Genipin

Views 44
Jump to
Abstracts Focused Research Topics
Your Token Count0

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
1 Diseases Researched for Genipin
NameACCKFocus
Breast Cancer11Locked
1 Pharmacological Actions Researched for Genipin
NameACCKFocus
Chemopreventive11Locked

View the Evidence:
37 Abstracts with Genipin Research

[+]

Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation.Jan 31, 2018

Pubmed Data : FEBS J. 2018 Feb ;285(3):501-517. Epub 2017 Dec 26. PMID: 29197188
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Hyperlipidemia
Pharmacological Actions : Hepatoprotective, Hypolipidemic, MicroRNA modulator
[+]

Genipin ameliorates diet-induced obesity via promoting lipid mobilization and browning of white adipose tissue.Jan 28, 2018

Pubmed Data : Phytother Res. 2018 Jan 29. Epub 2018 Jan 29. PMID: 29377296
Article Published Date : Jan 28, 2018
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Obesity Agents
[+]

Genipin ameliorates hypertension-induced renal damage.Jun 30, 2016

Pubmed Data : Fitoterapia. 2016 Jul ;112:244-53. Epub 2016 Jun 23. PMID: 27343367
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Hypertension, Kidney Damage
Pharmacological Actions : Antihypertensive Agents, Renoprotective
[+]

Genipin enhances the therapeutic effects of oxaliplatin by upregulating BIM in colorectal cancer.Feb 19, 2019

Pubmed Data : Mol Cancer Ther. 2019 Feb 20. Epub 2019 Feb 20. PMID: 30787174
Article Published Date : Feb 19, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genipin
Diseases : Colorectal Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Oxaliplatin
[+]

Genipin has significant gastroprotective effects and might be useful for treating and preventing gastric lesions.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2017 ;40(2):151-154. PMID: 28154253
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Gastric Ulcer, Gastrointestinal Diseases
Pharmacological Actions : Gastroprotective
[+]

Genipin inhibited LPS-induced inflammatory response by activating Nrf2 signalling pathway in BV2 microglia.Sep 30, 2017

Pubmed Data : Neurochem Res. 2017 Oct ;42(10):2769-2776. Epub 2017 May 11. PMID: 28497344
Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genipin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Nrf2 activation, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Genipin inhibits allergic responses in ovalbumin-induced asthmatic mice.Nov 30, 2017

Pubmed Data : Int Immunopharmacol. 2017 Dec ;53:49-55. Epub 2017 Oct 15. PMID: 29035815
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents, Cyclooxygenase 2 Inhibitors, interleukin-13 down-regulation, Interleukin-5 downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Genipin inhibits the growth of human bladder cancer cells.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Feb ;15(2):2619-2624. Epub 2017 Dec 11. PMID: 29434982
Article Published Date : Jan 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genipin
Diseases : Bladder Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Genipin may be a promising preventative treatment to slow the degradation of cartilage.Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Orthop Res. 2015 Nov ;33(11):1571-1579. Epub 2015 May 18. PMID: 25939430
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Cartilage Diseases
Pharmacological Actions : Osteoprotective
Additional Keywords : Plant Extracts
[+]

Genipin may provide a novel therapeutic option for preventing and treating infants with bronchopulmonary dysplasia.Dec 31, 2018

Pubmed Data : Nutrition. 2019 Jan ;57:237-244. Epub 2018 Jun 19. PMID: 30196116
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Bronchopulmonary Dysplasia, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Genipin may represent a promising immunomodulatory therapeutic candidate for hepatocellular carcinoma.Jul 11, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Jul 12 ;7(28):43792-43804. PMID: 27270308
Article Published Date : Jul 11, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genipin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Immunomodulatory
[+]

Genipin might be a potential therapeutic agent for the treatment of sepsis.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2016 Mar ;173(6):980-91. Epub 2016 Feb 10. PMID: 26660048
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Liver Damage, Sepsis
Pharmacological Actions : Hepatoprotective, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Genipin modulates monoaminergic transmission and levels of brain-derived neurotrophic factor in rat model of depression.Sep 04, 2014

Pubmed Data : Neuroscience. 2014 Sep 5 ;275:365-73. Epub 2014 Jun 24. PMID: 24972301
Article Published Date : Sep 04, 2014
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
Additional Keywords : Phytotherapy
[+]

Genipin normalizes depression-like behavior induced by prenatal stress through inhibiting DNMT1.Mar 08, 2018

Pubmed Data : Epigenetics. 2018 Mar 9:1-22. Epub 2018 Mar 9. PMID: 29522357
Article Published Date : Mar 08, 2018
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Depression
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
[+]

Genipin protects against cerebral ischemia-reperfusion injury.Feb 14, 2019

Pubmed Data : Eur J Pharmacol. 2019 Feb 15 ;845:56-64. Epub 2018 Dec 21. PMID: 30582911
Article Published Date : Feb 14, 2019
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Genipin protects the liver from ischemia-reperfusion injury by modulating mitochondrial quality control.Dec 31, 2016

Pubmed Data : Toxicol Appl Pharmacol. 2017 08 1 ;328:25-33. Epub 2017 May 3. PMID: 28477916
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Lipid Peroxidation, Liver Injury: Ischemia/reperfusion , Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Genipin Reverses high fat diet-induced liver damage.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2018 ;49(5):1885-1897. Epub 2018 Sep 20. PMID: 30235442
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genipin
Diseases : High Fat Diet, Liver Damage, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Hepatoprotective
[+]

Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway.Nov 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Nov 24 ;8(60):101952-101964. Epub 2017 Oct 16. PMID: 29254217
Article Published Date : Nov 23, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genipin
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Geniposide and genipin have a healthy promotion to eradicate H. pylori infections.Nov 30, 2017

Pubmed Data : J Food Sci. 2017 Dec ;82(12):3021-3028. Epub 2017 Nov 14. PMID: 29135040
Article Published Date : Nov 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genipin
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Bacterial Agents, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interferon Gamma Reducer, Interleukin-1 beta downregulation
[+]

These findings suggest that genipin protects against apoptosis and inflammation in lipopolysaccharide-induced acute lung injury by promoting autophagy.Apr 04, 2019

Pubmed Data : Int Immunopharmacol. 2019 Apr 5 ;72:21-30. Epub 2019 Apr 5. PMID: 30959368
Article Published Date : Apr 04, 2019
Study Type : Animal Study
Additional Links
Substances : Genipin
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A review of the therapeutic potential of genipin in central neurodegenerative diseases.Sep 30, 2016

Pubmed Data : CNS Drugs. 2016 Oct ;30(10):889-97. PMID: 27395402
Article Published Date : Sep 30, 2016
Study Type : Review
Additional Links
Substances : Genipin
Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Neuroprotective Agents
[+]

Fluoxetine increased the migratory distance of liver cancer cells, but is counteracted by ginipin. Dec 13, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Dec 14 ;23(12). Epub 2018 Dec 14. PMID: 30558243
Article Published Date : Dec 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Cancer Metastasis, Liver Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords : Increased Risk, Risk Reduction
Problem Substances : Fluoxetine (trade name Prozac)
[+]

Genipin alleviates LPS-induced acute lung injury by inhibiting NF-κB and NLRP3 signaling pathways.Aug 31, 2016

Pubmed Data : Int Immunopharmacol. 2016 Sep ;38:115-9. Epub 2016 Jun 2. PMID: 27262946
Article Published Date : Aug 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor
[+]

Genipin attenuates cisplatin-induced nephrotoxicity.Aug 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Sep ;93:1083-1097. Epub 2017 Jul 20. PMID: 28738532
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Genipin attenuates LPS-induced changes of emotional behaviours through inhibition of neural activation and inflammatory responses.Oct 14, 2014

Pubmed Data : Eur J Pharmacol. 2014 Oct 15 ;741:1-7. Epub 2014 Jul 30. PMID: 25084220
Article Published Date : Oct 14, 2014
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Genipin could be used for the treatment of periodontal disease to prevent MMPs expression in periodontal lesion.Nov 30, 2014

Pubmed Data : Biochimie. 2014 Dec ;107 Pt B:391-5. PMID: 25457105
Article Published Date : Nov 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Periodontal Diseases
Pharmacological Actions : Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Genipin induces cell death via intrinsic apoptosis pathways in human glioblastoma cells.Aug 29, 2018

Pubmed Data : J Cell Biochem. 2018 Aug 30. Epub 2018 Aug 30. PMID: 30160798
Article Published Date : Aug 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Glioblastoma
Pharmacological Actions : Apoptotic
[+]

Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.Dec 10, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 Dec 11 ;5:17935. Epub 2015 Dec 11. PMID: 26659006
Article Published Date : Dec 10, 2015
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation
[+]

Genipin may be used as a novel therapeutic agent in the treatment of colon cancer .Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Sep ;16(3):2957-2964. Epub 2018 Jun 26. PMID: 30127884
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation
[+]

Genipin protects against H2O2-induced oxidative damage in retinal pigment epithelial cells by promoting Nrf2 signaling.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2019 Feb ;43(2):936-944. Epub 2018 Dec 12. PMID: 30569096
Article Published Date : Jan 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Hydrogen Peroxide Induced Toxicity, Macular Degeneration
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Genipin protects d-galactosamine and lipopolysaccharide-induced hepatic injury.Oct 04, 2017

Pubmed Data : Eur J Pharmacol. 2017 Oct 5 ;812:128-137. Epub 2017 Jul 11. PMID: 28709622
Article Published Date : Oct 04, 2017
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
[+]

Genipin suppresses NLRP3 inflammasome activation through uncoupling protein-2.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Immunol. 2015 Sep ;297(1):40-5. Epub 2015 Jun 16. PMID: 26123077
Article Published Date : Aug 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Potential role of genipin in cancer therapy.Dec 31, 2017

Pubmed Data : Pharmacol Res. 2018 07 ;133:195-200. Epub 2018 May 24. PMID: 29758279
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Genipin
Diseases : Cancers: All
Pharmacological Actions : Antineoplastic Agents, Apoptotic, Chemotherapeutic
[+]

Shorter the Genipin treatment before Cisplatin better promoted the cisplatin induced ROS and subsequent cell death.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2016 ;13(7):507-16. Epub 2016 Jun 29. PMID: 27429587
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

The present review may provide information on the use of these natural compounds for the prevention of breast cancer.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer Prev. 2015 Dec ;20(4):223-31. Epub 2015 Dec 30. PMID: 26734584
Article Published Date : Nov 30, 2015
Study Type : Review
Additional Links
Substances : Capsaicin, Curcumin, Genipin, Lycopene, Ursolic Acid
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
[+]

These results provide new insights into the potential role of genipin in suppressing colon cancer progression.May 31, 2018

Pubmed Data : Food Chem Toxicol. 2018 Jun ;116(Pt B):70-76. Epub 2018 Apr 6. PMID: 29630948
Article Published Date : May 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Cancer Metastasis, Colon Cancer, Hypoxia
Pharmacological Actions : Anti-metastatic, Vascular Endothelial Growth Factor A Inhibitor
[+]

This describes the chemopreventive properties of genipin on AGS cell line.Dec 31, 2015

Pubmed Data : J Biochem Mol Toxicol. 2016 Jan ;30(1):45-54. Epub 2015 Sep 17. PMID: 26377927
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Genipin
Diseases : Gastric Cancer, Oxidative Stress
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

Copyright: northpic / 123RF Stock Photo

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2019 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.