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Flavonoids
Views 6069
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Abstracts
Focused Research Topics
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Click any topic below to filter + focus research
295 Diseases Researched for Flavonoids
Name
AC
CK
Focus
Hypertension
15
128
Cardiovascular Diseases
17
108
Oxidative Stress
49
93
Inflammation
33
84
Colorectal Cancer
12
83
Endothelial Dysfunction
14
79
Cholesterol: Oxidation
13
61
HDL: Low
4
40
Radiation Induced Illness
12
38
Arteriosclerosis
6
34
Breast Cancer
19
33
Diabetes Mellitus: Type 2: Prevention
4
33
Coronary Artery Disease
5
32
Diabetes Mellitus: Type 2
9
31
Thrombosis
4
31
All-Cause Mortality
2
30
Cardiovascular Disease: Prevention
3
30
Hemorrhoids
3
30
Obesity
7
29
Depression
7
28
Lipopolysaccharide-Induced Toxicity
14
28
DNA damage
12
26
Cognitive Decline/Dysfunction
4
24
Clotting
4
23
Aging
8
22
C-Reactive Protein
3
22
Cancers: All
21
22
Cholesterol: LDL/HDL ratio
3
22
Colon Cancer
18
22
Glaucoma
2
22
Alzheimer's Disease
15
21
Esophageal Cancer
3
21
Allergic Rhinitis
2
20
Cancer Mortality
1
20
Cardiac Mortality
1
20
Chronic Disease
2
20
Deep Vein Thrombosis
2
20
Diabetes: Cardiovascular Illness
2
20
Ocular Hypertension
1
20
Parkinson's Disease
9
20
Prehypertension
1
20
Rectal Cancer
1
20
Smoking
2
20
Liver Cancer
8
18
Colorectal Cancer: Prevention
3
17
Aging: Brain
4
16
Prostate Cancer
13
16
Insulin Resistance
4
15
Lipid Peroxidation
10
15
Metabolic Syndrome X
3
14
Ovarian Cancer
4
14
Chemically-Induced Liver Damage
7
13
Heart Failure
3
13
Lung Cancer
11
13
Myocardial Infarction
3
13
Pesticide Toxicity
3
13
Rheumatoid Arthritis
3
13
Sunburn
3
13
Aging Skin
3
12
Arsenic Poisoning
2
12
Helicobacter Pylori Infection
3
12
Hyperuricemia
2
12
Menopausal Syndrome
2
12
Gout
2
11
High Cholesterol
2
11
Neurodegenerative Diseases
8
11
Skin Diseases: Photo-Aging
2
11
Stroke
2
11
Aflatoxicosis
1
10
Aphthous Ulcer
1
10
Asthma
1
10
Athletic Performance
1
10
Athletic Performance: Recovery
1
10
Bile Duct Cancer
1
10
Bladder Degeneration
1
10
Blood Platelet Disorders
1
10
Bone Fractures
1
10
Brain Edema
1
10
Chemotherapy
1
10
Chronic Obstructive Pulmonary Disease
1
10
Climacteric
1
10
Common Cold
1
10
Dental Caries
1
10
Depression
1
10
Dystrophic retinal detachment (DRD)
1
10
Edema
1
10
Erectile Dysfunction
1
10
Eye Diseases: Vitreous Disorders
1
10
Gallbladder Cancer
1
10
Head and Neck Cancer
1
10
Heart Disease: Ischemic
1
10
Hematuria
1
10
Jet Lag
1
10
Leg Edema
1
10
Libido: Low
1
10
Macular Degeneration
1
10
Osteoarthritis: Knee
1
10
Peripheral vitreochoreoretinal dystrophies (PVCRD)
1
10
Post-Thrombotic Syndrome
1
10
Postmenopausal Disorders: Insomnia
1
10
Postoperative Recovery
1
10
Premenstrual syndrome
1
10
Pulmonary Diseases
1
10
Retinal Detachment
1
10
Sexaul Dysfunction
1
10
Thromboembolism
1
10
Tinnitus
1
10
Venous Thrombosis
1
10
Vericose Veins: Bladder
1
10
Wrinkles
1
10
Hyperlipidemia
5
9
Pancreatic Cancer
5
9
Brain Inflammation
6
8
Cancers: Drug Resistant
7
8
Hyperglycemia
7
8
Cancer Metastasis
4
7
Gastric Ulcer
4
7
Hypercholesterolemia
4
7
Liver Cancer: Prevention
2
7
Breast Cancer: Metastatic
3
6
Cervical Cancer
6
6
Diabetes Mellitus: Type 1
4
6
Myocardial Ischemia
3
6
Breast Cancer: Triple Negative
3
5
Cancers: Multi-Drug Resistant
5
5
Carcinoma: Non-Small-Cell Lung
5
5
Chemotherapy-Induced Toxicity: Cisplatin
3
5
Diabetic Complications
3
5
Melanoma
4
5
Memory Disorders
3
5
Oral Cancer
3
5
Tumors
4
5
Advanced Glycation End products (AGE)
3
4
Aging: Immunosenecence
2
4
Alcohol Toxicity
2
4
Alcoholic Liver Disease
2
4
Anxiety
2
4
Atherosclerosis
3
4
Cerebral Ischemia
2
4
HIV Infections
4
4
High Fat Diet
2
4
Immune Disorders: Low Immune Function
2
4
Inflammatory Bowel Diseases
2
4
Neuroblastoma
2
4
Seizures
2
4
Ultraviolet Radiation Induced Damage
4
4
Allergies
2
3
Brain Injury: Traumatic
2
3
Brain Ischemia
3
3
Cholera
2
3
Dementia
3
3
Diabetes: Cataract
2
3
Dioxin Toxicity
2
3
Dyslipidemias
2
3
Hydrogen Peroxide Induced Toxicity
3
3
Hypoxia
2
3
Liver Damage
2
3
MRSA
2
3
Nonalcoholic fatty liver disease (NAFLD)
2
3
Osteoporosis
2
3
Snake Bite: Venom Toxicity
2
3
Abdominal Obesity (Midsection Fat)
1
2
Aluminum Toxicity
1
2
Anaphylaxis
1
2
Arthritis
1
2
Aspirin-Induced Toxicity
1
2
Autism
1
2
Bladder Cancer
2
2
Bone Diseases
1
2
Brain Injury: Hippocampal Damage
1
2
Brain: Microglial Activation
2
2
Breast Cancer: Lung Metastasis
1
2
Candida Albicans
2
2
Cardiomyopathy
1
2
Cataract
1
2
Cerebral Vasospasm
1
2
Chemotherapy-Induced Toxicity: Gentamicin
1
2
Chikungunya Virus
2
2
Colon Polyps
1
2
Convulsions
1
2
Cystic Fibrosis
2
2
Diabetes: Cognitive Dysfunction
1
2
Diabetic Nephropathy
1
2
Diesel Exhaust Particle Toxicity
1
2
Dopamine Deficiency
1
2
Estrogen Dominance
2
2
Fatty Liver
1
2
Food Allergies
1
2
Fructose-Induced Toxicity
1
2
Giardiasis
2
2
Heat Stroke
1
2
High Fructose Diet
1
2
Hypothyroidism
1
2
IgA Deficiency
1
2
IgE-Mediated Hypersensitivity
1
2
Infertility: Aging Associated
1
2
Infertility: Female
1
2
Infertility: Male
1
2
Intestinal Diseases
1
2
Intestinal Permeability
2
2
Iron Overload
1
2
Irritable Bowel Syndrome
1
2
Ischemia
1
2
Kidney Damage: Chemically-Induced
1
2
Leaky Gut Syndrome
2
2
Learning disorders
1
2
Leukemia
2
2
Leukemia: Acute myelogenous leukemia (AML)
1
2
Leukemia: Chronic myelogenous leukemia (CML)
1
2
Liver Injury: Ischemia/reperfusion
1
2
Low Immune Function: Thymus Dysfunction
1
2
Lymphoma
1
2
Mercury Poisoning
1
2
Mouse Endogenous Retroviruses
1
2
NSAID-induced toxicity
1
2
Osteoarthritis
1
2
Ovariectomy Associated Adverse Changes
1
2
Periodontitis
1
2
Pesticide-Induced Toxicity: Organophosphates
1
2
Petroleum Exposure And Toxicity
1
2
Prenatal Chemical Exposures
1
2
Prenatal Nutrition: Health of the Offspring
1
2
Promyelocytic leukemia
2
2
Prostatic Hyperplasia: Benign
1
2
Radiation Induced Illness: Bone Marrow
1
2
Scars
1
2
Skin Cancer
1
2
Skin Cancer: Prevention
1
2
Sperm Quality: Low
1
2
Squamous cell carcinoma
1
2
Staphylococcus aureus infection
2
2
Systemic Lupus Erythematosus
1
2
Thyroid Cancer
2
2
Wound Healing
1
2
Acute lymphoblastic leukemia (ALL)
1
1
Allergic Airway Diseases
1
1
Amyloidosis
1
1
Amyotrophic Lateral Sclerosis
1
1
Anemia: Hemolytic
1
1
Aspergillosis
1
1
Bacillus subtilis infections
1
1
Bacterial Infections
1
1
Benzo[a]pyrene-induced Toxicity
1
1
Brain: Oxidative Stress
1
1
Cancers
1
1
Candida Infection
1
1
Chemotherapy and Radiation Toxicity
1
1
Cholangiocarcinoma
1
1
Chronic Myeloid Leukemia
1
1
Clostridium Infections
1
1
Colitis
1
1
Copper Toxicity
1
1
Cryptosporidiosis
1
1
Cytomegalovirus Infections
1
1
Epstein-Barr Virus Infections
1
1
Escherichia coli Infections
1
1
Excitotoxicity
1
1
Fatigue
1
1
Gastric Cancer
1
1
Glioblastoma
1
1
Glioma
1
1
Glucosephosphate Dehydrogenase Deficiency
1
1
HSV-1
1
1
HSV-2
1
1
High Homocysteine
1
1
Hyperinsulinism
1
1
Hypertension: Pulmonary
1
1
Influenza in Swine
1
1
Kidney Damage: Drug-Induced
1
1
Klebsiella Infections
1
1
Leishmaniasis
1
1
Liver Disease
1
1
Malaria
1
1
Malignant Melanoma
1
1
Micrococcus luteus infections
1
1
Mycobacterium tuberculosis
1
1
Neurological Conditions
1
1
Non-Small-Cell Lung Carcinoma
1
1
Osteosarcoma
1
1
Protozoan Infections
1
1
Pseudomonas aeruginosa
1
1
Psychiatric Disorders
1
1
Radiation
1
1
Radiation-Induced Illness: Cesium-137 Exposure
1
1
Rhinovirus Infection
1
1
Schizophrenia
1
1
Simian virus 40 (SV40)
1
1
Staphylococcus epidermidis
1
1
Sugar (Sucrose) Toxicity
1
1
Swine Flu Associated Virus
1
1
Tertiary butyl hydroperoxide toxicity
1
1
Testicular Cancer
1
1
Triglycerides: Elevated
1
1
Vibrio Infections
1
1
Weight Problems
1
1
129 Pharmacological Actions Researched for Flavonoids
Name
AC
CK
Focus
Antioxidants
147
310
Chemopreventive
37
116
Anti-Inflammatory Agents
51
94
Antiproliferative
64
81
Apoptotic
66
79
Neuroprotective Agents
36
68
Platelet Aggregation Inhibitors
7
62
NF-kappaB Inhibitor
22
46
Tumor Necrosis Factor (TNF) Alpha Inhibitor
22
46
Anticarcinogenic Agents
22
40
Hypotensive
2
40
Cell cycle arrest
27
39
Hypoglycemic Agents
15
39
Cyclooxygenase 2 Inhibitors
21
38
Cardioprotective
11
36
Interleukin-1 beta downregulation
15
34
Antineoplastic Agents
21
33
Anti-Apoptotic
15
32
Radioprotective
12
29
Antidepressive Agents
6
27
Hepatoprotective
14
26
Interleukin-6 Downregulation
15
26
Analgesics
4
24
Antihypertensive Agents
5
24
Vasodilator Agents
4
23
Enzyme Inhibitors
17
21
Anti-metastatic
11
19
Anticholesteremic Agents
4
15
Chemotherapeutic
12
13
MicroRNA modulator
3
13
Anti-Allergic Agents
2
12
Anti-Platelet
2
11
Nitric Oxide Enhancer
2
11
Anti Inflammatory
2
10
Anti-Bacterial Agents
9
10
Anti-thrombotic
1
10
Calcium Channel Blockers
1
10
Cardiovascular Agents
1
10
Detoxifier
1
10
Hypolipidemic
7
10
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
1
10
Matrix metalloproteinase-3 (MMP-3) inhibitor
1
10
Chemosensitizer
8
9
Immunomodulatory
5
9
Tumor Suppressor Protein p53 Upregulation
8
9
Anti-Ulcer Agents
4
8
Antiviral Agents
7
7
Matrix metalloproteinase-2 (MMP-2) inhibitor
4
7
Alpha-glucosidase inhibitor
4
5
Anti-Angiogenic
4
5
Antifungal Agents
5
5
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
1
5
Interleukin-10 downregulation
3
5
Nitric Oxide Inhibitor
3
5
Nrf2 activation
3
5
Photoprotective
4
5
Renoprotective
3
5
Anti-Anxiety Agents
2
4
Anticonvulsants
2
4
Antimutagenic Agents
4
4
Brain-derived neurotrophic factor modulator
2
4
Chemoprotective Agents
2
4
Genoprotective
3
4
Malondialdehyde Down-regulation
2
4
Phase II Detoxification Enzyme Inducer
2
4
Anti-HIV Agents
3
3
Antimicrobial
2
3
Cyclooxygenase 1 Inhibitor
2
3
Cytoprotective
2
3
5-Lipoxygenase Inhibitor
2
2
Aldose reductase inhibitor
1
2
Alpha-amylase inhibitor
2
2
Anti-Tumor
1
2
Antidiarrheals
1
2
Antinoceceptive
1
2
Caspase-3 Activation
2
2
Cyclooxygenase Inhibitors
1
2
Cytotoxic
2
2
Dopaminergic
1
2
Gastroprotective
2
2
Heme oxygenase-1 up-regulation
1
2
Interferon Gamma Reducer
1
2
Interleukin-4 downregulation
2
2
Iron Chelating Agents
1
2
Matrix metalloproteinase-9 (MMP-9) inhibitor
1
2
Proteasome Inhibitors
2
2
Superoxide Dismutase Up-regulation
1
2
Vascular Cell Adhesion Molecule-1 Inhibitor
2
2
Vascular Endothelial Growth Factor A Inhibitor
1
2
Acetylcholinesterase Inhibitor
1
1
Anti-Estrogenic
1
1
Antiprotozoal Agents
1
1
Aromatase Inhibitors
1
1
Cytotoxicity
1
1
DNA Repair Up-regulation
1
1
E-cadherin down-regulation
1
1
Estrogen Receptor Agonist
1
1
Expectorants
1
1
Forkhead Transcription Factor Family O (FOXO) Modulator
1
1
Gastrointestinal Agents
1
1
Glucagon Like Peptide 1 (GLP-1) Down-Regulation
1
1
Glucagon Like peptide 1 (GLP-1) Up-regulation
1
1
Gluconeogenesis Inhibitor
1
1
Glutathione Upregulation
1
1
Histamine Antagonists
1
1
Histone deacetylase inhibitor
1
1
Hypoxia-inducible factor-1 (HIF-1) inhibitor
1
1
Immunostimulatory
1
1
Insulin-releasing
1
1
Interleukin-5 downregulation
1
1
Leishmanicidal
1
1
Leukotriene Antagonists
1
1
Matrix metalloproteinase-1 (MMP-1) inhibitor
1
1
Metal Chelation: Copper
1
1
Neurominidase Inhibitor
1
1
Osteoprotective
1
1
P-glycoprotein Inhibitors
1
1
P21 Activation
1
1
P38 Mitogen-Activated Protein Kinase Modulator
1
1
Postaglandin PGE2 downregulation
1
1
Prostaglandin PGE2 downregulation
1
1
Radiosensitizer
1
1
Sedative effects
1
1
Telomere Protective
1
1
Topoisomerase II Inhibitor
1
1
Vasoprotective
1
1
Wnt/β-catenin signaling pathway modulation
1
1
Xanthine oxidase inhibitor
1
1
interleukin-13 down-regulation
1
1
Research Articles
523
Cumulative Knowledge Score
846
Overall Research Rating
EXCELLENT
View the Evidence:
867 Abstracts with Flavonoids Research
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[+]
"Dietary flavonoid for preventing colorectal neoplasms."
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Cochrane Database Syst Rev. 2012 ;8:CD009350. Epub 2012 Aug 15. PMID:
22895989
Article Published Date
: Dec 31, 2011
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
[+]
Cocoa products have blood-pressure lowering capacity.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Hypertens. 2010 Jan;23(1):97-103. Epub 2009 Nov 12. PMID:
19910929
Article Published Date
: Jan 01, 2010
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Hypertension
Pharmacological Actions
:
Hypotensive
[+]
Dark chocolate is superior to placebo in reducing systolic hypertension or diastolic prehypertension.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: BMC Med. 2010;8:39. Epub 2010 Jun 28. PMID:
20584271
Article Published Date
: Jan 01, 2010
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Hypertension
,
Prehypertension
Pharmacological Actions
:
Hypotensive
[+]
Flavonoid intake reduces all-cause mortality.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2015 Apr 1. Epub 2015 Apr 1. PMID:
25832340
Article Published Date
: Mar 31, 2015
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
All-Cause Mortality
,
Cancer Mortality
,
Cardiac Mortality
[+]
Flavonoids have a promising role in improving visual function in patients with glaucoma and ocular hypertension.
Sep 03, 2015
Click here to read the entire abstract
Pubmed Data
: Graefes Arch Clin Exp Ophthalmol. 2015 Sep 4. Epub 2015 Sep 4. PMID:
26340868
Article Published Date
: Sep 03, 2015
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Cocoa
,
Flavonoids
,
Green Tea
,
Red Wine Extract
Diseases
:
Glaucoma
,
Ocular Hypertension
[+]
High intake of flavonols may reduce the risk of colon cancer and high intake of flavones may reduce the risk of rectal cancer.
Jul 22, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Jul 23 ;10(7). Epub 2018 Jul 23. PMID:
30041489
Article Published Date
: Jul 22, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Quercetin
Diseases
:
Colorectal Cancer
,
Rectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Higher intakes of total flavonoids and subclasses are associated with lower risk of T2DM.
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Medicine (Baltimore). 2018 May ;97(19):e0686. PMID:
29742713
Article Published Date
: Apr 30, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavan-3-ols
,
Flavonoids
,
Isoflavones
Diseases
:
Diabetes Mellitus: Type 2: Prevention
Additional Keywords
:
Risk Reduction
[+]
The present study suggests the intake of flavonols and flavones is associated with a decreased risk of breast cancer.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(1):e54318. Epub 2013 Jan 18. PMID:
23349849
Article Published Date
: Dec 31, 2012
Study Type
: Meta Analysis
Additional Links
Substances
:
Flavonoids
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
The present systematic review suggests that the dietary intakes of six classes of flavonoids significantly decrease the risk of cardiovascular diseases.
Jan 13, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2014 Jan 14 ;111(1):1-11. Epub 2013 Aug 16. PMID:
23953879
Article Published Date
: Jan 13, 2014
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
,
Proanthocyanidins
[+]
High polyphenol chocolate is effective in improving the atherosclerotic cholesterol profile in patients with diabetes by increasing HDL cholesterol and improving the cholesterol:HDL ratio.
Nov 01, 2010
Click here to read the entire abstract
Pubmed Data
: Diabet Med. 2010 Nov;27(11):1318-21. PMID:
20968113
Article Published Date
: Nov 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: LDL/HDL ratio
,
Diabetes: Cardiovascular Illness
,
HDL: Low
[+]
Plasma polyphenols and antioxidants, oxidative DNA damage and endothelial function in a diet and wine intervention study in humans.
Dec 31, 1998
Click here to read the entire abstract
Pubmed Data
: Drugs Exp Clin Res. 1999 ;25(2-3):133-41. PMID:
10370876
Article Published Date
: Dec 31, 1998
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Red Wine
Diseases
:
Arteriosclerosis
,
DNA damage
,
Endothelial Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
"Kidney function in metabolic syndrome may be improved with Pycnogenol®."
May 31, 2010
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2010 Jun ;52(2 Suppl 1):27-32. PMID:
20657531
Article Published Date
: May 31, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Metabolic Syndrome X
Pharmacological Actions
:
Antihypertensive Agents
[+]
A Chinese green tea polyphenol extract has evident anti-plaque effect.
Sep 01, 2000
Click here to read the entire abstract
Pubmed Data
: Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Sep;35(5):383-4. PMID:
11780252
Article Published Date
: Sep 01, 2000
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
Diseases
:
Dental Caries
[+]
A combination of apigenin and EGCG prevent colorectal cancer recurrence.
Apr 14, 2008
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2008 Apr 14;14(14):2187-93. PMID:
18407592
Article Published Date
: Apr 14, 2008
Study Type
: Human Study
Additional Links
Substances
:
Apigenin
,
Catechin
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
A combination of diosmin and hesperidin significantly reduces bleeding in patients with acute internal hemorrhoids.
Jun 01, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Ther. 2005 Jun;27(6):746-54. PMID:
16117981
Article Published Date
: Jun 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Hesperidin
Diseases
:
Hemorrhoids
[+]
A combination of pine bark extract and nattokinase prevents venous thrombosis in long-haul flights.
Sep 01, 2003
Click here to read the entire abstract
Pubmed Data
: Angiology. 2003 Sep-Oct;54(5):531-9. PMID:
14565628
Article Published Date
: Sep 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Nattokinase
Diseases
:
Deep Vein Thrombosis
,
Thromboembolism
,
Thrombosis
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
A flavonoid supplement improves leg health and reduces fluid retention in premenopausal women.
Jan 01, 2004
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2004 Jan;11(1):11-7. PMID:
14971717
Article Published Date
: Jan 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Premenstrual syndrome
Additional Keywords
:
Oligomeric Procyanidins
,
Water Retention
[+]
A flavonol-rich diet may decrease the risk of advanced adenoma recurrence.
May 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Epidemiol Biomarkers Prev. 2008 Jun ;17(6):1344-53. PMID:
18559549
Article Published Date
: May 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
A polyphenol-rich beverage reduces symptoms associated with the common cold.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Oct;104(8):1156-64. Epub 2010 May 21. PMID:
20487584
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Common Cold
[+]
Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysunfction in smokers.
Oct 04, 2005
Click here to read the entire abstract
Pubmed Data
: J Am Coll Cardiol. 2005 Oct 4;46(7):1276-83. PMID:
16198843
Article Published Date
: Oct 04, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Endothelial Dysfunction
,
Smoking
[+]
Apple peel extract inhibits the growth of Helicobacter pylori, and attenuates damage to the gastric mucosa caused by neutrophils.
Sep 09, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 9;57(17):7743-9. PMID:
19691323
Article Published Date
: Sep 09, 2009
Study Type
: Human Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Helicobacter Pylori Infection
Additional Keywords
:
Plant Extracts
,
Proanthocyanidins
[+]
Association of total flavonoid intake with hypo-HDL-cholesterolemia among Korean adults: effect modification by polyunsaturated fatty acid intake.
Jan 09, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 Jan 10 ;12(1). Epub 2020 Jan 10. PMID:
31936778
Article Published Date
: Jan 09, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyunsaturated Fatty Acids (PUFAs)
,
Proanthocyanidins
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Auricular acupressure at some specific acupoints can significantly improve the absorption of naringenin and hesperetin in the extracts form C. aurantium L.
Apr 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Altern Complement Med. 2008 May ;14(4):423-5. PMID:
18576924
Article Published Date
: Apr 30, 2008
Study Type
: Human Study
Additional Links
Substances
:
Bitter Orange
,
Flavonoids
,
Naringenin
Therapeutic Actions
:
Acupressure: Auricular
Additional Keywords
:
Absorption
[+]
Bilberry has anti-inflammatory properties.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Sep;49(6):345-55. Epub 2010 Feb 2. PMID:
20119859
Article Published Date
: Sep 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Sep;138(9):1671-6. PMID:
18716168
Article Published Date
: Sep 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Insulin Resistance
[+]
Blueberry flavonoid consumption promotes a positive mood and are a possible way to prevent dysphoria and depression.
Feb 19, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Feb 20 ;9(2). Epub 2017 Feb 20. PMID:
28230732
Article Published Date
: Feb 19, 2017
Study Type
: Human Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Cocoa inhibits LDL oxidation both in vitro and ex vivo.
Apr 06, 1999
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 1999 Apr 6;440(2):181-8. PMID:
11185658
Article Published Date
: Apr 06, 1999
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Arteriosclerosis
,
Cholesterol: Oxidation
Pharmacological Actions
:
Antioxidants
[+]
Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility and increasing serum total antioxidant capacity and HDL-cholesterol concentrations.
Nov 01, 2001
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2001 Nov;74(5):596-602. PMID:
11684527
Article Published Date
: Nov 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Cardiovascular Diseases
,
Cholesterol: Oxidation
,
HDL: Low
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Proanthocyanidins
[+]
Coffee appears to have a beneficial effect on pulmonary function, among non-smokers.
Oct 15, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2010 Oct 15;127(8):1758-68. PMID:
19372215
Article Published Date
: Oct 15, 2010
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Flavonoids
,
Polyphenols
Diseases
:
Pulmonary Diseases
,
Smoking
[+]
Comparison of centella with flavonoids for treatment of symptoms in hemorrhoidal disease and after surgical intervention.
May 13, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2020 May 14 ;10(1):8009. Epub 2020 May 14. PMID:
32409760
Article Published Date
: May 13, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Gotu Kola
Diseases
:
Hemorrhoids
[+]
Consumption of flavanone-rich citrus juice in quantities commonly consumed can acutely enhance blood flow to the brain in healthy young adults.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2016 Dec ;116(12):2160-2168. Epub 2017 Jan 16. PMID:
28091350
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Vitamin C
[+]
Consumption of high flavanol dark chocolate confers modest improvements in cardiovascular function.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Vascul Pharmacol. 2015 Aug ;71:70-8. Epub 2015 Apr 11. PMID:
25869509
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Cocoa
,
Flavonoids
Diseases
:
Cardiovascular Disease: Prevention
,
Cardiovascular Diseases
Pharmacological Actions
:
Cardiovascular Agents
[+]
Consumption of phytochemical-rich foods may prevent the development of hypertension.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Clin Nutr. 2015 Mar ;69(3):392-8. Epub 2014 Nov 12. PMID:
25387902
Article Published Date
: Feb 28, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Hypertension
Additional Keywords
:
Dietary Modification
,
Plant Extracts
,
Risk Reduction
[+]
Consumptions of citrus fruits, strawberries and grapes were found associated with a lower stroke risk in women.
Jan 28, 2021
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2021 Jan 29:1-8. Epub 2021 Jan 29. PMID:
33509322
Article Published Date
: Jan 28, 2021
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Grape
,
Strawberry
Diseases
:
Stroke
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans.
Jun 02, 2009
Click here to read the entire abstract
Pubmed Data
: Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9033-8. Epub 2009 May 18. PMID:
17344491
Article Published Date
: Jun 02, 2009
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: Oxidation
,
HDL: Low
Pharmacological Actions
:
Antioxidants
[+]
Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol.2008 Dec;46(12):3586-92. Epub 2008 Sep 3 PMID:
15454274
Article Published Date
: Dec 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Flavonoids
,
Polyphenols
Diseases
:
Cholesterol: LDL/HDL ratio
,
Cholesterol: Oxidation
,
HDL: Low
[+]
Dark chocolate improves coronary vasomotion and reduces platelet reactivity.
Nov 20, 2007
Click here to read the entire abstract
Pubmed Data
: Circulation. 2007 Nov 20;116(21):2376-82. Epub 2007 Nov 5. PMID:
17984375
Article Published Date
: Nov 20, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Blood Platelet Disorders
,
Clotting
,
Coronary Artery Disease
,
Endothelial Dysfunction
Pharmacological Actions
:
Anti-Platelet
,
Vasodilator Agents
[+]
Dietary flavonoid intake at midlife and healthy aging in women.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2014 Dec ;100(6):1489-97. Epub 2014 Oct 29. PMID:
25411284
Article Published Date
: Nov 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Apple
,
Berries: All
,
Flavonoids
,
Onion
,
Orange
Diseases
:
Aging
,
Cancers: All
,
Cardiovascular Diseases
,
Diabetes Mellitus: Type 2
,
Hypertension
,
Stroke
Additional Keywords
:
Risk Reduction
[+]
Dietary flavonoids improve urinary arsenic elimination among Mexican women.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2018 Jul ;55:65-71. Epub 2018 Apr 21. PMID:
29914629
Article Published Date
: Jun 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Apigenin
,
Flavan-3-ols
,
Flavonoids
Diseases
:
Arsenic Poisoning
Pharmacological Actions
:
Detoxifier
Problem Substances
:
Arsenic
[+]
Flavanone intake is inversely associated with esophageal cancer risk and may account, with vitamin C, for the protective effect of fruit, especially citrus fruit, on esophageal cancer.
Apr 10, 2000
Click here to read the entire abstract
Pubmed Data
: Arch Intern Med. 2000 Apr 10;160(7):1009-13. PMID:
17192901
Article Published Date
: Apr 10, 2000
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Grapefruit
,
Lemon Juice
,
Orange
,
Vitamin C
Diseases
:
Esophageal Cancer
Additional Keywords
:
Risk Reduction
[+]
Flavonoid antioxidants may have therapeutic value in PVCRD and DRD for the purpose of improving and stabilizing the visual functions and for neuroprotection.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Inflamm Res. 2009 Aug;58(8):513-21. Epub 2009 Mar 11. PMID:
15384840
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
Diseases
:
Dystrophic retinal detachment (DRD)
,
Eye Diseases: Vitreous Disorders
,
Peripheral vitreochoreoretinal dystrophies (PVCRD)
,
Retinal Detachment
Pharmacological Actions
:
Antioxidants
[+]
Flavonoid consumption may be beneficial for disease prevention.
May 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Diabetes. 2017 May 15 ;7(5):e276. Epub 2017 May 15. PMID:
28504712
Article Published Date
: May 14, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
C-Reactive Protein
,
Chronic Disease
,
Inflammation
,
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Flavonoid consumption reduces the risk of esophageal cancer.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2007 Jun;21(6):501-6. PMID:
19444905
Article Published Date
: Jun 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Esophageal Cancer
Additional Keywords
:
Proanthocyanidins
,
Risk Reduction
[+]
Flavonoid intake and the risk of age-related cataract in China's Heilongjiang Province.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2015 ;59:29564. Epub 2015 Dec 11. PMID:
26652740
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Quercetin
Diseases
:
Cataract
Additional Keywords
:
Risk Reduction
[+]
Flavonoid-rich dark chocolate improves endothelial function and increases plasma antioxidant concentrations in healthy adults.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Am Coll Nutr. 2004 Jun;23(3):197-204. PMID:
15190043
Article Published Date
: Jun 01, 2004
Study Type
: Human Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
Diseases
:
Endothelial Dysfunction
[+]
Flavonoid-rich dark chocolate intake significantly improved coronary circulation in healthy adults.
Jan 24, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Cardiol. 2009 Jan 24;131(3):424-9. Epub 2007 Nov 28. PMID:
18045712
Article Published Date
: Jan 24, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Coronary Artery Disease
[+]
Flavonoids (hesperidin) have therapeutic value in the treatment of bleeding bladder varices.
Oct 01, 2003
Click here to read the entire abstract
Pubmed Data
: Actas Urol Esp. 2003 Oct;27(9):732-4. PMID:
14626685
Article Published Date
: Oct 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Bladder Degeneration
,
Hematuria
,
Vericose Veins: Bladder
[+]
Flavonoids and omega 3-based compoundhad beneficial effects for muscular dystrophies treatment.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Neurol. 2019 ;10:755. Epub 2019 Jul 23. PMID:
31396142
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Omega-3 Fatty Acids
Diseases
:
Muscular Dystrophies
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Flavonoids contained in fruits and vegetables, especially flavanones, might reduce the risk of non-allergic rhinitis.
Jan 29, 2020
Click here to read the entire abstract
Pubmed Data
: Public Health Nutr. 2020 Jan 30:1-9. Epub 2020 Jan 30. PMID:
31996276
Article Published Date
: Jan 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
Prophylactic Agents
Additional Keywords
:
Risk Reduction
[+]
Flavonoids from vegetables and fruits may be linked with the reduced risk of colorectal cancer.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2016 Oct ;116(7):1275-1287. Epub 2016 Sep 21. PMID:
27650133
Article Published Date
: Sep 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Fruit: All
,
Vegetables: All
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Additional Keywords
:
COLORECTAL CANCER
,
Colorectal Cancer: Prevention
,
Flavonoids
,
Fruit: All
,
Risk Reduction
,
Vegetables: All
[+]
Flavonol intake and cognitive decline in middle-aged adults.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2015 Dec ;18(12):1327-32. Epub 2015 Sep 1. PMID:
26325006
Article Published Date
: Nov 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Kaempferol
,
Myricetin
,
Quercetin
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Flavonols and catechins have proved to be the most promising molecules for a potential protective role against prostate cancer.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2018 Aug ;39:14-18. Epub 2018 May 15. PMID:
30012385
Article Published Date
: Jul 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
Hesperidin has therapeutic value in the treatment of recurrent aphthous stomatitis.
Apr 01, 2006
Click here to read the entire abstract
Pubmed Data
: Georgian Med News. 2006 Apr(133):31-3. PMID:
16705221
Article Published Date
: Apr 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
Aphthous Ulcer
[+]
High intake of flavonoids is associated with decreased carotid atherosclerosis in middle-aged Finnish men.
Sep 30, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2007 Oct ;98(4):814-8. Epub 2007 Apr 30. PMID:
17466095
Article Published Date
: Sep 30, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Cardioprotective
[+]
Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women.
Sep 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2012 Oct ;96(4):781-8. Epub 2012 Aug 22. PMID:
22914551
Article Published Date
: Sep 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Vasoprotective
[+]
Higher consumption of red wine, tea, peppers, blueberries and strawberries, was associated with reduced risk of total and cause-specific mortality.
Jun 12, 2017
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2017 Jun 13:1-8. Epub 2017 Jun 13. PMID:
28606222
Article Published Date
: Jun 12, 2017
Study Type
: Human Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
,
Red Wine Extract
,
Strawberry
Diseases
:
All-Cause Mortality
Additional Keywords
:
Risk Reduction
[+]
Higher dietary intake of flavonoid may be inversely associated with depressive symptoms.
Apr 23, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2018 Apr 24 ;23(5). Epub 2018 Apr 24. PMID:
29695122
Article Published Date
: Apr 23, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Depression
Additional Keywords
:
depression
,
Flavonoids
,
Risk Reduction
[+]
Higher dietary intakes of flavonols may be associated with reduced risk of developing Alzheimer dementia.
Jan 28, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurology. 2020 Jan 29. Epub 2020 Jan 29. PMID:
31996451
Article Published Date
: Jan 28, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Higher flavonoid intake is associated with lower IL-1β.
Jan 29, 2020
Click here to read the entire abstract
Pubmed Data
: J Clin Periodontol. 2020 Jan 30. Epub 2020 Jan 30. PMID:
31999847
Article Published Date
: Jan 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Periodontal Diseases
,
Periodontal Wound Healing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Higher flavonoid intakes may be associated with lower depression risk.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2016 09 ;104(3):704-14. Epub 2016 Jul 13. PMID:
27413131
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Risk Reduction
[+]
Higher intake of black tea and particular classes of flavonoids were associated with lower risk of fracture related hospitalizations in elderly women at high risk of fracture.
Aug 11, 2015
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2015 Aug 12. Epub 2015 Aug 12. PMID:
26269364
Article Published Date
: Aug 11, 2015
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
Diseases
:
Bone Fractures
Additional Keywords
:
Risk Reduction
[+]
Higher intake of flavonoids, particularly from berries, appears to reduce rates of cognitive decline in older adults.
Jun 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Neurol. 2012 Jul ;72(1):135-43. Epub 2012 Apr 26. PMID:
22535616
Article Published Date
: Jun 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Berries: All
,
Blueberry
,
Flavonoids
,
Strawberry
Diseases
:
Aging
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of anthocyanins and flavonols and their anti-inflammatory effects may be a key component underlying the reduction in risk of certain chronic diseases.
May 26, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2015 May 27. Epub 2015 May 27. PMID:
26016863
Article Published Date
: May 26, 2015
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Fruit: All
,
Vegetables: All
Diseases
:
Chronic Disease
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of flavonols and flavanones as well as black tea consumption may be associated with lower risk of ovarian cancer.
Oct 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2014 Nov ;100(5):1344-51. Epub 2014 Aug 20. PMID:
25332332
Article Published Date
: Oct 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Black Tea
,
Flavonoids
Diseases
:
Ovarian Cancer
Additional Keywords
:
Risk Reduction
[+]
Higher intakes of fruit-based flavonoids were associated with a lower risk of nonfatal MI and ischemic stroke in men.
Aug 02, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Clin Nutr. 2016 Aug 3. Epub 2016 Aug 3. PMID:
27488237
Article Published Date
: Aug 02, 2016
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Fruit: All
Diseases
:
Cardiovascular Diseases
,
Myocardial Infarction
,
Stroke
Additional Keywords
:
Risk Reduction
[+]
Individuals using the Army Physical Fitness Test while supplementing with Pycnogenol had a lower increase in oxidative stress with a faster recovery to almost normal levels.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: J Sports Med Phys Fitness. 2013 Dec ;53(6):644-54. PMID:
24247188
Article Published Date
: Nov 30, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Athletic Performance
,
Athletic Performance: Recovery
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Supplementation
[+]
Intake of flavonoid-rich wine, tea, and chocolate by elderly men and women is associated with better cognitive test performance.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2009 Jan;139(1):120-7. Epub 2008 Dec 3. PMID:
19056649
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
,
Green Tea
,
Wine
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
[+]
Intake of total polyphenols and some classes of polyphenols is inversely associated with diabetes in elderly People at high cardiovascular disease risk.
Mar 08, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2016 Mar 9. Epub 2016 Mar 9. PMID:
26962181
Article Published Date
: Mar 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Disease: Prevention
,
Diabetes Mellitus: Type 2: Prevention
Additional Keywords
:
Risk Reduction
[+]
L-arginine in combination with Pycnogenol causes a significant improvement in sexual function in men with erectile dysfunction without any side effects.
May 01, 2003
Click here to read the entire abstract
Pubmed Data
: J Sex Marital Ther. 2003 May-Jun;29(3):207-13. PMID:
12851125
Article Published Date
: May 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Arginine
,
Flavonoids
Diseases
:
Erectile Dysfunction
Pharmacological Actions
:
Nitric Oxide Enhancer
,
Platelet Aggregation Inhibitors
[+]
Moderate consumption of chocolate might be associated with a lower risk of heart failure in male physicians.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Heart Fail. 2014 Dec ;16(12):1372-6. Epub 2014 Oct 14. PMID:
25311633
Article Published Date
: Nov 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Heart Failure
Pharmacological Actions
:
Cardioprotective
[+]
Modulation of aflatoxin biomarkers in human blood and urine by green tea polyphenols intervention.
Jan 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Carcinogenesis. 2008 Feb ;29(2):411-7. Epub 2008 Jan 12. PMID:
18192689
Article Published Date
: Jan 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Tea
Diseases
:
Aflatoxicosis
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
Problem Substances
:
Aflatoxin
[+]
One week of dark chocolate ingestion improved lipid profiles and decreased platelet reactivity within the total group while reducing inflammation only in women.
Jul 01, 1999
Click here to read the entire abstract
Pubmed Data
: Neurotoxicol Teratol. 1999 Jul-Aug;21(4):349-57. PMID:
19005437
Article Published Date
: Jul 01, 1999
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
C-Reactive Protein
,
Clotting
,
Thrombosis
[+]
People who preferentially consume high amounts of quercetin-containing foods have a reduced risk of thrombosis and potential CVD risk.
Aug 31, 2006
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2006 Sep ;96(3):482-8. PMID:
16925853
Article Published Date
: Aug 31, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Onion
,
Quercetin
,
Soup
Diseases
:
Cardiovascular Disease: Prevention
,
Cardiovascular Diseases
,
Thrombosis
Pharmacological Actions
:
Anti-thrombotic
,
Cardioprotective
[+]
Prevention of edema in long flights with Pycnogenol.
Jun 30, 2005
Click here to read the entire abstract
Pubmed Data
: Clin Appl Thromb Hemost. 2005 Jul ;11(3):289-94. PMID:
16015414
Article Published Date
: Jun 30, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Leg Edema
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
Prevention of recurrent venous thrombosis and post-thrombotic syndrome.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Minerva Cardioangiol. 2018 Jun ;66(3):238-245. PMID:
29795059
Article Published Date
: May 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Post-Thrombotic Syndrome
,
Venous Thrombosis
[+]
Propolis has radioprotective properties.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Aug;23(8):1159-68. PMID:
19165751
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
,
Flavonoids
,
Polyphenols
Diseases
:
DNA damage
,
Radiation Induced Illness
Pharmacological Actions
:
Radioprotective
[+]
Pycnogenol has antidiabetic action in patients with type 2 diabetes.
Oct 08, 2004
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2004 Oct 8;75(21):2505-13. PMID:
15363656
Article Published Date
: Oct 08, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol has therapeutic value in the prevention of jet lag in healthy and hypertensive patients.
Oct 01, 2008
Click here to read the entire abstract
Pubmed Data
: Minerva Cardioangiol. 2008 Oct;56(5 Suppl):3-9. PMID:
19597404
Article Published Date
: Oct 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Brain Edema
,
Hypertension
,
Jet Lag
Pharmacological Actions
:
Platelet Aggregation Inhibitors
[+]
Pycnogenol improves allergic rhinitis symptoms when supplementation is started at least 5 weeks before the onset of the allergy season.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2010 Aug;24(8):1115-9. PMID:
20549654
Article Published Date
: Aug 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
Anti-Allergic Agents
[+]
Pycnogenol improves diabetes control, lowers cardiovascular disease risk factors, and reduces the need for hypertension medication in type diabetic patients.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2008 May;28(5):315-20. PMID:
19083426
Article Published Date
: May 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Cardiovascular Diseases
,
Diabetes: Cardiovascular Illness
,
Diabetes Mellitus: Type 2
,
Hypertension
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
Additional Keywords
:
Drug Sparing
,
Plant Extracts
[+]
Pycnogenol improves endothelial function of hypertensive patients.
Jan 02, 2004
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2004 Jan 2;74(7):855-62. PMID:
14659974
Article Published Date
: Jan 02, 2004
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Endothelial Dysfunction
,
Hypertension
Pharmacological Actions
:
Platelet Aggregation Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Pycnogenol is effective in treating symptoms associated with menopausal syndrome.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Reprod Med. 2013 Jan-Feb;58(1-2):39-46. PMID:
23447917
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Climacteric
,
Menopausal Syndrome
,
Postmenopausal Disorders: Insomnia
Pharmacological Actions
:
Analgesics
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Pycnogenol may alleviate adverse effects in oncologic treatment, e.g. deep vein thrombosis.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Mol Vis. 2008;14:1288-92. Epub 2008 Jul 10. PMID:
18927527
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Chemotherapy
,
Deep Vein Thrombosis
,
Radiation Induced Illness
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Drug Side Effect Attenuation
[+]
Pycnogenol may be of value in treatment of MSU crystal-induced arthritis through its anti-inflammatory and anti-nitrosative activities.
Feb 14, 2012
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2012 Feb 15 ;52(4):765-74. Epub 2011 Dec 13. PMID:
22198264
Article Published Date
: Feb 14, 2012
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Gout
,
Hyperuricemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Pycnogenol prevents damage in the microcirculation of hypertensive patients, and allows the dose of anti-hypertensive drugs to be reduced in most patients.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Clin Appl Thromb Hemost. 2006 Oct;12(4):440-4. PMID:
17000888
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Edema
,
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
,
Calcium Channel Blockers
,
Platelet Aggregation Inhibitors
Additional Keywords
:
Drug-Plant-Vitamin Synergies
,
Drug Sparing
[+]
Pycnogenol relieves symptoms of tinnitus by improving cochlear flow.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Panminerva Med. 2010 Jun;52(2 Suppl 1):63-7. PMID:
20657537
Article Published Date
: Jun 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Tinnitus
[+]
Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Skin Pharmacol Physiol. 2012 ;25(2):86-92. Epub 2012 Jan 21. PMID:
22270036
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Aging Skin
,
Wrinkles
[+]
Quercetin and rutin may ameliorate insecticide induced oxidative stress in human erythrocytes.
Mar 01, 2010
Click here to read the entire abstract
Pubmed Data
: Toxicol In Vitro. 2010 Mar;24(2):460-4. Epub 2009 Oct 13. PMID:
19833193
Article Published Date
: Mar 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Quercetin
,
Rutin
Diseases
:
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Antioxidants
[+]
Regular consumption of a chocolate rich in flavanols confers significant photoprotection and can thus be effective at protecting human skin from harmful UV effects.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Lett Appl Microbiol. 2009 Sep;49(3):354-60. Epub 2009 Jul 14. PMID:
19735513
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
,
Flavonoids
Diseases
:
Skin Diseases: Photo-Aging
,
Sunburn
[+]
Regular moderate intake of red wine is linked to a better women's sexual health.
Sep 30, 2009
Click here to read the entire abstract
Pubmed Data
: J Sex Med. 2009 Oct ;6(10):2772-7. Epub 2009 Jul 21. PMID:
19627470
Article Published Date
: Sep 30, 2009
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Endothelial Dysfunction
,
Libido: Low
,
Sexaul Dysfunction
[+]
Results showed a direct association between the intake of red wine, a source of stilbenes, and the relative abundance of bacteroides.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Jan ;7(1):104-9. PMID:
26437130
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coffee
,
Flavonoids
,
Red Wine Extract
,
Stilbenes
Diseases
:
Allergic Rhinitis
,
Asthma
[+]
Rheumatoid patients subjectively benefited from the vegan diet rich in antioxidants, lactobacilli and fibre.
Nov 29, 2000
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2000 Nov 30 ;155(1-3):45-53. PMID:
11156742
Article Published Date
: Nov 29, 2000
Study Type
: Human Study
Additional Links
Substances
:
Carotenoids
,
Fiber
,
Flavonoids
,
Lignans
Diseases
:
Inflammation
,
Rheumatoid Arthritis
Therapeutic Actions
:
Dietary Modification: Vegetarian
Pharmacological Actions
:
Antioxidants
[+]
Rooibos tea improves the lipid profile and redox status of adults at risk of developing cardiovascular disease.
Jan 07, 2011
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2011 Jan 7 ;133(1):46-52. Epub 2010 Sep 15. PMID:
20833235
Article Published Date
: Jan 07, 2011
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Rooibos
Diseases
:
Cardiovascular Diseases
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.
Jul 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Microbiol Biotechnol. 2017 Jul 28 ;27(7):1257-1265. PMID:
28535611
Article Published Date
: Jul 27, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Kaempferol
,
Quercetin
,
Sea buckthorn
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Short- and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease.
Jul 10, 2001
Click here to read the entire abstract
Pubmed Data
: Circulation. 2001 Jul 10;104(2):151-6. PMID:
11447078
Article Published Date
: Jul 10, 2001
Study Type
: Human Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
,
Green Tea
,
Tea
Diseases
:
Coronary Artery Disease
,
Endothelial Dysfunction
Pharmacological Actions
:
Antioxidants
,
Vasodilator Agents
Additional Keywords
:
Plant Extracts
[+]
Short-term cocoa consumption signficantly reduces blood cholesterol.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2010 Jul;92(1):218-25. Epub 2010 May 26. PMID:
20504978
Article Published Date
: Jul 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
,
High Cholesterol
Pharmacological Actions
:
Anticholesteremic Agents
[+]
Tea consumption reduces the risk of biliary tract and gallbladder diseases.
Nov 01, 2005
Click here to read the entire abstract
Pubmed Data
: Zhonghua Zhong Liu Za Zhi. 2005 Nov;27(11):667-71. PMID:
16438888
Article Published Date
: Nov 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Green Tea
,
Polyphenols
,
Tea: Black
Diseases
:
Bile Duct Cancer
,
Gallbladder Cancer
Pharmacological Actions
:
Chemopreventive
[+]
The consumption of some flavonoids may interact with exposure to phthalates on the risk of breast cancer.
Oct 31, 2016
Click here to read the entire abstract
Pubmed Data
: Environ Int. 2016 Nov ;96:167-172. Epub 2016 Aug 28. PMID:
27690147
Article Published Date
: Oct 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Vegetables: All
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
Problem Substances
:
Phthalates
[+]
The data support the strategy of flavonoid supplementation to mitigate post-exercise oxidative stress in endurance athletes.
Nov 20, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Sport Nutr Exerc Metab. 2019 Nov 21:1-8. Epub 2019 Nov 21. PMID:
31754080
Article Published Date
: Nov 20, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Athletic Performance: Recovery
,
Oxidative Stress
Therapeutic Actions
:
Exercise: Cycling
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
MicroRNA modulator
,
Nrf2 activation
[+]
The flavonoids hesperidin and diosmin reduce bleeding and pain after stapled hemorrhoidopexy.
Aug 01, 2005
Click here to read the entire abstract
Pubmed Data
: Wien Klin Wochenschr. 2005 Aug;117(15-16):558-60. PMID:
16158207
Article Published Date
: Aug 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Hesperidin
Diseases
:
Hemorrhoids
,
Postoperative Recovery
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
The high intake of flavanol-rich cocoa by the Kuna Indians may be responsible for their low blood pressure.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2006;47 Suppl 2:S103-9; discussion 119-21. PMID:
16794446
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Hypertension
Additional Keywords
:
Proanthocyanidins
[+]
The intake of flavonoids showed an inverse association with risk of cardiovascular events.
Oct 03, 2018
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2018 Oct 4. Epub 2018 Oct 4. PMID:
30459074
Article Published Date
: Oct 03, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Cardiovascular Diseases
Additional Keywords
:
Risk Reduction
[+]
The intake of flavonoids, particularly from solid fruit, is associated with better pulmonary function in patients with COPD.
Jul 01, 2001
Click here to read the entire abstract
Pubmed Data
: Am J Respir Crit Care Med. 2001 Jul 1;164(1):61-4. PMID:
11435239
Article Published Date
: Jul 01, 2001
Study Type
: Human Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Fruit: All
Diseases
:
Chronic Obstructive Pulmonary Disease
[+]
The Mediterranean diet, which includes a combination of antioxidant compounds and flavonoid-rich foods, appears effective to decrease LDL particle oxidizability, which reduces the risk for cardiovascular disease.
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2006 Oct;17(10):645-58. Epub 2006 Feb 3. PMID:
16517144
Article Published Date
: Oct 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Arteriosclerosis
,
Cardiovascular Diseases
,
Cholesterol: Oxidation
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Antioxidants
[+]
The oral intake of Pycnogenol down-regulated the gene expression of various cartilage degradation markers in the patients' chondrocytes.
Dec 15, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Dec 16 ;17(1):537. Epub 2017 Dec 16. PMID:
29246219
Article Published Date
: Dec 15, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]
The present results suggest that high intakes of flavonoids may be associated with decreased risk of ischaemic stroke and possibly with reduced CVD mortality.
Sep 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2008 Oct ;100(4):890-5. Epub 2008 Apr 1. PMID:
18377681
Article Published Date
: Sep 30, 2008
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Cardiac Mortality
,
Cardiovascular Diseases
,
Stroke
Pharmacological Actions
:
Cardioprotective
,
Neuroprotective Agents
Additional Keywords
:
Risk Reduction
[+]
The regular consumption of cocoa products containing flavanols may reduce risk of cardiovascular disease.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Asia Pac J Clin Nutr. 2008;17 Suppl 1:284-7. PMID:
18296357
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cardiovascular Diseases
,
Endothelial Dysfunction
,
Hypertension
Additional Keywords
:
Risk Reduction
[+]
The results of the present study add to the current literature further evidence of the association between higher flavonoid intake and decreased body weight.
Mar 25, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2018 Mar 26:1-10. Epub 2018 Mar 26. PMID:
29575952
Article Published Date
: Mar 25, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
,
Flavonoids
,
obesity
[+]
The risk of lung cancer related to dietary intake of flavonoids.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Cancer. 2012 ;64(7):964-74. PMID:
23061904
Article Published Date
: Dec 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Lung Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Chemopreventive
[+]
These findings suggest a protective association between dietary intake of flavonoids and the likelihood of having age-related macular degeneration.
Jul 05, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2018 Jul 6. Epub 2018 Jul 6. PMID:
29982448
Article Published Date
: Jul 05, 2018
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Orange
Diseases
:
Macular Degeneration
Additional Keywords
:
Risk Reduction
[+]
These findings suggest that the intake of some flavonoids may reduce Parkinson’s disease risk.
Apr 09, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neurology. 2012 Apr 10 ;78(15):1138-45. Epub 2012 Apr 4. PMID:
22491871
Article Published Date
: Apr 09, 2012
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Parkinson's Disease
Additional Keywords
:
Risk Reduction
[+]
These results indicate that flavonoid intake is associated with lower head and neck cancer risk.
Jul 18, 2017
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2017 Jul 19. Epub 2017 Jul 19. PMID:
28724656
Article Published Date
: Jul 18, 2017
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
Diseases
:
Head and Neck Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
This data indicate an inverse association between isoflavones and flavones with respect to bladder cancer risk.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: Cancer Causes Control. 2019 May ;30(5):527-535. Epub 2019 Mar 22. PMID:
30903485
Article Published Date
: Apr 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Isoflavones
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Chemopreventive
[+]
This pilot study provides the first evidence of miRNA modulation by diet and other factors, that can be detected consistently in both plasma and stools samples.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: Mutagenesis. 2014 Sep ;29(5):385-91. PMID:
25150024
Article Published Date
: Aug 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Pharmacological Actions
:
MicroRNA modulator
Additional Keywords
:
Dietary Concentrations
,
Epigenetic Modification
[+]
This study compares the anti-aging potential of ginkgo biloba and topical tea preparations.
Apr 01, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Cosmet Sci. 2010 Apr ;32(2):99-106. PMID:
20412217
Article Published Date
: Apr 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
,
Green Tea
,
Rooibos
Diseases
:
Aging Skin
Additional Keywords
:
Plant Extracts
[+]
This study demonstrates the efficacy of flavonoid rich berries in maintaining or improving cognitive performance.
Nov 05, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Nov 6 ;11(11). Epub 2019 Nov 6. PMID:
31698695
Article Published Date
: Nov 05, 2019
Study Type
: Human Study
Additional Links
Substances
:
Berries: All
,
Blackberry
,
Blueberry
,
Flavonoids
,
Raspberry
,
Strawberry
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
This study indicates that total flavonoids and most flavonoid subclasses intakes were inversely associated with breast cancer risk.
Nov 13, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Cancer Prev. 2019 Nov 14. Epub 2019 Nov 14. PMID:
31738218
Article Published Date
: Nov 13, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Breast Cancer
Pharmacological Actions
:
Chemopreventive
[+]
This study provides evidence for a preventive effect of flavonols on pancreatic cancer.
Oct 14, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Epidemiol. 2007 Oct 15 ;166(8):924-31. Epub 2007 Aug 9. PMID:
17690219
Article Published Date
: Oct 14, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Risk Reduction
[+]
This study provides further support for a beneficial effect of flavonoid intake on lung cancer risk
Jul 31, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Cancer. 2008 Aug 1 ;123(3):664-71. PMID:
18491403
Article Published Date
: Jul 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Flavonoids
,
Isoflavones
Diseases
:
Lung Cancer
,
Smoking
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Proanthocyanidins
[+]
This study provides support for a beneficial effect of selected flavonoids on laryngeal cancer risk.
May 31, 2007
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Oncol. 2007 Jun ;18(6):1104-9. Epub 2007 Mar 19. PMID:
17372161
Article Published Date
: May 31, 2007
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Laryngeal Cancer
Pharmacological Actions
:
Chemopreventive
[+]
Topical diosmin has therapeutic effects in the treatment of acute hemorrhoid pathology.
May 01, 1988
Click here to read the entire abstract
Pubmed Data
: Minerva Med. 1988 May;79(5):387-90. PMID:
3287228
Article Published Date
: May 01, 1988
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
Diseases
:
Hemorrhoids
[+]
Wine consumption reduces TNF-apha-induced adhesion of monocytes to endothelial cells.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2010;26(3):471-82. Epub 2010 Aug 24. PMID:
15213052
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
,
Wine
Diseases
:
Arteriosclerosis
,
Heart Disease: Ischemic
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin highly upregulated the expression of cytokine genes and induced apoptosis in human pancreatic cancer cells.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2013 Dec ;57(12):2112-27. Epub 2013 Aug 14. PMID:
23943362
Article Published Date
: Nov 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Inflammation
,
Pancreatic Cancer
Pharmacological Actions
:
Anti Inflammatory
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Epigenetic Modification In Cancer
[+]
chokeberry juice inhibited Caco-2 cell proliferation by causing G(2)/M cell cycle arrest.
Mar 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2007 Apr ;18(4):259-71. Epub 2006 Jul 24. PMID:
16860979
Article Published Date
: Mar 31, 2007
Study Type
: Human In Vitro
Additional Links
Substances
:
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Chemopreventive
[+]
Flavonoid mixture inhibits Mycobacterium tuberculosis survival and infectivity.
Feb 27, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Feb 28 ;24(5). Epub 2019 Feb 28. PMID:
30823377
Article Published Date
: Feb 27, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Flavonoids
Diseases
:
Mycobacterium tuberculosis
Pharmacological Actions
:
Glutathione Upregulation
,
Immunomodulatory
[+]
Luteolin prevents angiotensin II-induced cardiac remodeling.
Jan 01, 2015
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2015 ;10(9):e0137106. Epub 2015 Sep 1. PMID:
26327560
Article Published Date
: Jan 01, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Flavonoids
,
Luteolin
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
O. majorana and F. vulgare aqueous extracts showed dose and time dependent anti-Blastocystis activity.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2018 Apr 1 ;43:158-163. Epub 2018 Apr 10. PMID:
29747749
Article Published Date
: Mar 31, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Fennel
,
Flavonoids
,
Oregano
Diseases
:
Blastocystis hominis infections
Pharmacological Actions
:
Antioxidants
,
Antiparasitic Agents
Additional Keywords
:
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Curcumin and hesperetin attenuate D-galactose-induced brain senescence in vitro and in vivo
Sep 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res Pract. 2020 Oct ;14(5):438-452. Epub 2020 Aug 6. PMID:
33029285
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
Diseases
:
Neurodegenerative Diseases
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Enhancement of epithelial cell autophagy induced by sinensetin alleviates epithelial barrier dysfunction in colitis.
Jan 09, 2019
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2019 10 ;148:104461. Epub 2019 Sep 19. PMID:
31542404
Article Published Date
: Jan 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
Pharmacological Actions
:
Gastrointestinal Agents
[+]
Optimization of extraction flavonoids from Exocarpium Citri Grandis and evaluation its hypoglycemic and hypolipidemic activities.
Nov 14, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Nov 15 ;262:113178. Epub 2020 Jul 28. PMID:
32736047
Article Published Date
: Nov 14, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Hyperglycemia
,
Hyperlipidemia
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
[+]
Poncirin prevents bone loss in glucocorticoid-induced osteoporosis in vivo and in vitro.
Aug 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Bone Miner Metab. 2012 Sep ;30(5):509-16. Epub 2012 Mar 13. PMID:
22407507
Article Published Date
: Aug 31, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
[+]
"Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats."
Feb 15, 2011
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2011 Feb 15 ;251(1):85-94. Epub 2010 Dec 15. PMID:
21167192
Article Published Date
: Feb 15, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Cancer: Prevention
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Tumor Suppressor Protein p53 Upregulation
[+]
A cocoa diet enhances thymus antioxidant defenses and influences thymocyte differentiation.
Aug 08, 2007
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2007 Aug 8;55(16):6431-8. Epub 2007 Jul 14. PMID:
17630760
Article Published Date
: Aug 08, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
,
Polyphenols
Diseases
:
Low Immune Function: Thymus Dysfunction
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
[+]
A cocoa-enriched diet prevents gingival oxidative stress in experimental periodontitis.
Nov 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2009 Nov;80(11):1799-808. PMID:
19905949
Article Published Date
: Nov 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
,
Polyphenols
Diseases
:
Periodontitis
Pharmacological Actions
:
Antioxidants
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer.
Mar 26, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2019 Mar 27. Epub 2019 Mar 27. PMID:
30919084
Article Published Date
: Mar 26, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot
,
Flavonoids
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Chemopreventive
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
A mixture of phytochemicals naturally present in foods represents a plausible chemopreventive agent for colorectal cancer.
May 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2011 Jun ;4(6):907-15. Epub 2011 Mar 7. PMID:
21383028
Article Published Date
: May 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
,
Apples
,
Flavonoids
Diseases
:
Colon Polyps
,
Colorectal Cancer
,
Colorectal Cancer: Prevention
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
Additional Keywords
:
Dietary Concentrations
[+]
A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions.
Jun 01, 1999
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 1999 Jun;65(3):283-8. PMID:
10404428
Article Published Date
: Jun 01, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Banana
,
Flavonoids
Diseases
:
Aspirin-Induced Toxicity
,
NSAID-induced toxicity
Pharmacological Actions
:
Anti-Ulcer Agents
[+]
A polyphenol extract from red grapes redues fat content in an animal model of non-alcoholic liver disease.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2010 Dec;104(12):1760-70. Epub 2010 Aug 2. PMID:
20673376
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grape
,
Polyphenols
,
Resveratrol
Diseases
:
Fatty Liver
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
A. esculentus flowers protects against transient cerebral ischemia-reperfusion injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:8987173. Epub 2018 Aug 5. PMID:
30174782
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Okra
Diseases
:
Brain Ischemia
,
Cerebral Ischemia
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 inducer
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Nitric Oxide Inhibitor
,
Nrf2 activation
[+]
Acute cocoa flavanol improves cerebral oxygenation without enhancing executive function at rest or after exercise.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Appl Physiol Nutr Metab. 2016 Dec ;41(12):1225-1232. Epub 2016 Aug 5. PMID:
27849355
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Cocoa
,
Flavonoids
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
[+]
Administration of galangin reduced hyperlipidaemia related to the risk of diabetic complications.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2018 Dec ;56(1):302-308. PMID:
29952676
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetic Complications
,
Hyperglycemia
,
Hyperlipidemia
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
[+]
Allomelanins suppress the tumor cell growth in vitro and in vivo.
Aug 01, 1997
Click here to read the entire abstract
Pubmed Data
: Cancer Biother Radiopharm. 1997 Aug;12(4):273-6. PMID:
10851475
Article Published Date
: Aug 01, 1997
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Lymphoma
Pharmacological Actions
:
Cell cycle arrest
Additional Keywords
:
Food Colors: Black
,
Food Colors: Purple
[+]
An aqueous decoction of mango flowers has potential gastroprotective and ulcer-healing properties.
Aug 01, 2004
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2004 Aug;70(8):745-52. PMID:
16500058
Article Published Date
: Aug 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Flowers
,
Mango
,
Polyphenols
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Ulcer Agents
,
Cyclooxygenase Inhibitors
Additional Keywords
:
Plant Extracts
[+]
An extract of aged black garlic significantly suppressed IgE-induced anaphylaxis in a (PCA) model.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2014 Jan ;17(1):92-102. PMID:
24456359
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Garlic: Aged
,
Polyphenols
Diseases
:
Allergies
,
Anaphylaxis
,
IgE-Mediated Hypersensitivity
Pharmacological Actions
:
Anti-Allergic Agents
,
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anthocyanin rich bilberry and blackcurrant diets favorably modulate altered amyloid precursor protein processing and alleviate behavioral abnormalities in a mouse model of AD.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2013 Jan ;24(1):360-70. Epub 2012 Sep 17. PMID:
22995388
Article Published Date
: Dec 31, 2012
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
,
Black Currant
,
Flavonoids
,
Quercetin
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory effects of eriocitrin against the dextran sulfate sodium-induced experimental colitis in murine model.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2019 Nov ;33(11):e22400. Epub 2019 Oct 8. PMID:
31593355
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Colitis
,
Inflammation
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats.
Apr 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2013 May ;51(5):607-13. Epub 2013 Jan 31. PMID:
23363068
Article Published Date
: Apr 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipid Peroxidation
,
Obesity
Pharmacological Actions
:
Antioxidants
,
Enzyme Inhibitors: Pancreatic Lipase
,
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
Anti Therapeutic Actions
:
Western Diet
[+]
Antidepressant activity of flavonoid ethanol extract of Abelmoschus manihot corolla with BDNF up-regulation in the hippocampus.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Yao Xue Xue Bao. 2017 Feb ;52(2):222-8. PMID:
29979503
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Isoquercitrin
,
Okra
,
Quercetin
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Brain-derived neurotrophic factor modulator
Additional Keywords
:
Plant Extracts
[+]
Antitumor and immunomodulatory activities of total flavonoids extract from persimmon leaves in H 22 liver tumor-bearing mice.
Jul 11, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2018 Jul 12 ;8(1):10523. Epub 2018 Jul 12. PMID:
30002398
Article Published Date
: Jul 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Persimmon
Diseases
:
Liver Cancer
Pharmacological Actions
:
Immunomodulatory
,
Interleukin-18 down-regulation
Additional Keywords
:
Plant Extracts
[+]
Antiviral efficacy of flavonoids against enterovirus 71 infection.
Jul 06, 2019
Click here to read the entire abstract
Pubmed Data
: Viruses. 2019 Jul 7 ;11(7). Epub 2019 Jul 7. PMID:
31284698
Article Published Date
: Jul 06, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Kaempferol
,
Luteolin
Diseases
:
Enterovirus 71
Pharmacological Actions
:
Antiviral Agents
[+]
Anxiolytic activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system.
Nov 30, 2008
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2008 Dec ;74(15):1769-73. Epub 2008 Nov 12. PMID:
19006051
Article Published Date
: Nov 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Passion Flower
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Apigenin and myricetin exhibited a protective and promising preventive strategy against cisplatin-induced nephrotoxicity.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):766-774. PMID:
28064632
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
,
Myricetin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Chemoprotective Agents
,
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Apigenin has a protective role against lipid peroxidation and oxidative stress associated with the development of liver cancer in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2009 Dec;207(2):420-7. Epub 2009 May 22. PMID:
15185843
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Apigenin is a bioflavonoid that inhibits hypoxia-activated pathways linked to cancer progression in human prostate cancer
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2008 Sep;47(9):686-700. PMID:
18240292
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Flavonoids
Diseases
:
Hypoxia
,
Prostate Cancer
Pharmacological Actions
:
Vascular Endothelial Growth Factor A Inhibitor
[+]
Apple fibers and polyphenols may play a role in preventing atherosclerosis by decreasing uric acid plasma level.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2007 Apr;14(4):280-4. Epub 2007 Feb 12. PMID:
18558693
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Fiber
,
Flavonoids
,
Polyphenols
Diseases
:
Atherosclerosis
,
Hyperuricemia
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Apple phlorizin attenuates oxidative stress in Drosophila melanogaster.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Mar ;43(3):e12744. Epub 2018 Dec 13. PMID:
31353567
Article Published Date
: Feb 28, 2019
Study Type
: Insect Study
Additional Links
Substances
:
Apple
,
Flavonoids
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Nrf2 activation
[+]
Apple polyphenol extracts prevent damage to human gastric epithelial cells.
Jan 31, 2005
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut. 2005 Feb ;54(2):193-200. PMID:
15647180
Article Published Date
: Jan 31, 2005
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Drug-Induced Toxicity: Indomethacin
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
Additional Keywords
:
Plant Extracts
[+]
Apples may exert their colon cancer protective effects through favorably altering gene patterns resulting in protection of cells against toxicological insults.
Jun 15, 2008
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2008 Jun 15;122(12):2647-55. PMID:
18351577
Article Published Date
: Jun 15, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Colon Cancer
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Epigenetic Modification
[+]
Apples rich polyphenols reduce colonic inflammation in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Dec;102(11):1620-8. Epub 2009 Jul 22. PMID:
19622193
Article Published Date
: Dec 01, 2009
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
Diseases
:
Inflammatory Bowel Diseases
,
Irritable Bowel Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
[+]
Astilbin alleviates lipopolysaccharide -induced acute respiratory distress syndrome.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Jul ;36:51-58. Epub 2016 Apr 22. PMID:
27111514
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astilbin alleviates sepsis-induced acute lung injury.
Sep 30, 2017
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2017 Oct ;40(10):1176-1185. Epub 2017 Aug 24. PMID:
28840536
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lung Injury: Acute
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Astilbin ameliorates cisplatin-induced nephrotoxicity.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Apr ;114:227-236. Epub 2018 Feb 20. PMID:
29471006
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Cyclooxygenase 2 Inhibitors
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astilbin ameliorates experimental autoimmune myasthenia gravis.
Jan 14, 2016
Click here to read the entire abstract
Pubmed Data
: J Neuroimmunol. 2016 09 15 ;298:138-45. Epub 2016 Jul 20. PMID:
27609287
Article Published Date
: Jan 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Myasthenia Gravis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
,
Immunomodulatory: Th17 downregulation
[+]
Astilbin from Smilax glabra attenuates inflammatory responses.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2017 ;2017:8246420. Epub 2017 Aug 22. PMID:
29104606
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Sarsaparilla
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astilbin improves potassium oxonate-induced hyperuricemia and kidney injury.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Oct ;83:975-988. Epub 2016 Aug 11. PMID:
27522260
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Hyperuricemia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Astilbin influences the progression of osteoarthritis in rats by down-regulation of PGE-2 expression via the NF-κB pathway.
May 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Transl Med. 2020 Jun ;8(12):766. PMID:
32647691
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Postaglandin PGE2 downregulation
[+]
Astilbin inhibits Th17 cell differentiation and ameliorates imiquimod-induced psoriasis-like skin lesions.
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Immunopharmacol. 2016 Mar ;32:32-38. Epub 2016 Jan 16. PMID:
26784569
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-17 downregulation
,
Interleukin-2 Downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL‐induced osteoclastogenesis.
Jan 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2019 12 ;23(12):8355-8368. Epub 2019 Oct 11. PMID:
31603626
Article Published Date
: Jan 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
[+]
Astilbin protects chicken peripheral blood lymphocytes from cadmium-induced necroptosis.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Ecotoxicol Environ Saf. 2020 Mar 1 ;190:110064. Epub 2019 Dec 26. PMID:
31838230
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cadmium Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Problem Substances
:
Cadmium
[+]
Astragalin alleviates cerebral ischemia-reperfusion injury by improving anti-oxidant and anti-inflammatory activities.
Apr 20, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2020 Apr 21 ;20(1):120. Epub 2020 Apr 21. PMID:
32316944
Article Published Date
: Apr 20, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Astragalin attenuates oxidative stress and acute inflammatory responses in carrageenan-induced paw edema.
Aug 31, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2020 Sep ;47(9):6611-6620. Epub 2020 Aug 8. PMID:
32770524
Article Published Date
: Aug 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Moringa oleifera
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Astragalin exerted antidepressant-like action through SIRT1 signalling modulated NLRP3 inflammasome deactivation.
Jan 19, 2020
Click here to read the entire abstract
Pubmed Data
: ACS Chem Neurosci. 2020 05 20 ;11(10):1495-1503. Epub 2020 May 4. PMID:
32364698
Article Published Date
: Jan 19, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Moringa oleifera
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Astragalin inhibits nuclear factor-κB signalling in human colonic epithelial cells and attenuates experimental colitis.
May 12, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gut Liver. 2020 May 13. Epub 2020 May 13. PMID:
32390406
Article Published Date
: May 12, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Moringa oleifera
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Astragalin promotes osteoblastic differentiation in MC3T3-E1 cells and bone formation in vivo.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Endocrinol (Lausanne). 2019 ;10:228. Epub 2019 Apr 16. PMID:
31040823
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoporosis
Pharmacological Actions
:
Osteoprotective
[+]
Astragalin reduces hexokinase 2 through increasing miR-125b to inhibit the proliferation of hepatocellular carcinoma cells.
Jul 25, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Jul 26 ;65(29):5961-5972. Epub 2017 Jul 11. PMID:
28654261
Article Published Date
: Jul 25, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
Astragalin reduces lipopolysaccharide-induced acute lung injury in rats via induction of heme oxygenase-1.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2019 Aug ;42(8):704-711. Epub 2019 Jun 27. PMID:
31250343
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Astragalin suppresses inflammatory responses and bone destruction in mice with collagen-induced arthritis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:94. Epub 2019 Feb 12. PMID:
30809149
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragalin-induced cell death is caspase-dependent and enhances the susceptibility of lung cancer cells to tumor necrosis factor.
Apr 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Apr 18 ;8(16):26941-26958. PMID:
28199969
Article Published Date
: Apr 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lung Cancer
Pharmacological Actions
:
Apoptotic
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Baccharis dracunculifolia, the main botanical source of Brazilian green propolis, displays antiulcer activity.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2007 Apr;59(4):603-8. PMID:
17430646
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Baccharis dracunculifolia
,
Bee Propolis
,
Flavonoids
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Ulcer Agents
Additional Keywords
:
Natural Substances Versus Drugs
,
Plant Extracts
[+]
Bamboo leaf flavonoids can effectively improve depression in diabetic rats.
Apr 22, 2019
Click here to read the entire abstract
Pubmed Data
: Zhonghua Yi Xue Za Zhi. 2019 Apr 23 ;99(16):1251-1255. PMID:
31060166
Article Published Date
: Apr 22, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
,
Flavonoids
Diseases
:
Depression
,
Diabetic Complications
Pharmacological Actions
:
Antidepressive Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Banana prevents lipid oxidation in rats.
Dec 01, 2005
Click here to read the entire abstract
Pubmed Data
: Indian J Med Res. 2005 Dec;122(6):540-6. PMID:
16518007
Article Published Date
: Dec 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Banana
,
Flavonoids
,
Plantain
Diseases
:
Cholesterol: Oxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Blackberries improve motor and cognitive performance in aged rats.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2009 Jun;12(3):135-40. PMID:
19356316
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Blackberry
,
Flavonoids
,
Polyphenols
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
[+]
Blue skullcap (S. lateriflora) has anticonvulsant activity.
May 01, 2009
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2009 May;16(5):485-93. Epub 2008 Sep 10. PMID:
18786819
Article Published Date
: May 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Skullcap: Blue
Diseases
:
Convulsions
,
Seizures
Pharmacological Actions
:
Anticonvulsants
Additional Keywords
:
Plant Extracts
[+]
Blueberry inhibits the growth and metastatic potential of triple negative breast cancer in vitro and in vivo.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer Res. 2010 May 1;70(9):3594-605. Epub 2010 Apr 13. PMID:
20388778
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Both curcumin and its metabolite tetrahydrocurcumin exert neuroprotection against chemically-induced neurotoxicity.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2008 Apr;16(2):96-9. PMID:
18408903
Article Published Date
: Apr 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
,
Tetrahydrocurcumin
Diseases
:
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Buckwheat polyphenols protective effect against long-lasting impairment of spatial memory associated with hippocampal neuronal damage in rats subjected to repeated cerebral ischemia.
Apr 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Sci. 2004 Apr;94(4):393-402. PMID:
15107579
Article Published Date
: Apr 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
,
Polyphenols
Diseases
:
Brain Injury: Hippocampal Damage
,
Cerebral Ischemia
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Buckwheat sprouts have an anti-inflammatory effect in lipopolysaccharide-activated human colon cancer cells and mice.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2008 Dec;72(12):3148-57. Epub 2008 Dec 7. PMID:
19060399
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Buckwheat
,
Flavonoids
,
Sprouts
Diseases
:
Colon Cancer
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Plant Extracts
[+]
C. sempervirens and J. phoenicea leaf extracts show a remarkable effect in enhancing liver and kidney functions and may thus be of therapeutic potential in treatment hepatotoxicity and nephrotoxicity.
Dec 06, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastrointest Pharmacol Ther. 2010 Dec 6 ;1(6):123-31. PMID:
21577307
Article Published Date
: Dec 06, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Disease
Therapeutic Actions
:
antioxidant
,
Hepatoprotective
Additional Keywords
:
C. Sempervirens Extract
,
J. Phoenicea Extract
,
Liver Enzymes
,
Plant Extracts
[+]
C. spinosa has the potential to down regulate inflammation-involved genes in Alzheimer's disease.
Oct 24, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2016 Oct 25:1-8. Epub 2016 Aug 25. PMID:
27778760
Article Published Date
: Oct 24, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Capparis spinosa (caper)
,
Flavonoids
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Gene Expression Regulation
[+]
Cacao polyphenol extract suppresses dioxin-induced toxicity in mice.
Jan 01, 1993
Click here to read the entire abstract
Pubmed Data
: Clin Investig. 1993;71(8 Suppl):S134-6. PMID:
18928297
Article Published Date
: Jan 01, 1993
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Dioxin Toxicity
Additional Keywords
:
Plant Extracts
[+]
Celery extract protects against pesticide-induced toxicity.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2011 Nov 1. Epub 2011 Nov 1. PMID:
22045891
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Celery
,
Flavonoids
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide-Induced Toxicity: Organophosphates
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Dichlorvos
,
Organophosphates
,
Pesticides
Adverse Pharmacological Actions
:
Hepatotoxic
,
Oxidant
[+]
Chokeberry fruit derivatives may act as a promising supplementary therapeutic option in the prevention and treatment of disorders occurring in metabolic syndrome, as well as their complications.
Nov 30, 2008
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 2008 Dec ;63(4):176-82. Epub 2008 Aug 23. PMID:
18726160
Article Published Date
: Nov 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Chokeberry
,
Flavonoids
,
Polyphenols
Diseases
:
Diabetes Mellitus: Type 2: Prevention
,
Hyperlipidemia
,
Lipid Peroxidation
,
Metabolic Syndrome X
Pharmacological Actions
:
Alpha-glucosidase inhibitor
,
Hypoglycemic Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Chronic but not acute treatment with the Ginkgo biloba extract EGb 761(R) increased dopaminergic transmission in the rat prefrontal cortex.
Feb 01, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2010 Feb 1 ;159(3):659-68. Epub 2010 Jan 25. PMID:
20105177
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Ginkgo biloba
Diseases
:
Dopamine Deficiency
Pharmacological Actions
:
Dopaminergic
Additional Keywords
:
Plant Extracts
[+]
Citrus flavanones prevent systemic inflammation and ameliorate oxidative stress.
Jun 14, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Jun 15 ;7(6):2675-81. Epub 2016 May 16. PMID:
27182608
Article Published Date
: Jun 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Hesperidin
Diseases
:
C-Reactive Protein
,
High Fat Diet
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Cocoa extract has a neuroprotective action.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2009 Feb;48(1):54-61. Epub 2008 Nov 29. PMID:
19043659
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Neuroblastoma
,
Oxidative Stress
Pharmacological Actions
:
Apoptotic
,
Neuroprotective Agents
[+]
Cocoa extract has a protective efect on experimentally induced benign prostatic hyperplasia.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2007 Dec;10(4):628-35. PMID:
18158833
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Prostatic Hyperplasia: Benign
Additional Keywords
:
Plant Extracts
[+]
Cocoa flavanol and procyanidin supplementation inhibits platelet function.
Jun 01, 2003
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2003 Jun;77(6):1466-73. PMID:
12791625
Article Published Date
: Jun 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
,
Flavonoids
Diseases
:
Clotting
Pharmacological Actions
:
Platelet Aggregation Inhibitors
Additional Keywords
:
Proanthocyanidins
[+]
Cocoa polyphenol has an antidepressant-like effect in rats.
Dec 01, 2008
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2008 Dec;11(6):269-76. PMID:
19000380
Article Published Date
: Dec 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Plant Extracts
[+]
Cocoa polyphenols may inhibit tumor promotion through antioxidant and antiinflammatory mechanisms.
May 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2006 May;136(5):1150-5. PMID:
16614396
Article Published Date
: May 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Polyphenols
Diseases
:
Tumors
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Compounds in oats are bioavailable and act synergistically with vitamin C enhance hamster and human LDL resistance to oxidation.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2004 Jun;134(6):1459-66. PMID:
15173412
Article Published Date
: Jun 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Oats
,
Polyphenols
,
Vitamin C
Diseases
:
Cholesterol: Oxidation
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Natural Substance Synergy
[+]
Consumption of curcumin elevates fecal immunoglobulin A, an index of intestinal immune function, in rats fed a high-fat diet.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Nutr Sci Vitaminol (Tokyo). 2010;56(1):68-71. PMID:
20354349
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
IgA Deficiency
,
Immune Disorders: Low Immune Function
Pharmacological Actions
:
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.
Sep 23, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Sep 23;57(18):8587-90. PMID:
19711910
Article Published Date
: Sep 23, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic Acid
,
Curcumin
,
Ellagic Acid
,
Flavonoids
,
Polyphenols
,
Rutin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
[+]
Corn silk has potential as a therapeutic treatment for diabetic conditions.
Dec 22, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2015 Dec 23 ;21(1):E7. Epub 2015 Dec 23. PMID:
26703560
Article Published Date
: Dec 22, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Corn Silk
,
Flavonoids
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
[+]
Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Funct. 2015 Jun ;33(4):202-10. Epub 2015 May 11. PMID:
25962994
Article Published Date
: May 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cranberry
,
Flavonoids
Diseases
:
Lipid Peroxidation
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Curcumin exhibits chemopreventive properties in hematogenous breast cancer metastases in immunodeficient mice.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2007;19(1-4):137-52. PMID:
17310108
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
Breast Cancer
,
Cancer Metastasis
,
Immune Disorders: Low Immune Function
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Apoptotic
,
NF-kappaB Inhibitor
[+]
Curcuminoids positively modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain.
Nov 01, 2008
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2008 Nov;42(11-12):999-1005. PMID:
19031318
Article Published Date
: Nov 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Flavonoids
,
Polyphenols
Diseases
:
Diabetes: Cognitive Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Cyperus rotundus suppresses AGE formation and protein oxidation in a model of fructose-mediated protein glycoxidation.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2007 Dec 1;41(5):572-8. Epub 2007 Jul 27. PMID:
17765965
Article Published Date
: Dec 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Cyperus rotundus
,
Flavonoids
,
Polyphenols
Diseases
:
Advanced Glycation End products (AGE)
,
Fructose-Induced Toxicity
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Didymin alleviates hepatic fibrosis.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2016 ;40(6):1422-1432. Epub 2016 Dec 20. PMID:
27997902
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Cirrhosis
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Didymin by suppressing NF-κB activation prevents VEGF-induced angiogenesis in vitro and in vivo.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Vascul Pharmacol. 2019 04 ;115:18-25. Epub 2019 Jan 8. PMID:
30634049
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-Angiogenic
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Didymin improves UV irradiation resistance in C. elegans.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PeerJ. 2019 ;6:e6218. Epub 2019 Jan 9. PMID:
30643686
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Photoprotective
[+]
Didymin induces Fas-mediated apoptotic pathway in human non-small-cell lung cancer cells.
May 31, 2010
Click here to read the entire abstract
Pubmed Data
: Lung Cancer. 2010 Jun ;68(3):366-74. Epub 2009 Sep 5. PMID:
19733932
Article Published Date
: May 31, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
,
Tumor Suppressor Protein p53 Upregulation
[+]
Dietary tricin, a flavone present in rice, oats, barley, and wheat inhibits inflammation-related mouse colon carcinogenesis.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila Pa). 2009 Dec;2(12):1031-8. Epub 2009 Nov 24. PMID:
19934339
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Grains: All
,
Oats
,
Rice
,
Tricin
Diseases
:
Colon Cancer
,
Inflammation
Pharmacological Actions
:
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Dietary unripe apple polyphenol inhibits the development of food allergies in the mouse model.
Aug 15, 2005
Click here to read the entire abstract
Pubmed Data
: FEBS Lett. 2005 Aug 15;579(20):4485-91. PMID:
16081068
Article Published Date
: Aug 15, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Apples
,
Flavonoids
,
Polyphenols
,
Tannic Acid
Diseases
:
Food Allergies
Additional Keywords
:
Proanthocyanidins
[+]
Digestion behavior and antidepressant-like effect promoted by acute administration of blueberry extract on mice.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: Food Res Int. 2019 Nov ;125:108618. Epub 2019 Aug 14. PMID:
31554107
Article Published Date
: Oct 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blueberry
,
Flavonoids
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Effect of chrysin on the formation of N-acetyl-p-benzoquinoneimine, a toxic metabolite of paracetamol.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2019 Apr 1 ;302:123-134. Epub 2019 Feb 19. PMID:
30794797
Article Published Date
: Mar 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Milk Thistle
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models.
May 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Fitoterapia. 2014 Jun ;95:83-92. Epub 2014 Mar 2. PMID:
24594241
Article Published Date
: May 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bergamot orange
,
Flavonoids
Diseases
:
Cancer Metastasis
,
Neuroblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
[+]
Effect of lemon seed flavonoids on the anti-fatigue and antioxidant effects of exhausted running exercise.
Feb 02, 2021
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2021 Feb 3:e13620. Epub 2021 Feb 3. PMID:
33533497
Article Published Date
: Feb 02, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Lemon
Diseases
:
Fatigue: Excercise-Induced
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
[+]
Effects of flavonoids and Its derivatives on immune cell responses.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Recent Pat Inflamm Allergy Drug Discov. 2019 ;13(2):84-104. PMID:
31814545
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apigenin
,
EGCG (Epigallocatechin gallate)
,
Flavonoids
,
Quercetin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
,
Interleukin-1 beta downregulation
,
Interleukin-2 Downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Eggplant flavonoids exhibit cholesterol-lowering activity in rats.
Jan 01, 1997
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 1997;51(4):321-30. PMID:
9650725
Article Published Date
: Jan 01, 1997
Study Type
: Animal Study
Additional Links
Substances
:
Eggplant
,
Flavonoids
Diseases
:
Hypercholesterolemia
[+]
Embelia ribes has a cardioprotective effect against isoproterenol-induced myocardial infarcation in rats.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Indian J Exp Biol. 2008 Jan;46(1):35-40. PMID:
18697569
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Embelia ribes
,
Flavonoids
,
Polyphenols
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
Additional Keywords
:
Plant Extracts
[+]
Epicatechin flavonoid compound cause beta cell regeneration. - Article 1
Dec 13, 1982
Click here to read the entire abstract
Pubmed Data
: Life Sci. 1982 Dec 13;31(24):2693-7. PMID:
6759833
Article Published Date
: Dec 13, 1982
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes Mellitus: Type 1
Additional Keywords
:
Beta Cell Regeneration
[+]
Epimedium flavonoids slow immunosenescence via NF-kappaB down-regulation.
Jul 01, 2006
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Jul;26(7):620-4. PMID:
16983917
Article Published Date
: Jul 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Epimedium
,
Flavonoids
Diseases
:
Aging: Immunosenecence
Pharmacological Actions
:
NF-kappaB Inhibitor
[+]
Eriocitrin alleviates oxidative stress and inflammatory response in cerebral ischemia.
May 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Transl Med. 2020 Jun ;8(12):757. PMID:
32647682
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis.
Jan 14, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2014 Jan 15 ;4:3708. Epub 2014 Jan 15. PMID:
24424211
Article Published Date
: Jan 14, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Fatty Liver
,
Hepatic Steatosis
,
Obesity
Pharmacological Actions
:
Hepatoprotective
[+]
Eriocitrin improves adiposity and related metabolic disorders in high-fat diet-induced obese mice.
Feb 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2020 Mar ;23(3):233-241. PMID:
32191577
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Hyperlipidemia
,
Obesity
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Ethanol extract from the leaves of Diospyros kaki may be a potential therapeutic strategy for preventing and treating age-related neurodegenerative diseases.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:8938207. Epub 2018 Dec 23. PMID:
30671176
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Persimmon
Diseases
:
Advanced Glycation End products (AGE)
,
Aging: Brain
,
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Glycation Agents
,
Anti-Inflammatory Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Ethanolic extract of the aerial parts of Passiflora cincinnata reduces nociceptive and inflammatory events in mice.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2018 Aug 1 ;47:58-68. Epub 2018 May 8. PMID:
30166109
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Passion Flower
Diseases
:
Inflammation
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Antinoceceptive
Additional Keywords
:
Plant Extracts
[+]
Evaluation of inhibitory effects of flavonoids on breast cancer resistance protein.
Sep 04, 2019
Click here to read the entire abstract
Pubmed Data
: Toxicol In Vitro. 2019 Sep 5 ;61:104642. Epub 2019 Sep 5. PMID:
31493543
Article Published Date
: Sep 04, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Delphinidin
,
Flavonoids
,
Kaempferol
,
Naringenin
Diseases
:
Breast Cancer
,
Cancers: Drug Resistant
Pharmacological Actions
:
Chemosensitizer
,
Chemotherapeutic
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
,
Chemotherapeutic Synergy: Temozolomide
[+]
Fenugreek (Trigonella foenum graecum) seed polyphenols protects the liver from alcohol toxicity.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Pharmazie. 2007 Apr;62(4):299-304. PMID:
17484288
Article Published Date
: Apr 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Fenugreek
,
Flavonoids
,
Polyphenols
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
Pharmacological Actions
:
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Plant Extracts
[+]
Fig fruit has antioxidant and immunostimulatory properties.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Plant Foods Hum Nutr. 2009 Jun;64(2):167-73. PMID:
19466553
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Fig
,
Flavonoids
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Fisetin alleviates atrial inflammation, remodelling, and vulnerability to atrial fibrillation after myocardial infarction.
Nov 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Heart J. 2019 Nov 30 ;60(6):1398-1406. Epub 2019 Oct 31. PMID:
31666455
Article Published Date
: Nov 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
,
Flavonoids
Diseases
:
Myocardial Fibrosis
,
Myocardial Infarction
Pharmacological Actions
:
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy.
Mar 14, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Mar 15 ;221:83-92. Epub 2019 Feb 8. PMID:
30742869
Article Published Date
: Mar 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
,
Flavonoids
Diseases
:
Cardiomyopathy
,
Diabetic Complications
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
[+]
Fisetin attenuates isoproterenol-induced cardiac ischemic injury.
Mar 14, 2019
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2019 Mar 15 ;56:147-155. Epub 2018 Sep 19. PMID:
30668335
Article Published Date
: Mar 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
,
Flavonoids
Diseases
:
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
NF-kappaB Inhibitor
[+]
Fisetin inhibits pristine-induced systemic lupus erythematosus in a murine model through CXCLs regulation.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2018 Dec ;42(6):3220-3230. Epub 2018 Oct 1. PMID:
30272314
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
,
Flavonoids
Diseases
:
Systemic Lupus Erythematosus
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Fisetin rescues retinal functions by suppressing inflammatory response in a DBA/2J mouse model of glaucoma.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Doc Ophthalmol. 2019 04 ;138(2):125-135. Epub 2019 Feb 11. PMID:
30756213
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fisetin
,
Flavonoids
Diseases
:
Glaucoma
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Flavonoid and stilbene glycoside extracts of fenugreek improved the hyperglycemia in the T2DM mice model.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Animal Model Exp Med. 2018 Mar ;1(1):68-73. Epub 2018 Apr 19. PMID:
30891549
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fenugreek
,
Flavonoids
,
Stilbenes
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
[+]
Flavonoids can restore Brahma functionality by reversing acetylation.
May 28, 2014
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2014 May 29. Epub 2014 May 29. PMID:
24876151
Article Published Date
: May 28, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Rutin
Diseases
:
Cancers: All
,
Lung Cancer
Pharmacological Actions
:
Anti-Tumor
,
Antiproliferative
,
Chemopreventive
Additional Keywords
:
Epigenetic Modification In Cancer
,
Reactivation Of Tumor Suppressor Gene
[+]
Flavonoids could be used as protective agents against oxidative stress induced by gentamicin.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Aug ;118:294-302. Epub 2018 May 26. PMID:
29758313
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Luteolin
Diseases
:
Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions
:
Antioxidants
Problem Substances
:
Gentamicin
[+]
Flavonoids extracted from leaves of Diospyros kaki are potential therapeutic agents for Alzheimer's disease.
May 01, 2018
Click here to read the entire abstract
Pubmed Data
: Neuroreport. 2018 May 2 ;29(7):564-569. PMID:
29481523
Article Published Date
: May 01, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Persimmon
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Flavonoids extracted from mulberry leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes.
Oct 18, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 Oct 19:112326. Epub 2019 Oct 19. PMID:
31639486
Article Published Date
: Oct 18, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
White Mulberry
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Flavonoids from Citrus aurantium ameliorate TNBS-induced ulcerative colitis through protecting colonic mucus layer integrity.
Aug 14, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 Aug 15 ;857:172456. Epub 2019 Jun 17. PMID:
31220438
Article Published Date
: Aug 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Orange
,
Flavonoids
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastroprotective
[+]
Flavonoids from Houttuynia cordata attenuate H1N1-induced acute lung injury in mice via inhibition of influenza virus and Toll-like receptor signalling.
Dec 15, 2019
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2019 Dec 16 ;67:153150. Epub 2019 Dec 16. PMID:
31958713
Article Published Date
: Dec 15, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Influenza
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Flavonoids may act as a prenatal preventive against increased interleukin-6 mediated maternal immune activiation associated with abnormal social interactions in adult offspring.
Dec 10, 2009
Click here to read the entire abstract
Pubmed Data
: J Neuroimmunol. 2009 Dec 10;217(1-2):20-7. Epub 2009 Sep 18. PMID:
19766327
Article Published Date
: Dec 10, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
,
Flavonoids
,
Luteolin
Diseases
:
Autism
,
Prenatal Nutrition: Health of the Offspring
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Flavonoids of Rosa roxburghii Tratt offers protection against radiation induced apoptosis and inflammation in mouse thymus.
Jan 09, 2018
Click here to read the entire abstract
Pubmed Data
: Apoptosis. 2018 10 ;23(9-10):470-483. PMID:
29995207
Article Published Date
: Jan 09, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
,
Rose
Diseases
:
Inflammation
,
Radiation Induced Illness
Pharmacological Actions
:
Anti-Apoptotic
,
NF-kappaB Inhibitor
,
Radioprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Flavopiridol and paclitaxel exerted synergistic cytotoxic activities against SKOV3 cells in vitro and significantly suppress the tumor growth of mice bearing SKOV3 cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Arch Gynecol Obstet. 2015 Jan ;291(1):143-50. Epub 2014 Aug 14. PMID:
25118834
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Chemothapeutic Synergy: Paclitaxel
[+]
French maritime pine tree bark extract improves sperm quality and function.
Oct 01, 2002
Click here to read the entire abstract
Pubmed Data
: J Reprod Med. 2002 Oct;47(10):821-4. PMID:
12418064
Article Published Date
: Oct 01, 2002
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
,
Pycnogenol (Pine Bark)
Diseases
:
Infertility: Male
,
Sperm Quality: Low
Pharmacological Actions
:
Antioxidants
[+]
Galangin alleviates liver ischemia-reperfusion injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;51(3):1354-1363. Epub 2018 Nov 27. PMID:
30481779
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Liver Injury: Ischemia/reperfusion
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Galangin ameliorated pulmonary fibrosis in vivo and in vitro by regulating epithelial-mesenchymal transition.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Bioorg Med Chem. 2020 Oct 1 ;28(19):115663. Epub 2020 Jul 28. PMID:
32912432
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Pulmonary Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
[+]
Galangin ameliorates cardiac remodeling via the MEK1/2-ERK1/2 and PI3K-AKT pathways.
Feb 10, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Physiol. 2019 Feb 11. Epub 2019 Feb 11. PMID:
30741414
Article Published Date
: Feb 10, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Heart Failure
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
[+]
Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death.
Jan 14, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2017 08 15 ;329:128-139. Epub 2017 May 27. PMID:
28558962
Article Published Date
: Jan 14, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
Galangin attenuated cerebral ischemia-reperfusion injury.
Oct 27, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Oct 28:118660. Epub 2020 Oct 28. PMID:
33127512
Article Published Date
: Oct 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Galangin could be a beneficial anti-allergic inflammatory agent.
Jun 30, 2013
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2013 Jul ;57:209-16. Epub 2013 Mar 25. PMID:
23535185
Article Published Date
: Jun 30, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Anaphylaxis
,
Asthma
,
Atopic Dermatitis
,
IgE-Mediated Hypersensitivity
,
Inflammation
,
Sinusitis
Pharmacological Actions
:
Anti-Allergic Agents
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
Galangin has a role in protecting dopaminergic neurons by inhibiting microglial activation.
Dec 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Dec 21 ;19(1). Epub 2017 Dec 21. PMID:
29267220
Article Published Date
: Dec 20, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Galangin improved non-alcoholic fatty liver Disease in mice by promoting autophagy.
Dec 31, 2019