NAFLD suggest that coffee consumption could have a protective role on fibrosis.Mar 29, 2016

Synergistic and hepatoprotective effect of total glucosides of paeony on ankylosing spondylitis.Dec 31, 2018

Tanshinone IIA can effectively improve liver fibrosis and liver function.Dec 31, 2018

These results found a significantly decreased risk of NAFLD among coffee drinkers and significantly decreased risk of liver fibrosis.Nov 06, 2016

Vitamin E significantly improved liver function and histologic changes in patients with NAFLD/NASH.Jun 30, 2015

8 weeks of provision of a diet low in free sugar content compared with usual diet resulted in significant improvement in hepatic steatosis.Jan 21, 2019

A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients. Apr 30, 2015

A multivitamin and phospholipids complex protects the hepatic cells from androgenic-anabolic-steroids-induced toxicity.Jan 01, 2008

A probiotic yogurt demonstrates a significant rate of minimal hepatic encephalopathy reversal. Jul 01, 2008

A vitamin K2 preparation inhibits the development of liver cancer in patients with type C cirrhosis. Sep 01, 2010

Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.Oct 24, 2019

An improved diet is particularly important for individuals with a high genetic risk for NAFLD.Mar 27, 2018

Artichoke leaf extracts have benefits in the management of NASH.Dec 31, 2015

Beneficial effects of curcumin supplementation were observed in decreasing disease activity scores and severity of cirrhosis in patients with cirrhosis.Feb 02, 2020

Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.Nov 30, 2018

Black cumin seeds decreased Methotrexate hepatotoxicity and improved survival in children with ALLMar 19, 2015

Comparative studies on the hypolipidemic, antioxidant and hepatoprotective activities of catechin-enriched green and oolong tea Jan 30, 2018

Consumption of hibiscus sabdariffa extracts reduced obesity, abdominal fat, serum FFA and improved liver steatosis.Mar 31, 2014

Curcuma longa (turmeric) and tinospora cordifolia (guduchi) prevents antibiotic-induced liver damage in patients with tubercolosis. Aug 14, 2008

Curcumin alleviates ethanol-induced oxidative damage in liver cells. Jan 18, 2010

Curcumin prevented the development of immunological alterations in NAFLD.Dec 31, 2016

Curcumin-galactomannoside complex offered significant hepatoprotective effects to attenuate alcohol induced alterations to hepatic function markers.Dec 31, 2017

DHA supplementation improves liver steatosis in children with NAFLD. Oct 31, 2013

Diets with a higher intake of nuts may be associated with a decreased risk of NAFLD.Sep 03, 2019

Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity.Mar 14, 2017

Electroacupuncture and aerobic interval training exercise are potent modalities that improve liver functions in people with Nonalcoholic fatty liver disease.Oct 28, 2019

Fermented garlic extracts might be effective and safe management options for mild hepatic dysfunction.Jul 31, 2017

Fermented turmeric powder is well-tolerated and effective in subjects with elevated alanine transaminase levels.Dec 31, 2012

Flaxseed oil in the context of a weight loss program ameliorates fatty liver grade in patients with non-alcoholic fatty liver disease.Jan 28, 2020

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

Fructose restriction decreased liver fat, visceral fat, and de novo lipogenesis, and improved insulin kinetics in children with obesity.May 31, 2017

Garlic may reduce the amount of fat in the liver and prevent or delay the progression of NAFLD.Dec 31, 2015

Green tea extract therapy resulted in significant improvement in metabolic, chemical, inflammatory and radiological parameters of NAFLD patients.Jun 30, 2017

Hesperidin supplementation accompanied with lifestyle modification is superior to lifestyle modification alone in management of NAFLD.Jun 30, 2019

High intake of magnesium may be associated with reduced risks of fatty liver disease and prediabetes.Apr 01, 2018

Higher coffee consumption was associated with lower risk of elevated aminotransferase concentration in Korean adults.Nov 30, 2016

Higher intake and serum levels of most carotenoids were associated with lower odds of having NAFLD.May 16, 2019

Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease.Apr 10, 2019

Hydrogen-rich water significantly attenuates oxidative stress in chronic hepatitis B patients.Sep 30, 2013

Korean Red Ginseng could be used as a complementary therapy for chronic hepatitis B.Nov 30, 2016

Maintenance of high cardiorespiratory fitness and stability of body weight are critical public health considerations for the treatment of NAFLD.Jul 20, 2016

n-3 PUFA treatment is safe and efficacious in obese children with NAFLD and can improve ultrasonographic findings and the elevated transaminase levels.Jun 04, 2015

N-acetyl cysteine may have a protective effect against reperfusion injury in liver transplant recipients. Nov 01, 2008

N. sativa seed oil seems to be safe and improve liver steatosis and injury and blood levels of triglycerides, LDL-C and HDL-C in the NAFLD patients.Apr 23, 2019

Nigella sativa seed oil supplements may decrease the liver enzymes and lipid profiles in the patients with NAFLD.Nov 30, 2019

Probiotic compounds can be effective in improving pediatric NAFLD.Oct 12, 2016

Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.Oct 31, 2017

Short-term supplementation with Curcumin led to an improvement in different features of NAFLD.Jun 07, 2016

Short-term vitamin E treatment significantly improves abnormal liver enzyme levels in NAFLD patients with metabolic syndrome.Nov 30, 2015

Silibinin could be beneficial in preventing drug-induced liver injury in tuberculosis treatments. Dec 31, 2014

Silymarin has an efficacy to prevent liver injury from standard combined antituberculosis drugs without significant adverse effects.Dec 31, 2014

Silymarin in high dose is a good choice for improvement of liver biochemical profile and QoL in chronic hepatitis C virus cirrhotic patients.Oct 31, 2017

Supplementation at a high dosage of 6 g daily in NAFLD patients has strong and multiple beneficial metabolic effects and improves their health-related quality of life.Dec 31, 2013

Supplementation with sulforaphane rich broccoli sprout extract could improve liver function through reduction of oxidative stress.Nov 20, 2015

The present intervention demonstrated the antioxidation, anti-aging and hepatoprotective nature of Ganoderma lucidum.Nov 30, 2017

The results suggest that quercetin-rich onion may be beneficial for preventing obesity and improving liver function.Dec 27, 2019

These observations clearly indicate the beneficial effects of O. sanctum on various biochemical parameters in young overweight or obese subjects.Jun 30, 2017

This study suggested beneficial effects of combined curcuminoids and piperine supplementation on disease severity in patients with NAFLD.Aug 31, 2019

Tinospora cordifolia has a protective effect on hepatic and gastrointestinal toxicity induced by chronic and moderate alcoholism.Dec 31, 2015

Treatment of non-alcoholic steatohepatitis patients with vitamin D.Sep 28, 2018

Turmeric and chicory seed supplementation can be significantly useful in management of NAFLD risk factors.Oct 31, 2019

Vitamin E and C intake may be protective from NAFLD-related liver damage.Jul 03, 2019

Vitamin E and hydroxytyrosol may be a promising strategy that could be easily diet integrated to improve NAFLD-related liver damage in children.Feb 10, 2019

Vitamin E is an effective treatment for nonalcoholic steatohepatitis in HIV mono-infected patients.Oct 15, 2019

Yogurt improves insulin resistance and liver fat in obese women with nonalcoholic fatty liver disease and metabolic syndrome.May 31, 2019

Hepatoprotective

View the Evidence:
1815 Abstracts with Hepatoprotective Research