Insulin-releasing

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35 Substances Researched for Insulin-releasing
NameACCKFocus
Moringa oleifera212Locked
Lactobacillus reuteri110Locked
Probiotics110Locked
Coriandrum sativum24Locked
Ginger24Locked
Acorus calamus12Locked
Agrimony12Locked
Chicory12Locked
Coffee22Locked
Curcumin12Locked
Fucoidan12Locked
Garlic12Locked
Gotu Kola12Locked
Gymnema Sylvestre12Locked
Noni12Locked
Phellinus Linteus12Locked
Stevia12Locked
Ursolic Acid12Locked
Andrographis11Locked
Apricot11Locked
Banaba11Locked
Bitter Melon11Locked
Blackberries11Locked
Cafestol11Locked
Caffeic Acid11Locked
Cocoa11Locked
Eggplant11Locked
Flavonoids11Locked
Gallic Acid11Locked
Ginseng (American)11Locked
Grapes11Locked
Green Tea11Locked
Lotus 11Locked
Polyphenols11Locked
Resveratrol11Locked

View the Evidence:
43 Abstracts with Insulin-releasing Research

[+]

Enrichment of gut microbiota with lactobacillus reuteri increases insulin secretionJun 16, 2015

Pubmed Data : Diabetes Care. 2015 Jun 17. Epub 2015 Jun 17. PMID: 26084343
Article Published Date : Jun 16, 2015
Study Type : Human Study
Additional Links
Substances : Lactobacillus reuteri, Probiotics
Diseases : Insulin: Low
Pharmacological Actions : Insulin-releasing
Additional Keywords : Microbiota
[+]

Momordica charantia administration improves insulin secretion in type 2 diabetes mellitus.Feb 11, 2018

Pubmed Data : J Med Food. 2018 Feb 12. Epub 2018 Feb 12. PMID: 29431598
Article Published Date : Feb 11, 2018
Study Type : Human Study
Additional Links
Substances : Bitter Melon
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

Moringa oleifera leaf may be a potential agent in the treatment of type 2 diabetes.Feb 29, 2016

Pubmed Data : J Med Assoc Thai. 2016 Mar ;99(3):308-13. PMID: 27276742
Article Published Date : Feb 29, 2016
Study Type : Human Study
Additional Links
Substances : Moringa oleifera
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
Additional Keywords : Plant Extracts
[+]

Acorus calamus has insulin releasing and alpha-glucosidase inhibitory activity, confirming its traditional use in American and Indonesia for diabetes. Jan 04, 2010

Pubmed Data : J Ethnopharmacol. 2010 Jan 4. Epub 2010 Jan 4. PMID: 20051258
Article Published Date : Jan 04, 2010
Study Type : Animal Study
Additional Links
Substances : Acorus calamus
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Alpha-glucosidase inhibitor , Insulin-releasing
Additional Keywords : Science Confirms Tradition
[+]

Agrimony exhibits antihyperglycaemic, insulin-releasing and insulin-like activity. Jul 01, 1998

Pubmed Data : Br J Nutr. 1998 Jul;80(1):109-14. PMID: 9797650
Article Published Date : Jul 01, 1998
Study Type : Animal Study
Additional Links
Substances : Agrimony
Diseases : Diabetes Mellitus: Type 1, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents, Insulin-mimetic, Insulin-releasing
[+]

Anthocyanin-rich purple corn extract exerted anti-diabetic effects through protection of pancreatic β-cells and increase of insulin secretion.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2015 Feb ;9(1):22-9. Epub 2015 Jan 28. PMID: 25671064
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Corn: Purple
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing, Pancreato Protective Agents
[+]

Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats.Dec 31, 2003

Pubmed Data : J Pharm Pharmacol. 2004 Jan ;56(1):101-5. PMID: 14980006
Article Published Date : Dec 31, 2003
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Diabetes Mellitus: Type 1: Prevention, Hypertension
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Phytotherapy
Problem Substances : Insulin
[+]

Black seed thymoquinone improved insulin secretion, hepatic glycogen storage, and oxidative stress in streptozotocin-induced diabetic male wistar rats.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8104165. Epub 2018 Mar 4. PMID: 29686746
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed), Thymoquinone
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Insulin-releasing
[+]

Butea monosperma extract significantly reduced blood glucose by 40% and increased plasma insulin levels by 37% in diabetic rats.Jul 31, 2014

Pubmed Data : Pharm Biol. 2014 Aug ;52(8):1021-7. Epub 2014 Mar 12. PMID: 24617860
Article Published Date : Jul 31, 2014
Study Type : Animal Study
Additional Links
Substances : Palash
Diseases : Diabetic Complications, Dyslipidemias
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

Cafestol may contribute to the reduced risk of developing type-2 diabetes in coffee consumers.Jul 31, 2017

Pubmed Data : J Nat Prod. 2017 Aug 1. Epub 2017 Aug 1. PMID: 28763212
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cafestol, Coffee
Diseases : Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Risk Reduction
[+]

Chicoric acid exhibits antidiabetic action throug enhancing insulin release and glucose intake.Dec 05, 2008

Pubmed Data : Biochem Biophys Res Commun. 2008 Dec 5;377(1):131-5. Epub 2008 Oct 1. PMID: 18834859
Article Published Date : Dec 05, 2008
Study Type : Animal Study
Additional Links
Substances : Chicory
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Coriadium sativum has antihyperglycaemic, insulin-releasing and insulin-like activity. Mar 01, 1999

Pubmed Data : Br J Nutr. 1999 Mar;81(3):203-9. PMID: 10434846
Article Published Date : Mar 01, 1999
Study Type : Animal Study
Additional Links
Substances : Coriandrum sativum
Diseases : Diabetes Mellitus: Type 1, Hyperglycemia
Pharmacological Actions : Insulin-mimetic, Insulin-releasing, Insulinotrophic
[+]

Coriander seed may stimulate insulin release from pancreatic beta cells in a type 1 diabetic rat model.Mar 01, 2009

Pubmed Data : Phytother Res. 2009 Mar;23(3):404-6. PMID: 19003941
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Coriandrum sativum
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing, Insulinotrophic
Additional Keywords : Plant Extracts
[+]

Curcumin has an insulin releasing effect in rat-isolated pancreatic islets.Aug 01, 2010

Pubmed Data : Angiology. 2010 Aug;61(6):557-66. Epub 2010 Apr 14. PMID: 20395228
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Diabetes Mellitus: Type 1, Insulin: Low
Pharmacological Actions : Insulin-releasing
[+]

Dietary garlic and especially ginger have anti-diabetic effects. Mar 01, 2008

Pubmed Data : J Med Food. 2008 Mar;11(1):152-9. PMID: 18361751
Article Published Date : Mar 01, 2008
Study Type : Animal Study
Additional Links
Substances : Garlic, Ginger
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
Additional Keywords : Insulinotrophic
[+]

Eriodictyol stimulates insulin secretion.Feb 04, 2018

Pubmed Data : Eur J Pharmacol. 2018 Feb 5 ;820:245-255. Epub 2017 Dec 8. PMID: 29229531
Article Published Date : Feb 04, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Fucoidan may stimulate insulin secretion and provide pancreatic protection via the cAMP signaling pathway, in vivo and in vitro.Aug 31, 2015

Pubmed Data : Mol Med Rep. 2015 Sep ;12(3):4501-7. Epub 2015 Jun 23. PMID: 26130492
Article Published Date : Aug 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Pancreatic Diseases
Pharmacological Actions : Insulin-releasing, Pancreato Protective Agents
Additional Keywords : Dose Response
[+]

Gymnena sylvestre stimulates insulin release.Nov 01, 1999

Pubmed Data : J Endocrinol. 1999 Nov;163(2):207-12. PMID: 10556769
Article Published Date : Nov 01, 1999
Study Type : Animal Study
Additional Links
Substances : Gymnema Sylvestre
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
[+]

Naringin was found to be an effective antidiabetic agent which increased Insulin gene expression and insulin secretion.Dec 31, 2017

Pubmed Data : Cells Tissues Organs. 2018 ;206(3):133-143. Epub 2019 Mar 18. PMID: 30884485
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Insulin Resistance
Pharmacological Actions : Insulin-releasing
Additional Keywords : Gene Expression Regulation
[+]

Nigella sativa stimulate insulin secretion from isolated rat islets and inhibit the digestion and absorption of (CH2O)n in the gut.Aug 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2019 Aug 2. Epub 2019 Aug 2. PMID: 31375555
Article Published Date : Aug 01, 2019
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Noni fruit juice prevents ischemic neuronal damage through suppression of the development of post-ischemic glucose intolerance.Oct 01, 2010

Pubmed Data : J Nat Med. 2010 Oct;64(4):468-73. Epub 2010 Jun 24. PMID: 20574728
Article Published Date : Oct 01, 2010
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Brain Ischemia, Cerebral Ischemia
Pharmacological Actions : Insulin-releasing, Neuroprotective Agents
[+]

Phellinus linteus extracts could significantly decrease serum glucose concentration and increases insulin secretion in the islets of Langerhans.Dec 31, 2015

Pubmed Data : Int J Med Mushrooms. 2016 ;18(4):301-11. PMID: 27481296
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Phellinus Linteus
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Probiotic Lactobacillus gasseri SBT2055 improves insulin secretion in a diabetic rat model.Jan 31, 2019

Pubmed Data : J Dairy Sci. 2019 Feb ;102(2):997-1006. Epub 2018 Nov 22. PMID: 30471910
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus gasseri, Probiotics
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

Stevia contains compounds which enhance the insulin secretion of beta cells. Feb 01, 2000

Pubmed Data : Metabolism. 2000 Feb;49(2):208-14. PMID: 10690946
Article Published Date : Feb 01, 2000
Study Type : Animal Study
Additional Links
Substances : Stevia
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
[+]

The antihyperglycemic activity of B. monosperma was mediated by enhanced insulin secretion and enhanced glycogen formation in the liver.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2014 ;2014:356290. Epub 2014 Mar 31. PMID: 24860609
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Palash
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

The combination treatment with ursolic acid and rosiglitazone ameliorated HFD-induced glucose intolerance and insulin resistance.May 31, 2016

Pubmed Data : J Physiol Biochem. 2016 Jun ;72(2):345-52. Epub 2016 Apr 18. PMID: 27090933
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : High Fat Diet, Insulin Resistance
Pharmacological Actions : Insulin-releasing
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These results showed that hypoglycemic effects of MOLE might be mediated through the stimulation of insulin release leading to enhanced glucose uptake and glycogen synthesis.Jun 26, 2015

Pubmed Data : J Basic Clin Physiol Pharmacol. 2015 Jun 27. Epub 2015 Jun 27. PMID: 26124050
Article Published Date : Jun 26, 2015
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Diabetes Mellitus: Type 2, Hypoglycemia
Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents, Insulin-releasing
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
Problem Substances : Metformin
[+]

This study has provided evidence that clearly supported the traditional use of Goto Kola as a remedy for diabetes.Jan 12, 2016

Pubmed Data : J Ethnopharmacol. 2016 Jan 13. Epub 2016 Jan 13. PMID: 26775274
Article Published Date : Jan 12, 2016
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

A Portulaca oleracea L. extract promotes insulin secretion.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2018 Jun ;12(3):183-190. Epub 2018 Apr 25. PMID: 29854323
Article Published Date : May 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Purslane
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Insulin-releasing
Additional Keywords : Dose Response
[+]

A. camphorata might have anti-diabetic effects and could be a novel treatment for T2DM.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:67. Epub 2016 Mar 21. PMID: 27047382
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Antrodia camphorata
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Apoptotic, Insulin-releasing
Additional Keywords : Plant Extracts
[+]

American Ginseng Stimulates Insulin Production and Prevents Beta Cell Death. Sep 01, 2006

Pubmed Data : Evid Based Complement Alternat Med. 2006 Sep;3(3):365-72. PMID: 16951721
Article Published Date : Sep 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Ginseng (American)
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
Additional Keywords : Beta Cell Protection
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Andrographis exhibits insulin-releasing cells in vitro.Apr 01, 2008

Pubmed Data : Acta Med Indones. 2008 Apr-Jun;40(2):63-8. PMID: 18560025
Article Published Date : Apr 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Andrographis
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
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Cafestol may contribute to the preventive effects on T2D in coffee drinkers and be of therapeutic interest.Oct 22, 2015

Pubmed Data : J Nat Prod. 2015 Oct 23 ;78(10):2447-51. Epub 2015 Oct 14. PMID: 26465380
Article Published Date : Oct 22, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cafestol, Caffeic Acid, Coffee
Diseases : Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions : Insulin-releasing
Additional Keywords : Risk Reduction
[+]

Epicatechin flavanoid compound cause beta cell regeneration. - Article 2Mar 01, 1984

Pubmed Data : Diabetes. 1984 Mar;33(3):291-6. PMID: 6365662
Article Published Date : Mar 01, 1984
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
Additional Keywords : Beta Cell Regeneration
[+]

Gallic acid preserves beta cell function and exhibits insulin-secreting action. Jul 16, 2009

Pubmed Data : Phytother Res. 2009 Jul 16. PMID: 19610036
Article Published Date : Jul 16, 2009
Study Type : In Vitro Study
Additional Links
Substances : Gallic Acid
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Insulin-releasing
Additional Keywords : Beta Cell Regeneration
[+]

Lagerstroemia speciosa leaves were effective in the treatment of diabetes.Apr 30, 2013

Pubmed Data : Mol Med Rep. 2013 May ;7(5):1607-12. Epub 2013 Mar 26. PMID: 23545843
Article Published Date : Apr 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Banaba
Diseases : Diabetes Mellitus: Type 1, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Cytoprotective, Insulin-releasing, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Phenolic substances from Ocimum species enhance glucose-stimulated insulin secretion.Dec 21, 2017

Pubmed Data : J Nat Prod. 2017 Dec 22 ;80(12):3267-3275. Epub 2017 Dec 1. PMID: 29192771
Article Published Date : Dec 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : Basil
Diseases : Insulin Disorders
Pharmacological Actions : Insulin-releasing
Additional Keywords : Gene Expression Regulation
[+]

Resveratrol may positively modulate insulin secretion and response in beta cells. Feb 25, 2011

Pubmed Data : J Biol Chem. 2011 Feb 25;286(8):6049-60. Epub 2010 Dec 16. PMID: 21163946
Article Published Date : Feb 25, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Blood Sugar Problems, Insulin Resistance
Pharmacological Actions : Insulin-releasing
[+]

The aim of this review is to report on the available anti-diabetic polyphenols, medicinal plants, fruits and vegetables and their potential in the treatment of diabetes mellitus.Nov 23, 2015

Pubmed Data : Curr Pharm Des. 2015 Nov 24. Epub 2015 Nov 24. PMID: 26601968
Article Published Date : Nov 23, 2015
Study Type : Review
Additional Links
Substances : Apricot, Blackberries, Cocoa, Coffee, Eggplant, Grapes, Green Tea, Polyphenols
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Glucose Uptake Optimization, Insulin-releasing
Additional Keywords : Risk Reduction
[+]

The antidiabetic effectiveness of momordica was compared to active treatment with several oral antidiabetic drugs and proved it had comparable effects.Dec 31, 2014

Pubmed Data : Ceska Slov Farm. 2015 ;64(4):126-32. PMID: 26459126
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Bitter Melon
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin-releasing, Insulin Sensitizers
Additional Keywords : Natural Substances Versus Drugs
[+]

These results validate the traditional use of Nelumbo Nucifera leaves for the management of diabetes.Jan 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Chin Med. 2016 Feb ;36(1):71-7. PMID: 26946622
Article Published Date : Jan 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Insulin-releasing, Interleukin-1 beta downregulation
Additional Keywords : Plant Extracts
[+]

This review summarizes the antidiabetic potentials of the genus Ficus.Jan 02, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jan 3. Epub 2018 Jan 3. PMID: 29305899
Article Published Date : Jan 02, 2018
Study Type : Review
Additional Links
Substances : Fig
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents, Insulin-releasing
[+]

Viscothionin purified from mistletoe induces insulin secretion from pancreatic beta cells.Apr 23, 2019

Pubmed Data : J Ethnopharmacol. 2019 Apr 24 ;234:172-179. Epub 2019 Jan 17. PMID: 30660712
Article Published Date : Apr 23, 2019
Study Type : In Vitro Study
Additional Links
Substances : Mistletoe
Diseases : Diabetes Mellitus: Type 2, Hypoglycemia
Pharmacological Actions : Alpha-glucosidase inhibitor , Insulin-releasing
Additional Keywords : Plant Extracts

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