Camptothecin

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7 Diseases Researched for Camptothecin

Name	AC	CK
Liver Cancer	1	2
Cancers: Drug Resistant	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Non-Small-Cell Lung Carcinoma	1	1
Retinoblastoma	1	1
Sclerosis: Systemic	1	1
Thyroid Cancer	1	1

6 Pharmacological Actions Researched for Camptothecin

Name	AC	CK
Apoptotic	2	3
Antiproliferative	1	2
Chemopreventive	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Chemosensitizer	1	1
Topoisomerase I inhibitor	1	1

Research Articles 8
Cumulative Knowledge Score 12
Overall Research Rating GOOD

View the Evidence:
8 Abstracts with Camptothecin Research

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Camptothecin effectively treats obesity in mice through GDF15 induction.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS Biol. 2022 02 ;20(2):e3001517. Epub 2022 Feb 24. PMID: 35202387

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Camptothecin

Diseases : Obesity

Additional Keywords : Anti-Obesity Agents

[+]

Camptothecin encapsulated with N-trimethyl chitosan exhibits anti-cancer properties in a preclinical mouse model of liver cancer.Nov 01, 2010

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Pubmed Data : Cancer Lett. 2010 Nov 1 ;297(1):56-64. Epub 2010 May 23. PMID: 20546992

Article Published Date : Nov 01, 2010

Study Type : Animal Study

Additional Links

Substances : Camptothecin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive, Matrix metalloproteinase-2 (MMP-2) inhibitor

[+]

Camptothecin acts synergistically with imatinib and overcomes imatinib resistance in chronic myelogenous leukemia (CML) cells.Jul 08, 2007

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Pubmed Data : Cancer Lett. 2007 Jul 8;252(1):75-85. Epub 2007 Jan 16. PMID: 17223257

Article Published Date : Jul 08, 2007

Study Type : In Vitro Study

Additional Links

Substances : Camptothecin

Diseases : Cancers: Drug Resistant, Leukemia: Acute myelogenous leukemia (AML)

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug-Plant-Vitamin Synergies

[+]

Camptothecin demonstrates anti-tumor activity against thyroid cancer cells. May 01, 2009

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Pubmed Data : Int J Biochem Cell Biol. 2009 May;41(5):1165-72. Epub 2008 Nov 5. PMID: 19027085

Article Published Date : May 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Camptothecin

Diseases : Thyroid Cancer

[+]

Camptothecin induces programmed cell death of human retinoblastoma cellsJan 01, 2011

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Pubmed Data : Curr Eye Res. 2011 Jan;36(1):71-7. PMID: 21174601

Article Published Date : Jan 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Camptothecin

Diseases : Retinoblastoma

Pharmacological Actions : Apoptotic

[+]

Camptothecin may have therapeutic value in the treatment of non-small cell lung cancer. Aug 01, 2009

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Pubmed Data : Anticancer Res. 2009 Aug;29(8):2905-11. PMID: 19661294

Article Published Date : Aug 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Camptothecin

Diseases : Non-Small-Cell Lung Carcinoma

Additional Keywords : Drug-Plant-Vitamin Synergies

[+]

Camptothecin, a natural topoisomerase I inhibitor, may be effective in limiting fibrosis in patietns with systemic sclerosis. Jan 01, 2003

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Pubmed Data : Nutr Cancer. 2003;45(2):195-202. PMID: 11549373

Article Published Date : Jan 01, 2003

Study Type : In Vitro Study

Additional Links

Substances : Camptothecin

Diseases : Sclerosis: Systemic

Pharmacological Actions : Topoisomerase I inhibitor

[+]

Treatment of HT29 human colorectal cancer cell line with nanocarrier-encapsulated camptothecin.Nov 12, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2021 Nov 13 ;22(22). Epub 2021 Nov 13. PMID: 34830168

Article Published Date : Nov 12, 2021

Study Type : In Vitro Study

Additional Links

Substances : Camptothecin

Diseases : Colorectal Cancer

Pharmacological Actions : Chemopreventive, Histone deacetylase inhibitor, Wnt/β-catenin signaling pathway modulation

Additional Keywords : Epigenetic Modification In Cancer

Research Articles 8
Cumulative Knowledge Score 12
Overall Research Rating GOOD

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Focus Your Research

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View the Evidence: 8 Abstracts with Camptothecin Research

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Camptothecin effectively treats obesity in mice through GDF15 induction.Dec 31, 2021

Camptothecin encapsulated with N-trimethyl chitosan exhibits anti-cancer properties in a preclinical mouse model of liver cancer.Nov 01, 2010

Camptothecin acts synergistically with imatinib and overcomes imatinib resistance in chronic myelogenous leukemia (CML) cells.Jul 08, 2007

Camptothecin demonstrates anti-tumor activity against thyroid cancer cells. May 01, 2009

Camptothecin induces programmed cell death of human retinoblastoma cellsJan 01, 2011

Camptothecin may have therapeutic value in the treatment of non-small cell lung cancer. Aug 01, 2009

Camptothecin, a natural topoisomerase I inhibitor, may be effective in limiting fibrosis in patietns with systemic sclerosis. Jan 01, 2003

Treatment of HT29 human colorectal cancer cell line with nanocarrier-encapsulated camptothecin.Nov 12, 2021

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Camptothecin

View the Evidence:
8 Abstracts with Camptothecin Research