Vascular Endothelial Growth Factor Inhibitors

Name	AC	CK
Curcumin	7	13
Bilberry	2	12
EGCG (Epigallocatechin gallate)	5	12
Cannabinoids	1	10
Delta-tetrahydrocannabinol (THC)	1	10
Polyphenols	3	8
Apple Polyphenols	1	5
Black Raspberry	1	5
Apigenin	3	4
Huaier (Trametes robiniophila murr)	2	3
Thymoquinone	2	3
Achiote	1	2
Anthocyanins	1	2
Ashwagandha	1	2
Bamboo	1	2
Betaine	1	2
Black Pepper	1	2
Boswellia	1	2
Camel Milk	1	2
Catechin	1	2
Chlorella (Algae)	1	2
Fruit Peel	1	2
Garcinia dulcis	1	2
Garcinia indica	1	2
Genistein	1	2
Ginger	1	2
Gingerol	1	2
Hesperidin	1	2
Lion's Mane (Hericium Erinaceus)	1	2
Long Pepper	1	2
Lycopene	1	2
Melatonin	2	2
Nobiletin	1	2
Sophora Flavescens	1	2
Spirulina	1	2
Tetrahydrocurcumin	1	2
Theaflavins	2	2
Thymol	1	2
Tomato	1	2
Triphala	1	2
Whey	1	2
Black Tea	1	1
Blueberry	1	1
Caffeic acid phenethyl ester	1	1
Cannabidiol	1	1
Cinnamon	1	1
Ginseng (Korean)	1	1
Guggul	1	1
Holy Basil	1	1
Luteolin	1	1
Pomegranate Peel	1	1
Prunella vulgaris.	1	1
Quercetin	1	1
Resveratrol	1	1
Schisandra	1	1

[+]

Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

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Pubmed Data : Drug Des Devel Ther. 2016 ;10:2239-53. Epub 2016 Jul 11. PMID: 27468227

Article Published Date : Dec 31, 2015

Study Type : Animal Study

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Substances : Thymoquinone

Diseases : Colorectal Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemoprotective Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor Inhibitors, Wnt/β-catenin signaling pathway modulation

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Gene Expression Regulation

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Planta Med. 2014 Dec ;80(18):1678-84. Epub 2014 Oct 15. PMID: 25317773

Article Published Date : Nov 30, 2014

Study Type : Animal Study

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Substances : Bamboo

Diseases : Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

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Betaine may potentially be used to delay the onset of complications associated with diabetic retinopathy via inhibition of retinal neovascularization in patients with diabetes.Jul 31, 2015

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Pubmed Data : Oncotarget. 2015 Jun 8. Epub 2015 Jun 8. PMID: 26116834

Article Published Date : Jun 07, 2015

Study Type : Animal Study, In Vitro Study

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Substances : Curcumin

Diseases : Leukemia: Chronic myelogenous leukemia (CML)

Pharmacological Actions : Antiproliferative , Apoptotic, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Exosomes

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Delphinidin is a promising compound to prevent pathologies associated with generation of vascular network in tumorigenesis.Dec 31, 2014

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Pubmed Data : Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID: 26919952

Article Published Date : Jan 31, 2016

Study Type : Animal Study

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Substances : Ginsenosides

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Natural Substance/Drug Synergy

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Essential oil of Pinus koraiensis leaves has anti-diabetic potential.Dec 31, 2012

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Pubmed Data : Turk J Med Sci. 2018 Feb 23 ;48(1):178-186. Epub 2018 Feb 23. PMID: 29479981

Article Published Date : Feb 22, 2018

Study Type : Animal Study

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Substances : Nigella sativa (aka Black Seed)

Diseases : Liver Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

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Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma.Dec 31, 2015

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Pubmed Data : Sci Rep. 2016 ;6:21731. Epub 2016 Feb 25. PMID: 26911838

Article Published Date : Dec 31, 2015

Study Type : Animal Study

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Substances : Apigenin

Diseases : Cancer Metastasis, Melanoma

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, STAT3 Inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer.Jul 22, 2009

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Pubmed Data : BMC Cancer. 2009 Jul 23 ;9:250. Epub 2009 Jul 23. PMID: 19624862

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Pubmed Data : Am J Chin Med. 2010;38(6):1115-30. PMID: 21061465

Article Published Date : Jan 01, 2010

Study Type : Animal Study

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Substances : Sophora Flavescens

Diseases : Breast Cancer, Breast Cancer: Metastatic, Cancer Metastasis

Pharmacological Actions : Anti-Angiogenic, Anti-Proliferative, Vascular Endothelial Growth Factor Inhibitors

[+]

Mechanism and therapeutic effects of Saccharomyces boulardii on experimental colitis.Nov 30, 2018

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Pubmed Data : J Natl Cancer Inst. 2006 Jun 21 ;98(12):846-55. PMID: 16788158

Article Published Date : Jun 20, 2006

Study Type : Animal Study

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Substances : Silibinin

Diseases : Inflammation, Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cyclooxygenase 2 Inhibitors, Vascular Endothelial Growth Factor Inhibitors

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Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma.Oct 03, 2017

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Pubmed Data : Tumour Biol. 2016 Jan 5. Epub 2016 Jan 5. PMID: 26733173

Article Published Date : Jan 04, 2016

Study Type : Animal Study

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Substances : EGCG (Epigallocatechin gallate)

Diseases : Breast Cancer, Lung Cancer

Pharmacological Actions : Antiproliferative , Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Natural Substance/Drug Synergy

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The anti-neoplastic activity of nobiletin was due to its ability to inhibit angiogenesisMay 31, 2015

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Pubmed Data : Int J Oncol. 2015 Jun ;46(6):2629-38. Epub 2015 Apr 1. PMID: 25845666

Article Published Date : May 31, 2015

Study Type : Animal Study

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Substances : Nobiletin

Diseases : Ovarian Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Hypoxia-inducible factor-1 (HIF-1) inhibitor, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor Inhibitors

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The aqueous extract of B. monosperma flowers is not only hepatoprotective but also antitumorigenic.Feb 28, 2011

Pubmed Data : Nutrition. 2015 Apr ;31(4):560-9. Epub 2014 Sep 6. PMID: 25770318

Article Published Date : Mar 31, 2015

Study Type : Animal Study, In Vitro Study

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Substances : Chlorella (Algae)

Diseases : Breast Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Vascular Endothelial Growth Factor Inhibitors

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Pubmed Data : Mol Vis. 2016 ;22:599-609. Epub 2016 Jun 9. PMID: 27293376

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Pubmed Data : BMC Complement Altern Med. 2014 ;14:419. Epub 2014 Oct 27. PMID: 25345853

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

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Substances : Holy Basil

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, PI3K/Akt/signaling suppression, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

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Antiangiogenic effect of capecitabine combined with ginsenoside Rg3 on breast cancer in mice.Sep 30, 2008

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Pubmed Data : Cancer Biother Radiopharm. 2008 Oct ;23(5):647-53. PMID: 18999937

Article Published Date : Sep 30, 2008

Study Type : In Vitro Study

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Substances : Ginsenosides

Diseases : Breast Cancer

Pharmacological Actions : Anti-Angiogenic, Chemotherapeutic, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Natural Substance/Drug Synergy

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Antiangiogenic phytochemicals and medicinal herbs may have value in the treatment of endometriosis.Jan 01, 2011

Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:3017108. Epub 2015 Nov 30. PMID: 26697130

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

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Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Synergy with Tamoxifen

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Cannabidiol exerts a potent anti-angiogenic effect by widely affecting several pathways involved in this process.Oct 31, 2012

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Pubmed Data : Biomed Pharmacother. 2018 Sep 11 ;108:65-75. Epub 2018 Sep 11. PMID: 30216802

Article Published Date : Sep 10, 2018

Study Type : In Vitro Study

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Substances : Benzyl isothiocyanate

Diseases : Liver Cancer

Pharmacological Actions : Anti-metastatic, Chemopreventive, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Chlorogenic acid can regulate theapoptosis of non-small lung cancer through Notch pathway.Aug 19, 2017

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Pubmed Data : Zhongguo Fei Ai Za Zhi. 2017 Aug 20 ;20(8):555-561. PMID: 28855037

Article Published Date : Aug 19, 2017

Study Type : In Vitro Study

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Substances : Chlorogenic Acid

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors

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Chlorogenic acid may act as a chemosensitizing agent leading to cancer growth suppression.Dec 31, 2017

Pubmed Data : Oncol Rep. 2017 Nov ;38(5):2927-2934. Epub 2017 Sep 13. PMID: 28901502

Article Published Date : Oct 31, 2017

Study Type : In Vitro Study

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Substances : Psychedelics:All

Diseases : Ovarian Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Harmine was also able to inhibit tumor cell proliferation, invasion, and migration in vitro.Dec 31, 2010

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Pubmed Data : J Environ Pathol Toxicol Oncol. 2011 ;30(2):123-37. PMID: 21967457

Article Published Date : Dec 31, 2010

Study Type : In Vitro Study

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Substances : Syrian rue

Diseases : Cancer Metastasis, Lung Cancer, Malignant Melanoma

Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Huaier is a potent anti-tumor and immunomodulatory drug, which could inhibit the infiltration of M2-macrophages in breast cancer microenvironment.Dec 31, 2015

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Pubmed Data : Sci Rep. 2016 ;6:20049. Epub 2016 Feb 1. PMID: 26831282

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

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Substances : Huaier (Trametes robiniophila murr)

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Dose Response

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In this mini-review, selected flavonoids which are a group of plant polyphenols that are able to regulate angiogenesis in vitro and in vivo systems are discussed.Dec 31, 2014

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Pubmed Data : Mini Rev Med Chem. 2015 ;15(6):479-89. PMID: 25873069

Article Published Date : Dec 31, 2014

Study Type : Review

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Substances : Apigenin, EGCG (Epigallocatechin gallate), Luteolin, Quercetin

Diseases : Cancers: All

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

[+]

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Pubmed Data : Phytother Res. 2016 Jun ;30(6):963-70. Epub 2016 Mar 1. PMID: 26929026

Article Published Date : May 31, 2016

Study Type : In Vitro Study

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Substances : Palmitoylethanolamide

Diseases : Colon Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Vascular Endothelial Growth Factor Inhibitors

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Parthenolide is a promising natural product for inhibiting and treating nicotine-associated lung cancer. Oct 31, 2018

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Pubmed Data : Biomed Pharmacother. 2018 Nov ;107:1488-1495. Epub 2018 Sep 4. PMID: 30257366

Article Published Date : Oct 31, 2018

Study Type : In Vitro Study

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Substances : Parthenolide

Diseases : Lung Cancer, Nicotine/Tobacco Toxicity

Pharmacological Actions : Apoptotic, Tumor Suppressor Protein p53 Upregulation, Vascular Endothelial Growth Factor Inhibitors

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Pubmed Data : Am J Pathol. 2010 Jul;177(1):481-92. Epub 2010 May 14. PMID: 20472894

Article Published Date : Jul 01, 2010

Study Type : In Vitro Study

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Substances : Resveratrol

Pharmacological Actions : Anti-Angiogenic, Antiproliferative , Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Stilbenes

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Rg3 enhanced the radiosensitivity of human oesophageal carcinoma cell lines cultured under hypoxic conditions.May 31, 2014

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Pubmed Data : J Int Med Res. 2014 Jun ;42(3):628-40. Epub 2014 Apr 1. PMID: 24691458

Article Published Date : May 31, 2014

Study Type : In Vitro Study

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Substances : Ginsenosides

Diseases : Esophageal Cancer

Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Radiosensitizer, Vascular Endothelial Growth Factor Inhibitors

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Schizandrin B has potent anti-tumor activity and may be a promising traditional Chinese medicine for human lung carcinoma.Dec 31, 2014

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Pubmed Data : Mar Drugs. 2017 Jun 20 ;15(6). Epub 2017 Jun 20. PMID: 28632184

Article Published Date : Jun 19, 2017

Study Type : In Vitro Study

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Substances : Fucoidan

Diseases : Osteosarcoma

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Bone Regeneration

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Cancer Res. 2008 Jun ;6(6):1059-70. PMID: 18567808

Article Published Date : May 31, 2008

Study Type : In Vitro Study

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Substances : Thymoquinone

Diseases : Acute Myeloid Leukemia, Cancers: All

Pharmacological Actions : Antiproliferative , Apoptotic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Doxorubicin

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Ursolic acid exerted chemosensitizing effects in colon cancer cells.Aug 31, 2016

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Pubmed Data : J Zhejiang Univ Sci B. 2016 Sep ;17(9):672-82. PMID: 27604859

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Pubmed Data : Pharmacogn Mag. 2018 Jan ;13(Suppl 4):S731-S736. Epub 2018 Jan 31. PMID: 29491625

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

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Substances : Zerumbone

Diseases : Liver Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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View the Evidence: 174 Abstracts with Vascular Endothelial Growth Factor Inhibitors Research

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Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patients with acute leukemia.Dec 31, 2013

Intake of bilberries has an ameliorating effect on some markers of gingival inflammation reducing gingivitis to a similar extent compared to standard of care.Dec 31, 2014

Powdered Nigella sativa has potent beneficial effects in improving thyroid status and anthropometric variables.Nov 15, 2016

Vitamin D Decreases Serum VEGF Correlating with Clinical Improvement in Vitamin D-Deficient Women with polycystic ovary syndrome.Mar 27, 2017

A Black Raspberry extract could prevent the initiation, promotion, and progression of carcinogenesis in the digestive tract and esophagus.Oct 27, 2014

Melatonin has anti-angiogenic effects at different steps of the angiogenic process in SH-SY5Y neuroblastoma cells.Feb 13, 2017

VEGF is a key molecular target for specific polyphenols found in tea, apples and cocoa which potently inhibit VEGF signalling and angiogenesis at physiological concentrations.Feb 28, 2015

5-FU and thymoquinone combination therapy resulted in a more significant reduction on AOM-induced colorectal tumors.Dec 31, 2015

A ashwagandha water extract suppressed the tumor growth of glioma cells.Jul 25, 2015

A Huaier polysaccharide restrains hepatocellular carcinoma growth and metastasis.Mar 31, 2015

A purple corn extract may be a potent therapeutic agent targeting abnormal angiogenesis in diabetic nephropathy leading to kidney failure.Dec 31, 2012

Açaí is a promising novel pharmacological therapeutic treatment for endometriosis.Dec 31, 2015

Administration of thymol afforded remarkable protection against high fat diet induced diabetic nephropathy.Feb 04, 2016

An aqueous extract of Bixa orellana showed anti-inflammatory properties in serotonin-induced acute inflammation.Dec 31, 2012

An immune-modulating diet in combination with chemotherapy prevented cancer cachexia without suppressing chemotherapeutic efficacy.Jul 01, 2015

Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.May 31, 2019

Astaxanthin inhibits homocysteine‑induced endothelial cell dysfunction.Apr 11, 2019

Astragaloside IV and curcumin alone and in combination significantly reduced mean tumor weight compared to vehicle control.Dec 31, 2016

Bamboo leaf extract could improve wound closure by 28 % at 12 hours and 54 % at 24 hours in mice.Nov 30, 2014

Betaine may potentially be used to delay the onset of complications associated with diabetic retinopathy via inhibition of retinal neovascularization in patients with diabetes.Jul 31, 2015

Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model). Jan 01, 2011

Camel milk inhibits inflammatory angiogenesis via downregulation of proangiogenic and proinflammatory cytokines in mice.Jun 30, 2014

Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.Sep 07, 2010

Curcumin inhibits lymphangiogenesis in vitro and in vivo, which could contribute to the antimetastatic effects of curcumin.Aug 26, 2015

Curcumin not only inhibits tumor angiogenesis, but also suppresses the production of VEGF in response to hypoxia.Aug 13, 2015

Curcumin treated animals had a significant reduction in tumor growth as measured by the decrease in size of the subcutaneous xenografts compared to untreated animals.Jun 07, 2015

Delphinidin is a promising compound to prevent pathologies associated with generation of vascular network in tumorigenesis.Dec 31, 2014

Dendrosomal curcumin has a chemoprotective effect on the breast cancer metastasis through suppression of NF-κB and its regulated gene products.Jul 04, 2015

Dietary administration of garcinol effectively reduced the tumor size and incidence in the mouse colon.Aug 31, 2014

EGCG can be developed into a potential agent for the prevention and treatment of smoking‑associated NSCLC.May 31, 2015

Ellagic acid exerted protective effects against carbon tetrachloride-induced cirrhosis through the inhibition of ROS formation and angiogenesis.Sep 30, 2017

Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.Jan 31, 2016

Essential oil of Pinus koraiensis leaves has anti-diabetic potential.Dec 31, 2012

Genistein mediated upregulation of CHOP impeded C/EBPβ interaction with the IL-6 promoter, thus disturbing the angiogenic microenvironment which inhibited tumor proliferation.May 31, 2015

Geraniol is an attractive candidate for the anti-angiogenic treatment of tumors.Dec 31, 2014

Ginkgo biloba exocarp extracts played the effects of anti-tumor and anti-metastatic depending upon the inhibition of tumor angiogenesis.Nov 03, 2016

Ginsenoside Rg3 nanoparticle may suppress the expression of VEGF, MMP-9 and HIF-1α in Lewis lung cancer mice.Jun 17, 2016

Ginsenoside Rg3 significantly inhibited growth and angiogenesis of ovarian cancer when used alone or combined with cyclophosphamide.Apr 04, 2007

Ginsenoside-Rg3 can down-regulate the expression of VEGF and TNF-α in retina.Dec 31, 2009

GinsenosideRg3 can be employed as an early intervention and a combining therapeutic aid to reduce inflammation and hypertrophic scar formation.Dec 31, 2013

Hesperidin as adjuvant therapy with DOX would enhance the therapeutic efficacy and alleviate the resistance to DOX in treatment of solid tumors.Jun 22, 2015

Honokiol has a significant anti-nociceptive activity through inhibition of anti-inflammatory mediators.Dec 31, 2017

Hyperbaric oxygen therapy could inhibit glioma cell proliferation and inflammatory cell infiltration.Oct 31, 2016

In vivo attenuation of angiogenesis in hepatocellular carcinoma by Nigella sativa.Feb 22, 2018

Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma.Dec 31, 2015

Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer.Jul 22, 2009

Lion's mane has antitumor effects in tumor-bearing mice.Sep 28, 2011

M. alba has protective effect on diabetic retinopathy.Apr 07, 2016

Matrine, one of the main components extracted from a traditional Chinese herb, Sophora flavescens has anti-cancer activity in an experimental model of metastatic breast cancer in mice.Jan 01, 2010

Mechanism and therapeutic effects of Saccharomyces boulardii on experimental colitis.Nov 30, 2018

Melittin exerts an antitumor effect on non‑small cell lung cancer cells.Aug 31, 2017

Metformin in combination with curcumin inhibits the growth, metastasis and angiogenesis of hepatocellular carcinoma.Aug 18, 2017

Methylsulfonylmethane suppresses breast cancer growth by down-regulating STAT3 and STAT5b pathways.Dec 31, 2011

Modulation of VEGF signaling in a mouse model of diabetes by xanthohumol.Dec 31, 2016

Morelloflavone is a potential inhibitor of tumor angiogenesis by targeting the Rho GTPase and ERK signaling pathways.Jan 14, 2009

Niacin was effective against iodoacetamide-induced colitis through ameliorating pathologic angiogenesis and inflammatory changes.Aug 01, 2017

Our results reveal Flavin7 (F7) had substantial tumour-suppression effects of 58 % and reduced tumour incidence by 24 % in this breast cancer model.Apr 30, 2015

Paeoniflorin is predicted to be a potential therapy for chronic hepatic diseases associated with fibrosis and angiogenesis.Jan 31, 2019

Palmitoylethanolamide may improve inflammation-driven angiogenesis in colonic mucosa.Dec 31, 2015

Parthenolide exerts inhibitory effects on angiogenesis through the downregulation of VEGF/VEGFRs in colorectal cancer.Apr 30, 2014

Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells.Oct 30, 2013

Piperlongumine suppresses growth and sensitizes pancreatic tumors to gemcitabine in a xenograft mouse model.Dec 13, 2015

Pretreatment with fucoxanthin may protect against UVB radiation-induced corneal disorders.Jan 06, 2016

Quercetin has a certain therapeutic effect on rats with diabetic retinopathy.Nov 30, 2017

Resveratrol counteracts systemic and local inflammation involved in early abdominal aortic aneurysm development.Nov 30, 2011

Sea buckthorn and St. John's wort oil may be a promising alternative for the treatment of endometriosis.Nov 30, 2016

Silibinin inhibits lung tumor angiogenesis in an animal model.Jun 20, 2006

Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma.Oct 03, 2017

Supplementation with lycopene-enriched tomato extract may counteract hepatocellular carcinoma progression or protect against disease onset.Oct 31, 2015

Tetrahydrocurcumin demonstrated an inhibitory effect against tumor angiogenesis in CaSki-implanted nude mice model.Dec 31, 2014

The administration of EGCG after sunitinib treatment represents a promising strategy for the treatment of cancer.Jan 04, 2016

Vascular Endothelial Growth Factor Inhibitors

View the Evidence:
174 Abstracts with Vascular Endothelial Growth Factor Inhibitors Research