Photoprotective

Name	AC	CK
Frankincense	1	10
Grapefruit	1	10
Quercetin	1	10
Rosemary	1	10
Hesperidin	1	5
Lemon Balm	1	5
Achiote	2	3
Cocoa	2	3
Aloe Vera	1	2
Apigenin	1	2
Bifidobacterium Breve	1	2
Ferulic acid	1	2
Garlic	1	2
Kaempferia parviflora	1	2
Lotus	1	2
Naringenin	1	2
Patchouli	1	2
Spirulina	1	2
Vitamin E	2	2
Black Tea	1	1
Carotenoids	1	1
Coconut oil: topical	1	1
Flavonoids	1	1
Green Tea	1	1
Krameria lappacea: topical	1	1
Luteolin	1	1
Olive oil: topical	1	1
Peanut oil: topical	1	1
Polyphenols	1	1
Pycnogenol (Pine Bark)	1	1
Rose Hips	1	1
Sage	1	1
Sesame oil: topical	1	1
Silibinin	1	1
Tocopherols	1	1
Vitamin C	1	1
Vitamin D	1	1

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A combination of rosemary and grapefruit polyphenols have photoprotective and anti-ageing effects. Dec 31, 2015

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Pubmed Data : Photodermatol Photoimmunol Photomed. 2020 Feb 18. Epub 2020 Feb 18. PMID: 32072695

Article Published Date : Feb 17, 2020

Study Type : Human Study

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Substances : Carotenoids

Diseases : Erythema, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Photoprotective

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L. paracasei KW3110 suppressed blue light-induced retinal pigment epithelial cell death.Aug 08, 2018

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Pubmed Data : Nutrients. 2018 Mar 31 ;10(4). Epub 2018 Mar 31. PMID: 29614719

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Pubmed Data : J Dermatolog Treat. 2019 Mar 21:1-9. Epub 2019 Mar 21. PMID: 30897007

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Pubmed Data : Pharm Biol. 2017 Dec ;55(1):1032-1040. PMID: 28183235

Article Published Date : Nov 30, 2017

Study Type : Animal Study

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Substances : Prickly Pear Cactus

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Photoprotective

Additional Keywords : Plant Extracts

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Caffeic acid prevents UVB radiation induced photocarcinogenesis.Jul 31, 2018

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Pubmed Data : Toxicol Appl Pharmacol. 2018 Aug 1 ;352:87-96. Epub 2018 May 23. PMID: 29802912

Article Published Date : Jul 31, 2018

Study Type : Animal Study

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Substances : Caffeic Acid

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Anticarcinogenic Agents, Photoprotective

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Chrysanthemum indicum was a novel photo-protective agent from natural resources against UV irradiation.Sep 30, 2015

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Nexrutine inhibits the ultraviolet B induced cutaneous inflammatory responses in SKH-1 mouse skin.Dec 31, 2017

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Pubmed Data : Photodermatol Photoimmunol Photomed. 2018 Jan ;34(1):82-90. Epub 2017 Oct 9. PMID: 28857273

Article Published Date : Dec 31, 2017

Study Type : Animal Study

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Substances : Nexrutine (Phellodendrom)

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Anti-Inflammatory Agents, Photoprotective

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Oral administration of black ginger extract significantly prevents UVB-induced photoaging in hairless mice.Sep 30, 2014

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Pubmed Data : Photodermatol Photoimmunol Photomed. 2014 Oct ;30(5):237-45. Epub 2014 Jan 9. PMID: 24313661

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Pubmed Data : Phytother Res. 2018 Sep ;32(9):1741-1749. Epub 2018 May 10. PMID: 29748977

Sesamin has potential for use as a skin protection agent in antiphotodamage and skin care products.Sep 11, 2019

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Pubmed Data : Free Radic Biol Med. 2015 Dec ;89:690-700. Epub 2015 Nov 4. PMID: 26456052

Article Published Date : Nov 30, 2015

Study Type : Animal Study, Transgenic Animal Study

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Substances : Achiote

Diseases : Skin Cancer: Prevention, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Chemopreventive, Nrf2 activation, Photoprotective

Additional Keywords : Nutritional Sunscreen, Plant Extracts

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The dietary ingestion of Aloe sterols protected against chronic UVB damage in mouse skin.Dec 19, 2016

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Pubmed Data : Photodermatol Photoimmunol Photomed. 2016 Dec 20. Epub 2016 Dec 20. PMID: 27995657

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Pubmed Data : Biomol Ther (Seoul). 2016 Nov 1 ;24(6):616-622. PMID: 27257012

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Pubmed Data : Arch Biochem Biophys. 2019 02 15 ;662:190-200. Epub 2018 Dec 17. PMID: 30571966

Article Published Date : Jan 14, 2019

Study Type : In Vitro Study

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Substances : Hibiscus

Diseases : Aging Skin, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Antioxidants, Photoprotective

Additional Keywords : Plant Extracts

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Empetrum nigrum extract suppresses ultraviolet B-induced cell damage.Dec 31, 2012

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Pubmed Data : Int J Biol Macromol. 2020 Oct 31. Epub 2020 Oct 31. PMID: 33144254

Article Published Date : Oct 30, 2020

Study Type : In Vitro Study

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Substances : Fucoidan

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Photoprotective

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Galangin shields human keratinocytes from ultraviolet B-induced oxidative stress.Feb 28, 2015

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Pubmed Data : Biomol Ther (Seoul). 2015 Mar ;23(2):165-73. Epub 2015 Mar 1. PMID: 25767685

Article Published Date : Feb 28, 2015

Study Type : In Vitro Study

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Substances : Flavonoids

Diseases : Photooxidative Stress, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Photoprotective

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Ganoderma polysaccharides treatment may serve as a novel strategy for antiphotoaging.Dec 31, 2016

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Pubmed Data : Mol Med Rep. 2017 Jan ;15(1):111-116. Epub 2016 Dec 12. PMID: 27959406

Herbs provide protection against harmful UV radiation due to their antioxidant activity.Jul 01, 2011

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Pubmed Data : Pharmacogn Rev. 2011 Jul ;5(10):164-73. PMID: 22279374

Article Published Date : Jul 01, 2011

Study Type : Review

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Substances : Coconut oil: topical, Flavonoids, Krameria lappacea: topical, Olive oil: topical, Peanut oil: topical, Sesame oil: topical, Vitamin C, Vitamin E

Diseases : Skin Diseases: Photo-Aging, Sunburn, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Antioxidants, Photoprotective

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Hydroxytyrosol might be proposed as an encouraging candidate for the prevention of blue light-induced premature photoaging.May 31, 2019

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Pubmed Data : J Cell Physiol. 2019 Jun ;234(6):9065-9076. Epub 2018 Oct 26. PMID: 30367495

Article Published Date : May 31, 2019

Study Type : In Vitro Study

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Substances : Hydroxytyrosol

Diseases : Blue Light Toxicity

Pharmacological Actions : Photoprotective

Anti Therapeutic Actions : Blue Light (400−495 nm)

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Pubmed Data : Free Radic Biol Med. 2012 Sep 15 ;53(6):1298-307. Epub 2012 Jun 23. PMID: 22732187

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Pubmed Data : Genet Mol Res. 2005 ;4(1):94-9. Epub 2005 Mar 31. PMID: 15841440

Article Published Date : Dec 31, 2004

Study Type : In Vitro Study

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Substances : Achiote

Diseases : DNA damage, Oxidative Stress, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Antimutagenic Agents, Photoprotective

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Overlapping functions of tocopherols and carotenoids are present in protection against photooxidative stress.Jan 01, 2012

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Pubmed Data : Plant Physiol. 2012 Jan ;158(1):313-23. Epub 2011 Nov 11. PMID: 22080601

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Pubmed Data : Photochem Photobiol. 2019 Jan 12. Epub 2019 Jan 12. PMID: 30636010

Article Published Date : Jan 11, 2019

Study Type : In Vitro Study

Additional Links

Substances : Apigenin, Flavonoids, Naringenin

Diseases : Ultraviolet Radiation Induced Damage

Pharmacological Actions : Genoprotective, Photoprotective

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piceatannol and passion fruit seed extract containing high amounts of piceatannol are potential anti-photoageing cosmetic ingredients.Dec 31, 2012

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Pubmed Data : Yao Xue Xue Bao. 2012 May ;47(5):609-13. PMID: 22812004

Article Published Date : Apr 30, 2012

Study Type : In Vitro Study

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Substances : Puerarin

Diseases : DNA damage, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Photoprotective

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Pycnogenol provides photoprotection and may be used to reduce hyperpigmentation of human skin.Dec 31, 2015

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Pubmed Data : Int J Radiat Biol. 2015 May 13:1-24. Epub 2015 May 13. PMID: 25968555

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Pubmed Data : Biol Pharm Bull. 2014 ;37(10):1583-90. Epub 2014 Jul 24. PMID: 25056231

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Aging Skin, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor, Photoprotective

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These results demonstrate that walnuts can protect human epidermal keratinocytes against UVB-induced mitochondria-mediated apoptosis.Dec 31, 2013

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Pubmed Data : Skin Pharmacol Physiol. 2014 ;27(3):132-40. Epub 2014 Jan 11. PMID: 24434642

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Pubmed Data : Front Pharmacol. 2020 ;11:736. Epub 2020 May 15. PMID: 32499710

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Paeoniflorin

Diseases : Photooxidative Stress, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Photoprotective

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UVA photoprotective activity of brown macroalgae Sargassum cristafolium.Sep 26, 2019

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View the Evidence: 184 Abstracts with Photoprotective Research

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A combination of rosemary and grapefruit polyphenols have photoprotective and anti-ageing effects. Dec 31, 2015

Astaxanthin seems protective against UV-induced skin deterioration and helps maintain healthy skin in healthy people.Jun 24, 2018

Continuous administration of apple polyphenol for 12 weeks alleviated ultraviolet irradiation induced skin pigmentation.Apr 12, 2020

Cutaneous photoprotective activity of a short-term ingestion of high flavanol cocoa.Jan 19, 2019

Daily oral pomegranate consumption may lead to enhanced protection from ultraviolet photodamage.Oct 09, 2019

Daily supplementation with carotenoids protects human skin against both UVB-induced erythema and UVA-induced pigmentation.Feb 17, 2020

L. paracasei KW3110 suppressed blue light-induced retinal pigment epithelial cell death.Aug 08, 2018

Long-term prophylactic astaxanthin supplementation may inhibit age-related skin deterioration.Jun 30, 2017

Protective effects of a topical antioxidant mixture against ultraviolet-induced photodamage in human skin.Nov 30, 2008

Quercetin is able to reduce redness, itching, and inflammation of damaged skin; it may also help restore skin barrier function.Dec 31, 2015

These findings are preliminary confirmation of the anti-aging benefit to the skin of L. plantarum HY7714 as a nutricosmetic agent.Dec 27, 2015

Topical application of boswellic acids may represent a suitable treatment option for selected features of skin photoaging.Dec 31, 2009

Carvacrol mediates its protective effect through modulation of UVB-induced ROS.Oct 31, 2015

Cultured coconut extract showed a barrier-enhancing effect and anti-inflammatory properties against UVB irradiation-induced inflammation.Jul 31, 2017

Fennel is a potential botanical agent for the treatment of skin damage induced by UV irradiation.Nov 14, 2016

Fucoxanthin exerted a protective effect against UV irradiation.Aug 31, 2016

Hesperidin shielded human keratinocytes from UVB radiation-induced damage and apoptosis.Jan 14, 2016

Hesperidin treatment effectively protected HaCaT keratinocytes from these UVA radiation-induced skin injuries.Nov 30, 2016

Lemon balm extract may be considered as a candidate for oral or topical photoprotective agents against UVB-induced skin damage.Aug 03, 2016

Melon concentrate administration could be a useful strategy for photoprotection due to its antioxidant properties.Mar 30, 2018

Piperine attenuates UV-R induced cell damage in human keratinocytes.Jun 30, 2017

Piperine attenuates UV-R induced cell damage in human keratinocytes.Jun 30, 2017

Protective effect of a fucose-rich fucoidan isolated from Saccharina japonica against ultraviolet B-induced photodamage.Jun 14, 2020

Skin protective activity of silymarin and its flavonolignans.Mar 13, 2019

Strawberry-based formulations protect human dermal fibroblasts against UVA-induced damage.Jun 13, 2017

Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin.May 31, 2009

Turmeric extract and its curcuminoids provided significant protection against photooxidative damage and apoptosis retinal cells.Feb 28, 2017

Wild chrysanthemum extract prevents UVB radiation-induced acute cell death and photoagingFeb 29, 2016

Aloe polysaccharide protects skin cells from UVB irradiation.Mar 20, 2019

An aloe vera gel powder containing aloe sterols prevents skin damage induced by UVB irradiation.Oct 11, 2016

Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo.Jun 05, 2016

Bifidobacterium breve supplementation has a photoprotective effect against skin damage induced by ultraviolet irradiation in hairless mice.Nov 30, 2012

Cacao extract may offer a protective effects against photo-aging.Feb 04, 2016

Cactus cladodes extract minimizes the effects of UV irradiation on keratinocytes and hairless mice.Nov 30, 2017

Caffeic acid prevents UVB radiation induced photocarcinogenesis.Jul 31, 2018

Chrysanthemum indicum was a novel photo-protective agent from natural resources against UV irradiation.Sep 30, 2015

Cold-pressed perilla oil has therapeutic potential in terms of protecting against skin photo-aging.Feb 21, 2020

CoQ10 reduces corneal damages after UVB exposure in vivo and in vitro by preserving mitochondrial function.Oct 08, 2014

Didymin improves UV irradiation resistance in C. elegans.Dec 31, 2018

Dietary astaxanthin accumulates in the skin and appears to prevent the effects of UVA.Dec 31, 2016

Dietary immature Citrus unshiu alleviates UVB- induced photoaging.May 31, 2020

Effects of oral administration of Lonicera caerulea berries on UVB-induced damage in SKH-1 mice.Sep 30, 2013

Effects of topical application of patchouli alcohol on the UV-induced skin photoaging in mice.Oct 14, 2014

Ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation.Jul 31, 2010

Ergostatrien-3β-ol has significant beneficial antiinflammatory and antiphotoaging activities.Sep 09, 2016

Fermented blackberry by Lactobacillus plantarum can be a potential candidate for protecting skin aging against UV irradiation.Oct 10, 2019

Ferulic acid has potential against UVB-induced carcinogenesis in the swiss albino mice.Jul 31, 2015

Formulations containing naringenin may be a promising approach to protecting the skin from the deleterious effects of UVB irradiation.Dec 31, 2015

Fucoxanthin could be a novel adjuvant for preventing exacerbations associated with skin inflammation as well as protecting skin against UV radiation.Oct 09, 2018

Garlic may be effective for preventing skin photoaging accelerated by UV irradiation through the antioxidative system and MMP regulation.Dec 31, 2015

Grape stem extract reduces UVB-induced oxidative damage and hence can play a protective role in skin photo-damage.Jul 31, 2017

Hawthorn polyphenol extract inhibits UVB-induced skin photoaging.Aug 14, 2018

Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth.Jan 25, 2017

Korean red ginseng is an excellent skin whitening and anti-aging product.Apr 30, 2020

Long-term intake of the lotus seed tea showed the effect of preventing loss of skin moisture, mitigating the formation of abnormal keratinocytes.Aug 31, 2015

Low molecular-weight fucoidan can be used as a skin-protective remedy for photoaging.Aug 17, 2018

Mekabu fucoidan is an effective suppressor of inflammation in an ultraviolet B-irradiated mouse model.Sep 30, 2015

N-acetylcysteine protects against chorioretinal damage induced by photodynamic therapy. Apr 17, 2018

Neuroprotective effect of bilberry extract in a murine model of photo-stressed retina.Dec 31, 2016

Nexrutine inhibits the ultraviolet B induced cutaneous inflammatory responses in SKH-1 mouse skin.Dec 31, 2017

Oral administration of black ginger extract significantly prevents UVB-induced photoaging in hairless mice.Sep 30, 2014

Oral Aloe vera gel powder has the ability to prevent the skin photoaging.Apr 03, 2016

Oral supplementation of L-glutathione prevents UVB-induced melanogenesis and oxidative stress.Jun 25, 2019

Paeonol a promising botanical in protecting skin from UVB-induced photoaging.Aug 31, 2018

Patchouli oil was capable of maintaining skin structural integrity caused by UV irradiation and it was useful in preventing photoaging.Jun 10, 2014

Peach flower extract is an effective and natural product for prevention and treatment of skin aging.Jan 31, 2018

Perilla frutescens leaves extract ameliorates ultraviolet radiation-induced extracellular matrix damage.Jan 03, 2017

Photoprotective and immunoregulatory capacity of ginsenoside Rg1 in chronic ultraviolet B-irradiated BALB/c mouse skin.Sep 30, 2013

Photoprotective effect of dietary galacto-oligosaccharide (GOS) in hairless mice via regulation of the MAPK signalling pathway.Apr 05, 2020

Pomegranate juice concentrated powder has favourable protective effects against UVB-induced photoaging through anti-apoptotic effects.Jul 31, 2017

Potential photoprotective effect of dietary corn silk extract on ultraviolet B-induced skin damage.Jul 15, 2019

Pretreatment with fucoxanthin may protect against UVB radiation-induced corneal disorders.Jan 06, 2016

Photoprotective

View the Evidence:
184 Abstracts with Photoprotective Research