Vascular Endothelial Growth Factor Inhibitors

Name	AC	CK
Curcumin	7	13
Bilberry	2	12
EGCG (Epigallocatechin gallate)	5	12
Cannabinoids	1	10
Delta-tetrahydrocannabinol (THC)	1	10
Polyphenols	3	8
Apple Polyphenols	1	5
Black Raspberry	1	5
Apigenin	3	4
Huaier (Trametes robiniophila murr)	2	3
Thymoquinone	2	3
Achiote	1	2
Anthocyanins	1	2
Ashwagandha	1	2
Bamboo	1	2
Betaine	1	2
Black Pepper	1	2
Boswellia	1	2
Camel Milk	1	2
Catechin	1	2
Chlorella (Algae)	1	2
Fruit Peel	1	2
Garcinia dulcis	1	2
Garcinia indica	1	2
Genistein	1	2
Ginger	1	2
Gingerol	1	2
Hesperidin	1	2
Lion's Mane (Hericium Erinaceus)	1	2
Long Pepper	1	2
Lycopene	1	2
Melatonin	2	2
Nobiletin	1	2
Sophora Flavescens	1	2
Spirulina	1	2
Tetrahydrocurcumin	1	2
Theaflavins	2	2
Thymol	1	2
Tomato	1	2
Triphala	1	2
Whey	1	2
Black Tea	1	1
Blueberry	1	1
Caffeic acid phenethyl ester	1	1
Cannabidiol	1	1
Cinnamon	1	1
Ginseng (Korean)	1	1
Guggul	1	1
Holy Basil	1	1
Luteolin	1	1
Pomegranate Peel	1	1
Prunella vulgaris.	1	1
Quercetin	1	1
Resveratrol	1	1
Schisandra	1	1

[+]

Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

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Pubmed Data : Drug Des Devel Ther. 2016 ;10:2239-53. Epub 2016 Jul 11. PMID: 27468227

Article Published Date : Dec 31, 2015

Study Type : Animal Study

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Substances : Thymoquinone

Diseases : Colorectal Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemoprotective Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Vascular Endothelial Growth Factor Inhibitors, Wnt/β-catenin signaling pathway modulation

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Gene Expression Regulation

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Planta Med. 2014 Dec ;80(18):1678-84. Epub 2014 Oct 15. PMID: 25317773

Article Published Date : Nov 30, 2014

Study Type : Animal Study

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Substances : Bamboo

Diseases : Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

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Betaine may potentially be used to delay the onset of complications associated with diabetic retinopathy via inhibition of retinal neovascularization in patients with diabetes.Jul 31, 2015

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Pubmed Data : Oncotarget. 2015 Jun 8. Epub 2015 Jun 8. PMID: 26116834

Article Published Date : Jun 07, 2015

Study Type : Animal Study, In Vitro Study

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Substances : Curcumin

Diseases : Leukemia: Chronic myelogenous leukemia (CML)

Pharmacological Actions : Antiproliferative , Apoptotic, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Exosomes

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Delphinidin is a promising compound to prevent pathologies associated with generation of vascular network in tumorigenesis.Dec 31, 2014

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Pubmed Data : Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID: 26919952

Article Published Date : Jan 31, 2016

Study Type : Animal Study

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Substances : Ginsenosides

Diseases : Breast Cancer

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor C Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Natural Substance/Drug Synergy

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Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats.Jun 30, 2012

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Pubmed Data : Biochem Pharmacol. 2012 Jul 1 ;84(1):88-92. Epub 2012 Mar 30. PMID: 22484312

Article Published Date : Jun 30, 2012

Study Type : Animal Study

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Substances : Eriodictyol

Diseases : Diabetic Retinopathy

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Essential oil of Pinus koraiensis leaves has anti-diabetic potential.Dec 31, 2012

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Pubmed Data : Turk J Med Sci. 2018 Feb 23 ;48(1):178-186. Epub 2018 Feb 23. PMID: 29479981

Article Published Date : Feb 22, 2018

Study Type : Animal Study

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Substances : Nigella sativa (aka Black Seed)

Diseases : Liver Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

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Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer.Nov 30, 2019

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Pubmed Data : Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):3465-3477. PMID: 31432702

Article Published Date : Nov 30, 2019

Study Type : Animal Study, In Vitro Study

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Substances : Ligustrazine

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Anti-metastatic, Chemotherapeutic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Chemothapeutic Synergy: Paclitaxel

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Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma.Dec 31, 2015

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Pubmed Data : Sci Rep. 2016 ;6:21731. Epub 2016 Feb 25. PMID: 26911838

Article Published Date : Dec 31, 2015

Study Type : Animal Study

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Substances : Apigenin

Diseases : Cancer Metastasis, Melanoma

Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, STAT3 Inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer.Jul 22, 2009

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Pubmed Data : BMC Cancer. 2009 Jul 23 ;9:250. Epub 2009 Jul 23. PMID: 19624862

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Pubmed Data : Am J Chin Med. 2010;38(6):1115-30. PMID: 21061465

Article Published Date : Jan 01, 2010

Study Type : Animal Study

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Substances : Sophora Flavescens

Diseases : Breast Cancer, Breast Cancer: Metastatic, Cancer Metastasis

Pharmacological Actions : Anti-Angiogenic, Anti-Proliferative, Vascular Endothelial Growth Factor Inhibitors

[+]

Mechanism and therapeutic effects of Saccharomyces boulardii on experimental colitis.Nov 30, 2018

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Pubmed Data : Mol Nutr Food Res. 2017 04 ;61(4). Epub 2017 Jan 30. PMID: 27921359

Article Published Date : Dec 31, 2016

Study Type : Animal Study

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Substances : Xanthohumol

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Vascular Endothelial Growth Factor Inhibitors

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Morelloflavone is a potential inhibitor of tumor angiogenesis by targeting the Rho GTPase and ERK signaling pathways.Jan 14, 2009

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Pubmed Data : Cancer Res. 2009 Jan 15 ;69(2):518-25. PMID: 19147565

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Pubmed Data : Eur J Nutr. 2015 May 1. Epub 2015 May 1. PMID: 25930965

Pubmed Data : J Surg Res. 2011 Dec ;171(2):e237-46. Epub 2011 Aug 24. PMID: 21962734

Article Published Date : Nov 30, 2011

Study Type : Animal Study

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Substances : Resveratrol

Diseases : Aneurysm: Aortic

Pharmacological Actions : Antioxidants, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Sea buckthorn and St. John's wort oil may be a promising alternative for the treatment of endometriosis.Nov 30, 2016

Pubmed Data : Int J Mol Sci. 2016 Dec 9 ;17(12). Epub 2016 Dec 9. PMID: 27941690

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Vis. 2016 ;22:599-609. Epub 2016 Jun 9. PMID: 27293376

Article Published Date : Dec 31, 2015

Study Type : Animal Study

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Substances : Ginger, Gingerol

Diseases : Diabetic Complications

Pharmacological Actions : Anti-Angiogenic, Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

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20(S)-Rg3 can inhibit the proliferation of U266 cells by cell cycle arrest in G1 phase and induce cell apoptosis in multiple myeloma cells.May 31, 2014

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Pubmed Data : Zhonghua Xue Ye Xue Za Zhi. 2014 Jun ;35(6):519-23. PMID: 24985176

Article Published Date : May 31, 2014

Study Type : In Vitro Study

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Substances : Ginsenosides

Diseases : Multiple Myeloma

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Vascular Endothelial Growth Factor Inhibitors

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A hydroalcoholic extract of oak acorn shell acts as a potent antiangiogenic agent.Feb 28, 2013

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Pubmed Data : Pharm Biol. 2013 Mar ;51(3):361-8. Epub 2012 Nov 8. PMID: 23137183

Article Published Date : Feb 28, 2013

Study Type : In Vitro Study

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Substances : Oak

Diseases : Cancers: All

Pharmacological Actions : Anti-Angiogenic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Plant Extracts

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Antiangiogenic phytochemicals and medicinal herbs may have value in the treatment of endometriosis.Jan 01, 2011

Article Published Date : Mar 31, 2011

Study Type : In Vitro Study

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Substances : Beta-Elemene

Diseases : Melanoma

Pharmacological Actions : Anti-Angiogenic, Anti-metastatic, Vascular Endothelial Growth Factor Inhibitors

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Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors.Mar 14, 2007

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Pubmed Data : Oxid Med Cell Longev. 2016 ;2016:3017108. Epub 2015 Nov 30. PMID: 26697130

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

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Substances : Caffeic acid phenethyl ester

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Synergy with Tamoxifen

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Cannabidiol exerts a potent anti-angiogenic effect by widely affecting several pathways involved in this process.Oct 31, 2012

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Pubmed Data : Biomed Pharmacother. 2018 Sep 11 ;108:65-75. Epub 2018 Sep 11. PMID: 30216802

Article Published Date : Sep 10, 2018

Study Type : In Vitro Study

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Substances : Benzyl isothiocyanate

Diseases : Liver Cancer

Pharmacological Actions : Anti-metastatic, Chemopreventive, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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Chlorogenic acid can regulate theapoptosis of non-small lung cancer through Notch pathway.Aug 19, 2017

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Pubmed Data : Zhongguo Fei Ai Za Zhi. 2017 Aug 20 ;20(8):555-561. PMID: 28855037

Article Published Date : Aug 19, 2017

Study Type : In Vitro Study

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Substances : Chlorogenic Acid

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, MicroRNA modulator, Vascular Endothelial Growth Factor Inhibitors

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Chlorogenic acid may act as a chemosensitizing agent leading to cancer growth suppression.Dec 31, 2017

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Pubmed Data : Oncol Rep. 2016 Dec 7. Epub 2016 Dec 7. PMID: 27959445

Article Published Date : Dec 06, 2016

Study Type : In Vitro Study

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Substances : Delphinidin

Diseases : Lung Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Angiogenesis Inhibitors, Delphinidin, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, lung cancer, Vascular Endothelial Growth Factor Inhibitors

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Diosgenin inhibits migration and invasion of human prostate cancer PC-3 cells.Dec 31, 2010

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Pubmed Data : Sci Rep. 2016 ;6:20049. Epub 2016 Feb 1. PMID: 26831282

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

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Substances : Huaier (Trametes robiniophila murr)

Diseases : Breast Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Dose Response

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In this mini-review, selected flavonoids which are a group of plant polyphenols that are able to regulate angiogenesis in vitro and in vivo systems are discussed.Dec 31, 2014

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Pubmed Data : Mini Rev Med Chem. 2015 ;15(6):479-89. PMID: 25873069

Article Published Date : Dec 31, 2014

Study Type : Review

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Substances : Apigenin, EGCG (Epigallocatechin gallate), Luteolin, Quercetin

Diseases : Cancers: All

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

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Click here to read the entire abstract

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Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2005 Mar ;30(5):357-60. PMID: 15806969

Article Published Date : Feb 28, 2005

Study Type : In Vitro Study

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Substances : Ginsenosides

Diseases : Lung Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Gene Expression Regulation

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The present data suggests a potential clinical impact of wogonin for ovarian cancer patients.Dec 31, 2016

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Pubmed Data : Mar Drugs. 2017 Jun 20 ;15(6). Epub 2017 Jun 20. PMID: 28632184

Article Published Date : Jun 19, 2017

Study Type : In Vitro Study

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Substances : Fucoidan

Diseases : Osteosarcoma

Pharmacological Actions : Angiogenesis Inhibitors, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Bone Regeneration

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Pubmed Data : Int Immunopharmacol. 2016 May 27 ;38:70-80. Epub 2016 May 27. PMID: 27240137

Article Published Date : May 26, 2016

Study Type : In Vitro Study

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Substances : Thymoquinone

Diseases : Asthma

Pharmacological Actions : Anti-Inflammatory Agents, Vascular Endothelial Growth Factor Inhibitors

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This study indicated that a hydroalcoholic extract of P. harmala seeds contains a potent anti-angiogenic component.May 31, 2015

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Pubmed Data : Pharm Biol. 2015 Jun ;53(6):855-61. Epub 2014 Dec 4. PMID: 25471082

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Pubmed Data : Mol Cancer Res. 2008 Jun ;6(6):1059-70. PMID: 18567808

Article Published Date : May 31, 2008

Study Type : In Vitro Study

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Substances : Thymoquinone

Diseases : Acute Myeloid Leukemia, Cancers: All

Pharmacological Actions : Antiproliferative , Apoptotic, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors

Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Doxorubicin

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Ursolic acid exerted chemosensitizing effects in colon cancer cells.Aug 31, 2016

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Pubmed Data : J Zhejiang Univ Sci B. 2016 Sep ;17(9):672-82. PMID: 27604859

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Pubmed Data : Pharmacogn Mag. 2018 Jan ;13(Suppl 4):S731-S736. Epub 2018 Jan 31. PMID: 29491625

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Zerumbone

Diseases : Liver Cancer

Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor Inhibitors

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View the Evidence: 204 Abstracts with Vascular Endothelial Growth Factor Inhibitors Research

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Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patients with acute leukemia.Dec 31, 2013

Intake of bilberries has an ameliorating effect on some markers of gingival inflammation reducing gingivitis to a similar extent compared to standard of care.Dec 31, 2014

Local ice cryotherapy had beneficial effects in human non-septic knee arthritis.Jul 29, 2019

Powdered Nigella sativa has potent beneficial effects in improving thyroid status and anthropometric variables.Nov 15, 2016

Resveratrol may improve some outcomes of PCOS patients.Jul 20, 2019

Vitamin D Decreases Serum VEGF Correlating with Clinical Improvement in Vitamin D-Deficient Women with polycystic ovary syndrome.Mar 27, 2017

A Black Raspberry extract could prevent the initiation, promotion, and progression of carcinogenesis in the digestive tract and esophagus.Oct 27, 2014

Melatonin has anti-angiogenic effects at different steps of the angiogenic process in SH-SY5Y neuroblastoma cells.Feb 13, 2017

VEGF is a key molecular target for specific polyphenols found in tea, apples and cocoa which potently inhibit VEGF signalling and angiogenesis at physiological concentrations.Feb 28, 2015

5-FU and thymoquinone combination therapy resulted in a more significant reduction on AOM-induced colorectal tumors.Dec 31, 2015

A ashwagandha water extract suppressed the tumor growth of glioma cells.Jul 25, 2015

A Huaier polysaccharide restrains hepatocellular carcinoma growth and metastasis.Mar 31, 2015

A purple corn extract may be a potent therapeutic agent targeting abnormal angiogenesis in diabetic nephropathy leading to kidney failure.Dec 31, 2012

Açaí is a promising novel pharmacological therapeutic treatment for endometriosis.Dec 31, 2015

Administration of thymol afforded remarkable protection against high fat diet induced diabetic nephropathy.Feb 04, 2016

An aqueous extract of Bixa orellana showed anti-inflammatory properties in serotonin-induced acute inflammation.Dec 31, 2012

An immune-modulating diet in combination with chemotherapy prevented cancer cachexia without suppressing chemotherapeutic efficacy.Jul 01, 2015

Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.May 31, 2019

Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma.Nov 11, 2019

Astaxanthin inhibits homocysteine‑induced endothelial cell dysfunction.Apr 11, 2019

Astragaloside IV and curcumin alone and in combination significantly reduced mean tumor weight compared to vehicle control.Dec 31, 2016

Bamboo leaf extract could improve wound closure by 28 % at 12 hours and 54 % at 24 hours in mice.Nov 30, 2014

Betaine may potentially be used to delay the onset of complications associated with diabetic retinopathy via inhibition of retinal neovascularization in patients with diabetes.Jul 31, 2015

Biochanin A regulates the growth and migration of NSCLC through suppressing the VEGF/VEGFR2 signaling pathway.Jul 22, 2018

Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model). Jan 01, 2011

Camel milk inhibits inflammatory angiogenesis via downregulation of proangiogenic and proinflammatory cytokines in mice.Jun 30, 2014

Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.Sep 07, 2010

Curcumin inhibits lymphangiogenesis in vitro and in vivo, which could contribute to the antimetastatic effects of curcumin.Aug 26, 2015

Curcumin not only inhibits tumor angiogenesis, but also suppresses the production of VEGF in response to hypoxia.Aug 13, 2015

Curcumin treated animals had a significant reduction in tumor growth as measured by the decrease in size of the subcutaneous xenografts compared to untreated animals.Jun 07, 2015

Delphinidin is a promising compound to prevent pathologies associated with generation of vascular network in tumorigenesis.Dec 31, 2014

Dendrosomal curcumin has a chemoprotective effect on the breast cancer metastasis through suppression of NF-κB and its regulated gene products.Jul 04, 2015

Dietary administration of garcinol effectively reduced the tumor size and incidence in the mouse colon.Aug 31, 2014

EGCG can be developed into a potential agent for the prevention and treatment of smoking‑associated NSCLC.May 31, 2015

Ellagic acid exerted protective effects against carbon tetrachloride-induced cirrhosis through the inhibition of ROS formation and angiogenesis.Sep 30, 2017

Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.Jan 31, 2016

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats.Jun 30, 2012

Essential oil of Pinus koraiensis leaves has anti-diabetic potential.Dec 31, 2012

Genistein mediated upregulation of CHOP impeded C/EBPβ interaction with the IL-6 promoter, thus disturbing the angiogenic microenvironment which inhibited tumor proliferation.May 31, 2015

Geraniol is an attractive candidate for the anti-angiogenic treatment of tumors.Dec 31, 2014

Ginkgo biloba exocarp extracts played the effects of anti-tumor and anti-metastatic depending upon the inhibition of tumor angiogenesis.Nov 03, 2016

Ginsenoside Rg3 nanoparticle may suppress the expression of VEGF, MMP-9 and HIF-1α in Lewis lung cancer mice.Jun 17, 2016

Ginsenoside Rg3 significantly inhibited growth and angiogenesis of ovarian cancer when used alone or combined with cyclophosphamide.Apr 04, 2007

Ginsenoside-Rg3 can down-regulate the expression of VEGF and TNF-α in retina.Dec 31, 2009

GinsenosideRg3 can be employed as an early intervention and a combining therapeutic aid to reduce inflammation and hypertrophic scar formation.Dec 31, 2013

Hesperidin as adjuvant therapy with DOX would enhance the therapeutic efficacy and alleviate the resistance to DOX in treatment of solid tumors.Jun 22, 2015

Honokiol has a significant anti-nociceptive activity through inhibition of anti-inflammatory mediators.Dec 31, 2017

Hyperbaric oxygen therapy could inhibit glioma cell proliferation and inflammatory cell infiltration.Oct 31, 2016

In vivo attenuation of angiogenesis in hepatocellular carcinoma by Nigella sativa.Feb 22, 2018

Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer.Nov 30, 2019

Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma.Dec 31, 2015

Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer.Jul 22, 2009

Lion's mane has antitumor effects in tumor-bearing mice.Sep 28, 2011

M. alba has protective effect on diabetic retinopathy.Apr 07, 2016

Matrine, one of the main components extracted from a traditional Chinese herb, Sophora flavescens has anti-cancer activity in an experimental model of metastatic breast cancer in mice.Jan 01, 2010

Mechanism and therapeutic effects of Saccharomyces boulardii on experimental colitis.Nov 30, 2018

Melittin exerts an antitumor effect on non‑small cell lung cancer cells.Aug 31, 2017

Metformin in combination with curcumin inhibits the growth, metastasis and angiogenesis of hepatocellular carcinoma.Aug 18, 2017

Methylsulfonylmethane suppresses breast cancer growth by down-regulating STAT3 and STAT5b pathways.Dec 31, 2011

Modulation of VEGF signaling in a mouse model of diabetes by xanthohumol.Dec 31, 2016

Morelloflavone is a potential inhibitor of tumor angiogenesis by targeting the Rho GTPase and ERK signaling pathways.Jan 14, 2009

Musa acuminata lectin protein has promising anticancer potential.Dec 31, 2018

Myricetin could significantly inhibit tumor angiogenesis and has potential as a chemopreventive agent.Jul 01, 2019

Niacin was effective against iodoacetamide-induced colitis through ameliorating pathologic angiogenesis and inflammatory changes.Aug 01, 2017

Our results reveal Flavin7 (F7) had substantial tumour-suppression effects of 58 % and reduced tumour incidence by 24 % in this breast cancer model.Apr 30, 2015

Paeoniflorin is predicted to be a potential therapy for chronic hepatic diseases associated with fibrosis and angiogenesis.Jan 31, 2019

Palmitoylethanolamide may improve inflammation-driven angiogenesis in colonic mucosa.Dec 31, 2015

Parthenolide exerts inhibitory effects on angiogenesis through the downregulation of VEGF/VEGFRs in colorectal cancer.Apr 30, 2014

Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells.Oct 30, 2013

Piperlongumine suppresses growth and sensitizes pancreatic tumors to gemcitabine in a xenograft mouse model.Dec 13, 2015

Pretreatment with fucoxanthin may protect against UVB radiation-induced corneal disorders.Jan 06, 2016

Vascular Endothelial Growth Factor Inhibitors

View the Evidence:
204 Abstracts with Vascular Endothelial Growth Factor Inhibitors Research