Fucoxanthin

Name	AC	CK
Obesity	8	14
Nonalcoholic fatty liver disease (NAFLD)	3	13
Ultraviolet Radiation Induced Damage	4	10
Inflammation	6	9
Cancers: All	8	8
Colorectal Cancer	4	6
Glioblastoma	2	6
High Fat Diet	3	6
Alzheimer's Disease	4	5
Colon Cancer	3	5
Diabetes Mellitus: Type 2	3	5
Diabetic Retinopathy	1	5
Lipopolysaccharide-Induced Toxicity	4	5
Liver Cancer	4	5
Oxidative Stress	3	5
Sunburn	1	5
Hyperglycemia	2	4
Neurodegenerative Diseases	3	4
Breast Cancer	2	3
Cervical Cancer	3	3
Lung Cancer	2	3
Parkinson's Disease	2	3
Aging: Heart	1	2
Air Pollution Linked Toxicity	1	2
Alcoholic Liver Disease	1	2
Asthma	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Brain Inflammation	2	2
Brain Injury: Traumatic	1	2
Breast Cancer: Triple Negative	1	2
Cadmium Poisoning	1	2
Cancers: Drug Resistant	2	2
Cancers: Multi-Drug Resistant	2	2
Cardiac Hypertrophy	1	2
Cerebral Ischemia	1	2
Chemotherapy-Induced Toxicity: Cisplatin	1	2
Chronic Kidney Disease (CKD)	1	2
Cognitive Decline/Dysfunction	1	2
Colitis	1	2
Depression	1	2
Diabetic Complications	1	2
Dysbiosis	1	2
Erythema	1	2
Eye Damage	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Hypothyroidism	1	2
Infertility: Male	1	2
Insulin Resistance	1	2
Macular Degeneration	1	2
Myocardial Fibrosis	1	2
Overweight	1	2
Periodontitis	1	2
Prostate Cancer	2	2
Pulmonary Fibrosis: Bleomycin-Induced	1	2
Sepsis	1	2
Skin Cancer	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Atopic Dermatitis	1	1
Cancer Metastasis	1	1
Cardiovascular Diseases	1	1
Chronic Disease	1	1
Diabetic Nephropathy	1	1
Fatty Liver	1	1
Gastric Cancer	1	1
Glioma	1	1
Hepatoma	1	1
Hyperlipidemia	1	1
Kidney Fibrosis	1	1
Liver Damage	1	1
Liver Fibrosis	1	1
Lung Injury: Acute	1	1
Metabolic Syndrome X	1	1
Nasopharyngeal Cancer	1	1
Osteoporosis	1	1
Rheumatoid Arthritis	1	1
Staphylococcus aureus infection	1	1
Staphylococcus epidermidis	1	1
Subarachnoid hemorrhage	1	1

Name	AC	CK
Anti-Inflammatory Agents	25	50
Antioxidants	21	36
Interleukin-6 Downregulation	10	25
Apoptotic	16	22
Antiproliferative	14	19
Hepatoprotective	5	16
Neuroprotective Agents	11	16
Chemopreventive	9	15
Nrf2 activation	9	14
Tumor Necrosis Factor (TNF) Alpha Inhibitor	8	14
Cyclooxygenase 2 Inhibitors	6	11
Anti-Apoptotic	5	10
Interferon Gamma Reducer	1	10
Interleukin-1 beta downregulation	6	10
Photoprotective	4	10
Anti-metastatic	4	8
NF-kappaB Inhibitor	5	8
Anticarcinogenic Agents	4	7
Antineoplastic Agents	3	7
Chemotherapeutic	5	7
Cell cycle arrest	6	6
Chemosensitizer	6	6
Gastrointestinal Agents	3	6
Heme oxygenase-1 up-regulation	4	6
Anti-Fibrotic	3	4
Hypoglycemic Agents	2	4
Hypolipidemic	3	4
Cardioprotective	2	3
Acetylcholinesterase Inhibitor	1	2
Anti-Angiogenic	2	2
Anti-Asthmatic Agents	1	2
Autophagy Up-regulation	2	2
Bcl-2 protein down-regulation	1	2
Chemoprotective Agents	1	2
Postaglandin PGE2 downregulation	1	2
Renoprotective	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular Endothelial Growth Factor Inhibitors	1	2
Angiogenesis Inhibitors	1	1
Anti-Bacterial Agents	1	1
Cytoprotective	1	1
Immunomodulatory	1	1
Interleukin-5 downregulation	1	1
Multidrug Resistance Gene Modulators	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
interleukin-13 down-regulation	1	1

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Fucoidan and fucoxanthin attenuate hepatic steatosis and inflammation of NAFLD.Mar 11, 2021

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Pubmed Data : Mar Drugs. 2021 Feb 18 ;19(2). Epub 2021 Feb 18. PMID: 33670685

Article Published Date : Feb 17, 2021

Study Type : Animal Study, In Vitro Study

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Substances : Fucoxanthin

Diseases : Macular Degeneration

Pharmacological Actions : Antioxidants

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Fucoxanthin has therapeutic potential for improving asthma.May 24, 2021

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Pubmed Data : Nat Prod Res. 2018 Nov 29:1-5. Epub 2018 Nov 29. PMID: 30488724

Article Published Date : Nov 28, 2018

Study Type : Animal Study

Additional Links

Substances : Fucoxanthin

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor

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These results indicate the potential health-promoting effects of fucoxanthin in skin cancer prevention.Jan 19, 2018

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Pubmed Data : AAPS J. 2018 02 20 ;20(2):32. Epub 2018 Feb 20. PMID: 29603113

Article Published Date : Jan 19, 2018

Study Type : Animal Study

Additional Links

Substances : Astaxanthin, Fucoxanthin

Diseases : Skin Cancer

Pharmacological Actions : Antioxidants, Chemopreventive, Nrf2 activation

Additional Keywords : Epigenetic Modification In Cancer

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This study provides evidence of the protective effects of fucoxanthin supplementation against thyroid damage.Jul 20, 2020

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Pubmed Data : Biol Trace Elem Res. 2020 Jul 21. Epub 2020 Jul 21. PMID: 32691210

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Pubmed Data : Animals (Basel). 2021 May 23 ;11(6). Epub 2021 May 23. PMID: 34071074

Article Published Date : May 22, 2021

Study Type : In Vitro Study

Additional Links

Substances : Fucoxanthin

Diseases : Cancers: Canine

Pharmacological Actions : Angiogenesis Inhibitors, Apoptotic

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Fucoxanthin from microalgae Phaeodactylum tricornutum inhibits pro-inflammatory cytokines.Jan 11, 2021

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Pubmed Data : Sci Rep. 2021 Jan 12 ;11(1):543. Epub 2021 Jan 12. PMID: 33436909

Article Published Date : Jan 11, 2021

Study Type : In Vitro Study

Additional Links

Substances : Fucoxanthin

Diseases : Brain Inflammation , Neurodegenerative Diseases

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Pubmed Data : J Int Med Res. 2020 Oct ;48(10):300060520964011. PMID: 33086884

Article Published Date : Sep 30, 2020

Study Type : In Vitro Study

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Substances : Fucoxanthin

Diseases : Cervical Cancer

Pharmacological Actions : Antiproliferative

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Fucoxanthin prevents H2O2-induced neuronal apoptosis.Dec 31, 2016

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Pubmed Data : J Clin Biochem Nutr. 2017 Jul ;61(1):25-32. Epub 2017 May 16. PMID: 28751806

Article Published Date : Jun 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Fucoxanthin

Diseases : Colon Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : Cancer Stem Cells

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Green tea and caffeine have data to back up its fat metabolism-enhancing properties.Oct 01, 2011

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Pubmed Data : Obes Rev. 2011 Oct ;12(10):841-51. PMID: 21951331

Article Published Date : Oct 01, 2011

Study Type : Commentary

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Substances : B-complex, Caffeine, Carnitine, CLA (Conjugated Linoleic Acid), Fucoxanthin , Green Tea, Taurine, Tea

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Health benefits of fucoxanthin in the prevention of chronic diseases.Jan 09, 2020

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Pubmed Data : Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jan 10:158618. Epub 2020 Jan 10. PMID: 31931174

Article Published Date : Jan 09, 2020

Study Type : Review

Additional Links

Substances : Fucoxanthin

Diseases : Cancers: All, Chronic Disease, Diabetes Mellitus: Type 2, Liver Damage, Obesity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

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Pubmed Data : Prev Nutr Food Sci. 2019 Jun ;24(2):103-113. Epub 2019 Jun 30. PMID: 31328113

Article Published Date : May 31, 2019

Study Type : Review

Additional Links

Substances : Astaxanthin, B-Carotene, Crocetin, Cryptoxanthin, Fucoxanthin , Lutein, Lycopene

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hepatoprotective

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View the Evidence: 116 Abstracts with Fucoxanthin Research

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Fucoidan and fucoxanthin attenuate hepatic steatosis and inflammation of NAFLD.Mar 11, 2021

Fucoxanthin has potential for therapeutic efficacy in neurodegenerative disorders by acting on multiple targets.May 14, 2021

Fucoxanthin activates apoptosis and suppresses invasion and migration glioblastoma cells.Sep 30, 2016

Fucoxanthin exerted a protective effect against UV irradiation.Aug 31, 2016

Fucoxanthin reduced the inflammation response and maintained the integrity of the blood-retinal barrier.Nov 24, 2020

Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS-treated mice.Sep 16, 2020

Anti-inflammatory and apoptotic signalling effect of fucoxanthin on benzo(A)pyrene-induced lung cancer.Dec 31, 2018

Cytoprotective potential of fucoxanthin in oxidative stress-induced age-related macular degeneration.Feb 17, 2021

Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic mice.Aug 06, 2008

Dietary fucoxanthin induces anoikis in colorectal adenocarcinoma by suppressing integrin signalling in a murine colorectal cancer model.Dec 28, 2019

Effect of fucoxanthin on insulin resistance in obese mice induced by high fat diet.Dec 31, 2020

Effects of fucoxanthin on the iInhibition of dexamethasone-induced skeletal muscle loss in mice.Mar 25, 2021

Fucoidan and fucoxanthin in combination can potentially reduce cardiac hypertrophy, cardiac fibrosis, ROS level,Jan 20, 2019

Fucoxanthin could be a novel adjuvant for preventing exacerbations associated with skin inflammation as well as protecting skin against UV radiation.Oct 09, 2018

Fucoxanthin could be exploited as a therapeutic target for protecting neurons from cerebral ischemic/reperfusion injury.Sep 30, 2018

Fucoxanthin exhibits anti-obesity properties.Dec 01, 2009

Fucoxanthin had anti-inflammatory effects in a model of sepsis.Dec 31, 2018

Fucoxanthin has therapeutic potential for improving asthma.May 24, 2021

Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis.Jul 22, 2020

Fucoxanthin inhibits profibrotic protein expression in vitro and attenuates bleomycin-induced lung fibrosis in vivo.Sep 14, 2017

Fucoxanthin inhibits tumour-related lymphangiogenesis and growth of breast cancer.Jan 15, 2019

Fucoxanthin inhibits β-amyloid assembly and attenuates β-amyloid oligomer-induced cognitive impairments.May 23, 2017

fucoxanthin is a potential D3/D4 agonist for the management of neurodegenerative diseases.Jul 15, 2019

Fucoxanthin is a potential nutraceutical for preventing alcohol-induced liver injury.Sep 26, 2019

Fucoxanthin may have therapeutic potential as a treatment for patients with inflammatory diseases.Sep 28, 2015

Fucoxanthin may serve as a chemotherapeutic agent against liver cancer.Oct 30, 2018

Fucoxanthin might exhibit great therapeutic efficacy for the treatment of Alzheimer's disease.Mar 24, 2016

Fucoxanthin modulates cecal and fecal microbiota differently based on diet.Aug 31, 2019

Fucoxanthin possesses chemopreventive potential against progression of colorectal carcinogenesis in ApcMin/+ mice.Feb 28, 2021

Fucoxanthin potentiates anoikis in colon mucosa and prevents carcinogenesis in AOM/DSS model mice.Jan 31, 2019

Fucoxanthin prevents lipopolysaccharide-induced depressive-like behavior in mice.Dec 14, 2018

Fucoxanthin prevents pancreatic tumorigenesis in C57BL/6J mice.Dec 18, 2021

Fucoxanthin provides a limited reduction in alveolar bone resorption in rats with periodontitis.Mar 29, 2016

Fucoxanthin provides neuroprotection in models of traumatic brain injury.Apr 20, 2017

Fucoxanthin regulates Nrf2 signaling to decrease oxidative stress and improves renal fibrosis.Nov 11, 2021

fucoxanthin showed effective anti-asthma activity against ovalbumin-induced asthma.Dec 31, 2018

Fucoxanthin supplementation improves plasma and hepatic lipid metabolism and blood glucose concentration in high-fat fed mice.Apr 01, 2002

Fucoxanthin, lutein and tetrahydrocurcumin may have chemopreventive effects against colon carcinogenesis.Jan 01, 1998

Fucoxanthin-rich brown algae extract improves male reproductive function in a diabetes model.Sep 10, 2019

Fucoxanthin-rich fraction from Sargassum fusiformis alleviates particulate matter-induced inflammation.Dec 31, 2020

Fucoxanthin-rich seaweed extract suppresses body weight gain and improves lipid metabolism in high-fat-fed mice.Sep 01, 2010

Low-molecular-weight fucoidan and fucoxanthin supplementation exerts a beneficial effect on hepatic glucose levels and glucose homeostasis.Apr 06, 2017

Modulation of gut microbiota by fucoxanthin during alleviation of obesity in high-fat diet-fed mice.Apr 27, 2020

Neuroprotective effect of fucoxanthin against Intracerebroventricular streptozotocin (ICV-STZ) induced cognitive impairment.Dec 31, 2020

Oligo-fucoidan, fucoxanthin, and L-carnitine have a combined protective effect on the kidneys.Nov 01, 2020

Oral supplementation of fucoxanthin-rich brown algae extract ameliorates cisplatin-induced testicular damage.Apr 30, 2020

Pretreatment with fucoxanthin may protect against UVB radiation-induced corneal disorders.Jan 06, 2016

Protective effects of fucoxanthin on hydrogen peroxide-induced calcification of heart valve interstitial cells.May 25, 2021

Role of fucoxanthin towards cadmium-induced renal impairment with the antioxidant and anti-lipid peroxide activities.Nov 30, 2021

Suppression of C-C chemokine receptor 1 is a key regulation for colon cancer chemoprevention.Sep 23, 2021

The in vivo experiment also confirmed the superiority of fucoxanthin than lutein in protecting retina against photoinduced damage. Jan 19, 2016

These finding suggested that the use of fucoxanthin provides a new and attractive alternative to control ulcerative colitis.Nov 28, 2018

These results indicate the potential health-promoting effects of fucoxanthin in skin cancer prevention.Jan 19, 2018

This study provides evidence of the protective effects of fucoxanthin supplementation against thyroid damage.Jul 20, 2020

A review of dietary carotenoids in cancer chemoprevention and chemotherapy.Jun 30, 2020

Anti-apoptotic effects of carotenoids in neurodegeneration. Jul 28, 2020

Anti-inflammatory and anticancer effects of microalgal carotenoids. Sep 22, 2021

Anticancer effects of seaweed compound fucoxanthin alone and in combination with 5-fluorouracil in colon cells.Aug 28, 2017

Bixin and fucoxanthin sensitize human lung cancer and cervical cancer cell to cisplatin in vitro.Dec 17, 2021

Effects of fucoxanthin on autophagy and apoptosis in SGC-7901cells and the mechanism.Aug 31, 2018

Fucoxanthin alleviates palmitate-induced inflammation in RAW 264.7 cells through improving lipid metabolism and attenuating mitochondrial dysfunction. Apr 29, 2020

Fucoxanthin ameliorates atopic dermatitis symptoms by regulating keratinocytes and regulatory innate lymphoid cells.Mar 21, 2020

Fucoxanthin and colorectal cancer prevention. May 13, 2021

Fucoxanthin and neoxanthin induce apoptosis in human prostate cancer cells.Dec 01, 2001

Fucoxanthin and TRAIL increased the apoptosis in human cervical cancer cells.Dec 31, 2017

Fucoxanthin attenuates fatty acid-induced lipid accumulation in FL83B hepatocytes.Dec 31, 2017

Fucoxanthin attenuates LPS-induced acute lung injury.Dec 10, 2020

Fucoxanthin combined with other drugs could enhance the effect of both fucoxanthin and the other drug or reduce the dose without reducing the effect.Jan 08, 2019

Fucoxanthin could be a promising compound for cancer therapy by acting on most of the classical hallmarks of tumor cells.Dec 03, 2020

Fucoxanthin demonstrates anti-angiogenic activity. Dec 01, 2001

Fucoxanthin exerts anti-fibrogenic effects in hepatic stellate cells.Apr 10, 2019

Fucoxanthin exerts anti-tumor activity on canine mammary tumor cells.May 22, 2021

Fucoxanthin

View the Evidence:
116 Abstracts with Fucoxanthin Research