Ginseng

Name	AC	CK
Oxidative Stress	42	119
Diabetes Mellitus: Type 2	17	70
Hypertension	8	60
Lung Cancer	31	51
Liver Cancer	30	50
Alzheimer's Disease	31	47
HIV Infections	7	45
Inflammation	30	45
DNA damage	7	44
Cancers: All	17	41
Lipopolysaccharide-Induced Toxicity	28	40
Breast Cancer	26	38
Obesity	19	37
Colorectal Cancer	16	35
Depression	17	35
Aging Skin	4	32
Influenza A	7	30
Cerebral Ischemia	16	28
Chemotherapy-Induced Toxicity: Cisplatin	14	28
Fatigue	7	28
Myocardial Ischemia	11	28
Stroke: Ischemic	6	27
Radiation Induced Illness	5	26
Brain Ischemia	9	25
Colon Cancer	14	24
Memory Disorders	11	24
Chemically-Induced Liver Damage	12	23
Nonalcoholic fatty liver disease (NAFLD)	7	21
Acetaminophen (Tylenol) Toxicity	9	20
Common Cold	2	20
Dry Eye Syndromes	1	20
Low Immune Function: Natural Killer Cells	2	20
Upper Respiratory Infections	2	20
Cancers: Drug Resistant	9	19
Cognitive Decline/Dysfunction	10	19
Atopic Dermatitis	4	18
Diabetic Complications	9	18
Lipid Peroxidation	5	18
Heart Failure	5	17
Erectile Dysfunction	5	16
Leukemia: Acute myelogenous leukemia (AML)	5	15
Melanoma	11	15
Neurodegenerative Diseases	11	15
Ovarian Cancer	12	15
Stroke	4	15
Aging: Brain	6	14
Cardiovascular Diseases	7	14
Diabetes Mellitus: Type 1	8	14
Hair Loss	4	14
High Fat Diet	6	14
Hypoxia	10	14
Parkinson's Disease	9	14
Spinal Cord Injuries	8	14
Cancer Metastasis	12	13
Carcinoma: Non-Small-Cell Lung	3	13
Colitis	7	13
Respiratory Syncytial Virus Infections	3	13
Athletic Performance	2	12
Attention Deficit Disorder with Hyperactivity	2	12
Chronic Obstructive Pulmonary Disease	2	12
Congestive Heart Failure	2	12
Brain Inflammation	7	11
Cholesterol: Oxidation	2	11
Halitosis	2	11
Hepatitis B	2	11
Huntington Disease	3	11
Respiratory Diseases	2	11
Sepsis	7	11
Sperm Quality: Low	2	11
Wound Healing	6	11
Acne	1	10
Acquired Immunodeficiency Syndrome	1	10
Acute Respiratory Distress Syndrome	1	10
Arterial Hardening: Elasticity	1	10
Asthenozoospermia	1	10
Bisphenol-A Toxicity	1	10
Cancer: Fatigue	1	10
Chemotherapy-Induced Toxicity: Oxaliplatin	1	10
Chronic Fatigue Syndrome	1	10
Chronic Kidney Disease (CKD)	1	10
Cold and Flu	1	10
Cold: Common	1	10
Flu	1	10
Helicobacter Pylori Infection	1	10
Human Flu	1	10
Human Influenza	1	10
Hypothyroidism	1	10
Immune Disorders: Low Immune Function	1	10
Infertility: Male	1	10
Lower Respiratory Infections	1	10
Osteoarthritis	4	10
Postmenopausal Disorders	1	10
Schizophrenia	1	10
Tinnitus	1	10
Insulin Resistance	6	9
Myocardial Infarction	5	9
Aging	3	8
Alcohol Toxicity	4	8
Cardiac Hypertrophy	4	8
Cervical Cancer	6	8
Chemotherapy-Induced Toxicity: Doxorubicin	5	8
Endometriosis	4	8
Esophageal Cancer	5	8
Fatigue: Excercise-Induced	3	8
Glioblastoma	5	8
Hyperglycemia	3	8
Ischemia	5	8
Leukemia	7	8
Multiple Sclerosis	5	8
Prostate Cancer	7	8
Atherosclerosis	4	7
Chemotherapy and Radiation Toxicity	2	7
Chemotherapy-Induced Toxicity: Cyclophosphamide	4	7
Glioma	6	7
H1N1 Infection	3	7
Hydrogen Peroxide Induced Toxicity	6	7
Lung Injury: Acute	4	7
Skin Cancer	6	7
Ultraviolet Radiation Induced Damage	6	7
Alopecia	2	6
Autoimmune Diseases	2	6
Breast Cancer: Triple Negative	5	6
Dementia	4	6
Diabetic Nephropathy	3	6
Hyperlipidemia	2	6
Itching	2	6
Liver Fibrosis	3	6
Pancreatic Cancer	4	6
Promyelocytic leukemia	5	6
Rheumatoid Arthritis	3	6
Squamous cell carcinoma	5	6
Brain: Microglial Activation	4	5
Gastric Cancer	4	5
Learning disorders	3	5
Lung Injury: Smoke-Induced	3	5
Scars	3	5
Stroke: Attenuation/Recovery	3	5
Air Pollution Linked Toxicity	1	4
Anxiety	2	4
Burns	2	4
Chemotherapy-Induced Toxicity: 5-fluorouracil	1	4
Dermatitis	2	4
Diabetes: Cognitive Dysfunction	2	4
Diabetic Retinopathy	2	4
Encephalomyelitis	1	4
Endometrial Cancer	3	4
Fatigue: Cancer-Associated	1	4
Hearing Loss: Noise-Induced	1	4
Hepatic Steatosis	2	4
Hypertension: Pulmonary	2	4
Intestinal Ischemia	2	4
Kidney Failure: Acute	2	4
Liver Damage	3	4
Liver Disease	3	4
Low Libido	2	4
Metabolic Syndrome X	2	4
Mitochondrial Dysfunction	3	4
Morphine Tolerance/Dependence	1	4
Osteoporosis	3	4
Polycystic Ovary Syndrome	2	4
Pseudomonas aeruginosa	2	4
Radiation-Induced Illness: Cesium-137 Exposure	3	4
Sleep Disorders	2	4
Staphylococcus aureus infection	2	4
Acute Myeloid Leukemia	3	3
Amyotrophic lateral sclerosis (ALS)	2	3
Breast Cancer: Metastatic	1	3
Central Nervous System Diseases	2	3
Coxsackievirus Infections	3	3
Dyslipidemias	2	3
Gallbladder Cancer	2	3
Inflammatory Bowel Diseases	2	3
Liver Cirrhosis	2	3
Multiple Myeloma	3	3
Osteosarcoma	3	3
Tertiary butyl hydroperoxide toxicity	2	3
Thyroid Cancer	2	3
Vaginal Cancer	2	3
Adiponectin: Low Levels	1	2
Advanced Glycation End products (AGE)	1	2
Alcoholic Liver Disease	1	2
Anemia	1	2
Aneurysm: Aortic	1	2
Arthritis	1	2
Arthritis: Rheumatoid	1	2
Bisphenol Toxicity	1	2
Bladder Cancer	2	2
Brain Cancer	2	2
Brain: Oxidative Stress	1	2
Cachexia	1	2
Cardiomegaly	1	2
Cardiomyopathy	1	2
Cerebral Aneurysm	1	2
Chemobrain	1	2
Chemotherapy-Induced Neurotoxicity	1	2
Chemotherapy-Induced Toxicity: Adriamycin	1	2
Chemotherapy-Induced Toxicity: Bleomycin	1	2
Colitis: Pseudomembranous	1	2
Colon Cancer: Prevention	1	2
Colon Polyps	1	2
Depression	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Kidney Function	1	2
Diabetes: Oxidative Stress	1	2
Drug Toxicity: Cephaloridine	1	2
Drug-Induced Toxicity: Cyclosporine	1	2
Dysmenorrhea	1	2
Encephalopathy	1	2
Exercise-Induced Tissue Damage	1	2
Fatty Liver	1	2
Fluoride Toxicity	1	2
Gastric Ulcer	1	2
Gastritis	1	2
Gastrointestinal polyps	1	2
H5N1 Infection	1	2
Hashimoto's thyroiditis	1	2
Hepatitis A	2	2
Hepatitis C	2	2
Herbicide Toxicity	1	2
Herpes family viruses	1	2
Hypercapnia	1	2
Hypercholesterolemia	1	2
Hyperhomocysteinemia	2	2
Hypoglycemia	1	2
Inappropriate Luteinizing Hormone Secretion	1	2
Infertility: Female	1	2
Intoxication	1	2
Ischemia: Myocardial	1	2
Keloid	1	2
Kidney Fibrosis	1	2
Leukemia: Chronic myelogenous leukemia (CML)	2	2
Liver Failure: Acute	1	2
Liver Steatosis	1	2
Low Testosterone	1	2
Lymphoma	1	2
Mastitis	1	2
Melanoma: Metastasis	1	2
Memory Disorders: Drug-Induced	1	2
Metabolic Diseases	1	2
Middle Cerebral Artery Occlusion (MCAO)	1	2
Mitochondrial Diseases	2	2
Muscle Atrophy	2	2
Myocardial Fibrosis	1	2
Nerve Injuries	1	2
Neuroblastoma	2	2
Obstructive Nephropathy	1	2
Ovarian Failure	1	2
Pain	1	2
Pancreatic Diseases	1	2
Pneumonia	1	2
Postoperative Recovery	1	2
Prostatic Hyperplasia: Benign	1	2
Prostatitis: Bacterial	1	2
Psoriasis	1	2
Radiation-Induced Illness: Radioiodine (Iodine-131)	1	2
Rhinovirus Infection	2	2
Right Ventricular Hypertrophy	1	2
Rotavirus Infections	1	2
Sarcopenia	1	2
Sciatica	1	2
Skin Diseases: Photo-Aging	1	2
Smoking: Pulmonary	1	2
Streptococcus pneumoniae infection	1	2
Subarachnoid hemorrhage	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Testosterone: Too Low	1	2
Toxoplasma gondii Infection	1	2
Toxoplasmosis	1	2
Triglycerides: Elevated	1	2
Ulcerative Colitis	1	2
Acute T cell Leukemias	1	1
Acute lymphoblastic leukemia (ALL)	1	1
Aluminum Toxicity	1	1
Asthma	1	1
Benzo[a]pyrene-induced Toxicity	1	1
Bone Diseases	1	1
Brain Hypoxia	1	1
Brain Injury: Hippocampal Damage	1	1
Brain Injury: Traumatic	1	1
C-Reactive Protein	1	1
Cancers: Multi-Drug Resistant	1	1
Candidiasis	1	1
Cocaine Withdrawal	1	1
Degenerative Disk Disease	1	1
Demyelinating Diseases	1	1
Dental Caries	1	1
Endothelial Damage	1	1
Enterovirus	1	1
Enterovirus: Type 71	1	1
Fibrosarcoma	1	1
Fibrosis	1	1
Gastrointestinal Cancer	1	1
Glioblastoma Multiforme	1	1
Glioma: Astrocytic	1	1
H3N2 Infection	1	1
HIV Protease Inhibitor Ritonavir Toxicity	1	1
Hangover	1	1
Herpes Simplex Virus Type 1	1	1
Histamine: Elevated	1	1
Homocysteine: Elevated	1	1
Immune Dysregulation: TH1 dominance	1	1
Immune Dysregulation: TH1/TH2 imbalance	1	1
Kidney Cancer	1	1
Lead Poisoning	1	1
Leukemia: Multi-Drug Resistant	1	1
Medulloblastoma	1	1
Nasopharyngeal Cancer	1	1
Norovirus	1	1
Organ Transplantation	1	1
Pesticide Toxicity	1	1
Porphyromonas gingivalis	1	1
Prion Diseases	1	1
Progesterone: Low	1	1
Retinal Diseases	1	1
Retinoblastoma	1	1
Scars: Hyperplastic	1	1
Stem Cell Transplant	1	1
Steptococcus Mutans Infections	1	1
Surgery: Anesthesiology	1	1
Wrinkles	1	1
Cortisone Toxicity	1	0

Name	AC	CK
Anti-Inflammatory Agents	119	260
Antioxidants	102	252
Neuroprotective Agents	125	235
Antiproliferative	106	156
Apoptotic	109	140
Tumor Necrosis Factor (TNF) Alpha Inhibitor	61	107
Anti-Apoptotic	58	98
Hepatoprotective	41	87
Cardioprotective	40	77
Hypoglycemic Agents	21	75
Interleukin-6 Downregulation	35	71
NF-kappaB Inhibitor	40	66
Interleukin-1 beta downregulation	36	65
Immunomodulatory	24	61
Anti-metastatic	37	57
Chemoprotective Agents	23	56
Chemotherapeutic	28	52
Cyclooxygenase 2 Inhibitors	31	48
Chemopreventive	13	46
Matrix metalloproteinase-2 (MMP-2) inhibitor	20	45
Malondialdehyde Down-regulation	19	43
Antihypertensive Agents	5	38
Hypolipidemic	13	36
Antiviral Agents	11	35
Chemosensitizer	19	35
Antidepressive Agents	16	33
Antineoplastic Agents	27	33
Superoxide Dismutase Up-regulation	13	33
Vascular Endothelial Growth Factor Inhibitors	17	32
Matrix metalloproteinase-9 (MMP-9) inhibitor	14	31
Radioprotective	7	30
Cell cycle arrest	22	29
Nrf2 activation	18	27
Renoprotective	11	27
Antimicrobial	5	24
Anti-Fibrotic	8	22
Anti-Angiogenic	9	21
Anti-HIV Agents	2	21
HIV Protease Inhibitors	1	20
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	9	20
MicroRNA modulator	11	18
Bcl-2 protein down-regulation	14	17
Immunostimulatory	6	17
Brain-derived neurotrophic factor modulator	8	15
Angiogenesis Inhibitors	10	14
Autophagy Up-regulation	9	13
Nitric Oxide Inhibitor	8	12
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	11
Tumor Suppressor Protein p53 Upregulation	8	11
Cytoprotective	7	10
Genoprotective	1	10
Tumor Necrosis Factor (TNF) Alpha Enhancer	1	10
Angiogenesis Inducing Agents	4	8
Anticarcinogenic Agents	4	7
Chondroprotective	2	7
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	3	7
Pancreato Protective Agents	4	7
Photoprotective	6	7
Antipruritics	2	6
Immunomodulatory: Th17 downregulation	2	6
Neuritogenic	4	6
Osteoprotective	4	6
Autophagy Inhibitors	4	5
Heme oxygenase-1 up-regulation	3	5
Histone deacetylase inhibitor	3	5
Interferon Gamma Reducer	3	5
Prophylactic Agents	3	5
Prostaglandin PGE2 downregulation	1	5
Secretagogue	3	5
Wnt/β-catenin signaling pathway modulation	4	5
Anti-Adipogenic	2	4
Anti-Platelet	1	4
Anti-atherogenic	2	4
Anticholesteremic Agents	2	4
Antinoceceptive	2	4
Aphrodisiac	2	4
Enzyme Inhibitors	3	4
Gastroprotective	2	4
Radiosensitizer	3	4
Vascular Endothelial Growth Factor A Inhibitor	2	4
Vasodilator Agents	2	4
Viral Hemagglutinin Inhibitor	1	4
Heat Shock Protein Down-Regulation	2	3
Interleukin-4 downregulation	2	3
SIRT1 Activator	2	3
Telomerase Inhibitor	2	3
Transforming growth factor beta (TGF-β) inhibitor	2	3
Acetylcholinesterase Inhibitor	1	2
Adiponectin upregulation	1	2
Alpha-amylase inhibitor	1	2
Analgesics	1	2
Analgesics: Non-Narcotic	1	2
Anti-Anxiety Agents	1	2
Anti-Bacterial Agents	1	2
Antimutagenic Agents	1	2
Caspase-3 Activation	1	2
Caspase-8 activation	1	2
Catalase Up-Regulation	1	2
DNA Repair Up-regulation	2	2
E-cadherin down-regulation	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Fertility Agents: Female	1	2
Gastrointestinal Agents	1	2
Glucose transporter-2 (GLUT2) expression down-regulation	1	2
Heme oxygenase-1 inducer	2	2
Histamine Agents	1	2
Immunomodulatory: Regulatory T Cell Up-Regulation	1	2
Immunosuppressive Agents	1	2
Interleukin-10 downregulation	1	2
Interleukin-10 upregulation	1	2
Interleukin-17 downregulation	1	2
Interleukin-18 down-regulation	1	2
Interleukin-2 upregulation	1	2
Interleukin-8 downregulation	2	2
Multidrug Resistance Gene Modulators	1	2
Neurogenesis	1	2
Neurorestorative	1	2
Nitric Oxide Enhancer	1	2
P21 Activation	1	2
Regenerative	1	2
Vascular Endothelial Growth Factor C Inhibitor	1	2
Vascular Endothelial Growth Factor Regulator	2	2
Acetylcholinesterase Down-Regulation	1	1
Anti-Retroviral Agents	1	1
Antifungal Agents	1	1
Cholinesterase Inhibitors	1	1
Cyclin D1 Down-Regulation	1	1
Dopaminergic	1	1
Fertility Agents: Male	1	1
Glucagon Like peptide 1 (GLP-1) Up-regulation	1	1
Hematologic Agents	1	1
Histamine down-regulation	1	1
Insulin Sensitizers	1	1
Insulin-Like Growth Factor Enhancer/Upregulation	1	1
Insulin-releasing	1	1
Interleukin-1 alpha downregulation	1	1
Interleukin-12 downregulation	1	1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	1	1
Paraptosis	1	1
Survivin Down-Regulation	1	1
Vascular Endothelial Growth Factor A Enhancer	1	1

Pubmed Data : Nutr Neurosci. 2019 Nov 18:1-12. Epub 2019 Nov 18. PMID: 31736428

Article Published Date : Nov 17, 2019

American Ginseng is safe and effective in reducing relative risk and duration of respiratory symptoms associated with "cold and flu" in adults. Mar 01, 2006

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Pubmed Data : J Altern Complement Med. 2006 Mar;12(2):153-7. PMID: 16566675

Article Published Date : Mar 01, 2006

Study Type : Human Study

Additional Links

Substances : Ginseng (American)

Diseases : Cold: Common, Common Cold, Human Flu, Human Influenza, Influenza A

Pharmacological Actions : Antiviral Agents

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American ginseng is safe, well tolerated, and potentially effective for preventing acute respiratory illness due to influenza and respiractory syncytial virus infections.Jan 01, 2004

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Pubmed Data : J Am Geriatr Soc. 2004 Jan;52(1):13-9. PMID: 14687309

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Pubmed Data : J Transl Med. 2014 ;12:283. Epub 2014 Oct 9. PMID: 25297058

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Low Immune Function: Natural Killer Cells

Pharmacological Actions : Immunomodulatory, Immunostimulatory, Tumor Necrosis Factor (TNF) Alpha Enhancer

Additional Keywords : Significant Treatment Outcome

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Ginseng could improve glucose control and insulin sensitivity in patients with T2DM or impaired glucose intolerance.Jan 31, 2016

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Pubmed Data : Medicine (Baltimore). 2016 Feb ;95(6):e2584. PMID: 26871778

Article Published Date : Jan 31, 2016

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Pubmed Data : J Ginseng Res. 2021 Jan ;45(1):191-198. Epub 2020 Sep 16. PMID: 33437171

Article Published Date : Dec 31, 2020

Study Type : Human Study

Additional Links

Substances : Ginseng (Korean)

Pharmacological Actions : Immunostimulatory

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In this preliminary study korean red ginseng significantly lowered the incidences of acute respiratory infections. Nov 30, 2012

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Pubmed Data : J Korean Med Sci. 2012 Dec ;27(12):1472-8. Epub 2012 Dec 7. PMID: 23255845

Article Published Date : Nov 30, 2012

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Pubmed Data : Eur J Cancer. 2020 May ;130:51-62. Epub 2020 Mar 13. PMID: 32172198

Article Published Date : Apr 30, 2020

Study Type : Human Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Cancer: Fatigue, Colorectal Cancer

Pharmacological Actions : Chemotherapeutic

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Korean red ginseng lowers urinary BPA levels and BPA-induced malondialdehyde levels and alleviates gynecological complaints without side effects of raw-ginseng.Dec 31, 2013

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Pubmed Data : BMC Complement Altern Med. 2014 ;14:265. Epub 2014 Jul 25. PMID: 25063041

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Bisphenol-A Toxicity, Oxidative Stress

Pharmacological Actions : Chemopreventive, Malondialdehyde Down-regulation

Additional Keywords : Detoxification, Plant Extracts

Problem Substances : Bisphenol A

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Pharmacological Actions : Matrix metalloproteinase-2 (MMP-2) inhibitor

Additional Keywords : Plant Extracts

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The combination of transcatheter arterial chemoembolization and ginsenoside Rg3 may prolong overall survival when compared with it alone.Jul 31, 2016

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Pubmed Data : J Ethnopharmacol. 2020 Aug 24:113271. Epub 2020 Aug 24. PMID: 32853742

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Pubmed Data : Nanomedicine (Lond). 2020 Jan ;15(1):41-54. PMID: 31868113

Article Published Date : Dec 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Betulinic acid, Ginsenosides, Honokiol, Parthenolide

Diseases : Lung Cancer

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Natural Substance Synergy

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A combination of Korean red ginseng extract and Glycyrrhiza glabra L. extract enhances their individual anti-obesity properties.Feb 29, 2020

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Pubmed Data : Int J Mol Med. 2018 Mar ;41(3):1487-1499. Epub 2018 Jan 4. PMID: 29328420

Article Published Date : Feb 28, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginsenosides

Diseases : Keloid

Pharmacological Actions : Antiproliferative , Transforming growth factor beta (TGF-β) inhibitor

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Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed mice.Jun 30, 2018

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Pubmed Data : J Ginseng Res. 2018 Jul ;42(3):352-355. Epub 2017 Apr 24. PMID: 29983617

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Pubmed Data : J Ginseng Res. 2016 Jul ;40(3):237-44. Epub 2015 Aug 12. PMID: 27616899

Article Published Date : Jun 30, 2016

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

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An extract of black ginseng ameliorated hypercholesterolemia in rats fed a high-cholesterol diet.Mar 31, 2016

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Pubmed Data : J Ginseng Res. 2016 Apr ;40(2):160-8. Epub 2015 Jul 18. PMID: 27158237

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Pubmed Data : Planta Med. 1991 Dec ;57(6):523-6. PMID: 1818342

Article Published Date : Nov 30, 1991

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Hepatoprotective

[+]

Anti-inflammatory activity of Rg3-enriched Korean red ginseng extract in murine model of sepsis.Dec 31, 2017

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Pubmed Data : Behav Med. 2011 Apr ;37(2):42-6. PMID: 21660771

Article Published Date : Mar 31, 2011

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean), Ginsenosides

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Phytotherapy, Plant Extracts

Problem Substances : Fluoxetine (trade name Prozac)

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Antrodia camphorata and Panax ginseng complex could be a potential formulation with an anti-fatigue pharmacological effect.Feb 19, 2018

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Pubmed Data : PLoS One. 2016 ;11(1):e0146843. Epub 2016 Jan 11. PMID: 26751692

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Ginseng, Ginsenosides

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Hyperglycemia

Pharmacological Actions : Anti-Apoptotic, Hypoglycemic Agents

Additional Keywords : Plant Extracts

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Black ginseng has ameliorative effects against acetaminophen induced hepatotoxicity.Apr 20, 2017

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Pubmed Data : Molecules. 2017 Apr 21 ;22(4). Epub 2017 Apr 21. PMID: 28430162

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Pubmed Data : Int J Reprod Biomed (Yazd). 2018 Nov ;16(11):711-718. PMID: 30775687

Article Published Date : Oct 31, 2018

Study Type : Animal Study

Additional Links

Substances : Ginseng (American)

Diseases : Chemotherapy-Induced Toxicity: Cyclophosphamide, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Chemoprotective Agents

[+]

Diol-ginsenosides from Korean Red Ginseng delay the development of type 1 diabetes in diabetes-prone biobreeding rats.Jun 30, 2020

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Pubmed Data : J Ginseng Res. 2020 Jul ;44(4):619-626. Epub 2019 Jun 12. PMID: 32617042

Article Published Date : Jun 30, 2020

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Anti-Obesity Agents

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Fermented ginseng improved alcohol liver injury in association with changes in the gut microbiota of mice.Aug 31, 2019

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Pubmed Data : Food Funct. 2019 Sep 1 ;10(9):5566-5573. Epub 2019 Aug 20. PMID: 31429848

Article Published Date : Aug 31, 2019

Study Type : Animal Study

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Substances : Fermented Foods and Beverages, Ginseng

Diseases : Alcoholic Liver Disease

Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective

Additional Keywords : Gut-liver axis

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Fermented ginseng was shown to possess hepatoprotective activity against paracetamol (APAP)-induced liver injury.Mar 31, 2015

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Pubmed Data : J Pharm Pharmacol. 2015 Apr ;67(4):565-72. Epub 2014 Dec 10. PMID: 25495794

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Pubmed Data : J Ginseng Res. 2019 Oct ;43(4):635-644. Epub 2019 Mar 7. PMID: 31695569

Article Published Date : Sep 30, 2019

Study Type : Animal Study

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Substances : Ginseng (Korean), Ginsenosides

Diseases : Allergic Rhinitis

Pharmacological Actions : interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation

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Fermented red ginseng might be a beneficial therapeutic approach for metabolic syndrome.Jun 15, 2016

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Pubmed Data : Biol Trace Elem Res. 2017 Jun ;177(2):331-344. Epub 2016 Nov 16. PMID: 27854046

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Pubmed Data : Nutrients. 2017 Aug 24 ;9(9). Epub 2017 Aug 24. PMID: 28837087

Article Published Date : Aug 23, 2017

Study Type : Animal Study

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Substances : Ginseng

Diseases : Alcohol Toxicity , Depression

Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator

Additional Keywords : Plant Extracts

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Ginseng extract reduces bacterial load and lung pathology in chronic P. aeruginosa pneumonia in rats.May 01, 1997

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Pubmed Data : Antimicrob Agents Chemother. 1997 May;41(5):961-4. PMID: 9145852

Article Published Date : May 01, 1997

Study Type : Animal Study

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Substances : Ginseng (Asian)

Diseases : Pneumonia, Pseudomonas aeruginosa

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Ginseng extract reduces tacrolimus-induced oxidative stress by modulating autophagy in pancreatic beta cells.Jul 30, 2017

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Pubmed Data : Lab Invest. 2017 Jul 31. Epub 2017 Jul 31. PMID: 28759009

Article Published Date : Jul 30, 2017

Study Type : Animal Study

Additional Links

Substances : Ginseng (Korean)

Diseases : Mitochondrial Dysfunction , Oxidative Stress

Pharmacological Actions : Antioxidants, Pancreato Protective Agents

Problem Substances : Tacrolimus

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Ginseng extracts may suppress the cognitive decline associated with aging.Sep 30, 2017

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Pubmed Data : Curr Neurovasc Res. 2010 Mar 31. Epub 2010 Mar 31. PMID: 20353383

Article Published Date : Mar 31, 2010

Study Type : Animal Study

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Substances : Ginsenosides

Diseases : Cerebral Aneurysm, Stroke, Subarachnoid hemorrhage

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Ginseng seed oil ameliorates hepatic lipid accumulation in vitro and in vivo.Sep 30, 2018

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Pubmed Data : J Ginseng Res. 2018 Oct ;42(4):419-428. Epub 2017 Apr 27. PMID: 30344430

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Pubmed Data : Cancer Lett. 1991 May 1;57(2):91-4. PMID: 9236860

Article Published Date : May 01, 1991

Study Type : Animal Study

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Substances : Ginseng, unspecified species

Diseases : Pseudomonas aeruginosa

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Ginseng was protective against RSV infection through multiple mechanisms, which include improving cell survival, partial inhibition of viral replication and modulation of cytokines. Dec 31, 2014

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Pubmed Data : Nutrients. 2015 ;7(2):1021-36. Epub 2015 Feb 4. PMID: 25658239

Article Published Date : Dec 31, 2014

Study Type : Animal Study, In Vitro Study

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Substances : Panax Ginseng

Diseases : Respiratory Syncytial Virus Infections

Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents

Additional Keywords : Dose Response

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Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress.May 24, 2020

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Pubmed Data : Behav Brain Res. 2020 May 25:112710. Epub 2020 May 25. PMID: 32464121

Article Published Date : May 24, 2020

Study Type : Animal Study

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Substances : Ginsenosides

Diseases : Brain Inflammation , Depression

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antidepressive Agents

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Ginsenoside 20(S)-Rg3 inhibited the Warburg effect in ovarian cancer cells via H19/miR-324-5p/PKM2 pathway.Dec 31, 2017

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Pubmed Data : Cell Physiol Biochem. 2018 ;51(3):1340-1353. Epub 2018 Nov 27. PMID: 30481782

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Pubmed Data : J Orthop Surg Res. 2019 Aug 14 ;14(1):259. Epub 2019 Aug 14. PMID: 31412899

Article Published Date : Aug 13, 2019

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Ischemia, Spinal Cord Injuries

Pharmacological Actions : Antioxidants

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Ginsenoside Rb1 alleviated high fat diet-induced apoptosis of hepatocytes of mice via PPAR-γ.Dec 31, 2019

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Pubmed Data : J Huazhong Univ Sci Technolog Med Sci. 2002 ;22(3):212-5. PMID: 12658806

Pubmed Data : Biomed Environ Sci. 2017 May ;30(5):363-372. PMID: 28549492

Article Published Date : Apr 30, 2017

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Cognitive Decline/Dysfunction, Inflammation, Oxidative Stress, Postoperative Recovery

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Ginsenoside Rb1 may be an effective treatment to prevent the secondary brain damage induced by stroke.Apr 17, 2017

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Pubmed Data : J Ethnopharmacol. 2017 Apr 18 ;202:138-146. Epub 2017 Jan 5. PMID: 28065779

Article Published Date : Apr 17, 2017

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Stroke: Attenuation/Recovery

Pharmacological Actions : Neuroprotective Agents

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View the Evidence: 1106 Abstracts with Ginseng Research

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A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.Dec 31, 2018

Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.Dec 31, 2019

Ginsenoside Rg3 for chemotherapy-induced myelosuppression.Dec 31, 2019

Panax ginseng extract may induce an improvement in blood lipid profile mainly by a reduction in total and LDL-cholesterol levels.Jul 13, 2019

This review provides positive evidence for the efficacy of ginseng on reducing blood pressure in patients with pre-hypertension and hypertension.Jul 11, 2017

The combination of omega-3 and Korean red ginseng may have beneficial effects in children with subthreshold ADHD.Aug 25, 2020

"North American ginseng extract, improves working memory in schizophrenia." Dec 30, 2011

Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex.Nov 17, 2019

American Ginseng (in combination with Ginkgo biloba) impoves symptoms of ADHD.May 01, 2001

American ginseng (Panax quinquefolius L.) has a positive effect on glycemic control in type 2 diabetes.Nov 30, 2012

American ginseng extract added to conventional treatment provided an effective and safe adjunct in the management of T2DM.Feb 23, 2018

American Ginseng has a neutral effect on blood pressure in hypertensive individuals.Aug 01, 2005

American Ginseng has no effect on 24-hour blood pressure and renal function in hypertensive individuals. Apr 01, 2006

American ginseng has radioprotective effect on human lymphocytes at 90 minutes postirradiation.May 01, 2010

American Ginseng is safe and effective in reducing relative risk and duration of respiratory symptoms associated with "cold and flu" in adults. Mar 01, 2006

American ginseng is safe, well tolerated, and potentially effective for preventing acute respiratory illness due to influenza and respiractory syncytial virus infections.Jan 01, 2004

American ginseng reduces high blood sugar after meals in both diabetic and nondiabetic subjects. Apr 10, 2000

American ginseng reduces oxidative stress in patients taking the antiviral medication zidovudine without altering drug pharmacokinetics. May 01, 2008

American ginseng tea protects cellular DNA within 2 h from consumption.Dec 31, 2014

An enzyme-modified ginseng extract treatment for 4 weeks decreased fatigue severity in a healthy population.Oct 31, 2016

Daily supplementation of Korean Red Ginseng for 8 weeks significantly improved the TBUT score and subjective dry eye symptoms, as compared to placebo.Dec 31, 2014

Daily supplementation with fermented red ginseng lowered postprandial glucose levels in subjects with impaired fasting glucose or type 2 diabetes.Jul 10, 2014

Echinacea purpurea and Panax ginseng enhance cellular immune function of peripheral blood mononuclear cells both from normal individuals and patients with depressed cellular immunity.Jan 01, 1997

Enzyme-treated red ginseng extract significantly improved eye wrinkle roughness, skin elasticity, and moisture content of skin. Jun 30, 2016

Ginsan significantly enhanced natural killer (NK) cell cytotoxic activity by 40% after administration for 14 weeks.Dec 31, 2013

Ginseng could improve glucose control and insulin sensitivity in patients with T2DM or impaired glucose intolerance.Jan 31, 2016

Ginseng extract improves quality of life and physiological symptoms of postmenopausal women. Jan 01, 1999

Ginseng improves pulmonary function and exercise capacity in patients with COPD. Nov 01, 2009

Ginseng improves the condition of patients with congestive heart failure and raises levels of T3 and T4. Apr 01, 1999

Ginsenoside Rb1 treatment was effective in reducing the extent of oxidative stress and inflammation in chronic kidney disease patients.Jan 31, 2017

Ginsenoside Rd is efficacious against acute ischemic stroke.Apr 30, 2016

Ginsenoside Rg3 could be used as a new regimen to delay acquired resistance of epidermal growth factor receptor-tyrosine kinase inhibitors.Oct 24, 2016

Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patients with acute leukemia.Dec 31, 2013

Ginsenoside-Rd improves outcome of acute ischaemic stroke.May 31, 2012

Ginsenoside-Rd may be of some benefit in acute ischaemic stroke.Apr 30, 2009

High-dose ginsenoside supplementation augmented the improvement of aerobic capacity by exercise training.Mar 31, 2018

Immuno-enhancement effects of Korean red ginseng in healthy adults.Dec 31, 2020

In this preliminary study korean red ginseng significantly lowered the incidences of acute respiratory infections. Nov 30, 2012

Korea red ginseng has therapeutic activity in treating Helicobacter pylori-induced halitosis:Jan 01, 2009

Korean ginseng improves treatment outcomes in HIV-infected patients on antiretroviral therapy. Aug 01, 2009

Korean red ginseng can be safely used as a health food to achieve clinical improvement of atopic dermatitis as well as improving overall quality of life.May 31, 2018

Korean Red Ginseng contain compounds which improve arterial stiffness in healthy individuals. Feb 04, 2010

Korean Red Ginseng could be used as a complementary therapy for chronic hepatitis B.Nov 30, 2016

Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemotherapy.Apr 30, 2020

Korean red ginseng lowers urinary BPA levels and BPA-induced malondialdehyde levels and alleviates gynecological complaints without side effects of raw-ginseng.Dec 31, 2013

Korean red ginseng may be a useful agent for the treatment of male infertility.Jun 30, 2016

Korean red ginseng may improve tinnitus symptoms and mental wellbeing in chronic tinnitus patients.Aug 31, 2015

Korean red ginseng might be effective in reducing pro-inflammatory cytokines and fatigue in overweight patients with NAFLD.Jun 30, 2016

Korean red ginseng might help to stabilize the sympathetic nervous system and improve cognition in individuals with high stress.Jun 30, 2019

Korean red ginseng prolongs survival in HIV-1 patients, possibly by slowing the decrease in CD4+ T-cell count.Mar 31, 2017

Korean red ginseng supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.Jul 16, 2012

Panax ginseng improves symptoms in men with erectile dysfunction. May 01, 2009

Panax ginseng is safe and improves cancer-related fatigue as well as overall quality of life, appetite, and sleep at night.Aug 31, 2015

Protective effect of Korean red ginseng on oxaliplatin-mediated splenomegaly in colon cancer.Aug 31, 2018

Protective effects of ginsenoside on myocardiac ischemic and reperfusion injuries.Sep 30, 1994

Red ginseng extract containing panaxynol and panaxydol can effectively control the symptoms of acne.Feb 28, 2019

Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin.Dec 01, 2009

The combination of transcatheter arterial chemoembolization and ginsenoside Rg3 may prolong overall survival when compared with it alone.Jul 31, 2016

The present study confirms the safety and tolerability of daily intake of 2g of Korean red ginseng for 24 weeks by healthy adults.Sep 30, 2018

These results suggest a potential role for ginseng in modulating salivary androgen levels.May 27, 2020

This data suggested that consumers on a Western diet should obtain better cancer prevention effects with American ginseng intake.Mar 31, 2017

This is the first study to test the efficacy of Cognition Support Formula® on cognition in older adults with subjective cognitive impairment.Jun 09, 2019

This study on healthy volunteers provides good evidence on the lack of bleeding risks of Curcuma longa, Angelica sinensis and Panax ginseng.Aug 14, 2017

Treatment with carnitine, acetyl carnitine, L-arginine and ginseng improves sperm motility and sexual health in men with asthenopermia.Sep 01, 2010

Twenty-four week administration of Korean red ginseng in diabetes patients resulted in a significant improvement in follistatin and SHBG levels.May 15, 2020

Vascular effects of combined enriched Korean red ginseng and American ginseng administration in individuals with hypertension and type 2 diabetes.Feb 29, 2020

Cytoprotective effects of ginsenoside Rd on apoptosis-associated cell death in the isolated human pancreatic islets.Dec 31, 2018

Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.Dec 23, 2016

Ginsenoside Rb1 shows potential for use in skin care products to protect the skin against damage by fine particles.Sep 08, 2019

Ginsenoside Rg1 can inhibit inflammatory responses in human chondrocytes in vitro and reduce articular cartilage damage in vivo.Mar 09, 2017

Korean red ginseng may protect against chemotherapy-induced alopecia.Mar 31, 2016

Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.May 08, 2012

Ginseng

View the Evidence:
1106 Abstracts with Ginseng Research