Delta-tetrahydrocannabinol THC - Page 2 | GreenMedInfo

Name	AC	CK
Multiple Sclerosis	43	313
Epilepsy	34	158
Neuropathic Pain	14	119
Inflammation	42	86
Tourette Syndrome	8	75
Cancers: All	38	63
Inflammatory Bowel Diseases	13	59
Pain	8	57
Epilepsy: Childhood	6	56
Anxiety	13	53
Morphine Tolerance/Dependence	6	50
Seizures	8	42
Glioma	19	40
Huntington Disease	10	40
Opioid Tolerance/Dependence	1	40
Stroke	2	40
Stroke: Attenuation/Recovery	6	39
Chronic Pain	9	38
Glioblastoma Multiforme	10	38
Parkinson's Disease	13	36
Spinal Cord Injuries	4	34
Dravet syndrome	5	33
Muscle Spasticity	3	32
Diabetes Mellitus: Type 2	7	31
Neurodegenerative Diseases	21	31
Brachial Plexus Neuropathies	2	30
Anxiety Disorders	8	29
Breast Cancer	18	29
Brain Inflammation	17	27
Oxidative Stress	13	27
Sleep Disorders	5	27
Alzheimer's Disease	18	26
Amyotrophic lateral sclerosis (ALS)	4	24
Depression	11	24
Schizophrenia	11	24
Insomnia	3	23
Obsessive-Compulsive Disorder	4	23
Bladder Dysfunction	2	22
Lung Cancer	12	22
Marijuana Addiction/Withdrawal	3	22
Memory Disorders	5	22
Post-Traumatic Stress Disorders (PTSD)	8	22
Autism Spectrum Disorders	3	21
Cancer Metastasis	11	21
Hypoglycemia	1	20
Overactive Bladder	1	20
Peripheral Nerve Diseases	1	20
Dementia	5	19
Lipopolysaccharide-Induced Toxicity	10	19
Stroke: Ischemic	4	19
Brain Cancer	4	18
Colitis	7	17
HIV Infections	5	17
Diabetic Neuropathies	3	16
Glioblastoma	8	16
Hyperalgesia	6	16
Nonalcoholic fatty liver disease (NAFLD)	3	16
Acne	2	15
Brain Ischemia	7	15
Ulcerative Colitis	2	15
Brain: Microglial Activation	6	14
Astrocytoma	4	13
Brain Damage: Hypoxic Ischemic Insult	6	13
Chemotherapy-Induced Toxicity: Cisplatin	4	13
Psychoses	4	13
Brain Injury: Traumatic	2	12
Epileptic Seizures	2	12
Hypertension	2	12
Prostate Cancer	10	12
Amyotrophic Lateral Sclerosis	7	11
Colon Cancer	7	11
Endocannabinoid Disorders	2	11
Lennox-Gastaut Syndrome	2	11
Skin Cancer	5	11
Anorexia: Dementia-Associated	1	10
Attention Deficit Hyperactivity Disorder	1	10
Cardiovascular Diseases	4	10
Cerebral Ischemia	4	10
Cognitive Decline/Dysfunction	5	10
Crack Addiction/Withdrawal	1	10
Delirium: Drug-Induced	1	10
Dry Skin	1	10
Glaucoma	4	10
Impairment: Driving Related	1	10
Incontinence	1	10
Nausea: Pregnancy-Associated	1	10
Neurogenic Bladder	1	10
Neuropathic Pain: HIV-associated	1	10
Neuropathy: HIV associated	1	10
Obesity	5	10
Organ Transplantation: Kidney	1	10
Pancreatitis: Chronic	1	10
Phantom Limb	1	10
Quality of Life: Poor	1	10
Social Anxiety Disorder (SAD)	1	10
Stress	1	10
Sturge-Weber Syndrome	1	10
Tuberous Sclerosis	1	10
Vaccine-induced Toxicity	1	10
Breast Cancer: Triple Negative	6	9
Allodynia	4	8
Autoimmune Diseases	5	8
Endocannabinoid System	7	8
Melanoma	4	8
Middle Cerebral Artery Occlusion (MCAO)	4	8
Myocardial Infarction	3	8
Myocardial Ischemia	3	8
Traumatic Memory Formation	4	8
Colorectal Cancer	5	7
Diabetic Complications	4	7
Lymphoma	3	7
Aging: Brain	3	6
Astrocytoma: Grade IV	1	6
Emesis	1	6
Epidermolysis Bullosa	1	6
Vomiting	1	6
Acute Myeloid Leukemia	2	5
Alcoholic Liver Disease	1	5
Asthma	3	5
Brain: Oxidative Stress	2	5
Cachexia	3	5
Cancer: Pain	3	5
Chemotherapy and Radiation Toxicity	2	5
Chemotherapy-Induced Toxicity: Doxorubicin	3	5
Cholangiocarcinoma	1	5
Diabetes Mellitus: Type 1: Prevention	3	5
Drug Abuse	3	5
Gastrointestinal Inflammation	2	5
Gliomas	3	5
Leukemia	4	5
Neuroblastoma	2	5
Psychiatric Disorder: Conditioned Fear	3	5
Psychiatric Disorders	4	5
Alcohol Toxicity	2	4
Arteriosclerosis	1	4
Bladder Cancer	3	4
Brain Damage	3	4
Chemotherapy-Induced Nausea	3	4
Chemotherapy-Induced Toxicity: Oxaliplatin	1	4
Chemotherapy-Induced Toxicity: Paclitaxel	1	4
Chemotherapy-Induced Toxicity: Vincristine	1	4
Colon Cancer: Prevention	2	4
Dermatitis	1	4
Diabetes Mellitus: Type 1	2	4
Diabetes: Cataract	2	4
Endothelial Dysfunction	2	4
Endotoxemia	2	4
Eye Damage	1	4
High Fat Diet	2	4
Hypersensitivity	2	4
Iron Overload	2	4
Liver Cancer	3	4
Metabolic Syndrome X	1	4
Osteoarthritis	3	4
Pancreatic Cancer	4	4
Psychotic Disorders	3	4
Rhabdomyosarcoma	1	4
Thyroid Cancer	3	4
Acute T cell Leukemias	2	3
Aging	2	3
Allergic Airway Diseases	2	3
Arthritis	2	3
Attention Deficit Disorder with Hyperactivity	1	3
Autism	2	3
Bipolar Disorder	1	3
Drug Addiction	2	3
Encephalomyelitis	2	3
Endometrial Cancer	1	3
Epilepsy: Infant	1	3
Epilepsy: Malignant Migrating Partial Seizures	1	3
Febrile Seizures	1	3
Fibrosis	2	3
Immune Disorders	2	3
Multiple Myeloma	2	3
Psoriasis	3	3
Tremor	2	3
Acute lymphoblastic leukemia (ALL)	1	2
Alcohol Withdrawal	1	2
Amphetamine Addiction/Withdrawal	1	2
Animal Diseases: Simian Immunodeficiency Virus (SIV)	1	2
Appetite Disorders: Loss/Lack of	1	2
Bone Fractures	1	2
Brain Edema	1	2
Breast Cancer: Lung Metastasis	1	2
Breast Cancer: Metastatic	1	2
Breast Cancer: Prevention	1	2
Cachexia: Cancer	2	2
Cachexia: Chemotherapy Induced	1	2
Carcinoma: Non-Small-Cell Lung	1	2
Cardiac Arrhythmias	1	2
Cardiomyopathy	1	2
Cerebral Hypoperfusion	1	2
Cocaine Toxicity	1	2
Cough	1	2
Degenerative Disk Disease	1	2
Depression	1	2
Depressive Disorder	1	2
Dermatitis: Contact	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Memory Problems	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Neuropathy	1	2
Diabetic Retinopathy	1	2
Drug-Induced Toxicity: Epilepsy Drugs	1	2
Epilepsy: Drug-Induced	1	2
Fatty Liver	1	2
Friedreich Ataxia	1	2
Fulminant Hepatic Failure	1	2
Gastrointestinal Diseases	1	2
Gastroschisis	1	2
Headache	2	2
Heart Attack	1	2
Hepatic Encephalopathy	1	2
Hepatitis C	2	2
Hypersensitivity: Type IV	1	2
Hypothermia	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Infant Neurological Development	1	2
Inflammation: Neutrophil-Mediated	1	2
Insulin Resistance	1	2
Interstitial Lung Diseases	1	2
Ischemia	1	2
Liver Damage	1	2
Liver Disease	1	2
Liver Failure: Acute	1	2
Liver Injury: Ischemia/reperfusion	1	2
Lung Inflammation	1	2
Malaria	1	2
Memory Disorders: Drug-Induced	1	2
Metabolic Diseases	1	2
Mitochondrial Dysfunction	1	2
Mood Disorders	1	2
Muscle Soreness	1	2
Myocarditis: Autoimmune	1	2
Neonatal Stroke	1	2
Neuralgia	1	2
Oral Cancer	1	2
Periodontitis	1	2
Prion Diseases	1	2
Sciatic Nerve Crush Injury	1	2
Sepsis	1	2
Spinal Cord Inflammation	1	2
Staphylococcus aureus infection	1	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	2
Tardive Dyskinesia	1	2
Traumatic Brain Injury	1	2
Urinary Bladder Diseases	1	2
Uveitis	1	2
AIDS	1	1
Acquired Immunodeficiency Syndrome	1	1
Alcohol Addiction	1	1
Anorexia	1	1
Appetite Disorders	1	1
Arthritis: Rheumatoid	1	1
Atherosclerosis	1	1
Bone Diseases	1	1
Bronchial Diseases	1	1
Cancers: Drug Resistant	1	1
Cancers: Multi-Drug Resistant	1	1
Candida Infection	1	1
Central Nervous System Diseases	1	1
Cervical Cancer	1	1
Cirrhosis	1	1
Clostridium Infections	1	1
Diabetes: Cognitive Dysfunction	1	1
Dystonia	1	1
Ebola Virus Infections	1	1
Gastric Cancer	1	1
Hepatitis	1	1
Hepatitis: Autoimmune	1	1
Herpes Simplex Virus Type 2	1	1
Herpes: Kaposi-Associated	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Influenza	1	1
Intestinal Permeability	1	1
Irritable Bowel Syndrome	1	1
Kaposi Disease	1	1
Kidney Cancer	1	1
Kidney Damage	1	1
Leishmaniasis	1	1
Leukemia: T-cell acute Lymphoblastic	1	1
Liver Fibrosis	1	1
Movement Disorders	1	1
Nausea: Chemotherapy-Induced	1	1
Oral Mucositis	1	1
Osteoporosis	1	1
Peripheral Neuropathies	1	1
Prostate: PSA Doubling	1	1
Pseudomonas aeruginosa	1	1
Rheumatoid Arthritis	1	1
Skin Diseases	1	1
Testicular Cancer	1	1
Tobacco Addiction/Withdrawal	1	1
Tumors	1	1
Ultraviolet Radiation Induced Damage	1	1

Name	AC	CK
Anti-Inflammatory Agents	108	283
Neuroprotective Agents	114	281
Anticonvulsants	39	217
Analgesics	39	205
Apoptotic	78	144
Antiproliferative	61	119
Anti-Anxiety Agents	18	73
Immunomodulatory	23	49
Tumor Necrosis Factor (TNF) Alpha Inhibitor	23	48
Antioxidants	26	47
Anti-metastatic	21	44
Angiogenesis Inhibitors	14	43
Antineoplastic Agents	26	38
Antidepressive Agents	12	37
Vasodilator Agents	5	31
Antinoceceptive	9	29
Hypoglycemic Agents	3	24
Anti-Apoptotic	12	23
Cyclooxygenase 2 Inhibitors	7	23
Antispasmodic	2	22
Vascular Endothelial Growth Factor Inhibitors	3	22
Immunosuppressive Agents	8	21
Chemotherapeutic	11	18
Anti-Tumor	9	17
Autophagy Up-regulation	9	17
Cardioprotective	8	17
NF-kappaB Inhibitor	9	16
Antihypertensive Agents	3	15
Cell cycle arrest	9	15
Chemoprotective Agents	5	15
Hepatoprotective	7	15
Interleukin-6 Downregulation	7	14
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	12
Neurogenesis	6	12
Antipsychotic Agents	7	11
Anxiolytic	2	11
Interferon Gamma Reducer	5	11
Interleukin-1 beta downregulation	6	11
Anticarcinogenic Agents	7	10
Chemopreventive	6	10
GABA Modulators	1	10
Superoxide Dismutase Up-regulation	4	10
Enzyme Inhibitors	3	9
Brain-derived neurotrophic factor modulator	4	8
Chemosensitizer	5	8
MicroRNA modulator	5	8
Nitric Oxide Inhibitor	3	8
Cannabinoid Receptor Antagonist/Inverse Agonist	3	7
P38 Mitogen-Activated Protein Kinase Modulator	2	7
Anti-Angiogenic	6	6
Vascular Cell Adhesion Molecule-1 Inhibitor	2	6
Appetite Stimulants	3	5
Hypolipidemic	1	5
Immunomodulatory: Th17 downregulation	3	5
Radiosensitizer	2	5
Anti-atherogenic	1	4
Caspase-3 Activation	3	4
Gastrointestinal Agents	3	4
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	1	4
Interleukin-10 downregulation	2	4
Interleukin-17 downregulation	3	4
Interleukin-4 downregulation	2	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	4
Osteoprotective	3	4
Prostaglandin PGE2 downregulation	2	4
Vascular Endothelial Growth Factor A Inhibitor	2	4
Vascular Endothelial Growth Factor Regulator	2	4
Cytotoxic	2	3
Gastroprotective	2	3
Interleukin-8 downregulation	2	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Neuritogenic	2	3
Renoprotective	2	3
Sedative effects	1	3
Vanilloid Receptor-1 Modulator	1	3
Aldose reductase inhibitor	1	2
Anti-Androgen	1	2
Anti-Bacterial Agents	2	2
Anti-Fibrotic	2	2
Calcium Channel Blockers	1	2
Catalase Up-Regulation	1	2
Cyclooxygenase Inhibitors	1	2
Enzyme Activators	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Glycine Agents	1	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	2
Immunomodulatory: T-Cell down-regulation	1	2
Interleukin-10 upregulation	1	2
Interleukin-12 downregulation	1	2
Interleukin-2 Downregulation	1	2
Interleukin-5 downregulation	1	2
Intracellular adhesion molecule-1 (ICAM-1)	1	2
Malondialdehyde Down-regulation	1	2
Neuroplasticity enhancement	1	2
Pancreato Protective Agents	1	2
Prophylactic Agents	1	2
Redox Modulator	1	2
Topoisomerase II Inhibitor	2	2
interleukin-13 down-regulation	1	2
Acetylcholinesterase Inhibitor	1	1
Anti-Cachexic Agents	1	1
Anti-Proliferative	1	1
Anti-Psychotic	1	1
Antifungal Agents	1	1
Antiviral Agents	1	1
Caspase-8 activation	1	1
Caspase-9 Activation	1	1
Cyclooxygenase 1 Inhibitor	1	1
Interleukin-2 upregulation	1	1
NADPH Oxidase Inhibitors	1	1
Neuroimmunomodulation	1	1
Nrf2 activation	1	1
Paraptosis	1	1
Photoprotective	1	1
Transient receptor potential vanilloid type-2 activation	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1
apoptosis	1	1

Additional Keywords : Endocannabinoid System, Plant Extracts

[+]

Cannabinoids can enhance the regenerative capacity of two major sources of stem cells, adipose- and bone marrow-derived from human and porcine donors.Dec 20, 2020

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Pubmed Data : Cell Biochem Funct. 2020 Dec 21. Epub 2020 Dec 21. PMID: 33349985

Article Published Date : Dec 20, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Huntingtons Dis. 2018 Mar 16. Epub 2018 Mar 16. PMID: 29562549

Article Published Date : Mar 15, 2018

Study Type : Review

Additional Links

Substances : Cannabinoids

Diseases : Huntington Disease

Pharmacological Actions : Neuroprotective Agents

[+]

Click here to read the entire abstract

Pubmed Data : J Neuroimmunol. 2002 Dec ;133(1-2):124-31. PMID: 12446015

Article Published Date : Nov 30, 2002

Study Type : In Vitro Study

Additional Links

Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Immune Dysregulation: TH1/TH2 imbalance

Pharmacological Actions : Immunomodulatory

Additional Keywords : Cannabinoid Receptors

[+]

Cannabinoids have therapeutic potential in central nervous system disease. Jan 13, 2011

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Pubmed Data : Eur J Pharmacol. 2011 Jan 13. Epub 2011 Jan 13. PMID: 12617697

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Pubmed Data : Curr Alzheimer Res. 2016 May 2. Epub 2016 May 2. PMID: 27137221

Article Published Date : May 01, 2016

Study Type : Review

Additional Links

Substances : Cannabinoids

Diseases : Alzheimer's Disease

[+]

Cannabinoids may therapeutic value in neurodegenerative conditions and cancer.Jan 01, 2001

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Pubmed Data : J Mol Med. 2001;78(11):613-25. PMID: 11269508

Article Published Date : Jan 01, 2001

Study Type : Review

Additional Links

Substances : Cannabinoids

Diseases : Cancers: All, Neurodegenerative Diseases

Pharmacological Actions : Antiproliferative , Apoptotic, Neuroprotective Agents

[+]

Additional Keywords : Drug: Paclitaxel, Drug Synergy

[+]

Cannabinoids: Potential role in inflammatory and neoplastic skin diseases.Dec 11, 2018

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Pubmed Data : Am J Clin Dermatol. 2018 Dec 12. Epub 2018 Dec 12. PMID: 30542832

Article Published Date : Dec 11, 2018

Study Type : Review

Additional Links

Substances : Cannabinoids

Diseases : Inflammation, Skin Diseases

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Cannabis and cannabinoids can protect the gastric mucosa against noxious challenge.Apr 30, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asian Pac J Trop Med. 2016 May ;9(5):413-9. Epub 2016 Apr 15. PMID: 27261847

Article Published Date : Apr 30, 2016

Study Type : Review

Click here to read the entire abstract

Pubmed Data : Med Clin North Am. 2020 May ;104(3):471-489. PMID: 32312410

Article Published Date : Apr 30, 2020

Study Type : Review

Additional Links

Substances : Cannabinoids

Diseases : Alzheimer's Disease, Cachexia: Cancer, Cancer: Pain , Chronic Pain, Dementia

Pharmacological Actions : Analgesics

[+]

Cannabis has potential therapeutic value in the treatment of amyotrophic lateral sclerosis.Aug 01, 2010

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Pubmed Data : Am J Hosp Palliat Care. 2010 Aug;27(5):347-56. Epub 2010 May 3. PMID: 20439484

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Pubmed Data : J Am Psychiatr Nurses Assoc. 2020 Jun 6:1078390320929410. Epub 2020 Jun 6. PMID: 32508204

Article Published Date : Jun 05, 2020

Study Type : Review

Additional Links

Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)

Diseases : Epilepsy, Neurologic Disorders, Psychiatric Disorders

Pharmacological Actions : Neuroprotective Agents

[+]

CBD and THC vary in their effects on the anti-inflammatory pathways, including the NF-kappaB and IFNbeta-dependent pathways.Jan 14, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Biol Chem. 2010 Jan 15 ;285(3):1616-26. Epub 2009 Nov 12. PMID: 19910459

Article Published Date : Jan 14, 2010

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor

[+]

CBD caused concentration-related inhibition of glioma cell migration.Mar 31, 2005

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Int J Infect Dis. 2016 Sep 26 ;52:74-76. Epub 2016 Aug 26. PMID: 27686726

Article Published Date : Sep 25, 2016

Study Type : Commentary

Additional Links

Substances : Cannabidiol

Diseases : Ebola Virus Infections

[+]

CBD induced oxidative stress in HT-29 colorectal carcinoma cells.Jul 31, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2020 Aug 1 ;21(15). Epub 2020 Aug 1. PMID: 32752303

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Pubmed Data : CNS Neurosci Ther. 2009 ;15(1):65-75. PMID: 19228180

Article Published Date : Dec 31, 2008

Study Type : Review

Additional Links

Substances : Cannabidiol

Diseases : Alzheimer's Disease, Huntington Disease, Multiple Sclerosis, Neurodegenerative Diseases

Pharmacological Actions : Neuroprotective Agents

[+]

CBD might be an improvement over other available drugs used for treating the fear-related symptoms of phobias.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2016 ;7:454. Epub 2016 Nov 24. PMID: 27932983

Article Published Date : Dec 31, 2015

Study Type : Review

Additional Links

Substances : Cannabidiol

Diseases : Anxiety, Post-Traumatic Stress Disorders (PTSD), Psychiatric Disorder: Conditioned Fear

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Benzodiazepines

[+]

CBD reverts the mesenchymal invasive phenotype of breast cancer cells induced by the inflammatory cytokine IL-1β.Mar 30, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2020 Mar 31 ;21(7). Epub 2020 Mar 31. PMID: 32244518

Article Published Date : Mar 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Breast Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic

[+]

CBD suppresses pro-inflammatory signalling and may be a potential new candidate for Alzheimer's disease therapy.Sep 30, 2017

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Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2017 Oct 1 ;49(10):853-866. PMID: 28981597

Article Published Date : Sep 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Alzheimer's Disease, Brain Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Wnt/β-catenin signaling pathway modulation

[+]

CBD treatment may ameliorate experimental autoimmune encephalomyelitis through induction of immunosuppressive myeloid-derived suppressor cells.Dec 31, 2017

Pubmed Data : Int J Mol Sci. 2019 Sep 26 ;20(19). Epub 2019 Sep 26. PMID: 31561450

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2015 Nov ;35(11):5827-37. PMID: 26504004

Article Published Date : Oct 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Glioma

Pharmacological Actions : Cytotoxic

[+]

High concentrations of cannabinoids are preferable for efficacious treatment of malignant astrocytomas.Dec 31, 2009

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Pubmed Data : PLoS One. 2010 ;5(1):e8702. Epub 2010 Jan 14. PMID: 20090845

Article Published Date : Dec 31, 2009

Study Type : In Vitro Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Astrocytoma, Brain Cancer

Pharmacological Actions : Apoptotic

[+]

In the current study we demonstrated that cannabidiol can induce apoptosis in murine as well as human leukemia cells.Aug 31, 2006

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Melatonin and cannabinoids: mitochondrial-targeted molecules that may reduce inflammaging in neurodegenerative diseases.Mar 09, 2020

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Pubmed Data : Histol Histopathol. 2020 Mar 10:18212. Epub 2020 Mar 10. PMID: 32154907

Article Published Date : Mar 09, 2020

Study Type : Review

Additional Links

Substances : Cannabinoids , Melatonin

Diseases : Alzheimer's Disease, Brain Inflammation , Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Molecular targets of cannabidiol in experimental models of neurological disease. Nov 06, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Chem Res Toxicol. 2018 Feb 19 ;31(2):137-144. Epub 2018 Jan 8. PMID: 29272108

Article Published Date : Feb 18, 2018

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Cancers: All

Pharmacological Actions : Topoisomerase II Inhibitor

[+]

Phytocannabinoids produce anticonvulsant effects through the endocannabinoid system, with few adverse effects.Mar 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FEBS Lett. 2005 Sep 12 ;579(22):5084-8. PMID: 16139274

Article Published Date : Sep 11, 2005

Study Type : In Vitro Study

Additional Links

Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Leukemia

Pharmacological Actions : Apoptotic, P38 Mitogen-Activated Protein Kinase Modulator

[+]

Results thus show that THC-induced apoptosis in glioma C6.9 cells may rely on a CBI receptor-independent stimulation of sphingomyelin breakdown.Sep 24, 1998

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Pubmed Data : FEBS Lett. 1998 Sep 25 ;436(1):6-10. PMID: 9771884

Article Published Date : Sep 24, 1998

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Pubmed Data : FASEB J. 2016 Jul 19. Epub 2016 Jul 19. PMID: 27435265

Article Published Date : Jul 18, 2016

Study Type : Review

Additional Links

Substances : Cannabinoids

Diseases : Fibrosis, Inflammation

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents

[+]

Several components of the endocannabinoid system have therapeutic potential in cirrhosis.Jun 08, 2018

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Pubmed Data : Medicines (Basel). 2018 Jun 9 ;5(2). Epub 2018 Jun 9. PMID: 29890719

Pubmed Data : Expert Opin Ther Targets. 2016 May 11:1-17. Epub 2016 May 11. PMID: 27070944

Article Published Date : May 10, 2016

Study Type : Review

Additional Links

Substances : Cannabinoids , Endocannabinoids

Diseases : Cancer Metastasis, Cancers: All

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Sustained ceramide accumulation in tumor cells mediates cannabinoid induced apoptosis.Aug 18, 2005

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Pubmed Data : Life Sci. 2005 Aug 19 ;77(14):1723-31. PMID: 15958274

Article Published Date : Aug 18, 2005

Study Type : Review

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Substances : Cannabinoids

Pharmacological Actions : Apoptotic

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Systematic review of the potential role of cannabinoids as antiproliferative agents for urological cancers.Feb 28, 2017

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Pubmed Data : Can Urol Assoc J. 2017 Mar-Apr;11(3-4):E138-E142. Epub 2017 Apr 11. PMID: 28515817

Article Published Date : Feb 28, 2017

Study Type : Review

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Substances : Cannabinoids

Diseases : Bladder Cancer, Kidney Cancer, Prostate Cancer, Testicular Cancer

Pharmacological Actions : Antiproliferative

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Targeting calcium signaling in cancer therapy.Dec 31, 2016

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Pubmed Data : Drugs. 2017 Mar 14. Epub 2017 Mar 14. PMID: 28293911

Article Published Date : Mar 13, 2017

Study Type : Review

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Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)

Diseases : Multiple Sclerosis

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The ability of cannabidiol to behave as a CB2 receptor inverse agonist may contribute to its documented anti-inflammatory properties.Feb 28, 2007

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Pubmed Data : Pain Res Manag. 2001 ;6(2):95-101. PMID: 11854771

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Pubmed Data : Curr Pharm Des. 2008;14(23):2306-16. PMID: 18781981

The literature suggests that the medicinal use of cannabis may have a therapeutic role for a multitude of diseases.May 31, 2015

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Pubmed Data : Headache. 2015 Jun ;55(6):885-916. Epub 2015 May 25. PMID: 26015168

Article Published Date : May 31, 2015

Study Type : Review

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Chronic Pain, Headache

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substance/Drug Synergy

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The present studies demonstrate that the enhancement of IL-2 secretion by CBN is mediated through a positive influence on the NF-AT signalling.Jan 31, 2002

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Pubmed Data : Front Pharmacol. 2019 ;10:627. Epub 2019 May 31. PMID: 31214036

Article Published Date : Dec 31, 2018

Study Type : Review

Additional Links

Substances : Cannabidiol

Diseases : Alcohol Toxicity

Pharmacological Actions : Hepatoprotective, Neuroprotective Agents

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There exists solid scientific evidence supporting that cannabinoids exhibit a remarkable anticancer activity in preclinical models of cancer.Jan 03, 2016

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Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 4 ;64:259-66. Epub 2015 Jun 10. PMID: 26071989

Article Published Date : Jan 03, 2016

Study Type : Review

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Cancers: All

Pharmacological Actions : Apoptotic, Autophagy Up-regulation

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Pubmed Data : Expert Rev Neurother. 2017 Sep 4:1-11. Epub 2017 Sep 4. PMID: 28845714

Article Published Date : Sep 03, 2017

Study Type : Review

Additional Links

Substances : Cannabidiol, Cannabidivarin, Cannabinoids

Diseases : Epilepsy

Pharmacological Actions : Anticonvulsants

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This review will center on mechanisms by which CBD, and other plant-derived cannabinoids inefficient at activating cannabinoid receptors, inhibit tumor cell viability, invasion, metastasis, angiogenesis.May 31, 2015

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Pubmed Data : J Neuroimmune Pharmacol. 2015 Jun ;10(2):255-67. Epub 2015 Apr 28. PMID: 25916739

Article Published Date : May 31, 2015

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Pubmed Data : Handb Exp Pharmacol. 2005(168):627-42. PMID: 16596790

Article Published Date : Dec 31, 2004

Study Type : Review

Additional Links

Substances : Cannabinoids

Diseases : Cancers: All, Neurodegenerative Diseases

Pharmacological Actions : Anti-Angiogenic, Antineoplastic Agents, Antiproliferative , Apoptotic, Neuroprotective Agents

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This reviews the evidence, efficacy and effectiveness of THC-CBD oromucosal spray in symptom management for patients with spasticity due to MS.Dec 31, 2015

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Pubmed Data : Pharmacol Res. 2016 Feb 1. Epub 2016 Feb 1. PMID: 26845349

Article Published Date : Jan 31, 2016

Study Type : Review

Additional Links

Substances : Cannabidiol

Diseases : Anxiety Disorders, Brain Damage, Brain Ischemia, Depression, Neurodegenerative Diseases, Psychiatric Disorders

Pharmacological Actions : Neuroprotective Agents

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TRPV2 activation could be a novel therapeutic strategy to enhance the uptake and efficacy of chemotherapy in TNBC patients.May 26, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 May 27. Epub 2016 May 27. PMID: 27248470

Article Published Date : May 26, 2016

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Transient receptor potential vanilloid type-2 activation

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin, Median Survival Time

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Unheated Cannabis sativa extracts have potential immuno-modulating properties. Mar 31, 2006

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Pubmed Data : Int Immunopharmacol. 2006 Apr ;6(4):656-65. Epub 2005 Nov 7. PMID: 16504929

Article Published Date : Mar 31, 2006

Study Type : In Vitro Study

Additional Links

Substances : Cannabis, Delta-tetrahydrocannabinol (THC)

Pharmacological Actions : Immunomodulatory, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

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View the Evidence: 742 Abstracts with Delta-tetrahydrocannabinol (THC) Research

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Cannabinoids are promising candidates for gastrointestinal and urinary diseases.Dec 31, 2014

Cannabinoids as anticancer therapeutic agents.Apr 30, 2020

Cannabinoids at non-psychoactive doses could be useful in chemotherapy-induced diarrhea.Feb 28, 2017

Cannabinoids can activate TRPA1, TRPV1 and TRPV2.Jul 31, 2011

Cannabinoids can enhance the regenerative capacity of two major sources of stem cells, adipose- and bone marrow-derived from human and porcine donors.Dec 20, 2020

Cannabinoids could be helpful for certain symptoms of inflammatory bowel diseases.Mar 31, 2017

Cannabinoids could be possible agents for treatment of psoriasis. Jan 31, 2017

Cannabinoids could be used for the inhibition of tumor growth in a clinical setting.Jan 14, 2008

Cannabinoids could confer neuroprotection against epilepsy.Dec 31, 2016

Cannabinoids exert anti-inflammatory, anti-proliferative, anti-invasive, anti-metastatic and pro-apoptotic effects in different cancer types.May 31, 2015

Cannabinoids for treatment of dystonia in Huntington's disease.Mar 15, 2018

Cannabinoids have a potential therapeutic value in the treatment of psoriasis.Feb 01, 2007

Cannabinoids have analgesic potential.Nov 01, 2009

Cannabinoids have cyclooxygenase inhibitory properties.Jan 01, 2011

Cannabinoids have neuroprotective properties. May 31, 2007

Cannabinoids have potent and efficacious modulatory effects on TRPA1and TRPM8 mediated intracellular Ca2 elevation.May 31, 2008

Cannabinoids have the potential to regulate the activation and balance of human Th1/Th2 cells by a CB2 receptor-dependent pathway.Nov 30, 2002

Cannabinoids have therapeutic potential in central nervous system disease. Jan 13, 2011

Cannabinoids in treatment-resistant epilepsy: A review.Feb 07, 2017

Cannabinoids inhibit glioma (brain cancer) cell growth in vitro. Mar 15, 2008

Cannabinoids inhibited pancreatic cancer.Oct 27, 2020

Cannabinoids may be an effective adjunct for the treatment of pancreatic cancer.Dec 31, 2018

Cannabinoids may be ideal candidates for the treatment of gliomas.Sep 01, 2004

Cannabinoids may be promising tools in combination therapy for breast and prostate cancers.Oct 31, 2016

Cannabinoids may have a role to play in arthritis prevention and treatment. Feb 28, 2006

Cannabinoids may have a therapeutic role in the treatment of autoimmune hepatitis. Jan 01, 2009

Cannabinoids may have potential anti-psoriatic activityMay 10, 2016

Cannabinoids may have therapeutic potential in the treatment of intestinal permeability.Jun 30, 2010

Cannabinoids may have therapeutic value in the treatment of movement disorders.Oct 01, 1999

Cannabinoids may have therapeutic value in the treatment of prostate cancer. Mar 01, 2005

Cannabinoids may have therapeutic value in treating neuroinflammation. Jan 01, 2011

Cannabinoids may provide a safer alternative treatment option for the management of agitation and aggression in AD.May 01, 2016

Cannabinoids may therapeutic value in neurodegenerative conditions and cancer.Jan 01, 2001

Cannabinoids might be a suitable treatment for rheumatoid arthritis.Apr 30, 2019

Cannabinoids modulate neuronal activity and cancer by CB1 and CB2 receptor-independent mechanisms.Dec 31, 2016

Cannabinoids possess attributes that have impact in both cancer pain and prostate cancer pathophysiology.Dec 31, 2011

Cannabinoids prevent proliferation and cause apoptosis via a combination of cannabinoid receptor-independent, cellular and molecular mechanisms.Dec 31, 2012

Cannabinoids reduce ErbB2-positive breast cancer cell progression. Jan 01, 2010

Cannabinoids reduce multidrug resistance in a human T lymphoblastoid leukaemia cell line.Apr 14, 2006

Cannabinoids seem to be selective antitumoral compounds, killing glioma cells but not non transformed cells.Jul 31, 2007

Cannabinoids showed potent activity against a variety of methicillin-resistant Staphylococcus aureus (MRSA) strains.Jul 31, 2008

Cannabinoids significantly inhibit proliferation and incrases death of human gliobastoma multiforme cells without significant impact on human primary glial cultures. Aug 01, 2005

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration.Oct 17, 2016

Cannabinoids that activate the CB2R inhibit the ECM adhesion process, thus has potential to serve as a therapeutic agent for ablating neuroinflammation associated with HIV.May 27, 2014

Cannabinoids were shown to be of potential use for therapeutic approaches of glioblastoma.May 04, 2016

Cannabinoids work synergistically with paclitaxel in gastric cancer cell lines.Jul 01, 2009

Cannabinoids: Potential role in inflammatory and neoplastic skin diseases.Dec 11, 2018

Cannabis and cannabinoids can protect the gastric mucosa against noxious challenge.Apr 30, 2016

Cannabis and the cannabinoids in addition to their potential applications in the treatment of a number of serious illnesses.Dec 31, 2016

Cannabis could be an effective ocular hypotensive agent.Feb 29, 2016

Cannabis for symptom management in older adults.Apr 30, 2020

Cannabis has potential therapeutic value in the treatment of amyotrophic lateral sclerosis.Aug 01, 2010

Cannabis may have a therapeutic role for appetite disorders.Jan 07, 2011

Cannabis may have a therapeutic role to play in reducing inflammation and over-active immune cells in autoimmune diseases. May 18, 2009

Cannabis roots: A traditional therapy with future potential for treating inflammation and pain.Dec 31, 2016

Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury.Jul 31, 2019

Cannabis sativa: The plant of the thousand and one molecules.Dec 31, 2015

Cannabis-based medications may be useful for treating refractory chemotherapy-induced nausea and vomiting. Nov 11, 2015

CB1 receptor immunoreactivity was significantly lower while CB2 receptor immunoreactivity was significantly greater in the membranes of glioblastoma multiforme and astrocytoma.Apr 30, 2010

CB2 receptor activation signals apoptosis via a ceramide-dependent stimulation of the mitochondrial intrinsic pathway.Jun 30, 2006

CBD and CBD and THC combinations have potential to provide safe, effective therapy for several psychiatric and neurologic conditions and diseases.Jun 05, 2020

CBD and THC vary in their effects on the anti-inflammatory pathways, including the NF-kappaB and IFNbeta-dependent pathways.Jan 14, 2010

CBD caused concentration-related inhibition of glioma cell migration.Mar 31, 2005

CBD could preferentially induce apoptosis and attenuate the proliferation of KSHV-infected HMVECs.Jun 30, 2012

CBD differentially regulated basal pro-inflammatory response and attenuated both LPS-induced cytokine release and NF-κB activity in monocytes.Aug 18, 2019

CBD has a neurorestorative potential independent of NGF that might contribute to its neuroprotection against neurotoxins relevant to Parkinson's disease.Nov 06, 2015

CBD has a promising role as alternative therapy in the management of anxiety disorders.Dec 18, 2019

CBD has been shown to decrease proinflammatory functions and signaling in astrocytes.Jul 30, 2017

CBD has pharmacological effects that may significantly improve the mental and somatic health of patients suffering from post Ebola sequelae.Sep 25, 2016

CBD induced oxidative stress in HT-29 colorectal carcinoma cells.Jul 31, 2020

CBD inhibitory effects on the NLRP3 inflammasome may contribute to the overall anti-inflammatory effects reported for this phytocannabinoid.May 05, 2020

CBD loaded microparticles as a potential formulation to improve paclitaxel and doxorubicin-based chemotherapy in breast cancer.Jan 24, 2020

Delta-tetrahydrocannabinol (THC)

View the Evidence:
742 Abstracts with Delta-tetrahydrocannabinol (THC) Research