Fucoxanthin

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24 Diseases Researched for Fucoxanthin
NameACCKFocus
Obesity47Locked
Sunburn15Locked
Ultraviolet Radiation Induced Damage15Locked
Diabetes Mellitus: Type 224Locked
Liver Cancer33Locked
Alzheimer's Disease12Locked
Brain Injury: Traumatic12Locked
Cancers: All22Locked
Colon Cancer12Locked
Hyperglycemia12Locked
Inflammation12Locked
Overweight 12Locked
Prostate Cancer22Locked
Brain Inflammation 11Locked
Cancer Metastasis11Locked
Cancers: Drug Resistant11Locked
Cancers: Multi-Drug Resistant11Locked
Cardiovascular Diseases11Locked
Hepatoma11Locked
Hydrogen Peroxide Induced Toxicity11Locked
Hyperlipidemia11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Metabolic Syndrome X11Locked
Neurodegenerative Diseases11Locked
22 Pharmacological Actions Researched for Fucoxanthin
NameACCKFocus
Neuroprotective Agents46Locked
Anti-Inflammatory Agents35Locked
Antiproliferative 45Locked
Photoprotective15Locked
Cell cycle arrest44Locked
Anticarcinogenic Agents23Locked
Antioxidants23Locked
Cyclooxygenase 2 Inhibitors23Locked
Interleukin-6 Downregulation23Locked
NF-kappaB Inhibitor23Locked
Nrf2 activation23Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor23Locked
Antineoplastic Agents22Locked
Apoptotic22Locked
Hypoglycemic Agents12Locked
Anti-Angiogenic11Locked
Anti-Apoptotic11Locked
Cardioprotective11Locked
Chemosensitizer11Locked
Heme oxygenase-1 up-regulation11Locked
Hypolipidemic11Locked
Multidrug Resistance Gene Modulators11Locked
Related Topics

Fucoxanthin is a Sub of the following Topic

View the Evidence:
65 Abstracts with Fucoxanthin Research

[+]

Fucoxanthin activates apoptosis and suppresses invasion and migration glioblastoma cells.Sep 30, 2016

Pubmed Data : Neurochem Res. 2016 Oct ;41(10):2728-2751. Epub 2016 Jul 9. PMID: 27394418
Article Published Date : Sep 30, 2016
Study Type : Human In Vitro
Additional Links
Substances : Fucoxanthin
Diseases : Glioblastoma
Pharmacological Actions : Anti-metastatic, Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Fucoxanthin exerted a protective effect against UV irradiation.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2016 Sep ;132(1):55-64. Epub 2016 Aug 12. PMID: 27590588
Article Published Date : Aug 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Fucoxanthin
Diseases : Sunburn, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective
[+]

Anti-inflammatory and apoptotic signalling effect of fucoxanthin on benzo(A)pyrene-induced lung cancer.Dec 31, 2018

Pubmed Data : J Environ Pathol Toxicol Oncol. 2019 ;38(3):239-251. PMID: 31679311
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Benzo[a]pyrene-induced Toxicity , Lung Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Chemopreventive
Problem Substances : Benzo(a)pyrene
[+]

Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic mice.Aug 06, 2008

Pubmed Data : Forensic Sci Int. 2008 Aug 6;179(2-3):e25-9. Epub 2008 Jun 6. PMID: 17715888
Article Published Date : Aug 06, 2008
Study Type : Animal Study
Additional Links
Substances : Fish Oil, Fucoxanthin
Diseases : Diabetes Mellitus: Type 2, Obesity
Additional Keywords : Natural Substance Synergy
[+]

Fucoidan and fucoxanthin in combination can potentially reduce cardiac hypertrophy, cardiac fibrosis, ROS level,Jan 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Jan 21 ;17(1). Epub 2019 Jan 21. PMID: 30669571
Article Published Date : Jan 20, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoidan, Fucoxanthin
Diseases : Aging: Heart, Cardiac Hypertrophy, Myocardial Fibrosis
Pharmacological Actions : Antioxidants, Cardioprotective
[+]

Fucoxanthin could be a novel adjuvant for preventing exacerbations associated with skin inflammation as well as protecting skin against UV radiation.Oct 09, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2018 Oct 10 ;16(10). Epub 2018 Oct 10. PMID: 30308980
Article Published Date : Oct 09, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Erythema, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-6 Downregulation, Nrf2 activation, Photoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoxanthin could be exploited as a therapeutic target for protecting neurons from cerebral ischemic/reperfusion injury.Sep 30, 2018

Pubmed Data : Biomed Pharmacother. 2018 Oct ;106:1484-1489. Epub 2018 Jul 24. PMID: 30119223
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Cerebral Ischemia
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Fucoxanthin exhibits anti-obesity properties.Dec 01, 2009

Pubmed Data : Mol Nutr Food Res. 2009 Dec;53(12):1603-11. PMID: 19842104
Article Published Date : Dec 01, 2009
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents
[+]

Fucoxanthin had anti-inflammatory effects in a model of sepsis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:906. Epub 2019 Aug 28. PMID: 31555126
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Inflammation, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoxanthin inhibits profibrotic protein expression in vitro and attenuates bleomycin-induced lung fibrosis in vivo.Sep 14, 2017

Pubmed Data : Eur J Pharmacol. 2017 Sep 15 ;811:199-207. Epub 2017 Jun 19. PMID: 28642129
Article Published Date : Sep 14, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic
[+]

Fucoxanthin inhibits tumour-related lymphangiogenesis and growth of breast cancer.Jan 15, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Jan 16. Epub 2019 Jan 16. PMID: 30648805
Article Published Date : Jan 15, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Chemotherapeutic, Vascular Endothelial Growth Factor C Inhibitor
[+]

Fucoxanthin inhibits β-amyloid assembly and attenuates β-amyloid oligomer-induced cognitive impairments.May 23, 2017

Pubmed Data : J Agric Food Chem. 2017 May 24 ;65(20):4092-4102. Epub 2017 May 11. PMID: 28478680
Article Published Date : May 23, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

fucoxanthin is a potential D3/D4 agonist for the management of neurodegenerative diseases.Jul 15, 2019

Pubmed Data : Chem Biol Interact. 2019 Jul 16 ;310:108757. Epub 2019 Jul 16. PMID: 31323226
Article Published Date : Jul 15, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Fucoxanthin is a potential nutraceutical for preventing alcohol-induced liver injury.Sep 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Sep 27 ;17(10). Epub 2019 Sep 27. PMID: 31569771
Article Published Date : Sep 26, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, NF-kappaB Inhibitor, Nrf2 activation
[+]

Fucoxanthin may have therapeutic potential as a treatment for patients with inflammatory diseases.Sep 28, 2015

Pubmed Data : J Biochem Mol Toxicol. 2015 Sep 29. Epub 2015 Sep 29. PMID: 26418808
Article Published Date : Sep 28, 2015
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
[+]

Fucoxanthin may serve as a chemotherapeutic agent against liver cancer.Oct 30, 2018

Pubmed Data : Drug Dev Res. 2018 Oct 31. Epub 2018 Oct 31. PMID: 30379338
Article Published Date : Oct 30, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Liver Cancer
Pharmacological Actions : Chemopreventive, Chemotherapeutic
[+]

Fucoxanthin might exhibit great therapeutic efficacy for the treatment of Alzheimer's disease.Mar 24, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2016 Mar 25 ;14(4). Epub 2016 Mar 25. PMID: 27023569
Article Published Date : Mar 24, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Fucoxanthin modulates cecal and fecal microbiota differently based on diet.Aug 31, 2019

Pubmed Data : Food Funct. 2019 Sep 1 ;10(9):5644-5655. Epub 2019 Aug 21. PMID: 31433413
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Gastrointestinal Agents
[+]

Fucoxanthin potentiates anoikis in colon mucosa and prevents carcinogenesis in AOM/DSS model mice.Jan 31, 2019

Pubmed Data : J Nutr Biochem. 2019 Feb ;64:198-205. Epub 2018 Oct 25. PMID: 30530259
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
[+]

Fucoxanthin prevents lipopolysaccharide-induced depressive-like behavior in mice.Dec 14, 2018

Pubmed Data : Metab Brain Dis. 2018 Dec 15. Epub 2018 Dec 15. PMID: 30554399
Article Published Date : Dec 14, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Depression, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoxanthin provides a limited reduction in alveolar bone resorption in rats with periodontitis.Mar 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2016 Mar 30 ;14(4). Epub 2016 Mar 30. PMID: 27043583
Article Published Date : Mar 29, 2016
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Oxidative Stress, Periodontitis
Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoxanthin provides neuroprotection in models of traumatic brain injury.Apr 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Apr 21 ;7:46763. Epub 2017 Apr 21. PMID: 28429775
Article Published Date : Apr 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
Additional Keywords : Antioxidants, Brain Injury: Traumatic, Fucoxanthin, Neuroprotective Agents, Nrf2 activation
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fucoxanthin showed effective anti-asthma activity against ovalbumin-induced asthma.Dec 31, 2018

Pubmed Data : J Environ Pathol Toxicol Oncol. 2019 ;38(3):229-238. PMID: 31679310
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents, Anti-Inflammatory Agents
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Fucoxanthin supplementation improves plasma and hepatic lipid metabolism and blood glucose concentration in high-fat fed mice.Apr 01, 2002

Pubmed Data : J Neurochem. 2002 Apr;81(1):194-202. PMID: 20519145
Article Published Date : Apr 01, 2002
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Hyperglycemia, Obesity
Additional Keywords : High-Fat Diet, Plant Extracts
[+]

Fucoxanthin, lutein and tetrahydrocurcumin may have chemopreventive effects against colon carcinogenesis.Jan 01, 1998

Pubmed Data : Carcinogenesis. 1998 Jan;19(1):81-5. PMID: 9472697
Article Published Date : Jan 01, 1998
Study Type : Animal Study
Additional Links
Substances : Carotenoids, Curcumin, Fucoxanthin , Lutein, Tetrahydrocurcumin
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative
[+]

Fucoxanthin-rich brown algae extract improves male reproductive function in a diabetes model.Sep 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Sep 11 ;20(18). Epub 2019 Sep 11. PMID: 31514311
Article Published Date : Sep 10, 2019
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Diabetic Complications, Infertility: Male
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Fucoxanthin-rich seaweed extract suppresses body weight gain and improves lipid metabolism in high-fat-fed mice.Sep 01, 2010

Pubmed Data : Biotechnol J. 2010 Sep;5(9):961-9. PMID: 20845386
Article Published Date : Sep 01, 2010
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin , Seaweed: Brown
Diseases : Overweight
Additional Keywords : High-Fat Diet
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Low-molecular-weight fucoidan and fucoxanthin supplementation exerts a beneficial effect on hepatic glucose levels and glucose homeostasis.Apr 06, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2017 Apr 7 ;15(4). Epub 2017 Apr 7. PMID: 28387741
Article Published Date : Apr 06, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoidan, Fucoxanthin
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Diabetes mellitus: Type 2, Fucoidan, Fucoxanthin, Hypoglycemic Agents
[+]

Pretreatment with fucoxanthin may protect against UVB radiation-induced corneal disorders.Jan 06, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2016 Jan 7 ;14(1):13. Epub 2016 Jan 7. PMID: 26751458
Article Published Date : Jan 06, 2016
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin , Seaweed
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Photoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
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The in vivo experiment also confirmed the superiority of fucoxanthin than lutein in protecting retina against photoinduced damage. Jan 19, 2016

Pubmed Data : J Agric Food Chem. 2016 Jan 20 ;64(2):416-24. Epub 2016 Jan 4. PMID: 26708928
Article Published Date : Jan 19, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Eye Damage, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

These finding suggested that the use of fucoxanthin provides a new and attractive alternative to control ulcerative colitis.Nov 28, 2018

Pubmed Data : Nat Prod Res. 2018 Nov 29:1-5. Epub 2018 Nov 29. PMID: 30488724
Article Published Date : Nov 28, 2018
Study Type : Animal Study
Additional Links
Substances : Fucoxanthin
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor
[+]

These results indicate the potential health-promoting effects of fucoxanthin in skin cancer prevention.Jan 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AAPS J. 2018 02 20 ;20(2):32. Epub 2018 Feb 20. PMID: 29603113
Article Published Date : Jan 19, 2018
Study Type : Animal Study
Additional Links
Substances : Astaxanthin, Fucoxanthin
Diseases : Skin Cancer
Pharmacological Actions : Antioxidants, Chemopreventive, Nrf2 activation
Additional Keywords : Epigenetic Modification In Cancer
[+]

Anticancer effects of seaweed compound fucoxanthin alone and in combination with 5-fluorouracil in colon cells.Aug 28, 2017

Pubmed Data : J Toxicol Environ Health A. 2017 Aug 29:1-12. Epub 2017 Aug 29. PMID: 28850007
Article Published Date : Aug 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil
[+]

Effects of fucoxanthin on autophagy and apoptosis in SGC-7901cells and the mechanism.Aug 31, 2018

Pubmed Data : J Cell Biochem. 2018 Sep ;119(9):7274-7284. Epub 2018 May 15. PMID: 29761894
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Gastric Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Fucoxanthin and neoxanthin induce apoptosis in human prostate cancer cells.Dec 01, 2001

Pubmed Data : J Nutr. 2001 Dec;131(12):3303-6. PMID: 11739884
Article Published Date : Dec 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin , Green Leafy Vegetables, Neoxanthin , Seaweed: Brown
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic
[+]

Fucoxanthin and TRAIL increased the apoptosis in human cervical cancer cells.Dec 31, 2017

Pubmed Data : Med Sci Monit. 2018 Jan 1 ;24:11-18. Epub 2018 Jan 1. PMID: 29291370
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic
[+]

Fucoxanthin attenuates fatty acid-induced lipid accumulation in FL83B hepatocytes.Dec 31, 2017

Pubmed Data : Biochem Biophys Res Commun. 2018 01 1 ;495(1):197-203. Epub 2017 Nov 4. PMID: 29113798
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Fatty Liver
Pharmacological Actions : Hepatoprotective, Hypolipidemic
Additional Keywords : Anti-Obesity Agents
[+]

Fucoxanthin combined with other drugs could enhance the effect of both fucoxanthin and the other drug or reduce the dose without reducing the effect.Jan 08, 2019

Pubmed Data : J Cancer Res Clin Oncol. 2019 Jan 9. Epub 2019 Jan 9. PMID: 30627824
Article Published Date : Jan 08, 2019
Study Type : Review
Additional Links
Substances : Fucoxanthin
Diseases : Cancers: All
Pharmacological Actions : Anti-Angiogenic, Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemothapeutic Synergy: Imatinib
[+]

Fucoxanthin demonstrates anti-angiogenic activity. Dec 01, 2001

Pubmed Data : J Nutr. 2001 Dec;131(12):3303-6. PMID: 17177505
Article Published Date : Dec 01, 2001
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Cancer Metastasis
Pharmacological Actions : Anti-Angiogenic
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Fucoxanthin exerts anti-fibrogenic effects in hepatic stellate cells.Apr 10, 2019

Pubmed Data : Biochem Biophys Res Commun. 2019 Apr 11. Epub 2019 Apr 11. PMID: 30982574
Article Published Date : Apr 10, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic
Additional Keywords : Gene Expression Regulation
[+]

Fucoxanthin has anti-neuroinflammatory effects.Jan 31, 2017

Pubmed Data : Neurochem Res. 2017 Feb ;42(2):667-677. Epub 2016 Dec 8. PMID: 27933547
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fucoxanthin induces apoptosis in human glioma cells.Jan 27, 2019

Pubmed Data : J Agric Food Chem. 2019 Jan 28. Epub 2019 Jan 28. PMID: 30688446
Article Published Date : Jan 27, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Glioma
Pharmacological Actions : Apoptotic, Chemotherapeutic
[+]

Fucoxanthin inhibitis the growth of human hepatic carcinoma cells. Apr 01, 2008

Pubmed Data : Biochim Biophys Acta. 2008 Apr ;1780(4):743-9. Epub 2008 Jan 12. PMID: 18230364
Article Published Date : Apr 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Hepatoma, Liver Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Fucoxanthin inhibits human liver and prostate cancer cell growth.Mar 01, 2007

Pubmed Data : In Vivo. 2007 Mar-Apr;21(2):305-9. PMID: 17436581
Article Published Date : Mar 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Liver Cancer, Prostate Cancer
Pharmacological Actions : Cell cycle arrest
[+]

Fucoxanthin inhibits lipid accumulation and ROS production.Oct 31, 2016

Pubmed Data : Phytother Res. 2016 Nov ;30(11):1802-1808. Epub 2016 Jul 13. PMID: 27406217
Article Published Date : Oct 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Hyperlipidemia
Pharmacological Actions : Antioxidants, Hypolipidemic
[+]

Fucoxanthin inhibits the proliferation of a hepatoma cell line.Dec 10, 2009

Pubmed Data : Chem Biol Interact. 2009 Dec 10 ;182(2-3):165-72. Epub 2009 Sep 6. PMID: 19737546
Article Published Date : Dec 10, 2009
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Liver Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Cell cycle arrest
[+]

Fucoxanthin is a potential therapeutic strategy for diabetic nephropathy.Dec 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Dec 12 ;17(12). Epub 2019 Dec 12. PMID: 31842414
Article Published Date : Dec 11, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Diabetic Nephropathy, Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Antioxidants
[+]

Fucoxanthin may enhance the conversion of ALA to longer chain n-3 PUFA through increasing delta-5 desaturase activity in the liver.Sep 30, 2015

Pubmed Data : Lipids. 2015 Oct ;50(10):945-53. Epub 2015 Aug 14. PMID: 26271617
Article Published Date : Sep 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : ALA (Alpha-Linolenic Acid), Fucoxanthin
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Fucoxanthin prevents H2O2-induced neuronal apoptosis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2017 ;61(1):1304678. Epub 2017 Mar 28. PMID: 28469544
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Fucoxanthin-An antibacterial carotenoid.Jul 23, 2019

Pubmed Data : Antioxidants (Basel). 2019 Jul 24 ;8(8). Epub 2019 Jul 24. PMID: 31344844
Article Published Date : Jul 23, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Staphylococcus aureus infection, Staphylococcus epidermidis
Pharmacological Actions : Anti-Bacterial Agents
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Fucoxanthinol could be used as a chemopreventive agent against human colorectal cancer stem cells.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2017 Jul ;61(1):25-32. Epub 2017 May 16. PMID: 28751806
Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Colon Cancer
Pharmacological Actions : Chemopreventive
Additional Keywords : Cancer Stem Cells
[+]

In this review, the mechanisms by which fucoxanthin exerts its antitumor and cancer-preventative action in cell lines and mouse models is discussed.Dec 31, 2016

Pubmed Data : Anticancer Res. 2017 04 ;37(4):1557-1562. PMID: 28373414
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Fucoxanthin
Diseases : Cancers: All
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Cell cycle arrest
[+]

In this review, they have summarized the recent progress on dietary nutraceuticals in reversing multidrug resistance.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(16):6831-9. PMID: 26514453
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : beta-Carotene, Bitter Melon, Capsaicin, Curcumin, EGCG (Epigallocatechin gallate), Fruit: All, Fucoxanthin , Gingerol , Grape Seed Extract, Indole-3-Carbinol, Piperine, Quercetin, Resveratrol, Vegetables: All
Diseases : Cancers: All
Pharmacological Actions : Multidrug Resistance Gene Modulators
Additional Keywords : Multidrug Resistance, Natural Substance/Drug Synergy
[+]

Low-dose doxorubicin with carotenoids selectively alters redox status and upregulates oxidative stress-mediated apoptosis in breast cancer cells.Jul 31, 2018

Pubmed Data : Food Chem Toxicol. 2018 Aug ;118:675-690. Epub 2018 Jun 18. PMID: 29920287
Article Published Date : Jul 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin, beta-Carotene, Carotenoids, Fucoxanthin , Lutein
Diseases : Breast Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin, Selective Cytotoxicity
[+]

Marine carotenoid fucoxanthin possesses anti-Metastasis activity.Jun 04, 2019

Pubmed Data : Mar Drugs. 2019 Jun 5 ;17(6). Epub 2019 Jun 5. PMID: 31195739
Article Published Date : Jun 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Cancers: All
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Marine carotenoids have a beneficial affect on cardiovascular risk markers.Jan 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2011 ;9(7):1166-75. Epub 2011 Jun 27. PMID: 21822408
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Substances : Astaxanthin, Fucoxanthin
Diseases : Cardiovascular Diseases
Pharmacological Actions : Cardioprotective
[+]

Sensitization of TRAIL-resistant cervical cancer cells through combination of TRAIL and fucoxanthin treatments.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2017 Dec ;21(24):5594-5601. PMID: 29271991
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Cervical Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
[+]

The brown seaweed carotenoid, fucoxanthin, is a multi-functional nutrient which may have a therapeutic role in treating metabolic syndrome.Jun 01, 2009

Pubmed Data : Immunopharmacol Immunotoxicol. 2009 Jun;31(2):314-9. PMID: 18296336
Article Published Date : Jun 01, 2009
Study Type : Review
Additional Links
Substances : Carotenoids, Fucoxanthin , Seaweed: Brown
Diseases : Metabolic Syndrome X, Obesity
[+]

The results demonstrated that both astaxanthin and fucoxanthin exhibited multi-neuroprotective effects.Jan 08, 2019

Pubmed Data : Neurochem Int. 2019 Jan 9 ;124:215-224. Epub 2019 Jan 9. PMID: 30639263
Article Published Date : Jan 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin, Fucoxanthin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

The results suggest that fucoxanthin exerts cytoprotective effects against H2O2-induced oxidative damage in L02 cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:1085073. Epub 2018 Nov 15. PMID: 30581841
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Cytoprotective, Nrf2 activation
[+]

These results suggest that this combination of natural products exerts photo-protective effects.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2019 Aug 1 ;17(8). Epub 2019 Aug 1. PMID: 31374828
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin , Rosemaric Acid
Diseases : Inflammation, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Photoprotective
[+]

These results suggested that fucoxanthin and fucoxanthinol may be of use as chemotherapeutic agents in colorectal cancer.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2015 Sep ;10(3):1463-1467. Epub 2015 Jun 16. PMID: 26622691
Article Published Date : Aug 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Colorectal Cancer
Pharmacological Actions : Chemopreventive
[+]

These results suggested that fucoxanthin might prevent Aβ oligomer-induced neuronal loss and oxidative stress.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:6792543. Epub 2017 Aug 8. PMID: 28928905
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

This review summarizes the protective action of carotenoids against the development and progression of NAFLD.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Prev Nutr Food Sci. 2019 Jun ;24(2):103-113. Epub 2019 Jun 30. PMID: 31328113
Article Published Date : May 31, 2019
Study Type : Review
Additional Links
Substances : Astaxanthin, B-Carotene, Crocetin, Cryptoxanthin, Fucoxanthin , Lutein, Lycopene
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective
[+]

This study implies that carotenoids may be utilised as chemosensitisers.Aug 14, 2012

Pubmed Data : Phytomedicine. 2012 Aug 15 ;19(11):977-87. Epub 2012 Jul 4. PMID: 22770743
Article Published Date : Aug 14, 2012
Study Type : In Vitro Study
Additional Links
Substances : beta-Carotene, Canthaxanthin, Crocin, Fucoxanthin
Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Chemothapeutic Synergy: Vinblastine

Copyright: imagezebra / 123RF Stock Photo

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