Prophylactic Agents

Name	AC	CK
Vitamin C	2	30
Black Tea	1	20
Catechin	1	20
Green Tea	1	20
Melatonin	2	20
Elderberry	1	10
Gotu Kola	1	10
Pine Bark Extract	1	10
Pycnogenol (Pine Bark)	1	10
EGCG (Epigallocatechin gallate)	3	4
Polyphenols	2	3
Pomegranate	2	3
Quercetin	2	3
Bifidobacterium Longum	1	2
Black Raspberry	1	2
Chokeberry	1	2
Cinnamon	1	2
Cumin	1	2
Ginkgo biloba	1	2
Hops	1	2
Mustard Seeds	1	2
Probiotics	1	2
Red Clover	1	2
Reishi Mushroom	1	2
Rhubarb	1	2
Spirulina	1	2
Thyme	1	2
Apples	1	1
Blueberry	1	1
Curcumin	1	1
Fig	1	1
Resveratrol	1	1
Rutin	1	1
Toona sinensis	1	1

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Gargling with tea and its ingredients may have a preventative effect for influenza infection. Dec 31, 2015

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Pubmed Data : Adv Pharm Bull. 2016 Jun ;6(2):243-50. Epub 2016 Jun 30. PMID: 27478787

Article Published Date : May 31, 2016

Study Type : Meta Analysis

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Substances : Vitamin C

Diseases : Atrial Fibrillation, Cardiac Surgery

Pharmacological Actions : Prophylactic Agents

Additional Keywords : Risk Reduction

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A 14-strain probiotic mixture could be an effective and beneficial supplement to improve migraine headache in both chronic and episodic migraineurs.Jan 07, 2019

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Pubmed Data : Cephalalgia. 2019 Jan 8:333102418820102. Epub 2019 Jan 8. PMID: 30621517

Elderberry supplementation reduces cold duration and symptoms in air-travellers.Dec 31, 2015

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Pubmed Data : Pain Ther. 2020 Dec ;9(2):741-750. Epub 2020 Oct 16. PMID: 33067764

Article Published Date : Nov 30, 2020

Study Type : Human Study

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Substances : Melatonin

Diseases : Headache

Pharmacological Actions : Prophylactic Agents

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Melatonin was superior to amitriptyline in the percentage of patients with a greater than 50% reduction in migraine frequency.May 09, 2016

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Pubmed Data : Pediatr Res. 2015 Jun ;77(6):823-8. Epub 2015 Mar 11. PMID: 25760553

Article Published Date : May 31, 2015

Study Type : Human Study

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Substances : Probiotics

Diseases : Attention Deficit Disorder with Hyperactivity

Pharmacological Actions : Gastrointestinal Agents, Prophylactic Agents

Additional Keywords : Risk Reduction

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Probiotic supplementation has a positive effect on the prevention and treatment of infantile eczema.Apr 30, 2015

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Pubmed Data : Nutrition. 2017 Jun ;38:74-79. Epub 2017 Feb 2. PMID: 28526386

Article Published Date : May 31, 2017

Study Type : Human Study

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Substances : Folic Acid , Vitamin B-6

Diseases : Headache: Migraine

Pharmacological Actions : Prophylactic Agents

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Supplementation with a probiotic/vitamin C combination may be beneficial in the prevention and management of upper respiratory tract infections.Feb 28, 2015

Pubmed Data : Nutr Neurosci. 2019 Jun 26:1-10. Epub 2019 Jun 26. PMID: 31241007

Article Published Date : Jun 25, 2019

Study Type : Human Study

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Substances : Coenzyme Q10, Curcumin

Diseases : Headache: Migraine

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Prophylactic Agents

Additional Keywords : Natural Substance Synergy

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Thiamine therapy could be a protective factor for dementia development in patients with alcohol use disorder.May 20, 2018

Article Published Date : Feb 28, 2017

Study Type : Human Study

Additional Links

Substances : Coenzyme Q10

Diseases : Headache: Migraine

Pharmacological Actions : Analgesics, Prophylactic Agents

Additional Keywords : Analgesics, Coenzyme Q10, Headache: Migraine, Prophylactic Agents

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Use of coconut oil helps in dermal maturity and better neurodevelopmental outcome of preterm newborns.Jun 28, 2019

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Pubmed Data : J Trop Pediatr. 2019 Jun 29. Epub 2019 Jun 29. PMID: 31257430

Article Published Date : Jun 28, 2019

Study Type : Human Study

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Substances : Coconut Oil

Diseases : Premature Birth, Sepsis

Pharmacological Actions : Neuroprotective Agents, Prophylactic Agents

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Pubmed Data : Iran J Med Sci. 2016 May ;41(3 Suppl):S71. PMID: 27840537

Article Published Date : Apr 30, 2016

Study Type : Animal Study

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Substances : Ginger

Diseases : Alcohol Toxicity

Pharmacological Actions : Prophylactic Agents

Additional Keywords : Plant Extracts

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Ginkgo biloba and red clover in combination was more effective as protective agents compared to each one of them alone.Jul 31, 2016

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Pubmed Data : Food Chem Toxicol. 2016 Aug ;94:112-27. Epub 2016 May 24. PMID: 27234133

Article Published Date : Jul 31, 2016

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Pubmed Data : Kidney Int. 2019 Nov 2. Epub 2019 Nov 2. PMID: 31866113

Article Published Date : Nov 01, 2019

Study Type : Animal Study

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Substances : Magnesium

Diseases : Vascular Calcification

Pharmacological Actions : Prophylactic Agents

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Mango fruit powder intake exerts protective effects in the initial steps of insulin resistance and hepatic lipid accumulation.Dec 31, 2016

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Pubmed Data : Cell Physiol Biochem. 2017 ;42(2):564-578. Epub 2017 Jun 5. PMID: 28578347

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Prophylactic and therapeutic effects of different doses of vitamin C on high-fat-diet-induced non-alcoholic fatty liver disease.Oct 31, 2020

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Spirulina extract was found to act at an early stage of infection to reduce virus yields in cells and improve survival in influenza-infected mice.Dec 31, 2015

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Pubmed Data : Sci Rep. 2016 ;6:24253. Epub 2016 Apr 12. PMID: 27067133

Article Published Date : Dec 31, 2015

Study Type : Animal Study

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Substances : Spirulina

Diseases : Influenza A

Pharmacological Actions : Antiviral Agents, Prophylactic Agents

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Supplementation of β-cryptoxanthin would be beneficial for the maintenance of joint health and as prophylaxis against osteoarthritis.Dec 31, 2016

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Pubmed Data : Iran J Immunol. 2006 Dec ;3(4):164-8. PMID: 18685176

Article Published Date : Nov 30, 2006

Study Type : Animal Study

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Substances : Zataria multiflora

Pharmacological Actions : Immunostimulatory, Prophylactic Agents

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Pubmed Data : Glob Adv Health Med. 2020 ;9:2164956120934768. Epub 2020 Jul 20. PMID: 32733775

Article Published Date : Dec 31, 2019

Study Type : Review

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Substances : Vitamin C, Vitamin C: Intravenous

Diseases : Coronavirus Infection, Respiratory Distress Syndrome, Sepsis

Pharmacological Actions : Prophylactic Agents

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Berberine could be used as a potential adjuvant to prevent dyslipidemia and obesity caused by the use of second-generation antipsychotic medication.Nov 08, 2016

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Pubmed Data : Int J Mol Sci. 2016 Nov 9 ;17(11). Epub 2016 Aug 9. PMID: 27834848

Article Published Date : Nov 08, 2016

Study Type : In Vitro Study

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Substances : Berberine

Diseases : Dyslipidemias, Obesity

Pharmacological Actions : Prophylactic Agents

Problem Substances : Antipsychotic Drugs, Olanzapine

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Blueberry juice and blueberry proanthocyanidins shows preventive potential against infection.Jun 13, 2016

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Pubmed Data : Food Environ Virol. 2016 Jun 14. Epub 2016 Jun 14. PMID: 27299641

Pubmed Data : Eur J Sport Sci. 2018 Mar 13:1-15. Epub 2018 Mar 13. PMID: 29529987

Article Published Date : Mar 12, 2018

Study Type : Review

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Substances : Beet, Spinach

Diseases : Cardiovascular Diseases, Hypertension

Therapeutic Actions : Exercise

Pharmacological Actions : Antihypertensive Agents, Cardioprotective, Prophylactic Agents

Additional Keywords : Dietary Nitrate Consumption

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Echinacea purpurea is shown to be safe and effective in the prevention of the common cold.Dec 31, 2015

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Pubmed Data : Holist Nurs Pract. 2016 Jan-Feb;30(1):54-7. PMID: 26633727

Article Published Date : Dec 31, 2015

Study Type : Review

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Substances : Echinacea

Diseases : Common Cold, Upper Respiratory Infections

Pharmacological Actions : Prophylactic Agents

Additional Keywords : Phytotherapy, Plant Extracts

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EGCG may prevent Zika virus infections.Jun 22, 2016

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Pubmed Data : Virology. 2016 Jun 23 ;496:215-218. Epub 2016 Jun 23. PMID: 27344138

Article Published Date : Jun 22, 2016

Study Type : In Vitro Study

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Substances : EGCG (Epigallocatechin gallate)

Diseases : Zika Virus

Pharmacological Actions : Antiviral Agents, Prophylactic Agents

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Elder fruit may increase lipid raft integrity and inhibit release of infectious progeny virion particles from influenza infected cells.Dec 31, 2016

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Pubmed Data : J Infect Chemother. 2014 Nov ;20(11):666-71. Epub 2014 Aug 30. PMID: 25182867

Article Published Date : Oct 31, 2014

Study Type : Review

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Substances : Lactoferrin

Diseases : Common Cold, Gastroenteritis

Pharmacological Actions : Antiviral Agents, Immunomodulatory, Prophylactic Agents

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Melatonin was as effective as amitriptyline, causes fewer adverse effects, and may have a surprising added benefit.Apr 30, 2017

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Pubmed Data : J Fam Pract. 2017 May ;66(5):320-322. PMID: 28459893

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Prevention of infections of the upper respiratory tract.Jul 31, 2018

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Pubmed Data : Laryngorhinootologie. 2018 Aug ;97(8):529-536. Epub 2018 Aug 6. PMID: 30081415

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Pubmed Data : J Biomed Sci. 2019 Jan 9 ;26(1):5. Epub 2019 Jan 9. PMID: 30621719

Article Published Date : Jan 08, 2019

Study Type : Review

Additional Links

Substances : Rosemary

Diseases : Cancers: All, Inflammation, Kidney Damage: Chemically-Induced

Pharmacological Actions : Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants, Antiviral Agents, Neuroprotective Agents, Prophylactic Agents, Renoprotective

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Lead

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Supplementation with vitamin C appears to be able to both prevent and treat respiratory and systemic infections.Nov 02, 2017

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Pubmed Data : Nutrients. 2016 ;8(5). Epub 2016 May 9. PMID: 27171110

Article Published Date : Dec 31, 2015

Study Type : Review

Additional Links

Substances : Curcumin, EGCG (Epigallocatechin gallate), Polyphenols, Quercetin, Resveratrol, Rutin

Diseases : Asbestos Toxicity, Mesothelioma

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antiproliferative , Apoptotic, Prophylactic Agents

Additional Keywords : Dose Response

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There is growing evidence that acupuncture is just as effective and has fewer side effects than many of the standard pharmaceutical agents.Dec 23, 2019

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Pubmed Data : Headache. 2019 Dec 24. Epub 2019 Dec 24. PMID: 31872864

Article Published Date : Dec 23, 2019

Study Type : Review

Additional Links

Diseases : Headache: Migraine

Therapeutic Actions : Acupuncture

Pharmacological Actions : Prophylactic Agents

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These results suggest that ginsenoside Rg3 may be a potential agent in reducing and preventing obesity.Dec 31, 2016

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Pubmed Data : Front Pharmacol. 2017 ;8:113. Epub 2017 Mar 8. PMID: 28337143

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Pubmed Data : Nutrients. 2017 Mar 29 ;9(4). Epub 2017 Mar 29. PMID: 28353648

Article Published Date : Mar 28, 2017

Study Type : Review

Additional Links

Substances : Vitamin C

Diseases : Common Cold, Pneumonia, Tetanus

Pharmacological Actions : Prophylactic Agents

Additional Keywords : Dose Response

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Zinc supplementation may be of potential benefit for prophylaxis and treatment of COVID-19.May 24, 2020

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Pubmed Data : Med Hypotheses. 2020 May 25 ;144:109848. Epub 2020 May 25. PMID: 32512490

Article Published Date : May 24, 2020

Study Type : In Vitro Study

Additional Links

Substances : Zinc

Diseases : Coronavirus Infection

Pharmacological Actions : Antiviral Agents, Prophylactic Agents

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View the Evidence: 177 Abstracts with Prophylactic Agents Research

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Gargling with tea and its ingredients may have a preventative effect for influenza infection. Dec 31, 2015

Promising preventive and therapeutic effects of TaibUVID nutritional supplements for COVID-19.Dec 31, 2019

Therapeutic vitamin C supplementation may be reasonable for pneumonia patients who have low vitamin C plasma levels.Aug 07, 2013

Vitamin C is effective as prophylaxis for the prevention of postoperative atrial fibrillation.May 31, 2016

A 14-strain probiotic mixture could be an effective and beneficial supplement to improve migraine headache in both chronic and episodic migraineurs.Jan 07, 2019

Beetroot juice during periods of psychological stress protects against cold symptoms.Mar 31, 2019

Coenzyme Q10 and L-carnitine supplements have beneficial effects on serum levels of lactate and migraine symptoms.Jan 05, 2019

Combined antioxidant therapy with N-acetylcysteine reduces headaches and migraines in adult migraineurs.Apr 18, 2020

Continuous daily ingestion of 1073R-1-yogurt may help prevent infection with influenza A virus subtype H3N2 in elderly subjects with weakened immunity.May 15, 2019

Current evidence indicates that lactoferrin could significantly reduce the incidence of necrotizing enterocolitis and late-onset sepsis.Jul 31, 2018

D-mannose powder had significantly reduced the risk of recurrent urinary tract infection.Jan 31, 2014

Daily supplementation of children's diet with yogurt containing probiotics significantly reduced days of fever and improved social and school functioning.May 31, 2015

Drinking either black or green tea was associated with a dose-dependent reduction in tuberculosis risk.May 24, 2017

Elderberry supplementation reduces cold duration and symptoms in air-travellers.Dec 31, 2015

Episodic primary migraine headache: prophylaxis with Pycnogenol precents attacks and controls oxidative stress.Oct 24, 2019

Flavonoids contained in fruits and vegetables, especially flavanones, might reduce the risk of non-allergic rhinitis.Jan 29, 2020

Green tea gargling could be used in the prevention of influenza infection.Jan 31, 2017

High-dose riboflavin is a safe, well tolerated, cost-effective method of prophylaxis for children with migraine.Jan 31, 2018

High-dose vitamin D is suitable for the prevention of seasonal influenza as evidenced by rapid relief from symptoms and a decrease in viral loads.Jan 07, 2018

Intake of vitamin C, vitamin E, selenium, zinc and polyunsaturated fatty acids and upper respiratory tract infection.Dec 31, 2016

Melatonin could be used in migraine prophylaxis treatments. Dec 31, 2017

Melatonin is an effective and safe alternative for the treatment of chronic tension-type headache.Nov 30, 2020

Melatonin was superior to amitriptyline in the percentage of patients with a greater than 50% reduction in migraine frequency.May 09, 2016

Moderate fish and long chain omega-3 PUFA intake was associated with lower odds of depression.Dec 17, 2018

Perinatal maternal probiotic supplementation with a combination of LGG, Bb-12 and La-5 reduced the proportion of Th22 cells in 3-month-old children.Mar 26, 2017

Physical training produces a decrease in erythrocyte concentrations of cadmium and lead.Jul 28, 2019

Pinus radiata bark extract and vitamin C led to a 50% reduction of frequency and severity of headaches.Feb 28, 2013

Probiotic supplementation early in life may reduce the risk of neuropsychiatric disorder development later in childhood.May 31, 2015

Probiotic supplementation has a positive effect on the prevention and treatment of infantile eczema.Apr 30, 2015

Probiotics could be used to prevent respiratory infections in nursing homes.Dec 31, 2017

Prophylactic administration of conventional form of silymarin tablets could significantly reduce the severity of radiotherapy induced mucositis.Aug 22, 2016

Proprietary supplement containing feverfew, coenzyme Q10 and magnesium assessed could be beneficial and safe for the prevention of migraine.Aug 29, 2017

Pycnogenol and Centella Asiatica reduce the progression of arterial plaques and the progression to clinical stages.Oct 26, 2015

Regular leisure-time exercise of any intensity provides protection against future depressionOct 02, 2017

Supplementation of folic acid with pyridoxine could decrease the characteristics of migraine attacks including headache severity and attack frequency.May 31, 2017

Supplementation with a probiotic/vitamin C combination may be beneficial in the prevention and management of upper respiratory tract infections.Feb 28, 2015

Supplementation with multivitamins and vitamin A and incidence of malaria among HIV-infected Tanzanian women.Nov 30, 2014

The intake of lactoferrin attenuates infectious diseases, including summer colds.Feb 25, 2020

The results from this controlled prospective study indicate that S. boulardii is effective for the prevention of clostridium difficile infection.Jul 31, 2018

These findings indicate that combination therapy of ω-3 fatty acids and nano-curcumin can be considered as a promising new approach in migraine prevention.Dec 31, 2018

These findings suggest a possible synergistic effect of nano-curcumin and coenzyme Q10 on clinical features of migraine.Jun 25, 2019

Thiamine therapy could be a protective factor for dementia development in patients with alcohol use disorder.May 20, 2018

This fixed-dose Tanacetum parthenium preparation improved headache frequency and pain intensity in children affected by tension-type headache.Mar 11, 2019

This pilot study shows promising results, in terms of headache frequency reduction and daily quality of life improvement.Mar 07, 2016

This study suggests that CoQ10 might reduce the frequency of headaches.Feb 28, 2017

Use of coconut oil helps in dermal maturity and better neurodevelopmental outcome of preterm newborns.Jun 28, 2019

Vitamin C is effective in preventing complex regional pain syndrome type I development after subacromial shoulder surgery.Sep 19, 2019

Vitamin C supplementation reduces the odds of developing a common cold in Republic of Korea Army recruits.Mar 04, 2020

Yoga could be an adjuvant to medical therapy that improves headache frequency, intensity, impact, and disability.May 05, 2020

Nobiletin appears to be a promising novel prophylactic seed drug or functional food for Alzheimer's disease.Dec 31, 2017

A case report of using Hawaiian baby woodrose to successfully alleviate symptoms of cluster headache and the accompanying mental health problems.May 06, 2020

Prophylactic effect of resveratrol and piperine on pristane-induced murine model of lupus-like disease.May 31, 2020

Adlay seed extracts exhibit a prophylactic effect on diet-induced metabolic dysfunction and nonalcoholic fatty liver disease.Dec 31, 2019

Aloe vera gel could be used to improve the symptoms of ulcerative colitis.Jun 30, 2020

An extract of the seeds of black mustard showed chemosuppressive activity against Plasmodium berghei infection in mice.Dec 31, 2014

Ascorbic acid serve as a prophylactic agent against renal damage in patients receiving sevoflurane anesthesia.Sep 30, 2017

Ascorbic acid treatment during pregnancy can prevent lead-induced impairments in the cerebellar development in rats.Apr 25, 2018

Astaxanthin had an anti-depressant effect on diabetic mice.Dec 21, 2016

Baicalein could be used as a cytoprotective and anti-ulcerogenic agent in gastric ulcers.Oct 21, 2016

Bifidobacterium longum as a probiotic may function as a prophylactic agent in the management of influenza.Dec 31, 2014

Black chokeberry has protective effects against the development of Alzheimer's disease.Jan 31, 2018

Black raspberry vinegar could be an effective natural alternative for the prevention of postmenopausal osteoporosis.Dec 31, 2015

Cannabidiol may be a safe and useful therapeutic agent for treating Osteoarthritis joint neuropathic pain.Aug 31, 2017

Cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models.Dec 31, 2010

Comparative hepatoprotective effect of Nigella sativa pre- and post-treatment.Dec 31, 2018

Crocetin could be used as a preventative measure against myopia progression.Jan 08, 2020

Curcumin might be a potential agent in post-operative cognitive dysfunction prophylaxis and treatment.Feb 20, 2017

Diosgenin rich food can be recommended to diabetic subjects as dietary management to postpone the occurrence of sugar cataract.Dec 31, 2016

Ethanolic extract of black chokeberry fruits not only has a potential value as a prophylactic agent but also may function as a nutritional supplement in the management of arterial hypertension.Dec 31, 2012

Ginger extract improved antioxidant enzymes activity and reduced tHcy and MDA levels.Apr 30, 2016

Ginkgo biloba and red clover in combination was more effective as protective agents compared to each one of them alone.Jul 31, 2016

Ginsenoside-Rg1 inhibits cell apoptosis induced by beta amyloid.Jun 30, 2008

Prophylactic Agents

View the Evidence:
177 Abstracts with Prophylactic Agents Research