Citrus naringin

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15 Diseases Researched for Citrus naringin
NameACCKFocus
DNA damage23Locked
Acetaminophen (Tylenol) Toxicity 12Locked
Diabetes Mellitus: Type 212Locked
HIV Drug-Induced Toxicity 12Locked
Osteoporosis12Locked
Oxidative Stress12Locked
Radiation Induced Illness12Locked
Androgen-Induced Diseases11Locked
Cancers: Multi-Drug Resistant11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Cervical Cancer11Locked
Chemotherapy-Induced Toxicity: Bleomycin11Locked
Gingivitis11Locked
Osteoporosis: Male11Locked
Peridontal Infection11Locked
10 Pharmacological Actions Researched for Citrus naringin
NameACCKFocus
Antioxidants12Locked
Hepatoprotective12Locked
MicroRNA modulator12Locked
Radioprotective12Locked
Renoprotective12Locked
Anti-Androgen11Locked
Anti-Bacterial Agents11Locked
Antiproliferative 11Locked
Apoptotic11Locked
Genoprotective11Locked

View the Evidence:
78 Abstracts with Citrus naringin Research

[+]

This supports the available scientific evidence on the beneficial role of naringin in the management of various neurological ailments.Sep 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Oct ;94:909-929. Epub 2017 Aug 16. PMID: 28810519
Article Published Date : Sep 30, 2017
Study Type : Meta Analysis, Review
Additional Links
Substances : Citrus naringin
Diseases : Brain: Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Naringin protects against high glucose-induced human endothelial cell injury.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2017 ;42(6):2540-2551. Epub 2017 Aug 23. PMID: 28848146
Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Citrus naringin
Diseases : Diabetes: Oxidative Stress, Diabetic Complications
Pharmacological Actions : Antioxidants
[+]

These findings indicate a novel role for naringin in protecting against fructose-induced cardiac hypertrophy.Jun 20, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Jun 21 ;8(1):9464. Epub 2018 Jun 21. PMID: 29930336
Article Published Date : Jun 20, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Cardiac Hypertrophy, High Fructose Diet
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
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Dried peel powder of C. kawachiensis had a neuroprotective effect against ischemic brain injury. Apr 03, 2018

Pubmed Data : Biosci Biotechnol Biochem. 2018 Apr 4:1-9. Epub 2018 Apr 4. PMID: 29618282
Article Published Date : Apr 03, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin, Citrus Peel , Fruit: All
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Cerebral Ischemia, Citrus naringin, Citrus Peel, Fruit: All, Neuroprotective Agents
[+]

Efficiency of naringin against reproductive toxicity and testicular damages induced by bisphenol A.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2019 Mar ;22(3):315-523. PMID: 31156794
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Bisphenol Toxicity, Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants, Cytoprotective
Problem Substances : Bisphenol A
[+]

Naringin alleviates early brain injury after experimental subarachnoid hemorrhage.Jun 30, 2017

Pubmed Data : Brain Res Bull. 2017 Jul ;133:42-50. Epub 2016 Dec 21. PMID: 28011192
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Oxidative Stress, Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Naringin alleviates H2O2-induced apoptosis via the PI3K/Akt pathway in rat nucleus pulposus-derived mesenchymal stem cells.Jul 10, 2019

Pubmed Data : Connect Tissue Res. 2019 Jul 11:1-14. Epub 2019 Jul 11. PMID: 31294637
Article Published Date : Jul 10, 2019
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic
Additional Keywords : Mesenchymal Stem Cells
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Naringin also regulates endothelial cell function and promotes angiogenesis to exert its anti‑osteoporotic effect.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2017 Dec ;40(6):1741-1749. Epub 2017 Sep 28. PMID: 29039439
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic
[+]

Naringin ameliorated oxidative stress and nucleoside reverse transcriptase inhibitors-induced mitochondrial damage.Dec 31, 2015

Pubmed Data : Curr HIV Res. 2016 ;14(6):506-516. PMID: 27197616
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Citrus naringin, Vitamin E
Diseases : HIV Drug-Induced Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Antioxidants, Citrus naringin, HIV Drug-Induced Toxicity, oxidative stress, reactive oxygen species (ROS), VITAMIN E
[+]

Naringin ameliorates endothelial dysfunction in fructose-fed rats.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Mar ;15(3):3140-3146. Epub 2018 Jan 17. PMID: 29456717
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Endothelial Dysfunction
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Naringin and vitamin C demonstrates antihyperglycemic effects in the rat model of type 2 diabetes.Aug 01, 2008

Pubmed Data : J Appl Toxicol. 2008 Aug;28(6):806-13. PMID: 18344197
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetes Mellitus: Type 2
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Naringin attentuates retinoic acid-induced osteoporosis in an animal model. Jan 01, 2007

Pubmed Data : Am J Chin Med. 2007;35(4):663-7. PMID: 17708632
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Osteoporosis
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Naringin attenuates alcoholic liver injury by reducing lipid accumulation and oxidative stress.Dec 31, 2018

Pubmed Data : Life Sci. 2019 Jan 1 ;216:305-312. Epub 2018 Jul 18. PMID: 30031061
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective
[+]

Naringin attenuates diabetic retinopathy by inhibiting inflammation and oxidative stress.Jun 30, 2017

Pubmed Data : Iran J Basic Med Sci. 2017 Jul ;20(7):813-821. PMID: 28852447
Article Published Date : Jun 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetic Retinopathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
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Naringin can protect nucleus pulposus cells against apoptosis and ameliorate Intervertebral disc degeneration in vivo.Oct 03, 2018

Pubmed Data : Am J Chin Med. 2018 Oct 4:1-20. Epub 2018 Oct 4. PMID: 30284462
Article Published Date : Oct 03, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Intervertebral Disk Displacement
Pharmacological Actions : Anti-Apoptotic
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Naringin could be a potential therapeutic agent to prevent the brain from ischemia-reperfusion injury.Nov 30, 2018

Pubmed Data : Mol Neurobiol. 2018 Dec ;55(12):9029-9042. Epub 2018 Apr 7. PMID: 29627876
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
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Naringin enhances reverse cholesterol transport in high fat/low streptozocin induced diabetic rats.Apr 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 May ;101:430-437. Epub 2018 Mar 22. PMID: 29501765
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetes Mellitus: Type 2, Diabetic Complications
Pharmacological Actions : Anti-atherogenic
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Naringin had a protective effect against cardiotoxicity induced by BPA.Sep 27, 2018

Pubmed Data : Drug Chem Toxicol. 2018 Sep 28:1-11. Epub 2018 Sep 28. PMID: 30264589
Article Published Date : Sep 27, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Bisphenol Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Hypolipidemic
Problem Substances : Bisphenol A
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Naringin has a protective effect against Intracerebral hemorrhage-induced neurocognitive deficits.Dec 31, 2016

Pubmed Data : Pharmacology. 2017 ;100(3-4):172-187. Epub 2017 Jul 1. PMID: 28668949
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Cerebral Hemorrhage, Hyperalgesia, Lipid Peroxidation
Pharmacological Actions : Neuroprotective Agents, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
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Naringin has potential antihyperglycemic activity in high-fat diet/low-dose streptozotocin-induced diabetic rats.Jun 30, 2017

Pubmed Data : Gen Physiol Biophys. 2017 Jul ;36(3):343-352. PMID: 28635611
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetic Complications, High Fat Diet
Pharmacological Actions : Hypoglycemic Agents
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Naringin improved sepsis-induced intestinal injury.Jun 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Jul ;103:50-58. Epub 2018 Apr 7. PMID: 29635128
Article Published Date : Jun 30, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
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Naringin inhibits ovarian tumor growth by promoting apoptosis.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Jul ;16(1):59-64. Epub 2018 May 2. PMID: 29928387
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
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Naringin is a promising therapeutic candidate for hepatic fibrosis.Oct 14, 2017

Pubmed Data : Life Sci. 2017 Oct 15 ;187:50-57. Epub 2017 Aug 19. PMID: 28830755
Article Published Date : Oct 14, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Liver Cirrhosis
Pharmacological Actions : Anti-Fibrotic, Antioxidants, Hepatoprotective, Interleukin-6 Downregulation
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Naringin may be a promising agent for the treatment of physical fatigue.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2017 Dec ;55(1):423-427. PMID: 27937032
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Fatigue
Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor
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Naringin may protect myocardium in diabetic rats by reducing mitochondrial oxidative stress injuries.Jan 31, 2018

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2018 Feb ;43(3):596-602. PMID: 29600628
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Cardiomyopathy, Diabetes: Oxidative Stress, Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective
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Naringin prevented colitis and colorectal carcinogenesisMar 25, 2018

Pubmed Data : Cancer Biol Ther. 2018 Mar 26:1-10. Epub 2018 Mar 26. PMID: 29580144
Article Published Date : Mar 25, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Colitis, Colorectal Cancer: Prevention
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents
[+]

Naringin prevents HIV-1 protease inhibitors-induced metabolic complications in vivo.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(11):e0183355. Epub 2017 Nov 9. PMID: 29121676
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : HIV Drug-Induced Toxicity
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Naringin promotes fracture healing through stimulation of angiogenesis.Jan 04, 2017

Pubmed Data : Chem Biol Interact. 2017 Jan 5 ;261:11-17. Epub 2016 Nov 8. PMID: 27833010
Article Published Date : Jan 04, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Bone Fractures, Osteoporosis
Pharmacological Actions : Angiogenesis Inducing Agents
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Naringin protects against bone loss in steroid-treated inflammatory bowel disease in a rat model.Jul 14, 2018

Pubmed Data : Arch Biochem Biophys. 2018 Jul 15 ;650:22-29. Epub 2018 May 17. PMID: 29753722
Article Published Date : Jul 14, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : MicroRNA modulator, Osteoprotective
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Naringin protects against cyclophosphamide-induced hepatotoxicity and nephrotoxicity.May 14, 2018

Pubmed Data : Environ Sci Pollut Res Int. 2018 May 15. Epub 2018 May 15. PMID: 29766429
Article Published Date : May 14, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Cyclooxygenase 2 Inhibitors, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Renoprotective
[+]

Naringin protects against lipopolysaccharide-induced cardiac injury in mice.Nov 30, 2016

Pubmed Data : Environ Toxicol Pharmacol. 2016 Dec ;48:1-6. Epub 2016 Sep 13. PMID: 27716530
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
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Naringin protects against perfluorooctane sulfonate-induced liver injury.Nov 30, 2018

Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:140-147. Epub 2018 Oct 10. PMID: 30316072
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Chemically-Induced Liver Damage, Perfluorooctane Sulfonate-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Perfluorooctane sulfonate (PFOS)
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Naringin protects against steroid‑induced avascular necrosis of the femoral head.Jan 31, 2018

Pubmed Data : Mol Med Rep. 2018 Feb ;17(2):3328-3335. Epub 2017 Dec 11. PMID: 29257271
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Steroid-Induced Toxicity
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Naringin protects against the liver damage caused by streptozotocin-induced diabetes.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:95-102. Epub 2018 May 28. PMID: 29852394
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetes Mellitus: Type 1: Prevention, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Hepatoprotective, Interleukin-6 Downregulation
[+]

Naringin protects viscera from ischemia/reperfusion injury by regulating the nitric oxide level in a rat model.Dec 31, 2016

Pubmed Data : Biotech Histochem. 2017 ;92(4):252-263. Epub 2017 Apr 20. PMID: 28426254
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Ischemia
Pharmacological Actions : Nitric Oxide Inhibitor
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Naringin regulates glutamate-nitric oxide cGMP pathway in ammonium chloride induced neurotoxicity.Nov 30, 2016

Pubmed Data : Biomed Pharmacother. 2016 Dec ;84:1717-1726. Epub 2016 Nov 9. PMID: 27836465
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Aluminum Toxicity , Lipid Peroxidation, Neurodegenerative Diseases
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum Chloride
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Naringin treatment reduced histological alteration induced by APAP in the liver and kidney.Apr 05, 2016

Pubmed Data : Ren Fail. 2016 Apr 6:1-14. Epub 2016 Apr 6. PMID: 27050864
Article Published Date : Apr 05, 2016
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Hepatoprotective, MicroRNA modulator, Renoprotective
Problem Substances : Paracetamol
[+]

Naringin was found to be an effective antidiabetic agent which increased Insulin gene expression and insulin secretion.Dec 31, 2017

Pubmed Data : Cells Tissues Organs. 2018 ;206(3):133-143. Epub 2019 Mar 18. PMID: 30884485
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Insulin Resistance
Pharmacological Actions : Insulin-releasing
Additional Keywords : Gene Expression Regulation
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Naringin was found to upregulate the FoxM1 transcription factor in diabetic animals, which influenced the proliferation and functional status of beta cells.May 07, 2019

Pubmed Data : Cells Tissues Organs. 2019 May 8:1-12. Epub 2019 May 8. PMID: 31067533
Article Published Date : May 07, 2019
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : MicroRNA modulator, Pancreato Protective Agents
[+]

Naringin was observed to have a protective effect on 5-FU-induced liver and kidney damage.Mar 31, 2018

Pubmed Data : Iran J Basic Med Sci. 2018 Apr ;21(4):404-410. PMID: 29796225
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Chemotherapy-Induced Toxicity: 5-fluorouracil
Pharmacological Actions : Chemoprotective Agents, Hepatoprotective, Renoprotective
[+]

Naringin's protective effect in inflammation may be beneficial for the treatment of sepsis.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(10):e0164186. Epub 2016 Oct 7. PMID: 27716835
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Navel orange peel hydroethanolic extract, naringin and naringenin have anti-diabetic potentials in type 2 diabetic rats.Sep 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Oct ;94:197-205. Epub 2017 Jul 28. PMID: 28759757
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin, Citrus Peel , Naringenin
Diseases : Alcohol Toxicity , Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
Additional Keywords : Plant Extracts
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Possible neuroprotective mechanisms of action involved in the neurobehavioral property of naringin in miceDec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:536-546. Epub 2018 Nov 3. PMID: 30399589
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Anxiety, Depression, Memory Disorders
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Propolis and single flavonoids, caffeic acid, chrysin and naringin are radioprotective against gamma-irradiation.Jan 01, 2008

Pubmed Data : Biol Pharm Bull. 2008 Jan;31(1):167-72. PMID: 18175964
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Bee Propolis, Caffeic Acid, Chrysin, Citrus naringin
Diseases : DNA damage, Radiation Induced Illness
Pharmacological Actions : Radioprotective
[+]

Protective effect of naringin on DSS-induced ulcerative colitis in mice.Nov 25, 2018

Pubmed Data : J Agric Food Chem. 2018 Nov 26. Epub 2018 Nov 26. PMID: 30472831
Article Published Date : Nov 25, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

The effects of naringin on different cyclophosphamide-induced organ toxicities.Jul 09, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Jul 10. Epub 2019 Jul 10. PMID: 31292874
Article Published Date : Jul 09, 2019
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions : Chemoprotective Agents
Problem Substances : Cyclophosphamide
[+]

The navel orange peel hydroethanolic extract, naringin, and naringenin induced potential hepatopreventive effects.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:2745352. Epub 2019 Mar 26. PMID: 31049130
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin, Citrus Peel , Naringenin , Orange
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
[+]

The renoprotective effects of naringin on renal ischemia/reperfusion injury.Feb 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Feb 16 ;112:108568. Epub 2019 Feb 16. PMID: 30780111
Article Published Date : Feb 15, 2019
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Ischemia
Pharmacological Actions : Anti-Apoptotic, Antioxidants, MicroRNA modulator, Renoprotective
[+]

These findings suggest that naringin possesses anti-depressant- and anxiolytic-like activities as well as memory enhancing effect in mice.Jul 31, 2018

Pubmed Data : Drug Res (Stuttg). 2018 Aug ;68(8):465-474. Epub 2018 Mar 12. PMID: 29529676
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Anxiety, Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

This study demonstrated that naringin ameliorates diabetic nephropathy.Jun 04, 2017

Pubmed Data : Eur J Pharmacol. 2017 Jun 5 ;804:1-6. Epub 2017 Apr 7. PMID: 28395989
Article Published Date : Jun 04, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Apoptotic, Enzyme Inhibitors, Renoprotective
[+]

Urea cycle pathway targeted therapeutic action of naringin against ammonium chloride induced hyperammonemic rats.Sep 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Oct ;94:1028-1037. Epub 2017 Aug 12. PMID: 28813782
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Hyperammonemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Citrus bioactive compounds improve bone quality and plasma antioxidant activity in orchidectomized rats.Jun 01, 2009

Pubmed Data : Phytomedicine. 2009 Jun;16(6-7):513-20. Epub 2008 Oct 18. PMID: 18930642
Article Published Date : Jun 01, 2009
Study Type : Commentary
Additional Links
Substances : Citrus naringin, Citrus Peel
Diseases : Osteoporosis: Male
[+]

Induction of human hepatocellular carcinoma HepG2 cell apoptosis by naringin.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2016 ;17(7):3289-94. PMID: 27509965
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Liver Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Naringenin increases the chemosensitization of cancer cells. Jan 01, 2009

Pubmed Data : Z Naturforsch C. 2009 Jan-Feb;64(1-2):109-16. PMID: 19323275
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Cancers: Multi-Drug Resistant
Additional Keywords : Drug-Plant-Vitamin Synergies
[+]

Naringenin, and related compounds, have anti-androgenic properties. Sep 01, 2003

Pubmed Data : Planta Med. 2003 Sep;69(9):856-8. PMID: 14598215
Article Published Date : Sep 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin, Naringenin
Diseases : Androgen-Induced Diseases
Pharmacological Actions : Anti-Androgen
[+]

Naringin abates adverse effects of cadmium-mediated hepatotoxicity.Jul 31, 2017

Pubmed Data : J Biochem Mol Toxicol. 2017 Aug ;31(8). Epub 2017 Apr 19. PMID: 28422390
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Cadmium Poisoning , Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective, Nrf2 activation
Problem Substances : Cadmium
[+]

Naringin acts as a chemosensitizer which synergistically strengthens the cytotoxic effect of paclitaxel in prostate cancer cells.Nov 30, 2018

Pubmed Data : Prostate Int. 2018 Dec ;6(4):126-135. Epub 2017 Nov 28. PMID: 30505814
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Prostate Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Paclitaxel
[+]

Naringin ameliorates the high glucose-induced rat mesangial cell inflammatory.Jun 21, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Jun 22 ;18(1):192. Epub 2018 Jun 22. PMID: 29929501
Article Published Date : Jun 21, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Naringin can upregulate the expression of miR-19b mRNA and induce HepG2 cell apoptosis.Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Aug ;14(2):1455-1459. Epub 2017 May 29. PMID: 28789364
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, MicroRNA modulator
[+]

Naringin dose dependently decreased the total chromosome aberrations frequency induced by bleomycin.May 04, 2015

Pubmed Data : Drug Chem Toxicol. 2015 May 5:1-5. Epub 2015 May 5. PMID: 25941869
Article Published Date : May 04, 2015
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Chemotherapy-Induced Toxicity: Bleomycin, DNA damage
Pharmacological Actions : Genoprotective
Additional Keywords : Dose Response
[+]

Naringin enhances osteogenic differentiation through the activation of ERK signaling in human bone marrow mesenchymal stem cells.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2017 Apr ;20(4):408-414. PMID: 28804610
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
Additional Keywords : Mesenchymal Stem Cells
[+]

Naringin inhibits lipopolysaccharide-induced activation of microglia cells.Jun 29, 2019

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2019 Jun 30 ;65(5):38-42. Epub 2019 Jun 30. PMID: 31304904
Article Published Date : Jun 29, 2019
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Naringin is an antioxidant that appears to be efficacious in alleviating metabolic syndrome.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:9752826. Epub 2019 Feb 3. PMID: 30854019
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Citrus naringin
Diseases : Metabolic Syndrome X
Pharmacological Actions : Antihypertensive Agents, Antioxidants, Hypoglycemic Agents, Hypolipidemic
[+]

naringin is an effective compound for promoting bone repair and preventing bone loss.Apr 30, 2019

Pubmed Data : Chem Biol Interact. 2019 May 1 ;304:97-105. Epub 2019 Mar 14. PMID: 30878453
Article Published Date : Apr 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Osteonecrosis
Pharmacological Actions : Anti-Apoptotic, Osteoprotective
[+]

Naringin may possess novel therapeutic potential for protection against LPS-induced myocardial dysfunction.Jul 30, 2019

Pubmed Data : Int Immunopharmacol. 2019 Jul 31 ;75:105782. Epub 2019 Jul 31. PMID: 31376623
Article Published Date : Jul 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Naringin possesses significant antimicrobial properties on peridontal pathogens.Mar 01, 2008

Pubmed Data : Phytother Res. 2008 Mar;22(3):401-6. PMID: 18167053
Article Published Date : Mar 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Gingivitis, Peridontal Infection
Pharmacological Actions : Anti-Bacterial Agents
[+]

Naringin prevents UVB-mediated inflammation and oxidative damage in NIH-3T3 cells.Dec 03, 2018

Pubmed Data : J Biochem Mol Toxicol. 2018 Dec 4:e22263. Epub 2018 Dec 4. PMID: 30512238
Article Published Date : Dec 03, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Photoprotective
[+]

Naringin protects against HIV-1 protease inhibitors-induced pancreatic β-cell dysfunction and apoptosis.Jan 04, 2016

Pubmed Data : Mol Cell Endocrinol. 2016 12 5 ;437:1-10. Epub 2016 Aug 2. PMID: 27496642
Article Published Date : Jan 04, 2016
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : HIV Drug-Induced Toxicity , Lipid Peroxidation
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Pancreato Protective Agents
[+]

Naringin protects pancreatic β-cells against oxidative stress-induced apoptosis. Feb 28, 2018

Pubmed Data : Mol Nutr Food Res. 2018 Mar ;62(5). Epub 2018 Feb 5. PMID: 29314619
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Diabetes: Oxidative Stress, Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Pancreato Protective Agents
[+]

Naringin protects ultraviolet B-induced skin damage by regulating p38 MAPK signal pathway.Apr 30, 2016

Pubmed Data : J Dermatol Sci. 2016 May ;82(2):106-14. Epub 2015 Dec 22. PMID: 26908354
Article Published Date : Apr 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Inflammation, Ultraviolet Radiation Induced Damage
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Anti-Apoptotic, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Naringin suppresses the growth and motility of hypertrophic scar fibroblasts.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:1291-1298. Epub 2018 Jun 23. PMID: 30021366
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Scars, Wound Healing
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Naringin targets Zeb1 to suppress osteosarcoma cell proliferation and metastasis.Dec 21, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2018 Dec 22 ;10(12):4141-4151. PMID: 30580326
Article Published Date : Dec 21, 2018
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Osteosarcoma
Pharmacological Actions : Anti-metastatic, Antiproliferative
[+]

The impact of some natural phenolic compounds on carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes.Nov 30, 2017

Pubmed Data : J Biochem Mol Toxicol. 2017 Dec ;31(12). Epub 2017 Sep 13. PMID: 28902458
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Chrysin, Citrus naringin, Ginger, Hesperidin, Polyphenols
Diseases : Hypoglycemia
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

The mechanism of Naringin-enhanced remyelination after spinal cord injury.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2017 Mar ;12(3):470-477. PMID: 28469664
Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Spinal Cord Injuries
Additional Keywords : Nerve Regeneration
[+]

Therapeutic potential of naringin in neurological disorders.Jun 25, 2019

Pubmed Data : Food Chem Toxicol. 2019 Jun 26 ;132:110646. Epub 2019 Jun 26. PMID: 31252025
Article Published Date : Jun 25, 2019
Study Type : Review
Additional Links
Substances : Citrus naringin
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
[+]

These results suggest a novel mechanism of naringin in the suppression of cancer cell growth through the alteration of glycolipids.Apr 18, 2016

Pubmed Data : Eur J Pharmacol. 2016 Apr 19. Epub 2016 Apr 19. PMID: 27105818
Article Published Date : Apr 18, 2016
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Carcinoma: Non-Small-Cell Lung, Cervical Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

These results suggest that naringin can be utilized as a potential treatment of neurodegenerative disorders.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2017 Apr ;39(4):819-830. Epub 2017 Feb 22. PMID: 28260042
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Lipopolysaccharide-Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nrf2 activation
[+]

This review shows the enhancing effects of bioenhancers of drugs, nutrients and vitamins in animals and humans.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2012 ;2012:637953. Epub 2012 Sep 17. PMID: 23028251
Article Published Date : Dec 31, 2011
Study Type : Review
Additional Links
Substances : Allicin, Aloe Vera, Capsaicin, Citrus naringin, Curcumin, Genistein, Glycyrrhizin, Piperine, Quercetin
Additional Keywords : Drug Interaction, Natural Substance/Drug Synergy, Supplementation

Copyright: lightwise / 123RF Stock Photo

Citrus naringin Related Articles

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Researchers from China's State Agriculture Ministry and Zhejiang University have determined that two ingredients commonly found in many citrus fruits, naringin and neohesperidin, will effectively reduce blood sugar.
Citrus Fruits Fight Ulcers, Stomach Cancer
Written by Case Adams, Naturopath
Multiple studies have now concluded that eating citrus fruits will help ulcers and reduce the risk of stomach cancer.

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